Detailed information for compound 1306677

Basic information

Technical information
  • TDR Targets ID: 1306677
  • Name: methyl 4-[[4-dimethylamino-6-(propan-2-ylamin o)-1,3,5-triazin-2-yl]oxy]benzoate
  • MW: 331.37 | Formula: C16H21N5O3
  • H donors: 1 H acceptors: 4 LogP: 3.26 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)Oc1nc(NC(C)C)nc(n1)N(C)C
  • InChi: 1S/C16H21N5O3/c1-10(2)17-14-18-15(21(3)4)20-16(19-14)24-12-8-6-11(7-9-12)13(22)23-5/h6-10H,1-5H3,(H,17,18,19,20)
  • InChiKey: PRRWMENYGHHXAG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 4-[[4-dimethylamino-6-(isopropylamino)-1,3,5-triazin-2-yl]oxy]benzoate
  • 4-[[4-dimethylamino-6-(isopropylamino)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl ester
  • 4-[[4-dimethylamino-6-(isopropylamino)-s-triazin-2-yl]oxy]benzoic acid methyl ester
  • SMR000014056
  • ST062314
  • ZINC00804331
  • 4-(4-Dimethylamino-6-isopropylamino-[1,3,5]triazin-2-yloxy)-benzoic acid methyl ester
  • 4-(4-Dimethylamino-6-isopropylamino-[1,3,5]triazin-2-yloxy)-benzoic acid methyl
  • BAS 06969303
  • MLS000034910

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.029 0.1242 0.1864
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0064 0.0416
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Echinococcus granulosus cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0015 0.0008
Echinococcus multilocularis apoptotic protease activating factor 1 0.0154 0.0604 0.0901
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0015 0.001
Echinococcus granulosus orexin receptor type 2 0.0029 0.0015 0.0007
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0046 0.006
Loa Loa (eye worm) hypothetical protein 0.0737 0.3344 0.5061
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0179 0.072 0.4673
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Brugia malayi CXXC zinc finger family protein 0.003 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0212 0.2772
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0499 0.2224 0.4926
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Brugia malayi Cathepsin L-like cysteine proteinase 0.0182 0.0735 0.1105
Brugia malayi GnHR receptor homolog 0.0029 0.0015 0.0012
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Onchocerca volvulus 0.0182 0.0735 0.1094
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0015 0.001
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0015 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.011 0.0151
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0154 0.0603 0.0559
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0015 0.001
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.023 0.0333
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0015 0.0007
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Loa Loa (eye worm) hypothetical protein 0.0139 0.0531 0.0791
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.011 0.0106
Leishmania major cysteine peptidase A (CPA) 0.0182 0.0735 0.2182
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Loa Loa (eye worm) inositol-1 0.0036 0.0047 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0051 0.0061
Onchocerca volvulus 0.004 0.0067 0.0079
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0015 0.0007
Trypanosoma brucei cysteine peptidase C (CPC) 0.0353 0.154 0.15
Loa Loa (eye worm) hypothetical protein 0.0373 0.163 0.246
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0097
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0139 0.0531 0.416
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0051 0.0131
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0018
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0064 0.0081
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0047 0.0056
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0064 0.018 0.0257
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.0957 0.1437
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0482 0.0717
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0015 0.0007
Echinococcus granulosus acylamino acid releasing enzyme 0.0139 0.0531 0.079
Trichomonas vaginalis chromobox protein, putative 0.0081 0.026 0.1691
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0015 0.0007
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0212 0.0454
Brugia malayi Pre-SET motif family protein 0.0032 0.0029 0.0033
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Giardia lamblia Encystation-specific protease 0.0071 0.0212 0.1
Loa Loa (eye worm) RNA binding protein 0.0128 0.0482 0.0717
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0047 0.0307
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Echinococcus multilocularis SAM and MBT domain containing protein 0.037 0.1617 0.2439
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0499 0.2224 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Brugia malayi hypothetical protein 0.036 0.1573 0.2376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Toxoplasma gondii cathepsin CPC1 0.0071 0.0212 0.0846
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Loa Loa (eye worm) norepinephrine transporter 0.0235 0.0984 0.1479
Trypanosoma cruzi cysteine protease, putative 0.0071 0.0212 0.0454
Giardia lamblia Cathepsin L-like protease 0.0071 0.0212 0.1
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0015 0.0007
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0015 0.0007
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0373 0.163 0.4864
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Mycobacterium tuberculosis Probable lipase LipD 0.0179 0.072 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0071 0.0212 0.1374
Plasmodium vivax hypothetical protein, conserved 0.0179 0.072 0.9785
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Brugia malayi fibroinase precursor 0.0071 0.0212 0.0311
Loa Loa (eye worm) hypothetical protein 0.0439 0.1944 0.2936
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Schistosoma mansoni alpha glucosidase 0.0036 0.0051 0.0046
Brugia malayi FAT domain containing protein 0.0028 0.001 0.0005
Trypanosoma cruzi oligopeptidase b 0.0215 0.089 0.1963
Loa Loa (eye worm) hypothetical protein 0.036 0.1573 0.2373
Echinococcus granulosus somatostatin receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) cathepsin B 0.0353 0.154 0.2323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0499 0.2224 0.336
Onchocerca volvulus Deterin homolog 0.0527 0.2356 0.3557
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.305 0.4614
Trypanosoma brucei hypothetical protein, conserved 0.0179 0.072 0.0676
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Schistosoma mansoni hypothetical protein 0.1194 0.549 0.5488
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0212 0.0311
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Onchocerca volvulus 0.003 0.0019 0.0007
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0067 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Brugia malayi Dopamine receptor protein 1 0.0029 0.0015 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Brugia malayi cathepsin L precursor 0.0071 0.0212 0.0311
Echinococcus multilocularis cathepsin b 0.0985 0.4507 0.6826
Echinococcus granulosus cathepsin L cysteine protease 0.0071 0.0212 0.0306
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0499 0.2224 0.2187
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Mycobacterium tuberculosis Probable lipase LipE 0.0179 0.072 0.1323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus granulosus SAM and MBT domain containing protein 0.037 0.1617 0.2439
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0067 0.0086
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Plasmodium falciparum cysteine proteinase falcipain 3 0.0182 0.0735 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0212 0.0307
Echinococcus granulosus cathepsin L 0.0071 0.0212 0.0306
Onchocerca volvulus Cathepsin L homolog 0.0071 0.0212 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0029 0.0028
Plasmodium vivax vivapain-2 0.0182 0.0735 1
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Plasmodium vivax SET domain protein, putative 0.0032 0.0029 0.0247
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0015 0.001
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.121 0.7766
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0343 0.2227
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0102 0.0358 0.053
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0154 0.0603 0.0905
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Brugia malayi RNA binding protein 0.0128 0.0482 0.072
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) MBCTL1 0.0092 0.0312 0.046
Echinococcus granulosus serine protein kinase ATM 0.0051 0.0119 0.0164
Leishmania major C-8 sterol isomerase-like protein 0.0737 0.3344 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Echinococcus multilocularis zinc finger protein 0.0037 0.0051 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0067 0.0436
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0215 0.089 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0029 0.0024
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0064 0.0081
Brugia malayi Melatonin receptor type 1A 0.0029 0.0015 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus granulosus chromobox protein 1 0.0081 0.026 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0212 0.1374
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Echinococcus multilocularis GPCR, family 2 0.0032 0.0031 0.0031
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Echinococcus multilocularis histone acetyltransferase myst3 0.0043 0.0081 0.0107
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0064 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.6643
Loa Loa (eye worm) calpain family protein 1 0.004 0.0066 0.0086
Onchocerca volvulus 0.0095 0.0326 0.0473
Loa Loa (eye worm) jmjC domain-containing protein 0.0135 0.0515 0.0768
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0015 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0353 0.154 0.1536
Echinococcus granulosus tumor protein p63 0.0705 0.3191 0.4828
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0046 0.006
Loa Loa (eye worm) hypothetical protein 0.0048 0.0104 0.0144
Trypanosoma cruzi prolyl endopeptidase 0.0373 0.163 0.3607
Brugia malayi ORL1-like opioid receptor 0.0029 0.0015 0.0012
Schistosoma mansoni hypothetical protein 0.0824 0.3752 0.3749
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0358 0.053
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0067 0.0086
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0736 0.1102
Brugia malayi follicle stimulating hormone receptor 0.0252 0.1063 0.1603
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0015 0.0008
Mycobacterium ulcerans esterase/lipase LipP 0.0179 0.072 0.7977
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0179 0.072 0.1078
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0062
Plasmodium falciparum serine repeat antigen 3 0.0071 0.0212 0.2772
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0092 0.0312 0.0463
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0067 0.5
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0215 0.089 0.1963
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0212 0.2772
Echinococcus multilocularis cathepsin L cysteine protease 0.0182 0.0735 0.11
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0527 0.2356 0.3565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0113 0.0412 0.0609
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0067 0.0086
Loa Loa (eye worm) cysteine protease 0.0182 0.0735 0.1102
Brugia malayi RE15519p 0.0029 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Plasmodium falciparum transporter, putative 0.004 0.0067 0.0776
Schistosoma mansoni sex comb on midleg homolog 0.0255 0.1079 0.1075
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0985 0.4507 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.037 0.1617 0.1613
Brugia malayi AKH receptor 0.0029 0.0015 0.0012
Echinococcus granulosus allatostatin A receptor 0.0029 0.0015 0.0007
Entamoeba histolytica hypothetical protein, conserved 0.0139 0.0531 0.416
Echinococcus granulosus neuropeptide receptor 0.0029 0.0015 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.053 0.0958
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0139 0.0531 0.3446
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0179 0.072 0.0715
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0064 0.018 0.0257
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.012
Brugia malayi jmjC domain containing protein 0.0135 0.0515 0.0771
Schistosoma mansoni alpha-glucosidase 0.0141 0.0544 0.0539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0119 0.0771
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0353 0.154 0.4594
Trypanosoma cruzi aminopeptidase, putative 0.0036 0.0046 0.0087
Schistosoma mansoni hypothetical protein 0.0047 0.0099 0.0095
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0212 0.0207
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Toxoplasma gondii cathepsin CPL 0.0182 0.0735 0.3228
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0031 0.0037
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0087
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0139 0.0531 0.0526
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0116 0.0154
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.018 0.0262
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0015 0.0008
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0015 0.0007
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Toxoplasma gondii cathepsin CPC2 0.0071 0.0212 0.0846
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.053 0.5809
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.121 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0212 0.0311
Brugia malayi G-protein coupled receptor 0.0029 0.0015 0.0012
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Brugia malayi cathepsin L-like precursor 0.0182 0.0735 0.1105
Brugia malayi prolyl oligopeptidase family protein 0.0373 0.163 0.2463
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0482 0.0715
Echinococcus granulosus tar DNA binding protein 0.0128 0.0482 0.0715
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0139 0.0531 0.0526
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Mycobacterium tuberculosis Probable hydrolase 0.0179 0.072 0.1323
Loa Loa (eye worm) serotonin transporter b 0.0235 0.0984 0.1479
Loa Loa (eye worm) hypothetical protein 0.0527 0.2356 0.3562
Plasmodium falciparum serine repeat antigen 9 0.0071 0.0212 0.2772
Brugia malayi hypothetical protein 0.0037 0.0054 0.0072
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0071 0.0212 0.2772
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0015 0.0007
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0031 0.0031
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0047 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0531 0.3446
Loa Loa (eye worm) hypothetical protein 0.004 0.0066 0.0086
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.004 0.0065 0.0061
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Echinococcus multilocularis cysteine protease 0.0182 0.0735 0.11
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0015 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0182 0.0735 0.1094
Echinococcus granulosus caspase 2 0.0154 0.0604 0.0901
Toxoplasma gondii ABC1 family protein 0.0179 0.072 0.3157
Trypanosoma brucei prolyl endopeptidase 0.0373 0.163 0.1591
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0097
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0051 0.0119 0.0248
Schistosoma mansoni adenoreceptor 0.0029 0.0015 0.001
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0015 0.0007
Schistosoma mansoni hypothetical protein 0.0424 0.1872 0.1868
Echinococcus granulosus tumor suppressor p53 binding protein 1 0.0314 0.1357 0.2044
Toxoplasma gondii prolyl endopeptidase 0.0373 0.163 0.73
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.017 0.0165
Loa Loa (eye worm) hypothetical protein 0.0527 0.2356 0.3562
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0353 0.154 1
Schistosoma mansoni chromobox protein 0.0201 0.0823 0.0819
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0015 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Echinococcus multilocularis cysteine protease 0.0182 0.0735 0.11
Brugia malayi G protein-coupled receptor 0.0029 0.0015 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0054 0.0134 0.013
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0482 0.0717
Echinococcus granulosus cathepsin l1 0.0182 0.0735 0.11
Echinococcus granulosus serotonin transporter 0.0235 0.0984 0.1478
Brugia malayi calpain family protein 1 0.0054 0.0133 0.0191
Onchocerca volvulus 0.0247 0.1042 0.1561
Schistosoma mansoni chromobox protein 0.0081 0.026 0.0256
Brugia malayi cathepsin B-like cysteine proteinase 0.0985 0.4507 0.6827
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.305 0.3046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Schistosoma mansoni zinc finger protein 0.0037 0.0051 0.0046
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0031 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0051 0.033
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0015 0.0008
Trypanosoma brucei RNA helicase, putative 0.2154 1 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0154 0.0603 0.0559
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0051 0.033
Loa Loa (eye worm) hypothetical protein 0.006 0.0161 0.023
Schistosoma mansoni fkbp-rapamycin associated protein 0.0036 0.0049 0.0044
Loa Loa (eye worm) prolyl oligopeptidase 0.0139 0.0531 0.0791
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis serotonin transporter 0.0235 0.0984 0.1478
Schistosoma mansoni cpg binding protein 0.0048 0.0107 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0736 0.1103
Loa Loa (eye worm) hypothetical protein 0.0229 0.0957 0.1439
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0212 0.0307
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Echinococcus granulosus calpain A 0.0056 0.0144 0.0203
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0212 0.0454
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0737 0.3344 0.7416
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0067 0.0086
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0031 0.0033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0031 0.0031
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Loa Loa (eye worm) hypothetical protein 0.0034 0.0037 0.0042
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0182 0.0735 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Onchocerca volvulus 0.0034 0.0037 0.0034
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0092 0.0312 0.0458
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0051 0.033
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Schistosoma mansoni alpha-glucosidase 0.0141 0.0544 0.0539
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0179 0.072 0.1081
Brugia malayi cathepsin L-like cysteine proteinase 0.0071 0.0212 0.0311
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0046 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.0531 0.1163
Schistosoma mansoni cathepsin B (C01 family) 0.0071 0.0212 0.0207
Leishmania major oligopeptidase b 0.0215 0.089 0.2647
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.026 0.0381
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0019 0.0015
Loa Loa (eye worm) mbt repeat family protein 0.0266 0.1128 0.1698
Leishmania major hypothetical protein, conserved 0.0179 0.072 0.2135
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0064 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Schistosoma mansoni chromobox protein 0.0081 0.026 0.0256
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0042 0.0075 0.0226
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0527 0.2356 0.3565
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0038
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.0651 0.0974
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0068 0.0198 0.0152
Brugia malayi Bromodomain containing protein 0.0039 0.0062 0.0084
Brugia malayi Cell death protein 3 precursor 0.0154 0.0604 0.0906
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Schistosoma mansoni hypothetical protein 0.1194 0.549 0.5488
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0482 0.072
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0215 0.089 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0017 0.011
Echinococcus multilocularis serine protein kinase ATM 0.0051 0.0119 0.0164
Plasmodium falciparum serine repeat antigen 1 0.0071 0.0212 0.2772
Echinococcus granulosus dnaJ subfamily B 0.0424 0.1872 0.2826
Echinococcus multilocularis serotonin receptor 0.0029 0.0015 0.0007
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0604 0.0902
Trypanosoma cruzi hypothetical protein, conserved 0.0179 0.072 0.1583
Echinococcus multilocularis prolyl endopeptidase 0.0373 0.163 0.2459
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0071 0.0212 0.1374
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0737 0.3344 0.5063
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Toxoplasma gondii preprocathepsin c precursor, putative 0.0071 0.0212 0.0846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.0361 0.2346
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Plasmodium falciparum serine repeat antigen 7 0.0071 0.0212 0.2772
Schistosoma mansoni bromodomain containing protein 0.0081 0.026 0.0255
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0036 0.0046 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0067 0.0062
Brugia malayi Heterochromatin protein 1 0.0081 0.026 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0358 0.0534
Schistosoma mansoni caspase-7 (C14 family) 0.0154 0.0604 0.0599
Toxoplasma gondii non-specific serine/threonine protein kinase 0.004 0.0068 0.0193
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine proteinase 2 0.0071 0.0212 0.142
Schistosoma mansoni hypothetical protein 0.0314 0.1357 0.1353
Echinococcus granulosus muscleblind protein 0.0152 0.0594 0.0886
Echinococcus granulosus cathepsin L 0.0071 0.0212 0.0306
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0015 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0212 0.0166
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0046 0.0118
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.017 0.0656
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0154 0.0603 0.4784
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0067 0.0062
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Plasmodium vivax vivapain-3 0.0071 0.0212 0.2772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.0957 0.1437
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0126
Entamoeba histolytica protein kinase rad3, putative 0.0036 0.0049 0.002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0212 0.1374
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0099 0.0344 0.0506
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0383
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0015 0.0007
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0179 0.072 0.0715
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Giardia lamblia Alanyl dipeptidyl peptidase 0.0139 0.0531 0.3162
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0126
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0078
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0054 0.0066
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.143 0.6597 0.6596
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0099 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0472 0.3068
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Onchocerca volvulus 0.004 0.0067 0.0079
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0215 0.089 0.1963
Echinococcus multilocularis polycomb protein SCMH1 0.0255 0.1079 0.1623
Leishmania major phosphatidylinositol 3-kinase, putative 0.0064 0.018 0.0517
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Onchocerca volvulus 0.0179 0.072 0.1071
Plasmodium falciparum cysteine proteinase falcipain 1 0.0071 0.0212 0.2772
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0212 0.2772
Echinococcus multilocularis inhibitor of apoptosis protein 0.0527 0.2356 0.3561
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Echinococcus granulosus chromobox protein 1 0.0081 0.026 0.038
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0067 0.0062
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.011 0.0151
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Giardia lamblia Hypothetical protein 0.0071 0.0212 0.1
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0015 0.0012
Echinococcus multilocularis chromobox protein 2 0.0201 0.0823 0.1234
Echinococcus multilocularis chromobox protein 1 0.0081 0.026 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Plasmodium falciparum serine repeat antigen 4 0.0071 0.0212 0.2772
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0243 0.0353
Brugia malayi TAR-binding protein 0.0128 0.0482 0.072
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0139 0.0531 0.0486
Brugia malayi neuropeptide F receptor 0.0029 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0736 0.1102
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0215 0.089 0.2647
Echinococcus granulosus chromobox protein 2 0.0201 0.0823 0.1234
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0047 0.5
Brugia malayi Serotonin receptor 0.0029 0.0015 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0015 0.0007
Brugia malayi PHD-finger family protein 0.0042 0.0077 0.0106
Loa Loa (eye worm) solute carrier family 6 member 4 0.0235 0.0984 0.1479
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0235 0.0984 0.098
Echinococcus granulosus histone acetyltransferase MYST2 0.0092 0.0312 0.0458
Brugia malayi chromobox protein homolog 3 0.005 0.0116 0.0165
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0054 0.0049
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0092 0.0312 0.0458
Schistosoma mansoni hypothetical protein 0.0154 0.0604 0.0599
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0064 0.0081
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0358 0.0534
Toxoplasma gondii cathepsin B 0.0353 0.154 0.6889
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Brugia malayi hypothetical protein 0.024 0.101 0.1521
Echinococcus granulosus inhibitor of apoptosis protein 0.0527 0.2356 0.3561
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0022
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0154 0.0603 0.1786
Onchocerca volvulus Cell death protein 3 homolog 0.0154 0.0604 0.0895
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0089
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0064 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0066
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0051 0.0119 0.0073
Onchocerca volvulus 0.0036 0.0046 0.0048
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0071 0.0212 0.0454
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Loa Loa (eye worm) hypothetical protein 0.0103 0.0364 0.0539
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0047 0.0307
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0015 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0067 0.0086
Trypanosoma cruzi oligopeptidase b 0.0215 0.089 0.1963
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0036 0.0049 0.0058
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0071 0.0212 0.2772
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Echinococcus multilocularis cathepsin L 0.0071 0.0212 0.0306
Brugia malayi Inositol-1 0.0036 0.0047 0.0061
Brugia malayi larval opioid receptor 0.0029 0.0015 0.0012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0038
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0116 0.0752
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0182 0.0177
Loa Loa (eye worm) hypothetical protein 0.0152 0.0594 0.0887
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0317 0.0312
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0015 0.0008
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0015 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Loa Loa (eye worm) fibroinase 0.0182 0.0735 0.1102
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0736 0.1102
Loa Loa (eye worm) beta-lactamase 0.0179 0.072 0.1078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) phosphatidylinositol 3 0.0154 0.0603 0.0901
Onchocerca volvulus Prolyl endopeptidase homolog 0.0373 0.163 0.2454
Trypanosoma cruzi target of rapamycin kinase 3 0.0126 0.0473 0.1036
Trypanosoma cruzi hypothetical protein, conserved 0.0179 0.072 0.1583
Echinococcus granulosus polycomb protein SCMH1 0.0255 0.1079 0.1623
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0212 0.142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Schistosoma mansoni inhibitor of apoptosis protein 0.0527 0.2356 0.2353
Schistosoma mansoni cathepsin C 0.0071 0.0212 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0002 0.0015
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0041 0.0072 0.0094
Echinococcus granulosus prolyl endopeptidase 0.0373 0.163 0.2459
Onchocerca volvulus 0.0031 0.0024 0.0014
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.017 0.0242
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0015 0.0007
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0054 0.0133 0.0128
Loa Loa (eye worm) hypothetical protein 0.0154 0.0604 0.0902
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0064 0.017
Brugia malayi Dopamine receptor protein 2 0.0029 0.0015 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Toxoplasma gondii FATC domain-containing protein 0.0051 0.0119 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Giardia lamblia Hypothetical protein 0.0071 0.0212 0.1
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0015 0.0008
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0527 0.2356 0.3561
Echinococcus granulosus sex peptide receptor 0.0029 0.0015 0.0007
Brugia malayi mbt repeat family protein 0.0266 0.1128 0.1701
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0047 0.0007
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0212 0.0454
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0071 0.0212 0.2772
Trypanosoma cruzi cysteine proteinase, putative 0.0071 0.0212 0.0454
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.4926
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0161 0.0617
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Onchocerca volvulus 0.004 0.0067 0.0079
Loa Loa (eye worm) hypothetical protein 0.0377 0.165 0.2491
Loa Loa (eye worm) hypothetical protein 0.0092 0.0312 0.046
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0015 0.0007
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0041 0.0075 0.007
Schistosoma mansoni sodium/chloride dependent transporter 0.0235 0.0984 0.098
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0015 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0179 0.072 0.1323
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0015 0.0007
Onchocerca volvulus 0.0182 0.0735 0.1094
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0182 0.0735 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.004 0.0065 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0064 0.0059
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0099 0.0344 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0049 0.006
Brugia malayi Pre-SET motif family protein 0.0217 0.0901 0.1357
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis histone acetyltransferase MYST2 0.0092 0.0312 0.0458
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Toxoplasma gondii target of rapamycin (TOR), putative 0.0119 0.044 0.1885
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0071 0.0212 0.0207
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0071 0.0212 0.2772
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0139 0.0531 0.416
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0047 0.0307
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1142 0.5246 1
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0501 0.2233 0.3374
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0067 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0053 0.013 0.0843
Brugia malayi Bromodomain containing protein 0.0093 0.0316 0.0469
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0015 0.0007
Giardia lamblia Alanyl dipeptidyl peptidase 0.0139 0.0531 0.3162
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0036 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.005 0.0116 0.0162
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0373 0.163 0.1626
Schistosoma mansoni hypothetical protein 0.0037 0.0054 0.0049
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0015 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.018 0.0258
Plasmodium vivax hypothetical protein, conserved 0.004 0.0067 0.0776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0139 0.0531 0.2297
Loa Loa (eye worm) hypothetical protein 0.024 0.101 0.1518
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0015 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0071 0.0212 0.0311
Trypanosoma brucei glucosidase, putative 0.0036 0.0051 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Plasmodium falciparum serine repeat antigen 5 0.0071 0.0212 0.2772
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.121 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus Dipeptidyl peptidase 9 0.0499 0.2224 0.336
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0215 0.089 0.0848
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Echinococcus granulosus histone acetyltransferase myst3 0.0043 0.0081 0.0107
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0071 0.0212 0.2772
Toxoplasma gondii PLU-1 family protein 0.0042 0.0078 0.0238
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0089
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0036 0.0049 0.0092
Echinococcus granulosus geminin 0.1194 0.549 0.8319
Plasmodium falciparum serine repeat antigen 2 0.0071 0.0212 0.2772
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0212 0.2772
Plasmodium falciparum peptidase, putative 0.0139 0.0531 0.7176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis esterase, putative 0.0179 0.072 0.4673
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis tumor suppressor p53 binding protein 1 0.0314 0.1357 0.2044
Brugia malayi hypothetical protein 0.0036 0.0046 0.006
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0373 0.163 0.1626
Schistosoma mansoni cpg binding protein 0.0048 0.0107 0.0102
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0212 0.0207
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0234 0.0979 0.182
Schistosoma mansoni survival motor neuron protein 0.0047 0.0099 0.0095
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0033
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0985 0.4507 0.4504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi prolyl oligopeptidase family protein 0.0499 0.2224 0.3364
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0047 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0015 0.0007
Schistosoma mansoni hypothetical protein 0.007 0.0207 0.0202
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Loa Loa (eye worm) transcription factor SMAD2 0.0353 0.1537 0.2319
Echinococcus multilocularis tumor protein p63 0.0705 0.3191 0.4828
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0015 0.0007
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Echinococcus granulosus GPCR family 2 0.0032 0.0031 0.0031
Echinococcus granulosus aminopeptidase N 0.0036 0.0046 0.0055
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0207 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0049 0.0317
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0051 0.0063
Trichomonas vaginalis set domain proteins, putative 0.0247 0.1042 0.6767
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0139 0.0531 0.3446
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0036 0.0049 0.002
Onchocerca volvulus 0.0054 0.0134 0.0182
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0736 0.1106
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0047 0.0098
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0235 0.0984 0.1483
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0064 0.0416
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0154 0.0603 0.0599
Brugia malayi prolyl oligopeptidase family protein 0.0139 0.0531 0.0795
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0071 0.0212 0.2772
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0152 0.0594 0.0887
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0015 0.001
Echinococcus multilocularis calpain A 0.0056 0.0144 0.0203
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0015 0.001
Echinococcus granulosus cathepsin L cysteine proteinase 0.0182 0.0735 0.11
Schistosoma mansoni sex comb on midleg homolog 0.0255 0.1079 0.1075
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Mycobacterium leprae Probable lipase LipE 0.0179 0.072 0.8016
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0051 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0049 0.0064
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0499 0.2224 0.222
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0056 0.0144 0.0203
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Plasmodium vivax vivapain-2 0.0182 0.0735 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.017 0.0487
Schistosoma mansoni inositol monophosphatase 0.0036 0.0047 0.0043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis somatostatin receptor 0.0029 0.0015 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0015 0.0007
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0068 0.0199 0.0153
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0527 0.2356 0.2353
Onchocerca volvulus 0.0182 0.0735 0.1094
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0264 0.1119 0.1115
Echinococcus granulosus cathepsin b 0.0985 0.4507 0.6826
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0342 0.2221
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0126 0.0473 0.0429
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.013 0.0175
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.014
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) prolyl oligopeptidase 0.143 0.6597 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0071 0.0212 0.0207
Entamoeba histolytica hypothetical protein 0.0071 0.0212 0.142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Brugia malayi MH2 domain containing protein 0.0353 0.1537 0.2322
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0179 0.072 0.7977
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Brugia malayi mbt repeat family protein 0.0439 0.1944 0.2939
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Plasmodium vivax amine transporter, putative 0.004 0.0067 0.0776
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0353 0.154 0.3407
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0046 0.0301
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Echinococcus multilocularis cathepsin L 0.0071 0.0212 0.0306
Brugia malayi hypothetical protein 0.004 0.0067 0.0091
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0182 0.0735 0.1618
Trichomonas vaginalis chromobox protein, putative 0.0081 0.026 0.1691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0179 0.072 0.1323
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus apoptotic protease activating factor 1 0.0154 0.0604 0.0901
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0064 0.0059
Brugia malayi Subtilase family protein 0.0264 0.1119 0.1687
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0067 0.0091
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0015 0.0007
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Schistosoma mansoni cpg binding protein 0.003 0.0019 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Loa Loa (eye worm) hypothetical protein 0.0072 0.0217 0.0315
Echinococcus granulosus cysteine protease 0.0071 0.0212 0.0306
Loa Loa (eye worm) CHromoDomain protein family member 0.0041 0.0072 0.0096
Onchocerca volvulus 0.0154 0.0604 0.0895
Trypanosoma brucei oligopeptidase b 0.0215 0.089 0.0848
Loa Loa (eye worm) ctsf protein 0.0182 0.0735 0.1102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0364 0.036
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0015 0.001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0015 0.0007
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0824 0.3752 0.568
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.2187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0015 0.0007
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Trypanosoma brucei prolyl oligopeptidase, putative 0.0215 0.089 0.0848
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0015 0.0007
Toxoplasma gondii hypothetical protein 0.0139 0.0531 0.2297
Trypanosoma cruzi Aminopeptidase M1, putative 0.0036 0.0046 0.0087
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0015 0.0007
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0071 0.0212 0.2772
Mycobacterium ulcerans lipase LipD 0.0179 0.072 0.7977
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0041 0.0072 0.0094
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.143 0.6597 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Echinococcus multilocularis caspase 2 0.0154 0.0604 0.0901
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Echinococcus granulosus zinc finger protein 0.0037 0.0051 0.0062
Echinococcus granulosus beta LACTamase domain containing family member 0.0179 0.072 0.1077
Schistosoma mansoni cathepsin S (C01 family) 0.0071 0.0212 0.0207
Onchocerca volvulus 0.0182 0.0735 0.1094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Trichomonas vaginalis penicillin-binding protein, putative 0.0179 0.072 0.4673
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Onchocerca volvulus 0.0071 0.0212 0.0299
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0051 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0049 0.0317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0252 0.1063 0.1599
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0064 0.0087
Plasmodium vivax unspecified product 0.0071 0.0212 0.2772
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0736 0.1102
Brugia malayi Dopamine receptor 0.0029 0.0015 0.0012
Echinococcus granulosus fmrfamide receptor 0.0029 0.0015 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Schistosoma mansoni hypothetical protein 0.0527 0.2356 0.2353
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0067 0.0086
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.121 1
Echinococcus granulosus cpg binding protein 0.0048 0.0107 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) aminopeptidase N 0.0036 0.0046 0.0056
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Entamoeba histolytica cysteine protease, putative 0.0182 0.0735 0.5918
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0064 0.018 0.0175
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus multilocularis muscleblind protein 0.0152 0.0594 0.0886
Echinococcus granulosus hypothetical protein 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Schistosoma mansoni myosin xvIII 0.0029 0.0015 0.001
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0015 0.001
Echinococcus granulosus neuropeptide receptor 0.0029 0.0015 0.0007
Onchocerca volvulus 0.0103 0.0364 0.0531
Brugia malayi cathepsin F-like cysteine proteinase 0.0071 0.0212 0.0311
Echinococcus multilocularis aminopeptidase N 0.0036 0.0046 0.0055
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0015 0.001
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Brugia malayi prolyl oligopeptidase family protein 0.143 0.6597 1
Brugia malayi beta-lactamase 0.0179 0.072 0.1081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Plasmodium vivax unspecified product 0.0071 0.0212 0.2772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0134
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0243 0.0353
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0901 0.1354
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0154 0.0603 0.1786
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0051 0.0067
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus granulosus cathepsin b 0.0985 0.4507 0.6826
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.017 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0064 0.0416
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0383
Brugia malayi sulfakinin receptor protein 0.024 0.101 0.1521
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0062
Echinococcus multilocularis chromobox protein 1 0.0081 0.026 0.038
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0154 0.0603 0.1325
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0064 0.0151
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0015 0.0008
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Loa Loa (eye worm) hypothetical protein 0.0985 0.4507 0.6826
Onchocerca volvulus 0.0036 0.0046 0.0048
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0179 0.072 0.1323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Onchocerca volvulus Cathepsin F homolog 0.0182 0.0735 0.1094
Brugia malayi neuropeptide F receptor 0.0029 0.0015 0.0012
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0031 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0054 0.0066
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0071 0.0212 0.2772
Echinococcus multilocularis sex peptide receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0053 0.013 0.0843
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.017 0.0242
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0031 0.0031
Brugia malayi hypothetical protein 0.0154 0.0604 0.0906
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0015 0.0007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0067 0.0062
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0015 0.0008
Onchocerca volvulus 0.0182 0.0735 0.1094
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.143 0.6597 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0071 0.0212 0.2772
Mycobacterium leprae conserved hypothetical protein 0.0179 0.072 0.8016
Loa Loa (eye worm) subtilase 0.0264 0.1119 0.1684
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0212 0.0166
Brugia malayi hypothetical protein 0.0229 0.0957 0.1442
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0439 0.1944 0.293
Plasmodium vivax hypothetical protein, conserved 0.0139 0.0531 0.7176
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0002 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0015 0.0007
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0116 0.0752
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.0651 0.0978
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Schistosoma mansoni phd finger protein 0.0043 0.0081 0.0076
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0071 0.0212 0.2772
Toxoplasma gondii hypothetical protein 0.004 0.0067 0.0188
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0036 0.0049 0.0058
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Onchocerca volvulus 0.0179 0.072 0.1071
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0139 0.0531 0.0791
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Entamoeba histolytica hypothetical protein 0.0051 0.0119 0.0621
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0015 0.0012
Schistosoma mansoni inositol monophosphatase 0.0036 0.0047 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0068
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0317 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.0531 0.1163
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0501 0.2233 0.3374
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0594 0.0886
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0182 0.0735 0.1102
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0066 0.0085
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Plasmodium falciparum serine repeat antigen 8 0.0071 0.0212 0.2772
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0015 0.001
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.143 0.6597 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Mycobacterium ulcerans hypothetical protein 0.0179 0.072 0.7977
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0071 0.0212 0.0307
Giardia lamblia Cathepsin L-like protease 0.0071 0.0212 0.1
Mycobacterium tuberculosis Probable peptidase 0.0215 0.089 0.165
Brugia malayi CHD4 protein 0.0041 0.0072 0.01
Onchocerca volvulus 0.0179 0.072 0.1071
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0067 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0154 0.0603 0.4784
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0015 0.0012
Echinococcus multilocularis acylamino acid releasing enzyme 0.0139 0.0531 0.079
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi Muscleblind-like protein 0.0152 0.0594 0.089
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0015 0.0007
Plasmodium falciparum serine repeat antigen 6 0.0071 0.0212 0.2772
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus granulosus lysine specific demethylase 5A 0.0093 0.0317 0.0465
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0015 0.0007
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Brugia malayi G-protein coupled receptor 0.0029 0.0015 0.0012
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0215 0.089 0.165
Trypanosoma cruzi cruzipain precursor, putative 0.0182 0.0735 0.1618
Loa Loa (eye worm) hypothetical protein 0.004 0.0068 0.0089
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0071 0.0212 0.1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0064 0.018 0.0134
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.0203
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0015 0.0007
Brugia malayi calpain family protein 1 0.0054 0.0133 0.0191
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0041 0.0072 0.0068
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0119 0.017
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0015 0.0007
Mycobacterium tuberculosis Probable esterase LipL 0.0179 0.072 0.1323
Echinococcus multilocularis cathepsin L cysteine protease 0.0182 0.0735 0.11
Entamoeba histolytica cysteine proteinase 1, putative 0.0071 0.0212 0.142
Onchocerca volvulus 0.0182 0.0735 0.1094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Giardia lamblia GTOR 0.0154 0.0603 0.3653
Echinococcus granulosus fetal alzheimer antigen falz 0.004 0.0065 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0015 0.0007
Trypanosoma brucei C-8 sterol isomerase, putative 0.0737 0.3344 0.3313
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0527 0.2356 0.3561
Loa Loa (eye worm) MH2 domain-containing protein 0.0353 0.1537 0.2319
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus serotonin receptor 0.0029 0.0015 0.0007
Brugia malayi Serotonin receptor 0.0029 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.03
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0039 0.0061 0.012
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0113 0.0412 0.0609
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0015 0.0007
Onchocerca volvulus 0.0182 0.0735 0.1094
Trypanosoma cruzi cysteine proteinase, putative 0.0071 0.0212 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Toxoplasma gondii hypothetical protein 0.004 0.0067 0.0188
Loa Loa (eye worm) calpain family protein 1 0.0054 0.0133 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Brugia malayi beta-lactamase family protein 0.0179 0.072 0.1081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0343 0.2227
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0046 0.0301
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0098
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0071 0.0212 0.2772
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Schistosoma mansoni hypothetical protein 0.0028 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Mycobacterium ulcerans beta-lactamase 0.0179 0.072 0.7977
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0051 0.0119 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni myelin transcription factor 1 myt1 0.0092 0.0312 0.0308
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.002 0.0015
Echinococcus multilocularis cathepsin b 0.0985 0.4507 0.6826
Echinococcus multilocularis beta LACTamase domain containing family member 0.0179 0.072 0.1077
Echinococcus granulosus cathepsin l1 0.0182 0.0735 0.11
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0036 0.0046 0.0055
Echinococcus multilocularis geminin 0.1194 0.549 0.8319
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Onchocerca volvulus 0.0182 0.0735 0.1094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0001
Onchocerca volvulus 0.0047 0.0099 0.0128
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0154 0.0603 0.09
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Schistosoma mansoni histamine h1 receptor 0.0029 0.0015 0.001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.1872 0.2826
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.011 0.0106
Onchocerca volvulus 0.0235 0.0984 0.1472
Brugia malayi prolyl oligopeptidase family protein 0.0139 0.0531 0.0795
Plasmodium vivax vivapain-1 0.0071 0.0212 0.2772
Echinococcus multilocularis cpg binding protein 0.0048 0.0107 0.0146
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0015 0.0007
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus granulosus microtubule associated protein 2 0.0675 0.305 0.4614
Echinococcus multilocularis serotonin receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0154 0.0603 0.1325
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0126 0.0473 0.1397
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0154 0.0603 0.09
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0182 0.0735 0.1102
Onchocerca volvulus 0.0527 0.2356 0.3557
Onchocerca volvulus Cathepsin L homolog 0.0182 0.0735 0.1094
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0015 0.001
Brugia malayi beta-lactamase family protein 0.0179 0.072 0.1081
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.053 0.5726
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi putative neuropeptide receptor 0.0029 0.0015 0.0012
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0114
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Loa Loa (eye worm) hypothetical protein 0.0054 0.0133 0.0187
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0212 0.142
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Brugia malayi Papain family cysteine protease containing protein 0.0182 0.0735 0.1105
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0442
Loa Loa (eye worm) hypothetical protein 0.0049 0.011 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0017 0.011
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0015 0.0008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.017 0.0269
Plasmodium falciparum amino acid transporter, putative 0.004 0.0067 0.0776

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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