Detailed information for compound 1031853

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 388.933 | Formula: C16H21ClN2O3S2
  • H donors: 2 H acceptors: 3 LogP: 3.26 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCNCc1ccc(cc1)C(=O)c1csc(c1)S(=O)(=O)N.Cl
  • InChi: 1S/C16H20N2O3S2.ClH/c1-2-3-8-18-10-12-4-6-13(7-5-12)16(19)14-9-15(22-11-14)23(17,20)21;/h4-7,9,11,18H,2-3,8,10H2,1H3,(H2,17,20,21);1H
  • InChiKey: LJXHMWIGKDGACE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0251 0.2212 0.5276
Leishmania major nucleoside phosphorylase-like protein 0.0089 0.0671 0.0667
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0027 0.0099
Schistosoma mansoni amine GPCR 0.0028 0.0087 0.0084
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0453 0.1159
Mycobacterium tuberculosis Hypothetical protein 0.006 0.0396 0.0945
Schistosoma mansoni hypothetical protein 0.0665 0.6161 0.616
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.008 0.0584 0.058
Schistosoma mansoni carbonic anhydrase 0.0034 0.0144 0.0141
Schistosoma mansoni intermediate filament proteins 0.009 0.0679 0.0676
Onchocerca volvulus 0.0028 0.0087 0.0073
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0087 0.0084
Schistosoma mansoni histone deacetylase 1 2 3 0.0106 0.0835 0.0832
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0584 0.114
Onchocerca volvulus 0.0072 0.0509 0.0911
Brugia malayi MH2 domain containing protein 0.0137 0.1133 0.113
Schistosoma mansoni sex comb on midleg homolog 0.0107 0.0842 0.0839
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.0188 0.0831
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0509 0.0506
Brugia malayi histone deacetylase 1 (HD1) 0.0247 0.2174 0.2172
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.009 0.0681 0.3111
Loa Loa (eye worm) hypothetical protein 0.009 0.0681 0.0677
Echinococcus multilocularis histone deacetylase 6 0.0235 0.2062 0.206
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0144 0.0139
Loa Loa (eye worm) hypothetical protein 0.0372 0.337 0.337
Entamoeba histolytica hypothetical protein 0.0089 0.0671 0.3071
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.1302 0.1299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.006 0.0398 0.09
Loa Loa (eye worm) thioredoxin reductase 0.011 0.0871 0.0867
Brugia malayi RE15519p 0.0028 0.0087 0.0082
Toxoplasma gondii hypothetical protein 0.0032 0.0126 0.0547
Schistosoma mansoni methylthioadenosine phosphorylase 0.0089 0.0671 0.0668
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Loa Loa (eye worm) hypothetical protein 0.0155 0.1302 0.1299
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Entamoeba histolytica histone deacetylase, putative 0.0247 0.2174 1
Echinococcus granulosus neuropeptide receptor 0.0028 0.0087 0.0084
Schistosoma mansoni hypothetical protein 0.0028 0.0087 0.0084
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 0.1786
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Loa Loa (eye worm) hypothetical protein 0.0122 0.0983 0.0979
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0429 0.3912 1
Echinococcus granulosus microtubule associated protein 2 0.0682 0.6324 0.6323
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.009 0.0679 0.0675
Echinococcus granulosus neuropeptide receptor A26 0.0518 0.4763 0.4761
Trypanosoma brucei histone deacetylase 2 0.0106 0.0835 0.0831
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0002
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0089 0.0671 0.0667
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.009 0.0681 0.3111
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0092 0.0699 0.168
Echinococcus multilocularis purine nucleoside phosphorylase 0.034 0.3066 0.3064
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0509 0.0504
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0087 0.0082
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0259 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0133 0.1094 0.1091
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.011 0.0871 0.2078
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0007 0.0002
Mycobacterium ulcerans epimerase 0.0024 0.005 0.0128
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0019 0.0007 0.0004
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0035 0.003
Loa Loa (eye worm) hypothetical protein 0.0145 0.1207 0.1204
Echinococcus multilocularis histone deacetylase 8 0.0106 0.0835 0.0832
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0251 0.2212 0.5276
Onchocerca volvulus 0.0028 0.0087 0.0073
Echinococcus granulosus allatostatin A receptor 0.0028 0.0087 0.0084
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0019 0.0007 0.0002
Schistosoma mansoni hypothetical protein 0.0025 0.0058 0.0055
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0087 0.0082
Brugia malayi mbt repeat family protein 0.0107 0.0842 0.0838
Schistosoma mansoni biogenic amine receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis nmda type glutamate receptor 0.008 0.0585 0.0583
Echinococcus granulosus carbonic anhydrase 0.0034 0.0144 0.0141
Schistosoma mansoni hypothetical protein 0.048 0.4396 0.4394
Brugia malayi Importin beta-1 subunit 0.0028 0.0091 0.0086
Schistosoma mansoni histone deacetylase 0.0247 0.2174 0.2171
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.0188 0.0182
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 0.3191
Toxoplasma gondii histone deacetylase HDAC4 0.0106 0.0835 0.3819
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0007 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0671 0.1312
Brugia malayi Histone deacetylase 1 0.0247 0.2174 0.2172
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis DNA helicase recq, putative 0.0072 0.0514 0.1003
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0765 0.0762
Schistosoma mansoni histone deacetylase 0.0247 0.2174 0.2171
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0251 0.2212 0.5598
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0089 0.0671 0.3071
Schistosoma mansoni opsin-like receptor 0.0028 0.0087 0.0084
Brugia malayi Dopamine receptor protein 2 0.0028 0.0087 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0765 0.0762
Entamoeba histolytica hypothetical protein 0.0023 0.0041 0.0163
Brugia malayi Pre-SET motif family protein 0.0071 0.0499 0.0495
Treponema pallidum ATP-dependent DNA helicase 0.0022 0.0035 0.05
Echinococcus multilocularis GPCR, family 2 0.0049 0.0292 0.0289
Schistosoma mansoni hypothetical protein 0.0028 0.0087 0.0084
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0087 0.0082
Onchocerca volvulus 0.0126 0.1026 0.1938
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.008 0.0584 0.1481
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0259 0.05
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0087 0.0084
Onchocerca volvulus 0.0028 0.0087 0.0073
Brugia malayi RNA, U transporter 1 0.0079 0.0582 0.0577
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0087 0.0084
Schistosoma mansoni ap endonuclease 0.008 0.0584 0.0581
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0019 0.0007 0.0004
Loa Loa (eye worm) glutathione reductase 0.011 0.0871 0.0867
Onchocerca volvulus 0.0028 0.0087 0.0073
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0051 0.0314 0.0685
Onchocerca volvulus 0.009 0.0679 0.125
Schistosoma mansoni DNA polymerase eta 0.0019 0.0005 0.0002
Plasmodium falciparum thioredoxin reductase 0.011 0.0871 0.3988
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0509 0.0991
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0509 0.1213
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0035 0.003
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Echinococcus granulosus thioredoxin glutathione reductase 0.011 0.0871 0.0869
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0091 0.0086
Mycobacterium tuberculosis Probable reductase 0.0251 0.2212 0.5276
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0279 0.2479 0.5911
Trypanosoma brucei histone deacetylase 4 0.0222 0.1941 0.1939
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0087 0.0073
Schistosoma mansoni hypothetical protein 0.1068 1 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.0188 0.0182
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0087 0.0084
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0231 0.0228
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.006 0.0398 0.0948
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0087 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0087 0.0082
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0437 0.3986 0.3984
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0087 0.0084
Toxoplasma gondii thioredoxin reductase 0.011 0.0871 0.3988
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0479
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0185
Schistosoma mansoni peptidase Clp (S14 family) 0.0092 0.0699 0.0696
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0147 0.1227 0.1223
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0509 0.13
Entamoeba histolytica recQ family DNA helicase 0.0022 0.0035 0.0136
Onchocerca volvulus 0.0552 0.5082 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0648 0.0645
Brugia malayi beta-lactamase 0.0072 0.0509 0.0504
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.0188 0.0831
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0063 0.0057
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0507 0.0504
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0259 0.0254
Echinococcus multilocularis zinc finger protein 0.0027 0.0082 0.0079
Toxoplasma gondii Purine nucleoside phosphorylase 0.0089 0.0671 0.3064
Echinococcus granulosus histone deacetylase 7 0.0222 0.1941 0.1939
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0509 0.1187
Echinococcus multilocularis microtubule associated protein 2 0.0682 0.6324 0.6323
Schistosoma mansoni opsin-like receptor 0.0028 0.0087 0.0084
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0126 0.1026 0.2526
Brugia malayi exodeoxyribonuclease III family protein 0.008 0.0584 0.058
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0584 0.2662
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0043 0.0237 0.0234
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.008 0.0584 0.1393
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0087 0.0082
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0292 0.2608 0.2607
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0087 0.0082
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0144 0.0141
Echinococcus granulosus histone acetyltransferase MYST2 0.0122 0.0983 0.098
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0026 0.0068 0.0065
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0259 0.0256
Brugia malayi histone deacetylase 11 0.0106 0.0835 0.0831
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0087 0.0084
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0089 0.0671 0.0667
Trypanosoma cruzi histone deacetylase 1, putative 0.0247 0.2174 0.2172
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0087 0.0084
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0429 0.3912 0.3913
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0043 0.0237 0.0234
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0177 0.1515 0.1512
Echinococcus granulosus biogenic amine 5HT receptor 0.0145 0.1207 0.1205
Mycobacterium tuberculosis Conserved protein 0.0072 0.0509 0.1213
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Onchocerca volvulus 0.0042 0.0227 0.0352
Schistosoma mansoni biogenic amine receptor 0.0028 0.0087 0.0084
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.008 0.0584 0.1493
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0019 0.0007 0.0009
Schistosoma mansoni hypothetical protein 0.0106 0.0835 0.0832
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0025 0.0019
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0007 0.0004
Echinococcus granulosus thymidylate synthase 0.0126 0.1026 0.1023
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0147 0.1227 0.1223
Echinococcus multilocularis dihydrofolate reductase 0.0051 0.0314 0.0312
Echinococcus multilocularis transfer RNA-Lys 0.0042 0.0227 0.0224
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0034 0.0144 0.0139
Mycobacterium ulcerans endonuclease IV 0.009 0.0681 0.1742
Chlamydia trachomatis endonuclease IV 0.009 0.0681 0.9752
Schistosoma mansoni survival motor neuron protein 0.0151 0.1261 0.1258
Echinococcus granulosus methylthioadenosine phosphorylase 0.0089 0.0671 0.0668
Loa Loa (eye worm) hypothetical protein 0.0129 0.1052 0.1048
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis polycomb protein SCMH1 0.0107 0.0842 0.0839
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0126 0.1026 0.1023
Schistosoma mansoni DNA helicase recq1 0.0043 0.0237 0.0234
Brugia malayi cytoplasmic intermediate filament protein 0.0048 0.0283 0.0278
Loa Loa (eye worm) hypothetical protein 0.0025 0.0063 0.0057
Echinococcus granulosus histone deacetylase 8 0.0106 0.0835 0.0832
Trypanosoma cruzi histone deacetylase 1, putative 0.0247 0.2174 0.2172
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.005 0.0128
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0485 0.4445 0.4447
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0086
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0692 0.0689
Echinococcus granulosus orexin receptor type 2 0.0028 0.0087 0.0084
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0144 0.0141
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0259 0.0254
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0107 0.0842 0.0839
Echinococcus granulosus dihydrofolate reductase 0.0051 0.0314 0.0312
Giardia lamblia UPL-1 0.0089 0.0671 0.1704
Schistosoma mansoni ets-related 0.0217 0.1895 0.1893
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0259 0.0254
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.2667 0.2666
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0087 0.0084
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 1
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0087 0.0082
Onchocerca volvulus 0.0028 0.0087 0.0073
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0507 0.0502
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) RecQ helicase 0.0072 0.0514 0.051
Loa Loa (eye worm) histone deacetylase 0.0222 0.1941 0.1939
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.0499 0.0496
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0021 0.0027 0.009
Mycobacterium ulcerans beta-lactamase 0.0072 0.0509 0.13
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0437 0.3986 0.3984
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0429 0.3912 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0087 0.0084
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0018 0.0015
Giardia lamblia Sgs1 DNA helicase, putative 0.0043 0.0237 0.0593
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0509 0.0991
Trypanosoma cruzi trypanothione reductase, putative 0.011 0.0871 0.0867
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0087 0.0084
Trichomonas vaginalis DNA helicase recq1, putative 0.0072 0.0514 0.1003
Leishmania major trypanothione reductase 0.011 0.0871 0.0867
Plasmodium falciparum importin beta, putative 0.0028 0.0091 0.0386
Mycobacterium ulcerans hypothetical protein 0.0024 0.005 0.0128
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0007 0.0002
Brugia malayi Ets-domain containing protein 0.0072 0.0507 0.0502
Loa Loa (eye worm) histone deacetylase 1 0.0247 0.2174 0.2172
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0087 0.0084
Trichomonas vaginalis set domain proteins, putative 0.0552 0.5081 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0177 0.1507 0.1505
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0091 0.0386
Loa Loa (eye worm) hypothetical protein 0.1067 0.9989 1
Echinococcus multilocularis glutamate receptor NMDA 0.0076 0.055 0.0547
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0509 0.1213
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0584 0.114
Schistosoma mansoni tar DNA-binding protein 0.0133 0.1094 0.1091
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0429 0.3912 0.7675
Schistosoma mansoni single-minded 0.0057 0.0368 0.0366
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0089 0.0671 0.1704
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0259 0.0256
Schistosoma mansoni aryl hydrocarbon receptor 0.0057 0.0368 0.0366
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.0188 0.0182
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0499 0.0496
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0019 0.0007 0.0004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0087 0.0084
Trypanosoma brucei carbonic anhydrase-like protein 0.0147 0.1227 0.1223
Loa Loa (eye worm) TAR-binding protein 0.0133 0.1094 0.109
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.1227 0.1224
Brugia malayi Histone deacetylase family protein 0.0222 0.1941 0.1939
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0087 0.0084
Echinococcus granulosus survival motor neuron protein 1 0.0739 0.6864 0.6863
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.006 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0509 0.0991
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0087 0.0084
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0509 0.1213
Loa Loa (eye worm) mbt repeat family protein 0.0107 0.0842 0.0838
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0092 0.0699 0.3191
Echinococcus granulosus polycomb protein SCMH1 0.0107 0.0842 0.0839
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0292 0.0287
Brugia malayi Intermediate filament tail domain containing protein 0.009 0.0679 0.0675
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.008 0.0584 0.058
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.0188 0.0182
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0122 0.0983 0.098
Onchocerca volvulus 0.0028 0.0087 0.0073
Loa Loa (eye worm) hypothetical protein 0.0145 0.1207 0.1204
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Mycobacterium tuberculosis Hypothetical protein 0.0089 0.0671 0.1601
Brugia malayi PAS domain containing protein 0.0057 0.0368 0.0364
Echinococcus granulosus zinc finger protein 0.0027 0.0082 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Brugia malayi hypothetical protein 0.0192 0.1649 0.1646
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0041 0.0038
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0087 0.0084
Schistosoma mansoni importin beta-1 0.0028 0.0091 0.0088
Schistosoma mansoni blooms syndrome DNA helicase 0.005 0.0304 0.0301
Trypanosoma brucei trypanothione reductase 0.011 0.0871 0.0867
Brugia malayi AKH receptor 0.0028 0.0087 0.0082
Mycobacterium tuberculosis Conserved protein 0.0072 0.0509 0.1213
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0509 0.0504
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0453 0.0451
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0018 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.1133 0.113
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0087 0.0084
Plasmodium vivax histone deacetylase, putative 0.0222 0.1941 0.8927
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0765 0.0762
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0087 0.0084
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 1
Schistosoma mansoni hypothetical protein 0.1068 1 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0018 0.0015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0765 0.0762
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0089 0.0671 0.9606
Brugia malayi ORL1-like opioid receptor 0.0028 0.0087 0.0082
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0453 0.1159
Echinococcus granulosus fmrfamide receptor 0.0028 0.0087 0.0084
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0043 0.0237 0.0234
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0259 0.0254
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.0188 0.2684
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0144 0.0139
Brugia malayi GnHR receptor homolog 0.0028 0.0087 0.0082
Brugia malayi CXXC zinc finger family protein 0.0065 0.0444 0.044
Plasmodium falciparum glutathione reductase 0.0038 0.0188 0.0831
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0292 0.0287
Chlamydia trachomatis AMP nucleosidase 0.0089 0.0671 0.9606
Entamoeba histolytica exodeoxyribonuclease III, putative 0.008 0.0584 0.2669
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0058 0.0053
Brugia malayi Bloom's syndrome protein homolog 0.0072 0.0514 0.051
Loa Loa (eye worm) hypothetical protein 0.0048 0.0286 0.0281
Trypanosoma cruzi histone deacetylase, putative 0.0222 0.1941 0.1939
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0087 0.0084
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0115 0.0112
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0453 0.0449
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0007 0.0002
Echinococcus multilocularis cpg binding protein 0.0071 0.0501 0.0498
Mycobacterium tuberculosis Conserved hypothetical protein 0.0089 0.0671 0.1601
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0087 0.0082
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0092 0.0699 0.3191
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0019 0.0007 0.0004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0092 0.0699 0.0696
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni cpg binding protein 0.0071 0.0501 0.0498
Brugia malayi hypothetical protein 0.0143 0.1185 0.1182
Toxoplasma gondii endonuclease IV APN 0.009 0.0681 0.3111
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0066 0.0457 0.2075
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0509 0.2313
Schistosoma mansoni purine nucleoside phosphorylase 0.0429 0.3912 0.391
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0188 0.0182
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0287
Plasmodium vivax importin-beta 2, putative 0.0028 0.0091 0.0386
Schistosoma mansoni histamine h1 receptor 0.0028 0.0087 0.0084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0765 0.0762
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0182
Schistosoma mansoni adenoreceptor 0.0028 0.0087 0.0084
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0087 0.0084
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0107 0.0842 0.1573
Schistosoma mansoni neuropeptide receptor 0.0028 0.0087 0.0084
Onchocerca volvulus 0.0028 0.0087 0.0073
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0041 0.0035
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0259 0.0256
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0071 0.0499 0.0496
Schistosoma mansoni biogenic amine receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Loa Loa (eye worm) hypothetical protein 0.0034 0.0144 0.0139
Mycobacterium ulcerans thymidylate synthase 0.0126 0.1026 0.2622
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Brugia malayi PHD-finger family protein 0.0033 0.0142 0.0137
Mycobacterium tuberculosis Conserved protein 0.0072 0.0509 0.1213
Treponema pallidum pfs protein (pfs) 0.0089 0.0671 0.9606
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0063 0.0057
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0177 0.1515 0.696
Echinococcus granulosus hypothetical protein 0.0028 0.0087 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0087 0.0084
Brugia malayi Melatonin receptor type 1A 0.0028 0.0087 0.0082
Plasmodium falciparum carbonic anhydrase 0.0034 0.0144 0.0633
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0048 0.0283 0.0278
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0231 0.0228
Entamoeba histolytica hypothetical protein 0.0035 0.0161 0.0718
Brugia malayi Pre-SET motif family protein 0.0485 0.4445 0.4447
Schistosoma mansoni microtubule-associated protein tau 0.0682 0.6324 0.6323
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.008 0.0584 0.7758
Onchocerca volvulus 0.0028 0.0087 0.0073
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0007 0.0002
Mycobacterium ulcerans lipase LipD 0.0072 0.0509 0.13
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0259 0.0256
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0161 0.0158
Mycobacterium ulcerans hypothetical protein 0.0072 0.0509 0.13
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0259 0.0256
Onchocerca volvulus 0.0028 0.0087 0.0073
Mycobacterium leprae probable uridine phosphorylase 0.0089 0.0671 0.1608
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0177 0.1515 0.696
Loa Loa (eye worm) uridine phosphorylase 0.0089 0.0671 0.0667
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.0091 0.0086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0087 0.0084
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Trypanosoma cruzi histone deacetylase, putative 0.0106 0.0835 0.0831
Echinococcus multilocularis lamin dm0 0.009 0.0679 0.0676
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0237 0.0232
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0259 0.0254
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.1227 0.1223
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0087 0.0084
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0019 0.0007 0.0004
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0509 0.1213
Leishmania major histone deacetylase, putative 0.0247 0.2174 0.2172
Plasmodium vivax histone deacetylase 1, putative 0.0247 0.2174 1
Schistosoma mansoni lamin 0.009 0.0679 0.0676
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0141 0.1163 0.116
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.005 0.012
Onchocerca volvulus 0.009 0.0679 0.125
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0087 0.0084
Echinococcus granulosus g protein coupled receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.008 0.0584 0.0581
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0051 0.0314 0.075
Echinococcus granulosus dnaJ subfamily B 0.048 0.4396 0.4394
Schistosoma mansoni uridine phosphorylase 0.0089 0.0671 0.0668
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0237 0.0232
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0237 0.106
Chlamydia trachomatis dihydrofolate reductase 0.0051 0.0314 0.4501
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Mycobacterium tuberculosis Probable dehydrogenase 0.0251 0.2212 0.5276
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Onchocerca volvulus 0.0028 0.0087 0.0073
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3071
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0061 0.0408 0.0403
Schistosoma mansoni hypothetical protein 0.0034 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0046 0.0259 0.0254
Onchocerca volvulus 0.0065 0.0444 0.0783
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0005 0.0002
Brugia malayi TAR-binding protein 0.0133 0.1094 0.109
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Plasmodium vivax thioredoxin reductase, putative 0.011 0.0871 0.3988
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0087 0.0084
Echinococcus granulosus dna polymerase eta 0.0019 0.0005 0.0002
Schistosoma mansoni myosin xvIII 0.0028 0.0087 0.0084
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0087 0.0082
Echinococcus granulosus histone deacetylase 6 0.0222 0.1941 0.1939
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0087 0.0082
Leishmania major hypothetical protein, conserved 0.0025 0.0063 0.0057
Echinococcus multilocularis bloom syndrome protein 0.0072 0.0514 0.0511
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0063 0.0255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0041 0.0038
Schistosoma mansoni amine GPCR 0.0028 0.0087 0.0084
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.1133 0.113
Loa Loa (eye worm) hypothetical protein 0.0051 0.0312 0.0307
Leishmania major hypothetical protein, conserved 0.0072 0.0509 0.0504
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0019 0.0007 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0087 0.0084
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0092 0.0699 0.3191
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0509 0.13
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391
Plasmodium vivax glutathione reductase, putative 0.011 0.0871 0.3988
Loa Loa (eye worm) hypothetical protein 0.0042 0.0222 0.0217
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0063 0.0255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Entamoeba histolytica hypothetical protein 0.0035 0.0161 0.0718
Echinococcus granulosus single minded 2 0.0042 0.0227 0.0224
Echinococcus granulosus nmda type glutamate receptor 0.0102 0.0794 0.0791
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus histone deacetylase 3 0.0247 0.2174 0.2171
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0087 0.0084
Echinococcus granulosus peptidase Clp S14 family 0.006 0.0398 0.0395
Plasmodium vivax histone deacetylase 2, putative 0.0222 0.1941 0.8927
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0007 0.0002
Brugia malayi G protein-coupled receptor 0.0028 0.0087 0.0082
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.0188 0.0831
Leishmania major methylthioadenosine phosphorylase, putative 0.0089 0.0671 0.0667
Onchocerca volvulus 0.0028 0.0087 0.0073
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.0188 0.0479
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2174 0.4272
Leishmania major C-8 sterol isomerase-like protein 0.1067 0.9989 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0087 0.0084
Brugia malayi Serotonin receptor 0.0028 0.0087 0.0082
Echinococcus multilocularis histone deacetylase 3 0.0247 0.2174 0.2171
Echinococcus multilocularis geminin 0.1068 1 1
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0259 0.0256
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0115 0.0112
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0509 0.0504
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0041 0.007
Brugia malayi Bromodomain containing protein 0.0093 0.0709 0.0705
Brugia malayi hypothetical protein 0.0035 0.0161 0.0156
Echinococcus granulosus bloom syndrome protein 0.0072 0.0514 0.0511
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0144 0.0139
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0041 0.007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0144 0.0141
Brugia malayi Histone deacetylase family protein 0.0222 0.1941 0.1939
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0087 0.0084
Mycobacterium leprae Probable lipase LipE 0.0072 0.0509 0.1187
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) histone deacetylase 11 0.0106 0.0835 0.0831
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0035 0.0127
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.0188 0.0359
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Onchocerca volvulus 0.0028 0.0087 0.0073
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0089 0.0671 0.0667
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0584 0.2662
Schistosoma mansoni ap endonuclease 0.008 0.0584 0.0581
Plasmodium falciparum histone deacetylase 1 0.0247 0.2174 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0842 0.0838
Treponema pallidum exodeoxyribonuclease (exoA) 0.008 0.0584 0.836
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0087 0.0084
Onchocerca volvulus 0.0107 0.0842 0.1573
Schistosoma mansoni glutamate receptor NMDA 0.0087 0.0654 0.0651
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0251 0.2212 0.5276
Brugia malayi larval opioid receptor 0.0028 0.0087 0.0082
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0089 0.0671 0.0667
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0019 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Giardia lamblia Hypothetical protein 0.0019 0.0007 0.0005
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Echinococcus granulosus histone deacetylase 6 0.0235 0.2062 0.206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0007 0.0004
Loa Loa (eye worm) histone deacetylase 3 0.0247 0.2174 0.2172
Brugia malayi beta-lactamase family protein 0.0072 0.0509 0.0504
Loa Loa (eye worm) hypothetical protein 0.0043 0.0237 0.0232
Echinococcus granulosus lamin dm0 0.009 0.0679 0.0676
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Leishmania major histone deacetylase, putative 0.0247 0.2174 0.2172
Toxoplasma gondii histone deacetylase HDAC5 0.0106 0.0836 0.3826
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0292 0.0289
Echinococcus granulosus cpg binding protein 0.0071 0.0501 0.0498
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0796 0.7406 0.7405
Brugia malayi follicle stimulating hormone receptor 0.0292 0.2608 0.2607
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.009 0.0681 0.1625
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1067 0.9989 1
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0089 0.0671 0.1716
Loa Loa (eye worm) hypothetical protein 0.0046 0.0259 0.0254
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.008 0.0584 0.058
Schistosoma mansoni zinc finger protein 0.0027 0.0082 0.0079
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0043 0.0237 0.0232
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0087 0.0084
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0087 0.0084
Trypanosoma brucei C-8 sterol isomerase, putative 0.1067 0.9989 1
Brugia malayi hypothetical protein 0.0025 0.0063 0.0057
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis histone acetyltransferase MYST2 0.0122 0.0983 0.098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0116 0.0931 0.0927
Echinococcus granulosus GPCR family 2 0.0049 0.0292 0.0289
Giardia lamblia Histone deacetylase 0.0247 0.2174 0.555
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Toxoplasma gondii ABC1 family protein 0.0072 0.0509 0.2313
Schistosoma mansoni histone deacetylase 4 5 0.0222 0.1941 0.1939
Loa Loa (eye worm) hypothetical protein 0.0054 0.0343 0.0338
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0087 0.0084
Echinococcus granulosus SAM and MBT domain containing protein 0.0107 0.0842 0.0839
Echinococcus multilocularis histone deacetylase 0.0222 0.1941 0.1939
Echinococcus granulosus sex peptide receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis musashi 0.009 0.0679 0.0676
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Trypanosoma cruzi histone deacetylase, putative 0.0222 0.1941 0.1939
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Schistosoma mansoni tar DNA-binding protein 0.0133 0.1094 0.1091
Schistosoma mansoni methylthioadenosine phosphorylase 0.0089 0.0671 0.0668
Trypanosoma cruzi histone deacetylase, putative 0.0106 0.0835 0.0831
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus multilocularis snurportin 1 0.0298 0.2667 0.2665
Loa Loa (eye worm) hypothetical protein 0.0034 0.0144 0.0139
Trypanosoma brucei uridine phosphorylase 0.0089 0.0671 0.0667
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0087 0.0084
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 0.1786
Loa Loa (eye worm) carbonic anhydrase 3 0.0147 0.1227 0.1223
Entamoeba histolytica recQ family helicase, putative 0.0049 0.0294 0.1333
Brugia malayi uridine phosphorylase family protein 0.0089 0.0671 0.0667
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0177 0.1515 0.1512
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0032 0.0126 0.0547
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.009 0.0681 0.1635
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0185
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0089 0.0671 0.0668
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0294 0.0289
Loa Loa (eye worm) dihydrofolate reductase 0.0051 0.0314 0.031
Loa Loa (eye worm) hypothetical protein 0.0247 0.2174 0.2172
Echinococcus multilocularis thymidylate synthase 0.0126 0.1026 0.1023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0087 0.0084
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0043 0.0237 0.106
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0043 0.0237 0.0234
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0087 0.0082
Leishmania major carbonic anhydrase-like protein 0.0147 0.1227 0.1223
Echinococcus granulosus neuropeptide s receptor 0.0518 0.4763 0.4761
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0007 0.0002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0292 0.0289
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.008 0.0584 0.0581
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0259 0.117
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0509 0.0504
Echinococcus granulosus carbonic anhydrase II 0.0147 0.1227 0.1224
Schistosoma mansoni hypothetical protein 0.0028 0.0087 0.0084
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0019 0.0007 0.0004
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1067 0.9989 1
Schistosoma mansoni amine GPCR 0.0028 0.0087 0.0084
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0133 0.1094 0.1091
Onchocerca volvulus 0.0151 0.1261 0.2406
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0188 0.0182
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Brugia malayi G-protein coupled receptor 0.0028 0.0087 0.0082
Brugia malayi Serotonin receptor 0.0028 0.0087 0.0082
Brugia malayi RNA binding protein 0.0133 0.1094 0.109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0089 0.0671 0.1704
Echinococcus granulosus histone deacetylase 1 0.0247 0.2174 0.2171
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0087 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Echinococcus multilocularis SAM and MBT domain containing protein 0.0107 0.0842 0.0839
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0648 0.0645
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.006 0.0396 0.0391
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0161 0.0158
Echinococcus granulosus nmda type glutamate receptor 0.008 0.0585 0.0583
Onchocerca volvulus 0.0071 0.0499 0.0892
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0509 0.1213
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0041 0.007
Brugia malayi neuropeptide F receptor 0.0028 0.0087 0.0082
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.0188 0.0359
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0087 0.0073
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0765 0.0762
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0087 0.0084
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0092 0.0699 0.0696
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0087 0.0084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0765 0.0762
Onchocerca volvulus 0.0028 0.0087 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Loa Loa (eye worm) RNA binding protein 0.0133 0.1094 0.109
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0089 0.0671 0.0667
Loa Loa (eye worm) thymidylate synthase 0.0126 0.1026 0.1022
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0122 0.0983 0.0979
Toxoplasma gondii phosphorylase family protein 0.0089 0.0671 0.3064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0429 0.3912 0.7697
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0019 0.0007 0.0004
Schistosoma mansoni bromodomain containing protein 0.0079 0.0576 0.0573
Schistosoma mansoni cpg binding protein 0.0065 0.0444 0.0441
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0087 0.0084
Plasmodium falciparum glutathione reductase 0.011 0.0871 0.3988
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0765 0.0761
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0071 0.0499 0.227
Echinococcus granulosus carbonic anhydrase 0.0034 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.009 0.0679 0.0675
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.0188 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.1302 0.1299
Brugia malayi intermediate filament protein 0.009 0.0679 0.0675
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0507 0.0504
Brugia malayi mbt repeat family protein 0.0107 0.0842 0.0838
Mycobacterium ulcerans putative regulatory protein 0.0042 0.0227 0.0581
Loa Loa (eye worm) hypothetical protein 0.0034 0.0144 0.0139
Loa Loa (eye worm) fli-1 protein 0.0217 0.1895 0.1893
Schistosoma mansoni neuropeptide receptor 0.0028 0.0087 0.0084
Brugia malayi dihydrofolate reductase family protein 0.0051 0.0314 0.031
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0259 0.0256
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Leishmania major histone deacetylase, putative 0.0222 0.1941 0.1939
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0289
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0087 0.0084
Brugia malayi Probable ClpP-like protease 0.0092 0.0699 0.0695
Echinococcus granulosus g protein coupled receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis uridine phosphorylase 1 0.0089 0.0671 0.0668
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0087 0.0084
Brugia malayi Bromodomain containing protein 0.0046 0.0258 0.0253
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0087 0.0084
Schistosoma mansoni neuropeptide receptor 0.0028 0.0087 0.0084
Echinococcus granulosus dna polymerase kappa 0.0019 0.0005 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0087 0.0082
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0018 0.0015
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0453 0.0451
Echinococcus granulosus glutamate receptor NMDA 0.0076 0.055 0.0547
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0161 0.0158
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0509 0.0506
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0091 0.0088
Toxoplasma gondii histone deacetylase HDAC3 0.0247 0.2174 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2174 0.4272
Schistosoma mansoni histone deacetylase 4 5 0.0222 0.1941 0.1939
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Loa Loa (eye worm) hypothetical protein 0.0072 0.0509 0.0504
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.1227 0.1223
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0509 0.0506
Echinococcus granulosus carbonic anhydrase 0.0034 0.0144 0.0141
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0509 0.0506
Toxoplasma gondii histone deacetylase HDAC1 0.0222 0.1941 0.8927
Loa Loa (eye worm) hypothetical protein 0.0043 0.0237 0.0232
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0035 0.0032
Plasmodium falciparum thioredoxin reductase 0.0038 0.0188 0.0831
Loa Loa (eye worm) hypothetical protein 0.0192 0.1649 0.1646
Echinococcus multilocularis somatostatin receptor 0.0028 0.0087 0.0084
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0045 0.0255 0.1142
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0087 0.0084
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0092 0.0699 1
Toxoplasma gondii hypothetical protein 0.0034 0.0144 0.0633
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0453 0.0449
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0115 0.0112
Echinococcus multilocularis lamin 0.009 0.0679 0.0676
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0294 0.0289
Brugia malayi Ets-domain containing protein 0.0072 0.0507 0.0502
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0185
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0087 0.0082
Onchocerca volvulus Histone deacetylase 10 homolog 0.0106 0.0835 0.1559
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0259 0.05
Treponema pallidum NADH oxidase 0.0038 0.0188 0.2684
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0089 0.0671 0.0667
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0106 0.0835 0.0831
Echinococcus multilocularis serotonin receptor 0.0145 0.1207 0.1205
Loa Loa (eye worm) hypothetical protein 0.0739 0.6864 0.687
Schistosoma mansoni uridine phosphorylase 0.0089 0.0671 0.0668
Schistosoma mansoni biogenic amine (5HT) receptor 0.0145 0.1207 0.1205
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0126 0.1026 0.2446
Echinococcus granulosus lamin 0.009 0.0679 0.0676
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.003
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0087 0.0082
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0289
Echinococcus granulosus histone deacetylase 6 0.0222 0.1941 0.1939
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0279 0.2479 0.6288
Brugia malayi putative neuropeptide receptor 0.0028 0.0087 0.0082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0087 0.0084
Toxoplasma gondii histone deacetylase HDAC2 0.0247 0.2174 1
Leishmania major histone deacetylase, putative 0.0222 0.1941 0.1939
Echinococcus granulosus g protein coupled receptor 0.0028 0.0087 0.0084
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0063 0.0255
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Brugia malayi hypothetical protein 0.006 0.0396 0.0391
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.009 0.0681 0.0677
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus neuropeptide receptor 0.0028 0.0087 0.0084
Echinococcus granulosus purine nucleoside phosphorylase 0.0429 0.3912 0.391
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus granulosus uridine phosphorylase 1 0.0089 0.0671 0.0668
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0692 0.0689
Brugia malayi bHLH-PAS transcription factor 0.0042 0.0227 0.0222
Schistosoma mansoni dihydrofolate reductase 0.0051 0.0314 0.0312
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0144 0.0141
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.008 0.0584 0.058
Echinococcus granulosus tar DNA binding protein 0.0133 0.1094 0.1091
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0084 0.0625 0.0621
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0042 0.0222 0.0217
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0292 0.0289
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0429 0.3912 0.933
Echinococcus multilocularis histone deacetylase 6 0.0222 0.1941 0.1939
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0087 0.0084
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0041 0.0035
Schistosoma mansoni gabp alpha 0.0072 0.0507 0.0504
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.008 0.0584 0.058
Loa Loa (eye worm) beta-lactamase 0.0072 0.0509 0.0504
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0177 0.1515 0.1512
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0087 0.0084
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0043 0.0237 0.0234
Brugia malayi Dihydrofolate reductase 0.0051 0.0314 0.031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0032 0.0126 0.0196
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0019 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0087 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0019 0.0007 0.0004
Onchocerca volvulus 0.0028 0.0087 0.0073
Brugia malayi G-protein coupled receptor 0.0028 0.0087 0.0082
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0144 0.0141
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.0188 0.0447
Echinococcus granulosus somatostatin receptor 0.0028 0.0087 0.0084
Schistosoma mansoni cpg binding protein 0.0071 0.0501 0.0498
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0294 0.0289
Schistosoma mansoni hypothetical protein 0.0151 0.1261 0.1258
Schistosoma mansoni hypothetical protein 0.0298 0.2667 0.2665
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0259 0.065
Onchocerca volvulus 0.0072 0.0509 0.0911
Loa Loa (eye worm) histone deacetylase 7A 0.0222 0.1941 0.1939
Plasmodium falciparum histone deacetylase, putative 0.0222 0.1941 0.8927
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.1261 0.1257
Leishmania major importin beta-1 subunit, putative 0.0023 0.0041 0.0035
Echinococcus multilocularis nmda type glutamate receptor 0.0102 0.0794 0.0791
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.005 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Echinococcus multilocularis dnaJ subfamily B 0.048 0.4396 0.4394
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.1227 0.1224
Brugia malayi sulfakinin receptor protein 0.0028 0.0087 0.0082
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0044 0.0247 0.1105
Echinococcus multilocularis serotonin receptor 0.0145 0.1207 0.1205
Brugia malayi hypothetical protein 0.0739 0.6864 0.687
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0144 0.0139
Onchocerca volvulus 0.0072 0.0509 0.0911
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0087 0.0084
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.0188 0.0479
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0292 0.0289
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0087 0.0084
Brugia malayi neuropeptide F receptor 0.0028 0.0087 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0396 0.077
Schistosoma mansoni neuropeptide receptor 0.0028 0.0087 0.0084
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0089 0.0671 0.0667
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0188 0.0182
Schistosoma mansoni hypothetical protein 0.0028 0.0087 0.0084
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0411 0.0406
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0692 0.0689
Echinococcus multilocularis neuropeptide s receptor 0.0518 0.4763 0.4761
Loa Loa (eye worm) intermediate filament protein 0.009 0.0679 0.0675
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0087 0.0084
Echinococcus granulosus histone deacetylase 0.0222 0.1941 0.1939
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0509 0.1213
Echinococcus multilocularis thioredoxin glutathione reductase 0.011 0.0871 0.0869
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0043 0.0237 0.0234
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0509 0.0991
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0692 0.0689
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3064
Echinococcus multilocularis carbonic anhydrase II 0.0147 0.1227 0.1224
Onchocerca volvulus 0.0028 0.0087 0.0073
Loa Loa (eye worm) hypothetical protein 0.0091 0.0692 0.0688
Schistosoma mansoni sex comb on midleg homolog 0.0107 0.0842 0.0839
Schistosoma mansoni amine GPCR 0.0028 0.0087 0.0084
Schistosoma mansoni hypothetical protein 0.0035 0.0161 0.0158
Brugia malayi glutathione reductase 0.011 0.0871 0.0867
Brugia malayi Fli-1 protein 0.0217 0.1895 0.1893
Toxoplasma gondii exonuclease III APE 0.008 0.0584 0.2662
Echinococcus multilocularis purine nucleoside phosphorylase 0.034 0.3066 0.3064
Schistosoma mansoni methylthioadenosine phosphorylase 0.0089 0.0671 0.0668
Loa Loa (eye worm) hypothetical protein 0.034 0.3066 0.3066
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0087 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0087 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0032 0.0126 0.0547
Echinococcus multilocularis histone deacetylase 7 0.0222 0.1941 0.1939
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0087 0.0084
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0765 0.0761
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0509 0.1213
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.0188 0.0831
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0453 0.0451
Brugia malayi thymidylate synthase 0.0126 0.1026 0.1022
Echinococcus multilocularis sex peptide receptor 0.0028 0.0087 0.0084
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0067 0.0461 0.0458
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.1094 0.109
Echinococcus multilocularis tar DNA binding protein 0.0133 0.1094 0.1091
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0091 0.0086
Onchocerca volvulus 0.0028 0.0087 0.0073
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.1094 0.109
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0509 0.0991
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0147 0.1227 0.1223
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0279 0.2479 0.5911
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0087 0.0084
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0459 0.4193 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0536 0.0533
Schistosoma mansoni opsin-like receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis survival motor neuron protein 1 0.0739 0.6864 0.6863
Schistosoma mansoni histone deacetylase hda2 0.0235 0.2062 0.206
Trypanosoma brucei histone deacetylase, putative 0.0222 0.1941 0.1939
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0087 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0133 0.1094 0.1091
Echinococcus multilocularis neuropeptide receptor A26 0.0518 0.4763 0.4761
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0087 0.0084
Echinococcus multilocularis dna polymerase eta 0.0019 0.0005 0.0002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0237 0.106
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3071
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.0294 0.0569
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0453 0.1082
Loa Loa (eye worm) hypothetical protein 0.0088 0.0664 0.0659
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0835 0.0831
Schistosoma mansoni DNA helicase recq5 0.0043 0.0237 0.0234
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0063 0.0255
Echinococcus granulosus importin subunit beta 1 0.0028 0.0091 0.0088
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0089 0.0671 0.1312
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0835 0.0832
Schistosoma mansoni lamin 0.009 0.0679 0.0676
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0019 0.0007 0.0002
Onchocerca volvulus 0.0028 0.0087 0.0073
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Loa Loa (eye worm) hypothetical protein 0.0092 0.0699 0.0695
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0251 0.2212 0.5276
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0063 0.0057
Loa Loa (eye worm) MBCTL1 0.0122 0.0983 0.0979
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.006 0.0398 0.0948
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.034 0.3066 0.3064
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0509 0.0504
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.0188 0.0466
Plasmodium falciparum purine nucleoside phosphorylase 0.0089 0.0671 0.3064
Plasmodium falciparum histone deacetylase 2 0.0222 0.1941 0.8927
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0429 0.3912 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0259 0.05
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0444 0.044
Trypanosoma cruzi histone deacetylase, putative 0.0222 0.1941 0.1939
Entamoeba histolytica hypothetical protein 0.0035 0.0161 0.0718
Trypanosoma brucei histone deacetylase 3 0.0222 0.1941 0.1939
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0089 0.0671 0.3071
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.1302 0.1299
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0089 0.0671 0.1716
Loa Loa (eye worm) hypothetical protein 0.0106 0.0835 0.0831
Loa Loa (eye worm) hypothetical protein 0.0545 0.502 0.5023
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0087 0.0084
Trichomonas vaginalis esterase, putative 0.0072 0.0509 0.0991
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.0188 0.0831
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0005 0.0013
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0144 0.0139
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0122 0.0983 0.098
Echinococcus granulosus intermediate filament protein 0.009 0.0679 0.0676
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Brugia malayi MTAP 0.0089 0.0671 0.0667
Schistosoma mansoni myelin transcription factor 1 myt1 0.0122 0.0983 0.098
Brugia malayi hypothetical protein 0.0028 0.0087 0.0082
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0032 0.0126 0.1803
Echinococcus multilocularis histone deacetylase 6 0.0222 0.1941 0.1939
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0087 0.0084
Schistosoma mansoni amine GPCR 0.0028 0.0087 0.0084
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0019 0.0007 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0188 0.0182
Entamoeba histolytica hypothetical protein 0.0035 0.0161 0.0718
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0087 0.0084
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.0188 0.0831
Echinococcus granulosus serotonin receptor 0.0028 0.0087 0.0084
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0188 0.0182
Brugia malayi Dopamine receptor 0.0028 0.0087 0.0082
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0087 0.0082
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0087 0.0084
Brugia malayi hypoxia-induced factor 1 0.0177 0.1507 0.1505
Brugia malayi beta-lactamase family protein 0.0072 0.0509 0.0504
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0005 0.0002
Schistosoma mansoni purine nucleoside phosphorylase 0.0429 0.3912 0.391
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0177 0.1515 0.696
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0087 0.0082
Echinococcus granulosus snurportin 1 0.0298 0.2667 0.2665
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0292 0.0287
Brugia malayi Dopamine receptor protein 1 0.0028 0.0087 0.0082
Toxoplasma gondii phosphorylase family protein 0.0089 0.0671 0.3064
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Plasmodium vivax SET domain protein, putative 0.0071 0.0499 0.227
Echinococcus multilocularis peptidase Clp (S14 family) 0.006 0.0398 0.0395
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0051 0.0314 0.0804
Treponema pallidum uridine phosphorylase (udp) 0.0089 0.0671 0.9606
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0082
Echinococcus multilocularis histone deacetylase 1 0.0247 0.2174 0.2171
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0289
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2174 0.4272
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0019 0.0007 0.0009
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0289
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2174 0.4272
Brugia malayi histone deacetylase 3 (HD3) 0.0247 0.2174 0.2172
Mycobacterium tuberculosis Probable oxidoreductase 0.0279 0.2479 0.5911
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0089 0.0671 0.1601
Toxoplasma gondii histone lysine methyltransferase SET1 0.0129 0.105 0.4811
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0087 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0671 0.1312
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0536 0.0533
Brugia malayi Thioredoxin reductase 0.011 0.0871 0.0867
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0087 0.0084
Trypanosoma brucei histone deacetylase 1 0.0247 0.2174 0.2172
Plasmodium vivax histone deacetylase, putative 0.0106 0.0835 0.3819
Echinococcus multilocularis purine nucleoside phosphorylase 0.0429 0.3912 0.391

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.000000012 M Inhibition of human carbonic anhydrase II ChEMBL. 1433194

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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