Detailed information for compound 116612

Basic information

Technical information
  • TDR Targets ID: 116612
  • Name: 133627-22-2
  • MW: 270.287 | Formula: C14H14N4O2
  • H donors: 1 H acceptors: 3 LogP: 1.38 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccnc2c1[nH]c(=O)c1c(n2CC)nccc1
  • InChi: 1S/C14H14N4O2/c1-3-18-12-9(5-4-7-15-12)14(19)17-11-10(20-2)6-8-16-13(11)18/h4-8H,3H2,1-2H3,(H,17,19)
  • InChiKey: NEXOHOYQUTXPTJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • AIDS-003199
  • AIDS003199
  • N11-Ethyl-4-methoxy-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
  • N11-Ethyl-4-methoxy-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni hypothetical protein Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma congolense RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma brucei RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
Plasmodium yoelii integrase-related Get druggable targets OG5_139608 All targets in OG5_139608
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.0896 0.0823 0.0913
Brugia malayi Protein kinase domain containing protein 0.363 0.4123 0.4575
Trichomonas vaginalis AGC family protein kinase 0.0566 0.0424 0.3735
Loa Loa (eye worm) TK/EGFR protein kinase 0.0955 0.0893 0.0991
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.108 0.1044 0.1159
Onchocerca volvulus 0.0437 0.0269 0.0337
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0231 0.002 0.0022
Schistosoma mansoni serine/threonine kinase 0.0443 0.0276 0.0677
Giardia lamblia Kinase, NEK 0.0268 0.0064 0.0563
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.035 0.0163 0.0181
Entamoeba histolytica protein kinase domain containing protein 0.0272 0.0069 0.0641
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0805 0.0713 0.0792
Trypanosoma cruzi protein kinase, putative 0.0231 0.002 0.0022
Giardia lamblia Kinase, STE STE20 0.1155 0.1135 1
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0528 0.0379 0.0379
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0525 0.0375 0.0416
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi Serine/threonine-protein kinase Pim-3 0.212 0.23 0.2552
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0982 0.0926 0.1028
Giardia lamblia Kinase, AGC PKA 0.0288 0.0089 0.0784
Echinococcus granulosus STE20 serine:threonine protein kinase 0.063 0.0501 0.0556
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1018 0.097 0.1077
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis protein kinase c iota type 0.0747 0.0642 0.0642
Echinococcus granulosus cyclin dependent kinase 5 0.0427 0.0257 0.0285
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0525 0.0375 0.0416
Trypanosoma cruzi cdc2-related kinase 1 0.0427 0.0257 0.0285
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.108 0.1044 0.1159
Echinococcus multilocularis peroxidasin 0.0263 0.0059 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi Protein kinase domain containing protein 0.1596 0.1667 0.185
Brugia malayi Protein kinase c protein 2 0.0348 0.0161 0.0179
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0525 0.0375 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0525 0.0375 0.3301
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0698 0.0583 0.0647
Loa Loa (eye worm) hypothetical protein 0.0292 0.0094 0.0104
Brugia malayi casein kinase I 0.059 0.0453 0.0503
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Trypanosoma cruzi casein kinase, putative 0.059 0.0453 0.0503
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1353 0.1375 0.1525
Echinococcus multilocularis expressed conserved protein 0.0266 0.0062 0.0062
Entamoeba histolytica tyrosin kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0566 0.0424 0.0471
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0231 0.002 0.0188
Giardia lamblia Kinase, STE STE20 0.0361 0.0177 0.1558
Echinococcus granulosus activated cdc42 kinase 1 0.1596 0.1667 0.185
Brugia malayi cell division control protein 2 homolog 0.0427 0.0257 0.0285
Trypanosoma brucei Casein kinase II 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0748 0.0644 0.0715
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0934 0.0868 0.0868
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2023 0.2183 0.2423
Loa Loa (eye worm) hypothetical protein 0.071 0.0598 0.0664
Trypanosoma brucei cdc2-related kinase 1 0.0427 0.0257 0.0285
Trichomonas vaginalis STE family protein kinase 0.0361 0.0177 0.1558
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.0437 0.0269 0.0298
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Plasmodium falciparum protein kinase, putative 0.0394 0.0217 0.1888
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase , putative 0.0566 0.0424 0.3979
Echinococcus granulosus dual specificity mitogen activated protein 0.1155 0.1135 0.126
Trichomonas vaginalis CMGC family protein kinase 0.1096 0.1064 0.9372
Entamoeba histolytica tyrosin kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0318 0.0124 0.0138
Schistosoma mansoni cell adhesion molecule 0.0292 0.0094 0.0231
Entamoeba histolytica tyrosin kinase, putative 0.0231 0.002 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0969 0.091 0.101
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0231 0.002 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis STE family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Entamoeba histolytica protein kinase, putative 0.0566 0.0424 0.3979
Loa Loa (eye worm) CAMK/PIM protein kinase 0.212 0.23 0.2552
Plasmodium falciparum serine/threonine protein kinase, putative 0.0566 0.0424 0.387
Echinococcus multilocularis mitogen activated protein kinase 14 0.768 0.9011 0.9011
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.06 0.0466 0.1143
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0631 0.0503 0.1235
Brugia malayi hypothetical protein 0.2677 0.2973 0.3299
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Plasmodium falciparum cGMP-dependent protein kinase 0.0266 0.0062 0.0403
Echinococcus granulosus rho-associated protein kinase 1 0.0761 0.066 0.0732
Plasmodium falciparum protein serine/threonine kinase-1 0.0969 0.091 0.853
Trichomonas vaginalis protein tyrosine kinase, putative 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.1596 0.1667 0.185
Trypanosoma cruzi casein kinase II, putative 0.0231 0.002 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2232 0.2435 0.2435
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.212 0.23 0.2552
Entamoeba histolytica protein kinase, putative 0.108 0.1044 0.9818
Brugia malayi Immunoglobulin I-set domain containing protein 0.1525 0.1582 0.1755
Onchocerca volvulus 0.0316 0.0123 0.0139
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0337 0.0148 0.0164
Entamoeba histolytica serine/threonine protein kinase, putative 0.0337 0.0148 0.1382
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0246 0.0038 0.0038
Brugia malayi SRC-1 0.1018 0.097 0.1077
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0426 0.0256 0.0284
Echinococcus multilocularis tyrosine protein kinase csk 0.0231 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0136 0.0334
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis serine:threonine protein kinase 0.0327 0.0135 0.0135
Echinococcus granulosus tyrosine protein kinase HCK 0.0649 0.0524 0.0582
Echinococcus granulosus receptor type guanylyl cyclase 0.0231 0.002 0.0022
Loa Loa (eye worm) TK/EPH protein kinase 0.0314 0.012 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0148 0.0363
Echinococcus multilocularis serine:threonine protein kinase 38 0.0519 0.0368 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.1642 0.1722 0.4227
Echinococcus multilocularis transfer RNA-Thr 0.1596 0.1667 0.1667
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Toxoplasma gondii aurora kinase 0.0566 0.0424 0.3985
Entamoeba histolytica hypothetical protein 0.0234 0.0023 0.0209
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.057 0.0429 0.1054
Echinococcus multilocularis protein kinase c epsilon type 0.0664 0.0543 0.0543
Brugia malayi intracellular kinase 0.1096 0.1064 0.118
Echinococcus granulosus cyclin dependent kinase 7 0.0631 0.0503 0.0558
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Onchocerca volvulus Serine\/threonine kinase homolog 0.0307 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0631 0.0503 0.0558
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Brugia malayi SH2 domain containing protein 0.0437 0.0269 0.0298
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0292 0.0094 0.0104
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus activated cdc42 kinase 1 0.1596 0.1667 0.185
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2142 0.2327 0.2327
Schistosoma mansoni serine/threonine protein kinase 0.0987 0.0933 0.2289
Echinococcus granulosus retinal guanylyl cyclase 2 0.0231 0.002 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica PH domain containing protein kinase, putative 0.074 0.0634 0.5955
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0427 0.0257 0.0285
Echinococcus granulosus protein kinase C gamma type 0.0561 0.0418 0.0463
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0282 0.0082 0.0091
Brugia malayi ephrin receptor 1 precursor 0.0262 0.0057 0.0063
Entamoeba histolytica protein kinase, putative 0.0234 0.0023 0.0209
Onchocerca volvulus 0.0896 0.0823 0.1087
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0231 0.002 0.0022
Entamoeba histolytica casein kinase, putative 0.059 0.0453 0.4251
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Echinococcus granulosus neuroglian 0.0746 0.0641 0.0712
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Schistosoma mansoni tyrosine kinase 0.1018 0.097 0.2381
Brugia malayi Protein kinase domain containing protein 0.0325 0.0133 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.2985 0.3344 0.8207
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.035 0.0163 0.04
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0583
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0969 0.091 0.8558
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Echinococcus multilocularis dual specificity 0.027 0.0067 0.0067
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1367 0.1391 0.1544
Brugia malayi ribosomal protein S6 kinase alpha 3 0.094 0.0875 0.0971
Echinococcus granulosus slit 2 protein 0.0254 0.0048 0.0053
Loa Loa (eye worm) hypothetical protein 0.0263 0.0059 0.0065
Leishmania major protein kinase, putative 0.0216 0.0001 0.0001
Echinococcus granulosus dual specificity 0.027 0.0067 0.0075
Echinococcus multilocularis titin 0.0372 0.019 0.019
Schistosoma mansoni tyrosine kinase 0.0814 0.0724 0.1776
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0969 0.091 0.101
Toxoplasma gondii STE kinase 0.0231 0.002 0.0188
Entamoeba histolytica hypothetical protein 0.0234 0.0023 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.1533 0.1591 0.3906
Trypanosoma brucei Pseudokinase, putative 0.0231 0.002 0.0022
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1017 0.0969 0.1075
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0268 0.0064 0.0421
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2164 0.2353 0.2353
Loa Loa (eye worm) hypothetical protein 0.0466 0.0304 0.0337
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0231 0.002 0.0022
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0231 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0569 0.0428 0.0475
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0698 0.0583 0.0647
Schistosoma mansoni ephrin receptor 0.0263 0.0059 0.0144
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0231 0.002 0.0049
Echinococcus granulosus dual specificity 0.027 0.0067 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0296 0.0098 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0254 0.0048 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0067 0.0165
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Schistosoma mansoni tyrosine kinase 0.1018 0.097 0.2381
Schistosoma mansoni serine/threonine protein kinase 0.0761 0.066 0.1619
Entamoeba histolytica protein kinase, putative 0.0644 0.0519 0.487
Brugia malayi C1-like domain containing protein 0.1017 0.0969 0.1075
Echinococcus granulosus titin 0.0372 0.019 0.0211
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0895 0.0821 0.0911
Loa Loa (eye worm) AUR protein kinase 0.0566 0.0424 0.047
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Trichomonas vaginalis AGC family protein kinase 0.0566 0.0424 0.3735
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0698 0.0583 0.5394
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.027 0.0067 0.0075
Loa Loa (eye worm) hypothetical protein 0.1367 0.1391 0.1544
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0631 0.0503 0.0558
Loa Loa (eye worm) hypothetical protein 0.071 0.0598 0.0664
Schistosoma mansoni protein kinase 0.2335 0.256 0.6283
Trichomonas vaginalis STE family protein kinase 0.1155 0.1135 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1018 0.097 0.097
Echinococcus granulosus Vam6:Vps39 protein 0.0631 0.0503 0.0558
Loa Loa (eye worm) hypothetical protein 0.0631 0.0503 0.0558
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1876 0.2005 0.2225
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1353 0.1375 0.1375
Schistosoma mansoni serine/threonine protein kinase 0.0664 0.0543 0.1332
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1018 0.097 0.097
Echinococcus multilocularis natriuretic peptide receptor 1 0.0231 0.002 0.002
Echinococcus multilocularis roundabout 2 0.0292 0.0094 0.0094
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Brugia malayi Variant SH3 domain containing protein 0.0249 0.0042 0.0047
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Echinococcus multilocularis aurora kinase A 0.0566 0.0424 0.0424
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1018 0.097 0.097
Schistosoma mansoni septate junction protein 0.026 0.0055 0.0135
Giardia lamblia Kinase, STE STE20 0.0216 0.0001 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0145 0.0356
Brugia malayi serine/threonine-protein kinase 6 0.0566 0.0424 0.047
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1295 0.1304 0.1304
Schistosoma mansoni protein kinase 0.0339 0.015 0.0369
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis lachesin 0.026 0.0055 0.0055
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0361 0.0177 0.0196
Giardia lamblia Kinase, CMGC DYRK 0.027 0.0067 0.0594
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0246 0.0038 0.0337
Echinococcus multilocularis serine:threonine protein kinase N2 0.1059 0.1019 0.1019
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis tyrosine protein kinase pr2 0.0231 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0268 0.0064 0.0563
Trypanosoma cruzi protein kinase, putative 0.0231 0.002 0.0022
Schistosoma mansoni tyrosine kinase 0.0653 0.0529 0.1299
Echinococcus multilocularis cyclin dependent kinase 19 0.1642 0.1722 0.1722
Trichomonas vaginalis STE family protein kinase 0.0361 0.0177 0.1558
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0231 0.002 0.0022
Brugia malayi Protein kinase domain containing protein 0.635 0.7406 0.8219
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Brugia malayi Temporarily assigned gene name protein 59 0.0631 0.0503 0.0558
Echinococcus granulosus raf serine:threonine protein kinase 0.0375 0.0193 0.0215
Brugia malayi Receptor family ligand binding region containing protein 0.0231 0.002 0.0022
Echinococcus multilocularis protein kinase 0.0231 0.002 0.002
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0408 0.0233 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0136 0.0334
Echinococcus multilocularis tyrosine protein kinase HCK 0.0649 0.0524 0.0524
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0748 0.0644 0.0715
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0631 0.0503 0.0558
Echinococcus multilocularis cyclin dependent kinase 5 0.0427 0.0257 0.0257
Schistosoma mansoni titin 0.0372 0.019 0.0467
Echinococcus granulosus protein kinase c epsilon type 0.0664 0.0543 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0491 0.0333 0.0818
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Plasmodium falciparum serine/threonine protein kinase KIN 0.0337 0.0148 0.1227
Echinococcus granulosus roundabout 2 0.0292 0.0094 0.0104
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0525 0.0375 0.3523
Brugia malayi Sex muscle abnormal protein 5 0.0369 0.0187 0.0207
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0987 0.0933 0.1035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0292 0.0094 0.0104
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0631 0.0503 0.1234
Echinococcus multilocularis activated cdc42 kinase 1 0.1596 0.1667 0.1667
Echinococcus granulosus serine:threonine protein kinase 0.0327 0.0135 0.015
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus insulin receptor 0.1263 0.1265 0.1404
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0969 0.091 0.101
Entamoeba histolytica protein kinase domain containing protein 0.0349 0.0162 0.1511
Onchocerca volvulus 0.635 0.7406 1
Schistosoma mansoni tyrosine kinase 0.359 0.4074 1
Trypanosoma cruzi casein kinase, putative 0.059 0.0453 0.0503
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.0067 0.0075
Schistosoma mansoni serine/threonine-protein kinase 0.033 0.014 0.0343
Loa Loa (eye worm) hypothetical protein 0.0736 0.063 0.0699
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Entamoeba histolytica receptor protein kinase, putative 0.0231 0.002 0.0178
Trichomonas vaginalis STE family protein kinase 0.1155 0.1135 1
Echinococcus multilocularis roundabout 2 0.0861 0.0781 0.0781
Schistosoma mansoni serine/threonine RGC 0.0231 0.002 0.0049
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0736 0.063 0.0699
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.002 0.0049
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Echinococcus granulosus casein kinase I delta 0.059 0.0453 0.0503
Trichomonas vaginalis AGC family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Brugia malayi protein C17H12.11 0.0566 0.0424 0.0471
Brugia malayi Protein kinase domain containing protein 0.0345 0.0158 0.0175
Echinococcus multilocularis c src tyrosine kinase 0.06 0.0466 0.0466
Echinococcus granulosus roundabout 2 0.0861 0.0781 0.0866
Entamoeba histolytica protein kinase, putative 0.0525 0.0375 0.3516
Schistosoma mansoni serine/threonine protein kinase 0.2677 0.2973 0.7296
Loa Loa (eye worm) hypothetical protein 0.0829 0.0742 0.0823
Loa Loa (eye worm) RGC/RGC protein kinase 0.0231 0.002 0.0022
Echinococcus multilocularis casein kinase I delta 0.059 0.0453 0.0453
Trichomonas vaginalis CMGC family protein kinase 0.1096 0.1064 0.9372
Echinococcus multilocularis casein kinase I gamma 0.0345 0.0158 0.0158
Trichomonas vaginalis AGC family protein kinase 0.0552 0.0407 0.3585
Echinococcus multilocularis cyclin dependent kinase 9 0.0381 0.0201 0.0201
Brugia malayi Immunoglobulin I-set domain containing protein 0.3195 0.3598 0.3993
Echinococcus granulosus tyrosine protein kinase otk 0.026 0.0055 0.0061
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.059 0.0453 0.0503
Schistosoma mansoni rap gtpase-activating protein 0.0631 0.0503 0.1234
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.026 0.0055 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0934 0.0868 0.0963
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0231 0.002 0.002
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0296 0.0098 0.0109
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0337 0.0148 0.0148
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0292 0.0094 0.0094
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1096 0.1064 0.118
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Trichomonas vaginalis STE family protein kinase 0.0268 0.0064 0.0563
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0231 0.002 0.0022
Echinococcus granulosus casein kinase I gamma 0.0345 0.0158 0.0175
Echinococcus granulosus serine/threonine protein kinase 0.033 0.014 0.0155
Echinococcus multilocularis heat shock protein 70 0.0231 0.002 0.002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0431 0.0261 0.029
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0335 0.0145 0.0161
Echinococcus multilocularis tyrosine protein kinase csk 0.0231 0.002 0.002
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2164 0.2353 0.2612
Echinococcus granulosus NCK adaptor protein 0.0369 0.0187 0.0207
Echinococcus granulosus tyrosine kinase 0.0437 0.0269 0.0298
Echinococcus multilocularis tyrosine kinase 0.0231 0.002 0.002
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0231 0.002 0.002
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica protein kinase 2, putative 0.0288 0.0089 0.0826
Trichomonas vaginalis CK1 family protein kinase 0.059 0.0453 0.3989
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0583 0.0445 0.0494
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Brugia malayi bone morphogenetic protein type 1 receptor 0.0895 0.0821 0.0911
Echinococcus granulosus c-Jun N-terminal kinases 0.2985 0.3344 0.3711
Trypanosoma brucei SNF1-related protein kinases, putative 0.0337 0.0148 0.0164
Schistosoma mansoni tyrosine kinase 0.1936 0.2078 0.51
Giardia lamblia Kinase, CAMK CAMKL 0.037 0.0187 0.165
Schistosoma mansoni hypothetical protein 0.0318 0.0124 0.0305
Leishmania major casein kinase II, putative 0.0231 0.002 0.0022
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Loa Loa (eye worm) AGC/PKN protein kinase 0.1578 0.1646 0.1827
Brugia malayi hypothetical protein 0.0631 0.0503 0.0558
Onchocerca volvulus 0.0437 0.0269 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Schistosoma mansoni protein kinase 0.059 0.0453 0.1111
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis twitchin 0.034 0.0151 0.0151
Trichomonas vaginalis CMGC family protein kinase 0.0427 0.0257 0.2263
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0307 0.0112 0.0124
Giardia lamblia Kinase, NEK 0.0231 0.002 0.0176
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0704 0.0591 0.0591
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1096 0.1064 0.118
Brugia malayi Protein kinase domain containing protein 0.0437 0.0269 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Plasmodium vivax protein kinase Crk2 0.0427 0.0257 0.227
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0631 0.0503 0.1234
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.768 0.9011 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0969 0.091 0.101
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0698 0.0583 0.0647
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0934 0.0868 0.0963
Brugia malayi serine/threonine kinase 12 0.0566 0.0424 0.047
Schistosoma mansoni tyrosine kinase 0.2083 0.2256 0.5536
Echinococcus granulosus casein kinase ii subunit alpha 0.0231 0.002 0.0022
Echinococcus multilocularis raf serine:threonine protein kinase 0.0375 0.0193 0.0193
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Echinococcus multilocularis myosin iiia 0.0216 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Leishmania major casein kinase, putative 0.059 0.0453 0.0503
Loa Loa (eye worm) hypothetical protein 0.0525 0.0375 0.0416
Brugia malayi Stress-activated protein kinase jnk-1 0.2985 0.3344 0.3711
Plasmodium falciparum protein kinase 5 0.0427 0.0257 0.227
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0525 0.0375 0.3399
Schistosoma mansoni serine/threonine protein kinase 0.0631 0.0503 0.1235
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0698 0.0583 0.5137
Onchocerca volvulus 0.0761 0.066 0.0866
Echinococcus granulosus cyclin dependent kinase 19 0.1642 0.1722 0.1911
Brugia malayi Protein kinase domain containing protein 0.0437 0.0269 0.0298
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0855 0.0773 0.0858
Echinococcus granulosus roundabout 2 0.0292 0.0094 0.0104
Plasmodium falciparum calcium-dependent protein kinase 3 0.0525 0.0375 0.3399
Echinococcus granulosus casein kinase I delta 0.059 0.0453 0.0503
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.108 0.1044 0.1159
Echinococcus granulosus contactin 0.0292 0.0094 0.0104
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Giardia lamblia Kinase, AGC AKT 0.094 0.0875 0.7711
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0136 0.0334
Schistosoma mansoni cell adhesion molecule 0.026 0.0055 0.0135
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Echinococcus multilocularis dual specificity 0.108 0.1044 0.1044
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Giardia lamblia Kinase, CMGC CK2 0.0231 0.002 0.0176
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0246 0.0038 0.0042
Echinococcus multilocularis protein KINase family member (kin 25) 0.0757 0.0654 0.0654
Giardia lamblia Aurora kinase 0.0566 0.0424 0.3735
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Echinococcus multilocularis rho associated protein kinase 0.0761 0.066 0.066
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0569 0.0428 0.105
Entamoeba histolytica tyrosin kinase, putative 0.0272 0.0069 0.0641
Loa Loa (eye worm) TK/Met protein kinase 0.0231 0.002 0.0022
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1296 0.1305 0.1448
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica protein kinase, putative 0.1096 0.1064 1
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0525 0.0375 0.3523
Entamoeba histolytica hypothetical protein, conserved 0.0231 0.002 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0566 0.0424 0.3735
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0369 0.0187 0.0207
Brugia malayi Serine/threonine-protein kinase SULU 0.2677 0.2973 0.3299
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Entamoeba histolytica casein kinase, putative 0.0231 0.002 0.0177
Brugia malayi Protein kinase domain containing protein 0.0583 0.0445 0.0494
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0934 0.0868 0.0963
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Loa Loa (eye worm) hypothetical protein 0.0318 0.0124 0.0138
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0394 0.0217 0.0241
Brugia malayi Protein kinase domain containing protein 0.0427 0.0257 0.0285
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.0513 0.036 0.0399
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0698 0.0583 0.0647
Echinococcus granulosus tyrosine protein kinase csk 0.0231 0.002 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0969 0.091 0.2234
Echinococcus granulosus ephrin type A receptor 4 A 0.0296 0.0098 0.0109
Echinococcus granulosus neuroglian 0.0292 0.0094 0.0104
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0231 0.002 0.002
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.768 0.9011 1
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1155 0.1135 0.126
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.037 0.0187 0.1602
Echinococcus granulosus tyrosine kinase 0.0855 0.0773 0.0858
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Giardia lamblia Kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0899 0.0826 0.0917
Echinococcus granulosus tyrosine protein kinase Src42A 0.0639 0.0512 0.0569
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0566 0.0424 0.047
Entamoeba histolytica cell division protein kinase 2, putative 0.046 0.0296 0.2776
Schistosoma mansoni protein kinase 0.0394 0.0217 0.0533
Echinococcus granulosus tyrosine protein kinase csk 0.0231 0.002 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.0257 0.063
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1096 0.1064 0.118
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0231 0.002 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0292 0.0094 0.0094
Echinococcus granulosus dual specificity protein kinase clk2 0.0969 0.091 0.101
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0288 0.0089 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0148 0.0363
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3195 0.3598 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Loa Loa (eye worm) TK/CSK protein kinase 0.0231 0.002 0.0022
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0698 0.0583 0.5394
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi Protein kinase domain containing protein 0.2023 0.2183 0.2423
Toxoplasma gondii hypothetical protein 0.0748 0.0644 0.6056
Echinococcus granulosus tyrosine protein kinase Srms 0.0849 0.0766 0.085
Brugia malayi Cam kinase protein 1 0.0525 0.0375 0.0416
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0647
Brugia malayi Variant SH3 domain containing protein 0.035 0.0163 0.0181
Echinococcus multilocularis TGF beta receptor type 1 0.0827 0.0739 0.0739
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Toxoplasma gondii AGC kinase 0.0644 0.0519 0.4875
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0337 0.0148 0.0164
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0525 0.0375 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0098 0.024
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1876 0.2005 0.2005
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0407 0.0232 0.0232
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2335 0.256 0.2841
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1486 0.1534 0.1703
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.212 0.23 0.3087
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0231 0.002 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis hemicentin 1 0.026 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0384 0.0205 0.1917
Echinococcus granulosus serine:threonine protein kinase 0.0327 0.0135 0.015
Echinococcus multilocularis tyrosine protein kinase Srms 0.0855 0.0773 0.0773
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0067 0.0594
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0231 0.002 0.0022
Giardia lamblia Kinase, CMGC CLK 0.0969 0.091 0.802
Schistosoma mansoni protein kinase 0.153 0.1588 0.3898
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1096 0.1064 0.1064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1353 0.1375 0.1525
Echinococcus granulosus cGMP dependent protein kinase 1 0.0266 0.0062 0.0069
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0335 0.0145 0.0161
Schistosoma mansoni tyrosine kinase 0.0583 0.0445 0.1092
Echinococcus multilocularis c Jun NH2 terminal kinase 0.2985 0.3344 0.3344
Loa Loa (eye worm) IKK protein kinase 0.635 0.7406 0.8219
Loa Loa (eye worm) hypothetical protein 0.0631 0.0503 0.0558
Brugia malayi Protein kinase domain containing protein 0.0969 0.091 0.101
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1155 0.1135 0.126
Brugia malayi Tyrosine-protein kinase abl-1 0.1252 0.1253 0.139
Entamoeba histolytica protein kinase domain containing protein 0.0394 0.0217 0.2032
Loa Loa (eye worm) hypothetical protein 0.0854 0.0772 0.0857
Giardia lamblia Kinase, NEK 0.0268 0.0064 0.0563
Schistosoma mansoni vav2 0.0392 0.0214 0.0525
Brugia malayi EGF-like domain containing protein 0.0254 0.0048 0.0053
Trypanosoma cruzi casein kinase, putative 0.059 0.0453 0.0503
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0566 0.0424 0.3979
Echinococcus granulosus aurora kinase A 0.0566 0.0424 0.047
Echinococcus multilocularis NCK adaptor protein 0.0384 0.0205 0.0205
Schistosoma mansoni neuroglian 0.0292 0.0094 0.0231
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Brugia malayi hypothetical protein 0.0437 0.0269 0.0298
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0534 0.0386 0.0428
Trypanosoma brucei polo-like protein kinase 0.0307 0.0112 0.0124
Echinococcus multilocularis tyrosine protein kinase csk 0.0231 0.002 0.002
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Toxoplasma gondii histone kinase SNF1, putative 0.0337 0.0148 0.1391
Giardia lamblia Kinase, CMGC GSK 0.1096 0.1064 0.9372
Echinococcus granulosus natriuretic peptide receptor 1 0.0231 0.002 0.0022
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0307 0.0112 0.0112
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0372 0.019 0.0211
Entamoeba histolytica protein kinase, putative 0.0339 0.015 0.1405
Schistosoma mansoni protein kinase 0.0325 0.0133 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.0112 0.0275
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.027 0.0067 0.0075
Echinococcus multilocularis neuroglian 0.0292 0.0094 0.0094
Echinococcus granulosus cyclin dependent kinase 1 0.0427 0.0257 0.0285
Onchocerca volvulus 0.0854 0.0772 0.1018
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0744 0.0639 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Echinococcus granulosus tyrosine protein kinase Blk 0.0855 0.0773 0.0858
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase, putative 0.0686 0.0569 0.5348
Echinococcus granulosus casein kinase I alpha 0.059 0.0453 0.0503
Plasmodium falciparum NIMA related kinase 1 0.0268 0.0064 0.0421
Loa Loa (eye worm) hypothetical protein 0.0248 0.0041 0.0045
Echinococcus multilocularis cyclin dependent kinase 1 0.0427 0.0257 0.0257
Onchocerca volvulus 0.1096 0.1064 0.1413
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0528 0.0379 0.042
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0266 0.0062 0.0583
Echinococcus multilocularis serine:threonine protein kinase 0.0327 0.0135 0.0135
Entamoeba histolytica protein kinase domain containing protein 0.1096 0.1064 1
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.0601 0.0467 0.0518
Entamoeba histolytica protein kinase domain containing protein 0.027 0.0067 0.0624
Loa Loa (eye worm) hypothetical protein 0.0854 0.0772 0.0856
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1018 0.097 0.097
Schistosoma mansoni vam6/vps39 related 0.0631 0.0503 0.1234
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Echinococcus granulosus Immunoglobulin 0.0569 0.0428 0.0475
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.059 0.0453 0.0503
Entamoeba histolytica protein kinase domain containing protein 0.0335 0.0145 0.1355
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni kinase 0.0373 0.0192 0.047
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Entamoeba histolytica casein kinase 1, putative 0.059 0.0453 0.4251
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1155 0.1135 0.126
Trichomonas vaginalis STE family protein kinase 0.1155 0.1135 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0231 0.002 0.0176
Entamoeba histolytica protein kinase, putative 0.0369 0.0187 0.1747
Echinococcus multilocularis kinase suppressor of Ras 1 0.0231 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0519 0.0368 0.0408
Schistosoma mansoni protein kinase 0.2335 0.256 0.6283
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1348 0.1368 0.1368
Echinococcus granulosus serine:threonine protein kinase N2 0.1578 0.1646 0.1827
Trypanosoma cruzi casein kinase, putative 0.059 0.0453 0.0503
Echinococcus multilocularis tyrosine protein kinase Abl 0.1252 0.1253 0.1253
Echinococcus multilocularis 0.0899 0.0826 0.0826
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Trichomonas vaginalis STE family protein kinase 0.0339 0.015 0.1325
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0698 0.0583 0.0647
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0288 0.0089 0.0089
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0631 0.0503 0.0558
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0327 0.0135 0.015
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0698 0.0583 0.0647
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0583
Brugia malayi casein kinase 1, delta 0.059 0.0453 0.0503
Onchocerca volvulus 0.0437 0.0269 0.0337
Echinococcus granulosus lachesin 0.026 0.0055 0.0061
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0427 0.0257 0.0285
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Entamoeba histolytica serine/threonine protein kinase, putative 0.0307 0.0112 0.1044
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0216 0.0001 0.0001
Brugia malayi Furin-like cysteine rich region family protein 0.0955 0.0893 0.0991
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1018 0.097 0.097
Entamoeba histolytica hypothetical protein 0.0233 0.0022 0.02
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1096 0.1064 0.118
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0333 0.0143 0.0158
Onchocerca volvulus 0.0631 0.0503 0.0654
Brugia malayi Variant SH3 domain containing protein 0.0369 0.0187 0.0207
Onchocerca volvulus 0.035 0.0163 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0148 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.768 0.9011 1
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0335 0.0145 0.0145
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1353 0.1375 0.1525
Entamoeba histolytica protein kinase, putative 0.0649 0.0524 0.4924
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Schistosoma mansoni titin 0.026 0.0055 0.0135
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Entamoeba histolytica ankyrin repeat protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0748 0.0644 0.0715
Echinococcus granulosus tyrosine protein kinase Src64B 0.1018 0.097 0.1077
Brugia malayi cyclin-dependent kinase 9 0.0349 0.0162 0.0179
Schistosoma mansoni kinase 0.0349 0.0162 0.0397
Schistosoma mansoni tyrosine kinase 0.0583 0.0445 0.1092
Onchocerca volvulus 0.071 0.0598 0.0783
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0231 0.002 0.0022
Brugia malayi probable protein kinase 0.153 0.1588 0.1762
Onchocerca volvulus 0.2312 0.2531 0.34
Brugia malayi map kinase activated protein kinase protein 2 0.0528 0.0379 0.042
Echinococcus multilocularis Immunoglobulin 0.0569 0.0428 0.0428
Schistosoma mansoni tyrosine kinase 0.1263 0.1265 0.3106
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0427 0.0257 0.0285
Giardia lamblia Kinase, CMGC GSK 0.1096 0.1064 0.9372
Trypanosoma cruzi aurora B kinase, putative 0.0566 0.0424 0.047
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni vesicular amine transporter 0.0569 0.0428 0.105
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0408 0.0233 0.0259
Brugia malayi Egg laying defective protein 4 0.0266 0.0062 0.0069
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.108 0.1044 0.1159
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0491 0.0333 0.037
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0372 0.019 0.0211
Loa Loa (eye worm) hypothetical protein 0.0513 0.036 0.0399
Schistosoma mansoni tyrosine kinase 0.0583 0.0445 0.1092
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0569 0.0428 0.0428
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0394 0.0217 0.0241
Loa Loa (eye worm) hypothetical protein 0.0318 0.0124 0.0138
Loa Loa (eye worm) TK/FER protein kinase 0.0744 0.0639 0.0709
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0519 0.0368 0.0408
Echinococcus multilocularis serine:threonine protein kinase N2 0.0519 0.0368 0.0368
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0699 0.0584 0.0648
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0525 0.0375 0.0416
Trypanosoma brucei rac serine-threonine kinase, putative 0.0686 0.0569 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.1486 0.1534 0.3765
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0361 0.0177 0.0177
Echinococcus multilocularis tyrosine protein kinase 0.0231 0.002 0.002
Echinococcus granulosus tyrosine protein kinase pr2 0.0231 0.002 0.0022
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0698 0.0583 0.0647
Brugia malayi Immunoglobulin I-set domain containing protein 0.0601 0.0467 0.0518
Onchocerca volvulus 0.059 0.0453 0.0586
Brugia malayi Protein kinase domain containing protein 0.0316 0.0123 0.0136
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.035 0.0163 0.0163
Trypanosoma cruzi casein kinase, delta isoform, putative 0.059 0.0453 0.0503
Leishmania major protein kinase, putative 0.0525 0.0375 0.0416
Loa Loa (eye worm) TK/ALK protein kinase 0.4596 0.5288 0.5868
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus peroxidasin 0.0263 0.0059 0.0065
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1018 0.097 0.097
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0427 0.0257 0.0285
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0519 0.0368 0.0368
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0525 0.0375 0.0416
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0491 0.0333 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.0379 0.093
Echinococcus multilocularis casein kinase i 0.059 0.0453 0.0453
Loa Loa (eye worm) RhoGAP domain-containing protein 0.035 0.0163 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis roundabout 2 0.0292 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.0327 0.0135 0.015
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0407 0.0232 0.0258
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0307 0.0112 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0698 0.0583 0.1431
Echinococcus multilocularis epidermal growth factor receptor 0.0955 0.0893 0.0893
Entamoeba histolytica hypothetical protein 0.108 0.1044 0.9818
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Brugia malayi Protein kinase domain containing protein 0.0437 0.0269 0.0298
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0369 0.0187 0.1747
Trichomonas vaginalis AGC family protein kinase 0.0566 0.0424 0.3735
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0566 0.0424 0.0424
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0369 0.0187 0.0458
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.212 0.23 0.5645
Echinococcus multilocularis casein kinase ii subunit alpha 0.0231 0.002 0.002
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1096 0.1064 0.118
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0325 0.0133 0.0148
Brugia malayi SH2 domain containing protein 0.0744 0.0639 0.0709
Loa Loa (eye worm) RGC/RGC protein kinase 0.0231 0.002 0.0022
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0231 0.002 0.0176
Loa Loa (eye worm) gastrulation defective protein 1 0.1478 0.1525 0.1693
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0231 0.002 0.0049
Brugia malayi serine/threonine protein kinase 6 0.0566 0.0424 0.047
Echinococcus multilocularis mitogen activated protein kinase 14 0.768 0.9011 0.9011
Echinococcus granulosus twitchin 0.0909 0.0838 0.093
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Loa Loa (eye worm) TK protein kinase 0.0538 0.039 0.0433
Echinococcus granulosus calcium activated potassium channel 0.0327 0.0136 0.0151
Trichomonas vaginalis CAMK family protein kinase 0.0327 0.0135 0.1191
Brugia malayi Protein kinase domain containing protein 0.4597 0.529 0.587
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0288 0.0089 0.0661
Echinococcus multilocularis N chimaerin 0.035 0.0163 0.0163
Schistosoma mansoni tyrosine kinase 0.0955 0.0893 0.2192
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Plasmodium falciparum glycogen synthase kinase 3 0.1096 0.1064 1
Schistosoma mansoni nck2/grb4 0.0369 0.0187 0.0458
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Giardia lamblia Kinase, NEK 0.0231 0.002 0.0176
Onchocerca volvulus 0.0372 0.019 0.0231
Plasmodium falciparum calcium-dependent protein kinase 5 0.0525 0.0375 0.3399
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.181 0.1926 0.2138
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0969 0.091 0.101
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1486 0.1534 0.1703
Echinococcus granulosus dual specificity 0.027 0.0067 0.0075
Entamoeba histolytica cell division protein kinase 2, putative 0.0427 0.0257 0.2407
Trichomonas vaginalis CK1 family protein kinase 0.059 0.0453 0.3989
Echinococcus granulosus beta-adrenergic receptor kinase 0.0295 0.0098 0.0108
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) TK/ABL protein kinase 0.2142 0.2327 0.2582
Loa Loa (eye worm) hypothetical protein 0.071 0.0598 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0519 0.0368 0.0902
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0337 0.0148 0.0164
Brugia malayi Guanylyl cyclase protein 23 0.0231 0.002 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.2164 0.2353 0.2612
Leishmania major protein kinase, putative 0.0969 0.091 0.101
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Echinococcus multilocularis serine:threonine protein kinase N2 0.1578 0.1646 0.1646
Echinococcus multilocularis mitogen activated protein kinase 11 0.768 0.9011 0.9011
Echinococcus granulosus N chimaerin 0.035 0.0163 0.0181
Loa Loa (eye worm) TK/ROR protein kinase 0.0408 0.0233 0.0259
Trichomonas vaginalis CMGC family protein kinase 0.0969 0.091 0.802
Onchocerca volvulus Basement membrane proteoglycan homolog 0.026 0.0055 0.0048
Echinococcus granulosus protein kinase 0.0231 0.002 0.0022
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0335 0.0145 0.0161
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.181 0.1926 0.2138
Loa Loa (eye worm) TK protein kinase 0.0649 0.0524 0.0582
Schistosoma mansoni growth factor receptor-bound protein 0.0384 0.0205 0.0503
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Plasmodium falciparum casein kinase 1 0.059 0.0453 0.4147
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.019 0.0467
Echinococcus multilocularis calcium activated potassium channel 0.0327 0.0136 0.0136
Entamoeba histolytica protein kinase, putative 0.0566 0.0424 0.3979
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0158 0.0388
Echinococcus multilocularis rac serine:threonine kinase 0.033 0.014 0.014
Trichomonas vaginalis TKL family protein kinase 0.0233 0.0022 0.0197
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.4661 0.5367 0.5956
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0231 0.002 0.0176
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0356 0.0171 0.1503
Echinococcus granulosus tyrosine protein kinase Lyn 0.1182 0.1167 0.1295
Brugia malayi protein kinase C II. 0.0664 0.0543 0.0602
Leishmania major protein kinase, putative 0.0566 0.0424 0.047
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1353 0.1375 0.1525
Schistosoma mansoni tyrosine kinase 0.06 0.0466 0.1143
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0855 0.0773 0.0773
Echinococcus multilocularis casein kinase I alpha 0.059 0.0453 0.0453
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Onchocerca volvulus 0.0437 0.0269 0.0337
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Echinococcus granulosus tyrosine kinase 0.0231 0.002 0.0022
Schistosoma mansoni tyrosine kinase 0.0491 0.0334 0.082
Plasmodium vivax casein kinase 1, putative 0.059 0.0453 0.4147
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0231 0.002 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0098 0.024
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0231 0.002 0.0022
Brugia malayi putative serine/threonine kinase SADA gamma 0.0337 0.0148 0.0164
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus epidermal growth factor receptor 0.0814 0.0724 0.0803
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0231 0.002 0.0022
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.108 0.1044 0.1159
Echinococcus granulosus cyclin dependent kinase 9 0.0349 0.0162 0.0179
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1155 0.1135 0.126
Echinococcus multilocularis growth factor receptor bound protein 2 0.0369 0.0187 0.0187
Echinococcus granulosus kinase suppressor of Ras 1 0.0231 0.002 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0525 0.0375 0.0375
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.026 0.0055 0.0061
Echinococcus multilocularis 0.0805 0.0713 0.0713
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.059 0.0453 0.0503
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) TK/RYK protein kinase 0.0231 0.002 0.0022
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0231 0.002 0.0049
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1096 0.1064 1
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.002 0.0049
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1018 0.097 0.097
Echinococcus multilocularis tyrosine protein kinase shark 0.0653 0.0529 0.0529
Loa Loa (eye worm) hypothetical protein 0.0306 0.011 0.0122
Toxoplasma gondii protein kinase domain-containing protein 0.0231 0.002 0.0188
Echinococcus multilocularis serine threonine protein kinase 0.0561 0.0418 0.0418
Entamoeba histolytica protein kinase, putative 0.0526 0.0376 0.353
Brugia malayi Fibronectin type III domain containing protein 0.0601 0.0467 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Schistosoma mansoni nephrin 0.0292 0.0094 0.0231
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0231 0.002 0.002
Schistosoma mansoni tyrosine kinase 0.1263 0.1265 0.3106
Brugia malayi Protein kinase domain containing protein 0.0519 0.0368 0.0408
Schistosoma mansoni tyrosine kinase 0.0757 0.0654 0.1606
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0631 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0917 0.0847 0.094
Giardia lamblia Kinase, AGC PKA 0.0698 0.0583 0.5137
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1642 0.1722 0.1911
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi protein kinase C3,putative 0.0391 0.0213 0.0236
Entamoeba histolytica ankyrin repeat protein 0.0231 0.002 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0266 0.0062 0.0062
Brugia malayi Doublecortin family protein 0.0282 0.0082 0.0091
Trypanosoma brucei protein kinase, putative 0.0394 0.0217 0.0241
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi Protein kinase domain containing protein 0.1642 0.1722 0.1911
Echinococcus granulosus calcium dependent protein kinase 0.0362 0.0178 0.0197
Entamoeba histolytica cysteine surface protein, putative 0.0231 0.002 0.0178
Plasmodium falciparum calcium-dependent protein kinase 1 0.0525 0.0375 0.3399
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2677 0.2973 0.2973
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0062 0.0152
Loa Loa (eye worm) hypothetical protein 0.026 0.0055 0.0061
Giardia lamblia Kinase, CK1 Casein kinase 0.059 0.0453 0.3989
Schistosoma mansoni serine/threonine protein kinase 0.0491 0.0333 0.0818
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Trichomonas vaginalis STE family protein kinase 0.0216 0.0001 0.001
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica protein kinase, putative 0.0381 0.0201 0.1884
Schistosoma mansoni serine/threonine protein kinase 0.108 0.1044 0.2563
Echinococcus multilocularis dual specificity 0.027 0.0067 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Loa Loa (eye worm) AGC/PKA protein kinase 0.0698 0.0583 0.0647
Trichomonas vaginalis CK1 family protein kinase 0.059 0.0453 0.3989
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2052 0.2217 0.2461
Echinococcus granulosus tyrosine protein kinase ABL1 0.2142 0.2327 0.2582
Echinococcus granulosus NDR protein kinase 0.0519 0.0368 0.0408
Leishmania major protein kinase, putative 0.0394 0.0217 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0566 0.0424 0.104
Echinococcus granulosus serine:threonine kinase SAD 1 0.0337 0.0148 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Schistosoma mansoni protein kinase 0.0566 0.0424 0.104
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.0112 0.0988
Loa Loa (eye worm) AUR protein kinase 0.0566 0.0424 0.047
Schistosoma mansoni tyrosine protein kinase 0.0231 0.002 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.1296 0.1305 0.3202
Schistosoma mansoni protein kinase 0.2335 0.256 0.6283
Trypanosoma brucei protein kinase, putative 0.0247 0.0039 0.0044
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Schistosoma mansoni protein kinase 0.0361 0.0177 0.0434
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0736 0.063 0.0699
Loa Loa (eye worm) AUR protein kinase 0.0566 0.0424 0.047
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0327 0.0135 0.015
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0664 0.0543 0.0602
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0231 0.002 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0361 0.0177 0.0177
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0245 0.0036 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0431 0.0261 0.029
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.768 0.9011 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0427 0.0257 0.2415
Loa Loa (eye worm) AGC/PKA protein kinase 0.0698 0.0583 0.0647
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0361 0.0177 0.0196
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) RGC/RGC protein kinase 0.0231 0.002 0.0022
Echinococcus granulosus cyclin dependent kinase 0.0427 0.0257 0.0285
Brugia malayi Protein kinase domain containing protein 0.0411 0.0236 0.0262
Echinococcus multilocularis PAK box P21 Rho binding 0.0339 0.015 0.015
Onchocerca volvulus Slit protein homolog 0.0254 0.0048 0.0038
Echinococcus granulosus protein kinase c iota type 0.0747 0.0642 0.0713
Echinococcus multilocularis casein kinase I alpha 0.059 0.0453 0.0453
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0814 0.0724 0.0803
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0525 0.0375 0.0416
Brugia malayi Protein kinase domain containing protein 0.0333 0.0143 0.0158
Loa Loa (eye worm) hypothetical protein 0.0748 0.0644 0.0715
Onchocerca volvulus 0.0437 0.0269 0.0337
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0307 0.0112 0.0124
Trichomonas vaginalis AGC family protein kinase 0.0245 0.0036 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0098 0.0241
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0231 0.002 0.0022
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0216 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0794 0.07 0.0777
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Loa Loa (eye worm) hypothetical protein 0.0572 0.0431 0.0478
Echinococcus granulosus tyrosine protein kinase Fyn 0.1018 0.097 0.1077
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.0257 0.063
Entamoeba histolytica protein kinase, putative 0.0361 0.0177 0.1654
Echinococcus multilocularis calcium dependent protein kinase 0.0362 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0601 0.0467 0.0518
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0216 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0569 0.0428 0.0475
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.063 0.0501 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0525 0.0375 0.092
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1296 0.1305 0.1448
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0361 0.0177 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0276 0.0075 0.0083
Giardia lamblia Kinase, NEK 0.0268 0.0064 0.0563
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Toxoplasma gondii AGC kinase 0.0698 0.0583 0.5481
Trichomonas vaginalis AGC family protein kinase 0.0519 0.0368 0.3239
Schistosoma mansoni septate junction protein 0.026 0.0055 0.0135
Onchocerca volvulus 0.0251 0.0045 0.0033
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2164 0.2353 0.2612
Schistosoma mansoni roundabout 0.026 0.0055 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Echinococcus granulosus protein tyrosine kinase 0.359 0.4074 0.4522
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0647
Loa Loa (eye worm) TK protein kinase 0.0855 0.0773 0.0858
Entamoeba histolytica protein kinase domain containing protein 0.1096 0.1064 1
Trypanosoma brucei casein kinase I, isoform 2 0.059 0.0453 0.0503
Giardia lamblia Protein 21.1 0.0231 0.002 0.0176
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0583
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0292 0.0094 0.0094
Echinococcus granulosus protein kinase shaggy 0.1096 0.1064 0.118
Brugia malayi integrin-linked kinase 0.0231 0.002 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0246 0.0038 0.0337
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Echinococcus granulosus retinal guanylyl cyclase 2 0.0231 0.002 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis protein kinase 0.0231 0.002 0.002
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Echinococcus multilocularis MAM 0.0318 0.0124 0.0124
Schistosoma mansoni tyrosine kinase 0.0407 0.0232 0.057
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0987 0.0933 0.0933
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0394 0.0217 0.0241
Echinococcus granulosus growth factor receptor bound protein 2 0.0384 0.0205 0.0228
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Trypanosoma cruzi Protein kinase B 0.033 0.014 0.0155
Plasmodium falciparum calcium-dependent protein kinase 4 0.0525 0.0375 0.3399
Brugia malayi P38 map kinase family protein 2 0.768 0.9011 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0525 0.0375 0.0375
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0631 0.0503 0.0558
Echinococcus granulosus activin receptor type 0.3784 0.4308 0.4781
Schistosoma mansoni serine/threonine protein kinase 0.059 0.0453 0.1111
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0827 0.0739 0.0739
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2677 0.2973 0.3299
Giardia lamblia Kinase, CMGC CDK 0.0427 0.0257 0.2263
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1296 0.1305 0.1305
Echinococcus granulosus tyrosine protein kinase Src42A 0.1018 0.097 0.1077
Loa Loa (eye worm) CAMK/PIM protein kinase 0.212 0.23 0.2552
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1018 0.097 0.1077
Loa Loa (eye worm) TK protein kinase 0.0231 0.002 0.0022
Brugia malayi Protein kinase domain containing protein 0.0729 0.0621 0.069
Trypanosoma cruzi rac serine-threonine kinase, putative 0.033 0.014 0.0155
Brugia malayi Protein kinase domain containing protein 0.0736 0.063 0.0699
Brugia malayi Protein kinase domain containing protein 0.0427 0.0257 0.0285
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0411 0.0236 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.1578 0.1646 0.404
Echinococcus multilocularis 0.0217 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.034 0.0151 0.0372
Schistosoma mansoni ephrin receptor 0.0296 0.0098 0.0241
Brugia malayi Hr1 repeat family protein 0.1578 0.1646 0.1827
Onchocerca volvulus 0.0437 0.0269 0.0337
Schistosoma mansoni cell adhesion molecule 0.0292 0.0094 0.0231
Brugia malayi RhoGAP domain containing protein 0.035 0.0163 0.0181
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0744 0.0639 0.0639
Echinococcus granulosus tyrosine protein kinase 0.0231 0.002 0.0022
Schistosoma mansoni tyrosine kinase 0.06 0.0466 0.1143
Brugia malayi Tyrosine-protein kinase PR2 0.0231 0.002 0.0022
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.108 0.1044 0.1159
Onchocerca volvulus Serine\/threonine kinase homolog 0.0296 0.0098 0.0106
Echinococcus multilocularis insulin receptor 0.1263 0.1265 0.1265
Schistosoma mansoni serine/threonine protein kinase 0.0987 0.0933 0.2289
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0288 0.0089 0.0661
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0427 0.0257 0.0285
Brugia malayi Protein kinase domain containing protein 0.0296 0.0098 0.0109
Trypanosoma cruzi polo-like protein kinase, putative 0.0307 0.0112 0.0124
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.2985 0.3344 0.3711
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0652 0.0529 0.0587
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0249 0.0042 0.0047
Loa Loa (eye worm) AGC/PKG protein kinase 0.0266 0.0062 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Schistosoma mansoni protein tyrosine kinase 0.0231 0.002 0.0049
Echinococcus granulosus MAM 0.0318 0.0124 0.0138
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1017 0.0969 0.1075
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1155 0.1135 0.126
Brugia malayi p70 ribosomal S6 kinase beta 0.0644 0.0519 0.0575
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.039 0.0211 0.0234
Giardia lamblia Kinase, PLK 0.0307 0.0112 0.0988
Brugia malayi Protein kinase domain containing protein 0.1263 0.1265 0.1404
Plasmodium vivax serine/threonine kinase-1, putative 0.0969 0.091 0.853
Toxoplasma gondii CMGC kinase, CK2 family 0.0231 0.002 0.0188
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1018 0.097 0.097
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni protein kinase 0.0394 0.0217 0.0533
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.0686 0.0569 0.0632
Echinococcus multilocularis hemicentin 1 0.026 0.0055 0.0055
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0698 0.0583 0.5481
Loa Loa (eye worm) AGC/AKT protein kinase 0.0686 0.0569 0.0632
Echinococcus multilocularis tyrosine protein kinase otk 0.026 0.0055 0.0055
Brugia malayi hypothetical protein 0.0566 0.0424 0.0471
Schistosoma mansoni protein kinase 0.0394 0.0217 0.0533
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0231 0.002 0.0049
Echinococcus granulosus cGMP dependent protein kinase 0.0266 0.0062 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0601 0.0467 0.0518
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0295 0.0098 0.0108
Schistosoma mansoni atypical protein kinase C 0.0753 0.065 0.1595
Brugia malayi Protein kinase domain containing protein 0.212 0.23 0.2552
Brugia malayi hypothetical protein 0.0318 0.0124 0.0138
Brugia malayi cyclin-dependent kinase 7 homolog 0.0664 0.0542 0.0602
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.212 0.23 0.23
Trypanosoma brucei protein kinase, putative 0.1096 0.1064 0.118
Entamoeba histolytica receptor protein kinase, putative 0.0231 0.002 0.0178
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Trypanosoma cruzi cdc2-related kinase 1 0.0427 0.0257 0.0285
Loa Loa (eye worm) hypothetical protein 0.0337 0.0148 0.0164
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1295 0.1304 0.1447
Loa Loa (eye worm) thyroid receptor interactor 0.0754 0.0651 0.0722
Echinococcus granulosus mitogen activated protein kinase 11 0.768 0.9011 1
Echinococcus granulosus epidermal growth factor receptor 0.0955 0.0893 0.0991
Schistosoma mansoni protein kinase 0.1155 0.1135 0.2786
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0337 0.0148 0.0164
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0292 0.0094 0.0231
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain containing protein 0.0746 0.0641 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0707 0.0594 0.1457
Loa Loa (eye worm) hypothetical protein 0.0515 0.0362 0.0402
Echinococcus multilocularis beta adrenergic receptor kinase 0.0295 0.0098 0.0098
Schistosoma mansoni adapter molecule crk 0.0369 0.0187 0.0458
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0528 0.0379 0.042
Trichomonas vaginalis STE family protein kinase 0.0361 0.0177 0.1558
Brugia malayi protein unc-22 0.0372 0.019 0.0211
Brugia malayi Tyrosine-protein kinase abl-1 0.1053 0.1012 0.1123
Schistosoma mansoni serine/threonine protein kinase 0.0704 0.0591 0.1451
Echinococcus granulosus tyrosine protein kinase Fyn 0.1018 0.097 0.1077
Echinococcus granulosus dual specificity 0.108 0.1044 0.1159
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) serine/threonine protein kinase 0.0231 0.002 0.0022
Schistosoma mansoni ste20-related kinase 0.0337 0.0148 0.0364
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.026 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0264 0.006 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Brugia malayi protein-tyrosine kinase 0.0855 0.0773 0.0858
Schistosoma mansoni serine/threonine protein kinase 0.0934 0.0868 0.213
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0394 0.0217 0.2041
Onchocerca volvulus 0.0318 0.0124 0.0141
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.027 0.0067 0.0075
Schistosoma mansoni protein kinase 0.2164 0.2353 0.5776
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0569 0.5017
Echinococcus granulosus casein kinase I alpha 0.059 0.0453 0.0503
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0644 0.0519 0.0575
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0193 0.0475
Echinococcus granulosus protein kinase 0.0899 0.0826 0.0917
Onchocerca volvulus 0.071 0.0598 0.0783
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1096 0.1064 0.2611
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0369 0.0187 0.0207
Echinococcus granulosus mitogen activated protein kinase 14 0.768 0.9011 1
Trypanosoma cruzi cdc2-related kinase 3 0.0427 0.0257 0.0285
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0729 0.0621 0.069
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0437 0.0269 0.2518
Loa Loa (eye worm) hypothetical protein 0.0652 0.0529 0.0587
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0361 0.0177 0.0177
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Echinococcus granulosus serine:threonine protein kinase N2 0.1059 0.1019 0.1131
Echinococcus multilocularis activin receptor type 0.3784 0.4308 0.4308
Schistosoma mansoni nephrin 0.0778 0.068 0.1669
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0292 0.0094 0.0104
Schistosoma mansoni serine/threonine-protein kinase 0.033 0.014 0.0343
Entamoeba histolytica PH domain containing protein kinase, putative 0.033 0.014 0.1305
Echinococcus granulosus serine threonine protein kinase nrc 0.0288 0.0089 0.0099
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Echinococcus granulosus fibroblast growth factor receptor 4 0.1348 0.1368 0.1518
Echinococcus granulosus retinal guanylyl cyclase 2 0.0231 0.002 0.0022
Leishmania major protein kinase, putative 0.0969 0.091 0.101
Echinococcus granulosus c src tyrosine kinase 0.06 0.0466 0.0517
Schistosoma mansoni tyrosine kinase 0.1348 0.1368 0.3358
Echinococcus multilocularis dual specificity 0.027 0.0067 0.0067
Echinococcus multilocularis epidermal growth factor receptor 0.0814 0.0724 0.0724
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0883 0.0807 0.0895
Echinococcus multilocularis FL cytokine receptor 0.0231 0.002 0.002
Echinococcus multilocularis serine:threonine protein kinase 3 0.039 0.0211 0.0211
Entamoeba histolytica p21-activated kinase 0.0403 0.0228 0.2133
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Echinococcus multilocularis Immunoglobulin 0.0569 0.0428 0.0428
Brugia malayi hypothetical protein 0.0231 0.002 0.0022
Echinococcus granulosus TGF beta receptor type 1 0.0827 0.0739 0.082
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0246 0.0038 0.0038
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.035 0.0163 0.04
Loa Loa (eye worm) hypothetical protein 0.0525 0.0375 0.0416
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0288 0.0089 0.0099
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0698 0.0583 0.0647
Onchocerca volvulus 0.0426 0.0256 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0612 0.048 0.1178
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Entamoeba histolytica protein kinase, putative 0.108 0.1044 0.9818
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0525 0.0375 0.3399
Loa Loa (eye worm) hypothetical protein 0.0917 0.0847 0.094
Entamoeba histolytica protein kinase domain containing protein 0.0566 0.0424 0.3979
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0757 0.0654 0.0726
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.768 0.9011 1
Schistosoma mansoni tyrosine kinase 0.0447 0.0281 0.0689
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.026 0.0055 0.0055
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0231 0.002 0.0022
Leishmania major protein kinase A catalytic subunit isoform 1 0.0698 0.0583 0.0647
Onchocerca volvulus 0.0327 0.0135 0.0156
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0231 0.002 0.0022
Trypanosoma cruzi polo-like protein kinase, putative 0.0307 0.0112 0.0124
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Plasmodium vivax glycogen synthase kinase 3, putative 0.1096 0.1064 1
Trichomonas vaginalis CMGC family protein kinase 0.0427 0.0257 0.2263
Echinococcus granulosus defective proboscis extension response 0.0569 0.0428 0.0475
Echinococcus multilocularis cyclin dependent kinase 0.0427 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.1229 0.1225 0.1359
Echinococcus granulosus cGMP dependent protein kinase 1 0.0266 0.0062 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Loa Loa (eye worm) hypothetical protein 0.4047 0.4626 0.5133
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0406 0.0231 0.0257
Entamoeba histolytica protein kinase, putative 0.0519 0.0368 0.345
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0569 0.0428 0.105
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Leishmania major protein kinase A catalytic subunit isoform 2 0.0698 0.0583 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0143 0.035
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0292 0.0094 0.0094
Entamoeba histolytica hypothetical protein 0.0234 0.0023 0.0209
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0566 0.0424 0.3979
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0969 0.091 0.101
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0525 0.0375 0.3399
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0268 0.0064 0.0601
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Loa Loa (eye worm) TK/INSR protein kinase 0.1263 0.1265 0.1404
Echinococcus multilocularis casein kinase I alpha 0.059 0.0453 0.0453
Giardia lamblia Kinase, CAMK CAMKL 0.037 0.0187 0.165
Echinococcus multilocularis tyrosine kinase 0.0437 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.1365 0.1388 0.1541
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0148 0.0363
Trichomonas vaginalis protein kinase atn1, putative 0.0231 0.002 0.0176
Loa Loa (eye worm) SRC-1 0.1018 0.097 0.1077
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2677 0.2973 0.3299
Loa Loa (eye worm) RGC/RGC protein kinase 0.0231 0.002 0.0022
Schistosoma mansoni serine/threonine kinase 0.0519 0.0368 0.0902
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.0829 0.0742 0.0823
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus multilocularis cyclin dependent kinase 1 0.0427 0.0257 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0969 0.091 0.2234
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Echinococcus multilocularis ephrin type A receptor 4 A 0.0296 0.0098 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0566 0.0424 0.3979
Brugia malayi hypothetical protein 0.0231 0.002 0.0022
Trypanosoma cruzi casein kinase, putative 0.059 0.0453 0.0503
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0456 0.0291 0.0323
Brugia malayi Immunoglobulin I-set domain containing protein 0.0292 0.0094 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0411 0.0236 0.2084
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.0055 0.0061
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0266 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase, putative 0.0686 0.0569 0.5348
Loa Loa (eye worm) hypothetical protein 0.0437 0.0269 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.034 0.0151 0.1333
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0231 0.002 0.0178
Onchocerca volvulus Tyrosine kinase homolog 0.272 0.3024 0.4067
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0491 0.0333 0.037
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trypanosoma brucei Flagellum attachment zone protein 20 0.0231 0.002 0.0022
Brugia malayi Variant SH3 domain containing protein 0.0369 0.0187 0.0207
Echinococcus multilocularis integrin linked protein kinase 0.0231 0.002 0.002
Echinococcus multilocularis cyclin dependent kinase 7 0.0631 0.0503 0.0503
Toxoplasma gondii AGC kinase 0.0698 0.0583 0.5481
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0296 0.0098 0.0109
Leishmania major protein kinase A catalytic subunit 0.0698 0.0583 0.0647
Loa Loa (eye worm) hypothetical protein 0.0525 0.0375 0.0416
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Trypanosoma brucei cdc2-related kinase 3 0.0427 0.0257 0.0285
Brugia malayi hypothetical protein 0.0601 0.0467 0.0518
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0231 0.002 0.0022
Echinococcus granulosus Protein kinase C brain isozyme 0.0704 0.0591 0.0656
Leishmania major protein kinase, putative 0.0231 0.002 0.0022
Plasmodium falciparum calcium-dependent protein kinase 2 0.0525 0.0375 0.3399
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0337 0.0148 0.0164
Entamoeba histolytica protein kinase, putative 0.027 0.0067 0.0624
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0231 0.002 0.0022
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1348 0.1368 0.1368
Echinococcus granulosus serine:threonine protein kinase 3 0.039 0.0211 0.0234
Schistosoma mansoni hypothetical protein 0.0318 0.0124 0.0305
Trypanosoma cruzi cdc2-related kinase 3 0.0427 0.0257 0.0285
Echinococcus multilocularis casein kinase I delta 0.059 0.0453 0.0453
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0874 0.0795 0.0883
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0631 0.0503 0.0558
Brugia malayi Peroxidasin 0.0263 0.0059 0.0065
Loa Loa (eye worm) hypothetical protein 0.0757 0.0654 0.0726
Schistosoma mansoni tyrosine kinase 0.0814 0.0724 0.1776
Echinococcus granulosus hemicentin 1 0.026 0.0055 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0349 0.0162 0.0397
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2232 0.2435 0.2702
Brugia malayi Protein kinase domain containing protein 0.0407 0.0232 0.0258
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Schistosoma mansoni protein kinase 0.0361 0.0177 0.0434
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Schistosoma mansoni protein kinase 0.0895 0.0821 0.2015
Schistosoma mansoni hypothetical protein 0.0631 0.0503 0.1234
Loa Loa (eye worm) CAMK protein kinase 0.0372 0.019 0.0211
Loa Loa (eye worm) protein kinase domain-containing protein 0.0345 0.0158 0.0175
Schistosoma mansoni protein kinase C mu 0.1017 0.0969 0.2378
Entamoeba histolytica protein kinase domain containing protein 0.108 0.1044 0.9818
Schistosoma mansoni protein kinase 0.0231 0.002 0.0049
Toxoplasma gondii protein kinase 0.0231 0.002 0.0188
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0729 0.0621 0.069
Entamoeba histolytica hypothetical protein 0.0231 0.002 0.0178
Brugia malayi Protein kinase domain 0.0361 0.0177 0.0196
Echinococcus granulosus tyrosine protein kinase Fyn 0.1018 0.097 0.1077
Brugia malayi serine/threonine-protein kinase plk-2 0.0307 0.0112 0.0124
Trichomonas vaginalis AGC family protein kinase 0.0561 0.0419 0.3688
Brugia malayi Protein kinase domain containing protein 0.0736 0.063 0.0699
Echinococcus granulosus casein kinase I alpha 0.059 0.0453 0.0503
Echinococcus multilocularis receptor type guanylyl cyclase 0.0231 0.002 0.002
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0231 0.002 0.002
Echinococcus multilocularis dual specificity protein kinase clk2 0.0969 0.091 0.091
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0231 0.002 0.002
Entamoeba histolytica protein kinase, putative 0.0381 0.0201 0.1884
Schistosoma mansoni growth factor receptor-bound protein 0.0369 0.0187 0.0458
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Entamoeba histolytica PH domain containing protein kinase, putative 0.033 0.014 0.1305
Echinococcus multilocularis mitogen activated protein kinase 11 0.768 0.9011 0.9011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0292 0.0094 0.0104
Schistosoma mansoni protein kinase 0.0827 0.0739 0.1814
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0969 0.091 0.101
Loa Loa (eye worm) hypothetical protein 0.071 0.0598 0.0664
Loa Loa (eye worm) TK/FAK protein kinase 0.363 0.4123 0.4575
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0276 0.0075 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase, putative 0.0231 0.002 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.002 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.1155 0.1135 0.1135
Schistosoma mansoni cell adhesion molecule 0.0685 0.0567 0.1392
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0534 0.0386 0.0386
Echinococcus granulosus titin 0.0372 0.019 0.0211
Echinococcus granulosus tyrosine protein kinase shark 0.0653 0.0529 0.0587
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Brugia malayi Protein kinase domain containing protein 0.0519 0.0368 0.0408
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0397 0.022 0.0244
Brugia malayi serine/threonine-protein kinase PAK 7 0.2052 0.2217 0.2461
Loa Loa (eye worm) AGC/NDR protein kinase 0.0519 0.0368 0.0408
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0525 0.0375 0.3523
Loa Loa (eye worm) hypothetical protein 0.0698 0.0583 0.0647
Echinococcus multilocularis slit 2 protein 0.0254 0.0048 0.0048
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0349 0.0162 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0698 0.0583 0.1431
Schistosoma mansoni hypothetical protein 0.0231 0.002 0.0049
Echinococcus multilocularis tyrosine protein kinase csk 0.0231 0.002 0.002
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0525 0.0375 0.0416
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.0269 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus hypothetical protein 0.0805 0.0713 0.0792
Brugia malayi Raf kinase 0.0231 0.002 0.0022
Onchocerca volvulus 0.0598 0.0463 0.0599
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0234 0.0023 0.0209
Trichomonas vaginalis CAMK family protein kinase 0.0337 0.0148 0.1304
Giardia lamblia Kinase, CMGC CDK 0.0427 0.0257 0.2263
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0062 0.0152
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2335 0.256 0.256
Echinococcus multilocularis protein tyrosine kinase 0.359 0.4074 0.4074
Loa Loa (eye worm) TK protein kinase 0.1525 0.1582 0.1755
Loa Loa (eye worm) TK/ACK protein kinase 0.0231 0.002 0.0022
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0231 0.002 0.0022
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0519 0.0368 0.0902
Brugia malayi C-terminal src kinase protein 1 0.0231 0.002 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Echinococcus granulosus TGF-beta receptor type-1 0.0827 0.0739 0.082
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0566 0.0424 0.387
Loa Loa (eye worm) hypothetical protein 0.0231 0.002 0.0022
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0231 0.002 0.0178
Brugia malayi Fes/CIP4 homology domain containing protein 0.0754 0.0651 0.0722
Loa Loa (eye worm) TK/DDR protein kinase 0.0306 0.011 0.0122
Toxoplasma gondii casein kinase I 0.059 0.0453 0.4257
Brugia malayi STE20-like kinase MST 0.039 0.0211 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1348 0.1368 0.1518
Trichomonas vaginalis STE family protein kinase 0.0361 0.0177 0.1558
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0647
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0491 0.0333 0.0333
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0231 0.002 0.0022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0698 0.0583 0.0583
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0519 0.0368 0.0368
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0794 0.07 0.07
Schistosoma mansoni tyrosine kinase 0.0231 0.002 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0698 0.0583 0.1431
Trichomonas vaginalis AGC family protein kinase 0.0519 0.0368 0.3239
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0639 0.0512 0.0512
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.027 0.0067 0.0634
Trichomonas vaginalis TK family protein kinase 0.0231 0.002 0.0176
Entamoeba histolytica serine/threonine kinase, putative 0.0231 0.002 0.0178
Echinococcus multilocularis cyclin dependent kinase 9 0.0349 0.0162 0.0162
Schistosoma mansoni protein kinase 0.0899 0.0826 0.2028
Brugia malayi Prion-like- 0.026 0.0055 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.002 0.0176
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0427 0.0257 0.0285
Echinococcus granulosus tyrosine protein kinase csk 0.0231 0.002 0.0022
Echinococcus granulosus casein kinase i 0.059 0.0453 0.0503
Leishmania major hypothetical protein, conserved 0.0231 0.002 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Brugia malayi Casein kinase II, alpha chain 0.0231 0.002 0.0022
Loa Loa (eye worm) protein kinase domain-containing protein 0.0231 0.002 0.0022
Trypanosoma brucei aurora B kinase 0.0566 0.0424 0.047
Echinococcus multilocularis neuroglian 0.0746 0.0641 0.0641
Entamoeba histolytica PH domain containing protein kinase, putative 0.074 0.0634 0.5955
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0231 0.002 0.0188
Brugia malayi Protein kinase domain containing protein 0.0437 0.0269 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.0427 0.0257 0.2263
Entamoeba histolytica tyrosine kinase, putative 0.0231 0.002 0.0178
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0231 0.002 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0177
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.002 0.0178
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0337 0.0148 0.0164
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1018 0.097 0.097
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0231 0.002 0.002
Echinococcus multilocularis protein kinase shaggy 0.1096 0.1064 0.1064
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.0067 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0231 0.002 0.0176
Loa Loa (eye worm) hypothetical protein 0.071 0.0598 0.0664
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0519 0.0368 0.0408
Echinococcus multilocularis tyrosine protein kinase Blk 0.0855 0.0773 0.0773
Plasmodium vivax calcium-dependent protein kinase, putative 0.0525 0.0375 0.3399
Brugia malayi Protein kinase domain containing protein 0.0231 0.002 0.0022
Echinococcus granulosus cyclin dependent kinase 9 0.0381 0.0201 0.0223
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0246 0.0038 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.002 0.0176
Echinococcus granulosus integrin linked protein kinase 0.0231 0.002 0.0022
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0394 0.0217 0.0241
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0394 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0369 0.0187 0.0207
Plasmodium vivax protein kinase, putative 0.0246 0.0038 0.0177

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 1 uM In vitro inhibitory activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) ChEMBL. 1712395
IC50 (binding) > 1 uM In vitro inhibitory activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) ChEMBL. 1712395
Inhibition (binding) = 96 % In vitro inhibitory activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) at a concentration of 10 ug/mL. ChEMBL. 1712395
Inhibition (binding) = 96 % In vitro inhibitory activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) at a concentration of 10 ug/mL. ChEMBL. 1712395

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.