Detailed information for compound 1343277

Basic information

Technical information
  • TDR Targets ID: 1343277
  • Name: N-(5-chloro-2-methoxyphenyl)-2-(4-methyl-2-ox o-1,3-thiazol-3-yl)acetamide
  • MW: 312.772 | Formula: C13H13ClN2O3S
  • H donors: 1 H acceptors: 2 LogP: 2.32 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1NC(=O)Cn1c(C)csc1=O)Cl
  • InChi: 1S/C13H13ClN2O3S/c1-8-7-20-13(18)16(8)6-12(17)15-10-5-9(14)3-4-11(10)19-2/h3-5,7H,6H2,1-2H3,(H,15,17)
  • InChiKey: PEZSWWGALHLOJL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(5-chloro-2-methoxy-phenyl)-2-(4-methyl-2-oxo-thiazol-3-yl)acetamide
  • N-(5-chloro-2-methoxyphenyl)-2-(4-methyl-2-oxo-3-thiazolyl)acetamide
  • N-(5-chloro-2-methoxy-phenyl)-2-(2-keto-4-methyl-thiazol-3-yl)acetamide
  • N-(5-chloro-2-methoxy-phenyl)-2-(4-methyl-2-oxo-1,3-thiazol-3-yl)ethanamide
  • T5556988
  • ZINC08391105

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0042 0.0167 0.0268
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.1646 1
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0014
Brugia malayi neuropeptide F receptor 0.0023 0.0053 0.0077
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0017 0.0016 0.0046
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.002 0.0033 0.0053
Leishmania major cytochrome p450-like protein 0.0027 0.0074 0.0118
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0213 0.031
Trichomonas vaginalis esterase, putative 0.0036 0.0134 0.0403
Echinococcus multilocularis geminin 0.0587 0.3501 0.3501
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0079 0.0236
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0036 0.0134 0.0813
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0053 0.0232 0.0372
Entamoeba histolytica hypothetical protein 0.007 0.0338 0.2053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0461 0.046
Brugia malayi MH2 domain containing protein 0.0238 0.1365 0.1988
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0145
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0026 0.0073 0.0438
Echinococcus granulosus neuropeptide receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0361 0.0525
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0653 0.095
Plasmodium vivax acyl-CoA synthetase, putative 0.0031 0.01 0.1797
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0037 0.0053
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0074 0.0107
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.027 0.4871
Loa Loa (eye worm) hypothetical protein 0.1059 0.6384 0.9296
Schistosoma mansoni hypothetical protein 0.0102 0.0535 0.0721
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0011 0.0016
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0361 0.1089
Schistosoma mansoni rotamase 0.01 0.0525 0.0707
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0461 0.046
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0017 0.0016 0.0278
Onchocerca volvulus 0.0023 0.0053 0.0083
Leishmania major GTP-binding protein, putative 0.0043 0.0175 0.0281
Onchocerca volvulus 0.0151 0.0836 0.1309
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0653 0.095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0134 0.0181
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0134 0.0215
Trichomonas vaginalis set domain proteins, putative 0.0462 0.2734 0.8253
Schistosoma mansoni neuropeptide receptor 0.0023 0.0053 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0194 0.0194
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0053 0.0077
Echinococcus multilocularis GPCR, family 2 0.0102 0.0535 0.0535
Schistosoma mansoni 6-phosphofructokinase 0.0098 0.0508 0.0684
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0053 0.0053
Toxoplasma gondii ABC1 family protein 0.0036 0.0134 0.1446
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0046 0.0195 0.0262
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.011 0.0584 0.085
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0053 0.0053
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.003 0.0528
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0102 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0037 0.0049
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0277 0.2994
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0554 0.0889
Plasmodium falciparum phd finger protein, putative 0.006 0.0278 0.5021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0037 0.0036
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.004 0.0154 0.0224
Schistosoma mansoni cpg binding protein 0.0086 0.0439 0.0591
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Probable thioesterase TesA 0.0041 0.0163 0.0261
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0098 0.1759
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0053 0.0077
Mycobacterium ulcerans fatty acid synthase Fas 0.0016 0.0006 0.0008
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0079 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0653 0.095
Onchocerca volvulus 0.0019 0.0026 0.004
Echinococcus multilocularis neuropeptide receptor A26 0.0023 0.0053 0.0053
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0102 0.0535 0.0779
Onchocerca volvulus 0.0023 0.0053 0.0083
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0053 0.0071
Echinococcus granulosus geminin 0.0587 0.3501 0.4714
Schistosoma mansoni jumonji domain containing protein 0.0019 0.003 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0049 0.0872
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0114
Schistosoma mansoni hypothetical protein 0.0034 0.0118 0.0159
Schistosoma mansoni alpha glucosidase 0.0074 0.0361 0.0486
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0103 0.0541 0.0786
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.123 0.7427 1
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0653 0.1048
Echinococcus granulosus 6 phosphofructokinase 0.0098 0.0508 0.0684
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0098 0.0508 0.9179
Onchocerca volvulus Alhambra homolog 0.006 0.0278 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0037 0.0053
Schistosoma mansoni hypothetical protein 0.0102 0.0535 0.0721
Brugia malayi TAR-binding protein 0.0188 0.1059 0.1541
Onchocerca volvulus 0.0121 0.0653 0.1022
Loa Loa (eye worm) hypothetical protein 0.018 0.1009 0.1469
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0194 0.0194
Loa Loa (eye worm) glutaminase 2 0.0556 0.3312 0.4823
Echinococcus multilocularis long chain fatty acid transport protein 4 0.1048 0.6314 0.6313
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0053 0.0232 0.0372
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0053 0.0077
Mycobacterium ulcerans hypothetical protein 0.0133 0.0723 0.1052
Mycobacterium tuberculosis Conserved protein 0.0133 0.0723 0.116
Brugia malayi hypothetical protein 0.0021 0.004 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0098 0.0508 0.1533
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium ulcerans polyketide synthase Pks13 0.0074 0.0363 0.0528
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0422 0.0422
Schistosoma mansoni hypothetical protein 0.007 0.0338 0.0455
Schistosoma mansoni ap endonuclease 0.0036 0.0134 0.0181
Trichomonas vaginalis rotamase, putative 0.0098 0.0511 0.154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Echinococcus multilocularis 6 phosphofructokinase 0.0098 0.0508 0.0508
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0037 0.0053
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0053 0.0071
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0188 0.1059 0.1425
Brugia malayi Pre-SET motif family protein 0.0406 0.2393 0.3484
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0024 0.0056 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1646 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0057
Brugia malayi follicle stimulating hormone receptor 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Entamoeba histolytica phosphofructokinase, putative 0.0098 0.0508 0.3087
Giardia lamblia Methyltransferase like 2 0.0015 0.0002 0.0011
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0053 0.0077
Echinococcus granulosus neuropeptide receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0037 0.0053
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0053 0.0053
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0026 0.0073 0.1302
Trichomonas vaginalis phosphofructokinase, putative 0.0098 0.0508 0.1533
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0403 0.0402
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0098 0.0508 0.3087
Toxoplasma gondii kringle domain-containing protein 0.0019 0.0026 0.0275
Brugia malayi Ets-domain containing protein 0.0046 0.0191 0.0278
Schistosoma mansoni hypothetical protein 0.0062 0.0291 0.0392
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0037 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0037 0.0036
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0025 0.0063 0.1136
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0213 0.031
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0042 0.0167 0.0167
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.004 0.0153 0.1653
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0053 0.0077
Echinococcus multilocularis serotonin receptor 0.0023 0.0053 0.0053
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0031 0.01 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0036 0.0134 0.0212
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0053 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0653 0.095
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0053 0.0053
Echinococcus multilocularis muscleblind protein 0.0457 0.2703 0.2702
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0134 0.0194
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0151 0.0836 0.1217
Onchocerca volvulus 0.0191 0.108 0.169
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0202 0.0319
Mycobacterium tuberculosis Possible toxin MazF4 0.0133 0.0723 0.116
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0098 0.0511 0.0819
Loa Loa (eye worm) proteasome 26S subunit 0.0017 0.0016 0.0022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0361 0.1089
Echinococcus granulosus g protein coupled receptor 0.0023 0.0053 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0023 0.0049 0.0065
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0053 0.0232 0.0372
Onchocerca volvulus 0.0023 0.0053 0.0083
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0053 0.0077
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0361 0.2192
Mycobacterium ulcerans lipoprotein LpqF 0.0068 0.0326 0.0474
Onchocerca volvulus 0.0113 0.0601 0.0941
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0134 0.0194
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.004 0.0705
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0121 0.0653 0.095
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0049 0.0213 0.0342
Brugia malayi ecdysteroid receptor 0.0021 0.0037 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.0098 0.0508 0.1533
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0105 0.0554 0.599
Loa Loa (eye worm) hypothetical protein 0.0059 0.027 0.0392
Brugia malayi PHD-finger family protein 0.006 0.0278 0.0405
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0175 0.1892
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus GA binding protein alpha chain 0.0046 0.0191 0.0257
Brugia malayi Dopamine receptor protein 2 0.0023 0.0053 0.0077
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0194 0.0262
Mycobacterium tuberculosis Toxin MazF6 0.0133 0.0723 0.116
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0653 0.1048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0105 0.0554 0.0889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0053 0.0072
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0053 0.0072
Onchocerca volvulus 0.0046 0.0194 0.0304
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0074 0.0363 0.0582
Brugia malayi RNA recognition motif domain containing protein 0.0188 0.1059 0.1541
Brugia malayi Glycosyl hydrolases family 31 protein 0.0332 0.1938 0.2822
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0036 0.0134 1
Schistosoma mansoni ran 0.0043 0.0175 0.0236
Loa Loa (eye worm) fli-1 protein 0.0139 0.0762 0.1109
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0026 0.0073 0.0217
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0653 0.095
Trichomonas vaginalis ran, putative 0.0043 0.0175 0.0528
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0175 0.0277
Toxoplasma gondii aldehyde dehydrogenase 0.0024 0.0056 0.0604
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0037 0.0053
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.011 0.0584 0.0938
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium ulcerans polyketide synthase Pks9 0.0033 0.0111 0.0161
Toxoplasma gondii type I fatty acid synthase, putative 0.0035 0.0126 0.1362
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0202 0.0609
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0079 0.0114
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0037 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0102 0.0535 0.072
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0028 0.0083 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0031 0.0555
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0105 0.0554 0.0806
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0653 0.095
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0049 0.0872
Loa Loa (eye worm) MBCTL1 0.0053 0.0233 0.0339
Schistosoma mansoni amine GPCR 0.0023 0.0053 0.0072
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0053 0.0071
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0053 0.0071
Echinococcus multilocularis dnaJ subfamily B 0.123 0.7427 0.7427
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi N-terminal motif family protein 0.018 0.1009 0.1469
Loa Loa (eye worm) hypothetical protein 0.006 0.0278 0.0405
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0037 0.0049
Echinococcus granulosus somatostatin receptor 0.0023 0.0053 0.0071
Mycobacterium ulcerans polyketide synthase MbtD 0.0015 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0005 0.0048
Mycobacterium tuberculosis Conserved protein 0.0015 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.008 0.0403 0.0542
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0134 0.2414
Schistosoma mansoni amine GPCR 0.0995 0.5993 0.807
Schistosoma mansoni rab6-interacting 0.0021 0.004 0.0053
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0105 0.0554 0.0889
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.0236
Onchocerca volvulus 0.0036 0.0134 0.0209
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0134 0.0403
Plasmodium falciparum acyl-CoA synthetase 0.0031 0.01 0.1797
Brugia malayi beta-lactamase 0.0036 0.0134 0.0194
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0194 0.0282
Schistosoma mansoni neuropeptide receptor 0.0023 0.0053 0.0072
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0055 0.0074
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.0356 0.0355
Loa Loa (eye worm) hypothetical protein 0.0102 0.0535 0.0779
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.011 0.0584 0.0938
Echinococcus multilocularis GA binding protein alpha chain 0.0046 0.0191 0.0191
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0175 0.0235
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0024 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0403 0.0402
Mycobacterium ulcerans beta-lactamase 0.0036 0.0134 0.0194
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0134 0.0215
Mycobacterium leprae Polyketide synthase Pks13 0.0074 0.0363 0.0582
Loa Loa (eye worm) beta-lactamase 0.0036 0.0134 0.0194
Toxoplasma gondii type I fatty acid synthase, putative 0.0067 0.0321 0.3475
Schistosoma mansoni tar DNA-binding protein 0.0188 0.1059 0.1425
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0053 0.0072
Schistosoma mansoni Smad4 0.0016 0.001 0.0014
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0361 0.1089
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0233 0.0233
Echinococcus multilocularis sentrin specific protease 1 0.0046 0.0195 0.0194
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Schistosoma mansoni opsin-like receptor 0.0023 0.0053 0.0072
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.0205 0.0298
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Onchocerca volvulus 0.0023 0.0053 0.0083
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0105 0.0554 0.0876
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0053 0.0232 0.0337
Schistosoma mansoni hypothetical protein 0.008 0.0403 0.0542
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 0.0015 0.0001 0.0001
Toxoplasma gondii phosphofructokinase PFKII 0.0026 0.0073 0.078
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0134 0.0403
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0074 0.0107
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0037 0.005
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.011 0.0584 0.0938
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.1335 0.2144
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0072
Mycobacterium tuberculosis Hypothetical protein 0.0015 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0134 0.0404
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0361 0.1089
Echinococcus multilocularis sex peptide receptor 0.0023 0.0053 0.0053
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0202 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0037 0.0053
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0202 0.0609
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.1044 0.1405
Echinococcus granulosus RUN 0.0021 0.004 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0037 0.005
Leishmania major ATP-dependent phosphofructokinase 0.0098 0.0508 0.0816
Schistosoma mansoni hypothetical protein 0.0627 0.3741 0.5037
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0134 0.2418
Loa Loa (eye worm) latrophilin receptor protein 2 0.0102 0.0535 0.0779
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0105 0.0554 1
Brugia malayi Cytochrome P450 family protein 0.0027 0.0077 0.0111
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.003 0.0528
Brugia malayi hypothetical protein 0.0021 0.004 0.0057
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0098 0.0154
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0072
Onchocerca volvulus 0.0023 0.0053 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0037 0.0053
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0461 0.067
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Entamoeba histolytica acyl-CoA synthetase, putative 0.0126 0.0684 0.4152
Brugia malayi exodeoxyribonuclease III family protein 0.0036 0.0134 0.0195
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0134 0.0403
Echinococcus multilocularis survival motor neuron protein 1 0.0305 0.1775 0.1774
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0653 0.095
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0053 0.0053
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.004 0.0158 0.0254
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.1646 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0039 0.015 0.0218
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0049 0.0213 0.0342
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0005 0.0004
Onchocerca volvulus 0.1059 0.6384 1
Echinococcus multilocularis importin subunit beta 1 0.0059 0.027 0.0269
Mycobacterium ulcerans glutaminase 0.0556 0.3312 0.4823
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0037 0.0053
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0461 0.067
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0105 0.0554 0.0806
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.0221 0.126 0.1834
Schistosoma mansoni AMP dependent ligase 0.0015 0.0001 0.0001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0332 0.1938 0.2822
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0584 0.085
Schistosoma mansoni alpha-glucosidase 0.0285 0.1656 0.223
Schistosoma mansoni tar DNA-binding protein 0.0188 0.1059 0.1425
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0019 0.0026 0.0459
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0134 0.0215
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0053 0.0072
Schistosoma mansoni hypothetical protein 0.0221 0.126 0.1696
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0077 0.0111
Schistosoma mansoni hypothetical protein 0.002 0.0031 0.0042
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0403 0.0586
Trichomonas vaginalis rotamase, putative 0.01 0.0525 0.1584
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.003 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0372 0.6707
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.0236
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0145
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0005 0.0048
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0005 0.0081
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0055 0.0055
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0041 0.0163 0.0261
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0679 0.0913
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0053 0.0053
Mycobacterium leprae Probable polyketide synthase Pks1 0.0053 0.0232 0.0372
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Brugia malayi latrophilin 2 splice variant baaae 0.0221 0.126 0.1834
Echinococcus granulosus survival motor neuron protein 1 0.0305 0.1775 0.2389
Loa Loa (eye worm) hypothetical protein 0.0105 0.0554 0.0806
Schistosoma mansoni smad 0.0016 0.001 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0386 0.0519
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0023 0.0049 0.007
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0023 0.0049 0.0293
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0053 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0554 0.0889
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0037 0.0036
Brugia malayi PHD-finger family protein 0.0025 0.0061 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) acyl carrier protein 0.0023 0.005 0.0072
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0278 0.0405
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.001 0.0013
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0255 0.1468 0.1468
Onchocerca volvulus 0.0036 0.0134 0.0209
Brugia malayi jmjC domain containing protein 0.0197 0.1113 0.1621
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0042 0.0167 0.0225
Onchocerca volvulus 0.0021 0.004 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0175 0.3159
Schistosoma mansoni hypothetical protein 0.006 0.0278 0.0375
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0653 0.095
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0053 0.0232 0.0372
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.001 0.0014
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0175 0.3159
Schistosoma mansoni loxhd1 0.0021 0.004 0.0053
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0361 0.0485
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0022 0.0046 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.003 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0011 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0053 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0037 0.0053
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0105 0.0554 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0461 0.062
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0277 0.0277
Schistosoma mansoni acetyl-CoA synthetase 0.0105 0.0554 0.0746
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0017 0.0016 0.0024
Brugia malayi G protein-coupled receptor 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0011 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0053 0.0083
Schistosoma mansoni hypothetical protein 0.0021 0.004 0.0053
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0037 0.0057
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0036 0.0134 0.2418
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0098 0.0508 0.0804
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0031 0.0332
Schistosoma mansoni gabp alpha 0.0046 0.0191 0.0258
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.004 0.0053
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0403 0.0541
Brugia malayi Doublecortin family protein 0.0021 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0105 0.0554 0.0889
Brugia malayi glutaminase DH11.1 0.0556 0.3312 0.4823
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0043
Trypanosoma brucei beta lactamase 0.0068 0.0326 0.588
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0105 0.0554 0.0553
Schistosoma mansoni amine GPCR 0.0023 0.0053 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0037 0.0053
Loa Loa (eye worm) TAR-binding protein 0.0188 0.1059 0.1541
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0102 0.0535 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0037 0.0053
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0037 0.005
Brugia malayi Melatonin receptor type 1A 0.0023 0.0053 0.0077
Leishmania major pantothenate kinase subunit, putative 0.0022 0.0046 0.0072
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0094 0.0484 0.0704
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.003 0.0316
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0037 0.0057
Brugia malayi RNA binding protein 0.0188 0.1059 0.1541
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0105 0.0554 0.0745
Brugia malayi steroid hormone receptor 0.0021 0.0037 0.0053
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0031 0.0332
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0323 0.1884 0.2742
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0031 0.01 0.016
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0372 0.6707
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.0669 0.0974
Echinococcus multilocularis muscleblind protein 1 0.0457 0.2703 0.2702
Plasmodium vivax acetyl-CoA synthetase, putative 0.0105 0.0554 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0233 0.0339
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0233 0.0314
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.018 0.1009 0.158
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0278 0.0375
Toxoplasma gondii propionate-CoA ligase 0.0105 0.0554 0.599
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0053 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0037 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0134 0.2414
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0105 0.0554 0.599
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0037 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0042 0.0167 0.0268
Brugia malayi phosphofructokinase 0.0098 0.0508 0.0739
Mycobacterium tuberculosis Conserved protein 0.0036 0.0134 0.0215
Brugia malayi nuclear receptor NHR-88 0.0021 0.0037 0.0053
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0134 0.0215
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0361 0.3904
Onchocerca volvulus 0.0023 0.0053 0.0083
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0188 0.1059 0.1541
Brugia malayi Importin beta-1 subunit 0.0059 0.027 0.0392
Brugia malayi Bromodomain containing protein 0.006 0.0278 0.0405
Plasmodium vivax importin-beta 2, putative 0.0059 0.027 0.4871
Brugia malayi larval opioid receptor 0.0023 0.0053 0.0077
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.002 0.0031 0.0044
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0403 0.0542
Echinococcus multilocularis peregrin 0.006 0.0278 0.0278
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.027 0.4871
Brugia malayi GnHR receptor homolog 0.0023 0.0053 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0118 0.0158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0277 0.0373
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.001 0.001
Brugia malayi jmjC domain containing protein 0.0019 0.003 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0053 0.0053
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0036 0.0134 0.018
Schistosoma mansoni amine GPCR 0.0023 0.0053 0.0072
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0053 0.0053
Loa Loa (eye worm) oxidoreductase 0.0105 0.0554 0.0806
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0253 0.0339
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0197 0.1113 0.1499
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0053 0.0071
Brugia malayi Fli-1 protein 0.0139 0.0762 0.1109
Loa Loa (eye worm) doublecortin family protein 0.0021 0.004 0.0057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0005 0.0006
Schistosoma mansoni myosin xvIII 0.0023 0.0053 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0037 0.0053
Brugia malayi nuclear hormone receptor 0.0021 0.0037 0.0053
Brugia malayi Kringle domain containing protein 0.0019 0.0026 0.0037
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0037 0.0036
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0554 0.0889
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0037 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0277 0.0373
Trichomonas vaginalis helicase, putative 0.002 0.0031 0.0091
Loa Loa (eye worm) transcription factor SMAD2 0.0238 0.1365 0.1988
Schistosoma mansoni biogenic amine receptor 0.0023 0.0053 0.0072
Brugia malayi jmjC domain containing protein 0.0019 0.003 0.0043
Echinococcus granulosus long chain fatty acid transport protein 4 0.1048 0.6314 0.8501
Plasmodium vivax sentrin-specific protease 1, putative 0.0046 0.0195 0.3509
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0175 0.0254
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0053 0.0072
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0213 0.031
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0098 0.0508 0.0816
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0134 0.0403
Onchocerca volvulus 0.0462 0.2734 0.4282
Loa Loa (eye worm) hypothetical protein 0.0098 0.0508 0.0739
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0046 0.0191 0.0278
Echinococcus granulosus sex peptide receptor 0.0023 0.0053 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0653 0.095
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0134 0.0212
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0758 0.1104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Leishmania major fatty acid transporter protein-like protein 0.1033 0.6224 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0627 0.3741 0.5448
Entamoeba histolytica hypothetical protein 0.0048 0.0202 0.1226
Onchocerca volvulus 0.0023 0.0053 0.0083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0372 0.6707
Schistosoma mansoni coup transcription factor 0.0021 0.0037 0.005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0679 0.0678
Toxoplasma gondii peptidylprolyl isomerase 0.0098 0.0511 0.5522
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0043
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0372 0.6707
Echinococcus multilocularis phd:f box containing protein 0.0019 0.003 0.0029
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0079 0.0476
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0053 0.0077
Brugia malayi Calcitonin receptor-like protein seb-1 0.0323 0.1884 0.2742
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0145
Echinococcus multilocularis Smad4 0.0016 0.001 0.001
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0046 0.0195 0.0262
Onchocerca volvulus 0.0023 0.0053 0.0083
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0079 0.1414
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0194 0.0304
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0511 0.0808
Schistosoma mansoni glutaminase 0.0556 0.3312 0.446
Echinococcus granulosus fmrfamide receptor 0.0023 0.0053 0.0071
Brugia malayi Serotonin receptor 0.0023 0.0053 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0031 0.0091
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.1072 0.1442
Brugia malayi Cytochrome P450 family protein 0.0027 0.0074 0.0107
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0053 0.0071
Schistosoma mansoni importin beta-1 0.0059 0.027 0.0364
Brugia malayi mbt repeat family protein 0.0046 0.0194 0.0282
Echinococcus granulosus neuropeptide s receptor 0.0023 0.0053 0.0071
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Schistosoma mansoni hypothetical protein 0.0587 0.3501 0.4714
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.004 0.0053
Echinococcus granulosus sentrin specific protease 1 0.0046 0.0195 0.0261
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0037 0.0049
Echinococcus granulosus importin subunit beta 1 0.0059 0.027 0.0363
Echinococcus granulosus expressed protein 0.01 0.0525 0.0706
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0053 0.0053
Mycobacterium ulcerans hypothetical protein 0.0121 0.0653 0.095
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0037 0.0053
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.001 0.0013
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus granulosus orexin receptor type 2 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0088 0.0117
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0037 0.005
Schistosoma mansoni 6-phosphofructokinase 0.0098 0.0508 0.0684
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.01 0.0525 0.0764
Onchocerca volvulus 0.0062 0.0291 0.0456
Brugia malayi G-protein coupled receptor 0.0023 0.0053 0.0077
Onchocerca volvulus 0.0023 0.0053 0.0083
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1938 0.1938
Brugia malayi mbt repeat family protein 0.0046 0.0194 0.0282
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0278 0.3008
Onchocerca volvulus 0.006 0.0277 0.0433
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0098 0.0511 0.922
Trypanosoma brucei glucosidase, putative 0.0074 0.0361 0.6517
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0653 0.3967
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1138 0.6867 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.0236
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0031 0.01 0.0145
Brugia malayi hypothetical protein 0.0075 0.0372 0.054
Giardia lamblia PHD finger protein 15 0.006 0.0278 0.1689
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1646 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0277 0.0373
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0653 0.1048
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.003 0.0093 0.0135
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.0236
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0758 0.1218
Onchocerca volvulus 0.0086 0.0439 0.0687
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Echinococcus granulosus GPCR family 2 0.0102 0.0535 0.072
Brugia malayi hypothetical protein 0.1059 0.6384 0.9296
Schistosoma mansoni lipoxygenase 0.0126 0.0679 0.0914
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0053 0.0071
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0053 0.0053
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0403 0.0541
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0003
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0361 0.0579
Onchocerca volvulus 0.0036 0.0134 0.0209
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0053 0.0053
Schistosoma mansoni opsin-like receptor 0.0023 0.0053 0.0072
Brugia malayi beta-lactamase family protein 0.0036 0.0134 0.0194
Schistosoma mansoni neuropeptide receptor 0.0023 0.0053 0.0072
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0105 0.0554 0.0889
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.011 0.0584 0.085
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0105 0.0554 0.0876
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0361 0.0571
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0088 0.0087
Schistosoma mansoni methyltransferase-related 0.0015 0.0002 0.0003
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.001 0.001
Brugia malayi 6-phosphofructokinase 0.0098 0.0508 0.0739
Mycobacterium ulcerans aldehyde dehydrogenase 0.0024 0.0056 0.0081
Brugia malayi putative neuropeptide receptor 0.0023 0.0053 0.0077
Brugia malayi Methyltransferase-like protein 4 0.0015 0.0002 0.0003
Schistosoma mansoni ran 0.0043 0.0175 0.0236
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.003 0.0046
Loa Loa (eye worm) phosphofructokinase 0.0098 0.0508 0.0739
Echinococcus multilocularis RUN 0.0021 0.004 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0361 0.1089
Onchocerca volvulus 0.0023 0.0053 0.0083
Schistosoma mansoni biogenic amine receptor 0.0023 0.0053 0.0072
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0015 0.0004 0.0006
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0554 0.0889
Echinococcus multilocularis microtubule associated protein 2 0.0735 0.4402 0.4402
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0461 0.062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Onchocerca volvulus 0.0023 0.0053 0.0083
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.003 0.0039
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.0924 1
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Loa Loa (eye worm) fatty acid synthase 0.0049 0.0209 0.0304
Brugia malayi RNA, U transporter 1 0.0167 0.0931 0.1356
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0037 0.0053
Echinococcus granulosus cpg binding protein 0.0091 0.0469 0.0631
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Mycobacterium tuberculosis Possible toxin MazF5 0.0133 0.0723 0.116
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0037 0.005
Echinococcus granulosus neuropeptide receptor A26 0.0023 0.0053 0.0071
Schistosoma mansoni microtubule-associated protein tau 0.0735 0.4402 0.5927
Mycobacterium ulcerans aldehyde dehydrogenase 0.0024 0.0056 0.0081
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0036 0.0134 0.0134
Echinococcus granulosus hypothetical protein 0.0023 0.0053 0.0071
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0017 0.0016 0.0046
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0175 0.0277
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0031 0.0091
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0361 0.1089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0053 0.0232 0.0337
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0063 0.1136
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.011 0.0584 0.085
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0036 0.0134 0.0813
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0525 0.1584
Mycobacterium ulcerans thioesterase 0.0041 0.0163 0.0237
Schistosoma mansoni lipoxygenase 0.0088 0.0448 0.0603
Echinococcus granulosus dnaJ subfamily B 0.123 0.7427 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0098 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0037 0.0053
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0361 0.2192
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0017 0.0015 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0653 0.1048
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0026 0.0073 0.0438
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0175 0.0254
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0134 0.0194
Trichomonas vaginalis phosphofructokinase, putative 0.0098 0.0508 0.1533
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Brugia malayi Latrophilin receptor protein 2 0.0102 0.0535 0.0779
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0037
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0023 0.0049 0.0048
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.004 0.0154 0.0247
Leishmania major importin beta-1 subunit, putative 0.0048 0.0202 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0098 0.0156
Echinococcus multilocularis neuropeptide s receptor 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0024 0.0056 0.009
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.004 0.0053
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0037 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Schistosoma mansoni survival motor neuron protein 0.0062 0.0291 0.0392
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0037 0.0057
Mycobacterium ulcerans thioesterase TesA 0.0041 0.0163 0.0237
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0105 0.0554 0.0806
Treponema pallidum exodeoxyribonuclease (exoA) 0.0036 0.0134 0.0813
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0037 0.0053
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0053 0.0071
Mycobacterium tuberculosis Toxin MazF2 0.0133 0.0723 0.116
Loa Loa (eye worm) hypothetical protein 0.0046 0.0194 0.0282
Brugia malayi Serotonin receptor 0.0023 0.0053 0.0077
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0079 0.0124
Loa Loa (eye worm) RNA binding protein 0.0188 0.1059 0.1541
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0053 0.0071
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0105 0.0554 0.0876
Echinococcus granulosus muscleblind protein 0.0457 0.2703 0.3638
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0031 0.0186
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0134 0.0403
Echinococcus granulosus g protein coupled receptor 0.0023 0.0053 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0037 0.0053
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0017 0.0016 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0151 0.0836 0.1217
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0079 0.0236
Loa Loa (eye worm) hypothetical protein 0.0046 0.0195 0.0283
Brugia malayi 6-phosphofructokinase 0.0098 0.0508 0.0739
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0037 0.005
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.027 0.2918
Brugia malayi CXXC zinc finger family protein 0.0086 0.0439 0.0639
Schistosoma mansoni adenoreceptor 0.0023 0.0053 0.0072
Echinococcus granulosus lysosomal alpha glucosidase 0.0332 0.1938 0.2609
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0091 0.0464 0.0745
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0037 0.0053
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.003 0.0029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0055 0.0074
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0053 0.0072
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0511 0.0808
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.002 0.0031 0.0044
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0053 0.0232 0.0372
Brugia malayi AKH receptor 0.0023 0.0053 0.0077
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0105 0.0554 0.3363
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0116
Echinococcus granulosus g protein coupled receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) glutaminase 0.0556 0.3312 0.4823
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0005 0.0081
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0033 0.0111 0.0161
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0049
Toxoplasma gondii proteasome regulatory subunit 0.0023 0.0049 0.0523
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0233 0.0314
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0361 0.1089
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0053 0.0053
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0361 0.1089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0079 0.0236
Brugia malayi jmjC domain containing protein 0.0019 0.003 0.0043
Brugia malayi jmjC domain containing protein 0.0019 0.003 0.0043
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0233 0.0233
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0361 0.0571
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0079 0.0126
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1048 0.6314 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Loa Loa (eye worm) 6-phosphofructokinase 0.0098 0.0508 0.0739
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.003 0.0316
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0105 0.0554 0.0806
Echinococcus granulosus snurportin 1 0.0627 0.3741 0.5037
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0372 0.4017
Onchocerca volvulus 0.0023 0.0053 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0653 0.1048
Plasmodium vivax SET domain protein, putative 0.006 0.0277 0.4999
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0036 0.0134 0.0212
Brugia malayi Dopamine receptor protein 1 0.0023 0.0053 0.0077
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0277 0.0372
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0134 0.0194
Mycobacterium ulcerans aldehyde dehydrogenase 0.0024 0.0056 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Entamoeba histolytica hypothetical protein 0.007 0.0338 0.2053
Schistosoma mansoni ap endonuclease 0.0036 0.0134 0.0181
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0134 0.0215
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.011 0.0584 0.085
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.003 0.0043
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.003 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0372 0.0588
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0023 0.0053 0.0072
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0105 0.0554 1
Leishmania major hypothetical protein, conserved 0.0036 0.0134 0.0215
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.0053 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0078 0.0386 0.0561
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0194 0.0262
Schistosoma mansoni hypothetical protein 0.0102 0.0535 0.0721
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0053 0.0077
Loa Loa (eye worm) 6-phosphofructokinase 0.0098 0.0508 0.0739
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0042 0.0167 0.0225
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0439 0.0639
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0048 0.0204 0.0327
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Schistosoma mansoni jumonji domain containing protein 0.0156 0.0866 0.1166
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0338 0.0455
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0053 0.0072
Schistosoma mansoni opsin-like receptor 0.0023 0.0053 0.0072
Brugia malayi hypothetical protein 0.007 0.0338 0.0492
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0017 0.0016 0.0021
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0134 0.2418
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0074 0.1323
Echinococcus multilocularis cpg binding protein 0.0091 0.0469 0.0469
Mycobacterium ulcerans polyketide synthase 0.0049 0.0213 0.031
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0049
Plasmodium vivax 6-phosphofructokinase, putative 0.0026 0.0073 0.1302
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0053 0.0071
Schistosoma mansoni rab6-interacting 0.0021 0.004 0.0053
Schistosoma mansoni hypothetical protein 0.0587 0.3501 0.4714
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0406 0.2393 0.3484
Schistosoma mansoni tar DNA-binding protein 0.0188 0.1059 0.1425
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0014
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.003 0.0039
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0036 0.0134 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0031 0.0091
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0386 0.0519
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.003 0.004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0005 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0073 0.0217
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0031 0.0098 0.1054
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0005 0.0007
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0053 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0105 0.0554 0.0806
Onchocerca volvulus 0.0023 0.0053 0.0083
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0653 0.095
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0074 0.0363 0.0582
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0511 0.31
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0134 0.0215
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0134 0.018
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.004 0.0039
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0053 0.0077
Echinococcus granulosus Smad4 0.0016 0.001 0.0013
Brugia malayi G-protein coupled receptor 0.0023 0.0053 0.0077
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0053 0.0072
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0023 0.0049 0.007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0037 0.0036
Echinococcus multilocularis smad 0.0016 0.001 0.001
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0032 0.0107 0.1156
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0068 0.0326 0.0523
Mycobacterium tuberculosis Conserved protein 0.0036 0.0134 0.0215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0461 0.0621
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0361 0.0361
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0017 0.0016 0.0046
Plasmodium falciparum importin beta, putative 0.0059 0.027 0.4871
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0036 0.0128 0.0205
Onchocerca volvulus 0.0023 0.0053 0.0083
Schistosoma mansoni histamine h1 receptor 0.0023 0.0053 0.0072
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0098 0.0508 0.0816
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0037 0.0049
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0079 0.0236
Brugia malayi Ets-domain containing protein 0.0046 0.0191 0.0278
Echinococcus granulosus AMP dependent ligase 0.002 0.0031 0.0041
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0014
Brugia malayi Protein kinase domain containing protein 0.0019 0.0026 0.0037
Entamoeba histolytica Ran family GTPase 0.0043 0.0175 0.1062
Loa Loa (eye worm) hypothetical protein 0.008 0.0403 0.0586
Onchocerca volvulus 0.0023 0.0053 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1033 0.6224 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0053 0.0072
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0102 0.0535 0.072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0653 0.1048
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium leprae Probable lipase LipE 0.0036 0.0134 0.0215
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Mycobacterium ulcerans acetyl-CoA synthetase 0.0105 0.0554 0.0806
Schistosoma mansoni tar DNA-binding protein 0.0188 0.1059 0.1425
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.004 0.0705
Plasmodium vivax 6-phosphofructokinase, putative 0.0026 0.0073 0.1302
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0046 0.0195 0.2101
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0053 0.0053
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0005 0.0007
Brugia malayi hypothetical protein 0.0305 0.1775 0.2584
Loa Loa (eye worm) hypothetical protein 0.0075 0.0372 0.054
Mycobacterium ulcerans lipase LipD 0.0036 0.0134 0.0194
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0017 0.0016 0.0094
Leishmania major hypothetical protein, conserved 0.0019 0.0026 0.0041
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0145
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0219
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0036 0.0134 0.0215
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0053 0.0072
Schistosoma mansoni hypothetical protein 0.0289 0.1677 0.2258
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0653 0.3967
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0053 0.0077
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0403 0.0586
Echinococcus granulosus tar DNA binding protein 0.0188 0.1059 0.1425
Schistosoma mansoni phd/f-box containing protein 0.0019 0.003 0.004
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0175 0.0175
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1048 0.6314 1
Echinococcus multilocularis expressed protein 0.01 0.0525 0.0524
Brugia malayi Pre-SET motif family protein 0.006 0.0277 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0134 0.0212
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.004 0.0154 0.0224
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi AF-10 protein 0.002 0.0031 0.0045
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0053 0.0072
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1033 0.6224 1
Mycobacterium tuberculosis Possible toxin MazF7 0.0133 0.0723 0.116
Plasmodium vivax hypothetical protein, conserved 0.006 0.0278 0.5021
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0175 0.1062
Echinococcus granulosus tissue type plasminogen activator 0.0019 0.0026 0.0034
Echinococcus multilocularis tar DNA binding protein 0.0188 0.1059 0.1058
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0049 0.0213 0.0342
Entamoeba histolytica phosphofructokinase, putative 0.0098 0.0508 0.3087
Echinococcus granulosus serotonin receptor 0.0023 0.0053 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0026 0.004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1938 0.1938
Mycobacterium ulcerans acyl-CoA synthetase 0.0105 0.0554 0.0806
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.1072 0.1071
Schistosoma mansoni FFA transport protein 0.1048 0.6314 0.8501
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0056 0.0076
Schistosoma mansoni hypothetical protein 0.0102 0.0535 0.0721
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0057
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0005 0.0004
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0053 0.0077
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0255 0.1468 0.1977
Loa Loa (eye worm) hypothetical protein 0.006 0.0277 0.0403
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0046 0.0195 0.0283
Brugia malayi RE15519p 0.0023 0.0053 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi Dopamine receptor 0.0023 0.0053 0.0077
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0194 0.0261
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.003 0.0039
Plasmodium falciparum cysteine repeat modular protein 1 0.0019 0.0026 0.0459
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0653 0.1048
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0105 0.0554 0.0889
Echinococcus granulosus peregrin 0.006 0.0278 0.0374
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0053 0.0053
Schistosoma mansoni protein phosphatase 2C 0.0019 0.003 0.004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0036 0.0134 0.0215
Brugia malayi beta-lactamase family protein 0.0036 0.0134 0.0194
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0049 0.0213 0.0342
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0053 0.0053
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0031 0.0555
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0046 0.0195 0.118
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0079 0.0124
Brugia malayi isocitrate dehydrogenase 0.0015 0.0005 0.0006
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0088 0.0127
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0005 0.0007
Loa Loa (eye worm) Smad1 0.0016 0.001 0.0014
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0118 0.0117
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0048 0.0204 0.0327
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0053 0.0071
Echinococcus multilocularis tissue type plasminogen activator 0.0019 0.0026 0.0025
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0053 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0053 0.0071
Schistosoma mansoni cpg binding protein 0.0091 0.0469 0.0632
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.001 0.0014
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.011 0.0584 0.0938
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0053 0.0072
Brugia malayi Smad1 0.0016 0.001 0.0014
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0053 0.0072
Mycobacterium tuberculosis Toxin MazF9 0.0133 0.0723 0.116
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0461 0.0621
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0194 0.0262
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0033 0.0111 0.0178
Brugia malayi sulfakinin receptor protein 0.0023 0.0053 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0037 0.0053
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.011 0.0584 0.085
Echinococcus granulosus allatostatin A receptor 0.0023 0.0053 0.0071
Entamoeba histolytica hypothetical protein 0.007 0.0338 0.2053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1646 0.4967
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0194 0.0261
Loa Loa (eye worm) hypothetical protein 0.0323 0.1884 0.2742
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0055 0.0055
Mycobacterium ulcerans hypothetical protein 0.0036 0.0134 0.0194
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0042 0.0167 0.0243
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0053 0.0071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0053 0.0053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0042 0.0167 0.0243
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Mycobacterium tuberculosis Conserved protein 0.0036 0.0134 0.0215
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0017 0.0016 0.0025
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0151 0.0836 0.1342
Loa Loa (eye worm) hypothetical protein 0.0457 0.2703 0.3935
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.004 0.0039
Leishmania major hypothetical protein, conserved 0.0019 0.003 0.0047
Onchocerca volvulus Fatty acid synthase homolog 0.0089 0.0456 0.0713
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0194
Schistosoma mansoni ets-related 0.0139 0.0762 0.1026
Loa Loa (eye worm) hypothetical protein 0.0053 0.0233 0.0339
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.01 0.0525 0.0764
Entamoeba histolytica hypothetical protein 0.007 0.0338 0.2053
Loa Loa (eye worm) MH2 domain-containing protein 0.0238 0.1365 0.1988
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0053 0.0077
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0005 0.0006
Onchocerca volvulus 0.0023 0.0053 0.0083
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.006 0.0059
Schistosoma mansoni polycystin 1-related 0.0021 0.004 0.0053
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0255 0.1468 0.1976
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0053 0.0072
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0457 0.2703 0.3935
Toxoplasma gondii exonuclease III APE 0.0036 0.0134 0.1448
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0037 0.005
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0026 0.0073 0.078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0061 0.0088
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0053 0.0071
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.008 0.0403 0.0542
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0046 0.0195 0.0586
Schistosoma mansoni cpg binding protein 0.0091 0.0469 0.0632
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0134 0.0181
Schistosoma mansoni apoptosis regulator bax 0.008 0.0403 0.0542
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0074 0.0116
Echinococcus multilocularis serotonin receptor 0.0023 0.0053 0.0053
Onchocerca volvulus 0.0021 0.0037 0.0057
Echinococcus multilocularis somatostatin receptor 0.0023 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0002 0.0005
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0053 0.0072
Leishmania major hypothetical protein, conserved 0.0075 0.0372 0.0596
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0134 0.0215
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0016 0.0006 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0277 0.0373
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0053 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0031 0.0091
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0015 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0023 0.0053 0.0072
Onchocerca volvulus 0.0021 0.004 0.0061
Brugia malayi Cytochrome P450 family protein 0.0027 0.0074 0.0107
Brugia malayi AMP-binding enzyme family protein 0.1138 0.6867 1
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0074 0.0107
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0338 0.0338
Schistosoma mansoni biogenic amine receptor 0.0023 0.0053 0.0072
Schistosoma mansoni hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0005 0.0004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0134 0.0134
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0037 0.0049
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.004 0.0039
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0323 0.1884 0.2742
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0037 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0019 0.0026 0.0037
Echinococcus multilocularis snurportin 1 0.0627 0.3741 0.3741
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0011 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0338 0.0455
Entamoeba histolytica phosphofructokinase, putative 0.0098 0.0508 0.3087
Loa Loa (eye worm) hypothetical protein 0.0121 0.0653 0.095
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0049 0.0213 0.031
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0068 0.0326 0.0523
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0121 0.0653 0.095
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.003 0.0046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0037 0.0036
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0005 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0461 0.0621
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0037 0.0049
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0017 0.0016 0.0278
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0175 0.3159
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0105 0.0554 0.0876
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0053 0.0072
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0026 0.0073 0.1302
Schistosoma mansoni amine GPCR 0.0023 0.0053 0.0072
Brugia malayi hypothetical protein 0.0049 0.0208 0.0303
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0043 0.0175 0.0236
Mycobacterium ulcerans polyketide synthase 0.0053 0.0232 0.0337
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0134 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0053 0.0072
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0141 0.0775 0.1244
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0053 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0037 0.0053
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0005 0.0007
Onchocerca volvulus 0.0023 0.0053 0.0083
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0361 0.0525
Schistosoma mansoni alpha-glucosidase 0.0285 0.1656 0.223
Leishmania major acetyl-CoA synthetase, putative 0.0105 0.0554 0.0889
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0372 0.0588
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0074 0.0107
Echinococcus granulosus lysine specific demethylase 5A 0.0078 0.0386 0.0519
Onchocerca volvulus 0.0192 0.1084 0.1697
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0024 0.0056 0.009
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0053 0.0071
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0197 0.1113 0.1113
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0053 0.0053
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0074 0.0116
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0053 0.0053
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0053 0.0072
Brugia malayi jmjC domain containing protein 0.0078 0.0386 0.0561
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0049 0.0213 0.031
Echinococcus multilocularis AMP dependent ligase 0.002 0.0031 0.0031
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.001 0.0014
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.011 0.0584 0.0938
Echinococcus granulosus smad 0.0016 0.001 0.0013
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.003 0.0043
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0053 0.0077
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.006 0.008
Loa Loa (eye worm) hypothetical protein 0.0105 0.0554 0.0806
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0005 0.0004
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0005 0.0081
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Brugia malayi hypothetical protein 0.0023 0.0053 0.0077
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0053 0.0077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0036 0.0134 0.0195
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1138 0.6867 1
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0134 0.0215
Echinococcus granulosus phd:f box containing protein 0.0019 0.003 0.0039
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0233 0.0314
Echinococcus granulosus microtubule associated protein 2 0.0735 0.4402 0.5927
Plasmodium falciparum sentrin-specific protease 1 0.0046 0.0195 0.3509
Mycobacterium ulcerans 6-phosphofructokinase 0.0098 0.0508 0.0739
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0026 0.0073 0.0438
Brugia malayi Muscleblind-like protein 0.0457 0.2703 0.3935
Leishmania major acetyl-CoA synthetase, putative 0.0105 0.0554 0.0889
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0141 0.0775 0.1128
Onchocerca volvulus 0.0105 0.0554 0.0867
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0758 0.1218
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0105 0.0554 0.0806
Brugia malayi ORL1-like opioid receptor 0.0023 0.0053 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0037 0.005
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0062 0.0291 0.0424
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0361 0.1089
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0278 0.3008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0037 0.0053
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0042 0.0167 0.0243
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0023 0.0049 0.007
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.003 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0037 0.005
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0049 0.0213 0.0342
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0016 0.0006 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0053 0.0053
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0422 0.0568
Loa Loa (eye worm) hypothetical protein 0.0305 0.1775 0.2584
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Toxin MazF3 0.0133 0.0723 0.116
Trichomonas vaginalis antibiotic synthetase, putative 0.0105 0.0554 0.167
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0053 0.0053
Toxoplasma gondii 6-phosphofructokinase 0.0026 0.0073 0.078
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trichomonas vaginalis glutaminase, putative 0.0556 0.3312 1
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0278 0.0374
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0037 0.0036
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0037 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0053 0.0071
Plasmodium vivax JmjC domain containing protein 0.0019 0.003 0.0528
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0077
Trichomonas vaginalis antibiotic synthetase, putative 0.0105 0.0554 0.167
Mycobacterium tuberculosis Possible toxin MazF1 0.0133 0.0723 0.116
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0005 0.0006
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0277 0.0277
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0053 0.0077
Brugia malayi neuropeptide F receptor 0.0023 0.0053 0.0077

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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