Detailed information for compound 1036559

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 260.762 | Formula: C15H17ClN2
  • H donors: 1 H acceptors: 0 LogP: 3.23 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1c(ccc2c1cccc2)CC1=NCCN1.Cl
  • InChi: 1S/C15H16N2.ClH/c1-11-13(10-15-16-8-9-17-15)7-6-12-4-2-3-5-14(11)12;/h2-7H,8-10H2,1H3,(H,16,17);1H
  • InChiKey: YNSVEKIFSKPRMF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Adrenergic receptor alpha-2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis serotonin receptor Adrenergic receptor alpha-2   450 aa 426 aa 31.9 %
Loa Loa (eye worm) TYRA-2 protein Adrenergic receptor alpha-2   450 aa 488 aa 23.8 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Adrenergic receptor alpha-2   450 aa 473 aa 24.1 %
Echinococcus granulosus alpha 1A adrenergic receptor Adrenergic receptor alpha-2   450 aa 476 aa 21.0 %
Echinococcus multilocularis fmrfamide receptor Adrenergic receptor alpha-2   450 aa 366 aa 19.9 %
Echinococcus granulosus biogenic amine 5HT receptor Adrenergic receptor alpha-2   450 aa 423 aa 31.7 %
Echinococcus multilocularis alpha 1A adrenergic receptor Adrenergic receptor alpha-2   450 aa 478 aa 20.7 %
Onchocerca volvulus Adrenergic receptor alpha-2   450 aa 467 aa 25.1 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Adrenergic receptor alpha-2   450 aa 378 aa 20.9 %
Schistosoma mansoni amine GPCR Adrenergic receptor alpha-2   450 aa 439 aa 29.2 %
Onchocerca volvulus Adrenergic receptor alpha-2   450 aa 420 aa 19.8 %
Echinococcus multilocularis neuropeptides capa receptor Adrenergic receptor alpha-2   450 aa 486 aa 20.6 %
Schistosoma mansoni biogenic amine (5HT) receptor Adrenergic receptor alpha-2   450 aa 433 aa 27.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0106 0.0494 0.0494
Entamoeba histolytica protein kinase domain containing protein 0.0106 0.049 0.1807
Onchocerca volvulus 0.0072 0.0248 0.0511
Brugia malayi Protein kinase domain containing protein 0.0043 0.004 0.004
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0247 0.1508 0.2193
Echinococcus granulosus serine:threonine protein kinase N2 0.0068 0.0222 0.0268
Entamoeba histolytica protein kinase, putative 0.0083 0.0331 0.1221
Schistosoma mansoni vav2 0.0084 0.0337 0.07
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0216 0.128 0.128
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0106 0.049 0.1726
Brugia malayi Tyrosine-protein kinase abl-1 0.0152 0.0825 0.0825
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Leishmania major protein kinase A catalytic subunit isoform 2 0.0407 0.265 1
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Loa Loa (eye worm) hypothetical protein 0.009 0.0378 0.0378
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0308 0.1942 0.2825
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0263 0.1616 0.1616
Schistosoma mansoni protein kinase 0.0053 0.011 0.0228
Brugia malayi Variant SH3 domain containing protein 0.0063 0.0188 0.0188
Trypanosoma cruzi cdc2-related kinase 1 0.0128 0.0649 0.2378
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0057 0.014 0.0203
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0053 0.011 0.0326
Echinococcus multilocularis death associated protein kinase 1 0.0995 0.6875 1
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.011 0.0227
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0137 0.0715 0.104
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0308 0.1942 0.7303
Plasmodium falciparum calcium-dependent protein kinase 1 0.0053 0.011 0.0219
Echinococcus granulosus peroxidasin 0.0042 0.0033 0.004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Plasmodium vivax serine/threonine protein kinase 6, putative 0.016 0.0877 0.3209
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0031 0.0031
Echinococcus multilocularis cyclin dependent kinase 1 0.0128 0.0649 0.0945
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0074 0.0266 0.0266
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Plasmodium falciparum serine/threonine protein kinase KIN 0.0053 0.011 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0102 0.0212
Echinococcus granulosus mitogen activated protein kinase 11 0.0176 0.0993 0.1199
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0076 0.0276 0.0574
Schistosoma mansoni protein kinase 0.0039 0.0009 0.0019
Brugia malayi Protein kinase domain containing protein 0.0208 0.1222 0.1222
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0274 0.1697 0.1697
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Trypanosoma brucei Casein kinase II 0.0106 0.049 0.1682
Loa Loa (eye worm) hypothetical protein 0.009 0.038 0.038
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0059 0.0152 0.0382
Schistosoma mansoni titin 0.0048 0.008 0.0166
Entamoeba histolytica protein kinase, putative 0.0053 0.011 0.0406
Trypanosoma cruzi casein kinase, putative 0.0071 0.024 0.0817
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.016
Echinococcus granulosus tyrosine kinase 0.0142 0.0749 0.0904
Echinococcus multilocularis mitogen activated protein kinase 11 0.0176 0.0993 0.1445
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0225 0.1348 0.1627
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0089 0.037 0.0446
Echinococcus granulosus insulin receptor 0.0515 0.3431 0.414
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0042 0.0031 0.0065
Brugia malayi Protein kinase domain containing protein 0.0072 0.0248 0.0248
Echinococcus multilocularis mitogen activated protein kinase 3 0.0086 0.035 0.0509
Echinococcus multilocularis 0.0207 0.1214 0.1766
Loa Loa (eye worm) hypothetical protein 0.0088 0.0363 0.0363
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0331 0.107
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0087 0.0358 0.1321
Brugia malayi intracellular kinase 0.014 0.0734 0.0734
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0321 0.2034 0.2034
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Loa Loa (eye worm) hypothetical protein 0.0146 0.0782 0.0782
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0053 0.011 0.011
Plasmodium vivax protein kinase Crk2 0.0128 0.0649 0.2337
Leishmania major casein kinase II, putative 0.0106 0.049 0.177
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus multilocularis cyclin dependent kinase 0.0128 0.0649 0.0945
Toxoplasma gondii CMGC kinase, CK2 family 0.0106 0.049 0.1773
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Brugia malayi casein kinase I 0.0071 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0053 0.011 0.011
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.016 0.0877 0.3236
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0086 0.035 0.1241
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.035 0.1144
Giardia lamblia Kinase, NEK 0.0148 0.0797 0.2866
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.017 0.0952 0.1149
Entamoeba histolytica protein kinase, putative 0.016 0.0877 0.3236
Brugia malayi SRC-1 0.017 0.0952 0.0952
Loa Loa (eye worm) hypothetical protein 0.0122 0.0609 0.0609
Plasmodium vivax glycogen synthase kinase 3, putative 0.014 0.0734 0.2659
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0045 0.0052 0.0075
Schistosoma mansoni rac gtpase activating protein 0.0041 0.0024 0.0051
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0072 0.0248 0.0361
Echinococcus multilocularis casein kinase I alpha 0.0071 0.024 0.0349
Leishmania major protein kinase, putative 0.0057 0.014 0.0436
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Loa Loa (eye worm) hypothetical protein 0.0045 0.0052 0.0052
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0052 0.0102 0.0292
Echinococcus granulosus titin 0.0048 0.008 0.0097
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0072 0.0248 0.03
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0079 0.0299 0.0299
Echinococcus granulosus defective proboscis extension response 0.009 0.0378 0.0456
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.016
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0263 0.162 0.2357
Loa Loa (eye worm) AGC/PKG protein kinase 0.0057 0.014 0.014
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0051 0.0102 0.0123
Brugia malayi diacylglycerol kinase 0.0041 0.0024 0.0024
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0128 0.0649 0.0649
Echinococcus granulosus calcium activated potassium channel 0.0098 0.0439 0.0529
Echinococcus multilocularis c src tyrosine kinase 0.01 0.0452 0.0658
Trichomonas vaginalis CK1 family protein kinase 0.0071 0.024 0.0719
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0053 0.011 0.0321
Loa Loa (eye worm) hypothetical protein 0.0131 0.0673 0.0673
Echinococcus multilocularis twitchin 0.0046 0.006 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Trypanosoma brucei protein kinase, putative 0.014 0.0734 0.2621
Echinococcus granulosus nervana 2 0.0147 0.0788 0.0951
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0407 0.265 1
Brugia malayi MAP kinase sur-1 0.0086 0.035 0.035
Giardia lamblia Kinase, PLK 0.0308 0.1942 0.7274
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0128 0.0649 0.0649
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0301 0.1891 0.1891
Echinococcus multilocularis serine:threonine protein kinase 38 0.0174 0.0979 0.1424
Brugia malayi Egg laying defective protein 4 0.0057 0.014 0.014
Onchocerca volvulus 0.0146 0.0782 0.1765
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0053 0.011 0.0321
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0053 0.011 0.027
Echinococcus granulosus neuroglian 0.011 0.052 0.0628
Echinococcus multilocularis casein kinase I alpha 0.0071 0.024 0.0349
Schistosoma mansoni cell adhesion molecule 0.0115 0.0554 0.1151
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0292 0.1827 0.1827
Loa Loa (eye worm) hypothetical protein 0.0283 0.1761 0.1761
Schistosoma mansoni growth factor receptor-bound protein 0.0063 0.0188 0.039
Echinococcus granulosus netrin receptor unc 5 0.0039 0.0012 0.0014
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0247 0.1508 0.182
Echinococcus multilocularis Immunoglobulin 0.009 0.0378 0.0549
Echinococcus granulosus single minded 2 0.0043 0.0041 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.162 0.3363
Echinococcus granulosus cyclin dependent kinase 1 0.0128 0.0649 0.0784
Schistosoma mansoni neuroglian 0.0045 0.0052 0.0107
Echinococcus granulosus tyrosine protein kinase Src64B 0.017 0.0952 0.1149
Brugia malayi Protein kinase domain containing protein 0.0198 0.1153 0.1153
Entamoeba histolytica protein kinase, putative 0.014 0.0734 0.2706
Entamoeba histolytica hypothetical protein 0.0132 0.0679 0.2504
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Onchocerca volvulus 0.0048 0.008 0.0115
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0176 0.0993 0.3689
Loa Loa (eye worm) hypothetical protein 0.0047 0.0071 0.0071
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0057 0.014 0.0203
Echinococcus granulosus epidermal growth factor receptor 0.0461 0.3042 0.3671
Schistosoma mansoni lipoxygenase 0.0099 0.044 0.0913
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.0331 0.0331
Plasmodium falciparum casein kinase 1 0.0071 0.024 0.0719
Echinococcus granulosus tyrosine protein kinase shark 0.0072 0.0249 0.0301
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0274 0.1697 0.2468
Echinococcus multilocularis survival motor neuron protein 1 0.0283 0.1761 0.2562
Trypanosoma brucei protein kinase, putative 0.0063 0.0181 0.0493
Loa Loa (eye worm) hypothetical protein 0.0171 0.0957 0.0957
Echinococcus multilocularis serine:threonine protein kinase N2 0.0174 0.0979 0.1424
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0132 0.0679 0.249
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0051 0.0102 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.024 0.0498
Brugia malayi Protein kinase domain containing protein 0.0072 0.0248 0.0248
Brugia malayi phosphoinositide-dependent protein kinase I 0.0083 0.0331 0.0331
Trichomonas vaginalis STE family protein kinase 0.0148 0.0797 0.2866
Loa Loa (eye worm) hypoxia-induced factor 1 0.018 0.1024 0.1024
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Brugia malayi protein unc-22 0.0048 0.008 0.008
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1431 1 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0308 0.1942 0.7303
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0053 0.011 0.0269
Onchocerca volvulus 0.0043 0.0041 0.0024
Brugia malayi Casein kinase II, alpha chain 0.0106 0.049 0.049
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0455 0.2999 0.2999
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0518 0.3451 0.502
Entamoeba histolytica PH domain containing protein kinase, putative 0.0181 0.1033 0.3811
Trypanosoma brucei cdc2-related kinase 1 0.0128 0.0649 0.2296
Loa Loa (eye worm) TK protein kinase 0.0292 0.1831 0.1831
Echinococcus granulosus casein kinase i 0.0071 0.024 0.0289
Echinococcus granulosus c-Jun N-terminal kinases 0.0301 0.1891 0.2282
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.017 0.0952 0.1149
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0052 0.0075
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0071 0.024 0.029
Echinococcus granulosus neuroglian 0.0045 0.0052 0.0063
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0176 0.0993 0.3689
Loa Loa (eye worm) AGC/AKT protein kinase 0.0329 0.2095 0.2095
Schistosoma mansoni protein kinase 0.0247 0.1508 0.313
Echinococcus granulosus tumor protein p63 0.0404 0.2632 0.3176
Trypanosoma cruzi casein kinase, putative 0.0071 0.024 0.0817
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0407 0.265 1
Schistosoma mansoni atypical protein kinase C 0.032 0.203 0.4214
Trichomonas vaginalis AGC family protein kinase 0.0407 0.265 1
Onchocerca volvulus 0.0042 0.0035 0.0009
Trichomonas vaginalis CK1 family protein kinase 0.0071 0.024 0.0719
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Schistosoma mansoni tyrosine kinase 0.017 0.0952 0.1977
Brugia malayi protein-tyrosine kinase 0.0142 0.0749 0.0749
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3854
Brugia malayi serine/threonine kinase 12 0.016 0.0877 0.0877
Echinococcus granulosus tyrosine protein kinase Fyn 0.017 0.0952 0.1149
Echinococcus multilocularis tyrosine protein kinase Srms 0.0142 0.0749 0.1089
Entamoeba histolytica protein kinase, putative 0.0089 0.037 0.1363
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.017 0.0952 0.1385
Echinococcus granulosus roundabout 2 0.0045 0.0052 0.0063
Loa Loa (eye worm) TK/EPH protein kinase 0.0134 0.0693 0.0693
Echinococcus granulosus cGMP dependent protein kinase 1 0.0057 0.014 0.0169
Trichomonas vaginalis STE family protein kinase 0.0087 0.0358 0.1174
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0076 0.0276 0.0276
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0649 0.2296
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0087 0.0358 0.1321
Echinococcus multilocularis epidermal growth factor receptor 0.0461 0.3042 0.4424
Schistosoma mansoni hypothetical protein 0.0073 0.0254 0.0527
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0089 0.037 0.0538
Echinococcus multilocularis dual specificity 0.0132 0.0679 0.0987
Brugia malayi C1-like domain containing protein 0.0163 0.0905 0.0905
Schistosoma mansoni lipoxygenase 0.0141 0.0744 0.1545
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0382 0.2472 0.9322
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0079 0.0299 0.062
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0105 0.0485 0.0705
Loa Loa (eye worm) AGC/PKA protein kinase 0.0407 0.265 0.265
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0071 0.024 0.0349
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0249 0.1518 0.1518
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0299 0.0946
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0045 0.0053 0.5
Echinococcus granulosus tyrosine protein kinase Srms 0.0072 0.0248 0.03
Entamoeba histolytica protein kinase, putative 0.0132 0.0679 0.2504
Echinococcus granulosus epidermal growth factor receptor 0.0709 0.4818 0.5814
Brugia malayi P38 map kinase family protein 2 0.0176 0.0993 0.0993
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0147 0.0788 0.1146
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0979 0.2032
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0053 0.011 0.0219
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0052 0.0102 0.0102
Giardia lamblia Kinase, NEK 0.0148 0.0797 0.2866
Loa Loa (eye worm) hypothetical protein 0.0097 0.0429 0.0429
Schistosoma mansoni tyrosine kinase 0.0424 0.2777 0.5765
Schistosoma mansoni adapter molecule crk 0.0063 0.0188 0.039
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0053 0.011 0.0321
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0052 0.0102 0.0102
Trypanosoma cruzi casein kinase II, putative 0.0106 0.049 0.177
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0979 0.2032
Onchocerca volvulus 0.0165 0.0917 0.2082
Entamoeba histolytica casein kinase, putative 0.0106 0.049 0.1807
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0045 0.0053 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Echinococcus granulosus Protein kinase C brain isozyme 0.0263 0.162 0.1955
Trichomonas vaginalis STE family protein kinase 0.0089 0.037 0.1219
Brugia malayi Protein kinase domain containing protein 0.0174 0.0979 0.0979
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0042 0.0035 0.0042
Giardia lamblia Kinase, CAMK CAMKL 0.0053 0.011 0.0217
Giardia lamblia Kinase, CMGC GSK 0.014 0.0734 0.2621
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0225 0.1348 0.1961
Echinococcus granulosus protein kinase shaggy 0.014 0.0734 0.0885
Echinococcus granulosus Diacylglycerol kinase theta 0.0041 0.0024 0.0029
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0098 0.0439 0.0439
Trypanosoma brucei aurora B kinase 0.016 0.0877 0.3173
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0052 0.0102 0.0102
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0172 0.0968 0.0968
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.0085
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0089 0.037 0.0446
Brugia malayi Protein kinase c protein 2 0.0115 0.0558 0.0558
Echinococcus granulosus serine:threonine protein kinase N2 0.0242 0.1469 0.1773
Echinococcus granulosus myotubularin protein 13 0.0049 0.0085 0.0103
Giardia lamblia Kinase, CMGC CDK 0.0128 0.0649 0.2296
Onchocerca volvulus 0.0059 0.0157 0.0295
Giardia lamblia Kinase, AGC PKA 0.0173 0.0972 0.3539
Leishmania major protein kinase, putative 0.0087 0.0358 0.1268
Schistosoma mansoni tyrosine kinase 0.0424 0.2777 0.5765
Loa Loa (eye worm) SRC-1 0.017 0.0952 0.0952
Loa Loa (eye worm) TK protein kinase 0.0107 0.0497 0.0497
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0259 0.159 0.2313
Schistosoma mansoni survival motor neuron protein 0.0058 0.0146 0.0303
Schistosoma mansoni vesicular amine transporter 0.009 0.0378 0.0784
Echinococcus multilocularis serine:threonine protein kinase 0.0122 0.0609 0.0886
Echinococcus multilocularis casein kinase ii subunit alpha 0.0106 0.049 0.0713
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.0133
Trichomonas vaginalis AGC family protein kinase 0.016 0.0877 0.3173
Schistosoma mansoni roundabout 0.0042 0.0031 0.0065
Echinococcus granulosus survival motor neuron protein 1 0.0283 0.1761 0.2126
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0173 0.0972 0.1414
Trichomonas vaginalis AGC family protein kinase 0.016 0.0877 0.3173
Onchocerca volvulus Serine\/threonine kinase homolog 0.0308 0.1942 0.4493
Schistosoma mansoni serine/threonine-protein kinase 0.0181 0.1033 0.2144
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Brugia malayi Protein kinase domain containing protein 0.0515 0.3431 0.3431
Onchocerca volvulus 0.0477 0.3158 0.7352
Echinococcus multilocularis cyclin dependent kinase 5 0.0128 0.0649 0.0945
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0045 0.0053 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.2999 0.6225
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.014 0.029
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0181 0.0593
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3854
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Brugia malayi probable protein kinase 0.0039 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Entamoeba histolytica protein kinase, putative 0.0132 0.0679 0.2504
Brugia malayi Kinase associated domain 1 family protein 0.0073 0.0254 0.0254
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0053 0.011 0.0326
Echinococcus granulosus serine:threonine protein kinase 0.0122 0.0609 0.0735
Onchocerca volvulus 0.0058 0.0146 0.027
Schistosoma mansoni hypothetical protein 0.0073 0.0254 0.0527
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0053 0.011 0.027
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0407 0.265 0.265
Schistosoma mansoni nck2/grb4 0.0063 0.0188 0.039
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0079 0.0299 0.0435
Echinococcus granulosus transcription factor Dp 1 0.0046 0.006 0.0073
Echinococcus granulosus ephrin type A receptor 4 A 0.0113 0.0543 0.0655
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0076 0.0276 0.0574
Schistosoma mansoni protein kinase 0.0106 0.049 0.1017
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0173 0.0972 0.3608
Echinococcus granulosus titin 0.0048 0.008 0.0097
Plasmodium vivax calcium-dependent protein kinase, putative 0.0053 0.011 0.027
Brugia malayi Pre-SET motif family protein 0.0249 0.1518 0.1518
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0045
Brugia malayi PAS domain containing protein 0.0058 0.015 0.015
Echinococcus granulosus serine:threonine kinase SAD 1 0.0053 0.011 0.0132
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0071 0.024 0.024
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0461 0.3042 0.3671
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0112 0.0534 0.0534
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0679 0.2504
Echinococcus granulosus hemicentin 1 0.0042 0.0031 0.0038
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0174 0.0979 0.1181
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis titin 0.0048 0.008 0.0117
Schistosoma mansoni protein kinase C mu 0.0041 0.0024 0.0051
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0206 0.1209 0.1209
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0053 0.011 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0468 0.0971
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0159 0.0871 0.1052
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0407 0.265 1
Trichomonas vaginalis set domain proteins, putative 0.0283 0.1765 0.6592
Trichomonas vaginalis AGC family protein kinase 0.0198 0.1153 0.4237
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3854
Plasmodium falciparum protein kinase 5 0.0128 0.0649 0.2296
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0128 0.0649 0.2378
Trypanosoma cruzi polo-like protein kinase, putative 0.0308 0.1942 0.7303
Echinococcus multilocularis protein kinase shaggy 0.014 0.0734 0.1067
Trichomonas vaginalis AGC family protein kinase 0.0198 0.1153 0.4237
Loa Loa (eye worm) hypothetical protein 0.0097 0.0429 0.0429
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0045 0.0053 0.011
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0797 0.2866
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0319 0.2018 0.2936
Brugia malayi Protein kinase domain containing protein 0.0132 0.0679 0.0679
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0173 0.0972 0.1173
Onchocerca volvulus 0.0097 0.0429 0.0935
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0045 0.0053 0.0053
Echinococcus multilocularis casein kinase i 0.0071 0.024 0.0349
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.014 0.0734 0.1067
Brugia malayi Protein kinase domain containing protein 0.0083 0.0331 0.0331
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.014 0.029
Echinococcus multilocularis myotubularin protein 13 0.0049 0.0085 0.0124
Trichomonas vaginalis STE family protein kinase 0.0089 0.037 0.1219
Brugia malayi Variant SH3 domain containing protein 0.0063 0.0188 0.0188
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0195 0.1131 0.1365
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.005 0.0091 0.0147
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0132 0.0679 0.0679
Entamoeba histolytica protein kinase, putative 0.0329 0.2095 0.7729
Plasmodium falciparum calcium-dependent protein kinase 2 0.0053 0.011 0.0219
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0734 0.2706
Echinococcus granulosus dual specificity 0.0132 0.0679 0.0819
Echinococcus multilocularis casein kinase I alpha 0.0071 0.024 0.0349
Trypanosoma brucei casein kinase I, isoform 2 0.0071 0.024 0.0719
Giardia lamblia Kinase, CAMK CAMKL 0.0053 0.011 0.0217
Toxoplasma gondii aurora kinase 0.016 0.0877 0.3248
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0134 0.0696 0.2554
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0132 0.0679 0.249
Entamoeba histolytica tyrosin kinase, putative 0.0041 0.0024 0.0087
Echinococcus multilocularis serine threonine protein kinase 0.0222 0.1328 0.1932
Onchocerca volvulus 0.0045 0.0055 0.0057
Onchocerca volvulus 0.0138 0.0721 0.1622
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0012 0.0012
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0381 0.2465 0.3586
Echinococcus multilocularis NCK adaptor protein 0.0063 0.0188 0.0273
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0518 0.3451 0.4165
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Plasmodium falciparum cGMP-dependent protein kinase 0.0057 0.014 0.0334
Echinococcus multilocularis peroxidasin 0.0042 0.0033 0.0048
Loa Loa (eye worm) hypothetical protein 0.0063 0.0185 0.0185
Echinococcus granulosus contactin 0.0045 0.0052 0.0063
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0052 0.0052
Schistosoma mansoni kinase 0.033 0.2099 0.4357
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0407 0.265 1
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.1131 0.2348
Entamoeba histolytica protein kinase, putative 0.016 0.0877 0.3236
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0051 0.0102 0.0148
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0128 0.0649 0.2378
Echinococcus multilocularis unc 13 (munc13) 0.0042 0.0035 0.0051
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0079 0.0299 0.0361
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.008 0.008
Schistosoma mansoni tyrosine kinase 0.01 0.0452 0.0938
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0039 0.0009 0.0013
Echinococcus granulosus casein kinase ii subunit alpha 0.0106 0.049 0.0591
Loa Loa (eye worm) hypothetical protein 0.0138 0.0721 0.0721
Schistosoma mansoni tyrosine kinase 0.0273 0.1688 0.3504
Trypanosoma brucei cdc2-related kinase 3 0.0128 0.0649 0.2296
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0053 0.011 0.011
Plasmodium falciparum calcium-dependent protein kinase 4 0.0053 0.011 0.0219
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0053 0.011 0.0326
Entamoeba histolytica protein kinase domain containing protein 0.0041 0.0024 0.0087
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0216 0.128 0.128
Echinococcus multilocularis tyrosine protein kinase shark 0.0072 0.0249 0.0363
Entamoeba histolytica serine/threonine protein kinase, putative 0.0053 0.011 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0714 0.2545
Onchocerca volvulus 0.0057 0.0138 0.0251
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0053 0.011 0.0159
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0086 0.035 0.035
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0382 0.2472 0.9322
Entamoeba histolytica protein kinase, putative 0.0329 0.2095 0.7729
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0045 0.0052 0.0107
Brugia malayi RhoGAP domain containing protein 0.0041 0.0024 0.0024
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0042 0.0031 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.128 0.2658
Loa Loa (eye worm) hypothetical protein 0.0165 0.0917 0.0917
Echinococcus multilocularis roundabout 2 0.0134 0.0697 0.1014
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0198 0.1153 0.1153
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.007 0.0236 0.0236
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Schistosoma mansoni cell adhesion molecule 0.0042 0.0031 0.0065
Echinococcus granulosus Glutaredoxin protein 5 0.0147 0.0788 0.0951
Schistosoma mansoni cell adhesion molecule 0.0045 0.0052 0.0107
Brugia malayi Ras association domain family 1 isoform A 0.0041 0.0024 0.0024
Schistosoma mansoni unc-13 (munc13) 0.0042 0.0035 0.0073
Plasmodium falciparum protein kinase, putative 0.0063 0.0181 0.0493
Schistosoma mansoni cell adhesion molecule 0.0045 0.0052 0.0107
Echinococcus multilocularis tyrosine protein kinase Fyn 0.017 0.0952 0.1385
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0195 0.1131 0.1645
Loa Loa (eye worm) RasGEF domain-containing protein 0.0041 0.0024 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0052 0.0075
Echinococcus multilocularis protein kinase c eta type 0.0041 0.0024 0.0035
Echinococcus granulosus tyrosine protein kinase Lyn 0.0196 0.1137 0.1372
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0407 0.265 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.0331 0.0331
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Schistosoma mansoni unc-13 (munc13) 0.0042 0.0035 0.0073
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0045 0.0055 0.0114
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0398
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0173 0.0972 0.3539
Echinococcus multilocularis Diacylglycerol kinase theta 0.0041 0.0024 0.0035
Schistosoma mansoni nephrin 0.0113 0.0541 0.1123
Echinococcus granulosus lachesin 0.0042 0.0031 0.0038
Entamoeba histolytica protein kinase , putative 0.016 0.0877 0.3236
Brugia malayi protein kinase C II. 0.0216 0.1282 0.1282
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Brugia malayi map kinase activated protein kinase protein 2 0.0455 0.2999 0.2999
Echinococcus granulosus roundabout 2 0.0045 0.0052 0.0063
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0053 0.011 0.011
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0059 0.0152 0.0382
Echinococcus multilocularis rac serine:threonine kinase 0.0181 0.1033 0.1503
Plasmodium falciparum glycogen synthase kinase 3 0.014 0.0734 0.2621
Echinococcus multilocularis neuroglian 0.0045 0.0052 0.0075
Loa Loa (eye worm) TK/ABL protein kinase 0.0319 0.2018 0.2018
Echinococcus multilocularis mitogen activated protein kinase 11 0.0176 0.0993 0.1445
Trypanosoma brucei protein kinase, putative 0.0086 0.035 0.1144
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0358 0.1268
Echinococcus multilocularis nervana 2 0.0147 0.0788 0.1146
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.008 0.0166
Echinococcus multilocularis cyclin dependent kinase 1 0.0128 0.0649 0.0945
Echinococcus multilocularis lachesin 0.0042 0.0031 0.0045
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0126 0.0635 0.0635
Trypanosoma brucei polo-like protein kinase 0.0308 0.1942 0.7274
Echinococcus granulosus unc 13 munc13 0.0042 0.0035 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0195 0.1133 0.1133
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.006 0.0088
Brugia malayi cell division control protein 2 homolog 0.0128 0.0649 0.0649
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0216 0.1282 0.1282
Echinococcus granulosus aurora kinase A 0.016 0.0877 0.1058
Entamoeba histolytica protein kinase, putative 0.0072 0.0246 0.0906
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0088 0.0364 0.053
Brugia malayi SH2 domain containing protein 0.0072 0.0248 0.0248
Schistosoma mansoni titin 0.0042 0.0031 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.1469 0.3049
Loa Loa (eye worm) hypothetical protein 0.0339 0.2163 0.2163
Loa Loa (eye worm) hypothetical protein 0.0059 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0042 0.0033 0.0033
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0167 0.0932 0.1125
Brugia malayi Protein kinase domain containing protein 0.0039 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0283 0.1766 0.3666
Echinococcus multilocularis Immunoglobulin 0.009 0.0378 0.0549
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0087 0.0358 0.1174
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.265 0.55
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0174 0.0979 0.1424
Echinococcus granulosus rho-associated protein kinase 1 0.0477 0.3158 0.3811
Entamoeba histolytica p21-activated kinase 0.0097 0.0431 0.1589
Echinococcus multilocularis mitogen activated protein kinase 14 0.0176 0.0993 0.1445
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0225 0.1349 0.1349
Schistosoma mansoni tyrosine kinase 0.0074 0.0264 0.0548
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0299 0.1042
Echinococcus multilocularis roundabout 2 0.0045 0.0052 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0052 0.0052
Echinococcus multilocularis calcium activated potassium channel 0.0098 0.0439 0.0638
Entamoeba histolytica cell division protein kinase 2, putative 0.0128 0.0649 0.2396
Loa Loa (eye worm) TK/EGFR protein kinase 0.0709 0.4818 0.4818
Loa Loa (eye worm) hypothetical protein 0.0132 0.0677 0.0677
Onchocerca volvulus 0.0452 0.2973 0.6918
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0165 0.0917 0.0917
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0195 0.1131 0.1645
Brugia malayi Protein kinase domain containing protein 0.0329 0.2095 0.2095
Schistosoma mansoni protein kinase 0.0039 0.0009 0.0019
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0407 0.265 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0321 0.2034 0.2034
Schistosoma mansoni ste20-related kinase 0.023 0.1386 0.2877
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3198
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0259 0.159 0.1919
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.005 0.0091 0.0147
Echinococcus multilocularis tyrosine protein kinase Abl 0.0195 0.1129 0.1642
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0051 0.0102 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0439 0.091
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3198
Brugia malayi serine/threonine-protein kinase 6 0.016 0.0877 0.0877
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0174 0.0979 0.1181
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3854
Echinococcus multilocularis aurora kinase A 0.016 0.0877 0.1276
Echinococcus multilocularis hypothetical protein 0.0073 0.0254 0.0369
Echinococcus multilocularis growth factor receptor bound protein 2 0.0063 0.0188 0.0273
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0079 0.0299 0.0299
Brugia malayi casein kinase 1, delta 0.0071 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0098 0.0439 0.0439
Brugia malayi hypothetical protein 0.0283 0.1761 0.1761
Loa Loa (eye worm) thyroid receptor interactor 0.0097 0.0426 0.0426
Echinococcus multilocularis PAK box P21 Rho binding 0.0063 0.0185 0.0268
Trypanosoma brucei rac serine-threonine kinase, putative 0.0329 0.2095 0.7864
Brugia malayi SH2 domain containing protein 0.0072 0.0248 0.0248
Echinococcus multilocularis Rac GTPase activating protein 1 0.0041 0.0024 0.0035
Leishmania major protein kinase, putative 0.016 0.0877 0.3245
Giardia lamblia Kinase, AGC AKT 0.0126 0.0635 0.2239
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0051 0.0102 0.0148
Echinococcus granulosus casein kinase I delta 0.0071 0.024 0.0289
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0308 0.1942 0.2344
Echinococcus multilocularis activin receptor type 0.0063 0.0181 0.0263
Loa Loa (eye worm) TK protein kinase 0.0142 0.0749 0.0749
Echinococcus multilocularis tyrosine protein kinase Fgr 0.017 0.0952 0.1385
Schistosoma mansoni tyrosine kinase 0.01 0.0452 0.0938
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0039 0.0009 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0649 0.2296
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0041 0.0024 0.0024
Plasmodium falciparum calcium-dependent protein kinase 3 0.0053 0.011 0.0219
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0041 0.5
Toxoplasma gondii AGC kinase 0.0321 0.2034 0.7655
Schistosoma mansoni tyrosine kinase 0.0461 0.3042 0.6313
Leishmania major protein kinase A catalytic subunit isoform 1 0.0407 0.265 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0086 0.035 0.1238
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus granulosus tyrosine protein kinase Blk 0.0142 0.0749 0.0904
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0089 0.037 0.0446
Echinococcus granulosus N chimaerin 0.0076 0.0276 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0932 0.1935
Brugia malayi Temporarily assigned gene name protein 59 0.0153 0.0833 0.0833
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.035 0.1144
Echinococcus granulosus tyrosine protein kinase Fyn 0.017 0.0952 0.1149
Trichomonas vaginalis STE family protein kinase 0.0089 0.037 0.1219
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0039 0.0009 0.0011
Trichomonas vaginalis CK1 family protein kinase 0.0071 0.024 0.0719
Entamoeba histolytica diacylglycerol kinase, putative 0.0041 0.0024 0.009
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0071 0.024 0.029
Echinococcus granulosus casein kinase I delta 0.0071 0.024 0.0289
Echinococcus granulosus activin receptor type 0.0063 0.0181 0.0219
Echinococcus granulosus Rac GTPase activating protein 1 0.0041 0.0024 0.0029
Giardia lamblia Aurora kinase 0.016 0.0877 0.3173
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0299 0.1042
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0057 0.0139 0.0168
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0216 0.128 0.2938
Brugia malayi Variant SH3 domain containing protein 0.0045 0.0056 0.0056
Schistosoma mansoni protein kinase 0.0247 0.1508 0.313
Echinococcus granulosus tyrosine protein kinase otk 0.0042 0.0031 0.0038
Leishmania major protein kinase, putative 0.0072 0.0248 0.0849
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0122 0.0609 0.0609
Schistosoma mansoni ephrin receptor 0.004 0.0017 0.0035
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0106 0.049 0.049
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.016 0.0877 0.3236
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0331 0.107
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.014 0.0734 0.2699
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.035 0.1144
Brugia malayi protein kinase C3,putative 0.0165 0.0916 0.0916
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0142 0.0749 0.0904
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0132 0.0679 0.249
Giardia lamblia Kinase, CMGC MAPK 0.0086 0.035 0.1144
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0045 0.0053 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Loa Loa (eye worm) AGC/NDR protein kinase 0.0174 0.0979 0.0979
Leishmania major casein kinase, putative 0.0071 0.024 0.0817
Trichomonas vaginalis STE family protein kinase 0.0063 0.0185 0.0506
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0173 0.0972 0.3573
Loa Loa (eye worm) hypothetical protein 0.0132 0.0677 0.0677
Echinococcus multilocularis serine:threonine protein kinase N2 0.0068 0.0222 0.0323
Schistosoma mansoni hypothetical protein 0.0058 0.0146 0.0303
Brugia malayi hypothetical protein 0.0195 0.1133 0.1133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0009 0.0009
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0358 0.1268
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.014 0.029
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0052 0.0063
Entamoeba histolytica serine/threonine protein kinase, putative 0.0308 0.1942 0.7164
Entamoeba histolytica protein kinase, putative 0.0071 0.024 0.0886
Brugia malayi hypothetical protein 0.0072 0.0248 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Plasmodium falciparum casein kinase 2, alpha subunit 0.0106 0.049 0.1682
Entamoeba histolytica protein kinase 2, putative 0.0173 0.0972 0.3586
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0679 0.1409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0163 0.0905 0.0905
Leishmania major protein kinase A catalytic subunit 0.0407 0.265 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.017 0.0952 0.1385
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Loa Loa (eye worm) MH2 domain-containing protein 0.0143 0.0757 0.0757
Trypanosoma cruzi cdc2-related kinase 3 0.0128 0.0649 0.2378
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis Glutaredoxin protein 5 0.0147 0.0788 0.1146
Giardia lamblia Kinase, STE STE20 0.0087 0.0358 0.1174
Loa Loa (eye worm) hypothetical protein 0.0073 0.0254 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0649 0.1348
Giardia lamblia Kinase, NEK 0.0148 0.0797 0.2866
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0276 0.0276
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.015 0.0311
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0455 0.2999 0.4363
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0331 0.107
Loa Loa (eye worm) raf kinase 0.0041 0.0024 0.0024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0181 0.0593
Onchocerca volvulus 0.0283 0.1766 0.4079
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0734 0.2621
Echinococcus granulosus Immunoglobulin 0.009 0.0378 0.0456
Onchocerca volvulus 0.0071 0.024 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0715 0.1484
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.035 0.1238
Trypanosoma cruzi casein kinase, putative 0.0071 0.024 0.0817
Loa Loa (eye worm) hypothetical protein 0.0407 0.265 0.265
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.035 0.1144
Loa Loa (eye worm) hypothetical protein 0.0141 0.0747 0.0747
Trichomonas vaginalis STE family protein kinase 0.0089 0.037 0.1219
Brugia malayi diacylglycerol kinase 0.0041 0.0024 0.0024
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0063 0.0181 0.0597
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.0133
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0076 0.0276 0.0333
Onchocerca volvulus Tyrosine kinase homolog 0.0634 0.4284 1
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis tyrosine protein kinase Src42A 0.017 0.0952 0.1385
Echinococcus granulosus serine/threonine protein kinase 0.0181 0.1033 0.1247
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.016 0.0877 0.1276
Echinococcus multilocularis rho associated protein kinase 0.0477 0.3158 0.4594
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0052 0.0052
Trichomonas vaginalis AGC family protein kinase 0.016 0.0877 0.3173
Echinococcus multilocularis serine:threonine protein kinase 0.0122 0.0609 0.0886
Echinococcus granulosus mitogen activated protein kinase 14 0.0176 0.0993 0.1199
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0071 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0225 0.1349 0.1349
Loa Loa (eye worm) AUR protein kinase 0.016 0.0877 0.0877
Entamoeba histolytica protein kinase domain containing protein 0.0063 0.0181 0.0668
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1282 0.266
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0398
Trypanosoma cruzi p21-activated kinase 3, putative 0.0052 0.0102 0.0292
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0053 0.011 0.0321
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0039 0.0009 0.0009
Giardia lamblia Kinase, CMGC CK2 0.0106 0.049 0.1682
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0147 0.0788 0.0951
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.011 0.0227
Loa Loa (eye worm) CAMK protein kinase 0.0048 0.008 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0301 0.1891 0.275
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Brugia malayi putative serine/threonine kinase SADA gamma 0.0053 0.011 0.011
Loa Loa (eye worm) TK/INSR protein kinase 0.0515 0.3431 0.3431
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0071 0.024 0.0817
Echinococcus granulosus mitogen activated protein kinase 0.0086 0.035 0.0423
Echinococcus granulosus nervana 2 0.0147 0.0788 0.0951
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0009 0.0009
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.016
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0273 0.1688 0.2037
Loa Loa (eye worm) hypothetical protein 0.0072 0.0248 0.0248
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0128 0.0649 0.2381
Onchocerca volvulus 0.0072 0.0248 0.0511
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.1349 0.2799
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0089 0.037 0.0538
Echinococcus granulosus NDR protein kinase 0.0174 0.0979 0.1181
Schistosoma mansoni serine/threonine kinase 0.0098 0.0439 0.091
Schistosoma mansoni protein kinase C mu 0.0163 0.0905 0.1879
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1192 0.8286 1
Echinococcus multilocularis tyrosine protein kinase otk 0.0042 0.0031 0.0045
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0079 0.0299 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0439 0.091
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0128 0.0649 0.0649
Schistosoma mansoni netrin receptor unc5 0.0039 0.0012 0.0025
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0083 0.0331 0.0481
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Onchocerca volvulus 0.0072 0.0248 0.0511
Brugia malayi Peroxidasin 0.0042 0.0033 0.0033
Schistosoma mansoni septate junction protein 0.0042 0.0031 0.0065
Loa Loa (eye worm) hypothetical protein 0.0039 0.001 0.001
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.014 0.0734 0.1523
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.035 0.1238
Echinococcus granulosus tyrosine protein kinase Fyn 0.017 0.0952 0.1149
Echinococcus multilocularis tyrosine kinase 0.0072 0.0248 0.0361
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0176 0.0993 0.3621
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Leishmania major protein kinase, putative 0.0063 0.0181 0.0593
Loa Loa (eye worm) hypothetical protein 0.0076 0.0279 0.0279
Echinococcus granulosus protein kinase c iota type 0.0313 0.1978 0.2388
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0057 0.0139 0.0203
Entamoeba histolytica PH domain containing protein kinase, putative 0.0415 0.2711 1
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0216 0.128 0.1863
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0439 0.091
Entamoeba histolytica PH domain containing protein kinase, putative 0.0181 0.1033 0.3811
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0089 0.037 0.0538
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0045 0.0052 0.0075
Brugia malayi Stress-activated protein kinase jnk-1 0.0301 0.1891 0.1891
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0053 0.011 0.0217
Echinococcus multilocularis tyrosine protein kinase HCK 0.0107 0.0497 0.0723
Plasmodium falciparum NIMA related kinase 1 0.0148 0.0797 0.2866
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0273 0.1688 0.2456
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0063 0.0188 0.039
Brugia malayi Furin-like cysteine rich region family protein 0.0709 0.4818 0.4818
Brugia malayi Protein kinase domain containing protein 0.0072 0.0248 0.0248
Loa Loa (eye worm) AUR protein kinase 0.016 0.0877 0.0877
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0289 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0714 0.2545
Echinococcus multilocularis expressed conserved protein 0.0057 0.014 0.0203
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Echinococcus granulosus raf serine:threonine protein kinase 0.0078 0.0289 0.0348
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Schistosoma mansoni serine/threonine kinase 0.0174 0.0979 0.2032
Echinococcus granulosus glycogen synthase kinase 3 beta 0.014 0.0734 0.0885
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0172 0.0969 0.3527
Schistosoma mansoni protein kinase 0.0071 0.024 0.0498
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0052 0.0052
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0053 0.011 0.011
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0407 0.265 1
Giardia lamblia Kinase, CMGC GSK 0.014 0.0734 0.2621
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.0609 0.2142
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0132 0.0679 0.2409
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0071 0.024 0.0349
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0174 0.0979 0.1424
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus granulosus serine:threonine protein kinase 12 B 0.016 0.0877 0.1058
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0148 0.0797 0.2944
Echinococcus multilocularis mitogen activated protein kinase 0.0086 0.035 0.0509
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Schistosoma mansoni protein kinase 0.0063 0.0181 0.0376
Entamoeba histolytica protein kinase, putative 0.0061 0.0169 0.0623
Loa Loa (eye worm) hypothetical protein 0.009 0.0378 0.0378
Echinococcus multilocularis casein kinase I delta 0.0071 0.024 0.0349
Brugia malayi Protein kinase domain containing protein 0.0216 0.128 0.128
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0148 0.0797 0.2904
Schistosoma mansoni tyrosine kinase 0.0231 0.1387 0.2878
Echinococcus multilocularis protein kinase c epsilon type 0.0216 0.1282 0.1864
Brugia malayi RhoGAP domain containing protein 0.0076 0.0276 0.0276
Giardia lamblia Kinase, AGC PKA 0.0407 0.265 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.014 0.0734 0.0734
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0274 0.1697 0.2048
Schistosoma mansoni tyrosine kinase 0.0078 0.0295 0.0613
Brugia malayi Protein kinase domain containing protein 0.0072 0.0248 0.0248
Trypanosoma cruzi aurora B kinase, putative 0.016 0.0877 0.3245
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Toxoplasma gondii histone kinase SNF1, putative 0.0053 0.011 0.0324
Echinococcus multilocularis mitogen activated protein kinase 14 0.0176 0.0993 0.1445
Schistosoma mansoni tyrosine kinase 0.0709 0.4818 1
Echinococcus multilocularis serine:threonine protein kinase 3 0.0292 0.1827 0.2658
Echinococcus granulosus cGMP dependent protein kinase 1 0.0057 0.014 0.0169
Echinococcus multilocularis tyrosine protein kinase Fyn 0.017 0.0952 0.1385
Entamoeba histolytica diacylglycerol kinase, putative 0.0041 0.0024 0.009
Echinococcus multilocularis netrin receptor unc 5 0.0039 0.0012 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus multilocularis myosin iiia 0.0087 0.0358 0.0521
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0047 0.0071 0.0103
Echinococcus multilocularis nervana 2 0.0147 0.0788 0.1146
Echinococcus granulosus serine threonine protein kinase nrc 0.0173 0.0972 0.1173
Trypanosoma cruzi casein kinase, putative 0.0071 0.024 0.0817
Entamoeba histolytica protein kinase, putative 0.0071 0.024 0.0886
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0053 0.011 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.006 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.1942 0.4031
Trypanosoma cruzi Protein kinase B 0.0181 0.1033 0.384
Giardia lamblia Kinase, CMGC CDK 0.0128 0.0649 0.2296
Brugia malayi serine/threonine-protein kinase plk-2 0.0308 0.1942 0.1942
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0045 0.0056 0.0056
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0167 0.0932 0.0932
Schistosoma mansoni cellular tumor antigen P53 0.0059 0.0157 0.0325
Echinococcus granulosus protein kinase C gamma type 0.0222 0.1328 0.1603
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.3158 0.6555
Loa Loa (eye worm) hypothetical protein 0.0165 0.0917 0.0917
Brugia malayi Pleckstrin Homology Domain 0.0049 0.0085 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.011 0.0227
Schistosoma mansoni single-minded 0.0058 0.015 0.0311
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis N chimaerin 0.0076 0.0276 0.0402
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.005 0.0091 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.016 0.0877 0.3236
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0128 0.0649 0.0784
Loa Loa (eye worm) AGC/PKN protein kinase 0.0242 0.1469 0.1469
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0407 0.265 0.3198
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0216 0.128 0.1545
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.011 0.0227
Loa Loa (eye worm) AUR protein kinase 0.016 0.0877 0.0877
Plasmodium falciparum serine/threonine protein kinase, putative 0.016 0.0877 0.3173
Brugia malayi Protein kinase domain containing protein 0.0072 0.0248 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Onchocerca volvulus 0.0072 0.0248 0.0511
Schistosoma mansoni protein kinase 0.0053 0.011 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.024 0.0498
Giardia lamblia Kinase, CK1 Casein kinase 0.0071 0.024 0.0719
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0086 0.035 0.1144
Brugia malayi Protein kinase domain 0.0089 0.037 0.037
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0726 0.4943 0.4943
Trypanosoma cruzi cdc2-related kinase 1 0.0128 0.0649 0.2378
Echinococcus multilocularis insulin receptor 0.0515 0.3431 0.499
Brugia malayi Protein kinase domain containing protein 0.0122 0.0609 0.0609
Echinococcus multilocularis tyrosine protein kinase Src64B 0.017 0.0952 0.1385
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Schistosoma mansoni tyrosine kinase 0.0424 0.2777 0.5765
Echinococcus granulosus protein kinase c epsilon type 0.0216 0.1282 0.1547
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Loa Loa (eye worm) hypothetical protein 0.0053 0.011 0.011
Trypanosoma cruzi casein kinase, putative 0.0071 0.024 0.0817
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0195 0.1131 0.1365
Echinococcus granulosus casein kinase I alpha 0.0071 0.024 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Echinococcus granulosus cyclin dependent kinase 0.0128 0.0649 0.0784
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Brugia malayi serine/threonine protein kinase 6 0.016 0.0877 0.0877
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.265 0.55
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Brugia malayi hypoxia-induced factor 1 0.018 0.1024 0.1024
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Brugia malayi Protein kinase domain containing protein 0.0208 0.1224 0.1224
Echinococcus granulosus casein kinase I alpha 0.0071 0.024 0.0289
Schistosoma mansoni protein kinase C 0.0042 0.0035 0.0073
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.014 0.0734 0.2701
Echinococcus multilocularis hemicentin 1 0.0042 0.0031 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0734 0.2621
Brugia malayi MH2 domain containing protein 0.0143 0.0757 0.0757
Echinococcus multilocularis hemicentin 1 0.0042 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0102 0.0465 0.0465
Brugia malayi Cam kinase protein 1 0.0053 0.011 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Brugia malayi Tyrosine-protein kinase abl-1 0.0195 0.1129 0.1129
Brugia malayi STE20-like kinase MST 0.0292 0.1827 0.1827
Echinococcus granulosus roundabout 2 0.0134 0.0697 0.0841
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0102 0.0212
Entamoeba histolytica casein kinase 1, putative 0.0071 0.024 0.0885
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.1891 0.3924
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.1131 0.2348
Echinococcus granulosus RNA directed DNA polymerase 0.0047 0.0071 0.0085
Entamoeba histolytica protein kinase, putative 0.0072 0.0246 0.0906
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.016
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0455 0.2999 0.362
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0137 0.0715 0.0863
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0024 0.0051
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0076 0.0276 0.0402
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0051 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0072 0.0248 0.0916
Onchocerca volvulus 0.0072 0.0248 0.0511
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0057 0.014 0.044
Schistosoma mansoni hypothetical protein 0.0041 0.0024 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0877 0.182
Entamoeba histolytica protein kinase, putative 0.0107 0.0497 0.1833
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.017 0.0952 0.1385
Giardia lamblia Kinase, STE STE20 0.0089 0.037 0.1219
Schistosoma mansoni protein kinase 0.0053 0.011 0.0228
Schistosoma mansoni protein kinase 0.016 0.0877 0.182
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0061 0.0169 0.0623
Brugia malayi ephrin receptor 1 precursor 0.0073 0.0254 0.0254
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0041 0.0024 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0726 0.4943 0.4943
Schistosoma mansoni tyrosine kinase 0.0072 0.0249 0.0518
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0141 0.0744 0.1083
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0063 0.0188 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0185 0.0508
Brugia malayi Immunoglobulin I-set domain containing protein 0.0093 0.0398 0.0398
Trichomonas vaginalis AGC family protein kinase 0.016 0.0877 0.3173
Onchocerca volvulus 0.014 0.0734 0.1652
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0048 0.008 0.008
Brugia malayi serine/threonine-protein kinase PAK 7 0.0263 0.1616 0.1616
Entamoeba histolytica hypothetical protein 0.0041 0.0024 0.009
Echinococcus granulosus mitogen activated protein kinase 3 0.0086 0.035 0.0423
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0031
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0024 0.0051
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0407 0.265 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0461 0.3042 0.6313
Echinococcus multilocularis tyrosine protein kinase Blk 0.0142 0.0749 0.1089
Schistosoma mansoni tyrosine kinase 0.017 0.0952 0.1977
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.162 0.3363
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0649 0.2296
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.014 0.0734 0.2699
Entamoeba histolytica protein kinase, putative 0.0063 0.0185 0.0681
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.049 0.1682
Echinococcus granulosus cyclin dependent kinase 5 0.0128 0.0649 0.0784
Brugia malayi Protein kinase domain containing protein 0.0128 0.0649 0.0649
Echinococcus granulosus nuclear factor of activated T cells 5 0.0088 0.0364 0.044
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0063 0.0188 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Trypanosoma brucei SNF1-related protein kinases, putative 0.0053 0.011 0.0217
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0053 0.5
Trypanosoma cruzi protein kinase A regulatory subunit 0.0045 0.0053 0.0106
Loa Loa (eye worm) transcription factor SMAD2 0.0143 0.0757 0.0757
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0167 0.0932 0.1356
Schistosoma mansoni septate junction protein 0.0042 0.0031 0.0065
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0216 0.128 0.128
Plasmodium vivax unspecified product 0.0106 0.049 0.1726
Loa Loa (eye worm) hypothetical protein 0.0063 0.0188 0.0188
Echinococcus granulosus tyrosine kinase 0.0072 0.0248 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0715 0.1484
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0051 0.0102 0.0148
Echinococcus multilocularis basement membrane specific heparan sulfate 0.009 0.0378 0.0549
Schistosoma mansoni Neurotrimin precursor (hNT) 0.009 0.0378 0.0784
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0649 0.1348
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Echinococcus multilocularis neuroglian 0.011 0.052 0.0757
Echinococcus granulosus fibroblast growth factor receptor 4 0.0273 0.1688 0.2037
Trichomonas vaginalis AGC family protein kinase 0.0207 0.1214 0.4472
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0123 0.0613 0.0613
Leishmania major protein kinase, putative 0.0053 0.011 0.0322
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Loa Loa (eye worm) TK/ROR protein kinase 0.0057 0.0139 0.0139
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.017 0.0952 0.1385
Brugia malayi Hr1 repeat family protein 0.0242 0.1469 0.1469
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Echinococcus granulosus serine:threonine protein kinase 3 0.0292 0.1827 0.2205
Echinococcus granulosus growth factor receptor bound protein 2 0.0063 0.0188 0.0227
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0086 0.035 0.1238
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0167 0.0932 0.0932
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0042 0.0035 0.0051
Echinococcus granulosus tyrosine protein kinase HCK 0.0107 0.0497 0.06
Onchocerca volvulus 0.0076 0.0279 0.0582
Echinococcus multilocularis raf serine:threonine protein kinase 0.0078 0.0289 0.042
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0331 0.0687
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0112 0.0534 0.0644
Loa Loa (eye worm) AGC/PKA protein kinase 0.0407 0.265 0.265
Toxoplasma gondii AGC kinase 0.0407 0.265 1
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.035 0.0727
Plasmodium vivax casein kinase 1, putative 0.0071 0.024 0.0768
Echinococcus granulosus c src tyrosine kinase 0.01 0.0452 0.0546
Entamoeba histolytica protein kinase, putative 0.0054 0.0121 0.0445
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0051 0.0102 0.0211
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.01 0.0452 0.0938
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0052 0.0102 0.0188
Brugia malayi hypothetical protein 0.0093 0.0398 0.0398
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1942 0.7274
Echinococcus granulosus protein kinase c eta type 0.0041 0.0024 0.0029
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0407 0.265 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Schistosoma mansoni ephrin receptor 0.0113 0.0543 0.1127
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0083 0.0331 0.0399
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0071 0.024 0.024
Echinococcus multilocularis serine:threonine protein kinase N2 0.0242 0.1469 0.2137
Echinococcus multilocularis roundabout 2 0.0045 0.0052 0.0075
Plasmodium falciparum calcium-dependent protein kinase 5 0.0053 0.011 0.0219
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0141 0.0744 0.0898
Echinococcus granulosus casein kinase I alpha 0.0071 0.024 0.0289
Toxoplasma gondii casein kinase I 0.0071 0.024 0.0821
Brugia malayi Prion-like- 0.0042 0.0031 0.0031
Leishmania major protein kinase A regulatory subunit, putative 0.0045 0.0053 0.0106
Leishmania major regulatory subunit of protein kinase a-like protein 0.0382 0.2472 0.9322
Echinococcus granulosus NCK adaptor protein 0.0063 0.0188 0.0227
Schistosoma mansoni protein kinase 0.0089 0.037 0.0767
Entamoeba histolytica PH domain containing protein kinase, putative 0.0415 0.2711 1
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0041 0.006
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0086 0.035 0.1238
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0163 0.0905 0.0905
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0308 0.1942 0.1942
Trypanosoma cruzi cdc2-related kinase 3 0.0128 0.0649 0.2378
Entamoeba histolytica protein kinase, putative 0.0174 0.0979 0.3611
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0142 0.0749 0.1089
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0381 0.2465 0.2975
Schistosoma mansoni serine/threonine-protein kinase 0.0181 0.1033 0.2144
Schistosoma mansoni nephrin 0.0045 0.0052 0.0107
Entamoeba histolytica protein kinase, putative 0.0321 0.2034 0.7504
Loa Loa (eye worm) TK/FER protein kinase 0.0072 0.0248 0.0248
Echinococcus multilocularis ephrin type A receptor 4 A 0.0113 0.0543 0.079
Trichomonas vaginalis AGC family protein kinase 0.005 0.0091 0.0147
Toxoplasma gondii AGC kinase 0.0407 0.265 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0086 0.035 0.1238
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0159 0.0871 0.1268
Schistosoma mansoni tyrosine kinase 0.0515 0.3431 0.7121
Echinococcus multilocularis RNA directed DNA polymerase 0.0047 0.0071 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0176 0.0993 0.0993
Schistosoma mansoni serine/threonine protein kinase 0.0274 0.1697 0.3522
Brugia malayi Sex muscle abnormal protein 5 0.0063 0.0188 0.0188
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0181 0.0493
Schistosoma mansoni protein kinase 0.0089 0.037 0.0767
Echinococcus multilocularis tumor protein p63 0.0404 0.2632 0.3828
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Entamoeba histolytica protein kinase domain containing protein 0.016 0.0877 0.3236
Echinococcus granulosus tyrosine protein kinase ABL1 0.0319 0.2018 0.2436
Echinococcus granulosus tyrosine protein kinase Src42A 0.0105 0.0485 0.0585
Echinococcus multilocularis epidermal growth factor receptor 0.0709 0.4818 0.7008
Trichomonas vaginalis AGC family protein kinase 0.0174 0.0979 0.3565
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0734 0.2706
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.009 0.0378 0.0784
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0079 0.0299 0.1102
Schistosoma mansoni protein kinase 0.0063 0.0185 0.0383
Brugia malayi Fes/CIP4 homology domain containing protein 0.0097 0.0426 0.0426
Schistosoma mansoni growth factor receptor-bound protein 0.0063 0.0188 0.039
Brugia malayi Fibronectin type III domain containing protein 0.0093 0.0398 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.265 0.55
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0273 0.1688 0.2456
Loa Loa (eye worm) hypothetical protein 0.0106 0.0494 0.0494
Echinococcus multilocularis protein kinase c iota type 0.0313 0.1978 0.2878
Entamoeba histolytica cell division protein kinase 2, putative 0.0128 0.0649 0.2396
Echinococcus granulosus tyrosine protein kinase Src42A 0.017 0.0952 0.1149
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0439 0.1484
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0146 0.0146
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0024
Schistosoma mansoni tyrosine kinase 0.0515 0.3431 0.7121
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Brugia malayi Immunoglobulin I-set domain containing protein 0.0292 0.1831 0.1831
Loa Loa (eye worm) CMGC/GSK protein kinase 0.014 0.0734 0.0734
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0152 0.0382
Onchocerca volvulus 0.0072 0.0248 0.0511
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0176 0.0993 0.3689
Brugia malayi RhoGEF domain containing protein 0.0041 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.011 0.0228
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0385 0.2493 0.2493
Echinococcus granulosus twitchin 0.0136 0.0705 0.0851
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0039 0.0009 0.0011
Entamoeba histolytica casein kinase, putative 0.0071 0.024 0.0885
Echinococcus granulosus serine:threonine protein kinase 0.0122 0.0609 0.0735
Echinococcus multilocularis casein kinase I delta 0.0071 0.024 0.0349
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.011 0.0217
Echinococcus granulosus cGMP dependent protein kinase 0.0057 0.014 0.0169
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0407 0.265 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0181 0.1033 0.384
Trichomonas vaginalis AGC family protein kinase 0.0329 0.2095 0.7864
Onchocerca volvulus 0.0578 0.3877 0.9043

Activities

Activity type Activity value Assay description Source Reference
Kd (functional) = 7.35 In vitro antagonistic activity against alpha-2 adrenergic receptor in isolated electrically stimulated rat vas deferens(clonidine-induced decrease in twitch height) ChEMBL. 3039138
Ki (binding) = 6.6 nM Ability to displace [3H]-clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro ChEMBL. 3039138

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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