Detailed information for compound 1479309

Basic information

Technical information
  • TDR Targets ID: 1479309
  • Name: 4-[5-[(4-ethylphenyl)amino]-3-methyl-1,3,4-th iadiazol-3-ium-2-yl]benzoic acid
  • MW: 340.419 | Formula: C18H18N3O2S+
  • H donors: 2 H acceptors: 3 LogP: 4.94 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)Nc1sc([n+](n1)C)c1ccc(cc1)C(=O)O
  • InChi: 1S/C18H17N3O2S/c1-3-12-4-10-15(11-5-12)19-18-20-21(2)16(24-18)13-6-8-14(9-7-13)17(22)23/h4-11H,3H2,1-2H3,(H-,19,20,22,23)/p+1
  • InChiKey: SVBFNFGWGBJMCY-UHFFFAOYSA-O  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0007 0.0001 0.0003
Echinococcus granulosus FACT complex subunit SPT16 0.0017 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.0287 0.0117 0.0328
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0012 0.0033
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0043 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.001
Brugia malayi hypothetical protein 0.0009 0.0002 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0001 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0287 0.0117 0.0117
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0046 0.0017 0.0436
Toxoplasma gondii peptidase D, putative 0.0043 0.0016 0.0045
Echinococcus granulosus neuropeptide FF receptor 2 0.0287 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Schistosoma mansoni myosin xvIII 0.0287 0.0117 0.0328
Echinococcus multilocularis lamin 0.0028 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0004
Brugia malayi Methionine aminopeptidase protein type I 0.0017 0.0005 0.0014
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0953 0.0393 0.1102
Echinococcus multilocularis g-protein coupled receptor 0.0287 0.0117 0.0117
Echinococcus granulosus methionyl aminopeptidase 2 0.0017 0.0005 0.0005
Echinococcus granulosus orexin receptor type 2 0.0287 0.0117 0.0117
Trichomonas vaginalis rotamase, putative 0.0034 0.0012 0.0303
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0007 0.0001 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0001 0.0001
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0017 0.0005 0.0014
Onchocerca volvulus 0.0287 0.0117 0.0328
Echinococcus multilocularis somatostatin receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0001 0.0001
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.8615 0.3568 1
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0017 0.0005 0.0014
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0287 0.0117 0.0328
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0017 0.0048
Onchocerca volvulus 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Echinococcus multilocularis Dipeptidyl peptidase 9 0.1134 0.0468 0.0468
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.8615 0.3568 1
Schistosoma mansoni ap endonuclease 0.0019 0.0006 0.0017
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0016 0.0044
Onchocerca volvulus 0.0287 0.0117 0.0328
Schistosoma mansoni DNA helicase recq1 0.0009 0.0002 0.0005
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0007 0.0001 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0005 0.0013
Entamoeba histolytica Xaa-Pro dipeptidase, putative 0.0043 0.0016 0.0407
Trypanosoma brucei Metallopeptidase family M24, putative 0.0017 0.0005 0.0014
Trypanosoma cruzi Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0181 0.0073 0.0204
Echinococcus multilocularis xaa Pro dipeptidase 0.0043 0.0016 0.0016
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.0001 0.0007
Brugia malayi Protein kinase domain containing protein 0.0015 0.0004 0.0011
Echinococcus multilocularis methionyl aminopeptidase 2 0.0017 0.0005 0.0005
Trypanosoma cruzi oligopeptidase b 0.3459 0.1432 0.4012
Plasmodium falciparum methionine aminopeptidase 1c, putative 0.0017 0.0005 0.0126
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0006 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0017 0.0005 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0007 0.0001 0.0003
Schistosoma mansoni opsin-like receptor 0.0287 0.0117 0.0328
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Plasmodium vivax FACT complex subunit SPT16, putative 0.0017 0.0005 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0024 0.0067
Mycobacterium tuberculosis Probable peptidase 0.3459 0.1432 0.4512
Mycobacterium tuberculosis Probable cytoplasmic peptidase PepQ 0.0098 0.0039 0.0121
Brugia malayi Cytochrome P450 family protein 0.0007 0.0001 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0287 0.0117 0.0328
Loa Loa (eye worm) G-protein coupled receptor 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Brugia malayi cytosol aminopeptidase 0.0043 0.0016 0.0044
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0006 0.0152
Loa Loa (eye worm) TYRA-2 protein 0.0287 0.0117 0.0328
Toxoplasma gondii methionine aminopeptidase 0.0017 0.0005 0.0014
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0287 0.0117 0.0328
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0003 0.0002
Echinococcus granulosus xaa pro aminopeptidase 0.0156 0.0063 0.0062
Echinococcus granulosus neuropeptides capa receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis leucine aminopeptidase protein 0.0363 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0329 0.0134 0.0376
Schistosoma mansoni biogenic amine receptor 0.0287 0.0117 0.0328
Brugia malayi AKH receptor 0.0287 0.0117 0.0328
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.1134 0.0468 0.1311
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0001 0.0003
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0017 0.0005 0.0126
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1601 0.0661 0.0661
Toxoplasma gondii proliferation-associated protein 2G4, putative 0.0017 0.0005 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis Proliferation associated protein 2G4 0.0017 0.0005 0.0005
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.0029 0.001 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0007 0.0001 0.0003
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0046 0.0017 0.0048
Trypanosoma brucei methionine aminopeptidase, putative 0.0017 0.0005 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.0287 0.0117 0.0117
Trypanosoma brucei Xaa-Pro aminopeptidase, putative 0.0156 0.0063 0.0175
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0012 0.0033
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0002 0.0005
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0013
Plasmodium vivax proliferation-associated protein 2g4, putative 0.0017 0.0005 0.0126
Entamoeba histolytica hypothetical protein, conserved 0.0159 0.0064 0.1623
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.0174 0.0174
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0007 0.0001 0.0007
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0156 0.0063 0.0175
Echinococcus multilocularis musashi 0.0028 0.001 0.0009
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0007 0.0001 0.0007
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0002 0.0041
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0017 0.0005 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0001 0.0027
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0215 0.0087 0.0244
Echinococcus granulosus Ankyrin 0.0015 0.0004 0.0004
Echinococcus granulosus expressed protein 0.0035 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Leishmania major hypothetical protein, conserved 0.0017 0.0005 0.0014
Chlamydia trachomatis methionine aminopeptidase 0.0017 0.0005 0.0334
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0006 0.0017
Mycobacterium ulcerans aminopeptidase 0.0098 0.0039 0.0269
Brugia malayi Serine carboxypeptidase S28 family protein 0.0046 0.0017 0.0048
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.001 0.0027
Plasmodium falciparum FACT complex subunit SPT16, putative 0.0017 0.0005 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0012 0.0312
Brugia malayi Death domain containing protein 0.0015 0.0004 0.0011
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0013 0.0323
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0004
Echinococcus granulosus allatostatin A receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0006 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0015 0.0043
Leishmania major cytochrome p450-like protein 0.0007 0.0001 0.0003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0287 0.0117 0.0117
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0089 0.0035 0.0097
Onchocerca volvulus Neuropeptide F receptor homolog 0.0287 0.0117 0.0328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0006 0.0152
Echinococcus granulosus Dipeptidyl peptidase 9 0.1134 0.0468 0.0468
Echinococcus multilocularis methionine aminopeptidase, type I 0.0017 0.0005 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0014 0.0014
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0006 0.0152
Echinococcus granulosus transcription factor Dp 1 0.004 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0005 0.0014
Brugia malayi Sulfatase family protein 0.0009 0.0002 0.0004
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0002 0.0043
Loa Loa (eye worm) melatonin receptor type 1A 0.0287 0.0117 0.0328
Echinococcus granulosus 7TM GPCR rhodopsin 0.0287 0.0117 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0007 0.0001 0.0003
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0043 0.0016 0.0044
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0004 0.0012
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0007 0.0001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0003
Trypanosoma brucei oligopeptidase b 0.3459 0.1432 0.4012
Echinococcus multilocularis fmrfamide receptor 0.0287 0.0117 0.0117
Onchocerca volvulus 0.0046 0.0017 0.0048
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.1134 0.0468 0.1311
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0046 0.0017 0.0436
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0046 0.0017 0.0048
Schistosoma mansoni Xaa-Pro dipeptidase (M24 family) 0.0043 0.0016 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.8615 0.3568 1
Schistosoma mansoni cpg binding protein 0.003 0.001 0.0029
Mycobacterium ulcerans methionine aminopeptidase 0.0017 0.0005 0.0035
Onchocerca volvulus 0.003 0.001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Trypanosoma cruzi aminopeptidase P1, putative 0.0156 0.0063 0.0175
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0003
Giardia lamblia Alanyl dipeptidyl peptidase 0.0953 0.0393 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0006 0.0017
Echinococcus granulosus serotonin receptor 0.0287 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus leucyl aminopeptidase 0.0043 0.0016 0.0016
Echinococcus multilocularis neuropeptides capa receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0046 0.0017 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0007 0.0001 0.0003
Onchocerca volvulus Dipeptidase C homolog 0.0043 0.0016 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.8615 0.3568 1
Schistosoma mansoni biogenic amine receptor 0.0287 0.0117 0.0328
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.1134 0.0468 0.1312
Echinococcus multilocularis sex peptide receptor 0.0287 0.0117 0.0117
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0017 0.0005 0.0014
Schistosoma mansoni intermediate filament proteins 0.0028 0.001 0.0027
Brugia malayi Dopamine receptor protein 2 0.0287 0.0117 0.0328
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0026 0.0074
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus intermediate filament protein 0.0028 0.001 0.0009
Loa Loa (eye worm) neuropeptide F receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0.0001 0.0003
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.003 0.003
Schistosoma mansoni amine GPCR 0.0287 0.0117 0.0328
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.001 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis neuropeptide receptor 0.0287 0.0117 0.0117
Brugia malayi larval opioid receptor 0.0287 0.0117 0.0328
Trypanosoma brucei prolyl endopeptidase 0.8615 0.3568 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0001 0.0003
Schistosoma mansoni neuropeptide f receptor 76f 0.0287 0.0117 0.0328
Schistosoma mansoni rotamase 0.0035 0.0012 0.0034
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0046 0.0017 0.0048
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Onchocerca volvulus 0.0028 0.001 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis acylamino acid releasing enzyme 0.0953 0.0393 0.0393
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0287 0.0117 0.0328
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0017 0.0005 0.0014
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0004 0.0104
Schistosoma mansoni biogenic amine (5HT) receptor 0.0287 0.0117 0.0328
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0006 0.0017
Loa Loa (eye worm) DNA-binding protein 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0287 0.0117 0.0328
Brugia malayi GnHR receptor homolog 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni amine GPCR 0.0287 0.0117 0.0328
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0215 0.0087 0.0244
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0003
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0363 0.0148 0.1036
Onchocerca volvulus 0.0287 0.0117 0.0328
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.3459 0.1432 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0953 0.0393 0.1102
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0002 0.0011
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0006 0.0254
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0027
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0156 0.0063 0.0175
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Leishmania major cytochrome p450-like protein 0.0016 0.0005 0.0013
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0006 0.0152
Echinococcus multilocularis serotonin receptor 0.0287 0.0117 0.0117
Mycobacterium leprae putative cytochrome p450 0.0007 0.0001 0.0007
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0.0001 0.0003
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0007 0.0001 0.0003
Brugia malayi neuropeptide F receptor 0.0287 0.0117 0.0328
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.1134 0.0468 0.1311
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1601 0.0661 0.0661
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0016 0.0044
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0287 0.0117 0.0328
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0043 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0004 0.0004
Schistosoma mansoni DNA helicase recq5 0.0009 0.0002 0.0005
Leishmania major aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24 0.0043 0.0016 0.0044
Toxoplasma gondii methionine aminopeptidase 0.0017 0.0005 0.0014
Echinococcus multilocularis leucyl aminopeptidase 0.0043 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.0715 0.0295 0.0294
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0863 0.0356 0.0356
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Echinococcus multilocularis leucyl aminopeptidase 0.0043 0.0016 0.0016
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Brugia malayi hypothetical protein 0.0126 0.005 0.0141
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0017 0.0005 0.0126
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0287 0.0117 0.0117
Loa Loa (eye worm) prolyl oligopeptidase 0.1601 0.0661 0.1854
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0007 0.0001 0.0007
Brugia malayi CXXC zinc finger family protein 0.003 0.001 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0007 0.0001 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 2.4137 1 1
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0017 0.0005 0.0014
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0017 0.0005 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.3459 0.1432 0.4512
Giardia lamblia Xaa-Pro dipeptidase 0.0043 0.0016 0.0403
Schistosoma mansoni hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus multilocularis fmrfamide receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Trypanosoma brucei prolyl oligopeptidase, putative 0.3459 0.1432 0.4012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0006 0.0042
Brugia malayi metallopeptidase family M24 containing protein 0.0043 0.0016 0.0044
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0017 0.0005 0.0126
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0026 0.0074
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0026 0.0672
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0007 0.0001 0.0003
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0953 0.0393 1
Echinococcus granulosus methionine aminopeptidase type I 0.0017 0.0005 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0054 0.002 0.0056
Schistosoma mansoni aminopeptidase P1 (M24 family) 0.0058 0.0022 0.0062
Toxoplasma gondii leucyl aminopeptidase LAP 0.0363 0.0148 0.0416
Giardia lamblia Methionine aminopeptidase 0.0017 0.0005 0.0126
Onchocerca volvulus 0.0287 0.0117 0.0328
Echinococcus multilocularis G protein coupled receptor 139 0.0287 0.0117 0.0117
Brugia malayi prolyl oligopeptidase family protein 0.0953 0.0393 0.1102
Echinococcus granulosus death domain containing protein 0.0015 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0007 0.0001 0.0007
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Echinococcus granulosus neuropeptide receptor 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0002 0.0005
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.1134 0.0468 0.1311
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0007 0.0001 0.0007
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0017 0.0005 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0046 0.0017 0.044
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Loa Loa (eye worm) methionine aminopeptidase type I 0.0017 0.0005 0.0014
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0287 0.0117 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0007 0.0001 0.0003
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0003 0.0002
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0863 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni hypothetical protein 0.0287 0.0117 0.0328
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1601 0.0661 0.1854
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0287 0.0117 0.0328
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0017 0.0005 0.0014
Trypanosoma cruzi aminopeptidase P, putative 0.0014 0.0004 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0005 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus multilocularis g protein coupled receptor 0.0287 0.0117 0.0117
Giardia lamblia Serine peptidase, putative 0.0046 0.0017 0.0436
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0007 0.0001 0.0007
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0363 0.0148 0.3774
Chlamydia trachomatis aminopeptidase P 0.0098 0.0039 0.2596
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0001 0.0018
Onchocerca volvulus 0.0287 0.0117 0.0328
Onchocerca volvulus 0.0287 0.0117 0.0328
Brugia malayi hypothetical protein 0.0181 0.0073 0.0204
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0002 0.0011
Schistosoma mansoni microtubule-associated protein tau 0.0715 0.0295 0.0825
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus somatostatin receptor 0.0287 0.0117 0.0117
Schistosoma mansoni leucine aminopeptidase 0.0043 0.0016 0.0044
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0006 0.0006
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0002 0.0041
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0043 0.0016 0.0044
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0002 0.0006
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0046 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0017 0.0048
Brugia malayi metallopeptidase family M24 containing protein 0.0017 0.0005 0.0014
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0007 0.0001 0.0007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni lamin 0.0028 0.001 0.0027
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Brugia malayi Serine protease Z688.6 precursor 0.0046 0.0017 0.0048
Echinococcus granulosus cpg binding protein 0.0031 0.0011 0.0011
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.3459 0.1432 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0026 0.0074
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0002 0.0005
Echinococcus multilocularis expressed protein 0.0035 0.0012 0.0012
Mycobacterium ulcerans dipeptidase PepE 0.0098 0.0039 0.0269
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0841 0.0346 0.0346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Onchocerca volvulus 0.0287 0.0117 0.0328
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0046 0.0017 0.0017
Echinococcus granulosus xaa Pro dipeptidase 0.0043 0.0016 0.0016
Loa Loa (eye worm) cytochrome P450 0.0007 0.0001 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0005 0.0013
Brugia malayi Melatonin receptor type 1A 0.0287 0.0117 0.0328
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Chlamydia trachomatis cytosol aminopeptidase 0.0363 0.0148 1
Brugia malayi sulfakinin receptor protein 0.0287 0.0117 0.0328
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0005 0.0033
Giardia lamblia Alanyl dipeptidyl peptidase 0.0953 0.0393 1
Brugia malayi Serotonin receptor 0.0287 0.0117 0.0328
Brugia malayi Dopamine receptor 0.0287 0.0117 0.0328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0017 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Echinococcus multilocularis G-protein coupled receptor, putative 0.0287 0.0117 0.0117
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0003 0.0076
Echinococcus multilocularis cpg binding protein 0.0031 0.0011 0.0011
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0007 0.0001 0.0003
Schistosoma mansoni opsin-like receptor 0.0287 0.0117 0.0328
Wolbachia endosymbiont of Brugia malayi Xaa-Pro aminopeptidase 0.0156 0.0063 0.4119
Echinococcus granulosus neuropeptides capa receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0953 0.0393 0.1102
Loa Loa (eye worm) neuropeptide F receptor 0.0287 0.0117 0.0328
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0953 0.0393 0.1102
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.3459 0.1432 0.4012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0007 0.0001 0.0003
Echinococcus granulosus sex peptide receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0043 0.0016 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis dro:myosuppressin receptor 0.0287 0.0117 0.0117
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0953 0.0393 0.1102
Echinococcus granulosus alpha 1A adrenergic receptor 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Leishmania major oligopeptidase b 0.3459 0.1432 0.4012
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0007
Entamoeba histolytica peptidase, putative 0.0017 0.0005 0.013
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0046 0.0017 0.0017
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0001 0.0003
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0017 0.0005 0.0126
Trypanosoma brucei Facilitates chromatin transcription complex subunit spt16 0.0017 0.0005 0.0014
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0007 0.0001 0.0007
Giardia lamblia Hypothetical protein 0.0009 0.0002 0.0041
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0287 0.0117 0.0328
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0003 0.0007
Plasmodium vivax methionine aminopeptidase 2, putative 0.0017 0.0005 0.0126
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0006 0.0959
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.1134 0.0468 0.1311
Schistosoma mansoni neuropeptide receptor 0.0287 0.0117 0.0328
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0007 0.0001 0.0003
Brugia malayi prolyl oligopeptidase family protein 0.0953 0.0393 0.1102
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0017 0.0436
Echinococcus granulosus neuropeptide Y receptor 0.0287 0.0117 0.0117
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0007 0.0001 0.0007
Loa Loa (eye worm) intermediate filament protein 0.0028 0.001 0.0027
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0215 0.0087 0.0244
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Schistosoma mansoni cpg binding protein 0.0031 0.0011 0.0031
Echinococcus granulosus leucyl aminopeptidase 0.0043 0.0016 0.0016
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0363 0.0148 0.0468
Echinococcus granulosus biogenic amine 5HT receptor 0.0287 0.0117 0.0117
Schistosoma mansoni neuropeptide receptor 0.0287 0.0117 0.0328
Brugia malayi Aminopeptidase P, N-terminal domain containing protein 0.0026 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0026
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0287 0.0117 0.0328
Echinococcus granulosus neuropeptide Y receptor 0.0287 0.0117 0.0117
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0001 0.0003
Mycobacterium tuberculosis Dipeptidase PepE 0.0098 0.0039 0.0121
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0953 0.0393 0.1102
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus acylamino acid releasing enzyme 0.0953 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0424 0.0174 0.0487
Echinococcus multilocularis neuropeptide Y receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0005
Echinococcus granulosus dro:myosuppressin receptor 0.0287 0.0117 0.0117
Echinococcus granulosus tm gpcr rhodopsin 0.0287 0.0117 0.0117
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.3459 0.1432 0.4012
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.7661 0.3173 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0001 0.0003
Brugia malayi prolyl oligopeptidase family protein 0.1601 0.0661 0.1854
Brugia malayi Serine protease Z688.6 precursor 0.0046 0.0017 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0953 0.0393 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.003 0.003
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0017 0.0005 0.0005
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0287 0.0117 0.0328
Brugia malayi metallopeptidase family M24 containing protein 0.0156 0.0063 0.0175
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0006 0.0152
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0014 0.0039
Brugia malayi initiation factor 2-associated protein. 0.0017 0.0005 0.0014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0001 0.0018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0287 0.0117 0.0117
Entamoeba histolytica aminopeptidase, putative 0.0156 0.0063 0.1592
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0001 0.0001
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Onchocerca volvulus 0.0287 0.0117 0.0328
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Schistosoma mansoni cpg binding protein 0.0031 0.0011 0.0031
Loa Loa (eye worm) prolyl oligopeptidase 0.0953 0.0393 0.1102
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus microtubule associated protein 2 0.0715 0.0295 0.0294
Schistosoma mansoni growth hormone secretagogue receptor 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0017 0.0436
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0287 0.0117 0.0328
Plasmodium falciparum methionine aminopeptidase 2 0.0017 0.0005 0.0126
Schistosoma mansoni opsin-like receptor 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Plasmodium falciparum aminopeptidase P 0.0156 0.0063 0.1589
Mycobacterium ulcerans cytoplasmic peptidase PepQ 0.0098 0.0039 0.0269
Onchocerca volvulus 0.0287 0.0117 0.0328
Schistosoma mansoni neuropeptide F-like receptor 0.0287 0.0117 0.0328
Brugia malayi DNA-binding protein, 42 kDa containing protein 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0953 0.0393 1
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0012 0.0034
Brugia malayi Dopamine receptor protein 1 0.0287 0.0117 0.0328
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0287 0.0117 0.0117
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0287 0.0117 0.0117
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.3459 0.1432 0.4012
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0001 0.0001
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0287 0.0117 0.0328
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0004 0.0012
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Mycobacterium leprae Probable cytoplasmic peptidase PepQ 0.0098 0.0039 0.0269
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0001 0.0003
Echinococcus granulosus bloom syndrome protein 0.0022 0.0007 0.0007
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0012 0.0033
Giardia lamblia Hypothetical protein 0.0009 0.0002 0.0041
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0017 0.0005 0.0126
Echinococcus granulosus xaa Pro dipeptidase 0.0043 0.0016 0.0016
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.3459 0.1432 0.4012
Brugia malayi Tachykinin-like peptides receptor 99D 0.0287 0.0117 0.0328
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0002 0.0005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0012 0.0033
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0017 0.0005 0.0035
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Echinococcus multilocularis rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Onchocerca volvulus 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus granulosus g protein coupled receptor 0.0287 0.0117 0.0117
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0287 0.0117 0.0328
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0287 0.0117 0.0117
Brugia malayi neuropeptide F receptor 0.0287 0.0117 0.0328
Echinococcus granulosus g protein coupled receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis Xaa Pro aminopeptidase 3 0.0043 0.0016 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0007 0.0001 0.0003
Brugia malayi putative neuropeptide receptor 0.0287 0.0117 0.0328
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0953 0.0393 0.1102
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0021 0.006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0287 0.0117 0.0328
Entamoeba histolytica hypothetical protein, conserved 0.0953 0.0393 1
Mycobacterium ulcerans hydrolase 0.0009 0.0002 0.0011
Echinococcus multilocularis orexin receptor type 2 0.0287 0.0117 0.0117
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0017 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0007 0.0001 0.0003
Schistosoma mansoni netrin receptor unc5 0.0015 0.0004 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus granulosus 7tm_1 domain containing protein 0.0287 0.0117 0.0117
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0004 0.0011
Trichomonas vaginalis helicase, putative 0.0007 0.0001 0.0018
Mycobacterium tuberculosis Probable sulfatase 0.0009 0.0002 0.0005
Trichomonas vaginalis rotamase, putative 0.0035 0.0012 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis leucyl aminopeptidase 0.0043 0.0016 0.0016
Onchocerca volvulus FACT complex subunit SPT16 homolog 0.0017 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0287 0.0117 0.0328
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Toxoplasma gondii creatinase domain-containing protein 0.0156 0.0063 0.0175
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0014 0.0014
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0287 0.0117 0.0117
Plasmodium falciparum peptidase, putative 0.0953 0.0393 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Mycobacterium ulcerans sulfatase 0.0009 0.0002 0.0011
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0012 0.0033
Echinococcus granulosus tachykinin peptides receptor 99D 0.0287 0.0117 0.0117
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0026 0.0074
Onchocerca volvulus 0.0028 0.001 0.0027
Echinococcus multilocularis FACT complex subunit SPT16 0.0017 0.0005 0.0005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0026 0.0074
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0287 0.0117 0.0328
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0004 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0287 0.0117 0.0117
Plasmodium falciparum M17 leucyl aminopeptidase 0.0215 0.0087 0.2216
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0007 0.0001 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0287 0.0117 0.0328
Schistosoma mansoni ap endonuclease 0.0019 0.0006 0.0017
Toxoplasma gondii hypothetical protein 0.0953 0.0393 0.1102
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0003 0.0071
Echinococcus granulosus Proliferation associated protein 2G4 0.0017 0.0005 0.0005
Echinococcus granulosus hypothetical protein 0.0287 0.0117 0.0117
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0026 0.0026
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.0001 0.0001
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Brugia malayi intermediate filament protein 0.0028 0.001 0.0027
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0017 0.0005 0.0035
Leishmania major transcription factor-like protein 0.0017 0.0005 0.0014
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0004 0.0004
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0043 0.0016 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0001 0.0018
Loa Loa (eye worm) metallopeptidase family M24 containing protein 0.0017 0.0005 0.0014
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0004 0.0011
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0013
Echinococcus granulosus g-protein coupled receptor 0.0287 0.0117 0.0117
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0043 0.0016 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0006 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0287 0.0117 0.0117
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0287 0.0117 0.0117
Echinococcus multilocularis lamin dm0 0.0028 0.001 0.0009
Entamoeba histolytica prolyl oligopeptidase family protein 0.0953 0.0393 1
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0017 0.0005 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis prolyl endopeptidase 0.8615 0.3568 0.3568
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1601 0.0661 0.1854
Brugia malayi Serotonin receptor 0.0287 0.0117 0.0328
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0002 0.0007
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0007 0.0001 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0287 0.0117 0.0117
Echinococcus multilocularis serotonin receptor 0.0287 0.0117 0.0117
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0007 0.0001 0.0007
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0004 0.0003
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0003 0.0007
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0043 0.0016 0.0044
Mycobacterium ulcerans leucyl aminopeptidase 0.0363 0.0148 0.1036
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0046 0.0017 0.044
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0017 0.0005 0.0014
Schistosoma mansoni histamine h1 receptor 0.0287 0.0117 0.0328
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0043 0.0016 0.0044
Brugia malayi prolyl oligopeptidase family protein 0.1134 0.0468 0.1311
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0287 0.0117 0.0117
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403
Treponema pallidum methionine aminopeptidase (map) 0.0017 0.0005 0.0794
Schistosoma mansoni amine GPCR 0.0287 0.0117 0.0328
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0005 0.0013
Echinococcus granulosus Xaa Pro aminopeptidase 3 0.0043 0.0016 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0005 0.0013
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0013 0.0323
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0004 0.0011
Onchocerca volvulus 0.0287 0.0117 0.0328
Entamoeba histolytica methionine aminopeptidase, putative 0.0017 0.0005 0.013
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0017 0.0005 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Brugia malayi cytochrome P450 0.0007 0.0001 0.0003
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0046 0.0017 0.0048
Brugia malayi G protein-coupled receptor F59B2.13 0.0287 0.0117 0.0328
Echinococcus granulosus lamin 0.0028 0.001 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Brugia malayi Cytochrome P450 family protein 0.0007 0.0001 0.0003
Plasmodium falciparum proliferation-associated protein 2g4, putative 0.0017 0.0005 0.0126
Toxoplasma gondii transcriptional elongation factor FACT140 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni neuropeptide receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis neuropeptide receptor 0.0287 0.0117 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0287 0.0117 0.0117
Echinococcus granulosus prolyl endopeptidase 0.8615 0.3568 0.3568
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0001 0.0001
Onchocerca volvulus 0.0287 0.0117 0.0328
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0287 0.0117 0.0328
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0007 0.0001 0.0007
Echinococcus granulosus leucine aminopeptidase protein 0.0363 0.0148 0.0148
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0953 0.0393 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0007 0.0001 0.0007
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0007 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0017 0.0005 0.0184
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0012 0.0307
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0287 0.0117 0.0117
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0026 0.0074
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0008
Leishmania major methionine aminopeptidase 2, putative 0.0017 0.0005 0.0014
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0002 0.0006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0014 0.0039
Schistosoma mansoni neuropeptide receptor 0.0287 0.0117 0.0328
Brugia malayi ORL1-like opioid receptor 0.0287 0.0117 0.0328
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0007 0.0001 0.0003
Leishmania major cytochrome p450-like protein 0.0007 0.0001 0.0003
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis neuropeptide receptor A26 0.0287 0.0117 0.0117
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0287 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0043 0.0016 0.0044
Giardia lamblia Thymus-specific serine protease precursor 0.0046 0.0017 0.0436
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0001 0.0003
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0012 0.0034
Brugia malayi RE15519p 0.0287 0.0117 0.0328
Entamoeba histolytica prolyl oligopeptidase family protein 0.0953 0.0393 1
Mycobacterium tuberculosis Possible hydrolase 0.0009 0.0002 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0287 0.0117 0.0117
Loa Loa (eye worm) initiation factor 2-associated protein 0.0017 0.0005 0.0014
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni peptidase 0.0017 0.0005 0.0014
Echinococcus multilocularis xaa Pro dipeptidase 0.0043 0.0016 0.0016
Schistosoma mansoni amine GPCR 0.0287 0.0117 0.0328
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0287 0.0117 0.0328
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0005 0.0013
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0.0001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0287 0.0117 0.0328
Loa Loa (eye worm) RecQ helicase 0.0022 0.0007 0.002
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0006 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.001 0.0027
Schistosoma mansoni cytochrome P450 0.0007 0.0001 0.0003
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0953 0.0393 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0001 0.0001
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0089 0.0035 0.0097
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0006 0.0156
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0001 0.0001
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0002 0.0043
Onchocerca volvulus 0.0287 0.0117 0.0328
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0003 0.0007
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0012 0.0034
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0002 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0953 0.0393 0.1102
Schistosoma mansoni 60S ribosomal protein L21 0.0006 0.0001 0.0001
Echinococcus multilocularis Ankyrin 0.0015 0.0004 0.0004
Brugia malayi G-protein coupled receptor 0.0287 0.0117 0.0328
Onchocerca volvulus 0.0287 0.0117 0.0328
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.1134 0.0468 0.1311
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0287 0.0117 0.0328
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0215 0.0087 0.0244
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0017 0.0005 0.0016
Brugia malayi putative neuropeptide receptor NPR1 0.0287 0.0117 0.0328
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0017 0.0005 0.0126
Onchocerca volvulus 0.0095 0.0037 0.0105
Echinococcus multilocularis neuropeptide s receptor 0.0287 0.0117 0.0117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0004 0.0011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0287 0.0117 0.0328
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0007 0.018
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0007 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0007 0.0001 0.0007
Schistosoma mansoni biogenic amine receptor 0.0287 0.0117 0.0328
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0007 0.0001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Schistosoma mansoni lamin 0.0028 0.001 0.0027
Echinococcus granulosus lamin dm0 0.0028 0.001 0.0009
Echinococcus granulosus fmrfamide receptor 0.0287 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0003
Trypanosoma cruzi oligopeptidase b 0.3459 0.1432 0.4012
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Giardia lamblia Xaa-Pro dipeptidase 0.0017 0.0005 0.0126
Schistosoma mansoni chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) 0.0017 0.0005 0.0014
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0007 0.002
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0017 0.0005 0.0014
Trypanosoma brucei aminopeptidase, putative 0.0043 0.0016 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis neuropeptides capa receptor 0.0287 0.0117 0.0117
Echinococcus multilocularis 0.0007 0.0001 0.0001
Onchocerca volvulus Prolyl endopeptidase homolog 0.8615 0.3568 1
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0041
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0002 0.0011
Plasmodium vivax peptidase, putative 0.0156 0.0063 0.1589
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0287 0.0117 0.0117
Treponema pallidum aminopeptidase P 0.0156 0.0063 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0007 0.0001 0.0003
Schistosoma mansoni alpha-1 adrenergic receptor 0.0287 0.0117 0.0328
Brugia malayi Uncoordinated protein 44 0.0015 0.0004 0.0011
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0017 0.0005 0.0126
Entamoeba histolytica prolyl oligopeptidase family protein 0.0953 0.0393 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0287 0.0117 0.0117
Echinococcus granulosus dnaJ subfamily B 0.0424 0.0174 0.0174
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0046 0.0017 0.0436
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis xaa pro aminopeptidase 0.0156 0.0063 0.0062
Brugia malayi G-protein coupled receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0026 0.0026
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0017 0.0005 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0003 0.0002
Echinococcus granulosus neuropeptide receptor 0.0287 0.0117 0.0117
Trypanosoma cruzi aminopeptidase P, putative 0.0043 0.0016 0.0044
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0026 0.0074
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0008
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0863 0.0356 0.0997
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0046 0.0017 0.0436
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0007 0.0001 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0287 0.0117 0.0117
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0363 0.0148 1
Plasmodium vivax methionine aminopeptidase 1c, putative 0.0017 0.0005 0.0126
Loa Loa (eye worm) hypothetical protein 0.0046 0.0017 0.0048
Brugia malayi G protein-coupled receptor 0.0287 0.0117 0.0328
Echinococcus multilocularis allatostatin A receptor 0.0287 0.0117 0.0117
Echinococcus granulosus g protein coupled receptor 0.0287 0.0117 0.0117
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0287 0.0117 0.0117
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0287 0.0117 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0953 0.0393 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0006 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0015 0.0043
Trypanosoma cruzi prolyl endopeptidase 0.8615 0.3568 1
Onchocerca volvulus 0.0287 0.0117 0.0328
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.8615 0.3568 1
Mycobacterium ulcerans dipeptidase 0.0098 0.0039 0.0269
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0017 0.0005 0.0126
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0046 0.0017 0.044
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0007 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Toxoplasma gondii prolyl endopeptidase 0.8615 0.3568 1
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0003 0.0002
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0005
Brugia malayi hypothetical protein 0.0287 0.0117 0.0328
Echinococcus granulosus peptide allatostatin:somatostatin 0.0287 0.0117 0.0117
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0029 0.001 0.0028
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0287 0.0117 0.0328
Schistosoma mansoni adenoreceptor 0.0287 0.0117 0.0328
Echinococcus multilocularis neuropeptide Y receptor 0.0287 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0018
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0016 0.0403

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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