Detailed information for compound 981565

Basic information

Technical information
  • TDR Targets ID: 981565
  • Name: (1R,2S)-1-[[(2S,4R)-4-[8-bromo-7-methoxy-2-[2 -(propanoylamino)-1,3-thiazol-4-yl]quinolin-4 -yl]oxy-1-[(2S)-2-(cyclopentyloxycarbonylamin o)-3,3-dimethylbutanoyl]pyrrolidine-2-carbony l]amino]-2-ethenylcyclopropane-1-carboxylic a cid
  • MW: 855.794 | Formula: C39H47BrN6O9S
  • H donors: 4 H acceptors: 8 LogP: 5.87 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC(=O)Nc1scc(n1)c1cc(O[C@@H]2C[C@H](N(C2)C(=O)[C@H](C(C)(C)C)NC(=O)OC2CCCC2)C(=O)N[C@@]2(C[C@H]2C=C)C(=O)O)c2c(n1)c(Br)c(cc2)OC
  • InChi: 1S/C39H47BrN6O9S/c1-7-20-17-39(20,35(50)51)45-33(48)26-15-22(18-46(26)34(49)32(38(3,4)5)44-37(52)55-21-11-9-10-12-21)54-28-16-24(25-19-56-36(42-25)43-29(47)8-2)41-31-23(28)13-14-27(53-6)30(31)40/h7,13-14,16,19-22,26,32H,1,8-12,15,17-18H2,2-6H3,(H,44,52)(H,45,48)(H,50,51)(H,42,43,47)/t20-,22-,26+,32-,39-/m1/s1
  • InChiKey: DUIWCJRIQOLTHY-QCYNBGBQSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1R,2S)-1-[[(2S,4R)-4-[[8-bromo-7-methoxy-2-[2-(propanoylamino)thiazol-4-yl]-4-quinolyl]oxy]-1-[(2S)-2-(cyclopentoxycarbonylamino)-3,3-dimethyl-butanoyl]pyrrolidine-2-carbonyl]amino]-2-vinyl-cyclopropane-1-carboxylic acid
  • (1R,2S)-1-[[[(2S,4R)-4-[[8-bromo-7-methoxy-2-[2-(1-oxopropylamino)-4-thiazolyl]-4-quinolyl]oxy]-1-[(2S)-2-[(cyclopentoxy-oxomethyl)amino]-3,3-dimethyl-1-oxobutyl]-2-pyrrolidinyl]-oxomethyl]amino]-2-vinyl-1-cyclopropanecarboxylic acid
  • (1R,2S)-1-[[(2S,4R)-4-[[8-bromo-7-methoxy-2-(2-propionamidothiazol-4-yl)-4-quinolyl]oxy]-1-[(2S)-2-(cyclopentoxycarbonylamino)-3,3-dimethyl-butanoyl]pyrrolidine-2-carbonyl]amino]-2-vinyl-cyclopropane-1-carboxylic acid
  • (1R,2S)-1-[[(2S,4R)-4-[8-bromo-7-methoxy-2-[2-(propanoylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-1-[(2S)-2-(cyclopentyloxycarbonylamino)-3,3-dimethyl-butanoyl]pyrrolidin-2-yl]carbonylamino]-2-ethenyl-cyclopropane-1-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0039 0.0105
Brugia malayi Thioredoxin reductase 0.0198 0.0834 0.0834
Plasmodium vivax SET domain protein, putative 0.003 0.0057 0.0669
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0082 0.0082
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0047 0.0136 0.1635
Chlamydia trachomatis protoporphyrinogen oxidase 0.0046 0.0128 0.4706
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0015 0.0181
Loa Loa (eye worm) hypothetical protein 0.0049 0.0146 0.0146
Trichomonas vaginalis transmembrane protein nessy, putative 0.0026 0.0036 0.0225
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0135 0.0135
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.1104 0.1104
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0026 0.0069
Toxoplasma gondii hypothetical protein 0.0026 0.0039 0.0467
Loa Loa (eye worm) programmed cell death 8 0.0018 0.0001 0.0001
Echinococcus multilocularis protein patched 0.0042 0.0111 0.0111
Echinococcus multilocularis glutamate receptor 2 0.0337 0.1481 0.1481
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0024 0.0065
Toxoplasma gondii CAAX amino terminal protease family protein 0.0019 0.0005 0.0066
Giardia lamblia Telomerase catalytic subunit 0.009 0.0335 0.4725
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.018 0.018
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0026 0.031
Brugia malayi Receptor family ligand binding region containing protein 0.0064 0.0214 0.0214
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0093 0.0346 0.0346
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0057 0.018 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0057 0.0057
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0488 0.2181 0.2181
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0018 0.0001 0.0008
Plasmodium vivax glutathione reductase, putative 0.0198 0.0834 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0031 0.0372
Schistosoma mansoni neuroligin 3 (S09 family) 0.0367 0.1621 0.1621
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0066 0.0225 0.0225
Echinococcus multilocularis para nitrobenzyl esterase 0.0367 0.1621 0.1621
Schistosoma mansoni glutamate receptor kainate 0.0337 0.1481 0.1481
Schistosoma mansoni glutamate receptor kainate 0.0337 0.1481 0.1481
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0123 0.0488 0.0488
Echinococcus multilocularis glutamate receptor 2 0.0401 0.1777 0.1777
Trichomonas vaginalis porcupine, putative 0.0026 0.0036 0.0225
Loa Loa (eye worm) carboxylesterase 0.0367 0.1621 0.1621
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0123 0.0488 0.0488
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0068 0.0235 0.0235
Schistosoma mansoni hypothetical protein 0.0125 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0097 0.0369 0.0369
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.0036 0.0438
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0271 0.0754
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0367 0.1621 0.1621
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 0.0754
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0051 0.0154 0.2177
Echinococcus granulosus glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0064 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0082 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Brugia malayi jmjC domain containing protein 0.0025 0.0032 0.0032
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0051 0.0154 0.0154
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0024 0.0065
Brugia malayi Muscleblind-like protein 0.0148 0.0603 0.0603
Brugia malayi glutaminase DH11.1 0.0327 0.1434 0.1434
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Schistosoma mansoni sterol O-acyltransferase 1 0.0026 0.0036 0.0036
Echinococcus granulosus microtubule associated protein 2 0.0683 0.3088 0.3088
Schistosoma mansoni glutamate receptor NMDA 0.0917 0.4172 0.4172
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0601 0.2707 0.7558
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0036 0.0036
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0068 0.0235 0.0235
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0036 0.0036
Echinococcus granulosus neuroligin 0.0367 0.1621 0.1621
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0136 0.0136
Brugia malayi hypothetical protein 0.0057 0.018 0.018
Brugia malayi Carboxylesterase family protein 0.0367 0.1621 0.1621
Trypanosoma cruzi NADH dehydrogenase, putative 0.0018 0.0001 0.0015
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0123 0.0488 0.0488
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Loa Loa (eye worm) carboxylesterase 0.0367 0.1621 0.1621
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0005 0.0077
Schistosoma mansoni ATP-binding cassette transporter 0.0337 0.1481 0.1481
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0225
Echinococcus multilocularis short transient receptor potential channel 6 0.0077 0.0273 0.0273
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0018 0.0001 0.0001
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0123 0.0488 0.0488
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0458 0.0458
Loa Loa (eye worm) thioredoxin reductase 0.0198 0.0834 0.0834
Loa Loa (eye worm) hypothetical protein 0.0082 0.0299 0.0299
Mycobacterium tuberculosis Probable reductase 0.0307 0.1343 0.3748
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0307 0.1343 0.3748
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0401 0.1777 0.1777
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Loa Loa (eye worm) glutaminase 2 0.0327 0.1434 0.1434
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0068 0.0235 0.0652
Loa Loa (eye worm) jmjC domain-containing protein 0.0097 0.0366 0.0366
Brugia malayi SWIRM domain containing protein 0.0046 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0099
Brugia malayi Cation transporter family protein 0.0123 0.0488 0.0488
Giardia lamblia Hypothetical protein 0.0093 0.0346 0.4882
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0026 0.0069
Echinococcus granulosus transient receptor potential gamma protein 0.0116 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0123 0.0488 0.0488
Brugia malayi Glutamate receptor 2 precursor 0.0337 0.1481 0.1481
Entamoeba histolytica thioredoxin reductase, putative 0.0018 0.0001 0.0017
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.079 0.3581 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.022 0.2641
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0026 0.0036 0.0036
Plasmodium falciparum protoporphyrinogen oxidase 0.0046 0.0128 0.1526
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.3088 0.3088
Echinococcus multilocularis transient receptor potential ion channel A 0.0112 0.0438 0.0438
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0123 0.0488 0.0488
Toxoplasma gondii hypothetical protein 0.0026 0.0036 0.0438
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0136 0.0136
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0064 0.0214 0.0214
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0271 0.3253
Brugia malayi diacylglycerol acyltransferase 0.0026 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0225
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0199 0.0199
Echinococcus granulosus peregrin 0.0031 0.0062 0.0062
Brugia malayi MBOAT family protein 0.0026 0.0036 0.0036
Schistosoma mansoni amine oxidase 0.0046 0.0128 0.0128
Mycobacterium ulcerans oxidoreductase 0.0046 0.0128 0.0355
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0065 0.0219 0.1118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0018 0.0001 0.0015
Echinococcus multilocularis glycine receptor subunit beta 0.0123 0.0488 0.0488
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0123 0.0488 0.0488
Echinococcus granulosus expressed conserved protein 0.0092 0.0342 0.0342
Echinococcus multilocularis nAChR subunit 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0032 0.0386
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0051 0.0154 0.2177
Echinococcus multilocularis glutamate receptor 2 0.0276 0.1199 0.1199
Trichomonas vaginalis glutathione reductase, putative 0.0068 0.0235 0.1448
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Leishmania major glycerol uptake protein, putative 0.0026 0.0036 0.0438
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0042 0.0111 0.0111
Leishmania major glycerol uptake protein, putative 0.0026 0.0036 0.0438
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1008 0.6221
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0049 0.0049
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0026 0.031
Plasmodium falciparum telomerase reverse transcriptase 0.009 0.0335 0.4011
Brugia malayi Carboxylesterase family protein 0.0367 0.1621 0.1621
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0068 0.0235 0.2814
Brugia malayi Pre-SET motif family protein 0.0207 0.0876 0.0876
Brugia malayi hypothetical protein 0.0367 0.1621 0.1621
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0128 0.0128
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0123 0.0488 0.0488
Schistosoma mansoni zinc finger protein 0.0026 0.0036 0.0036
Onchocerca volvulus 0.0066 0.0225 0.1144
Chlamydia trachomatis hypothetical protein 0.0019 0.0005 0.0158
Brugia malayi jmjC domain containing protein 0.0153 0.0626 0.0626
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0536 0.0536
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0032 0.0372
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0563 0.0563
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0026 0.0069
Echinococcus granulosus short transient receptor potential channel 6 0.0077 0.0273 0.0273
Echinococcus granulosus metabotropic glutamate receptor 2 0.0064 0.0214 0.0214
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0092 0.0092
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0032 0.0032
Brugia malayi CXXC zinc finger family protein 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0125 0.0496 0.0496
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.022 0.022
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0046 0.0128 0.1526
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.007 0.0242 0.0242
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0183 0.2193
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0149 0.0149
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0111 0.0111
Echinococcus multilocularis muscleblind protein 0.0148 0.0603 0.0603
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0068 0.0235 0.2814
Echinococcus multilocularis glycine receptor subunit beta 0.0123 0.0488 0.0488
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.009 0.0335 0.402
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0032 0.0032
Echinococcus multilocularis zinc finger protein 0.0021 0.0014 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0032 0.0032
Brugia malayi Hhat protein 0.0026 0.0036 0.0036
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0039 0.0533
Onchocerca volvulus 0.0123 0.0488 0.2495
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0026 0.0069
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.1796 0.1796
Onchocerca volvulus 0.0064 0.0214 0.1088
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0036 0.0036
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0307 0.1343 0.3748
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0 0.0002
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.0198 0.0834 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0068 0.0235 0.0652
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.022 0.2641
Loa Loa (eye worm) GABA receptor subunit 0.0066 0.0225 0.0225
Schistosoma mansoni glutamate synthase 0.0018 0.0001 0.0001
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0024 0.0856
Brugia malayi Telomerase reverse transcriptase 0.024 0.103 0.103
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0367 0.1621 0.4523
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.1159
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0149 0.0413
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0036 0.0036
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0064 0.0214 0.0214
Brugia malayi mbt repeat family protein 0.0047 0.0136 0.0136
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0018 0.0001 0.0015
Brugia malayi Bromodomain containing protein 0.0038 0.0093 0.0093
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0046 0.0128 0.0128
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0026 0.0069
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0026 0.0036 0.0438
Trichomonas vaginalis apoptosis inducing factor, putative 0.0018 0.0001 0.0008
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0136 0.0136
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0051 0.0154 0.2177
Schistosoma mansoni hypothetical protein 0.004 0.0104 0.0104
Brugia malayi hypothetical protein 0.0057 0.018 0.018
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0051 0.0154 0.1852
Echinococcus multilocularis acetylcholinesterase 0.2173 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Echinococcus multilocularis nmda type glutamate receptor 0.062 0.2796 0.2796
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Loa Loa (eye worm) hypothetical protein 0.0034 0.0073 0.0073
Onchocerca volvulus 0.0026 0.0036 0.0181
Toxoplasma gondii selenide, water dikinase 0.0018 0.0001 0.0015
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0123 0.0488 0.0488
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0186 0.0781 0.0781
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0166 0.0166
Leishmania major extracellular receptor, putative 0.0064 0.0214 0.2561
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0186 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0367 0.1621 0.1621
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0171 0.0709 1
Brugia malayi hypothetical protein 0.0439 0.1952 0.1952
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.022 0.022
Echinococcus granulosus glutamate receptor 2 0.0276 0.1199 0.1199
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0031 0.0031
Brugia malayi Glutamate receptor 1 precursor 0.0337 0.1481 0.1481
Mycobacterium tuberculosis Probable integral membrane protein 0.0019 0.0005 0.0012
Echinococcus multilocularis cpg binding protein 0.0032 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0082 0.0082
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0026 0.0069
Mycobacterium tuberculosis Carboxylesterase LipT 0.0367 0.1621 0.4523
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0068 0.0235 0.2803
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0046 0.0128 0.0355
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.004 0.0104 0.0104
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0026 0.0364
Loa Loa (eye worm) hhat protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0051 0.0154 0.0154
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0198 0.0834 0.2325
Brugia malayi hypothetical protein 0.0046 0.0128 0.0128
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0051 0.0154 0.0154
Brugia malayi hypothetical protein 0.0299 0.1306 0.1306
Loa Loa (eye worm) hypothetical protein 0.0044 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0065 0.0219 0.0219
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0093 0.0346 0.0346
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0026 0.0026
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0128 0.1539
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0123 0.0488 0.0488
Trypanosoma brucei protein phosphatase 2B, putative 0.0051 0.0154 0.1852
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0024 0.0327
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0028 0.0028
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0066 0.0225 0.0225
Schistosoma mansoni amine oxidase 0.0046 0.0128 0.0128
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Echinococcus multilocularis neuroligin 0.0367 0.1621 0.1621
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0026 0.0069
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0367 0.1621 0.1621
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.1159
Entamoeba histolytica hypothetical protein 0.0025 0.0031 0.0438
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.1104 0.1104
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0125 0.0496 0.0496
Schistosoma mansoni transient receptor potential channel 0.0116 0.0456 0.0456
Schistosoma mansoni hypothetical protein 0.0168 0.0696 0.0696
Echinococcus granulosus glutamate synthase 0.0018 0.0001 0.0001
Leishmania major telomerase reverse transcriptase, putative 0.009 0.0335 0.402
Echinococcus multilocularis acetylcholinesterase 0.2173 1 1
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0123 0.0488 0.0488
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0026 0.0364
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0005 0.0012
Toxoplasma gondii hypothetical protein 0.0019 0.0005 0.0066
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.1159
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0046 0.0128 0.1526
Plasmodium falciparum glutathione reductase 0.0068 0.0235 0.2803
Brugia malayi Pre-SET motif family protein 0.003 0.0057 0.0057
Schistosoma mansoni cell adhesion molecule 0.0018 0.0001 0.0001
Echinococcus granulosus atrial natriuretic peptide receptor 0.0064 0.0214 0.0214
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0068 0.0235 0.2814
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0064 0.0214 0.0214
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0128 0.0128
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0271 0.0271
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0123 0.0488 0.0488
Brugia malayi Cation transporter family protein 0.0123 0.0488 0.0488
Brugia malayi metabotropic glutamate receptor type 2 0.0064 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Toxoplasma gondii NADPH-glutathione reductase 0.0068 0.0235 0.2814
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0039 0.0453
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Echinococcus multilocularis CAAX prenyl protease 2 0.0093 0.0346 0.0346
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0401 0.1777 0.1777
Echinococcus granulosus zinc finger protein 0.0021 0.0014 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Trypanosoma brucei CAAX amino terminal protease, putative 0.0093 0.0346 0.4152
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0125 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0051
Leishmania major hypothetical protein, conserved 0.0018 0.0001 0.0015
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0111 0.0111
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0031 0.0372
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0563 0.0563
Entamoeba histolytica vacuolar protein sorting 26 0.0026 0.0036 0.0515
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0036 0.0036
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Mycobacterium ulcerans glutaminase 0.0327 0.1434 0.4002
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0024 0.0065
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0166 0.0166
Brugia malayi hypothetical protein 0.0057 0.018 0.018
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0401 0.1777 0.1777
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0026 0.0036 0.0036
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0049 0.0049
Plasmodium falciparum glutathione reductase 0.0198 0.0834 1
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0043 0.0117 0.0117
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0136 0.0136
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Onchocerca volvulus Putative nachr subunit 0.0123 0.0488 0.2495
Loa Loa (eye worm) glutathione reductase 0.0198 0.0834 0.0834
Brugia malayi Transient-receptor-potential like protein 0.0043 0.0117 0.0117
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0057 0.0683
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0064 0.0214 0.0214
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0018 0.0001 0.0017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0026 0.0036 0.0424
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0015 0.0015
Echinococcus granulosus sterol O acyltransferase 1 0.0026 0.0036 0.0036
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 1
Loa Loa (eye worm) runx1 0.0055 0.0172 0.0172
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0036 0.0515
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0039 0.0453
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0123 0.0488 0.0488
Onchocerca volvulus 0.0123 0.0488 0.2495
Leishmania major UDP-galactopyranose mutase 0.0046 0.0128 0.1539
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 0.3813
Entamoeba histolytica CAAX prenyl protease family 0.0093 0.0346 0.4882
Leishmania major trypanothione reductase 0.0198 0.0834 1
Schistosoma mansoni hypothetical protein 0.004 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Schistosoma mansoni BC026374 protein (S09 family) 0.0367 0.1621 0.1621
Entamoeba histolytica hypothetical protein 0.0023 0.0024 0.0343
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0369 0.0369
Brugia malayi CHE-14 protein 0.0042 0.0111 0.0111
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0439 0.1952 0.1952
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.009 0.0335 0.402
Loa Loa (eye worm) hypothetical protein 0.0148 0.0603 0.0603
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0136 0.0136
Echinococcus granulosus hypothetical protein 0.0699 0.3159 0.3159
Leishmania major hypothetical protein, conserved 0.0025 0.0032 0.0386
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0171 0.0709 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0036 0.0438
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0051 0.0154 0.184
Loa Loa (eye worm) hypothetical protein 0.005 0.0148 0.0148
Treponema pallidum alginate O-acetylation protein (algI) 0.0026 0.0036 0.0498
Plasmodium vivax JmjC domain containing protein 0.0025 0.0032 0.0372
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0032 0.0386
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0125 0.0496 0.0496
Schistosoma mansoni cpg binding protein 0.0028 0.0049 0.0049
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0024 0.0856
Schistosoma mansoni nAChR subunit 0.0057 0.018 0.018
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0057 0.018 0.018
Loa Loa (eye worm) glutamate receptor 1 0.0337 0.1481 0.1481
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0036 0.0036
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0135 0.0135
Schistosoma mansoni tyrosine kinase 0.0065 0.0219 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0737 0.455
Echinococcus granulosus muscleblind protein 0.0148 0.0603 0.0603
Loa Loa (eye worm) hypothetical protein 0.2173 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0032
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0026 0.0036 0.0424
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0026 0.0036 0.0036
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.03 0.4226
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Loa Loa (eye worm) MBCTL1 0.0054 0.0166 0.0166
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0068 0.0235 0.0652
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0026 0.0069
Onchocerca volvulus 0.0047 0.0136 0.0691
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0005 0.0012
Echinococcus granulosus glutamate receptor 2 0.0401 0.1777 0.1777
Schistosoma mansoni glutamate receptor AMPA 0.0337 0.1481 0.1481
Onchocerca volvulus 0.0367 0.1621 0.83
Onchocerca volvulus 0.0082 0.0299 0.1526
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0696 0.3559
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0032 0.0386
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0092 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0051 0.0596
Brugia malayi Bromodomain containing protein 0.0031 0.0062 0.0062
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0093 0.0346 0.4152
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0065 0.0219 0.0219
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Echinococcus granulosus para nitrobenzyl esterase 0.0367 0.1621 0.1621
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 0.0754
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0082 0.0082
Echinococcus granulosus glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Echinococcus multilocularis sterol O acyltransferase 1 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0123 0.0488 0.0488
Mycobacterium ulcerans hypothetical protein 0.0019 0.0005 0.0012
Echinococcus multilocularis short transient receptor potential channel 6 0.0077 0.0273 0.0273
Brugia malayi CAAX amino terminal protease family protein 0.0093 0.0346 0.0346
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0068 0.0235 0.2803
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0046 0.0128 0.0355
Echinococcus granulosus roundabout 2 0.0018 0.0001 0.0001
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0369 0.0369
Schistosoma mansoni acetylcholinesterase 0.0367 0.1621 0.1621
Schistosoma mansoni bromodomain containing protein 0.0064 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.2173 1 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Schistosoma mansoni glutamate receptor kainate 0.0337 0.1481 0.1481
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0051 0.0154 0.0154
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0066 0.0225 0.0225
Schistosoma mansoni transient receptor potential channel 4 0.0116 0.0456 0.0456
Schistosoma mansoni glutaminase 0.0327 0.1434 0.1434
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0018 0.0001 0.0001
Schistosoma mansoni glutamate receptor AMPA 0.0337 0.1481 0.1481
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0123 0.0488 0.0488
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0012 0.0012
Mycobacterium ulcerans hypothetical protein 0.0023 0.0026 0.0069
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0051 0.0154 0.0154
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0051 0.0154 0.1852
Loa Loa (eye worm) carboxylesterase 0.2173 1 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0271 0.0271
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0026 0.0036 0.0036
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0026 0.0036 0.0438
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0366 0.0366
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0307 0.1343 0.3748
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0026 0.0036 0.0036
Brugia malayi hypothetical protein 0.0057 0.018 0.018
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Onchocerca volvulus 0.0235 0.1008 0.5162
Schistosoma mansoni hypothetical protein 0.0287 0.1249 0.1249
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0066 0.0225 0.3166
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0057 0.018 0.018
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0358 0.1577 0.44
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0123 0.0488 0.0488
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0018 0.0001 0.0001
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0026 0.0036 0.0036
Echinococcus granulosus carboxylesterase 5A 0.2173 1 1
Echinococcus granulosus cpg binding protein 0.0032 0.0065 0.0065
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0018 0.0001 0.0015
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0018 0.0001 0.0015
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.0219 0.0219
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0082 0.0082
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0024 0.0278
Leishmania major glycerol uptake protein, putative 0.0026 0.0036 0.0438
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Trichomonas vaginalis glutamate synthase, putative 0.0018 0.0001 0.0008
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0123 0.0488 0.0488
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0036 0.0036
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0153 0.0626 0.0626
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0135 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0026 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0049 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0128 0.1526
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0001 0.0015
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0401 0.1777 0.1777
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0149 0.0413
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0068 0.0235 0.0652
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.022 0.3105
Echinococcus multilocularis roundabout 2 0.0018 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Giardia lamblia PHD finger protein 15 0.0029 0.0051 0.0717
Schistosoma mansoni nAChR subunit 0.0057 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0036
Schistosoma mansoni sulfide quinone reductase 0.0018 0.0001 0.0001
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0018 0.0001 0.0015
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0358 0.1577 0.44
Echinococcus granulosus acetylcholinesterase 0.2173 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0225
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0019 0.0007 0.0007
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0046 0.0128 0.0128
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0093 0.0346 0.4152
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0128 0.1526
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0057 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0299 0.1306 0.1306
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0018 0.0001 0.0001
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0028 0.0028
Onchocerca volvulus 0.0367 0.1621 0.83
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0032 0.0386
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0026 0.0364
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0149 0.0413
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Echinococcus granulosus nAChR subunit 0.0066 0.0225 0.0225
Loa Loa (eye worm) ACC-1 protein 0.0123 0.0488 0.0488
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0026 0.0036 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0046 0.0128 0.0355
Mycobacterium tuberculosis Probable dehydrogenase 0.0307 0.1343 0.3748
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0046 0.0128 0.0128
Schistosoma mansoni sulfide quinone reductase 0.0018 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0066 0.0225 0.0225
Schistosoma mansoni glutamate synthase 0.0018 0.0001 0.0001
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0123 0.0488 0.0488
Echinococcus granulosus jumonji domain containing protein 0.004 0.0103 0.0103
Onchocerca volvulus 0.0439 0.1952 1
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.033 0.1448 0.7416
Echinococcus granulosus acetylcholinesterase 0.2173 1 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0166 0.0166
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0051 0.0051
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.3088 0.3088
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0051 0.0154 0.2177
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0024 0.0065
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0036 0.0515
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0128
Brugia malayi PHD-finger family protein 0.0029 0.0051 0.0051
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0057 0.018 0.018
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0026 0.0036 0.0036
Toxoplasma gondii thioredoxin reductase 0.0198 0.0834 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0299 0.0299
Trypanosoma cruzi NADH dehydrogenase, putative 0.0018 0.0001 0.0015
Echinococcus multilocularis receptor type guanylyl cyclase 0.0065 0.0219 0.0219
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0031 0.0031
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0111 0.0111
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0271 0.3243
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0032 0.0032
Brugia malayi jmjC domain containing protein 0.0025 0.0032 0.0032
Trypanosoma brucei trypanothione reductase 0.0198 0.0834 1
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0093 0.0346 0.2136
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.0219 0.0219
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0166 0.0166
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0018 0.0001 0.0015
Toxoplasma gondii histone lysine-specific demethylase 0.0046 0.0128 0.1539
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0051 0.0154 0.1852
Echinococcus granulosus tyrosine kinase 0.0065 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Giardia lamblia Thioredoxin reductase 0.0018 0.0001 0.0017
Echinococcus granulosus glutamate NMDA receptor subunit 0.0917 0.4172 0.4172
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0068 0.0235 0.2814
Mycobacterium ulcerans hypothetical protein 0.0019 0.0005 0.0012
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0018 0.0001 0.0015
Onchocerca volvulus 0.0367 0.1621 0.83
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0458 0.0458
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0439 0.1952 0.1952
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0136 0.0136
Treponema pallidum NADH oxidase 0.0068 0.0235 0.3296
Onchocerca volvulus Alhambra homolog 0.0029 0.0051 0.0254
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0032 0.0386
Giardia lamblia Fructose-bisphosphate aldolase 0.0171 0.0709 1
Onchocerca volvulus 0.0057 0.018 0.0918
Schistosoma mansoni protein phosphatase-2b 0.0051 0.0154 0.0154
Echinococcus granulosus short transient receptor potential channel 6 0.0077 0.0273 0.0273
Schistosoma mansoni zinc finger protein 0.0021 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0032 0.0065 0.0065
Echinococcus granulosus nAChR subunit 0.0123 0.0488 0.0488
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0369 0.0369
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0064 0.0214 0.0214
Onchocerca volvulus 0.003 0.0057 0.0286
Leishmania major serine/threonine protein phosphatase, putative 0.0051 0.0154 0.1852
Echinococcus multilocularis 0.0046 0.0128 0.0128
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0299 0.0299
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0005 0.0077
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0032 0.0032
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 0.3243
Schistosoma mansoni acetylcholine receptor subunit beta 0.0057 0.018 0.018
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0031 0.0031
Echinococcus multilocularis expressed conserved protein 0.0092 0.0342 0.0342
Echinococcus granulosus nmda type glutamate receptor 0.062 0.2796 0.2796
Schistosoma mansoni protein phosphatase-2b 0.0051 0.0154 0.0154
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0051 0.0154 0.0154
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.018 0.018
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0036 0.0036
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0068 0.0235 0.0235
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0036 0.0438
Loa Loa (eye worm) hypothetical protein 0.0047 0.0135 0.0135
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0369 0.5207
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0299 0.0299
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0057 0.0057
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0046 0.0128 0.1526
Mycobacterium ulcerans monoamine oxidase 0.0046 0.0128 0.0355
Echinococcus multilocularis Protein lozenge 0.0055 0.0172 0.0172
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0051 0.061
Entamoeba histolytica hypothetical protein 0.0026 0.0036 0.0515
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0051 0.0154 0.2177
Plasmodium vivax telomerase reverse transcriptase, putative 0.009 0.0335 0.4011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0018 0.0001 0.0017
Schistosoma mansoni hypothetical protein 0.004 0.0104 0.0104
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0036 0.0515
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0307 0.1343 0.3748
Brugia malayi MBOAT family protein 0.0026 0.0036 0.0036
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0066 0.0225 0.0225
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0057 0.018 0.018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0018 0.0001 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0271 0.3253
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0068 0.0235 0.2814
Brugia malayi amine oxidase, flavin-containing family protein 0.0046 0.0128 0.0128
Loa Loa (eye worm) acetylcholine receptor protein 0.0057 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0214 0.0214
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Brugia malayi Serotonin receptor 0.0469 0.2093 0.2093
Loa Loa (eye worm) hypothetical protein 0.0047 0.0136 0.0136
Onchocerca volvulus 0.0123 0.0488 0.2495
Entamoeba histolytica hypothetical protein 0.0064 0.0214 0.3011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Schistosoma mansoni metabotropic glutamate receptor 0.0064 0.0214 0.0214
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0024 0.0292
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Echinococcus granulosus metabotropic glutamate receptor 5 0.0064 0.0214 0.0214
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0018 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0026 0.0026
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 1
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0125 0.0496 0.0496
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0031 0.0372
Schistosoma mansoni protein kinase 0.0065 0.0219 0.0219
Schistosoma mansoni patched 1 0.0042 0.0111 0.0111
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0032 0.0032
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Trypanosoma cruzi GUP1, putative 0.0026 0.0036 0.0438
Schistosoma mansoni disulfide oxidoreductase 0.0018 0.0001 0.0001
Leishmania major NADH dehydrogenase, putative 0.0018 0.0001 0.0015
Schistosoma mansoni metabotropic glutamate receptor 0.0064 0.0214 0.0214
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0166 0.0166
Echinococcus granulosus glycine receptor subunit alpha 1 0.0123 0.0488 0.0488
Brugia malayi MBOAT family protein 0.0026 0.0036 0.0036
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0026 0.0036 0.0036
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0136 0.0136
Leishmania major glycerol uptake protein, putative 0.0026 0.0036 0.0438
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0036 0.0036
Loa Loa (eye worm) ACC-1 protein 0.0123 0.0488 0.0488
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0068 0.0235 0.2803
Echinococcus multilocularis tyrosine kinase 0.0065 0.0219 0.0219
Plasmodium vivax thioredoxin reductase, putative 0.0198 0.0834 1
Loa Loa (eye worm) acetylcholinesterase 1 0.2173 1 1
Schistosoma mansoni hypothetical protein 0.0029 0.0051 0.0051
Loa Loa (eye worm) glutamate receptor 2 0.0337 0.1481 0.1481
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.079 0.3581 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0066 0.0225 0.0225
Echinococcus granulosus dnaJ subfamily B 0.0405 0.1796 0.1796
Trichomonas vaginalis glutamate synthase, putative 0.0018 0.0001 0.0008
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0018 0.0001 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0307 0.1343 0.3748
Treponema pallidum fructose-bisphosphate aldolase 0.0171 0.0709 1
Echinococcus multilocularis muscleblind protein 1 0.0148 0.0603 0.0603
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0026 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Brugia malayi Metabotropic glutamate receptor precursor. 0.0064 0.0214 0.0214
Brugia malayi hypothetical protein 0.0057 0.018 0.018
Brugia malayi mbt repeat family protein 0.0047 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0148 0.0603 0.0603
Schistosoma mansoni transient receptor potential channel 0.0077 0.0273 0.0273
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0024 0.0292
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0367 0.1621 0.4523
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0054 0.0166 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Schistosoma mansoni hypothetical protein 0.0405 0.1796 0.1796
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0123 0.0488 0.0488
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0136 0.0136
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0018 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Onchocerca volvulus 0.0123 0.0488 0.2495
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0068 0.0235 0.2814
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Giardia lamblia NADH oxidase lateral transfer candidate 0.0068 0.0235 0.3308
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0026 0.0036 0.0036
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0018 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Trypanosoma cruzi GUP1, putative 0.0026 0.0036 0.0438
Echinococcus multilocularis carboxylesterase 5A 0.2173 1 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0018 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0026 0.0036 0.0036
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.2173 1 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0123 0.0488 0.0488
Echinococcus multilocularis geminin 0.0168 0.0696 0.0696
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0064 0.0214 0.0214
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0018 0.0001 0.0017
Onchocerca volvulus 0.0299 0.1306 0.6686
Onchocerca volvulus 0.0023 0.0026 0.0126
Plasmodium falciparum phd finger protein, putative 0.0029 0.0051 0.0596
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.022 0.022
Plasmodium falciparum thioredoxin reductase 0.0068 0.0235 0.2803
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0057 0.018 0.018
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0123 0.0488 0.0488
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0036 0.0515
Brugia malayi MBOAT family protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0076 0.0271 0.0271
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0032 0.0032
Plasmodium falciparum thioredoxin reductase 0.0198 0.0834 1
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0051 0.0051
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0018 0.0001 0.0001
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0057 0.018 0.018
Leishmania major hypothetical protein, conserved 0.0018 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Brugia malayi jmjC domain containing protein 0.0097 0.0366 0.0366
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0146 0.0146
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0043 0.0117 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Schistosoma mansoni acetylcholine receptor-related 0.0057 0.018 0.018
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0018 0.0001 0.0001
Echinococcus multilocularis NMDA receptor 0.0125 0.0496 0.0496
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0401 0.1777 0.1777
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0018 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0123 0.0488 0.0488
Loa Loa (eye worm) hhat protein 0.0026 0.0036 0.0036
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0032 0.0032
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0647 0.2919 0.8149
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0018 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0125 0.0496 0.0496
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0051 0.0154 0.2177
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0057 0.018 0.018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0018 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.1159
Echinococcus granulosus glycine receptor subunit beta 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0116 0.0456 0.0456
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0737 0.455
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0125 0.0496 0.0496
Toxoplasma gondii RNA-directed DNA polymerase 0.009 0.0335 0.402
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0051 0.061
Mycobacterium ulcerans integral membrane protein 0.0019 0.0005 0.0012
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.022 0.2641
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0026 0.031
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.022 0.022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0031 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0123 0.0488 0.0488
Schistosoma mansoni gliotactin 0.0367 0.1621 0.1621
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0026 0.0036 0.0036
Onchocerca volvulus 0.0057 0.018 0.0918
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.018 0.018
Schistosoma mansoni transient receptor potential channel 0.0077 0.0273 0.0273
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0876 0.0876
Echinococcus multilocularis protoporphyrinogen oxidase 0.0046 0.0128 0.0128
Onchocerca volvulus 0.0057 0.018 0.0918
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0032 0.0032
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0123 0.0488 0.0488
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.004 0.0104 0.0104
Onchocerca volvulus 0.0066 0.0225 0.1144
Plasmodium vivax protease, putative 0.0019 0.0005 0.0051
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0051 0.0155 0.0155
Entamoeba histolytica disulphide oxidoreductase, putative 0.0018 0.0001 0.0017
Echinococcus multilocularis nAChR subunit 0.0066 0.0225 0.0225
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Echinococcus multilocularis glutamate receptor NMDA 0.0496 0.2217 0.2217
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0024 0.0278
Echinococcus granulosus nmda type glutamate receptor 0.056 0.2514 0.2514
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0018 0.0001 0.0001
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.0219 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Brugia malayi hypothetical protein 0.0064 0.0214 0.0214
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0128 0.1526
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0128 0.1539
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0123 0.0488 0.0488
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0024 0.0292
Echinococcus multilocularis nmda type glutamate receptor 0.056 0.2514 0.2514
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0057 0.018 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0031 0.0192
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0026 0.0036 0.0036
Brugia malayi Carboxylesterase family protein 0.2173 1 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0136 0.0691
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.005 0.015 0.015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0026 0.0069
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0018 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0103 0.0103
Echinococcus granulosus BC026374 protein S09 family 0.0367 0.1621 0.1621
Loa Loa (eye worm) glutaminase 0.0327 0.1434 0.1434
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0018 0.0001 0.0001
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.022 0.2641
Loa Loa (eye worm) hypothetical protein 0.0065 0.0219 0.0219
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0271 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0123 0.0488 0.0488
Echinococcus granulosus glutamate receptor subunit protein glur 0.0125 0.0496 0.0496
Schistosoma mansoni glutamate receptor NMDA 0.0897 0.4077 0.4077
Schistosoma mansoni neurotransmitter gated ion channel 0.0066 0.0225 0.0225
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0051 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1104 0.681
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.022 0.022
Schistosoma mansoni lozenge 0.0055 0.0172 0.0172
Leishmania major hypothetical protein, conserved 0.0018 0.0001 0.0015
Echinococcus multilocularis lysine specific demethylase 5A 0.0093 0.0349 0.0349
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0128 0.0355
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0068 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0073 0.0255 0.0255
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0018 0.0001 0.0015
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Leishmania major glycerol uptake protein, putative 0.0026 0.0036 0.0438
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0018 0.0001 0.0001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.079 0.3581 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0171 0.0709 0.4376
Echinococcus granulosus receptor type guanylyl cyclase 0.0065 0.0219 0.0219
Mycobacterium ulcerans carboxylesterase, LipT 0.0367 0.1621 0.4523
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0123 0.0488 0.0488
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0001 0.0015
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0051 0.0154 0.1852
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0007 0.0007
Echinococcus granulosus CAAX prenyl protease 2 0.0093 0.0346 0.0346
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0367 0.1621 0.1621
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0111 0.0685
Brugia malayi jmjC domain containing protein 0.0025 0.0032 0.0032
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0068 0.0235 0.2803
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0401 0.1777 0.1777
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0036 0.0082 0.0082
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0068 0.0235 0.2814
Leishmania major hypothetical protein, conserved 0.0026 0.0036 0.0438
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0068 0.0235 0.8644
Brugia malayi Guanylyl cyclase protein 23 0.0065 0.0219 0.0219
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0146 0.0146
Trichomonas vaginalis mercuric reductase, putative 0.0068 0.0235 0.1448
Schistosoma mansoni hypothetical protein 0.0168 0.0696 0.0696
Brugia malayi glutathione reductase 0.0198 0.0834 0.0834
Echinococcus granulosus glutamate receptor NMDA 0.0496 0.2217 0.2217
Echinococcus granulosus phd:f box containing protein 0.0025 0.0032 0.0032
Onchocerca volvulus 0.0028 0.0049 0.0244
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.005 0.015 0.015
Treponema pallidum hypothetical protein 0.0019 0.0005 0.006
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0036 0.0036
Giardia lamblia Glutamate synthase 0.0018 0.0001 0.0017
Brugia malayi glutamate synthase 0.0018 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0032 0.0065 0.0065
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0367 0.1621 1
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Echinococcus granulosus geminin 0.0168 0.0696 0.0696
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0018 0.0001 0.0001
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0018 0.0001 0.0008
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0001 0.0008
Brugia malayi Cation transporter family protein 0.0123 0.0488 0.0488
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0018 0.0001 0.0015
Echinococcus multilocularis BC026374 protein (S09 family) 0.0367 0.1621 0.1621
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0032 0.0032
Brugia malayi Bromodomain containing protein 0.0076 0.0269 0.0269
Echinococcus multilocularis glutamate synthase 0.0018 0.0001 0.0001
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0032 0.0032
Echinococcus granulosus glycine receptor subunit beta 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0647 0.2919 0.8149
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0135 0.0135
Brugia malayi hypothetical protein 0.0036 0.0082 0.0082
Onchocerca volvulus 0.0367 0.1621 0.83
Echinococcus granulosus TRP transient receptor potential channel 0.0043 0.0117 0.0117
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Brugia malayi PHD-finger family protein 0.0026 0.0039 0.0039
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0068 0.0235 0.8644
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.018
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0036 0.0438
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Schistosoma mansoni glutamate synthase 0.0018 0.0001 0.0001
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0018 0.0001 0.0001
Trypanosoma cruzi extracellular receptor, putative 0.0064 0.0214 0.2561
Echinococcus multilocularis peregrin 0.0031 0.0062 0.0062
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0299 0.0299
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0367 0.1621 0.1621
Onchocerca volvulus 0.0367 0.1621 0.83
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0018 0.0001 0.0015
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0018 0.0001 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.018 0.018
Echinococcus granulosus lysine specific demethylase 5A 0.0097 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0018 0.0001 0.0015
Schistosoma mansoni nAChR subunit 0.0123 0.0488 0.0488
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0001 0.0015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0068 0.0235 0.2814
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0068 0.0235 0.2814
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0051 0.0154 0.184
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0024 0.0292
Schistosoma mansoni hypothetical protein 0.0034 0.0073 0.0073
Brugia malayi excitatory GABA receptor EXP-1A 0.0123 0.0488 0.0488
Loa Loa (eye worm) LGC-31 protein 0.0123 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0032
Onchocerca volvulus 0.0065 0.0219 0.1118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0068 0.0235 0.2814
Toxoplasma gondii hypothetical protein 0.0019 0.0005 0.0066
Onchocerca volvulus 0.0046 0.0128 0.0651
Brugia malayi MH2 domain containing protein 0.0117 0.0458 0.0458
Trypanosoma brucei NADH dehydrogenase 0.0018 0.0001 0.0015
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0057 0.018 0.018
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.3716 0.3716
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0068 0.0235 0.2814
Brugia malayi MBOAT family protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) glutamate receptor 0.0064 0.0214 0.0214
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0018 0.0001 0.0017
Brugia malayi Probable ClpP-like protease 0.0076 0.0271 0.0271
Trichomonas vaginalis spcc417.12 protein, putative 0.0367 0.1621 1
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0093 0.0346 0.4152
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0123 0.0488 0.0488
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0082 0.0082
Brugia malayi jmjC domain containing protein 0.0025 0.0032 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0194 0.0194
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.03 0.4226
Echinococcus granulosus thioredoxin glutathione reductase 0.0198 0.0836 0.0836
Plasmodium falciparum protease, putative 0.0019 0.0005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0066 0.0225 0.0225
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0367 0.1621 0.1621
Onchocerca volvulus 0.0123 0.0488 0.2495
Brugia malayi Carboxylesterase family protein 0.0367 0.1621 0.1621
Echinococcus granulosus transient receptor potential ion channel A 0.0112 0.0438 0.0438
Mycobacterium ulcerans dehydrogenase 0.0046 0.0128 0.0355
Trichomonas vaginalis glutaminase, putative 0.0327 0.1434 0.8848
Echinococcus multilocularis protein dispatched 1 0.0048 0.0138 0.0138
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0696 0.4292
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0123 0.0488 0.0488
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0401 0.1777 0.1777
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0917 0.4172 0.4172
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0123 0.0488 0.0488
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.0036 0.0438
Mycobacterium tuberculosis Probable oxidoreductase 0.0358 0.1577 0.44
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Brugia malayi Receptor family ligand binding region containing protein 0.0065 0.0219 0.0219
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0123 0.0488 0.0488
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0032 0.0032
Echinococcus multilocularis thioredoxin glutathione reductase 0.0198 0.0836 0.0836
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0401 0.1777 0.1777
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0358 0.1577 0.44
Trypanosoma brucei telomerase reverse transcriptase 0.009 0.0335 0.402
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0111 0.0111
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0153 0.0626 0.0626
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0051 0.0154 0.1852
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0073 0.0073
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0068 0.0235 0.8644
Loa Loa (eye worm) hypothetical protein 0.0123 0.0488 0.0488
Onchocerca volvulus 0.0123 0.0488 0.2495
Brugia malayi Carboxylesterase family protein 0.0367 0.1621 0.1621
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0018 0.0001 0.0001
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0093 0.0346 0.0346
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0123 0.0488 0.0488
Echinococcus multilocularis transient receptor potential gamma protein 0.0116 0.0456 0.0456
Echinococcus multilocularis conserved hypothetical protein 0.0689 0.3115 0.3115

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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