Detailed information for compound 136701

Basic information

Technical information
  • TDR Targets ID: 136701
  • Name: 2-[(4-chlorophenyl)sulfonyl-(2-methylpropyl)a mino]-N-hydroxyacetamide
  • MW: 320.792 | Formula: C12H17ClN2O4S
  • H donors: 2 H acceptors: 4 LogP: 1.88 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)CN(S(=O)(=O)c1ccc(cc1)Cl)CC(C)C
  • InChi: 1S/C12H17ClN2O4S/c1-9(2)7-15(8-12(16)14-17)20(18,19)11-5-3-10(13)4-6-11/h3-6,9,17H,7-8H2,1-2H3,(H,14,16)
  • InChiKey: KIVYTNANTFIVKL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-chlorophenyl)sulfonyl-isobutyl-amino]ethanehydroxamic acid
  • 2-[(4-chlorophenyl)sulfonyl-isobutylamino]ethanehydroxamic acid
  • 2-[(4-chlorophenyl)sulfonyl-(2-methylpropyl)amino]-N-hydroxy-ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens matrix metallopeptidase 3 (stromelysin 1, progelatinase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus matrix metallopeptidase 7 M10 family matrix metallopeptidase 3 (stromelysin 1, progelatinase) 477 aa 431 aa 34.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.01 0.0345
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0118 0.0118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0141 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0026 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0011 0.0041
Trichomonas vaginalis D-aminoacylase, putative 0.0157 0.0498 0.1772
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0011 0.0076
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0065 0.0165 0.0165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0011 0.0011
Onchocerca volvulus 0.0022 0.0011 0.0128
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0008 0.00000000056059
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0103 0.0302 0.0729
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0035 0.0035
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0027 0.0026 0.0375
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0718
Toxoplasma gondii exonuclease III APE 0.0065 0.0165 0.2492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Brugia malayi Pre-SET motif family protein 0.0227 0.0749 0.2755
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0065 0.0165 0.3207
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0086 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.01 0.0345
Schistosoma mansoni inositol monophosphatase 0.0115 0.0346 0.0346
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0082 0.0225 0.0225
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi hypothetical protein 0.0022 0.0011 0.0041
Echinococcus multilocularis microtubule associated protein 2 0.2786 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0187 0.0187
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.008 0.0295
Brugia malayi Hemopexin family protein 0.0037 0.0065 0.0239
Echinococcus multilocularis dna polymerase eta 0.0041 0.008 0.008
Echinococcus multilocularis ornithine aminotransferase 0.0113 0.0337 0.0337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0187 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0061
Giardia lamblia Hypothetical protein 0.0022 0.0011 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Schistosoma mansoni smad 0.0043 0.0086 0.0086
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0328 0.0803
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0113 0.0337 0.1239
Onchocerca volvulus Matrilysin homolog 0.0058 0.0141 0.1639
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0011 0.0024
Echinococcus multilocularis ornithine aminotransferase 0.0113 0.0337 0.0337
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0035 0.0035
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0011 0.0024
Loa Loa (eye worm) CXXC zinc finger family protein 0.0102 0.0297 0.1093
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Brugia malayi Latrophilin receptor protein 2 0.0244 0.0813 0.2988
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0113 0.0337 0.0828
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0045 0.0093 0.1973
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0064 0.0064
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0187 0.0187
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0047 0.01 0.189
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0026 0.0026
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Echinococcus granulosus expressed protein 0.0044 0.0088 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0013 0.0032
Brugia malayi Bromodomain containing protein 0.0039 0.0073 0.0268
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.008 0.008
Mycobacterium ulcerans hypothetical protein 0.0157 0.0498 0.1647
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0011 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0022 0.0011 0.0011
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0026 0.0078
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0244 0.0813 0.2988
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0027 0.0026 0.0026
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Schistosoma mansoni hypothetical protein 0.0047 0.0102 0.0102
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0048 0.0048
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0113 0.0337 0.106
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.008 0.0097
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0045 0.0093 0.1731
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0008 0.0008
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0065 0.0165 0.3207
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.008 0.0272
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.008 0.1474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0716
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0011 0.0011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0157 0.0498 0.0498
Loa Loa (eye worm) inositol-1 0.0115 0.0346 0.1271
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0027 0.0026 0.0026
Loa Loa (eye worm) latrophilin receptor protein 2 0.0244 0.0813 0.2988
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0204 0.0668 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0231 0.0812
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0022 0.0011 0.0011
Loa Loa (eye worm) fli-1 protein 0.0226 0.0746 0.2745
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Echinococcus multilocularis beta LACTamase domain containing family member 0.0157 0.0498 0.0498
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0112 0.0335 0.6664
Echinococcus multilocularis cpg binding protein 0.0109 0.0325 0.0325
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis penicillin-binding protein, putative 0.0157 0.0498 0.1772
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0244 0.0813 0.2988
Brugia malayi hypothetical protein 0.0082 0.0225 0.0828
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei trypanothione reductase 0.0048 0.0105 0.1974
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0718
Schistosoma mansoni hypothetical protein 0.0244 0.0813 0.0813
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.0772 0.2719 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0011 0.0011
Brugia malayi Thioredoxin reductase 0.0048 0.0105 0.0385
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Onchocerca volvulus Matrilysin homolog 0.0026 0.0025 0.0293
Schistosoma mansoni bromodomain containing protein 0.0071 0.0187 0.0187
Entamoeba histolytica hypothetical protein 0.0027 0.0026 0.0428
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0141 0.0438 0.0438
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.0749 0.2755
Schistosoma mansoni smad1 5 8 and 0.0043 0.0086 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0204 0.0668 0.0668
Loa Loa (eye worm) matrixin family protein 0.0064 0.016 0.0589
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0047 0.01 0.189
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0115 0.0346 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.008 0.1474
Brugia malayi glutathione reductase 0.0048 0.0105 0.0385
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0065 0.0165 0.3207
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni hypothetical protein 0.0527 0.1836 0.1836
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Treponema pallidum exodeoxyribonuclease (exoA) 0.0065 0.0165 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0438 0.1556
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0141 0.0438 0.0438
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0045 0.0093 0.0317
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0045 0.0093 0.1731
Echinococcus granulosus ferritin 0.0044 0.0088 0.0088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0204 0.0668 0.2459
Loa Loa (eye worm) beta-lactamase 0.0157 0.0498 0.1832
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0718
Brugia malayi Smad1 0.0043 0.0086 0.0318
Trichomonas vaginalis inositol monophosphatase, putative 0.0115 0.0346 0.1225
Schistosoma mansoni ferritin 0.0044 0.0088 0.0088
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0011 0.0011
Schistosoma mansoni cpg binding protein 0.0109 0.0325 0.0325
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0045 0.0093 0.1731
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0011 0.0011
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0113 0.0337 0.106
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0011 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Plasmodium falciparum ornithine aminotransferase 0.0113 0.0337 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0107 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0438 0.1556
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.01 0.0345
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0026 0.0026
Brugia malayi MH2 domain containing protein 0.0043 0.0086 0.0318
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0113 0.0337 0.5
Schistosoma mansoni smad1 5 8 and 0.0043 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0334 0.1183
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0022 0.0011 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0082 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0334 0.1183
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Echinococcus multilocularis expressed protein 0.0044 0.0088 0.0088
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0011 0.0076
Trypanosoma cruzi target of rapamycin kinase 3 0.0112 0.0335 0.6664
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0026 0.0026
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0011 0.0011
Leishmania major trypanothione reductase 0.0048 0.0105 0.1974
Schistosoma mansoni ferritin light chain 0.0044 0.0088 0.0088
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0022 0.0011 0.0011
Brugia malayi Inositol-1 0.0115 0.0346 0.1271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Onchocerca volvulus 0.0157 0.0498 0.5784
Mycobacterium ulcerans L-lysine aminotransferase 0.0113 0.0337 0.106
Loa Loa (eye worm) RNA binding protein 0.0071 0.0187 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0026 0.0078
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0011 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0527 0.1836 0.6755
Brugia malayi Fli-1 protein 0.0226 0.0746 0.2745
Trypanosoma brucei unspecified product 0.0029 0.0034 0.0525
Leishmania major phosphatidylinositol 3-kinase, putative 0.0047 0.01 0.189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0204 0.0668 0.0668
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0045 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0047 0.01 0.01
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Giardia lamblia DUB-1 0.0022 0.0011 0.0076
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0011 0.0052
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0022 0.0011 0.0011
Loa Loa (eye worm) Smad1 0.0043 0.0086 0.0318
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.068 0.2388 0.2388
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0113 0.0337 0.0828
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Leishmania major hypothetical protein, conserved 0.0157 0.0498 1
Toxoplasma gondii non-specific serine/threonine protein kinase 0.003 0.0037 0.0466
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0967 0.3427 0.3427
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0026
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Echinococcus granulosus dna polymerase kappa 0.0041 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Echinococcus granulosus dnaJ subfamily B 0.0967 0.3427 0.3427
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis expressed protein 0.0022 0.0011 0.0011
Mycobacterium tuberculosis Probable reductase 0.011 0.0328 0.0803
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0325 0.9642
Brugia malayi hypothetical protein 0.0071 0.0185 0.0681
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0007 0.0026
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0008 0.0029
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0328 0.1028
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Trichomonas vaginalis esterase, putative 0.0157 0.0498 0.1772
Schistosoma mansoni cpg binding protein 0.0109 0.0325 0.0325
Schistosoma mansoni inositol monophosphatase 0.0115 0.0346 0.0346
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0076
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0048 0.0048
Brugia malayi Matrixin family protein 0.0026 0.0025 0.0093
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Schistosoma mansoni survival motor neuron protein 0.0047 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0011 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0244 0.0813 0.0813
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0771 0.0771
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0716
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0157 0.0498 0.1287
Schistosoma mansoni apoferritin-2 0.0044 0.0088 0.0088
Schistosoma mansoni fkbp-rapamycin associated protein 0.0027 0.0026 0.0026
Schistosoma mansoni ferritin 0.0044 0.0088 0.0088
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0107 0.0107
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0027 0.0026 0.0428
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Mycobacterium ulcerans acetylornithine aminotransferase 0.0113 0.0337 0.106
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0065 0.0165 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi MH1 domain containing protein 0.0043 0.0086 0.0318
Onchocerca volvulus 0.0047 0.0102 0.1179
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0045 0.0093 0.0341
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Echinococcus multilocularis zinc finger protein 0.0026 0.0024 0.0024
Onchocerca volvulus 0.0022 0.0011 0.0128
Trichomonas vaginalis D-aminoacylase, putative 0.0157 0.0498 0.1772
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0011 0.0011
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0008 0.0008
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0199 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0054 0.0054
Echinococcus multilocularis dnaJ subfamily B 0.0967 0.3427 0.3427
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0011 0.0024
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.008 0.0272
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Plasmodium falciparum glutathione reductase 0.0048 0.0105 0.2942
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.008 0.1474
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0115 0.0346 0.7852
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0045 0.0093 0.258
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0093
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0328 0.0803
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0141 0.0438 0.8775
Mycobacterium tuberculosis Probable aminotransferase 0.0791 0.2791 0.7814
Schistosoma mansoni smad1 5 8 and 0.0043 0.0086 0.0086
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0011 0.0099
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0054 0.0054
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0113 0.0337 0.5215
Mycobacterium leprae conserved hypothetical protein 0.0157 0.0498 0.1647
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0047 0.01 0.01
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0026 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Echinococcus granulosus ubiquitin specific peptidase c family 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0093
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0011 0.0011
Onchocerca volvulus 0.0037 0.0065 0.0755
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0011 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0066 0.0223
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0244 0.0813 0.0813
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0064 0.0064
Plasmodium vivax glutathione reductase, putative 0.0048 0.0105 0.1921
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0034 0.0525
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.01 0.037
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0022 0.0011 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Mycobacterium tuberculosis Probable lipase LipE 0.0157 0.0498 0.1287
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) transcription factor SMAD2 0.0635 0.2224 0.818
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0791 0.2791 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0065 0.0165 0.3003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Echinococcus multilocularis inositol monophosphatase 1 0.0115 0.0346 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.01 0.0345
Echinococcus granulosus GPCR family 2 0.0244 0.0813 0.0813
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Plasmodium vivax SET domain protein, putative 0.0034 0.0054 0.0891
Echinococcus multilocularis tumor protein p63 0.1073 0.3809 0.3809
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0065 0.0165 0.3654
Leishmania major DNA polymerase eta, putative 0.0041 0.008 0.1474
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0011 0.0011
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0157 0.0498 0.1647
Mycobacterium ulcerans hypothetical protein 0.0791 0.2791 1
Echinococcus granulosus cpg binding protein 0.0109 0.0325 0.0325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0045 0.0093 0.0317
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni ferritin light chain 0.0044 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0105 0.0385
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0045 0.0093 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Conserved protein 0.0157 0.0498 0.1287
Loa Loa (eye worm) hypothetical protein 0.005 0.011 0.0405
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0026 0.0096
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Conserved protein 0.0157 0.0498 0.1287
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.0054 0.0197
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0061
Loa Loa (eye worm) histone methyltransferase 0.0033 0.0048 0.0177
Loa Loa (eye worm) hypothetical protein 0.0109 0.0325 0.1195
Toxoplasma gondii histone lysine methyltransferase SET1 0.0196 0.0639 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0105 0.0167
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0346 0.689
Schistosoma mansoni hypothetical protein 0.0082 0.0225 0.0225
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Brugia malayi Ets-domain containing protein 0.0074 0.0199 0.0732
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0187 0.0688
Onchocerca volvulus 0.0258 0.0861 1
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0105 0.1974
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trichomonas vaginalis D-aminoacylase, putative 0.0157 0.0498 0.1772
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Brugia malayi MH2 domain containing protein 0.0635 0.2224 0.818
Schistosoma mansoni hypothetical protein 0.0037 0.0065 0.0065
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0022 0.0011 0.0011
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0032 0.0046 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0325 0.647
Schistosoma mansoni peptidase 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0772 0.2719 1
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Leishmania major DNA polymerase kappa, putative 0.0041 0.008 0.1474
Plasmodium vivax ataxin-2 like protein, putative 0.0109 0.0325 0.6446
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0204 0.0668 0.0668
Echinococcus granulosus Aminotransferase class III 0.0113 0.0337 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.0234 0.0823
Brugia malayi Pre-SET motif family protein 0.0034 0.0054 0.02
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.01 0.037
Trypanosoma brucei unspecified product 0.0029 0.0034 0.0525
Plasmodium falciparum thioredoxin reductase 0.0048 0.0105 0.2942
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma brucei PAB1-binding protein , putative 0.0109 0.0325 0.647
Brugia malayi PHD-finger family protein 0.0031 0.0044 0.0162
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0021 0.0004 0.0004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0065 0.0165 0.3654
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0022 0.0011 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0157 0.0498 1
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0011 0.0011
Toxoplasma gondii hypothetical protein 0.0022 0.0011 0.0052
Onchocerca volvulus 0.0102 0.0297 0.3452
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0044 0.0088 0.0151
Entamoeba histolytica hypothetical protein 0.0082 0.0225 0.5049
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0026 0.0292
Toxoplasma gondii thioredoxin reductase 0.0048 0.0105 0.1534
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0022 0.0011 0.0011
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0141 0.0438 0.8775
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Onchocerca volvulus 0.0022 0.0011 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0174 0.0174
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.068 0.2388 0.2388
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Echinococcus granulosus ornithine aminotransferase 0.0113 0.0337 0.0337
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0011 0.0041
Schistosoma mansoni ferritin 0.0044 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0244 0.0813 0.0813
Onchocerca volvulus 0.017 0.0544 0.632
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1831
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0791 0.2791 0.7814
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0204 0.0668 0.0668
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0141 0.0438 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0113 0.0337 0.0337
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0141 0.0438 0.8775
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0346 0.689
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0334 0.1183
Brugia malayi Matrixin family protein 0.0026 0.0025 0.0093
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0066 0.017 0.3315
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0791 0.2791 1
Entamoeba histolytica hypothetical protein 0.0082 0.0225 0.5049
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0118 0.0118
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0086 0.0086
Trypanosoma brucei unspecified product 0.0041 0.008 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0113 0.0337 0.106
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0011 0.0011
Onchocerca volvulus 0.0157 0.0498 0.5783
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0021 0.0004 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0157 0.0498 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0052 0.0118 0.0434
Onchocerca volvulus 0.0157 0.0498 0.5784
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis ap endonuclease, putative 0.0065 0.0165 0.0576
Schistosoma mansoni hypothetical protein 0.0244 0.0813 0.0813
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0008 0.0012
Schistosoma mansoni gabp alpha 0.0074 0.0199 0.0199
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.0141 0.2719
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni apoferritin-2 0.0044 0.0088 0.0088
Onchocerca volvulus 0.0157 0.0498 0.5784
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0013 0.0032
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0011 0.0011
Echinococcus multilocularis ferritin 0.0044 0.0088 0.0088
Schistosoma mansoni Smad4 0.0043 0.0086 0.0086
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0346 0.1225
Schistosoma mansoni DNA helicase recq1 0.0021 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Trichomonas vaginalis ferritin, putative 0.0044 0.0088 0.0298
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0045 0.0093 0.0341
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Toxoplasma gondii ABC1 family protein 0.0157 0.0498 0.7771
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Echinococcus granulosus Smad4 0.0043 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0244 0.0813 0.0813
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0026 0.0375
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0373 0.093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus tumor protein p63 0.1073 0.3809 0.3809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0011 0.0011
Mycobacterium ulcerans bacterioferritin BfrA 0.0044 0.0088 0.0151
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0271 0.0956
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0217 0.0713 0.0713
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0113 0.0337 0.0828
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.173 0.6185 0.6185
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0346 0.1225
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0269
Brugia malayi CXXC zinc finger family protein 0.0102 0.0297 0.1093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0157 0.0498 0.1832
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0771 0.0771
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0073 0.0194 0.0713
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0187 0.0187
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0054 0.0054
Brugia malayi TAR-binding protein 0.0071 0.0187 0.0688
Echinococcus multilocularis Aminotransferase class III 0.0113 0.0337 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0035 0.0035
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0011 0.0099
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0325 0.9642
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.0011 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0118 0.0118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0011 0.0076
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0113 0.0337 0.106
Echinococcus granulosus inositol monophosphatase 1 0.0115 0.0346 0.0346
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0011 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0026 0.0026
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus multilocularis ubiquitin specific protease 41 0.0022 0.0011 0.0011
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0065 0.0165 0.3207
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0187 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Mycobacterium ulcerans beta-lactamase 0.0157 0.0498 0.1647
Entamoeba histolytica hypothetical protein 0.0082 0.0225 0.5049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0718
Loa Loa (eye worm) matrixin family protein 0.0058 0.0141 0.0519
Echinococcus granulosus dna polymerase eta 0.0041 0.008 0.008
Onchocerca volvulus 0.0034 0.0054 0.0633
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0346 0.689
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Echinococcus granulosus smad 0.0043 0.0086 0.0086
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0373 0.119
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0011 0.0011
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0105 0.1921
Brugia malayi exodeoxyribonuclease III family protein 0.0065 0.0165 0.0607
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.012 0.0364 0.129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.008 0.0097
Loa Loa (eye worm) phosphatidylinositol 3 0.0141 0.0438 0.1611
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.008 0.168
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0103 0.0302 0.0933
Brugia malayi Matrixin family protein 0.0026 0.0025 0.0093
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Brugia malayi RNA binding protein 0.0071 0.0187 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0026 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0034 0.0525
Schistosoma mansoni ap endonuclease 0.0065 0.0165 0.0165
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0008 0.0012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0011 0.0011
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0105 0.0105
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0011 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Giardia lamblia GTOR 0.0141 0.0438 1
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0011 0.0099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0157 0.0498 0.0498
Brugia malayi MH1 domain containing protein 0.0043 0.0086 0.0318
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0157 0.0498 0.1832
Schistosoma mansoni cellular tumor antigen P53 0.0157 0.0498 0.0498
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium ulcerans lipase LipD 0.0157 0.0498 0.1647
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0011 0.0024
Toxoplasma gondii LsmAD domain-containing protein 0.0109 0.0325 0.5028
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0113 0.0337 0.106
Echinococcus granulosus ubiquitin specific protease 41 0.0022 0.0011 0.0011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Toxoplasma gondii ubiquitin-specific protease USP4 0.0022 0.0011 0.0052
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0772 0.2719 1
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.017 0.0544 0.2002
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.008 0.1474
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0328 0.0803
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Entamoeba histolytica protein kinase rad3, putative 0.0027 0.0026 0.0428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0204 0.0668 0.2459
Giardia lamblia DINP protein human, muc B family 0.0041 0.008 0.168
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0045 0.0093 0.1731
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus zinc finger protein 0.0026 0.0024 0.0024
Loa Loa (eye worm) matrix metalloproteinase 0.0026 0.0025 0.0093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0233 0.0771 0.2834
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0141 0.0438 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0065 0.0165 0.0607
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0115 0.0346 0.1092
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0174 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0037 0.0118
Trichomonas vaginalis helicase, putative 0.0023 0.0013 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0187 0.0688
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0022 0.0011 0.0011
Loa Loa (eye worm) RecQ helicase 0.0021 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0244 0.0813 0.0813
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni DNA polymerase eta 0.0041 0.008 0.008
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.008 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Probable hydrolase 0.0157 0.0498 0.1287
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0022 0.0011 0.0011
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.0438 0.1556
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0199 0.0732
Echinococcus granulosus tar DNA binding protein 0.0071 0.0187 0.0187
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus granulosus bloom syndrome protein 0.0021 0.0008 0.0008
Schistosoma mansoni ap endonuclease 0.0065 0.0165 0.0165
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0112 0.0335 0.6664
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0096 0.0276 0.0276
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0011 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0022 0.0011 0.0011
Loa Loa (eye worm) nuclear factor I 0.0024 0.0017 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0157 0.0498 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni zinc finger protein 0.0026 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0011 0.0024
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0086 0.0086
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0011 0.0011
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.008 0.0295
Leishmania major hypothetical protein, conserved 0.0109 0.0325 0.647
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.008 0.008
Trichomonas vaginalis set domain proteins, putative 0.0258 0.0861 0.3075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0231 0.0812
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0118 0.0118
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0008 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0011 0.0041
Brugia malayi ubiquitin specific protease 14 0.0022 0.0011 0.0041
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0373 0.093
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.0234 0.0823
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0045 0.0093 0.1345
Echinococcus granulosus beta LACTamase domain containing family member 0.0157 0.0498 0.0498
Schistosoma mansoni ets-related 0.0226 0.0746 0.0746
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0047 0.01 0.189
Brugia malayi hypothetical protein 0.0233 0.0771 0.2834
Brugia malayi FAT domain containing protein 0.0021 0.0004 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0204 0.0668 0.0668
Brugia malayi latrophilin 2 splice variant baaae 0.0527 0.1836 0.6755
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.008 0.1474
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0187 0.0688
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0011 0.0099
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0199 0.0199
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0011 0.0041
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0047 0.01 0.01
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0054 0.074
Loa Loa (eye worm) hypothetical protein 0.0041 0.008 0.0295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0065 0.0165 0.0576
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0026
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0328 0.0803
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0137
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0011 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0187 0.0187
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0044 0.0088 0.0118
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0346 0.689
Mycobacterium tuberculosis Probable lipase LipD 0.0157 0.0498 0.1287
Brugia malayi beta-lactamase family protein 0.0157 0.0498 0.1832
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0008 0.0029
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0157 0.0498 0.1287
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0011 0.0011
Schistosoma mansoni DNA helicase recq5 0.0021 0.0008 0.0008
Schistosoma mansoni microtubule-associated protein tau 0.2786 1 1
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.008 0.1474
Mycobacterium ulcerans esterase/lipase LipP 0.0157 0.0498 0.1647
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.008 0.1474
Brugia malayi hypothetical protein 0.017 0.0544 0.2002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0022 0.0011 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0105 0.0105
Mycobacterium tuberculosis Conserved protein 0.0157 0.0498 0.1287
Trichomonas vaginalis penicillin-binding protein, putative 0.0157 0.0498 0.1772
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi Ets-domain containing protein 0.0074 0.0199 0.0732
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.008 0.1474
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0065 0.0165 0.3161
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0047 0.01 0.189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Onchocerca volvulus Matrix metalloproteinase homolog 0.0058 0.0141 0.1639
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0082 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0124
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0102 0.0374
Brugia malayi Matrixin family protein 0.0026 0.0025 0.0093
Echinococcus multilocularis dna polymerase kappa 0.0041 0.008 0.008
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.008 0.0295
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0113 0.0337 0.106
Loa Loa (eye worm) hypothetical protein 0.0032 0.0046 0.0169
Brugia malayi Bromodomain containing protein 0.0083 0.0231 0.0848
Echinococcus multilocularis GPCR, family 2 0.0244 0.0813 0.0813
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Loa Loa (eye worm) glutathione reductase 0.0048 0.0105 0.0385
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0204 0.0668 0.0668
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0044 0.0088 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0204 0.0716
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0325 0.647
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0061
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0008 0.0029
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0157 0.0498 0.1832
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0115 0.0346 0.5354
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0086 0.0086
Mycobacterium leprae Probable lipase LipE 0.0157 0.0498 0.1647
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0141 0.0438 0.8775
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0011 0.0011
Brugia malayi MH2 domain containing protein 0.0043 0.0086 0.0318
Mycobacterium tuberculosis Probable esterase LipL 0.0157 0.0498 0.1287
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0113 0.0337 0.106
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0334 0.1183
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0065 0.0165 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0334 0.1183
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0011 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi hypothetical protein 0.0109 0.0325 0.1195
Entamoeba histolytica hypothetical protein 0.0022 0.0011 0.0076
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0086 0.0086
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0011 0.0066
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0011 0.0011
Schistosoma mansoni cpg binding protein 0.0102 0.0297 0.0297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.01 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0086 0.0318
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.008 0.0124
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.008 0.1474
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0008 0.0008
Schistosoma mansoni ferritin 0.0044 0.0088 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0308 0.1089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Onchocerca volvulus 0.0026 0.0025 0.0293
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0011 0.0011
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0141 0.0438 0.8775
Schistosoma mansoni hypothetical protein 0.0049 0.0107 0.0107
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0772 0.2719 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Brugia malayi Matrixin family protein 0.0064 0.016 0.0589
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0011 0.0076
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0086 0.0318
Echinococcus multilocularis smad 0.0043 0.0086 0.0086
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0157 0.0498 0.1287
Brugia malayi beta-lactamase family protein 0.0157 0.0498 0.1832
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0011 0.0052
Loa Loa (eye worm) hypothetical protein 0.0064 0.016 0.0589
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0011 0.0066
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0328 0.0803
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Plasmodium vivax ornithine aminotransferase, putative 0.0113 0.0337 0.6689
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0011 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0244 0.0813 0.0813
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0113 0.0337 0.9659
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0045 0.0093 0.0093
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0096 0.0276 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.026 0.0917
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0045 0.0093 0.1676
Trypanosoma cruzi hypothetical protein, conserved 0.0157 0.0498 1
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0113 0.0337 0.0828
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0032
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0099
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0052
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0045 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Schistosoma mansoni hypothetical protein 0.0022 0.0011 0.0011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0011 0.0076
Loa Loa (eye worm) MH2 domain-containing protein 0.0635 0.2224 0.818
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.0234 0.0823
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0045 0.0093 0.0341
Loa Loa (eye worm) hypothetical protein 0.0042 0.0082 0.0302
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0011 0.0066
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0141 0.0438 0.8775
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0047 0.01 0.189
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0438 0.1611
Echinococcus multilocularis Smad4 0.0043 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0065 0.0165 0.4779
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0373 0.093
Brugia malayi beta-lactamase 0.0157 0.0498 0.1832
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0013 0.0032
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0011 0.0041
Entamoeba histolytica hypothetical protein 0.0082 0.0225 0.5049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Mycobacterium ulcerans bacterioferritin BfrB 0.0044 0.0088 0.0151
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0065 0.0165 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1004 0.3559 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0011 0.0011
Toxoplasma gondii target of rapamycin (TOR), putative 0.0105 0.0308 0.4756
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0026 0.0375
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0011 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0034 0.0525
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0791 0.2791 1

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 68 % Inhibitory activity against mouse macrophage metalloelastase (MME) at 100 nM concentration using [3H]-Elastin as a substrate ChEMBL. 9871508
Inhibition (binding) = 68 % Inhibitory activity against mouse macrophage metalloelastase (MME) at 100 nM concentration using [3H]-Elastin as a substrate ChEMBL. 9871508
Ki (binding) = 6.03 Inhibition of human recombinant MMP3 ChEMBL. 17275314
Ki (binding) = 0.943 uM Inhibition activity against recombinant human stromelysin (Matrix metalloproteinase-3) ChEMBL. 9258358
Ki (binding) = 0.943 uM Inhibition activity against recombinant human stromelysin (Matrix metalloproteinase-3) ChEMBL. 9258358
log(1/Ki) (binding) = 6.03 Inhibition of human recombinant MMP3 ChEMBL. 17275314

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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