Detailed information for compound 1228098

Basic information

Technical information
  • TDR Targets ID: 1228098
  • Name: 3-[2-(4-cyclohexylpiperazin-1-yl)-2-oxoethyl] -6-pyrrolidin-1-ylsulfonyl-1,3-benzoxazol-2-o ne
  • MW: 476.589 | Formula: C23H32N4O5S
  • H donors: 0 H acceptors: 4 LogP: 2.11 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCN(CC1)C1CCCCC1)Cn1c(=O)oc2c1ccc(c2)S(=O)(=O)N1CCCC1
  • InChi: 1S/C23H32N4O5S/c28-22(25-14-12-24(13-15-25)18-6-2-1-3-7-18)17-27-20-9-8-19(16-21(20)32-23(27)29)33(30,31)26-10-4-5-11-26/h8-9,16,18H,1-7,10-15,17H2
  • InChiKey: JNDVSXYHEKFJMB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[2-(4-cyclohexylpiperazin-1-yl)-2-oxo-ethyl]-6-pyrrolidin-1-ylsulfonyl-1,3-benzoxazol-2-one
  • 3-[2-(4-cyclohexyl-1-piperazinyl)-2-oxoethyl]-6-1-pyrrolidinylsulfonyl-1,3-benzoxazol-2-one
  • 3-[2-(4-cyclohexylpiperazin-1-yl)-2-keto-ethyl]-6-pyrrolidin-1-ylsulfonyl-1,3-benzoxazol-2-one
  • MLS000523090
  • SMR000128355

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0442 0.1114 0.1588
Echinococcus granulosus tyrosine protein kinase Blk 0.0325 0.0727 0.1036
Trichomonas vaginalis AGC family protein kinase 0.0466 0.1195 0.4987
Echinococcus granulosus Protein kinase C brain isozyme 0.0702 0.1981 0.2822
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0124 0.0156
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0118 0.0037 0.0014
Echinococcus multilocularis roundabout 2 0.0114 0.0024 0.0034
Loa Loa (eye worm) hypothetical protein 0.0162 0.0183 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0838 0.1175
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0244 0.0458 0.1803
Plasmodium falciparum calcium-dependent protein kinase 3 0.0178 0.0237 0.1643
Onchocerca volvulus 0.0219 0.0373 0.0481
Schistosoma mansoni tyrosine kinase 0.0908 0.2664 0.3783
Brugia malayi C1-like domain containing protein 0.0541 0.1444 0.1424
Echinococcus multilocularis serine:threonine protein kinase 0.0302 0.0649 0.0925
Echinococcus granulosus neuroglian 0.0114 0.0024 0.0034
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0228 0.0402 0.0573
Echinococcus multilocularis PAK box P21 Rho binding 0.0176 0.0232 0.033
Echinococcus granulosus dual specificity 0.0198 0.0302 0.0431
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0328 0.0447
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0219 0.0373 0.0512
Entamoeba histolytica PH domain containing protein kinase, putative 0.0449 0.1138 0.4718
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0723 0.2051 0.2032
Brugia malayi Muscleblind-like protein 0.0153 0.0155 0.0132
Brugia malayi Furin-like cysteine rich region family protein 0.1139 0.3431 0.3415
Brugia malayi RhoGAP domain containing protein 0.0195 0.0294 0.0271
Echinococcus granulosus RNA directed DNA polymerase 0.0133 0.0087 0.0123
Schistosoma mansoni protein kinase 0.0296 0.063 0.0878
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.1353 0.1911
Echinococcus granulosus tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0358 0.0836 0.1192
Echinococcus multilocularis casein kinase I delta 0.0243 0.0454 0.0646
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0249 0.0473 0.0674
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0679 0.1903 0.2712
Schistosoma mansoni serine/threonine protein kinase 0.037 0.0876 0.123
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0219 0.0373 0.035
Onchocerca volvulus Serine\/threonine kinase homolog 0.0227 0.0402 0.0522
Entamoeba histolytica protein kinase domain containing protein 0.0159 0.0173 0.058
Plasmodium falciparum protein kinase, putative 0.0159 0.0173 0.0999
Echinococcus granulosus myotubularin protein 13 0.0143 0.012 0.0171
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0359 0.0838 0.0816
Loa Loa (eye worm) AUR protein kinase 0.0381 0.0912 0.0891
Loa Loa (eye worm) hypothetical protein 0.0346 0.0796 0.0774
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0417 0.1033 0.1012
Entamoeba histolytica cell division protein kinase 2, putative 0.0359 0.0838 0.3433
Loa Loa (eye worm) hypothetical protein 0.0256 0.0498 0.0475
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0454 0.0627
Loa Loa (eye worm) CDC7 protein kinase 0.0139 0.0107 0.0084
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0187 0.0268 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0448 0.0618
Loa Loa (eye worm) hypothetical protein 0.0178 0.0237 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0476 0.1226 0.173
Brugia malayi Protein kinase domain containing protein 0.0593 0.1618 0.1598
Schistosoma mansoni protein kinase 0.0679 0.1903 0.2697
Echinococcus multilocularis epidermal growth factor receptor 0.1139 0.3431 0.4888
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1338 0.4095 0.4081
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0328 0.1284
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1036 0.309 0.3073
Loa Loa (eye worm) TK protein kinase 0.0325 0.0727 0.0705
Trypanosoma cruzi polo-like protein kinase, putative 0.0817 0.2362 1
Toxoplasma gondii CMGC kinase, CK2 family 0.0296 0.063 0.255
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0159 0.0173 0.0401
Onchocerca volvulus 0.0489 0.1271 0.1767
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0494 0.1287 0.5269
Brugia malayi Protein kinase domain containing protein 0.0466 0.1195 0.1174
Brugia malayi ephrin receptor 1 precursor 0.0188 0.0271 0.0248
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0102 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0359 0.0838 0.3461
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.036 0.0493
Brugia malayi Sex muscle abnormal protein 5 0.0139 0.0109 0.0085
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0102 0.0146
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0162 0.0183 0.0241
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0139 0.0109 0.0085
Loa Loa (eye worm) hypothetical protein 0.0125 0.006 0.0037
Schistosoma mansoni protein kinase 0.0575 0.1556 0.22
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0212 0.0349 0.0326
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Entamoeba histolytica protein kinase domain containing protein 0.0343 0.0786 0.3212
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0219 0.0373 0.0512
Loa Loa (eye worm) AGC/NDR protein kinase 0.0442 0.1114 0.1093
Entamoeba histolytica protein kinase 2, putative 0.043 0.1074 0.4443
Brugia malayi Protein kinase domain containing protein 0.0159 0.0174 0.015
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0359 0.0838 0.3318
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0268 0.0361
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0448 0.1794
Loa Loa (eye worm) hypothetical protein 0.0313 0.0686 0.0664
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.043 0.1074 1
Loa Loa (eye worm) hypothetical protein 0.0214 0.0358 0.0335
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0139 0.0109 0.0134
Loa Loa (eye worm) TK/EGFR protein kinase 0.1139 0.3431 0.3415
Schistosoma mansoni diacylglycerol kinase theta 0.0124 0.0056 0.0059
Echinococcus multilocularis tyrosine protein kinase 0.0373 0.0885 0.1261
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0205 0.0328 0.1083
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0249 0.0473 0.0674
Echinococcus granulosus nervana 2 0.0358 0.0836 0.1192
Loa Loa (eye worm) hypothetical protein 0.0206 0.033 0.0307
Brugia malayi casein kinase 1, delta 0.0243 0.0454 0.0431
Loa Loa (eye worm) raf kinase 0.0124 0.0056 0.0033
Echinococcus multilocularis glycine receptor subunit beta 0.0219 0.0373 0.0532
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0205 0.0328 0.108
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Echinococcus multilocularis NCK adaptor protein 0.0139 0.0109 0.0155
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0241 0.0448 0.1607
Echinococcus multilocularis mitogen activated protein kinase 11 0.0494 0.1287 0.1833
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0219 0.0373 0.0532
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0494 0.1287 0.5286
Schistosoma mansoni tyrosine kinase 0.0192 0.0285 0.0385
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0159 0.0174 0.0247
Echinococcus multilocularis titin 0.0141 0.0115 0.0163
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0514 0.1353 0.1928
Onchocerca volvulus 0.0159 0.0174 0.0195
Brugia malayi diacylglycerol kinase 0.0124 0.0056 0.0033
Echinococcus multilocularis serine:threonine protein kinase N2 0.0596 0.1628 0.2319
Echinococcus granulosus protein kinase C gamma type 0.0579 0.157 0.2237
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0114 0.0024 0.0034
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0514 0.1355 0.1931
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Entamoeba histolytica protein kinase domain containing protein 0.0273 0.0554 0.2216
Schistosoma mansoni protein kinase 0.0159 0.0173 0.0225
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0144 0.0124 0.01
Leishmania major protein kinase A catalytic subunit isoform 2 0.0205 0.0328 0.1083
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0448 0.1794
Echinococcus multilocularis tyrosine protein kinase Abl 0.0227 0.0399 0.0568
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0245 0.046 0.0437
Echinococcus granulosus NCK adaptor protein 0.0139 0.0109 0.0155
Entamoeba histolytica protein kinase, putative 0.0178 0.0237 0.0857
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0244 0.0458 0.1647
Brugia malayi Protein kinase domain containing protein 0.0359 0.0838 0.0816
Brugia malayi Stress-activated protein kinase jnk-1 0.0846 0.2457 0.2439
Loa Loa (eye worm) hypothetical protein 0.0186 0.0263 0.024
Trichomonas vaginalis STE family protein kinase 0.0249 0.0473 0.1903
Schistosoma mansoni neurotransmitter gated ion channel 0.0118 0.0037 0.0032
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0159 0.0174 0.0584
Trypanosoma cruzi polo-like protein kinase, putative 0.0817 0.2362 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0494 0.1287 0.1266
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0178 0.0237 0.0338
Brugia malayi SH2 domain containing protein 0.0365 0.086 0.0838
Loa Loa (eye worm) hypothetical protein 0.0128 0.007 0.0047
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0178 0.0237 0.0214
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0219 0.0373 0.035
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0393 0.0953 0.1357
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0178 0.0237 0.1975
Brugia malayi hypothetical protein 0.0186 0.0263 0.024
Loa Loa (eye worm) hypothetical protein 0.0302 0.0649 0.0627
Leishmania major casein kinase, putative 0.0243 0.0454 0.1633
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.037 0.0876 0.3475
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0219 0.0373 0.035
Echinococcus granulosus tyrosine protein kinase HCK 0.0254 0.0489 0.0697
Onchocerca volvulus 0.0141 0.0115 0.0111
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Echinococcus granulosus protein kinase c epsilon type 0.057 0.1539 0.2193
Brugia malayi hypothetical protein 0.0297 0.0632 0.0609
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0633 0.175 0.2493
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0219 0.0373 0.0532
Echinococcus granulosus insulin receptor 0.0908 0.2664 0.3796
Schistosoma mansoni serine/threonine protein kinase 0.06 0.164 0.2321
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0723 0.2051 0.2922
Schistosoma mansoni vesicular amine transporter 0.0162 0.0183 0.0241
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0297 0.0632 0.09
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0178 0.0237 0.0338
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0325 0.0727 0.1036
Echinococcus granulosus CDC7 cell division cycle 7 0.0139 0.0107 0.0153
Schistosoma mansoni unc-13 (munc13) 0.0128 0.007 0.0079
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0114 0.0024 0.0034
Onchocerca volvulus 0.0156 0.0165 0.0183
Echinococcus multilocularis tyrosine protein kinase HCK 0.0254 0.0489 0.0697
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0114 0.0024 0.0034
Echinococcus granulosus expressed protein 0.0131 0.0081 0.0115
Brugia malayi Kinase associated domain 1 family protein 0.0174 0.0223 0.0199
Loa Loa (eye worm) AGC/PKA protein kinase 0.0205 0.0328 0.0305
Trichomonas vaginalis CK1 family protein kinase 0.0243 0.0454 0.182
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0198 0.0302 0.097
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0178 0.0237 0.0804
Trypanosoma cruzi casein kinase, putative 0.0243 0.0454 0.1633
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0243 0.0454 0.0431
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.046 0.1846
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0195 0.0294 0.0399
Brugia malayi protein kinase C II. 0.057 0.1539 0.1519
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0541 0.1444 0.1424
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0297 0.0632 0.09
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1114 0.157
Brugia malayi protein-tyrosine kinase 0.0325 0.0727 0.0705
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0302 0.041
Trypanosoma brucei cdc2-related kinase 1 0.0359 0.0838 0.3308
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0846 0.2457 0.2439
Schistosoma mansoni hypothetical protein 0.0174 0.0223 0.0297
Schistosoma mansoni serine/threonine-protein kinase 0.0449 0.1138 0.1603
Brugia malayi RhoGAP domain containing protein 0.0124 0.0056 0.0033
Schistosoma mansoni tyrosine kinase 0.0159 0.0174 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0268 0.0361
Onchocerca volvulus 0.047 0.1207 0.1676
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0219 0.0373 0.0532
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0195 0.0294 0.0419
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0198 0.0302 0.0967
Loa Loa (eye worm) SRC-1 0.0393 0.0953 0.0931
Schistosoma mansoni protein kinase C 0.0128 0.007 0.0079
Brugia malayi Protein kinase domain containing protein 0.0159 0.0174 0.015
Brugia malayi Cation transporter family protein 0.0219 0.0373 0.035
Onchocerca volvulus 0.0219 0.0373 0.0481
Schistosoma mansoni protein kinase 0.0262 0.0515 0.0715
Giardia lamblia Kinase, STE STE20 0.0249 0.0473 0.1718
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0128 0.007 0.01
Entamoeba histolytica PH domain containing protein kinase, putative 0.0225 0.0392 0.1521
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0162 0.0183 0.0241
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0118 0.0037 0.0032
Echinococcus granulosus epidermal growth factor receptor 0.0769 0.2201 0.3137
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0227 0.0402 0.0572
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0514 0.1355 0.1931
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0476 0.1226 0.1747
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus granulosus titin 0.0141 0.0115 0.0163
Echinococcus multilocularis myotubularin protein 13 0.0143 0.012 0.0171
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Giardia lamblia Kinase, CMGC GSK 0.0343 0.0786 0.3092
Echinococcus multilocularis casein kinase I delta 0.0243 0.0454 0.0646
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Loa Loa (eye worm) hypothetical protein 0.0143 0.012 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0107 0.0341
Echinococcus multilocularis expressed protein 0.0131 0.0081 0.0115
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0208 0.0338 0.0315
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0178 0.0237 0.0682
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0244 0.0458 0.1652
Echinococcus multilocularis myosin iiia 0.0244 0.0458 0.0652
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0198 0.0302 0.0279
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Echinococcus multilocularis nervana 2 0.0358 0.0836 0.1192
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0365 0.086 0.1225
Echinococcus multilocularis protein kinase c epsilon type 0.057 0.1539 0.2193
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Entamoeba histolytica hypothetical protein 0.0124 0.0056 0.0081
Echinococcus granulosus aurora kinase A 0.0381 0.0912 0.13
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Echinococcus multilocularis serotonin receptor 0.0139 0.0106 0.0151
Entamoeba histolytica protein kinase, putative 0.037 0.0876 0.3597
Echinococcus multilocularis Diacylglycerol kinase theta 0.0124 0.0056 0.008
Loa Loa (eye worm) TK/INSR protein kinase 0.0908 0.2664 0.2647
Brugia malayi cell division control protein 2 homolog 0.0359 0.0838 0.0816
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0227 0.0402 0.0572
Loa Loa (eye worm) hypothetical protein 0.0205 0.0328 0.0305
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.037 0.0876 0.3486
Echinococcus granulosus growth factor receptor bound protein 2 0.0139 0.0109 0.0155
Schistosoma mansoni protein kinase 0.0575 0.1556 0.22
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Loa Loa (eye worm) hypothetical protein 0.0299 0.0639 0.0617
Brugia malayi Cam kinase protein 1 0.0178 0.0237 0.0214
Brugia malayi serine/threonine-protein kinase PAK 7 0.0738 0.2099 0.208
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1114 0.157
Loa Loa (eye worm) hypothetical protein 0.0144 0.0123 0.01
Schistosoma mansoni serine/threonine protein kinase 0.2218 0.7018 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0114 0.0024 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Brugia malayi protein unc-22 0.0141 0.0115 0.0091
Echinococcus granulosus activin receptor type 0.0159 0.0173 0.0246
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0102 0.0146
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0241 0.0448 0.1602
Echinococcus multilocularis RNA directed DNA polymerase 0.0133 0.0087 0.0123
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2218 0.7018 0.7011
Echinococcus multilocularis Glutaredoxin protein 5 0.0358 0.0836 0.1192
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.037 0.0876 0.3486
Echinococcus granulosus casein kinase I alpha 0.0243 0.0454 0.0646
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2218 0.7018 1
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0723 0.2051 0.2922
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.0649 0.2654
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0381 0.0912 0.13
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0219 0.0373 0.0532
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.037 0.0876 0.0855
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0144 0.0124 0.0412
Entamoeba histolytica protein kinase, putative 0.0153 0.0154 0.0501
Loa Loa (eye worm) hypothetical protein 0.0346 0.0796 0.0774
Trichomonas vaginalis CMGC family protein kinase 0.0343 0.0786 0.3241
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0343 0.0786 0.3092
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0219 0.0373 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.0236 0.089
Schistosoma mansoni tyrosine kinase 0.0393 0.0953 0.1339
Echinococcus granulosus roundabout 2 0.0114 0.0024 0.0034
Toxoplasma gondii AGC kinase 0.0205 0.0328 0.1208
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0128 0.007 0.01
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2218 0.7018 0.7011
Loa Loa (eye worm) hypothetical protein 0.0906 0.2659 0.2642
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0215 0.036 0.1224
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0738 0.2099 0.208
Entamoeba histolytica protein kinase, putative 0.0198 0.0302 0.1136
Trypanosoma brucei protein kinase, putative 0.0159 0.0173 0.0401
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Brugia malayi excitatory GABA receptor EXP-1A 0.0219 0.0373 0.035
Entamoeba histolytica protein kinase, putative 0.037 0.0876 0.3597
Onchocerca volvulus 0.0219 0.0373 0.0481
Trichomonas vaginalis STE family protein kinase 0.0249 0.0473 0.1903
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0633 0.175 0.2493
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0143 0.0121 0.0356
Echinococcus multilocularis epidermal growth factor receptor 0.0769 0.2201 0.3137
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0237 0.0318
Echinococcus granulosus tyrosine protein kinase Src64B 0.0393 0.0953 0.1357
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Echinococcus granulosus protein kinase c iota type 0.0843 0.2448 0.3488
Schistosoma mansoni ephrin receptor 0.0302 0.0648 0.0904
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0296 0.063 0.0608
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0205 0.0328 0.1083
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0492 0.1282 0.1261
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0244 0.0458 0.1803
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0139 0.0109 0.0085
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Loa Loa (eye worm) hypothetical protein 0.0287 0.0601 0.0578
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0219 0.0373 0.035
Loa Loa (eye worm) hypothetical protein 0.0186 0.0263 0.024
Loa Loa (eye worm) AGC/PKN protein kinase 0.0596 0.1628 0.1608
Onchocerca volvulus 0.0146 0.013 0.0133
Trichomonas vaginalis AGC family protein kinase 0.0485 0.1259 0.526
Loa Loa (eye worm) hypothetical protein 0.0153 0.0155 0.0132
Brugia malayi Protein kinase domain containing protein 0.0131 0.0081 0.0057
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0133 0.0088 0.0126
Trypanosoma brucei protein kinase, putative 0.0241 0.0448 0.1602
Echinococcus granulosus cyclin dependent kinase 0.0359 0.0838 0.1194
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0162 0.0183 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Echinococcus multilocularis cyclin dependent kinase 0.0359 0.0838 0.1194
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0244 0.0458 0.1652
Onchocerca volvulus 0.1049 0.3135 0.4437
Trypanosoma cruzi cdc2-related kinase 1 0.0359 0.0838 0.3318
Echinococcus granulosus calcium activated potassium channel 0.0245 0.046 0.0655
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0332 0.075 0.1069
Echinococcus granulosus neuroglian 0.0208 0.0336 0.0479
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0227 0.0402 0.0379
Brugia malayi Protein kinase domain containing protein 0.037 0.0876 0.0855
Onchocerca volvulus 0.0159 0.0174 0.0195
Schistosoma mansoni tyrosine kinase 0.0769 0.2201 0.3122
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Schistosoma mansoni protein kinase 0.0492 0.1282 0.1809
Loa Loa (eye worm) AUR protein kinase 0.0381 0.0912 0.0891
Entamoeba histolytica protein kinase, putative 0.0196 0.0296 0.1107
Schistosoma mansoni tyrosine kinase 0.0227 0.0399 0.0548
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0268 0.0361
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0241 0.0448 0.174
Giardia lamblia Kinase, CK1 Casein kinase 0.0243 0.0454 0.1633
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0219 0.0373 0.0532
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0359 0.0838 0.0816
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0358 0.0836 0.1192
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus multilocularis twitchin 0.0117 0.0035 0.005
Loa Loa (eye worm) TK protein kinase 0.0294 0.0622 0.06
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0243 0.0454 0.0431
Brugia malayi Protein kinase domain containing protein 0.0159 0.0174 0.015
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0241 0.0448 0.1607
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0343 0.0786 0.112
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0448 0.1794
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0215 0.036 0.122
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Echinococcus multilocularis growth factor receptor bound protein 2 0.0139 0.0109 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Onchocerca volvulus 0.0465 0.119 0.1651
Echinococcus granulosus raf serine:threonine protein kinase 0.0211 0.0347 0.0494
Brugia malayi Temporarily assigned gene name protein 59 0.0156 0.0165 0.0142
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0159 0.0173 0.0517
Echinococcus multilocularis casein kinase I alpha 0.0243 0.0454 0.0646
Entamoeba histolytica p21-activated kinase 0.0268 0.0537 0.2142
Toxoplasma gondii AGC kinase 0.0205 0.0328 0.1208
Echinococcus multilocularis nAChR subunit 0.0118 0.0037 0.0053
Echinococcus granulosus tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0081 0.0095
Plasmodium falciparum casein kinase 1 0.0243 0.0454 0.3806
Schistosoma mansoni tyrosine kinase 0.0908 0.2664 0.3783
Schistosoma mansoni serine/threonine protein kinase 0.026 0.051 0.0707
Trichomonas vaginalis AGC family protein kinase 0.0381 0.0912 0.3778
Loa Loa (eye worm) hypothetical protein 0.0299 0.0641 0.0619
Brugia malayi serine/threonine kinase 12 0.0381 0.0912 0.0891
Brugia malayi Protein kinase domain containing protein 0.0262 0.0515 0.0493
Echinococcus multilocularis muscleblind protein 0.0153 0.0155 0.0221
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0154 0.0199
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0219 0.0373 0.035
Entamoeba histolytica protein kinase, putative 0.0254 0.0489 0.1938
Loa Loa (eye worm) CAMK protein kinase 0.0141 0.0115 0.0091
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0205 0.0328 0.108
Echinococcus granulosus fibroblast growth factor receptor 4 0.0633 0.175 0.2493
Echinococcus multilocularis ephrin type A receptor 4 A 0.0302 0.0648 0.0923
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Schistosoma mansoni protein kinase 0.0249 0.0473 0.0654
Onchocerca volvulus 0.0219 0.0373 0.0481
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0219 0.0373 0.035
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0215 0.036 0.122
Echinococcus granulosus protein kinase c eta type 0.0124 0.0056 0.008
Plasmodium vivax protein kinase Crk2 0.0359 0.0838 0.774
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis serine:threonine protein kinase N2 0.0154 0.0159 0.0226
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0381 0.0912 0.8452
Brugia malayi Protein kinase domain containing protein 0.2218 0.7018 0.7011
Echinococcus granulosus serine:threonine protein kinase N2 0.0154 0.0159 0.0226
Brugia malayi Protein kinase domain 0.0249 0.0473 0.045
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0621 0.1709 0.2435
Echinococcus multilocularis 0.0322 0.0717 0.1022
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Echinococcus granulosus NDR protein kinase 0.0442 0.1114 0.1588
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Brugia malayi Protein kinase domain containing protein 0.0215 0.036 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0237 0.0896
Echinococcus multilocularis neuroglian 0.0114 0.0024 0.0034
Echinococcus multilocularis mitogen activated protein kinase 11 0.0494 0.1287 0.1833
Echinococcus granulosus N chimaerin 0.0195 0.0294 0.0419
Echinococcus multilocularis tyrosine protein kinase Blk 0.0325 0.0727 0.1036
Loa Loa (eye worm) hypothetical protein 0.0159 0.0174 0.015
Trypanosoma brucei Casein kinase II 0.0296 0.063 0.2399
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0347 0.0474
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1481 0.457 0.6511
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0633 0.175 0.1731
Brugia malayi protein kinase C3,putative 0.0473 0.1216 0.1195
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0554 0.077
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0476 0.1226 0.1747
Trichomonas vaginalis CMGC family protein kinase 0.0359 0.0838 0.3461
Echinococcus multilocularis protein kinase shaggy 0.0343 0.0786 0.112
Brugia malayi Variant SH3 domain containing protein 0.0139 0.0109 0.0085
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2218 0.7018 1
Entamoeba histolytica diacylglycerol kinase, putative 0.0124 0.0056 0.0081
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1281 0.3903 0.5561
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0302 0.0649 0.0627
Schistosoma mansoni atypical protein kinase C 0.0863 0.2516 0.3571
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0153 0.0154 0.022
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0133 0.0087 0.0123
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0205 0.0328 0.2848
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0178 0.0237 0.1975
Echinococcus multilocularis casein kinase ii subunit alpha 0.0296 0.063 0.0898
Brugia malayi hypothetical protein 0.0116 0.0031 0.0007
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0273 0.0554 0.079
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0159 0.0173 0.0402
Plasmodium falciparum serine/threonine protein kinase 0.0131 0.0081 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Toxoplasma gondii aurora kinase 0.0381 0.0912 0.3806
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0187 0.0268 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0817 0.2362 0.2344
Onchocerca volvulus 0.0159 0.0174 0.0195
Loa Loa (eye worm) TK/ABL protein kinase 0.0159 0.0174 0.015
Echinococcus granulosus mitogen activated protein kinase 3 0.0241 0.0448 0.0638
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0417 0.1031 0.9592
Brugia malayi Protein kinase domain containing protein 0.0373 0.0885 0.0863
Trichomonas vaginalis AGC family protein kinase 0.0466 0.1195 0.4987
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0359 0.0838 0.3476
Brugia malayi probable protein kinase 0.0371 0.0878 0.0857
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0118 0.0037 0.0014
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0124 0.0056 0.0033
Loa Loa (eye worm) GABA receptor subunit 0.0118 0.0037 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0219 0.0373 0.0532
Echinococcus multilocularis 0.0144 0.0123 0.0175
Loa Loa (eye worm) hypothetical protein 0.0156 0.0165 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0762 0.1066
Giardia lamblia Kinase, CDC7 0.0139 0.0107 0.0116
Brugia malayi Protein kinase domain containing protein 0.0566 0.1528 0.1508
Echinococcus multilocularis mitogen activated protein kinase 14 0.0494 0.1287 0.1833
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0932 0.2743 0.3909
Echinococcus multilocularis dual specificity protein kinase clk2 0.0215 0.036 0.0513
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.0431 0.5
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0817 0.2362 0.3366
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0241 0.0448 0.1607
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0404 0.0988 0.0967
Loa Loa (eye worm) TK/FER protein kinase 0.0365 0.086 0.0838
Trypanosoma brucei polo-like protein kinase 0.0817 0.2362 0.9968
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Entamoeba histolytica PH domain containing protein kinase, putative 0.0449 0.1138 0.4718
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0131 0.0081 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0268 0.0361
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Entamoeba histolytica protein kinase domain containing protein 0.0343 0.0786 0.3212
Schistosoma mansoni neuroglian 0.0114 0.0024 0.0013
Echinococcus granulosus tyrosine protein kinase Lyn 0.0465 0.119 0.1695
Echinococcus granulosus serine:threonine protein kinase N2 0.0596 0.1628 0.2319
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1281 0.3903 0.5561
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0299 0.0641 0.0913
Brugia malayi Protein kinase domain containing protein 0.0286 0.0596 0.0574
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0359 0.0838 0.3318
Echinococcus granulosus serine:threonine protein kinase 0.0302 0.0649 0.0925
Plasmodium falciparum glycogen synthase kinase 3 0.0343 0.0786 0.7131
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0172 0.0216 0.0594
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Onchocerca volvulus 0.0214 0.0358 0.0459
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Echinococcus multilocularis serine:threonine protein kinase N2 0.0442 0.1114 0.1588
Brugia malayi Protein kinase domain containing protein 0.0245 0.046 0.0437
Echinococcus multilocularis dual specificity 0.0198 0.0302 0.0431
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.3114 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0238 0.0437 0.0623
Echinococcus granulosus tyrosine protein kinase Srms 0.0159 0.0174 0.0247
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus granulosus casein kinase I gamma 0.0286 0.0596 0.0849
Brugia malayi Temporarily assigned gene name protein 59 0.0432 0.1081 0.106
Echinococcus multilocularis cyclin dependent kinase 5 0.0359 0.0838 0.1194
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0442 0.1114 0.1588
Entamoeba histolytica protein kinase, putative 0.0131 0.0081 0.0187
Loa Loa (eye worm) thyroid receptor interactor 0.0153 0.0155 0.0131
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.037 0.0876 0.3486
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0144 0.0124 0.01
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.043 0.1074 1
Brugia malayi hypothetical protein 0.0159 0.0174 0.015
Entamoeba histolytica protein kinase, putative 0.0343 0.0786 0.3212
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0035 0.0029
Brugia malayi SH2 domain containing protein 0.0159 0.0174 0.015
Echinococcus multilocularis casein kinase i 0.0243 0.0454 0.0646
Plasmodium vivax calcium-dependent protein kinase, putative 0.0178 0.0237 0.1975
Schistosoma mansoni serine/threonine-protein kinase 0.0449 0.1138 0.1603
Echinococcus multilocularis raf serine:threonine protein kinase 0.0211 0.0347 0.0494
Schistosoma mansoni hypothetical protein 0.0156 0.0165 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0328 0.0447
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0393 0.0953 0.1357
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0769 0.2201 0.3137
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Brugia malayi p70 ribosomal S6 kinase beta 0.08 0.2305 0.2287
Schistosoma mansoni hypothetical protein 0.0124 0.0056 0.0059
Brugia malayi Pleckstrin Homology Domain 0.0143 0.012 0.0097
Schistosoma mansoni tyrosine kinase 0.0769 0.2201 0.3122
Echinococcus granulosus glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Echinococcus granulosus serine threonine protein kinase nrc 0.043 0.1074 0.153
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0205 0.0328 0.2551
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Echinococcus multilocularis Immunoglobulin 0.0162 0.0183 0.0261
Echinococcus granulosus tyrosine protein kinase Src42A 0.0393 0.0953 0.1357
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0156 0.0165 0.0215
Entamoeba histolytica protein kinase, putative 0.0131 0.0081 0.0187
Echinococcus granulosus muscleblind protein 0.0153 0.0155 0.0221
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0442 0.1114 0.1588
Echinococcus multilocularis activin receptor type 0.0159 0.0173 0.0246
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0115 0.0091
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0219 0.0373 0.0532
Brugia malayi Protein kinase domain containing protein 0.0302 0.0649 0.0627
Trichomonas vaginalis AGC family protein kinase 0.0381 0.0912 0.3778
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0365 0.086 0.1225
Giardia lamblia Kinase, NEK 0.0417 0.1031 0.4165
Echinococcus granulosus tyrosine protein kinase 0.0373 0.0885 0.1261
Echinococcus granulosus epidermal growth factor receptor 0.1139 0.3431 0.4888
Schistosoma mansoni serine/threonine protein kinase 0.1281 0.3903 0.5552
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0846 0.2457 0.3501
Echinococcus multilocularis dual specificity 0.0198 0.0302 0.0431
Echinococcus granulosus protein kinase 0.0214 0.0358 0.0511
Entamoeba histolytica casein kinase, putative 0.0296 0.063 0.2541
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0219 0.0373 0.035
Schistosoma mansoni protein kinase C mu 0.0124 0.0056 0.0059
Trypanosoma cruzi rac serine-threonine kinase, putative 0.043 0.1074 0.4351
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0249 0.0473 0.0674
Toxoplasma gondii histone kinase SNF1, putative 0.0187 0.0268 0.0941
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0359 0.0838 0.1194
Schistosoma mansoni protein kinase C mu 0.0541 0.1444 0.2041
Brugia malayi RhoGEF domain containing protein 0.0124 0.0056 0.0033
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0381 0.0912 0.3752
Toxoplasma gondii AGC kinase 0.08 0.2305 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0219 0.0373 0.0512
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0492 0.1282 0.1826
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0395 0.0958 0.3974
Loa Loa (eye worm) hypothetical protein 0.0162 0.0183 0.016
Schistosoma mansoni unc-13 (munc13) 0.0128 0.007 0.0079
Brugia malayi Protein kinase domain containing protein 0.0159 0.0174 0.015
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1281 0.3903 0.3889
Loa Loa (eye worm) hypothetical protein 0.0156 0.0165 0.0142
Echinococcus multilocularis cyclin dependent kinase 1 0.0359 0.0838 0.1194
Loa Loa (eye worm) hypothetical protein 0.0398 0.0969 0.0948
Echinococcus multilocularis protein kinase c iota type 0.0843 0.2448 0.3488
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.0302 0.1136
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Echinococcus granulosus dual specificity 0.037 0.0876 0.1248
Echinococcus granulosus Glutaredoxin protein 5 0.0358 0.0836 0.1192
Giardia lamblia Kinase, CMGC DYRK 0.0198 0.0302 0.097
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0817 0.2362 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0817 0.2362 0.333
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0702 0.1981 0.2822
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0243 0.0454 0.1633
Trypanosoma cruzi casein kinase, putative 0.0243 0.0454 0.1633
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Brugia malayi Protein kinase domain containing protein 0.0139 0.0107 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0679 0.1903 0.1884
Loa Loa (eye worm) hypothetical protein 0.0186 0.0263 0.024
Brugia malayi Ras association domain family 1 isoform A 0.0124 0.0056 0.0033
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0273 0.0554 0.0532
Trichomonas vaginalis STE family protein kinase 0.0249 0.0473 0.1903
Trypanosoma brucei cdc2-related kinase 3 0.0359 0.0838 0.3308
Schistosoma mansoni protein kinase 0.0243 0.0454 0.0627
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0153 0.0154 0.022
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0187 0.0268 0.0819
Echinococcus multilocularis N chimaerin 0.0195 0.0294 0.0419
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0566 0.1528 0.1508
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0107 0.0341
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Onchocerca volvulus 0.0219 0.0373 0.0481
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0219 0.0373 0.0512
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0234 0.0423 0.04
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0227 0.0399 0.0548
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0178 0.0237 0.0804
Echinococcus multilocularis serine threonine protein kinase 0.0579 0.157 0.2237
Echinococcus granulosus hypothetical protein 0.0144 0.0123 0.0175
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus granulosus serine/threonine protein kinase 0.0449 0.1138 0.1621
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Loa Loa (eye worm) TK/EPH protein kinase 0.036 0.0843 0.0822
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0178 0.0237 0.0214
Echinococcus multilocularis aurora kinase A 0.0381 0.0912 0.13
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0118 0.0037 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0633 0.175 0.2493
Entamoeba histolytica cell division protein kinase 2, putative 0.0359 0.0838 0.3433
Schistosoma mansoni tyrosine kinase 0.0633 0.175 0.2477
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Echinococcus granulosus c-Jun N-terminal kinases 0.0846 0.2457 0.3501
Echinococcus granulosus serine:threonine protein kinase 0.0302 0.0649 0.0925
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0249 0.0473 0.0674
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0102 0.0146
Entamoeba histolytica protein kinase, putative 0.0819 0.2369 1
Schistosoma mansoni tyrosine kinase 0.0447 0.113 0.1592
Giardia lamblia Kinase, PLK 0.0817 0.2362 1
Schistosoma mansoni protein kinase 0.0381 0.0912 0.1281
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.1981 0.2807
Echinococcus granulosus dual specificity 0.0198 0.0302 0.0431
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0397 0.0964 0.0942
Giardia lamblia Kinase, CMGC MAPK 0.0241 0.0448 0.1607
Echinococcus granulosus titin 0.0141 0.0115 0.0163
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0205 0.0328 0.1208
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0205 0.0328 0.1083
Loa Loa (eye worm) hypothetical protein 0.047 0.1207 0.1186
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0178 0.0237 0.0338
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0262 0.0515 0.0493
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0102 0.0125
Loa Loa (eye worm) TK protein kinase 0.0254 0.0489 0.0467
Schistosoma mansoni biogenic amine (5HT) receptor 0.0139 0.0106 0.0131
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0466 0.1195 0.1174
Echinococcus granulosus tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Brugia malayi Cation transporter family protein 0.0219 0.0373 0.035
Loa Loa (eye worm) protein kinase domain-containing protein 0.0286 0.0596 0.0574
Loa Loa (eye worm) ACC-1 protein 0.0219 0.0373 0.035
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0195 0.0294 0.0271
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0215 0.036 0.0337
Plasmodium falciparum calcium-dependent protein kinase 4 0.0178 0.0237 0.1643
Trypanosoma cruzi cdc2-related kinase 3 0.0359 0.0838 0.3318
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0575 0.1556 0.2217
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0205 0.0328 0.0305
Echinococcus granulosus unc 13 munc13 0.0128 0.007 0.01
Echinococcus granulosus mitogen activated protein kinase 11 0.0494 0.1287 0.1833
Echinococcus multilocularis unc 13 (munc13) 0.0128 0.007 0.01
Entamoeba histolytica protein kinase, putative 0.0381 0.0912 0.3752
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0381 0.0912 0.3752
Leishmania major casein kinase II, putative 0.0296 0.063 0.2406
Brugia malayi Hr1 repeat family protein 0.0596 0.1628 0.1608
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0102 0.0125
Echinococcus multilocularis Rac GTPase activating protein 1 0.0124 0.0056 0.008
Entamoeba histolytica protein kinase domain containing protein 0.0381 0.0912 0.3752
Echinococcus multilocularis c src tyrosine kinase 0.0227 0.0399 0.0568
Echinococcus granulosus dual specificity 0.0198 0.0302 0.0431
Trichomonas vaginalis STE family protein kinase 0.0249 0.0473 0.1903
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0219 0.0373 0.035
Echinococcus granulosus twitchin 0.0279 0.0573 0.0817
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0133 0.0088 0.0126
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1636 0.5084 0.7244
Onchocerca volvulus 0.1045 0.3121 0.4417
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0393 0.0953 0.1357
Loa Loa (eye worm) hypothetical protein 0.0278 0.057 0.0547
Echinococcus multilocularis casein kinase I alpha 0.0243 0.0454 0.0646
Trypanosoma brucei casein kinase I, isoform 2 0.0243 0.0454 0.1628
Loa Loa (eye worm) hypothetical protein 0.0116 0.0031 0.0007
Echinococcus multilocularis dual specificity 0.0198 0.0302 0.0431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0102 0.0146
Schistosoma mansoni nephrin 0.0232 0.0416 0.0572
Echinococcus granulosus glycine receptor subunit beta 0.0219 0.0373 0.0532
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Loa Loa (eye worm) hypothetical protein 0.0139 0.0109 0.0085
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0185 0.0261 0.0238
Loa Loa (eye worm) hypothetical protein 0.0153 0.0155 0.0132
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0219 0.0373 0.035
Loa Loa (eye worm) hypothetical protein 0.0174 0.0223 0.0199
Loa Loa (eye worm) hypothetical protein 0.0568 0.1535 0.1515
Brugia malayi intracellular kinase 0.0343 0.0786 0.0765
Echinococcus granulosus casein kinase ii subunit alpha 0.0296 0.063 0.0898
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0632 0.0881
Onchocerca volvulus 0.0159 0.0174 0.0195
Schistosoma mansoni protein kinase 0.0575 0.1556 0.22
Loa Loa (eye worm) TK/ROR protein kinase 0.0133 0.0088 0.0065
Echinococcus granulosus casein kinase I alpha 0.0243 0.0454 0.0646
Trypanosoma brucei rac serine-threonine kinase, putative 0.0819 0.2369 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Onchocerca volvulus 0.0128 0.007 0.0047
Entamoeba histolytica protein kinase, putative 0.0234 0.0423 0.1652
Giardia lamblia Kinase, CMGC CLK 0.0215 0.036 0.1224
Trypanosoma brucei protein kinase, putative 0.0343 0.0786 0.3082
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0423 0.0582
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0476 0.1226 0.1747
Plasmodium vivax glycogen synthase kinase 3, putative 0.0343 0.0786 0.7245
Entamoeba histolytica protein kinase , putative 0.0381 0.0912 0.3752
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus multilocularis hypothetical protein 0.0174 0.0223 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Giardia lamblia Aurora kinase 0.0381 0.0912 0.3644
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0205 0.0328 0.108
Schistosoma mansoni serine/threonine protein kinase 0.0633 0.175 0.2478
Brugia malayi Immunoglobulin I-set domain containing protein 0.0186 0.0263 0.024
Echinococcus multilocularis roundabout 2 0.0114 0.0024 0.0034
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0178 0.0237 0.0804
Entamoeba histolytica protein kinase, putative 0.08 0.2305 0.9726
Trypanosoma cruzi casein kinase, putative 0.0243 0.0454 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.0596 0.1628 0.2303
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0449 0.1138 0.4632
Loa Loa (eye worm) AUR protein kinase 0.0381 0.0912 0.0891
Echinococcus granulosus Vam6:Vps39 protein 0.0156 0.0165 0.0235
Onchocerca volvulus 0.0139 0.0107 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0107 0.0341
Trypanosoma cruzi cdc2-related kinase 1 0.0359 0.0838 0.3318
Brugia malayi Immunoglobulin I-set domain containing protein 0.1338 0.4095 0.4081
Schistosoma mansoni tyrosine kinase 0.0393 0.0953 0.1339
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0493 0.1284 0.1263
Onchocerca volvulus 0.0243 0.0454 0.0596
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0219 0.0373 0.035
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0219 0.0373 0.0532
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0178 0.0237 0.0338
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0393 0.0953 0.1357
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0241 0.0448 0.1607
Brugia malayi Cation transporter family protein 0.0219 0.0373 0.035
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0156 0.0165 0.0215
Echinococcus multilocularis mitogen activated protein kinase 3 0.0241 0.0448 0.0638
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.0596 0.083
Echinococcus granulosus biogenic amine 5HT receptor 0.0139 0.0106 0.0151
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.051 0.1341 0.191
Giardia lamblia Kinase, CMGC CK2 0.0296 0.063 0.2406
Loa Loa (eye worm) hypothetical protein 0.0116 0.0031 0.0007
Echinococcus multilocularis nAChR subunit 0.0219 0.0373 0.0532
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.08 0.2305 0.2287
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Onchocerca volvulus Putative nachr subunit 0.0219 0.0373 0.0481
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0205 0.0328 0.1083
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0155 0.0221
Echinococcus multilocularis nervana 2 0.0358 0.0836 0.1192
Schistosoma mansoni nck2/grb4 0.0139 0.0109 0.0134
Schistosoma mansoni vav2 0.0214 0.0358 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0384 0.0922 0.3821
Brugia malayi Protein kinase domain containing protein 0.0633 0.175 0.1731
Echinococcus granulosus serine:threonine protein kinase 3 0.0821 0.2374 0.3383
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.036 0.1421
Trichomonas vaginalis AGC family protein kinase 0.0234 0.0423 0.1687
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.043 0.1074 0.153
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0219 0.0373 0.0532
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0114 0.0024 0.0034
Brugia malayi Protein kinase domain containing protein 0.0227 0.0402 0.0379
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0372 0.0883 0.3514
Entamoeba histolytica protein kinase, putative 0.0381 0.0912 0.3752
Plasmodium vivax tyrosine kinase-like protein, putative 0.0129 0.0073 0.0397
Echinococcus granulosus nAChR subunit 0.0219 0.0373 0.0532
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0393 0.0953 0.1357
Echinococcus multilocularis roundabout 2 0.0276 0.0562 0.08
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0141 0.0115 0.0091
Schistosoma mansoni protein kinase 0.0249 0.0473 0.0654
Entamoeba histolytica protein kinase domain containing protein 0.037 0.0876 0.3597
Loa Loa (eye worm) hypothetical protein 0.0465 0.119 0.1169
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0215 0.036 0.1351
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0381 0.0912 0.13
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0393 0.0953 0.1357
Echinococcus granulosus Immunoglobulin 0.0162 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0325 0.0727 0.1036
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0156 0.0165 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0343 0.0786 0.3241
Onchocerca volvulus 0.0346 0.0796 0.1087
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0417 0.1031 0.4334
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0178 0.0237 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0846 0.2457 0.3487
Schistosoma mansoni nephrin 0.0114 0.0024 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.1981 0.2807
Giardia lamblia Kinase, CMGC CDK 0.0359 0.0838 0.3318
Trypanosoma brucei SNF1-related protein kinases, putative 0.0187 0.0268 0.0817
Loa Loa (eye worm) hypothetical protein 0.0489 0.1271 0.125
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Leishmania major protein kinase, putative 0.0215 0.036 0.1224
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2218 0.7018 0.7011
Schistosoma mansoni protein kinase 0.0214 0.0358 0.049
Echinococcus granulosus cyclin dependent kinase 5 0.0359 0.0838 0.1194
Echinococcus granulosus ephrin type A receptor 4 A 0.0302 0.0648 0.0923
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0494 0.1287 0.5286
Loa Loa (eye worm) hypothetical protein 0.0139 0.0106 0.0083
Brugia malayi casein kinase I 0.0243 0.0454 0.0431
Echinococcus multilocularis serotonin receptor 0.0139 0.0106 0.0151
Schistosoma mansoni tyrosine kinase 0.1139 0.3431 0.4878
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0187 0.0268 0.0817
Schistosoma mansoni serine/threonine protein kinase 0.051 0.1341 0.1893
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0241 0.0448 0.1607
Brugia malayi Protein kinase domain containing protein 0.0234 0.0423 0.04
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0187 0.0268 0.0819
Trypanosoma cruzi Protein kinase B 0.0449 0.1138 0.4632
Echinococcus granulosus dual specificity protein kinase clk2 0.0215 0.036 0.0513
Schistosoma mansoni tyrosine kinase 0.0682 0.1911 0.2708
Trichomonas vaginalis AGC family protein kinase 0.0381 0.0912 0.3778
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0134 0.0091 0.013
Plasmodium vivax casein kinase 1, putative 0.0243 0.0454 0.4052
Brugia malayi P38 map kinase family protein 2 0.0494 0.1287 0.1266
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0178 0.0237 0.0338
Echinococcus granulosus glycine receptor subunit beta 0.0219 0.0373 0.0532
Trichomonas vaginalis AGC family protein kinase 0.0417 0.1031 0.4285
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0476 0.1226 0.1747
Leishmania major protein kinase A catalytic subunit 0.0205 0.0328 0.1083
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0633 0.175 0.2493
Loa Loa (eye worm) AGC/PKA protein kinase 0.0205 0.0328 0.0305
Echinococcus granulosus biogenic amine 5HT receptor 0.0418 0.1034 0.1473
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.046 0.0635
Schistosoma mansoni cell adhesion molecule 0.0114 0.0024 0.0013
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0621 0.1709 0.2435
Toxoplasma gondii casein kinase I 0.0243 0.0454 0.1766
Schistosoma mansoni serine/threonine kinase 0.0442 0.1114 0.157
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Schistosoma mansoni growth factor receptor-bound protein 0.0139 0.0109 0.0134
Echinococcus multilocularis glycine receptor subunit beta 0.0219 0.0373 0.0532
Schistosoma mansoni tyrosine kinase 0.0177 0.0235 0.0314
Echinococcus granulosus tyrosine protein kinase Src42A 0.0238 0.0437 0.0623
Onchocerca volvulus 0.0343 0.0786 0.1073
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0131 0.0081 0.0057
Loa Loa (eye worm) AGC/AKT protein kinase 0.0819 0.2369 0.2351
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0273 0.0554 0.079
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Loa Loa (eye worm) hypothetical protein 0.0404 0.0988 0.0967
Echinococcus multilocularis mitogen activated protein kinase 0.0241 0.0448 0.0638
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0124 0.0056 0.0033
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0679 0.1903 0.2712
Schistosoma mansoni tyrosine kinase 0.0682 0.1911 0.2708
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0144 0.0124 0.01
Brugia malayi serine/threonine-protein kinase 6 0.0381 0.0912 0.0891
Onchocerca volvulus 0.0172 0.0216 0.0257
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0219 0.0373 0.0532
Schistosoma mansoni serine/threonine protein kinase 0.0817 0.2362 0.3352
Giardia lamblia Kinase, NEK 0.0417 0.1031 0.4165
Loa Loa (eye worm) hypothetical protein 0.0118 0.0037 0.0014
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0195 0.0294 0.0419
Giardia lamblia Kinase, CMGC GSK 0.0343 0.0786 0.3092
Loa Loa (eye worm) hypothetical protein 0.0133 0.0087 0.0063
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0418 0.1034 0.1473
Schistosoma mansoni cell adhesion molecule 0.0114 0.0024 0.0013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0159 0.0173 0.0402
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0359 0.0838 0.0816
Echinococcus multilocularis dual specificity 0.037 0.0876 0.1248
Schistosoma mansoni vam6/vps39 related 0.0156 0.0165 0.0215
Loa Loa (eye worm) hypothetical protein 0.0299 0.0639 0.0617
Loa Loa (eye worm) hypothetical protein 0.0187 0.0268 0.0245
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0633 0.175 0.2493
Echinococcus granulosus glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0219 0.0373 0.035
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0297 0.0632 0.0609
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0219 0.0373 0.0512
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0156 0.0165 0.0369
Echinococcus multilocularis serine:threonine protein kinase 0.0302 0.0649 0.0925
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0156 0.0165 0.0369
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Loa Loa (eye worm) ACC-1 protein 0.0219 0.0373 0.035
Schistosoma mansoni protein kinase 0.0679 0.1903 0.2697
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0243 0.0454 0.0431
Loa Loa (eye worm) RasGEF domain-containing protein 0.0124 0.0056 0.0033
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2218 0.7018 1
Brugia malayi Fibronectin type III domain containing protein 0.0186 0.0263 0.024
Plasmodium falciparum serine/threonine protein kinase KIN 0.0187 0.0268 0.195
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0234 0.0423 0.0602
Echinococcus granulosus Rac GTPase activating protein 1 0.0124 0.0056 0.008
Loa Loa (eye worm) casein kinase 0.0215 0.0359 0.0336
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Trichomonas vaginalis AGC family protein kinase 0.0234 0.0423 0.1687
Echinococcus multilocularis serine:threonine protein kinase 38 0.0442 0.1114 0.1588
Trypanosoma cruzi aurora B kinase, putative 0.0381 0.0912 0.3644
Entamoeba histolytica protein kinase, putative 0.0143 0.0121 0.0356
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0215 0.036 0.1224
Schistosoma mansoni growth factor receptor-bound protein 0.0139 0.0109 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0328 0.0447
Onchocerca volvulus 0.0159 0.0174 0.0195
Echinococcus multilocularis 0.0214 0.0358 0.0511
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0442 0.1114 0.1588
Entamoeba histolytica protein kinase, putative 0.0196 0.0296 0.1107
Schistosoma mansoni protein kinase 0.0176 0.0232 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0402 0.0552
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0249 0.0473 0.0674
Entamoeba histolytica protein kinase, putative 0.0249 0.0473 0.1868
Onchocerca volvulus 0.0219 0.0373 0.0481
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0219 0.0373 0.0532
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0268 0.0819
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0268 0.0819
Brugia malayi MAP kinase sur-1 0.0241 0.0448 0.0425
Echinococcus granulosus mitogen activated protein kinase 0.0241 0.0448 0.0638
Brugia malayi Variant SH3 domain containing protein 0.0195 0.0294 0.0271
Giardia lamblia Kinase, CMGC CDK 0.0359 0.0838 0.3318
Loa Loa (eye worm) hypothetical protein 0.0139 0.0106 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0115 0.0143
Echinococcus multilocularis insulin receptor 0.0908 0.2664 0.3796
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0107 0.0132
Echinococcus multilocularis tyrosine protein kinase Srms 0.0325 0.0727 0.1036
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.036 0.0493
Onchocerca volvulus 0.0139 0.0107 0.01
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.051 0.1341 0.132
Schistosoma mansoni hypothetical protein 0.0174 0.0223 0.0297
Trichomonas vaginalis STE family protein kinase 0.0417 0.1031 0.4285
Schistosoma mansoni protein kinase 0.0371 0.0878 0.1233
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.057 0.1539 0.1519
Brugia malayi putative serine/threonine kinase SADA gamma 0.0187 0.0268 0.0245
Plasmodium falciparum protein kinase 5 0.0359 0.0838 0.7646
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0219 0.0373 0.035
Brugia malayi Fes/CIP4 homology domain containing protein 0.0153 0.0155 0.0131
Brugia malayi map kinase activated protein kinase protein 2 0.1281 0.3903 0.3889
Leishmania major protein kinase, putative 0.0159 0.0173 0.0402
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Schistosoma mansoni serine/threonine protein kinase 0.1049 0.3135 0.4454
Entamoeba histolytica diacylglycerol kinase, putative 0.0124 0.0056 0.0081
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0178 0.0237 0.0214
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Echinococcus granulosus casein kinase I alpha 0.0243 0.0454 0.0646
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0219 0.0373 0.0512
Loa Loa (eye worm) hypothetical protein 0.0549 0.1472 0.1452
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0195 0.0294 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0838 0.1175
Echinococcus multilocularis casein kinase I gamma 0.0286 0.0596 0.0849
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0187 0.0268 0.0819
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0219 0.0373 0.0532
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0187 0.0268 0.0382
Entamoeba histolytica protein kinase, putative 0.0153 0.0154 0.0501
Giardia lamblia Kinase, NEK 0.0417 0.1031 0.4165
Echinococcus multilocularis neuroglian 0.0208 0.0336 0.0479
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0228 0.0402 0.0573
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0214 0.0358 0.0335
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0205 0.0328 0.0467
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0215 0.036 0.1224
Echinococcus granulosus contactin 0.0114 0.0024 0.0034
Echinococcus granulosus c src tyrosine kinase 0.0227 0.0399 0.0568
Brugia malayi Protein kinase domain containing protein 0.0492 0.1282 0.1261
Plasmodium falciparum calcium-dependent protein kinase 5 0.0178 0.0237 0.1643
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0273 0.0554 0.0532
Trypanosoma brucei aurora B kinase 0.0381 0.0912 0.3632
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0353 0.0819 0.0797
Leishmania major protein kinase, putative 0.0178 0.0237 0.0685
Echinococcus granulosus nAChR subunit 0.0118 0.0037 0.0053
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0198 0.0302 0.097
Echinococcus granulosus casein kinase I delta 0.0243 0.0454 0.0646
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Echinococcus granulosus nervana 2 0.0358 0.0836 0.1192
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0343 0.0786 0.0765
Trypanosoma cruzi casein kinase, putative 0.0243 0.0454 0.1633
Echinococcus multilocularis protein kinase c eta type 0.0124 0.0056 0.008
Schistosoma mansoni nAChR subunit 0.0219 0.0373 0.0512
Brugia malayi diacylglycerol kinase 0.0124 0.0056 0.0033
Trichomonas vaginalis CK1 family protein kinase 0.0243 0.0454 0.182
Echinococcus multilocularis CDC7 cell division cycle 7 0.0139 0.0107 0.0153
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0448 0.1794
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0198 0.0302 0.0279
Plasmodium vivax serine/threonine protein kinase, putative 0.0131 0.0081 0.0477
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0134 0.0091 0.013
Schistosoma mansoni adapter molecule crk 0.0139 0.0109 0.0134
Loa Loa (eye worm) hypothetical protein 0.0252 0.0482 0.046
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0393 0.0953 0.1357
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0492 0.1282 0.1826
Trichomonas vaginalis STE family protein kinase 0.0176 0.0232 0.0872
Plasmodium falciparum protein serine/threonine kinase-1 0.0215 0.036 0.2873
Trichomonas vaginalis STE family protein kinase 0.0244 0.0458 0.1838
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0198 0.0302 0.1093
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0206 0.033 0.047
Giardia lamblia Kinase, AGC AKT 0.0353 0.0819 0.3234
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.057 0.1539 0.2177
Echinococcus granulosus tyrosine protein kinase shark 0.0159 0.0174 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.046 0.0635
Brugia malayi hypothetical protein 0.0156 0.0165 0.0142
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0129 0.0073 0.0073
Echinococcus multilocularis death associated protein kinase 1 0.0899 0.2633 0.3752
Schistosoma mansoni tyrosine kinase 0.0227 0.0399 0.0548
Brugia malayi Protein kinase domain containing protein 0.0442 0.1114 0.1093
Brugia malayi Protein kinase domain containing protein 0.0159 0.0174 0.015
Trypanosoma cruzi casein kinase, putative 0.0243 0.0454 0.1633
Plasmodium falciparum serine/threonine protein kinase, putative 0.0381 0.0912 0.8388
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0343 0.0786 0.1102
Schistosoma mansoni biogenic amine (5HT) receptor 0.0418 0.1034 0.1455
Plasmodium falciparum NIMA related kinase 1 0.0417 0.1031 0.9575
Leishmania major protein kinase, putative 0.0381 0.0912 0.3644
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.051 0.1341 0.132
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0494 0.1287 0.5286
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0153 0.0154 0.022
Loa Loa (eye worm) hypothetical protein 0.0178 0.0236 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.046 0.0635
Schistosoma mansoni cell adhesion molecule 0.023 0.0409 0.0563
Brugia malayi Protein kinase domain containing protein 0.0819 0.2369 0.2351
Entamoeba histolytica protein kinase, putative 0.0182 0.0251 0.0917
Schistosoma mansoni serine/threonine kinase 0.0245 0.046 0.0635
Echinococcus multilocularis casein kinase I alpha 0.0243 0.0454 0.0646
Echinococcus granulosus tyrosine kinase 0.0325 0.0727 0.1036
Loa Loa (eye worm) hypothetical protein 0.0285 0.0595 0.0572
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0541 0.1444 0.1424
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0215 0.036 0.1224
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0102 0.0125
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0302 0.1173
Schistosoma mansoni tyrosine kinase 0.0682 0.1911 0.2708
Echinococcus multilocularis tyrosine protein kinase shark 0.0159 0.0174 0.0247
Entamoeba histolytica protein kinase, putative 0.0442 0.1114 0.4618
Echinococcus multilocularis Immunoglobulin 0.0162 0.0183 0.0261
Brugia malayi Casein kinase II, alpha chain 0.0296 0.063 0.0608
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0156 0.0165 0.0235
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0241 0.0448 0.0425
Trichomonas vaginalis AGC family protein kinase 0.0442 0.1114 0.4641
Trypanosoma cruzi casein kinase II, putative 0.0296 0.063 0.2406
Brugia malayi Protein kinase domain containing protein 0.0908 0.2664 0.2647
Onchocerca volvulus 0.0978 0.2897 0.4097
Loa Loa (eye worm) hypothetical protein 0.0156 0.0165 0.0142
Loa Loa (eye worm) hypothetical protein 0.0588 0.1601 0.1581
Leishmania major protein kinase, putative 0.0215 0.036 0.1224
Plasmodium vivax unspecified product 0.0296 0.063 0.5744
Plasmodium falciparum calcium-dependent protein kinase 1 0.0178 0.0237 0.1643
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0187 0.0268 0.227
Trichomonas vaginalis AGC family protein kinase 0.0819 0.2369 1
Giardia lamblia Kinase, AGC PKA 0.0205 0.0328 0.1083
Entamoeba histolytica casein kinase 1, putative 0.0243 0.0454 0.1785
Leishmania major protein kinase, putative 0.0244 0.0458 0.1652
Trichomonas vaginalis CMGC family protein kinase 0.0359 0.0838 0.3461
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0575 0.1556 0.2217
Echinococcus granulosus glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Entamoeba histolytica casein kinase, putative 0.0243 0.0454 0.1785
Giardia lamblia Kinase, AGC PKA 0.043 0.1074 0.4351
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0381 0.0912 0.3752
Echinococcus granulosus rho-associated protein kinase 1 0.1049 0.3135 0.4466
Brugia malayi SRC-1 0.0393 0.0953 0.0931
Schistosoma mansoni titin 0.0141 0.0115 0.0143
Loa Loa (eye worm) hypothetical protein 0.0465 0.119 0.1169
Echinococcus granulosus casein kinase I delta 0.0243 0.0454 0.0646
Loa Loa (eye worm) hypothetical protein 0.0219 0.0373 0.035
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0514 0.1353 0.1928
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0118 0.0037 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0234 0.0423 0.1687
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0102 0.0079
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.051 0.1341 0.191
Giardia lamblia Kinase, STE STE20 0.0244 0.0458 0.1652
Loa Loa (eye worm) hypothetical protein 0.0465 0.119 0.1169
Echinococcus multilocularis serine:threonine protein kinase 3 0.0821 0.2374 0.3383
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0124 0.0156
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0397 0.0964 0.0942
Brugia malayi Doublecortin family protein 0.0212 0.0349 0.0326
Entamoeba histolytica protein kinase domain containing protein 0.0296 0.063 0.2541
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0118 0.0037 0.0032
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0234 0.0423 0.04
Loa Loa (eye worm) hypothetical protein 0.0303 0.0652 0.063
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus granulosus defective proboscis extension response 0.0162 0.0183 0.0261
Echinococcus granulosus tyrosine kinase 0.0159 0.0174 0.0247
Loa Loa (eye worm) LGC-31 protein 0.0219 0.0373 0.035
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0343 0.0786 0.3092
Brugia malayi STE20-like kinase MST 0.0821 0.2374 0.2356
Brugia malayi phosphoinositide-dependent protein kinase I 0.0234 0.0423 0.04
Echinococcus granulosus protein kinase shaggy 0.0343 0.0786 0.112
Plasmodium vivax serine/threonine kinase-1, putative 0.0215 0.036 0.3156
Echinococcus granulosus tyrosine protein kinase ABL1 0.0159 0.0174 0.0247
Trichomonas vaginalis CK1 family protein kinase 0.0243 0.0454 0.182
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0219 0.0373 0.035
Schistosoma mansoni rac gtpase activating protein 0.0124 0.0056 0.0059
Onchocerca volvulus Tyrosine kinase homolog 0.1179 0.3564 0.5052
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0156 0.0165 0.0235
Brugia malayi Variant SH3 domain containing protein 0.0139 0.0109 0.0085
Echinococcus granulosus mitogen activated protein kinase 14 0.0494 0.1287 0.1833
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.063 0.2573
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0219 0.0373 0.035
Brugia malayi serine/threonine protein kinase 6 0.0381 0.0912 0.0891
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0178 0.0237 0.1975
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0932 0.2743 0.3909
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Entamoeba histolytica PH domain containing protein kinase, putative 0.0225 0.0392 0.1521
Entamoeba histolytica protein kinase, putative 0.0176 0.0232 0.0833
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Brugia malayi serine/threonine-protein kinase plk-2 0.0817 0.2362 0.2344
Schistosoma mansoni ste20-related kinase 0.0648 0.1799 0.2547
Schistosoma mansoni rap gtpase-activating protein 0.0156 0.0165 0.0215
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0296 0.063 0.5744
Echinococcus multilocularis calcium activated potassium channel 0.0245 0.046 0.0655
Schistosoma mansoni diacylglycerol kinase theta 0.0124 0.0056 0.0059
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0332 0.075 0.1069
Plasmodium falciparum calcium-dependent protein kinase 2 0.0178 0.0237 0.1643
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0343 0.0786 0.0765
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Echinococcus granulosus casein kinase i 0.0243 0.0454 0.0646
Onchocerca volvulus 0.0159 0.0174 0.0195
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0393 0.0953 0.1357
Echinococcus granulosus roundabout 2 0.0276 0.0562 0.08
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0219 0.0373 0.0532
Echinococcus granulosus cyclin dependent kinase 1 0.0359 0.0838 0.1194
Trichomonas vaginalis CAMK family protein kinase 0.0817 0.2362 0.9969
Echinococcus multilocularis tyrosine kinase 0.0159 0.0174 0.0247
Plasmodium falciparum casein kinase 2, alpha subunit 0.0296 0.063 0.5568
Echinococcus multilocularis cyclin dependent kinase 1 0.0359 0.0838 0.1194
Entamoeba histolytica serine/threonine protein kinase, putative 0.0187 0.0268 0.0988
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0393 0.0953 0.1357
Brugia malayi Protein kinase domain containing protein 0.04 0.0977 0.0955
Echinococcus multilocularis rho associated protein kinase 0.1049 0.3135 0.4466
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0219 0.0373 0.035
Brugia malayi Tyrosine-protein kinase abl-1 0.0227 0.0399 0.0376
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0114 0.0024 0.0034
Brugia malayi Protein kinase c protein 2 0.0332 0.0749 0.0727
Loa Loa (eye worm) TK/FER protein kinase 0.0159 0.0174 0.015
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0219 0.0373 0.0532
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0153 0.0154 0.022
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0817 0.2362 0.3366
Echinococcus multilocularis mitogen activated protein kinase 14 0.0494 0.1287 0.1833
Trypanosoma cruzi p21-activated kinase 3, putative 0.0144 0.0124 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0476 0.1226 0.173
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0241 0.0448 0.1607
Echinococcus granulosus Diacylglycerol kinase theta 0.0124 0.0056 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0384 0.0922 0.3821
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0144 0.0124 0.0188
Echinococcus granulosus roundabout 2 0.0114 0.0024 0.0034
Echinococcus multilocularis rac serine:threonine kinase 0.0449 0.1138 0.1621
Schistosoma mansoni kinase 0.0765 0.219 0.3106
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0912 0.1281
Echinococcus granulosus serine:threonine kinase SAD 1 0.0187 0.0268 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.1353 0.1911
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0821 0.2374 0.2356
Schistosoma mansoni serine/threonine protein kinase 0.0723 0.2051 0.2907
Trypanosoma cruzi cdc2-related kinase 3 0.0359 0.0838 0.3318
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0219 0.0373 0.0532
Loa Loa (eye worm) hypothetical protein 0.0163 0.0186 0.0162
Brugia malayi Serine/threonine-protein kinase SULU 0.0297 0.0632 0.0609
Entamoeba histolytica protein kinase, putative 0.0819 0.2369 1
Loa Loa (eye worm) TK protein kinase 0.0679 0.1903 0.1884
Loa Loa (eye worm) TK protein kinase 0.0373 0.0885 0.0863
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0234 0.0423 0.0602
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.043 0.1074 0.153
Loa Loa (eye worm) hypothetical protein 0.0124 0.0056 0.0033
Loa Loa (eye worm) hypothetical protein 0.0278 0.057 0.0547
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0343 0.0786 0.112
Trichomonas vaginalis CAMK family protein kinase 0.0187 0.0268 0.1027
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0219 0.0373 0.0532
Trichomonas vaginalis AGC family protein kinase 0.0381 0.0912 0.3778
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0249 0.0473 0.0674
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0343 0.0786 0.3246
Leishmania major protein kinase A catalytic subunit isoform 1 0.0205 0.0328 0.1083
Loa Loa (eye worm) hypothetical protein 0.0252 0.0482 0.046
Entamoeba histolytica serine/threonine protein kinase, putative 0.0817 0.2362 0.9969
Entamoeba histolytica hypothetical protein 0.037 0.0876 0.3597

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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