Detailed information for compound 1334869

Basic information

Technical information
  • TDR Targets ID: 1334869
  • Name: 4-(1H-benzimidazol-2-yl)-1-(phenylmethyl)pyrr olidin-2-one
  • MW: 291.347 | Formula: C18H17N3O
  • H donors: 1 H acceptors: 2 LogP: 2.27 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC(CN1Cc1ccccc1)c1nc2c([nH]1)cccc2
  • InChi: 1S/C18H17N3O/c22-17-10-14(12-21(17)11-13-6-2-1-3-7-13)18-19-15-8-4-5-9-16(15)20-18/h1-9,14H,10-12H2,(H,19,20)
  • InChiKey: ZVMRDVATVAPMCL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(1H-benzimidazol-2-yl)-1-(phenylmethyl)-2-pyrrolidinone
  • 4-(1H-benzimidazol-2-yl)-1-(benzyl)-2-pyrrolidone
  • IDI1_009569
  • ST5145642
  • MLS000102598
  • SMR000017769
  • IFLab1_003110

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Homo sapiens karyopherin (importin) beta 1 No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Immunoglobulin 0.0663 0.0467 0.0461
Trypanosoma cruzi casein kinase, delta isoform, putative 0.065 0.0452 0.0466
Plasmodium falciparum protein kinase, putative 0.0451 0.023 0.2018
Onchocerca volvulus 0.0351 0.0118 0.0114
Toxoplasma gondii AGC kinase 0.0852 0.0678 0.6312
Echinococcus granulosus NDR protein kinase 0.0587 0.0382 0.0374
Echinococcus multilocularis serine:threonine protein kinase 38 0.0587 0.0382 0.0382
Echinococcus multilocularis protein kinase c iota type 0.0847 0.0671 0.0671
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0605 0.0402 0.0402
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Schistosoma mansoni serine/threonine protein kinase 0.1615 0.1529 0.3716
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Giardia lamblia Kinase, STE STE20 0.0402 0.0176 0.1447
Echinococcus granulosus kinase suppressor of Ras 1 0.0265 0.0022 0.0002
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0831 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0702 0.051 0.0506
Trypanosoma cruzi polo-like protein kinase, putative 0.0348 0.0115 0.0119
Schistosoma mansoni vesicular amine transporter 0.0663 0.0467 0.11
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0401 0.0174 0.0179
Schistosoma mansoni protein kinase 0.0686 0.0492 0.1164
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0605 0.0402 0.3663
Loa Loa (eye worm) TK/ALK protein kinase 0.5274 0.5613 0.5769
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Loa Loa (eye worm) hypothetical protein 0.0575 0.0368 0.0359
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0513 0.0299 0.0299
Echinococcus granulosus tyrosine protein kinase Fyn 0.1127 0.0984 0.0995
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Plasmodium falciparum calcium-dependent protein kinase 2 0.0605 0.0402 0.3663
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.055 0.034 0.034
Entamoeba histolytica protein kinase, putative 0.0606 0.0403 0.3218
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0663 0.0467 0.11
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Plasmodium falciparum serine/threonine protein kinase KIN 0.0401 0.0174 0.1483
Loa Loa (eye worm) hypothetical protein 0.0336 0.0101 0.0084
Schistosoma mansoni hypothetical protein 0.0372 0.0141 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0799 0.0618 0.1473
Onchocerca volvulus 0.0464 0.0244 0.0263
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0348 0.0115 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.1124 0.098 0.8076
Echinococcus multilocularis protein kinase shaggy 0.1197 0.1062 0.1062
Echinococcus granulosus hemicentin 1 0.0302 0.0064 0.0045
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0686 0.0492 0.0488
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0522 0.0309 0.0298
Onchocerca volvulus 0.0495 0.0278 0.0303
Echinococcus granulosus N chimaerin 0.0395 0.0167 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Echinococcus granulosus cyclin dependent kinase 0.0522 0.0309 0.0298
Schistosoma mansoni serine/threonine protein kinase 0.1124 0.098 0.2365
Trypanosoma brucei Pseudokinase, putative 0.0265 0.0022 0.0023
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1127 0.0984 0.0995
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1333 0.1214 0.125
Entamoeba histolytica hypothetical protein 0.0268 0.0026 0.0205
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0377 0.0147 0.0132
Schistosoma mansoni growth factor receptor-bound protein 0.0424 0.0199 0.0442
Brugia malayi hypothetical protein 0.0702 0.051 0.0506
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0401 0.0174 0.0179
Brugia malayi Protein kinase c protein 2 0.0398 0.0171 0.0156
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0379 0.015 0.0134
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.895 0.9716 1
Echinococcus multilocularis PAK box P21 Rho binding 0.0378 0.0148 0.0148
Toxoplasma gondii AGC kinase 0.0728 0.0539 0.4979
Echinococcus granulosus insulin receptor 0.1529 0.1434 0.1458
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0395 0.0167 0.0152
Echinococcus granulosus tyrosine protein kinase otk 0.0302 0.0064 0.0045
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Leishmania major protein kinase A catalytic subunit isoform 1 0.0852 0.0678 0.0698
Brugia malayi Tyrosine-protein kinase abl-1 0.1134 0.0992 0.1003
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0401 0.0174 0.0179
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0401 0.0174 0.0179
Loa Loa (eye worm) hypothetical protein 0.0663 0.0467 0.0461
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0678
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Brugia malayi probable protein kinase 0.1699 0.1623 0.1654
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2579 0.2605 0.2605
Loa Loa (eye worm) TK protein kinase 0.061 0.0407 0.0399
Trypanosoma cruzi casein kinase, putative 0.065 0.0452 0.0466
Loa Loa (eye worm) hypothetical protein 0.147 0.1367 0.1389
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Plasmodium falciparum glycogen synthase kinase 3 0.1197 0.1062 1
Brugia malayi casein kinase 1, delta 0.065 0.0452 0.0446
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Onchocerca volvulus 0.0663 0.0467 0.0525
Echinococcus multilocularis cyclin dependent kinase 9 0.0478 0.026 0.026
Plasmodium falciparum NIMA related kinase 1 0.0304 0.0065 0.0438
Echinococcus granulosus protein kinase shaggy 0.1197 0.1062 0.1075
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.0205 0.0457
Schistosoma mansoni serine/threonine protein kinase 0.055 0.034 0.0788
Schistosoma mansoni tyrosine kinase 0.0567 0.0359 0.0836
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1197 0.1062 0.1075
Echinococcus multilocularis protein kinase 0.0265 0.0022 0.0022
Plasmodium falciparum calcium-dependent protein kinase 5 0.0605 0.0402 0.3663
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0304 0.0065 0.0438
Brugia malayi Protein kinase domain containing protein 0.0367 0.0136 0.012
Echinococcus multilocularis dual specificity mitogen activated protein 0.1333 0.1214 0.1214
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0697 0.0505 0.1194
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0307 0.0069 0.0473
Brugia malayi protein-tyrosine kinase 0.095 0.0786 0.0791
Loa Loa (eye worm) SRC-1 0.1127 0.0984 0.0995
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0761 0.0576 0.0574
Schistosoma mansoni hypothetical protein 0.0712 0.0521 0.1235
Trypanosoma brucei casein kinase I, isoform 2 0.065 0.0452 0.0466
Entamoeba histolytica protein kinase, putative 0.0378 0.0148 0.1182
Schistosoma mansoni tyrosine kinase 0.0672 0.0477 0.1125
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis cyclin dependent kinase 9 0.0435 0.0212 0.0212
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0492 0.4056
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1367 0.1253 0.1289
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Entamoeba histolytica hypothetical protein 0.1367 0.1253 1
Leishmania major hypothetical protein, conserved 0.0265 0.0022 0.0023
Echinococcus multilocularis calcium dependent protein kinase 0.0418 0.0194 0.0194
Echinococcus multilocularis tyrosine kinase 0.0265 0.0022 0.0022
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0587 0.0382 0.0374
Schistosoma mansoni protein kinase 0.2579 0.2605 0.6365
Echinococcus granulosus fibroblast growth factor receptor 4 0.148 0.1379 0.1402
Echinococcus granulosus activated cdc42 kinase 1 0.1734 0.1662 0.1694
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0686 0.0492 0.4536
Brugia malayi Tyrosine-protein kinase abl-1 0.1374 0.126 0.1279
Schistosoma mansoni protein kinase 0.0988 0.0829 0.1992
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0831 0.0654 0.0654
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Echinococcus granulosus casein kinase I gamma 0.0391 0.0163 0.0148
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0391 0.0163 0.0353
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0712 0.0521 0.0517
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0327 0.0091 0.0688
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Protein kinase domain containing protein 0.0368 0.0137 0.0121
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0839 0.0663 0.0663
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Echinococcus multilocularis hemicentin 1 0.0302 0.0064 0.0064
Brugia malayi serine/threonine-protein kinase 6 0.0686 0.0492 0.0488
Echinococcus granulosus casein kinase I delta 0.065 0.0452 0.0446
Trichomonas vaginalis CK1 family protein kinase 0.065 0.0452 0.3727
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0441 0.0218 0.0205
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0341 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0522 0.0309 0.0318
Brugia malayi hypothetical protein 0.0612 0.0409 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.0115 0.0236
Entamoeba histolytica casein kinase, putative 0.0263 0.002 0.0157
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus tyrosine protein kinase csk 0.0265 0.0022 0.0002
Trypanosoma brucei protein kinase, putative 0.1197 0.1062 0.1093
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Echinococcus granulosus MAM 0.0343 0.0109 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0206 0.046
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0136 0.1121
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Brugia malayi Protein kinase domain containing protein 0.0335 0.0101 0.0084
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0495 0.0278 0.2223
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.095 0.0786 0.0791
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0852 0.0678 0.6312
Trichomonas vaginalis TK family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0967 0.0805 0.081
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Giardia lamblia Aurora kinase 0.0686 0.0492 0.4056
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Onchocerca volvulus Slit protein homolog 0.0289 0.0049 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Onchocerca volvulus 0.0495 0.0278 0.0303
Schistosoma mansoni cell adhesion molecule 0.08 0.062 0.1477
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi serine/threonine-protein kinase PAK 7 0.2235 0.2221 0.2271
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0852 0.0678 0.0698
Echinococcus granulosus tyrosine kinase 0.095 0.0786 0.0791
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0605 0.0402 0.3663
Brugia malayi Protein kinase domain containing protein 0.0798 0.0617 0.0616
Trichomonas vaginalis STE family protein kinase 0.0402 0.0176 0.1447
Echinococcus granulosus dual specificity 0.0307 0.0069 0.0051
Onchocerca volvulus 0.0939 0.0775 0.0888
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase, putative 0.072 0.053 0.4228
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Schistosoma mansoni serine/threonine protein kinase 0.0597 0.0393 0.0918
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0341 0.0107 0.009
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2044 0.2008 0.2008
Brugia malayi Protein kinase domain containing protein 0.0462 0.0242 0.023
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1615 0.1529 0.1557
Schistosoma mansoni protein kinase 0.2579 0.2605 0.6365
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2317 0.2313 0.2704
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus multilocularis expressed conserved protein 0.0302 0.0063 0.0063
Entamoeba histolytica receptor protein kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus serine:threonine protein kinase 3 0.0441 0.0218 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0138 0.0292
Loa Loa (eye worm) hypothetical protein 0.0965 0.0804 0.0809
Entamoeba histolytica protein kinase domain containing protein 0.0307 0.0069 0.055
Echinococcus multilocularis tyrosine protein kinase csk 0.0265 0.0022 0.0022
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1124 0.098 0.1009
Schistosoma mansoni protein kinase 0.1699 0.1623 0.3948
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1197 0.1062 0.2566
Loa Loa (eye worm) TK/INSR protein kinase 0.1529 0.1434 0.1458
Schistosoma mansoni protein kinase 0.0378 0.0148 0.0316
Giardia lamblia Kinase, NEK 0.0304 0.0065 0.0538
Echinococcus granulosus defective proboscis extension response 0.0663 0.0467 0.0461
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3007 0.3083 0.316
Loa Loa (eye worm) IKK protein kinase 0.7856 0.8494 0.874
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0711 0.052 0.0516
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1124 0.098 0.1009
Brugia malayi Protein kinase domain containing protein 0.1367 0.1253 0.1272
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0451 0.023 0.0217
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1427 0.1319 0.1319
Echinococcus granulosus tyrosine protein kinase Srms 0.0958 0.0796 0.08
Echinococcus multilocularis dual specificity 0.0307 0.0069 0.0069
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0451 0.023 0.023
Onchocerca volvulus Serine\/threonine kinase homolog 0.0348 0.0115 0.011
Brugia malayi Protein kinase domain containing protein 0.0351 0.0118 0.0102
Leishmania major protein kinase, putative 0.0451 0.023 0.0237
Brugia malayi Protein kinase domain containing protein 0.0495 0.0278 0.0267
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0566 0.0358 0.0349
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0839 0.0663 0.0664
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0107 0.009
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1124 0.098 0.1009
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0265 0.0022 0.0022
Schistosoma mansoni ephrin receptor 0.0338 0.0103 0.0206
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.895 0.9716 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0429 0.0205 0.0192
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1367 0.1253 0.1272
Echinococcus granulosus epidermal growth factor receptor 0.0967 0.0806 0.0811
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Giardia lamblia Protein 21.1 0.0265 0.0022 0.0181
Echinococcus multilocularis roundabout 2 0.1004 0.0847 0.0847
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0521 0.0536
Echinococcus granulosus casein kinase I alpha 0.065 0.0452 0.0446
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0527 0.0315 0.0305
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0451 0.023 0.2018
Echinococcus granulosus retinal guanylyl cyclase 2 0.0265 0.0022 0.0002
Brugia malayi Protein kinase domain containing protein 0.0495 0.0278 0.0267
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1333 0.1214 0.1232
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Onchocerca volvulus Serine\/threonine kinase homolog 0.0335 0.0101 0.0093
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1124 0.098 0.1009
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0094 0.0183
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0401 0.0174 0.0159
Loa Loa (eye worm) TK/KIN16 protein kinase 0.368 0.3834 0.3934
Toxoplasma gondii protein kinase 0.0265 0.0022 0.0023
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0967 0.0806 0.0811
Loa Loa (eye worm) TK/DDR protein kinase 0.034 0.0106 0.0089
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0605 0.0402 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0492 0.4056
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0341 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.1197 0.1062 0.8478
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0265 0.0022 0.0002
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0265 0.0022 0.0002
Echinococcus multilocularis dual specificity protein kinase clk2 0.1124 0.098 0.098
Echinococcus multilocularis snurportin 1 0.0372 0.0141 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0063 0.0108
Loa Loa (eye worm) hypothetical protein 0.0761 0.0576 0.0574
Onchocerca volvulus 0.1197 0.1062 0.1228
Loa Loa (eye worm) hypothetical protein 0.0774 0.059 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0285 0.0045 0.0367
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.065 0.0452 0.0446
Echinococcus granulosus neuroglian 0.0867 0.0694 0.0696
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0348 0.0115 0.0115
Brugia malayi Protein kinase domain containing protein 0.0901 0.0732 0.0735
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0265 0.0022 0.0006
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0327 0.0091 0.0091
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0663 0.0467 0.0467
Loa Loa (eye worm) RGC/RGC protein kinase 0.0265 0.0022 0.0002
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.148 0.1379 0.1379
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus tyrosine protein kinase Lyn 0.1313 0.1192 0.1209
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0605 0.0402 0.3663
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis casein kinase I alpha 0.065 0.0452 0.0452
Brugia malayi Serine/threonine-protein kinase SULU 0.2914 0.2979 0.3052
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0416 0.0191 0.1524
Entamoeba histolytica receptor protein kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) protein kinase domain-containing protein 0.0391 0.0163 0.0148
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0663 0.0467 0.11
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0348 0.0115 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.0975 0.2352
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0395 0.0167 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Echinococcus granulosus protein kinase c iota type 0.0847 0.0671 0.0672
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1197 0.1062 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0522 0.0309 0.0318
Entamoeba histolytica protein kinase, putative 0.0307 0.0069 0.055
Brugia malayi Protein kinase domain containing protein 0.0495 0.0278 0.0267
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0712 0.0521 0.1235
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.895 0.9716 1
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1124 0.098 0.9216
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0831 0.0653 0.0654
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1119 0.0975 0.0985
Plasmodium vivax casein kinase 1, putative 0.065 0.0452 0.4152
Schistosoma mansoni tyrosine kinase 0.2277 0.2268 0.5536
Echinococcus granulosus retinal guanylyl cyclase 2 0.0265 0.0022 0.0002
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0435 0.0212 0.0198
Schistosoma mansoni tyrosine protein kinase 0.0265 0.0022 0.0006
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0265 0.0022 0.0002
Giardia lamblia Kinase, CMGC CDK 0.0522 0.0309 0.2545
Brugia malayi serine/threonine kinase 12 0.0686 0.0492 0.0488
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0605 0.0402 0.0402
Onchocerca volvulus Tyrosine kinase homolog 0.3123 0.3212 0.3765
Echinococcus multilocularis cyclin dependent kinase 1 0.0522 0.0309 0.0309
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0605 0.0402 0.0394
Loa Loa (eye worm) hypothetical protein 0.0712 0.0521 0.0517
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0898 0.0729 0.0732
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0789 0.0607 0.0606
Echinococcus granulosus cyclin dependent kinase 19 0.1786 0.1719 0.1753
Trypanosoma cruzi cdc2-related kinase 1 0.0522 0.0309 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.0435 0.0212 0.0473
Brugia malayi Immunoglobulin I-set domain containing protein 0.368 0.3834 0.3934
Echinococcus granulosus cGMP dependent protein kinase 0.0302 0.0063 0.0045
Schistosoma mansoni tyrosine kinase 0.0672 0.0477 0.1125
Schistosoma mansoni vam6/vps39 related 0.0712 0.0521 0.1235
Schistosoma mansoni septate junction protein 0.0302 0.0064 0.0108
Trichomonas vaginalis protein tyrosine kinase, putative 0.0265 0.0022 0.0181
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1119 0.0975 0.0975
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.002 0.0157
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0341 0.0107 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0101 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0379 0.015 0.1195
Brugia malayi intracellular kinase 0.1197 0.1062 0.1075
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.0305 0.0067 0.0049
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0265 0.0022 0.0002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0401 0.0174 0.1391
Echinococcus granulosus serine/threonine protein kinase 0.0373 0.0142 0.0127
Echinococcus multilocularis protein kinase 0.0265 0.0022 0.0022
Echinococcus multilocularis cyclin dependent kinase 5 0.0522 0.0309 0.0309
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0379 0.015 0.0134
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0265 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2438 0.2448 0.2504
Echinococcus granulosus calcium dependent protein kinase 0.0418 0.0194 0.0179
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Brugia malayi cell division control protein 2 homolog 0.0522 0.0309 0.0298
Trypanosoma cruzi casein kinase II, putative 0.0263 0.002 0.002
Trichomonas vaginalis protein kinase atn1, putative 0.0265 0.0022 0.0181
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0265 0.0022 0.0002
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0327 0.0091 0.0688
Loa Loa (eye worm) AUR protein kinase 0.0686 0.0492 0.0488
Echinococcus granulosus cyclin dependent kinase 5 0.0522 0.0309 0.0298
Loa Loa (eye worm) hypothetical protein 0.0663 0.0467 0.0461
Echinococcus multilocularis 0.0988 0.0829 0.0829
Schistosoma mansoni serine/threonine protein kinase 0.3007 0.3083 0.7542
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Schistosoma mansoni tyrosine kinase 0.2101 0.2071 0.505
Echinococcus multilocularis titin 0.0429 0.0205 0.0205
Echinococcus multilocularis serine:threonine protein kinase 0.0367 0.0136 0.0136
Plasmodium falciparum tyrosine kinase-like protein 0.0265 0.0022 0.0023
Loa Loa (eye worm) serine/threonine protein kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.1734 0.1662 0.1694
Onchocerca volvulus 0.0382 0.0153 0.0154
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0522 0.0309 0.0298
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0712 0.0521 0.1235
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0686 0.0492 0.3931
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Echinococcus multilocularis epidermal growth factor receptor 0.1125 0.0982 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.1427 0.1319 0.32
Toxoplasma gondii histone kinase SNF1, putative 0.0401 0.0174 0.1483
Onchocerca volvulus 0.7856 0.8494 1
Schistosoma mansoni tyrosine kinase 0.3902 0.4082 1
Schistosoma mansoni serine/threonine protein kinase 0.0686 0.0492 0.1164
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0313 0.0076 0.0076
Schistosoma mansoni serine/threonine-protein kinase 0.0373 0.0142 0.0302
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0679
Schistosoma mansoni cell adhesion molecule 0.0302 0.0064 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Schistosoma mansoni tyrosine kinase 0.0967 0.0806 0.1937
Entamoeba histolytica protein kinase domain containing protein 0.1367 0.1253 1
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0679
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0492 0.4056
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi casein kinase I 0.065 0.0452 0.0446
Leishmania major protein kinase, putative 0.0686 0.0492 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0174 0.0381
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0982 0.0822 0.0828
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0605 0.0402 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.2914 0.2979 0.7285
Loa Loa (eye worm) RGC/RGC protein kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) TK protein kinase 0.095 0.0786 0.0791
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0666 0.047 0.0464
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1197 0.1062 0.1093
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Trichomonas vaginalis AGC family protein kinase 0.0631 0.043 0.3545
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1472 0.137 0.1392
Giardia lamblia Kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0302 0.0064 0.0064
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0407 0.0181 0.0166
Echinococcus granulosus dual specificity 0.0307 0.0069 0.0051
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0265 0.0022 0.0002
Giardia lamblia Kinase, CMGC DYRK 0.0307 0.0069 0.0568
Brugia malayi integrin-linked kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.1181 0.1045 0.1057
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0281 0.004 0.0021
Trichomonas vaginalis STE family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0265 0.0022 0.0022
Echinococcus granulosus peroxidasin 0.0305 0.0067 0.0049
Plasmodium falciparum protein kinase, putative 0.0265 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0747 0.056 0.0558
Echinococcus multilocularis cyclin dependent kinase 19 0.1786 0.1719 0.1719
Schistosoma mansoni protein kinase 0.0402 0.0176 0.0384
Brugia malayi Guanylyl cyclase protein 23 0.0265 0.0022 0.0002
Brugia malayi Protein kinase domain containing protein 0.7856 0.8494 0.874
Loa Loa (eye worm) hypothetical protein 0.0774 0.059 0.0588
Schistosoma mansoni rap gtpase-activating protein 0.0712 0.0521 0.1235
Entamoeba histolytica protein kinase domain containing protein 0.0435 0.0212 0.1689
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Loa Loa (eye worm) TK/ROR protein kinase 0.0469 0.025 0.0237
Echinococcus multilocularis FL cytokine receptor 0.0265 0.0022 0.0022
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0141 0.0126
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0728 0.0539 0.0535
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0852 0.0678 0.0698
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0521 0.0536
Echinococcus multilocularis raf serine:threonine protein kinase 0.043 0.0206 0.0206
Onchocerca volvulus 0.0495 0.0278 0.0303
Loa Loa (eye worm) hypothetical protein 0.0566 0.0358 0.0349
Loa Loa (eye worm) hypothetical protein 0.0747 0.056 0.0558
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0265 0.0022 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Loa Loa (eye worm) hypothetical protein 0.034 0.0106 0.0089
Loa Loa (eye worm) TK/ACK protein kinase 0.0265 0.0022 0.0002
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0605 0.0402 0.3663
Echinococcus granulosus growth factor receptor bound protein 2 0.0424 0.0199 0.0185
Loa Loa (eye worm) hypothetical protein 0.0341 0.0107 0.009
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1127 0.0984 0.0984
Echinococcus granulosus Vam6:Vps39 protein 0.0712 0.0521 0.0517
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0138 0.0292
Echinococcus multilocularis serine:threonine protein kinase N2 0.1738 0.1666 0.1666
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Onchocerca volvulus 0.0985 0.0826 0.0949
Echinococcus multilocularis casein kinase I delta 0.065 0.0452 0.0452
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Echinococcus multilocularis casein kinase I delta 0.065 0.0452 0.0452
Entamoeba histolytica tyrosin kinase, putative 0.0312 0.0075 0.0598
Brugia malayi SH2 domain containing protein 0.0839 0.0663 0.0664
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1568 0.1477 0.1477
Brugia malayi Temporarily assigned gene name protein 59 0.0712 0.0521 0.0517
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0678
Schistosoma mansoni protein kinase 0.2579 0.2605 0.6365
Entamoeba histolytica protein kinase, putative 0.1367 0.1253 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1127 0.0984 0.0984
Schistosoma mansoni tyrosine kinase 0.0703 0.0511 0.1209
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0712 0.0521 0.0521
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2044 0.2008 0.205
Echinococcus multilocularis insulin receptor 0.1529 0.1434 0.1434
Toxoplasma gondii hypothetical protein 0.0747 0.056 0.5187
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1127 0.0984 0.0984
Echinococcus multilocularis receptor type guanylyl cyclase 0.0265 0.0022 0.0022
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0335 0.0101 0.0101
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.0289 0.0049 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0634 0.0434 0.102
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.1127 0.0984 0.0995
Echinococcus granulosus cGMP dependent protein kinase 1 0.0302 0.0063 0.0045
Echinococcus multilocularis casein kinase ii subunit alpha 0.0263 0.002 0.002
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0379 0.015 0.015
Schistosoma mansoni serine/threonine protein kinase 0.065 0.0452 0.1065
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Echinococcus multilocularis tyrosine kinase 0.0495 0.0278 0.0278
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0277 0.0036 0.0017
Echinococcus granulosus serine threonine protein kinase nrc 0.0327 0.0091 0.0074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Echinococcus granulosus protein kinase C gamma type 0.0634 0.0434 0.0427
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0988 0.0829 0.0834
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0268 0.0026 0.0205
Schistosoma mansoni roundabout 0.0302 0.0064 0.0108
Loa Loa (eye worm) AUR protein kinase 0.0686 0.0492 0.0488
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0852 0.0678 0.0698
Echinococcus granulosus serine:threonine protein kinase 0.0367 0.0136 0.012
Echinococcus granulosus dual specificity 0.0307 0.0069 0.0051
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1154 0.1015 0.1026
Brugia malayi Stress-activated protein kinase jnk-1 0.3007 0.3083 0.316
Schistosoma mansoni ste20-related kinase 0.0382 0.0153 0.0328
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis STE family protein kinase 0.0402 0.0176 0.1447
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Leishmania major protein kinase, putative 0.1124 0.098 0.1009
Entamoeba histolytica protein kinase, putative 0.0774 0.059 0.4708
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1568 0.1477 0.1503
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1124 0.098 0.0991
Echinococcus multilocularis hemicentin 1 0.0302 0.0064 0.0064
Brugia malayi Prion-like- 0.0302 0.0064 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0307 0.0069 0.0071
Echinococcus granulosus titin 0.0429 0.0205 0.0192
Echinococcus granulosus hypothetical protein 0.0937 0.0772 0.0776
Schistosoma mansoni tyrosine kinase 0.1125 0.0982 0.237
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0036 0.5
Echinococcus multilocularis activated cdc42 kinase 1 0.1734 0.1662 0.1662
Entamoeba histolytica protein kinase, putative 0.0268 0.0026 0.0205
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1127 0.0984 0.0984
Echinococcus multilocularis dual specificity 0.0307 0.0069 0.0069
Echinococcus multilocularis heat shock protein 70 0.0265 0.0022 0.0022
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2438 0.2448 0.2448
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.055 0.034 0.034
Echinococcus granulosus receptor type guanylyl cyclase 0.0265 0.0022 0.0002
Echinococcus multilocularis kinase suppressor of Ras 1 0.0265 0.0022 0.0022
Leishmania major casein kinase, putative 0.065 0.0452 0.0466
Loa Loa (eye worm) TK/FER protein kinase 0.0839 0.0663 0.0664
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0307 0.0069 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni cell adhesion molecule 0.0341 0.0107 0.0215
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0302 0.0064 0.0049
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0307 0.0069 0.0071
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1154 0.1015 0.1026
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0903 0.0735 0.0735
Loa Loa (eye worm) TK protein kinase 0.072 0.053 0.0526
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1127 0.0984 0.0984
Brugia malayi Immunoglobulin I-set domain containing protein 0.0429 0.0205 0.0192
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trypanosoma cruzi polo-like protein kinase, putative 0.0348 0.0115 0.0119
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0395 0.0167 0.0364
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0379 0.015 0.0134
Loa Loa (eye worm) RGC/RGC protein kinase 0.0265 0.0022 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.1154 0.1015 0.245
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0281 0.004 0.004
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0265 0.0022 0.0022
Onchocerca volvulus 0.0495 0.0278 0.0303
Echinococcus granulosus snurportin 1 0.0372 0.0141 0.0126
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Schistosoma mansoni protein kinase 0.0368 0.0137 0.0289
Brugia malayi p70 ribosomal S6 kinase beta 0.0728 0.0539 0.0535
Echinococcus granulosus retinal guanylyl cyclase 2 0.0265 0.0022 0.0002
Brugia malayi RhoGAP domain containing protein 0.0395 0.0167 0.0152
Brugia malayi serine/threonine-protein kinase plk-2 0.0348 0.0115 0.0099
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0587 0.0382 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.1786 0.1719 0.4185
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) AGC/PKN protein kinase 0.1738 0.1666 0.1698
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Plasmodium falciparum casein kinase 1 0.065 0.0452 0.4152
Brugia malayi Variant SH3 domain containing protein 0.0277 0.0036 0.0017
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0747 0.056 0.0558
Echinococcus multilocularis Immunoglobulin 0.0663 0.0467 0.0467
Schistosoma mansoni protein kinase 0.1333 0.1214 0.294
Onchocerca volvulus 0.0712 0.0521 0.0589
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0343 0.0109 0.0093
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0711 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Trypanosoma cruzi cdc2-related kinase 3 0.0522 0.0309 0.0318
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus granulosus ephrin type A receptor 4 A 0.0338 0.0103 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Brugia malayi Hr1 repeat family protein 0.1738 0.1666 0.1698
Echinococcus multilocularis tyrosine protein kinase ABL1 0.233 0.2328 0.2328
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1127 0.0984 0.0984
Echinococcus granulosus tyrosine protein kinase csk 0.0265 0.0022 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0852 0.0678 0.6312
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis casein kinase I alpha 0.065 0.0452 0.0452
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Brugia malayi Protein kinase domain 0.0402 0.0176 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.1738 0.1666 0.4054
Entamoeba histolytica hypothetical protein 0.0267 0.0025 0.0199
Brugia malayi Protein kinase domain containing protein 0.0495 0.0278 0.0267
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0852 0.0678 0.0698
Entamoeba histolytica hypothetical protein, conserved 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.1087 0.0939 0.0949
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0265 0.0022 0.0006
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2235 0.2221 0.2271
Brugia malayi Protein kinase domain containing protein 0.0513 0.0299 0.0288
Loa Loa (eye worm) AGC/PKA protein kinase 0.0852 0.0678 0.0679
Schistosoma mansoni protein kinase 0.0402 0.0176 0.0384
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Trypanosoma cruzi cdc2-related kinase 1 0.0522 0.0309 0.0318
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0453 0.0232 0.0219
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Echinococcus granulosus casein kinase I delta 0.065 0.0452 0.0446
Echinococcus granulosus dual specificity 0.1367 0.1253 0.1272
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1197 0.1062 0.1093
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK/EPH protein kinase 0.0357 0.0125 0.0109
Echinococcus multilocularis neuroglian 0.0341 0.0107 0.0107
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Schistosoma mansoni protein kinase C mu 0.1125 0.0982 0.237
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni hypothetical protein 0.0343 0.0109 0.0221
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Giardia lamblia Kinase, CK1 Casein kinase 0.065 0.0452 0.3727
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2317 0.2313 0.2365
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.065 0.0452 0.0446
Echinococcus multilocularis mitogen activated protein kinase 14 0.895 0.9716 0.9716
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0691 0.0498 0.1177
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0712 0.0521 0.0517
Brugia malayi hypothetical protein 0.2914 0.2979 0.3052
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0265 0.0022 0.0181
Echinococcus multilocularis peroxidasin 0.0305 0.0067 0.0067
Echinococcus multilocularis TGF beta receptor type 1 0.0903 0.0735 0.0735
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1125 0.0982 0.0993
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0265 0.0022 0.0181
Echinococcus granulosus serine:threonine protein kinase N2 0.1738 0.1666 0.1698
Trypanosoma brucei Flagellum attachment zone protein 20 0.0265 0.0022 0.0023
Schistosoma mansoni protein kinase 0.2497 0.2513 0.6138
Entamoeba histolytica ankyrin repeat protein 0.0265 0.0022 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.1684 0.1606 0.1636
Trichomonas vaginalis CMGC family protein kinase 0.1197 0.1062 0.8749
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2317 0.2313 0.2365
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus protein kinase 0.0988 0.0829 0.0834
Echinococcus multilocularis casein kinase I alpha 0.065 0.0452 0.0452
Brugia malayi Protein kinase domain containing protein 0.3945 0.413 0.4239
Giardia lamblia Kinase, CMGC CLK 0.1124 0.098 0.8076
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1197 0.1062 0.1062
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0522 0.0309 0.0298
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus multilocularis dual specificity 0.0307 0.0069 0.0069
Trypanosoma brucei cdc2-related kinase 3 0.0522 0.0309 0.0318
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0402 0.0176 0.0176
Brugia malayi Doublecortin family protein 0.032 0.0084 0.0066
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Onchocerca volvulus 0.0922 0.0755 0.0865
Plasmodium falciparum tyrosine kinase-like protein 0.0265 0.0022 0.0023
Entamoeba histolytica protein kinase, putative 0.1367 0.1253 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.0605 0.0402 0.3663
Loa Loa (eye worm) hypothetical protein 0.0605 0.0402 0.0394
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2317 0.2313 0.2365
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Furin-like cysteine rich region family protein 0.1125 0.0982 0.0993
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0327 0.0091 0.0094
Brugia malayi SRC-1 0.1127 0.0984 0.0995
Brugia malayi Fibronectin type III domain containing protein 0.0702 0.051 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0852 0.0678 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.0605 0.0402 0.3307
Brugia malayi Protein kinase domain containing protein 0.0495 0.0278 0.0267
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.1197 0.1062 0.8478
Schistosoma mansoni serine/threonine protein kinase 0.1785 0.1718 0.4182
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0174 0.0381
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0597 0.0393 0.0393
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0605 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0831 0.0653 0.0654
Echinococcus multilocularis ephrin type A receptor 4 A 0.0338 0.0103 0.0103
Loa Loa (eye worm) AGC/PKG protein kinase 0.0302 0.0063 0.0045
Entamoeba histolytica protein kinase , putative 0.0686 0.0492 0.3931
Echinococcus granulosus aurora kinase A 0.0686 0.0492 0.0488
Schistosoma mansoni tyrosine kinase 0.1529 0.1434 0.3481
Schistosoma mansoni septate junction protein 0.0302 0.0064 0.0108
Plasmodium falciparum cGMP-dependent protein kinase 0.0302 0.0063 0.042
Echinococcus granulosus tyrosine kinase 0.0265 0.0022 0.0002
Echinococcus granulosus serine:threonine protein kinase MARK2 0.055 0.034 0.033
Loa Loa (eye worm) TK/RYK protein kinase 0.0265 0.0022 0.0002
Echinococcus multilocularis serine:threonine protein kinase N2 0.0587 0.0382 0.0382
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Echinococcus granulosus TGF beta receptor type 1 0.0903 0.0735 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0799 0.0618 0.1473
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0521 0.0536
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0587 0.0382 0.0374
Entamoeba histolytica protein kinase domain containing protein 0.0312 0.0075 0.0598
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0174 0.0381
Giardia lamblia Kinase, AGC AKT 0.1026 0.0872 0.7183
Schistosoma mansoni titin 0.0302 0.0064 0.0108
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0513 0.0299 0.0288
Trichomonas vaginalis TKL family protein kinase 0.0267 0.0025 0.0205
Plasmodium falciparum serine/threonine protein kinase, putative 0.0686 0.0492 0.4536
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0265 0.0022 0.0022
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0265 0.0022 0.0002
Trypanosoma cruzi casein kinase, putative 0.065 0.0452 0.0466
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0852 0.0678 0.0698
Schistosoma mansoni serine/threonine protein kinase 0.0852 0.0678 0.162
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trypanosoma brucei cdc2-related kinase 1 0.0522 0.0309 0.0318
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus tyrosine protein kinase Src42A 0.1127 0.0984 0.0995
Loa Loa (eye worm) camk/dcamkl protein kinase 0.032 0.0084 0.0066
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0265 0.0022 0.0022
Plasmodium vivax glycogen synthase kinase 3, putative 0.1197 0.1062 1
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0678
Loa Loa (eye worm) AGC/NDR protein kinase 0.0587 0.0382 0.0374
Loa Loa (eye worm) hypothetical protein 0.0965 0.0804 0.0809
Schistosoma mansoni serine/threonine protein kinase 0.0605 0.0402 0.094
Leishmania major protein kinase, putative 0.0265 0.0022 0.0023
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0285 0.0045 0.0026
Echinococcus multilocularis serine:threonine protein kinase 3 0.0441 0.0218 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus natriuretic peptide receptor 1 0.0265 0.0022 0.0002
Schistosoma mansoni protein kinase 0.0451 0.023 0.0518
Entamoeba histolytica protein kinase domain containing protein 0.0451 0.023 0.1836
Brugia malayi Variant SH3 domain containing protein 0.0407 0.0181 0.0166
Onchocerca volvulus 0.0286 0.0045 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0174 0.0381
Echinococcus granulosus Protein kinase C brain isozyme 0.0799 0.0618 0.0617
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0265 0.0022 0.0006
Echinococcus multilocularis tyrosine protein kinase pr2 0.0265 0.0022 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0605 0.0402 0.3663
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0522 0.0309 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Loa Loa (eye worm) hypothetical protein 0.0922 0.0755 0.0758
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trypanosoma cruzi aurora B kinase, putative 0.0686 0.0492 0.0507
Loa Loa (eye worm) hypothetical protein 0.0276 0.0034 0.0015
Loa Loa (eye worm) hypothetical protein 0.0495 0.0278 0.0267
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0395 0.0167 0.0152
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0304 0.0065 0.0438
Loa Loa (eye worm) TK protein kinase 0.1684 0.1606 0.1636
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2579 0.2605 0.2667
Echinococcus multilocularis protein tyrosine kinase 0.3902 0.4082 0.4082
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0265 0.0022 0.0002
Echinococcus granulosus protein kinase 0.0265 0.0022 0.0002
Plasmodium vivax tyrosine kinase-like protein, putative 0.0265 0.0022 0.0023
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Schistosoma mansoni serine/threonine kinase 0.0587 0.0382 0.0892
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis tyrosine protein kinase Fyn 0.095 0.0786 0.0786
Echinococcus granulosus casein kinase I alpha 0.065 0.0452 0.0446
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Echinococcus multilocularis neuroglian 0.0867 0.0694 0.0694
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0686 0.0492 0.3931
Loa Loa (eye worm) hypothetical protein 0.0343 0.0109 0.0093
Brugia malayi protein kinase C3,putative 0.0446 0.0224 0.0211
Loa Loa (eye worm) hypothetical protein 0.1509 0.141 0.1434
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0402 0.0176 0.0161
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0799 0.0618 0.0618
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1197 0.1062 0.1075
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0265 0.0022 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0852 0.0678 0.5582
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni adapter molecule crk 0.0407 0.0181 0.0397
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1154 0.1015 0.1015
Echinococcus multilocularis serine threonine protein kinase 0.0634 0.0434 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Schistosoma mansoni serine/threonine protein kinase 0.0852 0.0678 0.162
Echinococcus multilocularis tyrosine protein kinase csk 0.0265 0.0022 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0686 0.0492 0.4056
Echinococcus multilocularis integrin linked protein kinase 0.0265 0.0022 0.0022
Plasmodium vivax serine/threonine kinase-1, putative 0.1124 0.098 0.9216
Trypanosoma brucei Casein kinase II 0.0263 0.002 0.002
Schistosoma mansoni kinase 0.0435 0.0212 0.0473
Entamoeba histolytica cell division protein kinase 2, putative 0.0522 0.0309 0.2466
Entamoeba histolytica PH domain containing protein kinase, putative 0.0373 0.0142 0.1137
Entamoeba histolytica protein kinase, putative 0.0424 0.0199 0.1591
Echinococcus multilocularis mitogen activated protein kinase 11 0.895 0.9716 0.9716
Echinococcus granulosus neuroglian 0.0341 0.0107 0.009
Echinococcus multilocularis tyrosine protein kinase Srms 0.095 0.0786 0.0786
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0265 0.0022 0.0002
Plasmodium falciparum protein serine/threonine kinase-1 0.1124 0.098 0.9216
Loa Loa (eye worm) TK/FAK protein kinase 0.3945 0.413 0.4239
Loa Loa (eye worm) hypothetical protein 0.0852 0.0678 0.0679
Giardia lamblia Kinase, AGC PKA 0.0327 0.0091 0.0752
Loa Loa (eye worm) protein kinase domain-containing protein 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Echinococcus multilocularis dual specificity 0.1367 0.1253 0.1253
Echinococcus granulosus protein kinase c epsilon type 0.0754 0.0568 0.0565
Loa Loa (eye worm) hypothetical protein 0.0612 0.0409 0.0402
Brugia malayi protein unc-22 0.0429 0.0205 0.0192
Brugia malayi cyclin-dependent kinase 7 homolog 0.0741 0.0553 0.055
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0382 0.0892
Schistosoma mansoni tyrosine kinase 0.0456 0.0236 0.0532
Brugia malayi Protein kinase domain containing protein 0.225 0.2238 0.2288
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0605 0.0402 0.3663
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0587 0.0382 0.0382
Brugia malayi Protein kinase domain containing protein 0.0774 0.059 0.0588
Brugia malayi ephrin receptor 1 precursor 0.0299 0.006 0.0042
Echinococcus granulosus cyclin dependent kinase 1 0.0522 0.0309 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0401 0.0174 0.1432
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3007 0.3083 0.3083
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus serine:threonine protein kinase MARK2 0.055 0.034 0.033
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Entamoeba histolytica hypothetical protein 0.0268 0.0026 0.0205
Onchocerca volvulus 0.0429 0.0205 0.0216
Echinococcus multilocularis tyrosine protein kinase 0.0265 0.0022 0.0022
Schistosoma mansoni tyrosine kinase 0.0703 0.0511 0.1209
Brugia malayi Fes/CIP4 homology domain containing protein 0.0819 0.0641 0.0641
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0107 0.009
Schistosoma mansoni tyrosine kinase 0.0831 0.0653 0.156
Brugia malayi map kinase activated protein kinase protein 2 0.0597 0.0393 0.0385
Brugia malayi hypothetical protein 0.0265 0.0022 0.0002
Echinococcus multilocularis cyclin dependent kinase 1 0.0522 0.0309 0.0309
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0701 0.0509 0.0505
Onchocerca volvulus 0.085 0.0675 0.0771
Plasmodium falciparum protein kinase, putative 0.0265 0.0022 0.0023
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0605 0.0402 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.0069 0.0121
Schistosoma mansoni hypothetical protein 0.0265 0.0022 0.0006
Schistosoma mansoni tyrosine kinase 0.148 0.1379 0.3346
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0445 0.0223 0.1949
Echinococcus multilocularis serine:threonine protein kinase 0.0367 0.0136 0.0136
Schistosoma mansoni tyrosine kinase 0.0507 0.0293 0.0673
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0666 0.047 0.047
Schistosoma mansoni protein kinase 0.0982 0.0822 0.1976
Brugia malayi Egg laying defective protein 4 0.0302 0.0063 0.0045
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0898 0.0729 0.0729
Brugia malayi hypothetical protein 0.0712 0.0521 0.0517
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0401 0.0174 0.0179
Brugia malayi Protein kinase domain containing protein 0.2497 0.2513 0.2571
Loa Loa (eye worm) hypothetical protein 0.0937 0.0772 0.0776
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0302 0.0064 0.0045
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0469 0.025 0.025
Schistosoma mansoni serine/threonine RGC 0.0265 0.0022 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Echinococcus granulosus NCK adaptor protein 0.0407 0.0181 0.0166
Brugia malayi Raf kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.0985 0.0826 0.0831
Loa Loa (eye worm) hypothetical protein 0.0712 0.0521 0.0517
Schistosoma mansoni titin 0.0429 0.0205 0.0457
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1127 0.0984 0.0984
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.028 0.0039 0.0039
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0265 0.0022 0.0175
Entamoeba histolytica casein kinase 1, putative 0.065 0.0452 0.3611
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1124 0.098 0.1009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0605 0.0402 0.0394
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0307 0.0069 0.0051
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1427 0.1319 0.1341
Echinococcus multilocularis N chimaerin 0.0395 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0666 0.047 0.0465
Loa Loa (eye worm) CAMK protein kinase 0.0429 0.0205 0.0192
Giardia lamblia Kinase, CMGC CDK 0.0522 0.0309 0.2545
Brugia malayi Protein kinase domain containing protein 0.1529 0.1434 0.1458
Loa Loa (eye worm) hypothetical protein 0.0401 0.0174 0.0159
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2914 0.2979 0.3052
Echinococcus granulosus tyrosine protein kinase Fyn 0.1127 0.0984 0.0995
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0382 0.0892
Echinococcus granulosus tyrosine protein kinase Blk 0.095 0.0786 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0265 0.0022 0.0181
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1124 0.098 0.1009
Onchocerca volvulus 0.0495 0.0278 0.0303
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0265 0.0022 0.0006
Schistosoma mansoni cell adhesion molecule 0.0341 0.0107 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis CK1 family protein kinase 0.065 0.0452 0.3727
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0265 0.0022 0.0023
Toxoplasma gondii aurora kinase 0.0686 0.0492 0.4536
Loa Loa (eye worm) hypothetical protein 0.0524 0.0312 0.0301
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0341 0.0107 0.009
Brugia malayi Protein kinase domain containing protein 0.0487 0.027 0.0258
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0302 0.0064 0.0108
Trichomonas vaginalis STE family protein kinase 0.0304 0.0065 0.0538
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Brugia malayi hypothetical protein 0.0265 0.0022 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0493 0.0277 0.0265
Loa Loa (eye worm) hypothetical protein 0.0702 0.051 0.0506
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1197 0.1062 0.1075
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0605 0.0402 0.0394
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1072 0.0923 0.095
Entamoeba histolytica casein kinase, putative 0.065 0.0452 0.3611
Entamoeba histolytica PH domain containing protein kinase, putative 0.0898 0.0729 0.5818
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.895 0.9716 1
Plasmodium falciparum protein kinase 5 0.0522 0.0309 0.2775
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0302 0.0063 0.0063
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0265 0.0022 0.0002
Brugia malayi Protein kinase domain containing protein 0.0831 0.0654 0.0654
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus granulosus serine:threonine protein kinase 0.0367 0.0136 0.012
Entamoeba histolytica serine/threonine protein kinase, putative 0.0348 0.0115 0.0921
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Giardia lamblia Kinase, STE STE20 0.1333 0.1214 1
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0659 0.0462 0.0456
Onchocerca volvulus 0.0495 0.0278 0.0303
Echinococcus multilocularis tyrosine protein kinase csk 0.0265 0.0022 0.0022
Echinococcus multilocularis tyrosine protein kinase Abl 0.1374 0.126 0.126
Giardia lamblia Kinase, NEK 0.0304 0.0065 0.0538
Schistosoma mansoni serine/threonine protein kinase 0.039 0.0162 0.0351
Loa Loa (eye worm) hypothetical protein 0.4666 0.4934 0.5069
Trichomonas vaginalis CAMK family protein kinase 0.0462 0.0242 0.1996
Trichomonas vaginalis AGC family protein kinase 0.0587 0.0382 0.3145
Loa Loa (eye worm) RGC/RGC protein kinase 0.0265 0.0022 0.0002
Echinococcus multilocularis casein kinase I gamma 0.0391 0.0163 0.0163
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Brugia malayi Protein kinase domain containing protein 0.0659 0.0462 0.0456
Trypanosoma cruzi protein kinase, putative 0.0265 0.0022 0.0023
Brugia malayi Protein kinase domain containing protein 0.0831 0.0654 0.0654
Echinococcus multilocularis natriuretic peptide receptor 1 0.0265 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.0147 0.0314
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0335 0.0101 0.0084
Entamoeba histolytica protein kinase, putative 0.0402 0.0176 0.1402
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) hypothetical protein 0.1181 0.1045 0.1057
Echinococcus multilocularis activin receptor type 0.4113 0.4317 0.4317
Echinococcus granulosus TGF-beta receptor type-1 0.0903 0.0735 0.0738
Echinococcus multilocularis roundabout 2 0.0341 0.0107 0.0107
Schistosoma mansoni serine/threonine-protein kinase 0.0373 0.0142 0.0302
Entamoeba histolytica PH domain containing protein kinase, putative 0.0373 0.0142 0.1137
Echinococcus multilocularis beta adrenergic receptor kinase 0.0329 0.0094 0.0094
Plasmodium vivax tyrosine kinase-like protein, putative 0.0265 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.1513 0.1415 0.144
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Trypanosoma brucei aurora B kinase 0.0686 0.0492 0.0507
Echinococcus granulosus epidermal growth factor receptor 0.1125 0.0982 0.0993
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1513 0.1415 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Loa Loa (eye worm) hypothetical protein 0.0922 0.0755 0.0758
Echinococcus granulosus tyrosine protein kinase csk 0.0265 0.0022 0.0002
Brugia malayi bone morphogenetic protein type 1 receptor 0.0982 0.0822 0.0828
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0462 0.0242 0.023
Giardia lamblia Kinase, CAMK CAMKL 0.0445 0.0223 0.1835
Giardia lamblia Kinase, CMGC CK2 0.0263 0.002 0.0162
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Trypanosoma cruzi casein kinase, putative 0.065 0.0452 0.0466
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus multilocularis tyrosine protein kinase Blk 0.095 0.0786 0.0786
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.028 0.0039 0.002
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0402 0.0176 0.0176
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0597 0.0393 0.0385
Loa Loa (eye worm) hypothetical protein 0.0831 0.0654 0.0654
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0329 0.0094 0.0077
Echinococcus multilocularis protein kinase c epsilon type 0.0754 0.0568 0.0568
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2317 0.2313 0.2313
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1333 0.1214 0.125
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0522 0.0309 0.2775
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0512 0.0298 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0379 0.015 0.032
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1472 0.137 0.1392
Schistosoma mansoni atypical protein kinase C 0.0854 0.0679 0.1623
Echinococcus granulosus mitogen activated protein kinase 11 0.895 0.9716 1
Echinococcus granulosus dual specificity protein kinase clk2 0.1124 0.098 0.0991
Schistosoma mansoni serine/threonine protein kinase 0.1367 0.1253 0.3036
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Echinococcus multilocularis roundabout 2 0.0341 0.0107 0.0107
Entamoeba histolytica ankyrin repeat protein 0.0265 0.0022 0.0175
Echinococcus granulosus rho-associated protein kinase 1 0.085 0.0675 0.0676
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0852 0.0678 0.0698
Loa Loa (eye worm) hypothetical protein 0.0575 0.0368 0.0359
Echinococcus multilocularis NCK adaptor protein 0.0424 0.0199 0.0199
Echinococcus granulosus roundabout 2 0.0341 0.0107 0.009
Plasmodium falciparum calcium-dependent protein kinase 4 0.0605 0.0402 0.3663
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0402 0.0176 0.0161
Entamoeba histolytica hypothetical protein 0.0432 0.0209 0.1665
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1154 0.1015 0.1026
Trichomonas vaginalis CMGC family protein kinase 0.1197 0.1062 0.8749
Schistosoma mansoni tyrosine kinase 0.1127 0.0984 0.2375
Echinococcus multilocularis rho associated protein kinase 0.085 0.0675 0.0675
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.0309 0.0712
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Echinococcus multilocularis tyrosine protein kinase csk 0.0265 0.0022 0.0022
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0401 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Plasmodium vivax protein kinase Crk2 0.0522 0.0309 0.2775
Schistosoma mansoni tyrosine kinase 0.0967 0.0806 0.1937
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.0975 0.2352
Loa Loa (eye worm) AGC/AKT protein kinase 0.0774 0.059 0.0588
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.023 0.0237
Entamoeba histolytica tyrosin kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0313 0.0076 0.0059
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0348 0.0115 0.0119
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2497 0.2513 0.2571
Brugia malayi protein kinase C II. 0.0754 0.0568 0.0565
Entamoeba histolytica protein kinase, putative 0.0686 0.0492 0.3931
Echinococcus multilocularis tyrosine protein kinase HCK 0.072 0.053 0.053
Echinococcus granulosus roundabout 2 0.1004 0.0847 0.0853
Echinococcus granulosus cyclin dependent kinase 9 0.0435 0.0212 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.085 0.0675 0.1613
Trichomonas vaginalis STE family protein kinase 0.1333 0.1214 1
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Variant SH3 domain containing protein 0.0407 0.0181 0.0166
Echinococcus granulosus mitogen activated protein kinase 14 0.895 0.9716 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0852 0.0678 0.0679
Schistosoma mansoni serine/threonine kinase 0.0506 0.0291 0.0668
Brugia malayi Protein kinase domain containing protein 0.0522 0.0309 0.0298
Echinococcus multilocularis tyrosine protein kinase shark 0.0737 0.0549 0.0549
Schistosoma mansoni nephrin 0.0341 0.0107 0.0215
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1427 0.1319 0.1341
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1127 0.0984 0.0984
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0094 0.0183
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Echinococcus multilocularis MAM 0.0343 0.0109 0.0109
Giardia lamblia Kinase, PLK 0.0348 0.0115 0.095
Echinococcus granulosus c-Jun N-terminal kinases 0.3007 0.3083 0.316
Echinococcus granulosus tyrosine protein kinase shark 0.0737 0.0549 0.0546
Echinococcus multilocularis slit 2 protein 0.0289 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0065 0.0538
Echinococcus multilocularis twitchin 0.039 0.0162 0.0162
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0265 0.0022 0.0023
Onchocerca volvulus 0.0364 0.0132 0.013
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1127 0.0984 0.0984
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1367 0.1253 0.1289
Echinococcus granulosus tyrosine protein kinase HCK 0.072 0.053 0.0526
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Giardia lamblia Kinase, CAMK CAMKL 0.0445 0.0223 0.1835
Toxoplasma gondii STE kinase 0.0265 0.0022 0.0023
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1472 0.137 0.1392
Leishmania major protein kinase, putative 0.1124 0.098 0.1009
Echinococcus granulosus tyrosine protein kinase Src64B 0.1127 0.0984 0.0995
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni protein kinase 0.0451 0.023 0.0518
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0302 0.0063 0.042
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis tyrosine protein kinase otk 0.0302 0.0064 0.0064
Echinococcus multilocularis protein KINase family member (kin 25) 0.0831 0.0653 0.0653
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.0568 0.135
Echinococcus multilocularis lachesin 0.0302 0.0064 0.0064
Schistosoma mansoni protein kinase 0.065 0.0452 0.1065
Schistosoma mansoni protein kinase 0.0451 0.023 0.0518
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Giardia lamblia Kinase, NEK 0.0304 0.0065 0.0538
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica tyrosin kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0697 0.0505 0.1194
Echinococcus granulosus roundabout 2 0.0341 0.0107 0.009
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0852 0.0678 0.6312
Brugia malayi Protein kinase domain containing protein 0.2317 0.2313 0.2365
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0367 0.0136 0.012
Echinococcus granulosus tyrosine protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0265 0.0022 0.0022
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Trypanosoma brucei polo-like protein kinase 0.0348 0.0115 0.0119
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0464 0.0244 0.0252
Brugia malayi C1-like domain containing protein 0.1125 0.0982 0.0993
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Trypanosoma cruzi Protein kinase B 0.0373 0.0142 0.0147
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.023 0.0237
Schistosoma mansoni vav2 0.0441 0.0219 0.049
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0597 0.0393 0.0385
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0605 0.0402 0.0413
Brugia malayi P38 map kinase family protein 2 0.895 0.9716 1
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0265 0.0022 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni tyrosine kinase 0.0703 0.0511 0.1209
Echinococcus granulosus activin receptor type 0.4113 0.4317 0.4432
Entamoeba histolytica protein kinase, putative 0.0686 0.0492 0.3931
Loa Loa (eye worm) hypothetical protein 0.0939 0.0775 0.0779
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2914 0.2979 0.3052
Echinococcus granulosus serine:threonine protein kinase N2 0.1151 0.1011 0.1023
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1472 0.137 0.1392
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2317 0.2313 0.2365
Echinococcus multilocularis serine:threonine protein kinase N2 0.1151 0.1011 0.1011
Loa Loa (eye worm) TK/Met protein kinase 0.0265 0.0022 0.0002
Giardia lamblia Kinase, AGC PKA 0.0852 0.0678 0.5582
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0373 0.0142 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0852 0.0678 0.162
Brugia malayi hypothetical protein 0.0495 0.0278 0.0267
Echinococcus granulosus cyclin dependent kinase 9 0.0478 0.026 0.0248
Echinococcus granulosus activated cdc42 kinase 1 0.1734 0.1662 0.1694
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0107 0.009
Brugia malayi Protein kinase domain containing protein 0.1734 0.1662 0.1694
Trichomonas vaginalis CMGC family protein kinase 0.0522 0.0309 0.2545
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0341 0.0107 0.0107
Trichomonas vaginalis STE family protein kinase 0.0402 0.0176 0.1447
Toxoplasma gondii AGC kinase 0.0852 0.0678 0.6312
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0697 0.0505 0.05
Brugia malayi C-terminal src kinase protein 1 0.0265 0.0022 0.0002
Echinococcus granulosus tyrosine protein kinase pr2 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Giardia lamblia Kinase, CMGC GSK 0.1197 0.1062 0.8749
Schistosoma mansoni protein kinase 0.0903 0.0735 0.176
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0063 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0022 0.0006
Echinococcus multilocularis Immunoglobulin 0.0663 0.0467 0.0467
Schistosoma mansoni tyrosine kinase 0.1127 0.0984 0.2375
Echinococcus multilocularis growth factor receptor bound protein 2 0.0407 0.0181 0.0181
Echinococcus granulosus tyrosine kinase 0.0495 0.0278 0.0267
Schistosoma mansoni growth factor receptor-bound protein 0.0407 0.0181 0.0397
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Echinococcus granulosus cyclin dependent kinase 7 0.0697 0.0505 0.05
Trypanosoma cruzi casein kinase, putative 0.065 0.0452 0.0466
Loa Loa (eye worm) hypothetical protein 0.0702 0.051 0.0506
Entamoeba histolytica protein kinase, putative 0.0605 0.0402 0.3205
Echinococcus multilocularis fibroblast growth factor receptor 4 0.148 0.1379 0.1379
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0407 0.0181 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0392 0.0164 0.1351
Entamoeba histolytica protein kinase 2, putative 0.0327 0.0091 0.0729
Brugia malayi Peroxidasin 0.0305 0.0067 0.0049
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) thyroid receptor interactor 0.0819 0.0641 0.0641
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0587 0.0382 0.3145
Echinococcus granulosus slit 2 protein 0.0289 0.0049 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.0022 0.0181
Echinococcus granulosus cGMP dependent protein kinase 1 0.0302 0.0063 0.0045
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2497 0.2513 0.2513
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus lachesin 0.0302 0.0064 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0022 0.0006
Echinococcus granulosus protein tyrosine kinase 0.3902 0.4082 0.4189
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0798 0.0617 0.0616
Echinococcus multilocularis epidermal growth factor receptor 0.0967 0.0806 0.0806
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1333 0.1214 0.1232
Brugia malayi serine/threonine protein kinase 6 0.0686 0.0492 0.0488
Giardia lamblia Kinase, NEK 0.0265 0.0022 0.0181
Trichomonas vaginalis AGC family protein kinase 0.0774 0.059 0.4858
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0335 0.0101 0.0084
Trichomonas vaginalis STE family protein kinase 0.1333 0.1214 1
Plasmodium vivax protein kinase, putative 0.0282 0.0041 0.0206
Brugia malayi Tyrosine-protein kinase PR2 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0407 0.0181 0.0397
Echinococcus multilocularis casein kinase i 0.065 0.0452 0.0452
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0679
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0747 0.056 0.0558
Echinococcus multilocularis calcium activated potassium channel 0.0369 0.0138 0.0138
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0265 0.0022 0.0002
Entamoeba histolytica cysteine surface protein, putative 0.0265 0.0022 0.0175
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0402 0.0176 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.028 0.0039 0.0318
Echinococcus multilocularis cyclin dependent kinase 0.0522 0.0309 0.0309
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.895 0.9716 1
Brugia malayi SH2 domain containing protein 0.0495 0.0278 0.0267
Entamoeba histolytica protein kinase, putative 0.0774 0.059 0.4708
Loa Loa (eye worm) hypothetical protein 0.0407 0.0181 0.0166
Entamoeba histolytica hypothetical protein 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0493 0.0277 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Brugia malayi EGF-like domain containing protein 0.0289 0.0049 0.003
Leishmania major protein kinase A catalytic subunit 0.0852 0.0678 0.0698
Echinococcus multilocularis c src tyrosine kinase 0.0672 0.0477 0.0477
Echinococcus multilocularis 0.0937 0.0772 0.0772
Plasmodium vivax calcium-dependent protein kinase, putative 0.0605 0.0402 0.3663
Brugia malayi Protein kinase domain containing protein 0.0377 0.0147 0.0132
Leishmania major protein kinase A catalytic subunit isoform 2 0.0852 0.0678 0.0698
Trichomonas vaginalis CMGC family protein kinase 0.0522 0.0309 0.2545
Schistosoma mansoni hypothetical protein 0.0343 0.0109 0.0221
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.028 0.0039 0.0318
Onchocerca volvulus 0.0343 0.0109 0.0103
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.002 0.0162
Brugia malayi Receptor family ligand binding region containing protein 0.0265 0.0022 0.0002
Leishmania major casein kinase II, putative 0.0263 0.002 0.002
Entamoeba histolytica PH domain containing protein kinase, putative 0.0898 0.0729 0.5818
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1472 0.137 0.137
Brugia malayi Protein kinase domain containing protein 0.0587 0.0382 0.0374
Brugia malayi Immunoglobulin I-set domain containing protein 0.0702 0.051 0.0506
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0798 0.0617 0.0616
Echinococcus granulosus twitchin 0.1053 0.0902 0.091
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1786 0.1719 0.1753
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0265 0.0022 0.0181
Entamoeba histolytica p21-activated kinase 0.0448 0.0227 0.1811
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0265 0.0022 0.0175
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0327 0.0091 0.0074
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.023 0.0237
Brugia malayi Immunoglobulin I-set domain containing protein 0.0302 0.0064 0.0045
Brugia malayi Protein kinase domain containing protein 0.1786 0.1719 0.1753
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni nck2/grb4 0.0407 0.0181 0.0397
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2914 0.2979 0.2979
Brugia malayi Cam kinase protein 1 0.0605 0.0402 0.0394
Schistosoma mansoni ephrin receptor 0.0304 0.0065 0.0113
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0302 0.0064 0.0045
Loa Loa (eye worm) AUR protein kinase 0.0686 0.0492 0.0488
Schistosoma mansoni serine/threonine protein kinase 0.055 0.034 0.0788
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0022 0.0175
Echinococcus multilocularis 0.0258 0.0014 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Brugia malayi cyclin-dependent kinase 9 0.0435 0.0212 0.0198
Giardia lamblia Kinase, CMGC GSK 0.1197 0.1062 0.8749
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.0069 0.0568
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0395 0.0167 0.0364
Trypanosoma brucei rac serine-threonine kinase, putative 0.0774 0.059 0.0607
Echinococcus multilocularis aurora kinase A 0.0686 0.0492 0.0492
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.225 0.2238 0.2288
Entamoeba histolytica protein kinase, putative 0.0587 0.0382 0.3047
Trypanosoma brucei protein kinase, putative 0.0451 0.023 0.0237
Echinococcus granulosus tyrosine protein kinase ABL1 0.233 0.2328 0.238
Echinococcus granulosus casein kinase i 0.065 0.0452 0.0446
Brugia malayi Variant SH3 domain containing protein 0.0395 0.0167 0.0152
Brugia malayi hypothetical protein 0.0343 0.0109 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0115 0.095
Echinococcus granulosus casein kinase I alpha 0.065 0.0452 0.0446
Onchocerca volvulus 0.065 0.0452 0.0508
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0265 0.0022 0.0006
Onchocerca volvulus 0.2654 0.2689 0.3148
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.148 0.1379 0.1402
Trypanosoma brucei protein kinase, putative 0.0288 0.0047 0.0049
Echinococcus granulosus c src tyrosine kinase 0.0672 0.0477 0.0471
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0522 0.0309 0.2545
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.0309 0.0712
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Echinococcus granulosus integrin linked protein kinase 0.0265 0.0022 0.0002
Entamoeba histolytica cell division protein kinase 2, putative 0.0565 0.0358 0.2854
Entamoeba histolytica protein kinase domain containing protein 0.0686 0.0492 0.3931
Brugia malayi Protein kinase domain containing protein 0.0391 0.0163 0.0148
Schistosoma mansoni tyrosine kinase 0.0265 0.0022 0.0006
Schistosoma mansoni neuroglian 0.0341 0.0107 0.0215
Loa Loa (eye worm) TK/FER protein kinase 0.0265 0.0022 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.0922 0.0755 0.0758
Entamoeba histolytica protein kinase domain containing protein 0.1197 0.1062 0.8478
Brugia malayi putative serine/threonine kinase SADA gamma 0.0401 0.0174 0.0159
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Brugia malayi Sex muscle abnormal protein 5 0.0407 0.0181 0.0166
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1367 0.1253 0.1289
Brugia malayi Protein kinase domain containing protein 0.0587 0.0382 0.0374
Loa Loa (eye worm) hypothetical protein 0.0302 0.0064 0.0045
Schistosoma mansoni nephrin 0.0906 0.0738 0.1767
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0672 0.0477 0.1125
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0265 0.0022 0.0002
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0265 0.0022 0.0006
Schistosoma mansoni protein tyrosine kinase 0.0265 0.0022 0.0006
Echinococcus granulosus dual specificity mitogen activated protein 0.1333 0.1214 0.1232
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1127 0.0984 0.0995
Schistosoma mansoni tyrosine kinase 0.0737 0.0549 0.1304
Loa Loa (eye worm) hypothetical protein 0.0343 0.0109 0.0093
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0633 0.0433 0.3566
Plasmodium falciparum calcium-dependent protein kinase 3 0.0605 0.0402 0.3663
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0701 0.0509 0.0509
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0341 0.0107 0.0107
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.0174 0.1435
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2497 0.2513 0.2571
Entamoeba histolytica serine/threonine kinase, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK/EGFR protein kinase 0.1125 0.0982 0.0993
Loa Loa (eye worm) TK protein kinase 0.0265 0.0022 0.0002
Echinococcus multilocularis transfer RNA-Thr 0.1734 0.1662 0.1662
Echinococcus multilocularis mitogen activated protein kinase 11 0.895 0.9716 0.9716
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0402 0.0176 0.0176
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0469 0.025 0.0237
Brugia malayi Protein kinase domain containing protein 0.1124 0.098 0.0991
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0302 0.0063 0.0063
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006
Entamoeba histolytica protein kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis STE family protein kinase 0.0378 0.0148 0.122
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1974 0.193 0.197
Entamoeba histolytica protein kinase, putative 0.0728 0.0539 0.43
Trypanosoma cruzi protein kinase, putative 0.0265 0.0022 0.0023
Brugia malayi STE20-like kinase MST 0.0441 0.0218 0.0205
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0686 0.0492 0.3931
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0368 0.0137 0.0121
Echinococcus granulosus raf serine:threonine protein kinase 0.043 0.0206 0.0193
Trichomonas vaginalis CK1 family protein kinase 0.065 0.0452 0.3727
Echinococcus granulosus serine:threonine kinase SAD 1 0.0401 0.0174 0.0159
Echinococcus multilocularis rac serine:threonine kinase 0.0373 0.0142 0.0142
Entamoeba histolytica hypothetical protein 0.0268 0.0026 0.0205
Entamoeba histolytica tyrosin kinase, putative 0.0265 0.0022 0.0175
Trichomonas vaginalis STE family protein kinase 0.0402 0.0176 0.1447
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5484 0.5848 0.6011
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1367 0.1253 0.1289
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0754 0.0568 0.0565
Trypanosoma cruzi casein kinase, putative 0.065 0.0452 0.0466
Toxoplasma gondii protein kinase domain-containing protein 0.0265 0.0022 0.0023
Schistosoma mansoni tyrosine kinase 0.1529 0.1434 0.3481
Echinococcus multilocularis cyclin dependent kinase 7 0.0697 0.0505 0.0505
Loa Loa (eye worm) CAMK/PKD protein kinase 0.096 0.0798 0.0803
Brugia malayi Protein kinase domain containing protein 0.0265 0.0022 0.0002
Trypanosoma cruzi cdc2-related kinase 3 0.0522 0.0309 0.0318
Entamoeba histolytica protein kinase, putative 0.0416 0.0191 0.1524
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.065 0.0452 0.0446
Loa Loa (eye worm) hypothetical protein 0.0636 0.0437 0.043
Schistosoma mansoni kinase 0.0423 0.0198 0.0439
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.2317 0.2313 0.5645
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0265 0.0022 0.0022
Trichomonas vaginalis STE family protein kinase 0.1333 0.1214 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.0136 0.012
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0852 0.0678 0.0679
Loa Loa (eye worm) TK/CSK protein kinase 0.0265 0.0022 0.0002
Loa Loa (eye worm) gastrulation defective protein 1 0.1599 0.1512 0.1539
Trichomonas vaginalis TKL family protein kinase 0.0265 0.0022 0.0181
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0265 0.0022 0.0023
Toxoplasma gondii casein kinase I 0.065 0.0452 0.4152
Echinococcus multilocularis mitogen activated protein kinase 14 0.895 0.9716 0.9716
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1026 0.0872 0.0879
Onchocerca volvulus 0.0774 0.059 0.0671
Brugia malayi protein C17H12.11 0.0612 0.0409 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0138 0.0292
Echinococcus granulosus calcium activated potassium channel 0.0369 0.0138 0.0122
Echinococcus granulosus beta-adrenergic receptor kinase 0.0329 0.0094 0.0077
Brugia malayi Protein kinase domain containing protein 0.5276 0.5615 0.5771
Trypanosoma brucei SNF1-related protein kinases, putative 0.0401 0.0174 0.0179
Entamoeba histolytica tyrosine kinase, putative 0.0265 0.0022 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.1124 0.098 0.2365
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1333 0.1214 0.125
Entamoeba histolytica protein kinase, putative 0.0424 0.0199 0.1591
Loa Loa (eye worm) hypothetical protein 0.0265 0.0022 0.0002
Giardia lamblia Kinase, NEK 0.0265 0.0022 0.0181
Echinococcus granulosus titin 0.0429 0.0205 0.0192
Leishmania major protein kinase, putative 0.0605 0.0402 0.0413
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1974 0.193 0.197
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1125 0.0982 0.0993
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1615 0.1529 0.1557
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0307 0.0069 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0495 0.0278 0.0267
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0686 0.0492 0.0492
Echinococcus granulosus contactin 0.0341 0.0107 0.009
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0265 0.0022 0.0175
Loa Loa (eye worm) TK/ABL protein kinase 0.233 0.2328 0.238
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0587 0.0382 0.0374
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0852 0.0678 0.0678
Schistosoma mansoni protein kinase 0.0265 0.0022 0.0006

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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