Detailed information for compound 133397

Basic information

Technical information
  • TDR Targets ID: 133397
  • Name: (3R,4R,5S)-4-acetamido-5-(diaminomethylidenea mino)-3-propoxycyclohexene-1-carboxylic acid
  • MW: 298.338 | Formula: C13H22N4O4
  • H donors: 4 H acceptors: 3 LogP: -1.19 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCO[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N=C(N)N)C(=O)O
  • InChi: 1S/C13H22N4O4/c1-3-4-21-10-6-8(12(19)20)5-9(17-13(14)15)11(10)16-7(2)18/h6,9-11H,3-5H2,1-2H3,(H,16,18)(H,19,20)(H4,14,15,17)/t9-,10+,11+/m0/s1
  • InChiKey: JPGVNBPJSYNZSP-HBNTYKKESA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3R,4R,5S)-4-acetamido-5-guanidino-3-propoxy-cyclohexene-1-carboxylic acid
  • (3R,4R,5S)-4-acetamido-5-guanidino-3-propoxy-1-cyclohexenecarboxylic acid
  • (3R,4R,5S)-4-acetamido-5-[bis(azanyl)methylideneamino]-3-propoxy-cyclohexene-1-carboxylic acid
  • (3R,4R,5S)-4-acetamido-5-(diaminomethylideneamino)-3-propoxy-cyclohexene-1-carboxylic acid
  • (3R,4R,5S)-4-Acetylamino-5-guanidino-3-propoxy-cyclohex-1-enecarboxylic acid
  • AIDS-123635
  • AIDS123635
  • Carbocyclic Analogue 59

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Neuraminidase Starlite/ChEMBL References
Influenza A virus Neuraminidase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Theileria parva ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Cryptosporidium parvum ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma brucei gambiense ubiquitin-conjugating enzyme e2, putative,ubiquitin carrier protein, putative,ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium knowlesi ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium berghei ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans ubiquitin conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Babesia bovis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Neospora caninum Ubiquitin carrier protein (EC 6.3.2.-), related Get druggable targets OG5_127739 All targets in OG5_127739
Cryptosporidium hominis ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Schistosoma mansoni ubiquitin conjugating enzyme 13 Get druggable targets OG5_127739 All targets in OG5_127739
Entamoeba histolytica ubiquitin-conjugating enzyme family protein Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Schistosoma japonicum ko:K10580 ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania major ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania donovani ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma congolense ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma brucei ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania mexicana ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Echinococcus granulosus ubiquitin conjugating enzyme E2 N Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania braziliensis ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans post-replication repair Get druggable targets OG5_127739 All targets in OG5_127739
Brugia malayi Ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Brugia malayi ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0096 0.0278
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0002 0.0001
Toxoplasma gondii ABC1 family protein 0.0523 0.0996 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0123 0.0192 0.063
Brugia malayi jmjC domain containing protein 0.0122 0.0189 0.0621
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0123 0.0192 0.0191
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0116 0.0178 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1044 0.2043 0.2042
Mycobacterium tuberculosis Probable dehydrogenase 0.0678 0.1308 0.1962
Loa Loa (eye worm) hypothetical protein 0.0098 0.0142 0.0472
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0019 0.0074
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0116 0.0178 1
Trichomonas vaginalis esterase, putative 0.0523 0.0996 0.2894
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0108 0.0161 0.0531
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0123 0.0192 0.0636
Schistosoma mansoni ran 0.0066 0.0076 0.0253
Echinococcus granulosus mothers against decapentaplegic 5 0.0059 0.0062 0.0203
Schistosoma mansoni ferritin 0.0028 0.0001 0.0003
Toxoplasma gondii hypothetical protein 0.0197 0.034 0.3405
Trypanosoma cruzi ISWI complex protein 0.0062 0.0069 0.028
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0058 0.0061 0.0078
Trypanosoma brucei importin beta-1 subunit, putative 0.0089 0.0124 0.0509
Echinococcus granulosus zinc finger protein 0.009 0.0124 0.041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0105
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0103 0.0151 0.015
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0045 0.0034 0.0114
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0252 0.0451 0.045
Brugia malayi glutathione reductase 0.0297 0.0542 0.1794
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1527 0.3015 1
Brugia malayi RNA binding protein 0.0063 0.0071 0.0232
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.0077
Loa Loa (eye worm) steroid hormone receptor 0.0123 0.0192 0.0636
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0065 0.0075 0.0074
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0045 0.0034 0.0111
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Echinococcus granulosus ecdysone induced protein 78C 0.0123 0.0192 0.0632
Brugia malayi ERG2 and Sigma1 receptor like protein 0.109 0.2135 0.7081
Entamoeba histolytica hypothetical protein 0.023 0.0407 1
Schistosoma mansoni cpg binding protein 0.012 0.0187 0.0619
Loa Loa (eye worm) hypothetical protein 0.0247 0.0441 0.1463
Schistosoma mansoni smad 0.0059 0.0062 0.0206
Brugia malayi PHD-finger family protein 0.0043 0.0032 0.01
Echinococcus granulosus nuclear receptor nhr 48 0.0058 0.0061 0.0199
Loa Loa (eye worm) hypothetical protein 0.0065 0.0075 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0123 0.0192 0.063
Trichomonas vaginalis bromodomain-containing protein, putative 0.0052 0.0049 0.0139
Brugia malayi follicle stimulating hormone receptor 0.0706 0.1363 0.4519
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0045 0.0034 0.0097
Schistosoma mansoni smad1 5 8 and 0.0059 0.0062 0.0206
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.002 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.007 0.0232
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.002 0.0029
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0019 0.0061
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0123 0.0192 0.0636
Brugia malayi hypothetical protein 0.0247 0.0441 0.1458
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1221 0.2398 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.023 0.0407 0.1347
Schistosoma mansoni hypothetical protein 0.0442 0.0832 0.276
Brugia malayi Importin beta-1 subunit 0.0089 0.0124 0.0405
Schistosoma mansoni bromodomain containing protein 0.0266 0.048 0.1593
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0114
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0002 0.0001
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0002 0.0006
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.003 0.0095
Onchocerca volvulus 0.012 0.0187 0.0447
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0045 0.0034 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Schistosoma mansoni ap endonuclease 0.0116 0.0178 0.059
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0052 0.0049 0.0473
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0019 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0017 0.0156
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0203 0.0353 0.1165
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0123 0.0192 0.0632
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.029 0.0528 0.1752
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0045 0.0034 0.0114
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0032 0.0031
Brugia malayi AF-10 protein 0.0029 0.0002 0.0002
Brugia malayi nuclear receptor RXR 0.0065 0.0075 0.0243
Echinococcus multilocularis survival motor neuron protein 1 0.0996 0.1947 0.1946
Loa Loa (eye worm) nuclear receptor NHR-67 0.0058 0.0061 0.0202
Brugia malayi exodeoxyribonuclease III family protein 0.0116 0.0178 0.0585
Schistosoma mansoni hypothetical protein 0.0411 0.077 0.2554
Brugia malayi hypothetical protein 0.0996 0.1947 0.6456
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0032 0.0089
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0096 0.1992
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0159 0.2905
Mycobacterium tuberculosis Probable lipase LipD 0.0523 0.0996 0.1493
Echinococcus granulosus neuropeptide receptor A26 0.0476 0.0901 0.2988
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.009 0.0258
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0103 0.0151 0.1507
Brugia malayi PHD-finger family protein 0.0111 0.0168 0.0552
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0022 0.0082
Onchocerca volvulus Serine\/threonine kinase homolog 0.0108 0.0161 0.0372
Brugia malayi N-terminal motif family protein 0.0371 0.069 0.2286
Schistosoma mansoni thyroid hormone receptor 0.0404 0.0757 0.2511
Schistosoma mansoni coup transcription factor 0.0123 0.0192 0.0636
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0046 0.0037 0.0036
Loa Loa (eye worm) fli-1 protein 0.0252 0.0451 0.1497
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Echinococcus multilocularis dna polymerase eta 0.0063 0.007 0.0069
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0019 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0523 0.0996 0.1493
Entamoeba histolytica hypothetical protein 0.023 0.0407 1
Loa Loa (eye worm) MH2 domain-containing protein 0.086 0.1672 0.5548
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0096 0.0395
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0022 0.0383
Echinococcus granulosus mixed lineage leukemia protein mll 0.0038 0.0021 0.0065
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0123 0.0192 0.0636
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0052 0.0049 0.0473
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0002 0.0006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.002 0.0066
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0143 0.0142
Plasmodium falciparum thioredoxin reductase 0.0103 0.0151 0.2772
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0123 0.0192 0.0632
Trichomonas vaginalis mercuric reductase, putative 0.0103 0.0151 0.0438
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0058 0.0061 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0019 0.0053
Schistosoma mansoni glutaminase 0.0566 0.1082 0.359
Loa Loa (eye worm) hypothetical protein 0.0148 0.0241 0.08
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0096 0.0395
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0076 0.0096 0.0315
Schistosoma mansoni thyroid hormone receptor 0.0404 0.0757 0.2511
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0289 0.12
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0103 0.0151 0.0625
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0186 0.1497
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0032 0.0323
Loa Loa (eye worm) DR-78 0.0058 0.0061 0.0202
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0045 0.0034 0.0114
Schistosoma mansoni hypothetical protein 0.0041 0.0027 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0123 0.0192 0.0636
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0123 0.0192 0.063
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0172 0.0289 0.12
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Onchocerca volvulus 0.0523 0.0996 0.2824
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0096 0.0317
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.0161 0.0665
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0148 0.0242 0.0802
Schistosoma mansoni alpha-glucosidase 0.0144 0.0235 0.0779
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0173 0.0293 0.0969
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0123 0.0192 0.0191
Loa Loa (eye worm) Smad1 0.0059 0.0062 0.0206
Loa Loa (eye worm) hypothetical protein 0.0088 0.0122 0.0405
Loa Loa (eye worm) hypothetical protein 0.0557 0.1064 0.353
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.002 0.0066
Brugia malayi ImpB/MucB/SamB family protein 0.0063 0.007 0.0227
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.002 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0123 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Echinococcus multilocularis GPCR, family 2 0.0411 0.077 0.0769
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0046 0.0037 0.0122
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0123 0.0192 0.063
Echinococcus granulosus survival motor neuron protein 1 0.0996 0.1947 0.6458
Loa Loa (eye worm) hypothetical protein 0.109 0.2135 0.7082
Loa Loa (eye worm) hypothetical protein 0.0065 0.0075 0.0249
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0045 0.0034 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0071 0.0232
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0045 0.0034 0.0097
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.029 0.0526 0.0525
Trypanosoma brucei PAB1-binding protein , putative 0.0107 0.0159 0.0655
Echinococcus multilocularis geminin 0.1081 0.2118 0.2117
Schistosoma mansoni methyl-cpg binding protein mbd 0.0069 0.0083 0.0275
Echinococcus granulosus smad 0.0059 0.0062 0.0203
Loa Loa (eye worm) histone methyltransferase 0.0045 0.0035 0.0117
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0211 0.0368 0.1217
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0678 0.1308 0.1962
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Onchocerca volvulus 0.1738 0.3438 1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0045 0.0034 0.0114
Loa Loa (eye worm) solute carrier family 6 member 4 0.0148 0.0241 0.08
Brugia malayi mbt repeat family protein 0.0152 0.025 0.0826
Loa Loa (eye worm) hypothetical protein 0.0183 0.0312 0.1036
Brugia malayi hypothetical protein 0.0045 0.0034 0.0109
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0952 0.1859 0.6166
Echinococcus granulosus Protein patched homolog 1 0.0042 0.003 0.0095
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0123 0.0192 0.0636
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.0077
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0046 0.0037 0.0147
Echinococcus granulosus GA binding protein alpha chain 0.0083 0.0111 0.0366
Brugia malayi latrophilin 2 splice variant baaae 0.0887 0.1728 0.5729
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0071 0.0237
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.003 0.0029
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0038 0.0021 0.002
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0242 0.0802
Brugia malayi ecdysone receptor 0.0058 0.0061 0.0197
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0076 0.1381
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0036 0.0017 0.0287
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0122 0.1211
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0105
Trypanosoma cruzi trypanothione reductase, putative 0.0297 0.0542 0.2255
Loa Loa (eye worm) glutaminase 2 0.0566 0.1082 0.3589
Schistosoma mansoni steroid hormone receptor ad4bp 0.0123 0.0192 0.0636
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0103 0.0151 0.0502
Echinococcus multilocularis histone acetyltransferase MYST2 0.0173 0.0293 0.0292
Echinococcus multilocularis neuropeptide receptor A26 0.0476 0.0901 0.09
Echinococcus granulosus fetal alzheimer antigen falz 0.0098 0.0142 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0052 0.0147
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1221 0.2398 1
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0045 0.0034 0.0109
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0052 0.0049 0.0139
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0252 0.0451 0.1493
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0032 0.0102
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0077
Echinococcus granulosus phd:f box containing protein 0.0029 0.0002 0.0002
Schistosoma mansoni ran 0.0066 0.0076 0.0253
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0123 0.0192 0.0632
Loa Loa (eye worm) hypothetical protein 0.0411 0.077 0.2553
Echinococcus granulosus dna polymerase kappa 0.0038 0.002 0.0063
Mycobacterium tuberculosis Conserved hypothetical protein 0.0643 0.1237 0.1856
Plasmodium falciparum glutathione reductase 0.0103 0.0151 0.2772
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0103 0.0151 0.0499
Brugia malayi beta-lactamase 0.0523 0.0996 0.3299
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0002 0.0006
Plasmodium falciparum thioredoxin reductase 0.0297 0.0542 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0523 0.0996 0.3303
Brugia malayi Bromodomain containing protein 0.0314 0.0575 0.1904
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0085 0.0346
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0019 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0186 0.1497
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Brugia malayi G-protein alpha subunit 0.0045 0.0034 0.0109
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0114
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0061 0.0202
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0045 0.0034 0.0109
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0103 0.0151 0.1217
Echinococcus granulosus histone lysine methyltransferase setb 0.029 0.0528 0.1749
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0046 0.0037 0.0457
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Schistosoma mansoni hypothetical protein 0.0062 0.0069 0.0228
Schistosoma mansoni GTP-binding protein alpha subunit 0.0045 0.0034 0.0114
Loa Loa (eye worm) PHD-finger family protein 0.0088 0.0122 0.0405
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0032 0.0105
Echinococcus multilocularis dna polymerase kappa 0.0038 0.002 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0237
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0103 0.0151 0.0625
Loa Loa (eye worm) hypothetical protein 0.0052 0.0049 0.0162
Loa Loa (eye worm) MH1 domain-containing protein 0.0059 0.0062 0.0206
Loa Loa (eye worm) jmjC domain-containing protein 0.0122 0.0189 0.0626
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0237
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0253 0.0834
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0045 0.0034 0.0114
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0032 0.0125
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0046 0.0037 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Brugia malayi steroid hormone receptor 0.0123 0.0192 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Echinococcus multilocularis PHD finger protein rhinoceros 0.0088 0.0122 0.0121
Loa Loa (eye worm) nuclear factor I 0.0032 0.0009 0.0031
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0058 0.0061 0.006
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0046 0.0037 0.0122
Trypanosoma brucei hypothetical protein, conserved 0.0523 0.0996 0.4148
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0096 0.0095
Schistosoma mansoni jumonji domain containing protein 0.023 0.0407 0.135
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0076 0.0248
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.008 0.0119
Loa Loa (eye worm) hypothetical protein 0.0152 0.0249 0.0826
Echinococcus granulosus Nuclear hormone receptor HR96 0.0058 0.0061 0.0199
Brugia malayi beta-lactamase family protein 0.0523 0.0996 0.3299
Schistosoma mansoni sex comb on midleg homolog 0.0152 0.025 0.0831
Brugia malayi Thioredoxin reductase 0.0297 0.0542 0.1794
Schistosoma mansoni apoferritin-2 0.0028 0.0001 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0032 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1298 0.2553 0.8469
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0032 0.0105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0411 0.077 0.2551
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0123 0.0192 0.063
Echinococcus multilocularis GA binding protein alpha chain 0.0083 0.0111 0.011
Loa Loa (eye worm) PHD-finger family protein 0.0084 0.0112 0.0372
Leishmania major hypothetical protein, conserved 0.0523 0.0996 0.4148
Brugia malayi Steroid receptor seven-up type 2 0.0123 0.0192 0.063
Loa Loa (eye worm) glutaminase 0.0566 0.1082 0.3589
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0061 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0063 0.0071 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0123 0.0192 0.063
Brugia malayi conserved hypotetical protein 0.0058 0.0061 0.0197
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0002 0.0006
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0046 0.0037 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0052 0.0147
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0045 0.0034 0.0109
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0076 0.0311
Loa Loa (eye worm) jmjC domain-containing protein 0.0183 0.0311 0.1033
Echinococcus granulosus PHD finger protein rhinoceros 0.0088 0.0122 0.0402
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0085 0.0346
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0058 0.0061 0.0202
Brugia malayi CHE-14 protein 0.0042 0.003 0.0093
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0221 0.0389 0.1291
Plasmodium vivax SET domain protein, putative 0.0221 0.0389 0.3899
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0045 0.0034 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1044 0.2043 0.6777
Echinococcus granulosus FTZ F1 alpha 0.0123 0.0192 0.0632
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0076 0.0253
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0043 0.0031 0.01
Schistosoma mansoni inositol monophosphatase 0.0076 0.0096 0.032
Leishmania major hypothetical protein, conserved 0.0062 0.0069 0.028
Schistosoma mansoni importin beta-1 0.0089 0.0124 0.041
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0173 0.0293 0.0292
Trypanosoma brucei C-8 sterol isomerase, putative 0.109 0.2135 0.8902
Brugia malayi nuclear receptor NHR-88 0.0123 0.0192 0.063
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0076 0.0075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0096 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Echinococcus multilocularis FTZ F1 alpha 0.0123 0.0192 0.0191
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0411 0.077 0.2551
Schistosoma mansoni hypothetical protein 0.1081 0.2118 0.7026
Mycobacterium tuberculosis Probable reductase 0.0678 0.1308 0.1962
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.0077
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0046 0.0037 0.0147
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0123 0.0192 0.063
Brugia malayi Nuclear hormone receptor E75 0.0058 0.0061 0.0197
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0103 0.0151 0.2772
Mycobacterium ulcerans lipase LipD 0.0523 0.0996 0.8048
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1527 0.3014 0.8755
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0076 0.0311
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0123 0.0192 0.0191
Leishmania major cathepsin L-like protease 0.007 0.0085 0.0346
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0098 0.0142 0.0469
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0019 0.0018
Echinococcus multilocularis jumonji domain containing protein 0.0123 0.0192 0.0191
Schistosoma mansoni hypothetical protein 0.0952 0.1859 0.6167
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0045 0.0034 0.0114
Schistosoma mansoni retinoic acid receptor RXR 0.0123 0.0192 0.0636
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0032 0.0102
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0032 0.0125
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0108 0.0161 0.0535
Echinococcus multilocularis SAM and MBT domain containing protein 0.0152 0.025 0.0249
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0045 0.0034 0.0097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0122 0.0189 0.0626
Brugia malayi Bromodomain containing protein 0.0102 0.0148 0.0487
Echinococcus granulosus tumor protein p63 0.1011 0.1977 0.6557
Trypanosoma cruzi importin beta-1 subunit, putative 0.0072 0.009 0.0367
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0019 0.0074
Trypanosoma brucei DNA polymerase eta, putative 0.0063 0.007 0.0285
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0229 0.0755
Echinococcus multilocularis cpg binding protein 0.0135 0.0216 0.0215
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0754 0.146 0.2191
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0229 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0045 0.0034 0.0114
Mycobacterium tuberculosis Probable oxidoreductase 0.0754 0.146 0.2191
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0173 0.0293 0.0966
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0045 0.0034 0.0114
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0059 0.0062 0.0206
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0145 0.0237 0.0236
Schistosoma mansoni Smad4 0.0059 0.0062 0.0206
Brugia malayi orphan nuclear receptor NR2E1 0.0058 0.0061 0.0197
Loa Loa (eye worm) RNA binding protein 0.0063 0.0071 0.0237
Onchocerca volvulus 0.0221 0.0389 0.1042
Echinococcus granulosus Smad4 0.0059 0.0062 0.0203
Trichomonas vaginalis importin beta-1, putative 0.0072 0.009 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.0096 0.5395
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0019 0.0058
Brugia malayi hypothetical protein 0.0069 0.0083 0.0269
Echinococcus granulosus polycomb protein SCMH1 0.0152 0.025 0.0828
Brugia malayi nuclear hormone receptor 0.0058 0.0061 0.0197
Schistosoma mansoni nuclear hormone receptor 0.0123 0.0192 0.0636
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0523 0.0996 0.1493
Onchocerca volvulus 0.0097 0.0139 0.0309
Schistosoma mansoni hypothetical protein 0.0281 0.051 0.1691
Schistosoma mansoni GTP-binding protein alpha subunit 0.0045 0.0034 0.0114
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0678 0.1308 0.1962
Schistosoma mansoni hypothetical protein 0.0411 0.077 0.2554
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0096 0.0953
Schistosoma mansoni hypothetical protein 0.0411 0.077 0.2554
Schistosoma mansoni nuclear receptor 0.0058 0.0061 0.0202
Loa Loa (eye worm) MH2 domain-containing protein 0.0059 0.0062 0.0206
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0045 0.0034 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0019 0.0053
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1298 0.2553 0.8469
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0237
Schistosoma mansoni transcription factor LCR-F1 0.023 0.0407 0.135
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0019 0.006
Mycobacterium ulcerans beta-lactamase 0.0523 0.0996 0.8048
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0055 0.0221
Onchocerca volvulus Protein ultraspiracle homolog 0.0123 0.0192 0.0462
Mycobacterium tuberculosis Conserved protein 0.0523 0.0996 0.1493
Brugia malayi hypothetical protein 0.0065 0.0075 0.0243
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Schistosoma mansoni jumonji/arid domain-containing protein 0.0122 0.0189 0.0626
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0096 0.0278
Loa Loa (eye worm) hypothetical protein 0.0089 0.0124 0.041
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0046 0.0037 0.0117
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0143 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0103 0.0151 0.0625
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0046 0.0037 0.0147
Mycobacterium tuberculosis Probable lipase LipE 0.0523 0.0996 0.1493
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0002 0.0007
Onchocerca volvulus 0.0085 0.0116 0.0238
Trypanosoma cruzi C-8 sterol isomerase, putative 0.109 0.2135 0.8902
Trichomonas vaginalis glutaminase, putative 0.0566 0.1082 0.3145
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0045 0.0034 0.0114
Loa Loa (eye worm) hypothetical protein 0.0371 0.069 0.229
Loa Loa (eye worm) hypothetical protein 0.0173 0.0293 0.0971
Echinococcus granulosus snurportin 1 0.0952 0.1859 0.6166
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0103 0.0151 0.1217
Echinococcus granulosus tar DNA binding protein 0.0063 0.0071 0.0234
Treponema pallidum sodium- and chloride- dependent transporter 0.0148 0.0241 1
Leishmania major DNA polymerase eta, putative 0.0063 0.007 0.0285
Brugia malayi serine/threonine-protein kinase plk-2 0.0108 0.0161 0.0529
Entamoeba histolytica Ran family GTPase 0.0066 0.0076 0.1473
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0045 0.0034 0.0111
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0021 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0221 0.0389 0.1291
Brugia malayi beta-lactamase family protein 0.0523 0.0996 0.3299
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Brugia malayi ecdysteroid receptor 0.0123 0.0192 0.063
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0046 0.0037 0.0355
Trichomonas vaginalis set domain proteins, putative 0.1738 0.3438 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0107 0.0159 0.0158
Schistosoma mansoni sodium/chloride dependent transporter 0.0148 0.0241 0.08
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0103 0.0151 0.8506
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0122 0.1211
Loa Loa (eye worm) hypothetical protein 0.0996 0.1947 0.6458
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0035 0.0034
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0022 0.0148
Schistosoma mansoni hypothetical protein 0.0088 0.0122 0.0405
Trichomonas vaginalis penicillin-binding protein, putative 0.0523 0.0996 0.2894
Leishmania major importin beta-1 subunit, putative 0.0072 0.009 0.0367
Echinococcus granulosus serotonin transporter 0.0148 0.0241 0.0797
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0085 0.0346
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0061 0.006
Brugia malayi MH1 domain containing protein 0.0059 0.0062 0.02
Mycobacterium leprae Probable lipase LipE 0.0523 0.0996 0.6817
Loa Loa (eye worm) MBCTL1 0.0173 0.0293 0.0971
Loa Loa (eye worm) glutathione reductase 0.0297 0.0542 0.1798
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0046 0.0037 0.0119
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0103 0.0151 0.1507
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0116 0.0378
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0046 0.0037 0.0117
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0002 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.0186 0.1854
Echinococcus granulosus cpg binding protein 0.0135 0.0216 0.0713
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0043 0.0031 0.003
Plasmodium vivax hypothetical protein, conserved 0.0523 0.0996 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.0282 0.093
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.003 0.0098
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0021 0.0065
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0152 0.025 0.0635
Toxoplasma gondii HEAT repeat-containing protein 0.0089 0.0124 0.1227
Loa Loa (eye worm) hypothetical protein 0.0432 0.0813 0.2695
Giardia lamblia PHD finger protein 15 0.0088 0.0122 0.6463
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0079 0.0261
Echinococcus multilocularis thioredoxin glutathione reductase 0.0299 0.0546 0.0545
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0045 0.0034 0.0111
Brugia malayi Augmenter of liver regeneration 0.0037 0.0019 0.0059
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0019 0.0074
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0116 0.0115
Onchocerca volvulus 0.0123 0.0192 0.0462
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0108 0.0161 0.016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0116 0.0178 0.0735
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0103 0.0151 0.2772
Entamoeba histolytica G protein alpha subunit, putative 0.0045 0.0034 0.0393
Toxoplasma gondii exonuclease III APE 0.0116 0.0178 0.1773
Leishmania major cathepsin L-like protease 0.007 0.0085 0.0346
Onchocerca volvulus 0.0523 0.0996 0.2824
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Entamoeba histolytica serine/threonine protein kinase, putative 0.0108 0.0161 0.366
Echinococcus multilocularis peregrin 0.0102 0.0148 0.0147
Brugia malayi MH1 domain containing protein 0.0059 0.0062 0.02
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0123 0.0192 0.0632
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0116 0.038
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0045 0.0034 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0116 0.0178 0.326
Loa Loa (eye worm) latrophilin receptor protein 2 0.0411 0.077 0.2553
Brugia malayi jmjC domain containing protein 0.029 0.0526 0.1742
Schistosoma mansoni ap endonuclease 0.0116 0.0178 0.059
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.002 0.0066
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.0282 0.0935
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0578 0.1106 0.4607
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0103 0.0151 0.0625
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.0282 0.0932
Onchocerca volvulus 0.0058 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0887 0.1728 0.5731
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.002 0.0055
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0411 0.077 0.2549
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.004 0.0039
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0002 0.0001
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0152 0.025 0.0831
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0123 0.0192 0.0636
Echinococcus granulosus jumonji domain containing protein 0.0123 0.0192 0.0633
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0123 0.0192 0.0636
Onchocerca volvulus Huntingtin homolog 0.0247 0.0441 0.1195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0032 0.0031
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.002 0.0019
Echinococcus granulosus expressed protein 0.0045 0.0034 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0123 0.0192 0.063
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.0186 0.0278
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Brugia malayi nuclear receptor NHR-67 0.0058 0.0061 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Loa Loa (eye worm) norepinephrine transporter 0.0148 0.0241 0.08
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0045 0.0034 0.0109
Echinococcus multilocularis ecdysone induced protein 78C 0.0123 0.0192 0.0191
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0411 0.077 0.0769
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0226 0.0746
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0116 0.0178 0.0515
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0045 0.0034 0.0109
Schistosoma mansoni zinc finger protein 0.009 0.0124 0.0413
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1044 0.2043 0.6777
Schistosoma mansoni hypothetical protein 0.0048 0.004 0.0134
Schistosoma mansoni hypothetical protein 0.0949 0.1853 0.6147
Echinococcus granulosus neuropeptide s receptor 0.0476 0.0901 0.2988
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0002 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0058 0.0061 0.006
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0019 0.0064
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0019 0.0176
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0046 0.0037 0.0122
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0103 0.0151 0.8506
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0058 0.0061 0.006
Entamoeba histolytica hypothetical protein 0.0072 0.009 0.1819
Echinococcus multilocularis expressed protein 0.0045 0.0034 0.0033
Brugia malayi hypothetical protein 0.0058 0.0061 0.0197
Brugia malayi nuclear receptor NHR-88 0.0058 0.0061 0.0197
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0046 0.0037 0.0147
Echinococcus multilocularis Smad4 0.0059 0.0062 0.0061
Loa Loa (eye worm) acetyltransferase 0.0154 0.0253 0.0839
Schistosoma mansoni hypothetical protein 0.1081 0.2118 0.7026
Loa Loa (eye worm) hypothetical protein 0.0085 0.0116 0.0383
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0114
Leishmania major trypanothione reductase 0.0297 0.0542 0.2255
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0098 0.0142 0.0141
Leishmania major cathepsin L-like protease 0.007 0.0085 0.0346
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0116 0.0178 0.1773
Loa Loa (eye worm) hypothetical protein 0.1298 0.2553 0.8469
Echinococcus multilocularis tumor protein p63 0.1011 0.1977 0.1976
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Trichomonas vaginalis D-aminoacylase, putative 0.0523 0.0996 0.2894
Schistosoma mansoni DNA polymerase eta 0.0063 0.007 0.0232
Echinococcus granulosus beta LACTamase domain containing family member 0.0523 0.0996 0.3301
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0019 0.0073
Brugia malayi hypothetical protein 0.0098 0.0142 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Plasmodium vivax thioredoxin reductase, putative 0.0297 0.0542 0.5437
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0045 0.0034 0.0033
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0083 0.0111 0.0369
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0116 0.0178 0.059
Toxoplasma gondii histone lysine methyltransferase SET1 0.0249 0.0446 0.4468
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0046 0.0037 0.0652
Toxoplasma gondii NADPH-glutathione reductase 0.0103 0.0151 0.1507
Onchocerca volvulus Huntingtin homolog 0.0247 0.0441 0.1195
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.0186 0.0185
Schistosoma mansoni ferritin 0.0028 0.0001 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0103 0.0151 0.0625
Brugia malayi glutaminase DH11.1 0.0566 0.1082 0.3586
Trichomonas vaginalis ran, putative 0.0066 0.0076 0.0219
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Echinococcus granulosus lysine specific demethylase 5A 0.0122 0.0189 0.0623
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0019 0.0073
Onchocerca volvulus 0.0058 0.0061 0.0078
Mycobacterium leprae conserved hypothetical protein 0.0523 0.0996 0.6817
Brugia malayi Fli-1 protein 0.0252 0.0451 0.1493
Leishmania major mitochondrial DNA polymerase beta 0.1221 0.2398 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1221 0.2398 1
Onchocerca volvulus 0.0432 0.0813 0.2286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0045 0.0034 0.0097
Schistosoma mansoni hypothetical protein 0.0411 0.077 0.2554
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0103 0.0151 0.0625
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0253 0.084
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0281 0.051 0.1688
Loa Loa (eye worm) thioredoxin reductase 0.0297 0.0542 0.1798
Schistosoma mansoni smad1 5 8 and 0.0059 0.0062 0.0206
Loa Loa (eye worm) hypothetical protein 0.0042 0.003 0.0098
Onchocerca volvulus 0.0148 0.0242 0.0609
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0754 0.146 0.2191
Plasmodium falciparum importin beta, putative 0.0089 0.0124 0.2257
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0123 0.0192 0.063
Trichomonas vaginalis glutathione reductase, putative 0.0103 0.0151 0.0438
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0706 0.1363 0.4522
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0281 0.051 0.0509
Mycobacterium tuberculosis Conserved protein 0.0523 0.0996 0.1493
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0076 0.0751
Schistosoma mansoni hypothetical protein 0.0041 0.0027 0.0088
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0103 0.0151 0.0226
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0058 0.0061 0.0197
Trypanosoma brucei glucosidase, putative 0.0037 0.0019 0.0073
Onchocerca volvulus Bile acid receptor homolog 0.0123 0.0192 0.0462
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0523 0.0996 0.3303
Brugia malayi mbt repeat family protein 0.0152 0.025 0.0826
Schistosoma mansoni hypothetical protein 0.0887 0.1728 0.5732
Schistosoma mansoni cpg binding protein 0.0135 0.0216 0.0716
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0019 0.0053
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0116 0.0178 0.0266
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0123 0.0192 0.0462
Loa Loa (eye worm) hypothetical protein 0.0148 0.0241 0.08
Brugia malayi Ets-domain containing protein 0.0083 0.0111 0.0364
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1527 0.3014 0.9999
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0103 0.0151 0.0625
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0103 0.0151 0.0625
Trichomonas vaginalis ap endonuclease, putative 0.0116 0.0178 0.0515
Plasmodium falciparum glutathione reductase 0.0297 0.0542 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0289 0.12
Echinococcus granulosus TGF beta signal transducer SmadC 0.0059 0.0062 0.0203
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.0282 0.0281
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0045 0.0034 0.0114
Echinococcus multilocularis neuropeptide s receptor 0.0476 0.0901 0.09
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0123 0.0192 0.0636
Schistosoma mansoni alpha glucosidase 0.0037 0.0019 0.0064
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0143 0.0472
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Echinococcus multilocularis protein patched 0.0042 0.003 0.0029
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0123 0.0192 0.0636
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0209 0.0365 0.1515
Trichomonas vaginalis D-aminoacylase, putative 0.0523 0.0996 0.2894
Schistosoma mansoni lozenge 0.0054 0.0053 0.0177
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0187 0.0619
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0123 0.0192 0.063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.0077
Schistosoma mansoni inositol monophosphatase 0.0076 0.0096 0.032
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0578 0.1106 0.4607
Plasmodium vivax importin-beta 2, putative 0.0089 0.0124 0.1227
Loa Loa (eye worm) hypothetical protein 0.0155 0.0256 0.0851
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0523 0.0996 0.8048
Schistosoma mansoni cpg binding protein 0.0135 0.0216 0.0716
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0045 0.0034 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0071 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0161 0.0466
Echinococcus granulosus expressed conserved protein 0.0093 0.0131 0.0432
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0002 0.0007
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0045 0.0034 0.0097
Schistosoma mansoni ferritin 0.0028 0.0001 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0523 0.0996 0.4148
Loa Loa (eye worm) hypothetical protein 0.0107 0.0159 0.0526
Loa Loa (eye worm) inositol-1 0.0076 0.0096 0.032
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0159 0.0655
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0116 0.0178 0.0735
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0045 0.0034 0.0114
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.002 0.0077
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0076 0.025
Loa Loa (eye worm) G protein alpha subunit 3 0.0045 0.0034 0.0114
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0237
Schistosoma mansoni myelin transcription factor 1 myt1 0.0173 0.0293 0.0972
Loa Loa (eye worm) hypothetical protein 0.029 0.0528 0.1751
Trypanosoma brucei polo-like protein kinase 0.0108 0.0161 0.0665
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0146 0.0485
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0058 0.0061 0.006
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0072 0.0295
Trypanosoma brucei trypanothione reductase 0.0297 0.0542 0.2255
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.002 0.0154
Trypanosoma brucei ISWI complex protein 0.0062 0.0069 0.028
Brugia malayi RNA, U transporter 1 0.0254 0.0454 0.1502
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0123 0.0192 0.0632
Trichomonas vaginalis penicillin-binding protein, putative 0.0523 0.0996 0.2894
Loa Loa (eye worm) hypothetical protein 0.0065 0.0075 0.0249
Brugia malayi MH1 domain containing protein 0.0032 0.0009 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.029 0.0528 0.0527
Mycobacterium ulcerans esterase/lipase LipP 0.0523 0.0996 0.8048
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0069 0.0083 0.0082
Schistosoma mansoni ferritin light chain 0.0028 0.0001 0.0003
Brugia malayi nuclear hormone receptor family member nhr-6 0.0058 0.0061 0.0197
Echinococcus granulosus methyl CpG binding domain protein 2 0.0069 0.0083 0.0272
Schistosoma mansoni ferritin 0.0028 0.0001 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0678 0.1308 0.1962
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.0282 0.0281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0123 0.0192 0.0636
Mycobacterium tuberculosis Probable esterase LipL 0.0523 0.0996 0.1493
Onchocerca volvulus 0.0152 0.025 0.0635
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0103 0.0151 0.1217
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0159 0.0655
Brugia malayi PHD-finger family protein 0.0088 0.0122 0.04
Loa Loa (eye worm) hypothetical protein 0.0071 0.0087 0.0289
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0123 0.0192 0.0632
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0019 0.0064
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0076 0.0096 0.0315
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0122 0.1211
Brugia malayi hypothetical protein 0.0058 0.0061 0.0197
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0624 0.1198 0.3972
Trypanosoma brucei unspecified product 0.0038 0.002 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0019 0.0053
Mycobacterium ulcerans hypothetical protein 0.0643 0.1237 1
Toxoplasma gondii thioredoxin reductase 0.0297 0.0542 0.5437
Leishmania major DNA polymerase eta, putative 0.0037 0.0018 0.0067
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0523 0.0996 0.3303
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0076 0.3565
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0186 0.1497
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0221 0.0389 0.0388
Echinococcus granulosus dnaJ subfamily B 0.0442 0.0832 0.2758
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Echinococcus multilocularis snurportin 1 0.0952 0.1859 0.1858
Mycobacterium tuberculosis Probable hydrolase 0.0523 0.0996 0.1493
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0035 0.0114
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0253 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Echinococcus multilocularis zinc finger protein 0.009 0.0124 0.0123
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0045 0.0034 0.0111
Schistosoma mansoni RAR-like nuclear receptor 0.0123 0.0192 0.0636
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0045 0.0034 0.0109
Onchocerca volvulus 0.0523 0.0996 0.2824
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0237
Loa Loa (eye worm) beta-lactamase 0.0523 0.0996 0.3303
Brugia malayi nuclear hormone receptor family member odr-7 0.0058 0.0061 0.0197
Brugia malayi MH2 domain containing protein 0.0059 0.0062 0.02
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0076 0.0751
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0032 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0123 0.0192 0.0636
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.004 0.0131
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0045 0.0034 0.0109
Brugia malayi MH1 domain containing protein 0.0032 0.0009 0.0026
Mycobacterium ulcerans hypothetical protein 0.0523 0.0996 0.8048
Schistosoma mansoni alpha-glucosidase 0.0144 0.0235 0.0779
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0075 0.0243
Treponema pallidum NADH oxidase 0.0103 0.0151 0.6266
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0678 0.1308 0.1962
Schistosoma mansoni nuclear receptor 0.0058 0.0061 0.0202
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1044 0.2043 0.6776
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0116 0.0178 0.0587
Echinococcus granulosus GPCR family 2 0.0411 0.077 0.2551
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0075 0.0243
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0046 0.0037 0.0355
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0221 0.0389 0.3899
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.002 0.0063
Schistosoma mansoni sex comb on midleg homolog 0.0152 0.025 0.0831
Brugia malayi CXXC zinc finger family protein 0.012 0.0187 0.0614
Schistosoma mansoni gabp alpha 0.0083 0.0111 0.0369
Loa Loa (eye worm) serotonin transporter b 0.0148 0.0241 0.08
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0002 0.0006
Leishmania major DNA polymerase kappa, putative 0.0038 0.002 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Schistosoma mansoni survival motor neuron protein 0.0203 0.0353 0.117
Trichomonas vaginalis D-aminoacylase, putative 0.0523 0.0996 0.2894
Echinococcus multilocularis smad 0.0059 0.0062 0.0061
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0008
Plasmodium vivax glutathione reductase, putative 0.0297 0.0542 0.5437
Brugia malayi Ets-domain containing protein 0.0083 0.0111 0.0364
Trypanosoma cruzi ISWI complex protein 0.0062 0.0069 0.028
Trypanosoma cruzi DNA polymerase eta, putative 0.0063 0.007 0.0285
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0103 0.0151 0.0497
Loa Loa (eye worm) nuclear hormone receptor 0.0058 0.0061 0.0202
Loa Loa (eye worm) hypothetical protein 0.0065 0.0075 0.0249
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0123 0.0192 0.0191
Brugia malayi nuclear hormone receptor 0.0123 0.0192 0.063
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0058 0.0061 0.0199
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0116 0.0178 0.4091
Brugia malayi MH2 domain containing protein 0.0059 0.0062 0.02
Mycobacterium tuberculosis Possible penicillin-binding protein 0.3341 0.6661 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0116 0.0383
Mycobacterium ulcerans glutaminase 0.0566 0.1082 0.8747
Echinococcus granulosus histone acetyltransferase KAT2B 0.0052 0.0049 0.0158
Leishmania major hypothetical protein, conserved 0.0107 0.0159 0.0655
Echinococcus multilocularis polycomb protein SCMH1 0.0152 0.025 0.0249
Echinococcus granulosus histone acetyltransferase MYST2 0.0173 0.0293 0.0969
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.0432 0.0813 0.2695
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.029 0.0526 0.1744
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0145 0.0237 0.0782
Brugia malayi Nuclear hormone receptor E75 0.0058 0.0061 0.0197
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0045 0.0034 0.0114
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0032 0.0031
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0578 0.1106 0.4607
Brugia malayi Inositol-1 0.0076 0.0096 0.0315
Entamoeba histolytica hypothetical protein 0.023 0.0407 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0152 0.025 0.0828
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0096 0.0395
Loa Loa (eye worm) hypothetical protein 0.0286 0.052 0.1724
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0264 0.0474 0.1573
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.002 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.003 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Brugia malayi hypothetical protein 0.0065 0.0075 0.0243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0123 0.0192 0.0636
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0085 0.0346
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0123 0.0192 0.0191
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.0186 0.0614
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0114
Brugia malayi hypothetical protein 0.0107 0.0159 0.0521
Brugia malayi hypothetical protein 0.023 0.0407 0.1345
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0045 0.0034 0.0033
Schistosoma mansoni methyl-cpg binding protein mbd 0.0069 0.0083 0.0275
Echinococcus multilocularis Protein lozenge 0.0054 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0168 0.0283 0.0938
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0045 0.0034 0.0097
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0019 0.0178
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0018 0.0067
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0045 0.0034 0.0033
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0523 0.0996 0.1493
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0061 0.0202
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.008 0.0545
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0172 0.0289 0.12
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0045 0.0034 0.0109
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0065 0.0075 0.0249
Leishmania major C-8 sterol isomerase-like protein 0.109 0.2135 0.8902
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0186 0.0617
Schistosoma mansoni eyes absent homolog 0.0098 0.0142 0.0472
Schistosoma mansoni zinc finger protein 0.0058 0.0061 0.0202
Treponema pallidum exodeoxyribonuclease (exoA) 0.0116 0.0178 0.7366
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0116 0.0178 0.0735
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0371 0.069 0.1927
Echinococcus multilocularis serotonin transporter 0.0148 0.0241 0.024
Onchocerca volvulus Alhambra homolog 0.0088 0.0122 0.0257
Echinococcus granulosus importin subunit beta 1 0.0089 0.0124 0.0407
Echinococcus multilocularis vesicular acetylcholine transporter 0.1527 0.3014 0.3014
Brugia malayi Nuclear hormone receptor-like 1 0.0123 0.0192 0.063
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0096 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0123 0.0192 0.063
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.1044 0.2043 0.6776
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0019 0.0053
Brugia malayi MH2 domain containing protein 0.086 0.1672 0.5545
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0019 0.0073
Brugia malayi F/Y-rich N-terminus family protein 0.0081 0.0108 0.0353
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0148 0.0241 0.0795
Echinococcus multilocularis expressed conserved protein 0.0093 0.0131 0.013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0123 0.0192 0.063
Schistosoma mansoni ets-related 0.0252 0.0451 0.1497
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0088 0.0122 0.0405
Brugia malayi Pre-SET motif family protein 0.1527 0.3015 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0103 0.0151 0.0625
Entamoeba histolytica hypothetical protein 0.023 0.0407 1
Schistosoma mansoni vesicular acetylcholine transporter 0.1527 0.3014 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0116 0.0178 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0123 0.0192 0.0632
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1044 0.2043 0.6776
Schistosoma mansoni patched 1 0.0042 0.003 0.0098
Loa Loa (eye worm) mbt repeat family protein 0.0152 0.025 0.0831
Loa Loa (eye worm) hypothetical protein 0.0123 0.0192 0.0636
Loa Loa (eye worm) hypothetical protein 0.0247 0.0441 0.1463
Loa Loa (eye worm) hypothetical protein 0.0148 0.0241 0.08
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0624 0.1198 0.1197
Onchocerca volvulus 0.0203 0.0353 0.0935
Brugia malayi hypothetical protein 0.0432 0.0813 0.2691
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0045 0.0034 0.0114
Brugia malayi vesicular acetylcholine transporter unc-17 0.1527 0.3014 0.9999
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0058 0.0061 0.0202
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0065 0.0075 0.0249
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0071 0.0237
Brugia malayi Latrophilin receptor protein 2 0.0411 0.077 0.2549
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1044 0.2043 0.6777
Schistosoma mansoni hypothetical protein 0.0203 0.0353 0.117
Brugia malayi tailless protein 0.0058 0.0061 0.0197
Loa Loa (eye worm) hypothetical protein 0.0152 0.025 0.0831
Brugia malayi Bromodomain containing protein 0.0159 0.0263 0.0867
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.0161 0.0665
Loa Loa (eye worm) runx1 0.0054 0.0053 0.0177
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0077
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0059 0.0062 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.0089 0.0124 0.0509
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0076 0.0311
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0019 0.0328
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0002 0.0003
Schistosoma mansoni apoferritin-2 0.0028 0.0001 0.0003
Brugia malayi nuclear receptor RXR 0.0058 0.0061 0.0197
Echinococcus multilocularis mothers against decapentaplegic 5 0.0059 0.0062 0.0061
Echinococcus multilocularis dnaJ subfamily B 0.0442 0.0832 0.0831
Leishmania major GTP-binding protein, putative 0.0066 0.0076 0.0311
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0002 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0299 0.0546 0.181
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0754 0.146 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0116 0.0178 0.0735
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1044 0.2043 0.2042
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0678 0.1308 0.8957
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0161 0.0535
Loa Loa (eye worm) hypothetical protein 0.0065 0.0075 0.0249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0065 0.0075 0.0249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0297 0.0542 0.0812
Schistosoma mansoni hypothetical protein 0.0084 0.0112 0.0372
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0019 0.0053
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0103 0.0151 0.1507
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0032 0.0089
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0019 0.0074
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0058 0.0061 0.0078
Plasmodium vivax ataxin-2 like protein, putative 0.0107 0.0159 0.1579
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0006
Schistosoma mansoni smad1 5 8 and 0.0059 0.0062 0.0206
Schistosoma mansoni zinc finger protein 0.0062 0.0069 0.0228
Schistosoma mansoni hypothetical protein 0.023 0.0407 0.135
Brugia malayi Calcitonin receptor-like protein seb-1 0.1298 0.2553 0.8469
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0098 0.0142 0.0472
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Brugia malayi Smad1 0.0059 0.0062 0.02
Leishmania major hypothetical protein, conserved 0.0037 0.0019 0.0074
Echinococcus granulosus dna polymerase eta 0.0063 0.007 0.0229
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0019 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.029 0.0528 0.1752
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0411 0.077 0.0769
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0032 0.01
Schistosoma mansoni nuclear receptor nhr-48 0.0058 0.0061 0.0202
Giardia lamblia NADH oxidase lateral transfer candidate 0.0103 0.0151 0.8326
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0523 0.0996 0.3299
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0002 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0186 0.0617
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0045 0.0034 0.0109
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0019 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0077
Giardia lamblia Kinase, PLK 0.0108 0.0161 0.894
Schistosoma mansoni ferritin light chain 0.0028 0.0001 0.0003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.0096 0.0772
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0114
Echinococcus multilocularis nuclear receptor nhr 48 0.0058 0.0061 0.006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0065 0.0075 0.0245
Echinococcus granulosus thyroid hormone receptor alpha 0.0058 0.0061 0.0199
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0123 0.0192 0.0636
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0148 0.0241 0.08
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Schistosoma mansoni kinase 0.0055 0.0054 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0123 0.0192 0.063
Echinococcus multilocularis protein dispatched 1 0.0048 0.0042 0.0041
Mycobacterium tuberculosis Conserved protein 0.0523 0.0996 0.1493
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0159 0.2905
Loa Loa (eye worm) hypothetical protein 0.0523 0.0996 0.3303
Echinococcus granulosus peregrin 0.0102 0.0148 0.0489
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0116 0.0178 0.1431
Onchocerca volvulus 0.0148 0.0241 0.0607
Echinococcus granulosus Nuclear hormone receptor HR96 0.0058 0.0061 0.0199
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0045 0.0034 0.0097
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0032 0.074
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0052 0.0049 0.0473
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0103 0.0151 0.5
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0143 0.3198
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0002 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0019 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0123 0.0192 0.063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.1044 0.2043 0.6774
Schistosoma mansoni hypothetical protein 0.0041 0.0027 0.0088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0032 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0523 0.0996 0.4148
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0108 0.0161 0.0665
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.009 0.0258
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0032 0.0125
Toxoplasma gondii LsmAD domain-containing protein 0.0107 0.0159 0.1579
Schistosoma mansoni hypothetical protein 0.0041 0.0027 0.0088
Brugia malayi Pre-SET motif family protein 0.0221 0.0389 0.1286
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0085 0.0346
Echinococcus granulosus geminin 0.1081 0.2118 0.7025
Loa Loa (eye worm) transcription factor SMAD2 0.086 0.1672 0.5548
Echinococcus multilocularis importin subunit beta 1 0.0089 0.0124 0.0123
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0103 0.0151 0.0625
Echinococcus multilocularis beta LACTamase domain containing family member 0.0523 0.0996 0.0995
Plasmodium falciparum phd finger protein, putative 0.0088 0.0122 0.2227
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.023 0.0407 0.0406
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0202
Loa Loa (eye worm) hypothetical protein 0.0099 0.0143 0.0475
Echinococcus multilocularis thyroid hormone receptor alpha 0.0404 0.0757 0.0756
Loa Loa (eye worm) bromodomain containing protein 0.0075 0.0095 0.0316
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.0186 0.0769
Echinococcus granulosus vesicular acetylcholine transporter 0.1527 0.3014 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0018 0.0162

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.698 Inhibition of Influenza virus neuraminidase A ChEMBL. No reference
IC50 (binding) = 2 nM Inhibitory activity against influenza A neuraminidase from influenza A/PR/8/34 (H1N1). ChEMBL. 9651151
IC50 (binding) = 2 nM Inhibitory activity against influenza A neuraminidase from influenza A/PR/8/34 (H1N1). ChEMBL. 9651151
IC50 (binding) = 2 uM Inhibition of Influenza virus neuraminidase A ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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