Detailed information for compound 1123935

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 599.465 | Formula: C27H35BrO10
  • H donors: 2 H acceptors: 5 LogP: 2.31 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C1/C=C\C=C\C(=O)OCC[C@H]([C@@H](C(=O)OC[C@]23[C@]4([C@H](O1)C[C@H]([C@]14CO1)O[C@@H]3[C@H]([C@](CC2)(C)O)Br)C)O)C
  • InChi: 1S/C27H35BrO10/c1-15-8-11-34-18(29)6-4-5-7-19(30)37-16-12-17-27(14-36-27)25(16,3)26(13-35-23(32)20(15)31)10-9-24(2,33)21(28)22(26)38-17/h4-7,15-17,20-22,31,33H,8-14H2,1-3H3/b6-4+,7-5-/t15-,16-,17-,20+,21-,22-,24-,25-,26-,27+/m1/s1
  • InChiKey: BIUCBVHMYZOBBL-PLQSXFDKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0009
Onchocerca volvulus 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0185 0.0416 0.0416
Leishmania major UDP-galactopyranose mutase 0.0042 0.0069 0.0065
Schistosoma mansoni hypothetical protein 0.0043 0.007 0.0097
Plasmodium falciparum glutathione reductase 0.0097 0.0201 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0069 0.3388
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0869 0.2087 0.2915
Treponema pallidum NADH oxidase 0.0034 0.0047 0.0596
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0069 0.3292
Trypanosoma brucei histone deacetylase, putative 0.0018 0.0009 0.0005
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0009 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0046 0.0046
Echinococcus granulosus allatostatin A receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Treponema pallidum fructose-bisphosphate aldolase 0.0315 0.0733 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0003 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0078 0.0155 0.2076
Schistosoma mansoni opsin-like receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0046
Mycobacterium ulcerans dehydrogenase 0.0042 0.0069 0.0394
Loa Loa (eye worm) hypothetical protein 0.0063 0.0118 0.0118
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0112 0.0239 0.0333
Echinococcus granulosus histone deacetylase 6 0.0018 0.0009 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Echinococcus multilocularis GPCR, family 2 0.0019 0.0011 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0007 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0046 0.0046
Echinococcus granulosus inositol monophosphatase 1 0.0075 0.0149 0.0207
Schistosoma mansoni alpha-glucosidase 0.0141 0.0309 0.043
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0035 0.0031
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0016
Plasmodium vivax SET domain protein, putative 0.0063 0.0118 0.5866
Leishmania major cathepsin L-like protease 0.0065 0.0124 0.0121
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.011 0.0152
Onchocerca volvulus 0.0047 0.008 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0004 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0046 0.0063
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.004 0.0055
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0349 0.0487
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0069 0.3292
Trichomonas vaginalis ap endonuclease, putative 0.0078 0.0155 0.1287
Echinococcus granulosus glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Entamoeba histolytica histone deacetylase, putative 0.0062 0.0117 0.1551
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.004 0.004
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.013 0.095
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0007 0.0009
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Brugia malayi RE15519p 0.0033 0.0046 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0113 0.0157
Loa Loa (eye worm) histone deacetylase 3 0.0062 0.0117 0.0117
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0069 0.0069
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0602 0.1434 1
Onchocerca volvulus 0.0033 0.0046 0.0063
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Schistosoma mansoni neurotransmitter gated ion channel 0.0047 0.008 0.0111
Plasmodium vivax histone deacetylase, putative 0.0018 0.0009 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0069 0.3388
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.004 0.0055
Brugia malayi sulfakinin receptor protein 0.0033 0.0046 0.0046
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0065 0.0124 0.0173
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.004 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Loa Loa (eye worm) ctsf protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0135 0.0295 0.0291
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0009 0.0005
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0326 0.0326
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0047 0.0047
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0124 0.0121
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0185 0.0416 0.058
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0065 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0011 0.0011
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0022 0.0029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0078 0.0155 0.0151
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0046 0.0063
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0078 0.0155 0.769
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.011 0.0107
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0071 0.3537
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0071 0.0576
Schistosoma mansoni amine oxidase 0.0042 0.0069 0.0095
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.02 0.0279
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0018 0.012
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0117 0.0962
Brugia malayi MH2 domain containing protein 0.0128 0.0278 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0046 0.0063
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0013 0.0013
Plasmodium vivax histone deacetylase, putative 0.0018 0.0009 0.0388
Echinococcus granulosus glycine receptor subunit beta 0.0112 0.0239 0.0333
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0047 0.008 0.0111
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0135 0.0295 0.0291
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0046 0.0063
Trichomonas vaginalis glutaminase, putative 0.0293 0.0681 0.5753
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0078 0.0155 0.2076
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0046 0.0063
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0047 0.037
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0112 0.0239 0.0239
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.004 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.004 0.0055
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0047 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0007
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0201 0.0201
Schistosoma mansoni histone deacetylase 0.0062 0.0117 0.0162
Echinococcus multilocularis synaptojanin 1 0.0016 0.0004 0.0004
Schistosoma mansoni intermediate filament proteins 0.0026 0.003 0.0041
Brugia malayi excitatory GABA receptor EXP-1A 0.0112 0.0239 0.0239
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.02 0.0452 0.0452
Brugia malayi G-protein coupled receptor 0.0033 0.0046 0.0046
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0112 0.0239 0.0333
Brugia malayi Melatonin receptor type 1A 0.0033 0.0046 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Onchocerca volvulus 0.0016 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0047 0.008 0.0111
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0149 0.0145
Schistosoma mansoni ran 0.0021 0.0016 0.0022
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.0504 0.377
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0117 0.0113
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0078 0.0155 0.0151
Schistosoma mansoni ran 0.0021 0.0016 0.0022
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0046 0.0063
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0117 0.0962
Echinococcus multilocularis histone deacetylase 3 0.0062 0.0117 0.0162
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.004 0.0055
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0065
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0047 0.008 0.008
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus granulosus neuropeptide s receptor 0.0033 0.0046 0.0063
Onchocerca volvulus 0.0017 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0311
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0046 0.0063
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0047 0.22
Loa Loa (eye worm) hypothetical protein 0.0185 0.0416 0.0416
Brugia malayi Dopamine receptor protein 2 0.0033 0.0046 0.0046
Trypanosoma brucei histone deacetylase 1 0.0062 0.0117 0.0113
Brugia malayi hypothetical protein 0.0043 0.007 0.007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0011 0.0015
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0046 0.0063
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0009
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0075 0.0149 0.7386
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus FTZ F1 alpha 0.0031 0.004 0.0055
Brugia malayi RNA, U transporter 1 0.0081 0.0163 0.0163
Echinococcus granulosus histone deacetylase 7 0.0018 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0185 0.0416 0.058
Trypanosoma brucei glucosidase, putative 0.0036 0.0054 0.005
Trypanosoma brucei C-8 sterol isomerase, putative 0.4112 1 1
Onchocerca volvulus 0.0061 0.0113 0.0157
Schistosoma mansoni inositol monophosphatase 0.0075 0.0149 0.0207
Echinococcus granulosus glutamate NMDA receptor subunit 0.0072 0.0141 0.0195
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0054 0.0426
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Entamoeba histolytica hypothetical protein 0.0023 0.0022 0.0246
Trypanosoma brucei unspecified product 0.0019 0.0013 0.0009
Loa Loa (eye worm) glutathione reductase 0.0097 0.0201 0.0201
Trypanosoma brucei histone deacetylase 4 0.0018 0.0009 0.0005
Schistosoma mansoni hypothetical protein 0.0031 0.0042 0.0058
Chlamydia trachomatis glutamine binding protein 0.0039 0.0061 0.6419
Schistosoma mansoni vesicular acetylcholine transporter 0.2947 0.7157 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0075 0.0149 0.0958
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0007 0.0171
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.004 0.0055
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Brugia malayi histone deacetylase 3 (HD3) 0.0062 0.0117 0.0117
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0149 0.0145
Entamoeba histolytica hypothetical protein 0.0043 0.007 0.0912
Trypanosoma brucei trypanothione reductase 0.0097 0.0201 0.0198
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0039 0.0061 0.0432
Echinococcus multilocularis inositol monophosphatase 1 0.0075 0.0149 0.0207
Onchocerca volvulus 0.0049 0.0084 0.0116
Schistosoma mansoni survival motor neuron protein 0.0049 0.0084 0.0116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0044
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0015 0.0003 0.0003
Echinococcus granulosus orexin receptor type 2 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0138 0.0301 0.0301
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0015 0.0003 0.0003
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0078 0.0155 0.0151
Schistosoma mansoni amine GPCR 0.0033 0.0046 0.0063
Echinococcus granulosus tm gpcr rhodopsin 0.0552 0.1312 0.1833
Schistosoma mansoni cript-related 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Brugia malayi Importin beta-1 subunit 0.0028 0.0035 0.0035
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.0009 0.0009
Schistosoma mansoni nocturnin 0.0016 0.0004 0.0004
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0311
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0046 0.0063
Loa Loa (eye worm) glutamate receptor 2 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0054 0.2658
Entamoeba histolytica hypothetical protein 0.0043 0.007 0.0912
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.004 0.004
Schistosoma mansoni importin beta-1 0.0028 0.0035 0.0048
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0046 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Echinococcus granulosus intermediate filament protein 0.0026 0.003 0.0041
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0004 0.0004
Trypanosoma brucei histone deacetylase 2 0.0018 0.0009 0.0005
Loa Loa (eye worm) RecQ helicase 0.0021 0.0018 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.011 0.0152
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0112 0.0239 0.0239
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0013 0.0017
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0018 0.0018
Brugia malayi hypothetical protein 0.0047 0.008 0.008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.0504 0.8786
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0078 0.0155 0.0216
Schistosoma mansoni ap endonuclease 0.0078 0.0155 0.0216
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0013 0.0017
Schistosoma mansoni biogenic amine receptor 0.0033 0.0046 0.0063
Echinococcus granulosus cathepsin l1 0.0017 0.0007 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.02 0.0279
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0041 0.0065 0.0089
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.004 0.0055
Schistosoma mansoni histone deacetylase 1 2 3 0.0018 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0019 0.0011 0.0015
Trichomonas vaginalis inositol monophosphatase, putative 0.0075 0.0149 0.1234
Brugia malayi Cation transporter family protein 0.0185 0.0416 0.0416
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.02 0.0279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Onchocerca volvulus 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0009
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0004 0.0143
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.2947 0.7157 0.7157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0046 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0001 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0047 0.2311
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.007 0.0097
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0069 0.0095
Schistosoma mansoni ATP-binding cassette transporter 0.0015 0.0003 0.0003
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0201 0.028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Loa Loa (eye worm) serotonin transporter b 0.0061 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.003
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0069 0.3402
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Trypanosoma cruzi sterol C-24 reductase, putative 0.0046 0.0079 0.0075
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0046 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0046 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.004 0.004
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Onchocerca volvulus 0.0135 0.0295 0.0411
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0046 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.011 0.0681
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0149 0.1234
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0124 0.0173
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0013 0.0009
Echinococcus granulosus lamin dm0 0.0026 0.003 0.0041
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.004 0.0055
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.004 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0111 0.0111
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0316 0.0441
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.004 0.004
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.004 0.004
Echinococcus granulosus dna polymerase eta 0.0019 0.0013 0.0017
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0046 0.0063
Schistosoma mansoni amine GPCR 0.0033 0.0046 0.0063
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0112 0.0239 0.0333
Echinococcus granulosus geminin 0.0676 0.1616 0.2256
Brugia malayi Thioredoxin reductase 0.0097 0.0201 0.0201
Onchocerca volvulus 0.0498 0.118 0.1648
Plasmodium falciparum thioredoxin reductase 0.0097 0.0201 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Mycobacterium ulcerans oxidoreductase 0.0042 0.0069 0.0394
Trypanosoma cruzi sterol C-24 reductase, putative 0.0046 0.0079 0.0075
Echinococcus multilocularis histone deacetylase 8 0.0018 0.0009 0.0011
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0004 0.0004
Echinococcus multilocularis histone deacetylase 1 0.0062 0.0117 0.0162
Plasmodium falciparum histone deacetylase, putative 0.0018 0.0009 0.0248
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0112 0.0239 0.0239
Brugia malayi histone deacetylase 1 (HD1) 0.0062 0.0117 0.0117
Echinococcus multilocularis glutamate receptor 2 0.0015 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Schistosoma mansoni vesicular amine transporter 0.02 0.0452 0.0631
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0049 0.0084 0.0116
Echinococcus multilocularis serotonin receptor 0.0157 0.0349 0.0487
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0046 0.0063
Leishmania major histone deacetylase, putative 0.0062 0.0117 0.0113
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.008 0.008
Leishmania major sterol C-24 reductase, putative 0.0046 0.0079 0.0075
Schistosoma mansoni amine oxidase 0.0042 0.0069 0.0095
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0118 0.0165
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0047 0.0044
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Loa Loa (eye worm) glutamate receptor 1 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0079
Plasmodium falciparum histone deacetylase 1 0.0062 0.0117 0.5724
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0112 0.0239 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0047 0.008 0.008
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0069 0.0491
Onchocerca volvulus 0.0017 0.0007 0.0009
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Schistosoma mansoni acetylcholine receptor-related 0.0047 0.008 0.0111
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.004 0.004
Schistosoma mansoni neuropeptide receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.004 0.004
Leishmania major trypanothione reductase 0.0097 0.0201 0.0198
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0112 0.0239 0.0239
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0035 0.0031
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0706 0.0706
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0009 0.0011
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0046 0.0063
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0054 0.0426
Echinococcus granulosus snurportin 1 0.0303 0.0706 0.0985
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.011 0.543
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.011 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.004 0.004
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0124 0.0121
Echinococcus multilocularis lamin 0.0026 0.003 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.02 0.0279
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0149 0.1234
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.004 0.004
Trypanosoma brucei C-14 sterol reductase, putative 0.0089 0.0184 0.018
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0042 0.2068
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0046 0.0063
Brugia malayi Histone deacetylase 1 0.0062 0.0117 0.0117
Trichomonas vaginalis set domain proteins, putative 0.0498 0.118 1
Echinococcus multilocularis snurportin 1 0.0303 0.0706 0.0985
Echinococcus multilocularis musashi 0.0026 0.003 0.0041
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0046 0.0063
Brugia malayi Histone deacetylase family protein 0.0018 0.0009 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0046 0.0046
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0112 0.0239 0.0333
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0124 0.0124
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0042 0.0058
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0005 0.0005
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0112 0.0239 0.0333
Schistosoma mansoni hypothetical protein 0.0033 0.0046 0.0063
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0364 0.0364
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0118 0.0165
Brugia malayi hypothetical protein 0.0042 0.0069 0.0069
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0078 0.0155 0.0151
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0078 0.0155 0.1141
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0065 0.0124 0.0173
Entamoeba histolytica hypothetical protein 0.0065 0.0124 0.1655
Onchocerca volvulus 0.0017 0.0007 0.0009
Plasmodium falciparum glutathione reductase 0.0034 0.0047 0.22
Echinococcus granulosus histone deacetylase 0.0018 0.0009 0.0011
Echinococcus multilocularis neuropeptide receptor A26 0.0033 0.0046 0.0063
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0046 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0046 0.0063
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.004 0.0055
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0013 0.0069
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0047 0.008 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0019 0.0011 0.0015
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0069 0.0095
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0112 0.0239 0.0239
Echinococcus granulosus histone deacetylase 8 0.0018 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Echinococcus multilocularis dna polymerase eta 0.0019 0.0013 0.0017
Brugia malayi steroid hormone receptor 0.0031 0.004 0.004
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0009 0.0011
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0022 0.0153
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0003
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0602 0.1434 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0033 0.0046 0.0063
Brugia malayi PHD-finger family protein 0.0031 0.0042 0.0042
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.004 0.0055
Onchocerca volvulus 0.0017 0.0007 0.0009
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0054 0.0074
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0015 0.0003 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0047 0.037
Echinococcus multilocularis lamin dm0 0.0026 0.003 0.0041
Trypanosoma brucei histone deacetylase 3 0.0018 0.0009 0.0005
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Leishmania major C-14 sterol reductase, putative 0.0089 0.0184 0.018
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0039 0.0061 0.6419
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0118 0.0165
Schistosoma mansoni neuropeptide receptor 0.0033 0.0046 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0054 0.0426
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0201 0.028
Entamoeba histolytica hypothetical protein 0.0043 0.007 0.0912
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0001 0.0001
Onchocerca volvulus Histone deacetylase 10 homolog 0.0018 0.0009 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0042 0.2051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Onchocerca volvulus 0.0065 0.0124 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.004 0.004
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0112 0.0239 0.0239
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0013
Onchocerca volvulus 0.0033 0.0046 0.0063
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0046 0.0063
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0046 0.0063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0047 0.0242
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0016 0.0004 0.0004
Brugia malayi ORL1-like opioid receptor 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0149 0.0145
Loa Loa (eye worm) hypothetical protein 0.0157 0.0349 0.0349
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0112 0.0239 0.0239
Echinococcus granulosus neuropeptide receptor 0.0033 0.0046 0.0063
Brugia malayi Glutamate receptor 2 precursor 0.0015 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0054 0.0426
Onchocerca volvulus 0.0017 0.0007 0.0009
Plasmodium vivax glutathione reductase, putative 0.0097 0.0201 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0046 0.0063
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Echinococcus multilocularis neuropeptide s receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Schistosoma mansoni neuropeptide receptor 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0046 0.0046
Schistosoma mansoni amine GPCR 0.0033 0.0046 0.0063
Treponema pallidum sodium- and chloride- dependent transporter 0.0061 0.0113 0.1502
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0078 0.0155 0.2076
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0046 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.02 0.0279
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Schistosoma mansoni adenoreceptor 0.0033 0.0046 0.0063
Echinococcus granulosus nAChR subunit 0.0065 0.0124 0.0173
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0046 0.0063
Brugia malayi histone deacetylase 11 0.0018 0.0009 0.0009
Toxoplasma gondii histone deacetylase HDAC4 0.0018 0.0009 0.0408
Brugia malayi hypothetical protein 0.0238 0.0546 0.0546
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.004 0.0055
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.004 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0238 0.0546 0.0546
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0046 0.0063
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0124 0.0121
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0033 0.0046 0.0063
Toxoplasma gondii histone deacetylase HDAC2 0.0062 0.0117 0.5793
Plasmodium vivax importin-beta 2, putative 0.0028 0.0035 0.1692
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0047 0.2311
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0069 0.3292
Loa Loa (eye worm) histone deacetylase 0.0018 0.0009 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Schistosoma mansoni inositol monophosphatase 0.0075 0.0149 0.0207
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Onchocerca volvulus 0.0033 0.0046 0.0063
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0047 0.22
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0001 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0437 0.1033 0.1033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.004 0.0055
Trichomonas vaginalis ran, putative 0.0021 0.0016 0.0108
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Onchocerca volvulus 0.0017 0.0007 0.0009
Schistosoma mansoni synaptojanin 0.0016 0.0004 0.0004
Leishmania major C-8 sterol isomerase-like protein 0.4112 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.02 0.0279
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0112 0.0239 0.0239
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0058 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0046 0.0063
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0047 0.2327
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0046 0.0063
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0072 0.0099
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0039 0.0061 0.0786
Brugia malayi glutaminase DH11.1 0.0293 0.0681 0.0681
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) glutaminase 2 0.0293 0.0681 0.0681
Echinococcus multilocularis lamin b receptor 0.0089 0.0184 0.0255
Brugia malayi ecdysone receptor 0.0014 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0033 0.0046 0.0063
Toxoplasma gondii histone deacetylase HDAC5 0.0018 0.0009 0.0408
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0113 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0118 0.0165
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0054 0.0054
Schistosoma mansoni alpha-glucosidase 0.0141 0.0309 0.043
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0022 0.0029
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0009 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0046 0.0063
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0069 0.0095
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0071 0.0576
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0013 0.0017
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0047 0.0044
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Onchocerca volvulus 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0676 0.1616 0.2256
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0005 0.0006
Echinococcus multilocularis sex peptide receptor 0.0033 0.0046 0.0063
Onchocerca volvulus 0.0017 0.0007 0.0009
Brugia malayi jmjC domain containing protein 0.0103 0.0216 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0118 0.5875
Onchocerca volvulus 0.0033 0.0046 0.0063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0242
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0112 0.0239 0.0333
Mycobacterium tuberculosis Probable oxidoreductase 0.0245 0.0564 0.4223
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0046 0.0063
Schistosoma mansoni coup transcription factor 0.0031 0.004 0.0055
Onchocerca volvulus 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0047 0.2327
Brugia malayi Histone deacetylase family protein 0.0018 0.0009 0.0009
Brugia malayi nuclear receptor NHR-67 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0175
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0046 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.011 0.0681
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0046 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0054 0.005
Schistosoma mansoni neuropeptide receptor 0.0033 0.0046 0.0063
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0069 0.3388
Schistosoma mansoni nAChR subunit 0.0047 0.008 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0071 0.3537
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0185 0.0416 0.058
Brugia malayi exodeoxyribonuclease III family protein 0.0078 0.0155 0.0155
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0003 0.0003
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0042 0.0058
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0001 0.0001
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.004 0.0055
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0078 0.0155 1
Onchocerca volvulus 0.0042 0.0069 0.0095
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0003
Loa Loa (eye worm) cysteine protease 0.0017 0.0007 0.0007
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.004 0.0055
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.004 0.0055
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0047 0.008 0.0111
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.009 0.0087
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0004 0.0004
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0069 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0278 0.0278
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0112 0.0239 0.0239
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0009
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0009 0.0011
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0007 0.0171
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0004 0.0004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0054 0.0426
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.011 0.0681
Toxoplasma gondii cathepsin CPL 0.0017 0.0007 0.0332
Echinococcus multilocularis serotonin transporter 0.0061 0.0113 0.0157
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0016 0.0779
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0046 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0303 0.0706 0.0985
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus granulosus nmda type glutamate receptor 0.0054 0.0098 0.0136
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0069 1
Echinococcus granulosus histone deacetylase 6 0.0018 0.0009 0.0011
Schistosoma mansoni myosin xvIII 0.0033 0.0046 0.0063
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.004 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Echinococcus multilocularis serotonin receptor 0.0157 0.0349 0.0487
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0043 0.007 0.0912
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0018 0.012
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0046 0.0046
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0047 0.0044
Leishmania major DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0022 0.0029
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.004 0.0055
Brugia malayi Glutamate receptor 1 precursor 0.0015 0.0003 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0013 0.0077
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0058 0.008
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0046 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Echinococcus multilocularis nmda type glutamate receptor 0.0054 0.0098 0.0136
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0022 0.0153
Onchocerca volvulus 0.0033 0.0046 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Mycobacterium ulcerans glutaminase 0.0293 0.0681 0.47
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0264 0.0611 0.0611
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0118 0.0165
Brugia malayi nuclear receptor RXR 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0054 0.0426
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0035 0.1709
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0029
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0112 0.0239 0.0333
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.0504 0.377
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0009 0.0011
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0046 0.0046
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0029
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0069 0.0065
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0063 0.2982
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0005 0.0005
Schistosoma mansoni opsin-like receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0546 0.0762
Plasmodium falciparum histone deacetylase 2 0.0018 0.0009 0.0248
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.003 0.003
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0046 0.0063
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Echinococcus multilocularis geminin 0.0676 0.1616 0.2256
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0046 0.0063
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0112 0.0239 0.0333
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0154 0.034 0.2306
Echinococcus granulosus serotonin receptor 0.0033 0.0046 0.0063
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0046 0.0063
Trypanosoma cruzi C-14 sterol reductase, putative 0.0089 0.0184 0.018
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0033 0.0046 0.0063
Echinococcus multilocularis nAChR subunit 0.0112 0.0239 0.0333
Schistosoma mansoni biogenic amine receptor 0.0033 0.0046 0.0063
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0084 0.0084
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0047 0.0044
Entamoeba histolytica Ran family GTPase 0.0021 0.0016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0078 0.0155 0.0216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0005 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Loa Loa (eye worm) acetylcholine receptor protein 0.0047 0.008 0.008
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0018 0.0024
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0001 0.0001
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0046 0.0063
Schistosoma mansoni amine GPCR 0.0033 0.0046 0.0063
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.007 0.0097
Loa Loa (eye worm) hypothetical protein 0.4112 1 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0004 0.0143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.004 0.004
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0054 0.0426
Brugia malayi Cation transporter family protein 0.0112 0.0239 0.0239
Plasmodium vivax histone deacetylase 1, putative 0.0062 0.0117 0.5785
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0035 0.0048
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0005 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0025 0.0025
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0326 0.0455
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.0733 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.011 0.0152
Mycobacterium tuberculosis Probable reductase 0.0221 0.0504 0.377
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0011 0.0015
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0009 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0069 0.0394
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0062 0.0117 0.0117
Brugia malayi putative neuropeptide receptor 0.0033 0.0046 0.0046
Schistosoma mansoni biogenic amine receptor 0.0033 0.0046 0.0063
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0364 0.0508
Brugia malayi Pre-SET motif family protein 0.0063 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis synaptic vesicular amine transporter 0.02 0.0452 0.0631
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0011 0.0392
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0058 0.0058
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0054 0.0054
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0011 0.0015
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0039 0.0061 0.034
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0113 0.0157
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Onchocerca volvulus 0.0031 0.004 0.0055
Brugia malayi neuropeptide F receptor 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0003
Onchocerca volvulus 0.0026 0.003 0.0041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0154 0.034 0.2539
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0013 0.0009
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0047 0.0242
Loa Loa (eye worm) norepinephrine transporter 0.0061 0.0113 0.0113
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0047 0.0596
Brugia malayi AKH receptor 0.0033 0.0046 0.0046
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0042 0.2068
Schistosoma mansoni thyroid hormone receptor 0.0031 0.004 0.0055
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0046 0.0063
Toxoplasma gondii exonuclease III APE 0.0078 0.0155 0.7695
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0013 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0201 0.1491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0047 0.0044
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0016 0.0022
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0201 0.0198
Brugia malayi nuclear hormone receptor 0.0014 0.0001 0.0001
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0112 0.0239 0.0333
Brugia malayi Inositol-1 0.0075 0.0149 0.0149
Echinococcus multilocularis glycine receptor subunit beta 0.0112 0.0239 0.0333
Onchocerca volvulus 0.0033 0.0046 0.0063
Brugia malayi hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus g protein coupled receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0005 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0046 0.0063
Leishmania major DNA polymerase eta, putative 0.0019 0.0013 0.0009
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0054 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Brugia malayi conserved hypotetical protein 0.0014 0.0001 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0046 0.0063
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0003 0.0003
Echinococcus granulosus glutamate receptor 2 0.0023 0.0022 0.0029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Brugia malayi Dopamine receptor 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0004 0.0004
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0112 0.0239 0.0239
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.02 0.02
Echinococcus granulosus synaptojanin 1 0.0016 0.0004 0.0004
Onchocerca volvulus Putative nachr subunit 0.0112 0.0239 0.0333
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0054 0.0426
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0019 0.0011 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.004 0.004
Giardia lamblia Fructose-bisphosphate aldolase 0.0315 0.0733 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0047 0.008 0.008
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0009 0.0005
Echinococcus multilocularis vesicular acetylcholine transporter 0.2947 0.7157 1
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0112 0.0239 0.0239
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis NMDA receptor 0.0015 0.0003 0.0003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Brugia malayi nuclear receptor NHR-88 0.0014 0.0001 0.0001
Echinococcus granulosus somatostatin receptor 0.0033 0.0046 0.0063
Toxoplasma gondii histone deacetylase HDAC3 0.0062 0.0117 0.5793
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.004 0.0055
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0245 0.0564 1
Loa Loa (eye worm) hypothetical protein 0.2102 0.5094 0.5094
Giardia lamblia Histone deacetylase 0.0062 0.0117 0.1551
Echinococcus multilocularis 0.0042 0.0069 0.0095
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0003 0.0003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Brugia malayi G-protein coupled receptor 0.0033 0.0046 0.0046
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0071 0.3523
Loa Loa (eye worm) hypothetical protein 0.0061 0.0113 0.0113
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0069 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0011 0.0011
Onchocerca volvulus 0.0033 0.0046 0.0063
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0046 0.0063
Plasmodium falciparum importin beta, putative 0.0028 0.0035 0.1572
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0009 0.0011
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0004 0.0004
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0005 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0013
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0046 0.0063
Echinococcus granulosus lamin 0.0026 0.003 0.0041
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0201 1
Schistosoma mansoni thyroid hormone receptor 0.0031 0.004 0.0055
Brugia malayi Serotonin receptor 0.0955 0.2296 0.2296
Trypanosoma cruzi Emopamil binding protein, putative 0.0135 0.0295 0.0291
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0022 0.0029
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0546 0.0762
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0022 0.0029
Schistosoma mansoni histamine h1 receptor 0.0033 0.0046 0.0063
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0046 0.0063
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0001 0.0001
Echinococcus multilocularis histone deacetylase 7 0.0018 0.0009 0.0011
Loa Loa (eye worm) ACC-1 protein 0.0112 0.0239 0.0239
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0065
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Brugia malayi GnHR receptor homolog 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Echinococcus granulosus glycine receptor subunit beta 0.0112 0.0239 0.0333
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0046 0.0063
Schistosoma mansoni hypothetical protein 0.0033 0.0046 0.0063
Brugia malayi neuropeptide F receptor 0.0033 0.0046 0.0046
Schistosoma mansoni nAChR subunit 0.0112 0.0239 0.0333
Brugia malayi Dopamine receptor protein 1 0.0033 0.0046 0.0046
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0007 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.0733 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0245 0.0564 0.4223
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Schistosoma mansoni nuclear hormone receptor 0.0031 0.004 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.2947 0.7157 1
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0063 0.0808
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0004 0.0004
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0069 0.0095
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0046 0.0063
Toxoplasma gondii thioredoxin reductase 0.0097 0.0201 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Echinococcus granulosus histone deacetylase 1 0.0062 0.0117 0.0162
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0035
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0013
Brugia malayi ecdysteroid receptor 0.0031 0.004 0.004
Loa Loa (eye worm) histone deacetylase 11 0.0018 0.0009 0.0009
Schistosoma mansoni acetylcholine receptor subunit beta 0.0047 0.008 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0007 0.0007
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0042 0.0058
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0349 0.0487
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0054 0.0426
Onchocerca volvulus 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Brugia malayi G protein-coupled receptor 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0016 0.0004 0.0004
Schistosoma mansoni synaptojanin 0.0016 0.0004 0.0004
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0042 0.0069 0.3402
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0154 0.034 0.5487
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.004 0.004
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0046 0.0063
Echinococcus granulosus bloom syndrome protein 0.0021 0.0018 0.0024
Brugia malayi intermediate filament protein 0.0026 0.003 0.003
Echinococcus granulosus g protein coupled receptor 0.0033 0.0046 0.0063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0118 0.0165
Onchocerca volvulus Alhambra homolog 0.0031 0.0042 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0069 0.0491
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0004 0.0004
Leishmania major GTP-binding protein, putative 0.0021 0.0016 0.0013
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0022 0.0153
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0216 0.0301
Loa Loa (eye worm) DR-78 0.0014 0.0001 0.0001
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.011 0.0106
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Echinococcus multilocularis histone deacetylase 0.0018 0.0009 0.0011
Onchocerca volvulus 0.0033 0.0046 0.0063
Trypanosoma brucei Emopamil binding protein, putative 0.0135 0.0295 0.0291
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0117 0.0113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.0504 0.377
Echinococcus granulosus fmrfamide receptor 0.0033 0.0046 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0046 0.0063
Brugia malayi nuclear receptor NHR-88 0.0031 0.004 0.004
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0216 0.0301
Brugia malayi Serotonin receptor 0.0033 0.0046 0.0046
Entamoeba histolytica cysteine protease, putative 0.0017 0.0007 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.004 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0046 0.0063
Schistosoma mansoni DNA polymerase eta 0.0019 0.0013 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0112 0.0239 0.0333
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Schistosoma mansoni opsin-like receptor 0.0033 0.0046 0.0063
Brugia malayi vesicular acetylcholine transporter unc-17 0.2947 0.7157 0.7157
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0046 0.0046
Echinococcus granulosus glutamate receptor subunit protein glur 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0047 0.008 0.008
Onchocerca volvulus 0.0063 0.0118 0.0165
Loa Loa (eye worm) hypothetical protein 0.0065 0.0124 0.0124
Echinococcus granulosus serotonin transporter 0.0061 0.0113 0.0157
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0011 0.0011
Onchocerca volvulus 0.0094 0.0196 0.0273
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0016 0.0022
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0069 0.0095
Loa Loa (eye worm) intermediate filament protein 0.0026 0.003 0.003
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0046 0.0046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.004 0.0055
Leishmania major importin beta-1 subunit, putative 0.0023 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0185 0.0416 0.058
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0047 0.0328
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0046 0.0046
Loa Loa (eye worm) LGC-31 protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0065 0.0124 0.0173
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.003 0.003
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0112 0.0239 0.0333
Echinococcus granulosus histone deacetylase 6 0.0018 0.0009 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0047 0.0044
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.004 0.0055
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0004 0.0004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.004 0.0055
Echinococcus granulosus peregrin 0.0035 0.0051 0.007
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0245 0.0564 0.4223
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0033 0.0046 0.0063
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0019 0.0011 0.0015
Plasmodium falciparum phd finger protein, putative 0.0031 0.0042 0.1936
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0112 0.0239 0.0333
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0004 0.0004
Schistosoma mansoni neurotransmitter gated ion channel 0.0047 0.008 0.0111
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0111 0.0111
Onchocerca volvulus 0.0033 0.0046 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Schistosoma mansoni lamin 0.0026 0.003 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Brugia malayi Abnormal catecholamine distribution protein 1 0.02 0.0452 0.0452
Trichomonas vaginalis ap endonuclease, putative 0.0078 0.0155 0.1287
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0046 0.0063
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0047 0.008 0.0111
Trypanosoma cruzi C-8 sterol isomerase, putative 0.4112 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.02 0.0279
Onchocerca volvulus 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) GABA receptor subunit 0.0065 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0016 0.0004 0.0004
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0004 0.0004
Loa Loa (eye worm) glutaminase 0.0293 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0047 0.008 0.008
Brugia malayi Pre-SET motif family protein 0.0437 0.1033 0.1033
Echinococcus granulosus dna polymerase kappa 0.0019 0.0013 0.0017
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0046 0.0063
Schistosoma mansoni Lamin B receptor (ERG24) 0.0089 0.0184 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0029
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.013 0.1229
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0046 0.0063
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.004 0.0055
Schistosoma mansoni histone deacetylase 0.0062 0.0117 0.0162
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0117 0.0962
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0039 0.0061 0.0786
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.004 0.0055
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0015 0.0003 0.0003
Echinococcus granulosus neuropeptide receptor 0.0033 0.0046 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.004 0.0055
Loa Loa (eye worm) hypothetical protein 0.0061 0.0113 0.0113
Onchocerca volvulus 0.0033 0.0046 0.0063
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0364 0.0508
Brugia malayi hypothetical protein 0.0047 0.008 0.008
Echinococcus multilocularis peregrin 0.0035 0.0051 0.007
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.011 0.0798
Plasmodium falciparum thioredoxin reductase 0.0034 0.0047 0.22
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0015 0.0003 0.0003
Echinococcus granulosus importin subunit beta 1 0.0028 0.0035 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0003
Echinococcus granulosus synaptic vesicular amine transporter 0.02 0.0452 0.0631
Loa Loa (eye worm) acetyltransferase 0.0148 0.0326 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0029
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0072 0.0099
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0004 0.0004
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0065 0.0124 0.0124
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0046 0.0046
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0009 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0278 0.0278
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0112 0.0239 0.0333
Onchocerca volvulus 0.0185 0.0416 0.058
Echinococcus granulosus lamin b receptor 0.0089 0.0184 0.0255
Onchocerca volvulus 0.0047 0.008 0.0111
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.004 0.0055
Echinococcus multilocularis glycine receptor subunit beta 0.0112 0.0239 0.0333
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) inositol-1 0.0075 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Brugia malayi follicle stimulating hormone receptor 0.0264 0.0611 0.0611
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.004 0.004
Brugia malayi jmjC domain containing protein 0.0038 0.0058 0.0058
Echinococcus granulosus g protein coupled receptor 0.0033 0.0046 0.0063
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0023 0.0022 0.0029
Giardia lamblia DINP protein human, muc B family 0.0019 0.0013 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0046 0.0063
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0733 0.6199
Echinococcus granulosus GPCR family 2 0.0019 0.0011 0.0015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.02 0.02
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0054 0.0688
Plasmodium vivax histone deacetylase 2, putative 0.0018 0.0009 0.0388
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0112 0.0239 0.0333
Schistosoma mansoni alpha glucosidase 0.0036 0.0054 0.0074
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0676 0.1616 0.2256
Echinococcus granulosus sex peptide receptor 0.0033 0.0046 0.0063
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0118 0.0165
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0364 0.0364
Giardia lamblia PHD finger protein 15 0.0031 0.0042 0.0525
Onchocerca volvulus 0.0026 0.003 0.0041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0058 0.008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0046 0.0063
Echinococcus granulosus histone deacetylase 3 0.0062 0.0117 0.0162
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0016 0.0798
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0075 0.0149 0.9424
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Brugia malayi nuclear receptor RXR 0.0016 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.004 0.004
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0063 0.0808
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.004 0.004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.007 0.0097
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0007 0.0171
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Brugia malayi nuclear hormone receptor 0.0031 0.004 0.004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0046 0.0063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0046 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0046 0.0046
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0149 0.0145
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.004 0.0055
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0054 0.0074
Leishmania major cathepsin L-like protease 0.0065 0.0124 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0015 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0046 0.0063
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0001 0.0001
Echinococcus multilocularis somatostatin receptor 0.0033 0.0046 0.0063
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0078 0.0155 0.7657
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0069
Schistosoma mansoni glutaminase 0.0293 0.0681 0.095
Leishmania major histone deacetylase, putative 0.0018 0.0009 0.0005
Echinococcus granulosus vesicular acetylcholine transporter 0.2947 0.7157 1
Brugia malayi CCR4 0.0016 0.0004 0.0004
Trypanosoma cruzi Emopamil binding protein, putative 0.0135 0.0295 0.0291
Leishmania major histone deacetylase, putative 0.0018 0.0009 0.0005
Echinococcus granulosus hypothetical protein 0.0033 0.0046 0.0063
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0046 0.0063
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0069 0.3388
Loa Loa (eye worm) hypothetical protein 0.0061 0.0113 0.0113
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0326 0.0455
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0124 0.0121
Brugia malayi hypothetical protein 0.0047 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.004 0.004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0124 0.0124
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0046 0.0046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0552 0.1312 0.1833
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0065
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0165 0.0229
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0003
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0042 0.0042
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.0504 0.377
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0112 0.0239 0.0333
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0124 0.0124
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0157 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0004 0.0143
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0046 0.0063
Brugia malayi larval opioid receptor 0.0033 0.0046 0.0046
Loa Loa (eye worm) fibroinase 0.0017 0.0007 0.0007
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Schistosoma mansoni glutamate receptor NMDA 0.0072 0.0141 0.0195
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0075 0.0149 0.199
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0046 0.0063
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.004 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0046 0.0063
Brugia malayi tailless protein 0.0014 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0124 0.0121
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0046 0.0063
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0004 0.0163
Onchocerca volvulus 0.0047 0.008 0.0111
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0004 0.0143
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0047 0.008 0.0111
Brugia malayi Bromodomain containing protein 0.0035 0.0051 0.0051
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0069 0.0394
Schistosoma mansoni sodium/chloride dependent transporter 0.0061 0.0113 0.0157
Brugia malayi hypothetical protein 0.0033 0.0046 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.004 0.0055
Brugia malayi Cation transporter family protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0135 0.0295 0.0291
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0007 0.0007
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0364 0.0508
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0559 0.133 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) ACC-1 protein 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0009
Echinococcus granulosus neuropeptide receptor A26 0.0033 0.0046 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0047 0.0044
Echinococcus granulosus glycine receptor subunit alpha 1 0.0112 0.0239 0.0333
Leishmania major hypothetical protein, conserved 0.0135 0.0295 0.0291
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.0504 0.377
Schistosoma mansoni lamin 0.0026 0.003 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Brugia malayi glutathione reductase 0.0097 0.0201 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0013 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0046 0.0063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Loa Loa (eye worm) histone deacetylase 1 0.0062 0.0117 0.0117
Leishmania major histone deacetylase, putative 0.0062 0.0117 0.0113
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0078 0.0155 0.0155
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0022 0.0029
Loa Loa (eye worm) solute carrier family 6 member 4 0.0061 0.0113 0.0113
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0072 0.0141 0.0195
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0117 0.0962
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0007 0.0009
Echinococcus granulosus nAChR subunit 0.0112 0.0239 0.0333
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0124 0.0124
Brugia malayi hypothetical protein 0.0047 0.008 0.008
Schistosoma mansoni ap endonuclease 0.0078 0.0155 0.0216
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0112 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0054 0.0097 0.0097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0058 0.008
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0112 0.0239 0.0333
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0046 0.0063
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0112 0.0239 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.004 0.004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0071 0.0099
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0003 0.0003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0078 0.0155 0.1002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0047 0.0065
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0054 0.0098 0.0136
Onchocerca volvulus 0.0033 0.0046 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0239 0.0239
Echinococcus multilocularis nAChR subunit 0.0065 0.0124 0.0173
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0054 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0009
Brugia malayi SWIRM domain containing protein 0.0042 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0054 0.005
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0046
Trypanosoma cruzi C-14 sterol reductase, putative 0.0089 0.0184 0.018
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.0009 0.0408
Loa Loa (eye worm) hypothetical protein 0.006 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.0065 0.0124 0.0121

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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