Detailed information for compound 1554785

Basic information

Technical information
  • TDR Targets ID: 1554785
  • Name: 1-(2-chloro-4-fluorophenoxy)-3-(2-methoxyphen yl)sulfonylpropan-2-ol
  • MW: 374.812 | Formula: C16H16ClFO5S
  • H donors: 1 H acceptors: 3 LogP: 2.91 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1S(=O)(=O)CC(COc1ccc(cc1Cl)F)O
  • InChi: 1S/C16H16ClFO5S/c1-22-15-4-2-3-5-16(15)24(20,21)10-12(19)9-23-14-7-6-11(18)8-13(14)17/h2-8,12,19H,9-10H2,1H3
  • InChiKey: NJAJQTWTPCRFAA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-chloro-4-fluoro-phenoxy)-3-(2-methoxyphenyl)sulfonyl-propan-2-ol
  • Bionet1_004655
  • 1-(2-chloro-4-fluorophenoxy)-3-[(2-methoxyphenyl)sulfonyl]-2-propanol
  • MLS000721585
  • SMR000335896
  • 7R-1270
  • Oprea1_639703

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0042 0.0045
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0027 0.0004
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.025 0.0957 0.3193
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0155 0.0518
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0155 0.0518
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0027 0.0146
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0689 0.2738 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0056 0.0378
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0034 0.1179
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0147 0.0195
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0155 0.0208
Plasmodium falciparum glutathione reductase 0.0021 0.0026 0.0757
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0234 0.1135
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0155 0.0518
Entamoeba histolytica deoxycytidyl transferase, putative 0.0029 0.0059 0.0436
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0076 0.0253
Trypanosoma cruzi ISWI complex protein 0.0031 0.0065 0.0446
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0053 0.0178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Entamoeba histolytica hypothetical protein 0.0023 0.0034 0.0214
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0021 0.0026 0.0015
Brugia malayi serine/threonine-protein kinase plk-2 0.0293 0.113 0.3771
Schistosoma mansoni ran 0.0021 0.0025 0.0022
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0054 0.0158 0.0487
Loa Loa (eye worm) hypothetical protein 0.0056 0.0166 0.0553
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0085 0.0282
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0034 0.0303
Brugia malayi Importin beta-1 subunit 0.0028 0.0056 0.0186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0205 0.0279
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0066 0.0081
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0042 0.0032
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0061 0.0186 0.0888
Onchocerca volvulus Huntingtin homolog 0.025 0.0957 0.3163
Brugia malayi ecdysteroid receptor 0.0053 0.0155 0.0518
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Schistosoma mansoni terminal deoxycytidyl transferase 0.0029 0.0059 0.007
Brugia malayi PHD-finger family protein 0.0032 0.0069 0.023
Brugia malayi conserved hypotetical protein 0.0025 0.0042 0.0139
Toxoplasma gondii heat shock protein HSP90 0.0067 0.0213 0.1891
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0234 0.165
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.018
Onchocerca volvulus 0.0032 0.0069 0.0187
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0054 0.018
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0466 0.0651
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Trypanosoma cruzi ISWI complex protein 0.0031 0.0065 0.0446
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0018 0.0014 0.0069
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.0362 0.0503
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0345 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0073 0.0375
Echinococcus granulosus dnaJ subfamily C 6 0.0019 0.0018 0.0012
Echinococcus granulosus endoplasmin 0.0054 0.0158 0.0211
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Echinococcus granulosus transcription factor btf3 0.0035 0.0081 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0155 0.0518
Onchocerca volvulus Peroxidasin homolog 0.0033 0.0076 0.021
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0155 0.0145
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0066 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0274 0.0377
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.0466 0.1555
Loa Loa (eye worm) hypothetical protein 0.0082 0.0274 0.0914
Loa Loa (eye worm) hypothetical protein 0.0072 0.0234 0.0781
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0049 0.0055
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0034 0.0032
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.0415
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0352 0.1368 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0021 0.0026 0.0757
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0139 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0014 0.0071
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0166 0.0223
Toxoplasma gondii NADPH-glutathione reductase 0.0021 0.0026 0.0227
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0101 0.013
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0155 0.0518
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0042 0.0139
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0138 0.0501 0.2517
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0293 0.113 0.16
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0194 0.0729 0.3653
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0054 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Plasmodium vivax SET domain protein, putative 0.0065 0.0205 0.9615
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0028 0.0052 0.013
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0234 0.2
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0042 0.0045
Schistosoma mansoni hypothetical protein 0.0065 0.0204 0.0278
Brugia malayi CXXC zinc finger family protein 0.0151 0.0552 0.1841
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0194 0.0727 0.1024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Echinococcus multilocularis protein dispatched 1 0.0102 0.0354 0.0344
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.012 0.0109
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0027 0.0136
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0139 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0155 0.0518
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0021 0.0026 0.0022
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0062
Schistosoma mansoni endoplasmin 0.0067 0.0213 0.029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0155 0.0518
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0021 0.0026 0.0757
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0166 0.0553
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0026 0.0154
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0042 0.0045
Toxoplasma gondii heat shock protein 75, putative 0.0028 0.0052 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0018 0.0014 0.0027
Schistosoma mansoni alpha-glucosidase 0.0047 0.0132 0.0174
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0234 0.0224
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0689 0.2738 1
Onchocerca volvulus Peroxidase homolog 0.0033 0.0076 0.021
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.008 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0345 0.0478
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0059 0.04
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Echinococcus multilocularis dnaJ subfamily C 6 0.0019 0.0018 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0081 0.0413
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0034 0.0032
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.0163 0.0153
Schistosoma mansoni hypothetical protein 0.0025 0.0042 0.0045
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Trypanosoma brucei heat shock protein 90, putative 0.0067 0.0213 0.153
Giardia lamblia Heat shock protein HSP 90-alpha 0.0054 0.0158 0.1395
Echinococcus multilocularis lamin dm0 0.0028 0.0053 0.0043
Schistosoma mansoni hypothetical protein 0.0304 0.1175 0.1665
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Brugia malayi MAP kinase sur-1 0.0018 0.0014 0.0046
Schistosoma mansoni hypothetical protein 0.0042 0.0109 0.0141
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0056 0.0378
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0124 0.0162
Brugia malayi hypothetical protein 0.0056 0.0166 0.0554
Trypanosoma brucei Heat shock protein 83, putative 0.0067 0.0213 0.153
Trypanosoma cruzi lanosterol synthase, putative 0.0019 0.0017 0.0092
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0014 0.0071
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0069 0.0059
Echinococcus granulosus lamin 0.0028 0.0053 0.0062
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0073 0.0243
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Onchocerca volvulus 0.0021 0.0027 0.0044
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0018 0.0014 0.0069
Onchocerca volvulus 0.0053 0.0155 0.0476
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0029 0.0059 0.036
Leishmania major DNA polymerase eta, putative 0.0057 0.017 0.1175
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0155 0.0476
Trypanosoma cruzi heat shock protein 85, putative 0.0067 0.0213 0.153
Trichomonas vaginalis rotamase, putative 0.0032 0.007 0.0359
Brugia malayi Glycosyl hydrolases family 31 protein 0.0055 0.0163 0.0544
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0147 0.0489
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0166 0.769
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0109
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0076 0.0253
Brugia malayi hypothetical protein 0.0092 0.0315 0.1052
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Schistosoma mansoni importin beta-1 0.0028 0.0056 0.0066
Schistosoma mansoni cpg binding protein 0.0163 0.0602 0.0846
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.113 0.16
Echinococcus multilocularis thyroid hormone receptor alpha 0.0053 0.0155 0.0145
Plasmodium vivax importin-beta 2, putative 0.0028 0.0056 0.2257
Echinococcus multilocularis GPCR, family 2 0.0065 0.0204 0.0194
Giardia lamblia Kinase, PLK 0.0293 0.113 1
Leishmania major DNA polymerase kappa, putative 0.0029 0.0059 0.036
Echinococcus granulosus mitogen activated protein kinase 3 0.0018 0.0014 0.0005
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.007 0.044
Brugia malayi CHE-14 protein 0.0089 0.0303 0.1009
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0027 0.0162
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0027 0.0236
Schistosoma mansoni hypothetical protein 0.0086 0.0289 0.0399
Plasmodium vivax heat shock protein 90, putative 0.0028 0.0052 0.2065
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0054 0.018
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0018 0.0014 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0155 0.0518
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0138 0.0501 0.2517
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.016 0.7376
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0034 0.1179
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0139 0.042
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0081 0.0558
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0124 0.0114
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0027 0.0062
Echinococcus multilocularis zinc finger protein 0.0048 0.0135 0.0125
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0027 0.0162
Trypanosoma cruzi heat shock protein, putative 0.0028 0.0052 0.0349
Schistosoma mansoni heat shock protein 0.0028 0.0052 0.006
Trypanosoma brucei heat shock protein 84, putative 0.0028 0.0052 0.0349
Leishmania major importin beta-1 subunit, putative 0.0023 0.0034 0.0176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.018
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0069 0.0084
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0029 0.0059 0.007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0124 0.0413
Schistosoma mansoni hypothetical protein 0.0086 0.0289 0.0399
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0066 0.2775
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0124 0.0162
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0166 0.0223
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0155 0.0518
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Leishmania major mitochondrial DNA polymerase beta 0.0352 0.1368 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0065 0.0204 0.0682
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0042 0.0032
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0166 0.769
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0042 0.0032
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0028 0.0052 0.006
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0162
Onchocerca volvulus 0.0752 0.2996 1
Echinococcus granulosus snurportin 1 0.0304 0.1175 0.1665
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0028 0.0052 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0155 0.0518
Brugia malayi MH2 domain containing protein 0.0391 0.1529 0.5104
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0303 0.0418
Brugia malayi Hsp90 protein 0.0028 0.0052 0.0173
Loa Loa (eye worm) hypothetical protein 0.0094 0.0323 0.1079
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0025 0.0154
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0689 0.2738 1
Schistosoma mansoni peroxidasin 0.0033 0.0076 0.0094
Echinococcus multilocularis dnaJ subfamily B 0.174 0.7007 0.7004
Giardia lamblia NADH oxidase lateral transfer candidate 0.0021 0.0026 0.0226
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0027 0.0236
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Mycobacterium tuberculosis Probable dehydrogenase 0.0138 0.0501 0.2517
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0183 0.0247
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0069 0.0613
Echinococcus granulosus thioredoxin glutathione reductase 0.0061 0.0187 0.0253
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0155 0.0208
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0059 0.04
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Echinococcus granulosus cpg binding protein 0.0163 0.0602 0.0846
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0017 0.001 0.0052
Schistosoma mansoni mixed-lineage leukemia protein mll 0.005 0.0144 0.0191
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0166 0.0223
Loa Loa (eye worm) TAR-binding protein 0.0129 0.0466 0.1555
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.0466 0.1555
Brugia malayi Pax transcription factor protein 2 0.017 0.0629 0.2099
Echinococcus granulosus zinc finger protein 0.0048 0.0135 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0155 0.0145
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0025 0.0225
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0092 0.0315 0.0436
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Loa Loa (eye worm) hypothetical protein 0.01 0.0345 0.115
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0129 0.0463 0.0647
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0204 0.0682
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0026 0.0154
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0303 0.1009
Echinococcus multilocularis peroxidasin 0.0033 0.0076 0.0066
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0155 0.0208
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0124 0.0163
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0018 0.0014 0.0069
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0042 0.0139
Brugia malayi nuclear receptor NHR-88 0.0025 0.0042 0.0139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.0775 0.2586
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0303 0.0418
Schistosoma mansoni microtubule-associated protein tau 0.0745 0.2964 0.4222
Mycobacterium tuberculosis Conserved hypothetical protein 0.0185 0.0692 0.3503
Brugia malayi nuclear hormone receptor 0.0053 0.0155 0.0518
Giardia lamblia DINP protein human, muc B family 0.0029 0.0059 0.0523
Leishmania major DNA polymerase eta, putative 0.0036 0.0088 0.0572
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.0775 0.2586
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0025 0.0226
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0204 0.0194
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0027 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0023
Onchocerca volvulus 0.0072 0.0234 0.074
Echinococcus multilocularis musashi 0.0028 0.0053 0.0043
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.069 0.227
Brugia malayi DnaJ domain containing protein 0.0019 0.0018 0.0061
Schistosoma mansoni hypothetical protein 0.0032 0.0069 0.0084
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0066 0.0056
Trypanosoma cruzi heat shock protein 85, putative 0.0067 0.0213 0.153
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0069 0.0084
Brugia malayi PHD-finger family protein 0.0023 0.0033 0.0109
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0042 0.0045
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0034 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0145 0.0529 0.2714
Trichomonas vaginalis ran, putative 0.0021 0.0025 0.013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0138 0.0501 0.247
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0138 0.0501 0.2517
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Echinococcus multilocularis smad 0.0027 0.0049 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0466 0.0651
Trichomonas vaginalis protein kinase inhibitor, putative 0.0019 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0142 0.0518 0.1728
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0511 0.1704
Onchocerca volvulus Chorion peroxidase homolog 0.0033 0.0076 0.021
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0034 0.0175
Plasmodium vivax thioredoxin reductase, putative 0.0061 0.0186 0.8677
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0155 0.0208
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0027 0.0062
Brugia malayi TAR-binding protein 0.0129 0.0466 0.1555
Echinococcus granulosus smad 0.0027 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Toxoplasma gondii Hsp90 domain-containing protein 0.0028 0.0052 0.0462
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0032 0.0022
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0081 0.0715
Mycobacterium ulcerans hypothetical protein 0.0072 0.0234 0.0769
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Echinococcus granulosus muscleblind protein 0.0623 0.247 0.3516
Trypanosoma cruzi protein farnesyltransferase, putative 0.0017 0.001 0.0042
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0054 0.018
Echinococcus multilocularis transcription factor btf3 0.0035 0.0081 0.007
Echinococcus multilocularis Niemann Pick C1 protein 0.0297 0.1147 0.1138
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0139 0.0183
Brugia malayi PHD-finger family protein 0.0059 0.0179 0.0596
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0076 0.0253
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0049 0.0055
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0158 0.0808
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0027 0.0016
Entamoeba histolytica Ran family GTPase 0.0021 0.0025 0.0136
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0042 0.0045
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0148 0.0689
Loa Loa (eye worm) RNA binding protein 0.0129 0.0466 0.1555
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0027 0.0088
Echinococcus granulosus heat shock protein 0.0067 0.0213 0.029
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0293 0.113 0.3771
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0155 0.0518
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0166 0.0156
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0059 0.0124
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0158 0.0808
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.007 0.0534
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0155 0.0145
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0034 0.0032
Entamoeba histolytica hypothetical protein 0.0022 0.0028 0.0159
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0147 0.0195
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.0141 0.1001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.016 0.0495
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0012
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0166 0.0156
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0345 0.0478
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0154 0.0564 0.284
Trichomonas vaginalis set domain proteins, putative 0.0495 0.195 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.007 0.048
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0155 0.0145
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0208 0.0784 0.6915
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.018
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0021 0.0026 0.0113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Onchocerca volvulus 0.0033 0.0076 0.021
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0066 0.2775
Brugia malayi hypothetical protein 0.0025 0.0042 0.0139
Echinococcus granulosus heat shock protein 90 0.0054 0.0158 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.013
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.0026 0.0154
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0025 0.0154
Loa Loa (eye worm) hypothetical protein 0.0623 0.247 0.8246
Brugia malayi Niemann-Pick C1 protein precursor 0.0208 0.0784 0.2618
Schistosoma mansoni cpg binding protein 0.0151 0.0552 0.0774
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0062
Loa Loa (eye worm) thioredoxin reductase 0.0061 0.0186 0.0621
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0066 0.0455
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Trypanosoma cruzi heat shock protein 90, putative 0.0054 0.0158 0.1123
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0141 0.1001
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0025 0.0154
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0018 0.0014 0.0069
Echinococcus multilocularis heat shock protein 0.0067 0.0213 0.0203
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0246 0.0941 0.1331
Trypanosoma brucei lanosterol synthase 0.0019 0.0017 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0155 0.0518
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0155 0.0518
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0234 0.0769
Brugia malayi Blistered cuticle protein 3 0.0033 0.0076 0.0253
Echinococcus multilocularis muscleblind protein 0.0623 0.247 0.2463
Schistosoma mansoni smad1 5 8 and 0.0027 0.0049 0.0055
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.016 0.0495
Echinococcus granulosus peregrin 0.0036 0.0088 0.0112
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0032 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0234 0.0781
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0155 0.0518
Brugia malayi glutathione reductase 0.0061 0.0186 0.0621
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0056
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0042 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0466 0.0651
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0148 0.0689
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0059 0.0124
Giardia lamblia Grp94/Hsp90 0.0054 0.0158 0.1395
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0466 0.0651
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0155 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0014 0.0071
Brugia malayi Muscleblind-like protein 0.0623 0.247 0.8246
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0017 0.001 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.007 0.048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0088
Toxoplasma gondii thioredoxin reductase 0.0061 0.0186 0.1652
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0066 0.059
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.008 0.0069
Trichomonas vaginalis DNA polymerase eta, putative 0.0029 0.0059 0.0303
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0139 0.0462
Echinococcus granulosus heat shock protein 90 0.0067 0.0213 0.029
Giardia lamblia Heat shock protein HSP 90-alpha 0.0067 0.0213 0.1886
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0042 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0081 0.0413
Mycobacterium ulcerans hypothetical protein 0.0185 0.0692 0.2458
Echinococcus multilocularis heat shock protein 90 0.0054 0.0158 0.0148
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0029 0.0059 0.0049
Plasmodium vivax heat shock protein, putative 0.0028 0.0052 0.2065
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0076 0.0253
Brugia malayi Peroxidasin 0.0033 0.0076 0.0253
Brugia malayi F/Y-rich N-terminus family protein 0.0062 0.0194 0.0647
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0155 0.0208
Echinococcus multilocularis expressed conserved protein 0.0195 0.0733 0.0724
Trichomonas vaginalis glutathione reductase, putative 0.0021 0.0026 0.0131
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0274 0.0264
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Echinococcus multilocularis heat shock protein 90 0.0067 0.0213 0.0203
Brugia malayi Pre-SET motif family protein 0.0435 0.1708 0.5701
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0076 0.0253
Loa Loa (eye worm) MBCTL1 0.0056 0.0166 0.0553
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0003 0.0009
Treponema pallidum heat shock protein 90 0.0054 0.0158 0.0487
Trypanosoma cruzi protein farnesyltransferase, putative 0.0017 0.001 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0155 0.0208
Schistosoma mansoni peroxidasin 0.0033 0.0076 0.0094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0616 0.4485
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0001 0.0003
Loa Loa (eye worm) Smad1 0.0027 0.0049 0.0162
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0017 0.001 0.0052
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0037 0.0039
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0021 0.0026 0.0113
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0052 0.2065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0062
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0027 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0171
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0052 0.0267
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0057 0.017 0.1212
Brugia malayi isocitrate dehydrogenase 0.0031 0.0066 0.0221
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0081 0.0558
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0138 0.0501 0.2517
Echinococcus multilocularis mitogen activated protein kinase 3 0.0018 0.0014 0.0004
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0162
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0391 0.1529 0.5104
Brugia malayi hypothetical protein 0.0028 0.0054 0.018
Brugia malayi jmjC domain containing protein 0.0104 0.0362 0.1208
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0021 0.0026 0.0227
Trypanosoma brucei trypanothione reductase 0.0061 0.0186 0.1333
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0155 0.0208
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0021 0.0026 0.0757
Schistosoma mansoni zinc finger protein 0.0031 0.0065 0.0079
Schistosoma mansoni endoplasmin 0.0067 0.0213 0.029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0054 0.0063
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0027 0.0004
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0155 0.0518
Leishmania major GTP-binding protein, putative 0.0021 0.0025 0.0112
Echinococcus granulosus GPCR family 2 0.0065 0.0204 0.0278
Loa Loa (eye worm) hypothetical protein 0.0056 0.0166 0.0554
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0293 0.113 0.1121
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0034 0.0303
Brugia malayi hypothetical protein 0.0752 0.2996 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0042 0.0031
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0018 0.0014 0.0027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0113
Trypanosoma brucei polo-like protein kinase 0.0293 0.113 0.8253
Brugia malayi N-terminal motif family protein 0.0185 0.069 0.2304
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0001 0.0003
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0155 0.0208
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0028 0.0052 0.0042
Echinococcus multilocularis expressed protein 0.0033 0.0073 0.0063
Loa Loa (eye worm) hypothetical protein 0.0109 0.0384 0.1281
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0062
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0211 0.0797 0.1125
Schistosoma mansoni hypothetical protein 0.0086 0.0289 0.0399
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0034 0.0175
Echinococcus granulosus fetal alzheimer antigen falz 0.0054 0.0159 0.0213
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0096 0.0086
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0034 0.0032
Onchocerca volvulus Huntingtin homolog 0.025 0.0957 0.3163
Trypanosoma brucei protein kinase, putative 0.0018 0.0014 0.0069
Leishmania major trypanothione reductase 0.0061 0.0186 0.1297
Brugia malayi hypothetical protein 0.025 0.0957 0.3193
Trypanosoma brucei DNA polymerase eta, putative 0.0057 0.017 0.1212
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0139 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0081 0.0268
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0148 0.0689
Echinococcus granulosus jumonji domain containing protein 0.0044 0.012 0.0156
Brugia malayi Smad1 0.0027 0.0049 0.0162
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0079 0.0404
Brugia malayi beta-NAC-like protein 0.0035 0.0081 0.0268
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0186
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0027 0.0004
Echinococcus granulosus Smad4 0.0027 0.0049 0.0055
Leishmania major basic transcription factor 3a, putative 0.0035 0.0081 0.0518
Brugia malayi Endoplasmin precursor 0.0067 0.0213 0.0711
Trypanosoma cruzi Heat shock protein 83, putative 0.0067 0.0213 0.153
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0042 0.0139
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0054 0.0158 0.0681
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0017 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0053 0.0178
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0194 0.0729 0.6466
Entamoeba histolytica hypothetical protein 0.0092 0.0315 0.2726
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.008 0.0099
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0042 0.0032
Echinococcus multilocularis tar DNA binding protein 0.0129 0.0466 0.0456
Echinococcus granulosus importin subunit beta 1 0.0028 0.0056 0.0065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0204 0.0682
Trypanosoma cruzi heat shock protein 85, putative 0.0067 0.0213 0.153
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0466 0.0651
Echinococcus multilocularis geminin 0.076 0.3024 0.3017
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0081 0.0629
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0054 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0155 0.0518
Trichomonas vaginalis helicase, putative 0.0034 0.0079 0.0404
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0025 0.0084
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0042 0.0095
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0054 0.0158 0.0739
Brugia malayi nuclear hormone receptor 0.0025 0.0042 0.0139
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Entamoeba histolytica heat shock protein 90, putative 0.0067 0.0213 0.1813
Schistosoma mansoni transcription factor btf3 0.0035 0.0081 0.0101
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0155 0.0476
Mycobacterium tuberculosis Probable oxidoreductase 0.0154 0.0564 0.284
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0076 0.0253
Loa Loa (eye worm) endoplasmin 0.0067 0.0213 0.0711
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0322 0.1246 0.1767
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0154 0.0564 0.284
Brugia malayi RNA binding protein 0.0129 0.0466 0.1555
Entamoeba histolytica hypothetical protein 0.0035 0.0081 0.0629
Loa Loa (eye worm) MH2 domain-containing protein 0.0391 0.1529 0.5104
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.017 0.0566
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.0775 0.2586
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0121
Onchocerca volvulus Serine\/threonine kinase homolog 0.0293 0.113 0.3743
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0042 0.0032
Schistosoma mansoni smad 0.0027 0.0049 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0155 0.0518
Trypanosoma brucei unspecified product 0.0029 0.0059 0.04
Trypanosoma brucei unspecified product 0.002 0.0022 0.013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0124 0.0413
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0124 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0054 0.0158 0.0211
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0158 0.0808
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0027 0.0004
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0021 0.0026 0.0154
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0027 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0166 0.1186
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0155 0.0518
Onchocerca volvulus 0.0049 0.0139 0.042
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Giardia lamblia PHD finger protein 15 0.0032 0.0069 0.0612
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0042 0.0045
Toxoplasma gondii histone lysine methyltransferase SET1 0.0292 0.1127 1
Echinococcus granulosus tumor protein p63 0.0238 0.0907 0.1282
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Echinococcus multilocularis mitogen activated protein kinase 0.0018 0.0014 0.0004
Brugia malayi MH2 domain containing protein 0.0027 0.0049 0.0162
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0059 0.04
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0141 0.1001
Plasmodium falciparum importin beta, putative 0.0028 0.0056 0.2257
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0027 0.0121
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0056 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0141 0.1001
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Entamoeba histolytica hypothetical protein 0.0023 0.0034 0.0214
Onchocerca volvulus Dual oxidase homolog 0.0033 0.0076 0.021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Trypanosoma brucei ISWI complex protein 0.0031 0.0065 0.0446
Brugia malayi Bromodomain containing protein 0.0036 0.0088 0.0295
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0042 0.0045
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.113 0.8253
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0234 0.0769
Schistosoma mansoni alpha-glucosidase 0.0047 0.0132 0.0174
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0129 0.0463 0.0453
Echinococcus multilocularis dna polymerase kappa 0.0029 0.0059 0.0049
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0081 0.0558
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Schistosoma mansoni nuclear receptor 0.0025 0.0042 0.0045
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0108 0.0552
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Mycobacterium ulcerans heat shock protein 90 0.0054 0.0158 0.0487
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0018 0.0014 0.0046
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.007 0.048
Brugia malayi nuclear receptor NHR-67 0.0025 0.0042 0.0139
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0155 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0155 0.0518
Loa Loa (eye worm) hypothetical protein 0.0072 0.0234 0.0781
Toxoplasma gondii hypothetical protein 0.0057 0.0171 0.1513
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0049 0.0038
Brugia malayi hypothetical protein 0.0025 0.0042 0.0139
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0234 0.2
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.013
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0027 0.0004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0061 0.0187 0.0177
Schistosoma mansoni smad1 5 8 and 0.0027 0.0049 0.0055
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0017 0.001 0.0042
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0034 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.013
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Trypanosoma cruzi heat shock protein 90, putative 0.0067 0.0213 0.153
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0352 0.1368 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0139 0.0184
Echinococcus multilocularis Niemann Pick C1 protein 0.0208 0.0784 0.0775
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0155 0.0208
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0352 0.1368 1
Brugia malayi steroid hormone receptor 0.0053 0.0155 0.0518
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0139 0.0184
Loa Loa (eye worm) hypothetical protein 0.0089 0.0303 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Brugia malayi ImpB/MucB/SamB family protein 0.0029 0.0059 0.0197
Brugia malayi RNA, U transporter 1 0.0081 0.0269 0.0898
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0015 0.0075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0026 0.0154
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0246 0.0941 0.0932
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0234 0.0781
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0275 0.0379
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0303 0.1551
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0049 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0042 0.0045
Schistosoma mansoni SET domain protein 0.0018 0.0013 0.0005
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0109 0.0363
Plasmodium vivax endoplasmin, putative 0.0067 0.0213 1
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0017 0.001 0.0052
Loa Loa (eye worm) oxidoreductase 0.0021 0.0027 0.0088
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0017 0.001 0.0033
Brugia malayi Pre-SET motif family protein 0.0065 0.0205 0.0685
Echinococcus granulosus tar DNA binding protein 0.0129 0.0466 0.0651
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0027 0.0004
Onchocerca volvulus Alhambra homolog 0.0032 0.0069 0.0187
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0166 0.1475
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0027 0.0121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0124 0.0163
Loa Loa (eye worm) pax transcription factor protein 2 0.017 0.0629 0.2099
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0092 0.0315 0.0436
Schistosoma mansoni ran 0.0021 0.0025 0.0022
Brugia malayi hypothetical protein 0.0028 0.0054 0.018
Entamoeba histolytica hypothetical protein 0.0092 0.0315 0.2726
Plasmodium falciparum thioredoxin reductase 0.0061 0.0186 0.8677
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0049 0.0162
Plasmodium falciparum heat shock protein 90 0.0067 0.0213 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0194 0.0727 0.0717
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0166 0.769
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0155 0.0518
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0139 0.0183
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0076 0.0253
Entamoeba histolytica heat shock protein 90, putative 0.0067 0.0213 0.1813
Toxoplasma gondii heat shock protein 90, putative 0.0067 0.0213 0.1891
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0148 0.0689
Brugia malayi MH1 domain containing protein 0.0027 0.0049 0.0162
Plasmodium vivax glutathione reductase, putative 0.0061 0.0186 0.8677
Echinococcus multilocularis dna polymerase eta 0.0057 0.017 0.016
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.0362 0.0352
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0166 0.1186
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0066 0.0221
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0101 0.0091
Schistosoma mansoni patched 1 0.0089 0.0303 0.0418
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0049 0.0162
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.007 0.0621
Plasmodium falciparum thioredoxin reductase 0.0021 0.0026 0.0757
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0056
Loa Loa (eye worm) blistered cuticle protein 3 0.0033 0.0076 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0027 0.0088
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.1175 0.3923
Plasmodium vivax hypothetical protein, conserved 0.002 0.002 0.0467
Onchocerca volvulus 0.0025 0.0042 0.0095
Echinococcus granulosus lysosomal alpha glucosidase 0.0055 0.0163 0.0219
Trichomonas vaginalis rotamase, putative 0.0033 0.0073 0.0375
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0151 0.0552 0.1841
Brugia malayi hypothetical protein 0.0033 0.0076 0.0253
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0092 0.0315 0.0306
Brugia malayi jmjC domain containing protein 0.0051 0.0147 0.0489
Echinococcus multilocularis peregrin 0.0036 0.0088 0.0078
Brugia malayi heat shock protein 90 0.0067 0.0213 0.0711
Schistosoma mansoni lamin 0.0028 0.0053 0.0062
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0034 0.0217
Echinococcus multilocularis snurportin 1 0.0304 0.1175 0.1166
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0042 0.0139
Brugia malayi hypothetical protein 0.0036 0.0086 0.0287
Onchocerca volvulus 0.0028 0.0053 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0194 0.0729 0.2593
Echinococcus multilocularis microtubule associated protein 2 0.0745 0.2964 0.2957
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0066 0.059
Schistosoma mansoni hypothetical protein 0.174 0.7007 1
Brugia malayi ecdysone receptor 0.0025 0.0042 0.0139
Plasmodium falciparum phd finger protein, putative 0.0032 0.0069 0.2903
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0027 0.0024
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0056 0.0497
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0042 0.0139
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0274 0.0914
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0533
Loa Loa (eye worm) hypothetical protein 0.0054 0.0161 0.0537
Echinococcus multilocularis cpg binding protein 0.0163 0.0602 0.0593
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0166 0.1186
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0155 0.0145
Schistosoma mansoni transcription factor LCR-F1 0.0092 0.0315 0.0436
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0054 0.0063
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0234 0.2
Echinococcus multilocularis tumor protein p63 0.0238 0.0907 0.0898
Echinococcus multilocularis protein patched 0.0089 0.0303 0.0293
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.0455
Loa Loa (eye worm) DR-78 0.0025 0.0042 0.0139
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Loa Loa (eye worm) hypothetical protein 0.0057 0.017 0.0566
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0027 0.0062
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0073 0.0243
Echinococcus granulosus dna polymerase eta 0.0057 0.017 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0081 0.0413
Entamoeba histolytica hypothetical protein 0.0092 0.0315 0.2726
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0042 0.0045
Onchocerca volvulus 0.0082 0.0274 0.0873
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0533
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0162
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0204 0.0682
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.0455
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0034 0.0176
Brugia malayi intermediate filament protein 0.0028 0.0053 0.0178
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0088 0.0779
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0027 0.0162
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0155 0.0208
Schistosoma mansoni hypothetical protein 0.014 0.0511 0.0716
Schistosoma mansoni hypothetical protein 0.0086 0.0289 0.0399
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0034 0.0217
Brugia malayi MH1 domain containing protein 0.0027 0.0049 0.0162
Onchocerca volvulus 0.0021 0.0027 0.0044
Onchocerca volvulus 0.017 0.0629 0.2064
Brugia malayi Bromodomain containing protein 0.0077 0.0253 0.0844
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0234 0.165
Schistosoma mansoni zinc finger protein 0.0025 0.0042 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0155 0.0518
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0017 0.001 0.0052
Echinococcus multilocularis muscleblind protein 1 0.0623 0.247 0.2463
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.0101 0.071
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0023
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0154 0.0564 0.2796
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0059 0.04
Loa Loa (eye worm) hypothetical protein 0.0049 0.0139 0.0462
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0077 0.0254 0.0846
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0206 0.0688
Loa Loa (eye worm) hypothetical protein 0.0208 0.0784 0.2618
Plasmodium falciparum endoplasmin, putative 0.0041 0.0108 0.4803
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0155 0.0208
Brugia malayi tailless protein 0.0025 0.0042 0.0139
Schistosoma mansoni bromodomain containing protein 0.0136 0.0492 0.0689
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0021 0.0026 0.0057
Echinococcus granulosus dnaJ subfamily B 0.174 0.7007 1
Loa Loa (eye worm) hypothetical protein 0.0752 0.2996 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0059 0.04
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Schistosoma mansoni hypothetical protein 0.0065 0.0204 0.0278
Echinococcus granulosus lysine specific demethylase 5A 0.0051 0.0147 0.0195
Brugia malayi MH2 domain containing protein 0.0027 0.0049 0.0162
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0139 0.0129
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0155 0.0145
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0205 0.1821
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0027 0.0236
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0689 0.2738 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0234 0.0769
Trypanosoma cruzi lanosterol synthase, putative 0.0019 0.0017 0.0092
Echinococcus granulosus Niemann Pick C1 protein 0.0208 0.0784 0.1107
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0234 0.108
Echinococcus granulosus intermediate filament protein 0.0028 0.0053 0.0062
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Brugia malayi nuclear receptor RXR 0.0025 0.0042 0.0139
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0021 0.0026 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0155 0.0208
Echinococcus granulosus lamin dm0 0.0028 0.0053 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0088
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0234 0.0769
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0027 0.0004
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0101 0.013
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0042 0.0139
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0069 0.0613
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0054 0.0158 0.1085
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0042 0.0139
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0027 0.0062
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0155 0.0208
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0021 0.0026 0.0757
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.0495 0.1949 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0034 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0155 0.0518
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0435 0.1708 0.5701
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0194 0.0729 0.2593
Echinococcus granulosus geminin 0.076 0.3024 0.4308
Schistosoma mansoni hypothetical protein 0.076 0.3024 0.4308
Leishmania major heat shock protein, putative 0.0028 0.0052 0.0309
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0027 0.0023
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0025 0.0752
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0155 0.0208
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0139
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0025 0.0752
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Echinococcus granulosus peroxidasin 0.0033 0.0076 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0234 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0303 0.0293
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0234 0.0769
Echinococcus granulosus dna polymerase kappa 0.0029 0.0059 0.007
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.002 0.0467
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0155 0.0145
Echinococcus granulosus expressed conserved protein 0.0195 0.0733 0.1033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0069 0.023
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.113 0.5792
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0059 0.04
Leishmania major hypothetical protein, conserved 0.0056 0.0166 0.1149
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0079 0.0404
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0059 0.04
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0025 0.0084
Schistosoma mansoni hypothetical protein 0.076 0.3024 0.4308
Plasmodium falciparum glutathione reductase 0.0061 0.0186 0.8677
Loa Loa (eye worm) heat shock protein 75 0.0028 0.0052 0.0173
Echinococcus granulosus Niemann Pick C1 protein 0.0297 0.1147 0.1624
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0088 0.0611
Echinococcus multilocularis endoplasmin 0.0054 0.0158 0.0148
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.008 0.0099
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.0082 0.0102
Schistosoma mansoni intermediate filament proteins 0.0028 0.0053 0.0062
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0053 0.0178
Brugia malayi Thioredoxin reductase 0.0061 0.0186 0.0621
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0124 0.0114
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0155 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0145 0.0529 0.2714
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.018
Schistosoma mansoni heat shock protein 0.0067 0.0213 0.029
Schistosoma mansoni nuclear receptor 0.0025 0.0042 0.0045
Schistosoma mansoni heat shock protein 0.0067 0.0213 0.029
Echinococcus multilocularis lamin 0.0028 0.0053 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0155 0.0208
Loa Loa (eye worm) hypothetical protein 0.0185 0.069 0.2304
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0021 0.0026 0.0154
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0155 0.0208
Schistosoma mansoni kinase 0.0149 0.0545 0.0765
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0616 0.4462
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0205 0.0195
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0155 0.0208
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0029 0.0059 0.0197
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0139 0.0184
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0185 0.1324
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0042 0.0045
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0234 0.1135
Plasmodium vivax heat shock protein 86, putative 0.0067 0.0213 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0205 0.0279
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0101 0.0091
Giardia lamblia Prenyltransferase 0.0017 0.001 0.009
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0019 0.0017 0.0012
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.0495 0.1949 1
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0014 0.0071
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0234 0.165
Schistosoma mansoni DNA polymerase eta 0.0057 0.017 0.0228
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0113
Echinococcus granulosus expressed protein 0.0033 0.0073 0.009
Schistosoma mansoni myst-related protein 0.0022 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Brugia malayi mbt repeat family protein 0.0049 0.0139 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Trypanosoma brucei heat shock protein 90, putative 0.0067 0.0213 0.153
Mycobacterium tuberculosis Conserved hypothetical protein 0.0029 0.0059 0.023
Onchocerca volvulus Peroxidase homolog 0.0033 0.0076 0.021
Onchocerca volvulus 0.0021 0.0027 0.0044
Schistosoma mansoni zinc finger protein 0.0048 0.0135 0.0179
Schistosoma mansoni hypothetical protein 0.0065 0.0204 0.0278
Schistosoma mansoni rotamase 0.0033 0.0073 0.009
Onchocerca volvulus 0.0065 0.0205 0.0644
Loa Loa (eye worm) glutathione reductase 0.0061 0.0186 0.0621
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0158 0.1123
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0049 0.0055
Onchocerca volvulus 0.0028 0.0053 0.0134
Entamoeba histolytica serine/threonine protein kinase, putative 0.0293 0.113 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0025 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.04
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0017 0.001 0.0052
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0076 0.0253
Brugia malayi mbt repeat family protein 0.0049 0.0139 0.0462
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0004 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0042 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0186 0.1333
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.0163 0.0153
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0026 0.0154
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0054 0.0159 0.0149
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.113 0.8253
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0345 0.0335
Schistosoma mansoni cpg binding protein 0.0163 0.0602 0.0846
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0213 0.1093
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0155 0.0476
Leishmania major hypothetical protein, conserved 0.0031 0.0065 0.0406
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Loa Loa (eye worm) heat shock protein 90 0.0067 0.0213 0.0711
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0234 0.0769
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0027 0.0808
Mycobacterium tuberculosis Probable reductase 0.0138 0.0501 0.2517
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0204 0.0278
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.016 0.7376
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.0085 0.0107
Schistosoma mansoni myst-related protein 0.0022 0.0028 0.0026
Plasmodium falciparum zinc finger protein, putative 0.0022 0.0028 0.088
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0204 0.0278
Schistosoma mansoni hypothetical protein 0.0298 0.115 0.163
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0053 0.0178
Trichomonas vaginalis endoplasmin, putative 0.0041 0.0108 0.0552
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0027 0.0062
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0054 0.0159 0.0213
Onchocerca volvulus 0.0033 0.0076 0.021
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0066 0.0268
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0088
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0246 0.0941 0.1331
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0052 0.2065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0155 0.0145
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0293 0.113 0.8246
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0079 0.0404
Brugia malayi SET domain containing protein 0.0018 0.0013 0.0044
Onchocerca volvulus 0.0021 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.025 0.0957 0.3193
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0166 0.0616 0.4485
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0021 0.0026 0.0085
Onchocerca volvulus 0.0025 0.0042 0.0095
Trichomonas vaginalis mercuric reductase, putative 0.0021 0.0026 0.0131
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0018 0.0014 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0155 0.0518
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0027 0.0136
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0026 0.0154
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0234 0.108
Loa Loa (eye worm) DnaJ domain-containing protein 0.0019 0.0018 0.0061
Echinococcus granulosus mitogen activated protein kinase 0.0018 0.0014 0.0005
Echinococcus granulosus microtubule associated protein 2 0.0745 0.2964 0.4222
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0253
Schistosoma mansoni lamin 0.0028 0.0053 0.0062
Loa Loa (eye worm) hypothetical protein 0.0623 0.247 0.8246
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0139 0.0128
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0029 0.0059 0.023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0029 0.0059 0.0303
Schistosoma mansoni hypothetical protein 0.0031 0.0065 0.0079
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0027 0.0062
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0533
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0042 0.0032
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0066 0.0221
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0081 0.3469
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0055 0.0163 0.0544
Giardia lamblia Kinase, CMGC MAPK 0.0018 0.0014 0.0123
Onchocerca volvulus 0.0151 0.0552 0.1805
Trypanosoma brucei unspecified product 0.002 0.0022 0.013
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0155 0.0518
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0069 0.2903
Loa Loa (eye worm) hypothetical protein 0.0072 0.0234 0.0781
Schistosoma mansoni Smad4 0.0027 0.0049 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0234 0.0781
Onchocerca volvulus 0.0495 0.195 0.6495
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.016 0.0751
Onchocerca volvulus Peroxidasin homolog 0.0033 0.0076 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0015 0.0075
Schistosoma mansoni hypothetical protein 0.0065 0.0204 0.0278
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0204 0.0194
Leishmania major heat shock protein 83-1 0.0067 0.0213 0.1495
Entamoeba histolytica hypothetical protein 0.0092 0.0315 0.2726
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0081 0.3469
Schistosoma mansoni coup transcription factor 0.0053 0.0155 0.0208
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0274 0.0377
Loa Loa (eye worm) hypothetical protein 0.0082 0.0273 0.0911
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0155 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0014 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0234 0.032
Brugia malayi nuclear receptor NHR-88 0.0053 0.0155 0.0518
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0004
Loa Loa (eye worm) hypothetical protein 0.014 0.0511 0.1704
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0027 0.0808
Loa Loa (eye worm) hypothetical protein 0.0206 0.0775 0.2586
Trichomonas vaginalis hypothetical protein 0.0018 0.0015 0.0075
Trypanosoma brucei heat shock protein, putative 0.0067 0.0213 0.153
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0017 0.001 0.009
Schistosoma mansoni smad1 5 8 and 0.0027 0.0049 0.0055
Brugia malayi Bromodomain containing protein 0.0159 0.0588 0.1961
Onchocerca volvulus 0.0033 0.0076 0.021
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0069 0.023
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0034 0.0039
Onchocerca volvulus 0.0035 0.0082 0.0229
Echinococcus multilocularis Smad4 0.0027 0.0049 0.0038
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0066 0.0455
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0079 0.0404
Brugia malayi nuclear receptor RXR 0.0028 0.0054 0.018

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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