Detailed information for compound 166248

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 397.231 | Formula: C13H14Cl2N2O6S
  • H donors: 3 H acceptors: 6 LogP: 0.66 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(C(C1O)O)n1c2cc(Cl)c(cc2nc1S(=O)(=O)C)Cl
  • InChi: 1S/C13H14Cl2N2O6S/c1-24(21,22)13-16-7-2-5(14)6(15)3-8(7)17(13)12-11(20)10(19)9(4-18)23-12/h2-3,9-12,18-20H,4H2,1H3
  • InChiKey: FGKVHIWRQYXTOC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0007 0.0005 0.0008
Schistosoma mansoni ryanodine receptor related 0.0007 0.0005 0.0008
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0038 0.0281 0.0449
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0064 0.0517 0.0692
Schistosoma mansoni ferritin 0.0008 0.0017 0.0026
Mycobacterium tuberculosis Probable esterase LipL 0.003 0.0213 0.041
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0521 0.0831
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0019 0.0005
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0019 0.0002
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0019 0.0002
Echinococcus granulosus sodium leak channel non selective protein 0.0007 0.0005 0.0008
Echinococcus granulosus voltage dependent calcium channel 0.0007 0.0005 0.0008
Trypanosoma cruzi importin beta-1 subunit, putative 0.0021 0.0135 0.2623
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0007 0.0005 0.0021
Schistosoma mansoni hypothetical protein 0.0048 0.0373 0.0596
Echinococcus granulosus potassium large conductance calcium activated 0.0007 0.0005 0.0008
Schistosoma mansoni inositol monophosphatase 0.0053 0.0416 0.0665
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0019 0.0118 0.0118
Echinococcus granulosus lamin dm0 0.0031 0.0218 0.0348
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0007 0.0005 0.0007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0218 0.0863
Brugia malayi mbt repeat family protein 0.0038 0.0281 0.1238
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.0168
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0043 0.0326 0.6317
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0008 0.0019 0.0002
Schistosoma mansoni transient receptor potential channel 0.0007 0.0005 0.0008
Echinococcus multilocularis SAM and MBT domain containing protein 0.0038 0.0281 0.0377
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Brugia malayi cation channel family protein 0.0007 0.0005 0.0021
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0053 0.0416 0.8041
Echinococcus granulosus SAM and MBT domain containing protein 0.0038 0.0281 0.0449
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0053 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0007 0.0005 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Brugia malayi MH2 domain containing protein 0.0118 0.1007 0.443
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0019 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0036 0.0271 0.0433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Schistosoma mansoni inositol monophosphatase 0.0053 0.0416 0.0665
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0168 0.0168
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0075 0.0616 0.2476
Schistosoma mansoni hypothetical protein 0.0281 0.2474 0.3949
Brugia malayi TAR-binding protein 0.0064 0.0521 0.2291
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Mycobacterium tuberculosis Conserved protein 0.003 0.0213 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0106 0.2048
Echinococcus multilocularis geminin 0.0703 0.6265 0.8396
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0007 0.0005 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0075 0.0616 0.0983
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0106 0.0089
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0007 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0007 0.0005 0.0022
Leishmania major cathepsin L-like protease 0.0012 0.0053 0.0948
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0281 0.0449
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0008 0.0017 0.0049
Echinococcus granulosus histone acetyltransferase MYST2 0.0043 0.0328 0.0524
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0041 0.0065
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0019 0.0118 0.0113
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0681 0.1086
Echinococcus granulosus GPCR family 2 0.0082 0.0681 0.1086
Leishmania major cathepsin L-like protease 0.0047 0.0363 0.6993
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0019 0.0368
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0283 0.5484
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0019 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0041 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0041 0.0146
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.054 0.4803 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0007 0.0005 0.0007
Trypanosoma cruzi cruzipain precursor, putative 0.0047 0.0363 0.7022
Echinococcus multilocularis Smad4 0.0008 0.0016 0.0021
Echinococcus granulosus short transient receptor potential channel 6 0.0007 0.0005 0.0008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0007 0.0005 0.0008
Echinococcus multilocularis conserved hypothetical protein 0.0007 0.0005 0.0007
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0007 0.0005 0.0008
Brugia malayi MH1 domain containing protein 0.0008 0.0016 0.0069
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0842
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1118 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0053 0.0238
Giardia lamblia Kinase, PLK 0.0064 0.0517 1
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0027 0.0036
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0041 0.0065
Onchocerca volvulus 0.0031 0.0218 0.0953
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0012 0.0053 0.0196
Schistosoma mansoni two-pore calcium channel 0.0007 0.0005 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0007 0.0005 0.0007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0041 0.0146
Echinococcus granulosus smad 0.0008 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Echinococcus granulosus Smad4 0.0008 0.0016 0.0025
Leishmania major hypothetical protein, conserved 0.0025 0.0168 0.3187
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0041 0.0055
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0019 0.0002
Toxoplasma gondii exonuclease III APE 0.0018 0.0106 0.0101
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0019 0.0005
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0076 0.0102
Brugia malayi Calcitonin receptor-like protein seb-1 0.0259 0.2273 1
Echinococcus granulosus polycomb protein SCMH1 0.0038 0.0281 0.0449
Leishmania major cytochrome p450-like protein 0.0008 0.0019 0.0276
Echinococcus multilocularis sodium channel protein 0.0007 0.0005 0.0007
Mycobacterium leprae conserved hypothetical protein 0.003 0.0213 0.0197
Echinococcus multilocularis snurportin 1 0.0281 0.2474 0.3315
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0053 0.0416 0.8059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0075 0.0616 0.0983
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0041 0.0146
Echinococcus granulosus importin subunit beta 1 0.0026 0.018 0.0288
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0521 0.0698
Schistosoma mansoni hypothetical protein 0.0082 0.0681 0.1086
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0076 0.0121
Brugia malayi ecdysteroid receptor 0.0011 0.0041 0.018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0053 0.0196
Echinococcus multilocularis smad 0.0008 0.0016 0.0021
Echinococcus granulosus hyperpolarization activated cyclic 0.0007 0.0005 0.0008
Plasmodium vivax vivapain-2 0.0012 0.0053 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0019 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0071 0.0267
Loa Loa (eye worm) inositol-1 0.0053 0.0416 0.1667
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0019 0.0118 0.0158
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0681 0.2994
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0007 0.0005 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0041 0.018
Echinococcus granulosus two pore calcium channel protein 2 0.0007 0.0005 0.0008
Schistosoma mansoni hypothetical protein 0.0232 0.2031 0.3242
Toxoplasma gondii cathepsin CPL 0.0012 0.0053 0.0049
Echinococcus multilocularis two pore calcium channel protein 1 0.0007 0.0005 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0041 0.0065
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0041 0.0055
Schistosoma mansoni lamin 0.0031 0.0218 0.0348
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1118 1 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0007 0.0005 0.0008
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1118 1 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0016 0.0025
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0373 0.1641
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi Cytochrome P450 family protein 0.0039 0.0291 0.128
Leishmania major cathepsin L-like protease 0.0012 0.0053 0.0948
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0238 0.038
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0041 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Schistosoma mansoni calcium-activated potassium channel 0.0007 0.0005 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0007 0.0005 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Schistosoma mansoni intermediate filament proteins 0.0031 0.0218 0.0348
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0363 0.7022
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0019 0.0005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0019 0.0118 0.2279
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.5253
Schistosoma mansoni coup transcription factor 0.0011 0.0041 0.0065
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0053 0.1033
Brugia malayi MH2 domain containing protein 0.0008 0.0016 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0041 0.018
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0007 0.0005 0.0008
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0007 0.0005 0.0008
Brugia malayi Cathepsin L-like precursor 0.0008 0.0017 0.0075
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0053 0.0072
Echinococcus granulosus muscleblind protein 0.0109 0.092 0.1469
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.00000017748
Echinococcus granulosus potassium voltage gated channel protein 0.0007 0.0005 0.0008
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0007 0.0005 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0019 0.0005
Loa Loa (eye worm) hypothetical protein 0.0234 0.2051 0.8287
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0213 0.4124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0041 0.0065
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0019 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Mycobacterium leprae putative cytochrome p450 0.0008 0.0019 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0019 0.0368
Brugia malayi beta-lactamase family protein 0.003 0.0213 0.0937
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0019 0.0368
Loa Loa (eye worm) hypothetical protein 0.0259 0.2273 0.9189
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0007 0.0005 0.0008
Schistosoma mansoni hypothetical protein 0.0007 0.0005 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0075 0.0616 0.0983
Schistosoma mansoni microtubule-associated protein tau 0.0502 0.4455 0.7112
Echinococcus granulosus potassium voltage gated channel protein 0.0007 0.0005 0.0008
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0019 0.0002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0041 0.0055
Brugia malayi CXXC zinc finger family protein 0.0033 0.0236 0.1037
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0007 0.0005 0.0021
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0071
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0007 0.0005 0.0021
Echinococcus granulosus two pore calcium channel protein 1 0.0007 0.0005 0.0008
Echinococcus multilocularis potassium large conductance calcium activated 0.0007 0.0005 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.018 0.0711
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0019 0.0005
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0019 0.0118 0.0457
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0106 0.0472
Echinococcus multilocularis inositol monophosphatase 1 0.0053 0.0416 0.0558
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0521 0.0831
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0019 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0007 0.0005 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0041 0.018
Echinococcus granulosus microtubule associated protein 2 0.0502 0.4455 0.7112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0027 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0213 0.4124
Brugia malayi Muscleblind-like protein 0.0109 0.092 0.4047
Echinococcus granulosus dnaJ subfamily B 0.0463 0.4108 0.6558
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0508 0.0503
Schistosoma mansoni transient receptor potential channel 0.0007 0.0005 0.0008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0041 0.0055
Mycobacterium tuberculosis Conserved protein 0.003 0.0213 0.041
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0019 0.0002
Plasmodium falciparum importin beta, putative 0.0026 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus granulosus intermediate filament protein 0.0031 0.0218 0.0348
Echinococcus multilocularis microtubule associated protein 2 0.0502 0.4455 0.5971
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0227 0.1014
Brugia malayi hypothetical protein 0.0016 0.0088 0.0388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0281 0.112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Echinococcus multilocularis calcium activated potassium channel 0.0007 0.0007 0.0009
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0053 0.0217
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0041 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0075 0.0616 0.0983
Leishmania major cytochrome p450-like protein 0.0008 0.0019 0.0276
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1118 1 1
Echinococcus multilocularis transfer RNA-Gly 0.0007 0.0005 0.0007
Onchocerca volvulus 0.0012 0.0053 0.0217
Loa Loa (eye worm) hypothetical protein 0.0109 0.092 0.3707
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Plasmodium vivax hypothetical protein, conserved 0.003 0.0213 0.0213
Brugia malayi Cathepsin L-like precursor 0.0008 0.0017 0.0075
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0007 0.0005 0.0008
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0016 0.0025
Schistosoma mansoni ferritin light chain 0.0008 0.0017 0.0026
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0007 0.0005 0.0021
Entamoeba histolytica cysteine protease, putative 0.0012 0.0053 0.1033
Schistosoma mansoni hypothetical protein 0.0082 0.0681 0.1086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0017 0.0076
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Leishmania major cysteine peptidase A (CPA) 0.0012 0.0053 0.0948
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0041 0.0162
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0041 0.018
Brugia malayi Pre-SET motif family protein 0.0033 0.0238 0.1048
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0019 0.0368
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0019 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.1007 0.406
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0118 0.2279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.2051 0.3273
Brugia malayi Inositol-1 0.0053 0.0416 0.1831
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0517 0.0825
Entamoeba histolytica serine/threonine protein kinase, putative 0.0064 0.0517 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0007 0.0005 0.0021
Echinococcus granulosus inositol monophosphatase 1 0.0053 0.0416 0.0665
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0106 0.0169
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0007 0.0005 0.0008
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.009 0.0398
Echinococcus granulosus transient receptor potential gamma protein 0.0007 0.0005 0.0008
Echinococcus multilocularis cysteine protease 0.0012 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Mycobacterium leprae Probable lipase LipE 0.003 0.0213 0.0197
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0053 0.1033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.001 0.0043
Loa Loa (eye worm) ctsf protein 0.0012 0.0053 0.0196
Schistosoma mansoni ferritin 0.0008 0.0017 0.0026
Echinococcus granulosus cathepsin l1 0.0008 0.0017 0.0027
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0238 0.0234
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.003 0.0213 0.0937
Echinococcus granulosus TRP transient receptor potential channel 0.0007 0.0005 0.0008
Schistosoma mansoni lamin 0.0031 0.0218 0.0348
Brugia malayi Cytochrome P450 family protein 0.0008 0.0019 0.0083
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0019 0.0002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0019 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0027 0.0036
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0007 0.0005 0.0008
Loa Loa (eye worm) Smad1 0.0008 0.0016 0.0044
Loa Loa (eye worm) cytochrome P450 0.0008 0.0019 0.0057
Echinococcus multilocularis sodium leak channel non selective protein 0.0007 0.0005 0.0007
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0019 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0041 0.018
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0007 0.0005 0.0021
Entamoeba histolytica hypothetical protein 0.0021 0.0135 0.2623
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0019 0.0276
Trichomonas vaginalis set domain proteins, putative 0.0255 0.224 1
Echinococcus multilocularis voltage gated potassium channel 0.0007 0.0005 0.0007
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0007 0.0005 0.0008
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0019 0.0057
Mycobacterium tuberculosis Probable lipase LipE 0.003 0.0213 0.041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0007 0.0005 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0227 0.1014
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0836 0.7462 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0271 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0041 0.018
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0213 0.034
Schistosoma mansoni voltage-dependent calcium channel 0.0007 0.0005 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.003 0.0213 0.0285
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0238 0.038
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0019 0.0002
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0007 0.0005 0.0094
Onchocerca volvulus 0.0048 0.0373 0.1648
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0007 0.0005 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0041 0.0146
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0135 0.0605
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0007 0.0005 0.0021
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0218 0.0863
Leishmania major cathepsin L-like protease 0.0012 0.0053 0.0948
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0053 0.1033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0259 0.2273 0.9189
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0041 0.0162
Leishmania major cytochrome p450-like protein 0.0008 0.0019 0.0276
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.003 0.0213 0.0843
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0053 0.0416 0.04
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0213 0.0951
Brugia malayi Transient-receptor-potential like protein 0.0007 0.0005 0.0021
Schistosoma mansoni smad1 5 8 and 0.0008 0.0016 0.0025
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0019 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis muscleblind protein 0.0109 0.092 0.1233
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0012 0.0053 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0007 0.0005 0.0007
Brugia malayi Augmenter of liver regeneration 0.0038 0.0283 0.1246
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0041 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0574 0.0917
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1118 1 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0019 0.0002
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Echinococcus granulosus hyperpolarization activated cyclic 0.0007 0.0005 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0106 0.0472
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0053 0.0072
Leishmania major cathepsin L-like protease 0.0047 0.0363 0.6993
Schistosoma mansoni hypothetical protein 0.0177 0.1536 0.2452
Trypanosoma cruzi polo-like protein kinase, putative 0.0064 0.0517 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0007 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0283 0.0279
Loa Loa (eye worm) beta-lactamase 0.003 0.0213 0.0843
Schistosoma mansoni cpg binding protein 0.0033 0.0236 0.0376
Brugia malayi latrophilin 2 splice variant baaae 0.0177 0.1536 0.6757
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0218 0.0863
Schistosoma mansoni importin beta-1 0.0026 0.018 0.0288
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0007 0.0005 0.0007
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0016 0.0044
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0053 0.0416 0.04
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0283 0.5484
Trypanosoma brucei cytochrome P450, putative 0.0008 0.0019 0.0368
Loa Loa (eye worm) RNA binding protein 0.0064 0.0521 0.209
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Schistosoma mansoni hypothetical protein 0.0463 0.4108 0.6558
Schistosoma mansoni hypothetical protein 0.0703 0.6265 1
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Echinococcus multilocularis voltage gated potassium channel 0.0007 0.0005 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0041 0.018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0238 0.0319
Echinococcus multilocularis short transient receptor potential channel 6 0.0007 0.0005 0.0007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0007 0.0005 0.0021
Mycobacterium ulcerans lipase LipD 0.003 0.0213 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0681 0.0912
Echinococcus multilocularis histone acetyltransferase MYST2 0.0043 0.0328 0.044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0168 0.066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0075 0.0616 0.271
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0152 0.1308 0.1753
Echinococcus multilocularis ferritin 0.0008 0.0017 0.0022
Echinococcus multilocularis polycomb protein SCMH1 0.0038 0.0281 0.0377
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0053 0.0416 0.1858
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0041 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0071 0.0267
Echinococcus granulosus beta LACTamase domain containing family member 0.003 0.0213 0.034
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0283 0.5484
Brugia malayi nuclear hormone receptor 0.0011 0.0041 0.018
Leishmania major cathepsin L-like protease 0.0012 0.0053 0.0948
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0016 0.0025
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0106 0.0106
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.003 0.0213 0.0197
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0041 0.0065
Trypanosoma cruzi major cysteine proteinase, putative 0.0037 0.0273 0.5284
Schistosoma mansoni cpg binding protein 0.0034 0.0252 0.0403
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0118 0.2279
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0213 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus granulosus ryanodine receptor 44f 0.0007 0.0005 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0291 0.1159
Onchocerca volvulus 0.0012 0.0053 0.0217
Onchocerca volvulus 0.003 0.0213 0.0931
Toxoplasma gondii HEAT repeat-containing protein 0.0026 0.018 0.0176
Echinococcus multilocularis voltage dependent calcium channel 0.0007 0.0005 0.0007
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0019 0.0005
Echinococcus granulosus cathepsin l1 0.0012 0.0053 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0041 0.0065
Schistosoma mansoni hypothetical protein 0.0082 0.0681 0.1086
Schistosoma mansoni ran 0.0019 0.0118 0.0188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0041 0.0146
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0019 0.0002
Mycobacterium ulcerans beta-lactamase 0.003 0.0213 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Echinococcus multilocularis importin subunit beta 1 0.0026 0.018 0.0242
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.018 0.3491
Onchocerca volvulus 0.0031 0.0218 0.0953
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0521 0.0831
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0041 0.0065
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.3251
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0053 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus granulosus voltage gated potassium channel 0.0007 0.0005 0.0008
Echinococcus granulosus lamin 0.0031 0.0218 0.0348
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0053 0.0416 0.8059
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0064 0.0517 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0192 0.1666 0.3447
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0019 0.0005
Schistosoma mansoni survival motor neuron protein 0.0048 0.0373 0.0596
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.00000017748
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0053 0.0416 0.8059
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0053 0.0217
Brugia malayi Pre-SET motif family protein 0.0224 0.1962 0.863
Loa Loa (eye worm) hypothetical protein 0.0082 0.0681 0.2737
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0213 0.4124
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Echinococcus multilocularis hyperpolarization activated cyclic 0.0007 0.0005 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0007 0.0005 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Echinococcus multilocularis potassium voltage gated channel protein 0.0007 0.0005 0.0007
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0007 0.0005 0.0008
Onchocerca volvulus 0.0255 0.224 1
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0007 0.0005 0.0008
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0007 0.0005 0.0021
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0038 0.0281 0.1237
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0019 0.0005
Plasmodium vivax importin-beta 2, putative 0.0026 0.018 0.018
Brugia malayi Cytochrome P450 family protein 0.0008 0.0019 0.0083
Loa Loa (eye worm) hypothetical protein 0.0043 0.0328 0.1309
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0041 0.0065
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0019 0.0014
Plasmodium vivax vivapain-2 0.0012 0.0053 0.0053
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0106 0.0089
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Plasmodium falciparum cysteine proteinase falcipain 3 0.0012 0.0053 0.0053
Echinococcus multilocularis short transient receptor potential channel 6 0.0007 0.0005 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0053 0.0416 0.1858
Echinococcus granulosus voltage gated potassium channel 0.0007 0.0005 0.0008
Echinococcus granulosus voltage gated hydrogen channel 1 0.0007 0.0005 0.0008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0271 0.0364
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0064 0.0517 0.2073
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0521 0.209
Schistosoma mansoni Smad4 0.0008 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0053 0.0238
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0007 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0076 0.0287
Schistosoma mansoni apoferritin-2 0.0008 0.0017 0.0026
Echinococcus multilocularis potassium voltage gated channel protein 0.0007 0.0005 0.0007
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0019 0.0118 0.0291
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Loa Loa (eye worm) fibroinase 0.0012 0.0053 0.0196
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0007 0.0005 0.0008
Schistosoma mansoni cathepsin F (C01 family) 0.0008 0.0017 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi hypothetical protein 0.0007 0.0005 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0007 0.0005 0.0007
Echinococcus granulosus ferritin 0.0008 0.0017 0.0026
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0168 0.3251
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0213 0.034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0236 0.0935
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Leishmania major GTP-binding protein, putative 0.0019 0.0118 0.2206
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0106 0.0409
Loa Loa (eye worm) mbt repeat family protein 0.0038 0.0281 0.112
Brugia malayi cathepsin L-like precursor 0.0008 0.0017 0.0075
Mycobacterium tuberculosis Probable hydrolase 0.003 0.0213 0.041
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0053 0.0416 0.0412
Onchocerca volvulus 0.0012 0.0053 0.0217
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0019 0.0005
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0019 0.003
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0106 0.0465
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.5253
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0283 0.5484
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0283 0.0283
Echinococcus granulosus potassium voltage gated channel protein 0.0007 0.0005 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0041 0.018
Schistosoma mansoni transient receptor potential channel 0.0007 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Brugia malayi hypothetical protein 0.0234 0.2051 0.902
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0168 0.0163
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0019 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0019 0.0005
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0007 0.0005 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.001 0.0043
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0007 0.0005 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0106 0.2048
Loa Loa (eye worm) hypothetical protein 0.0177 0.1536 0.6203
Trichomonas vaginalis importin beta-1, putative 0.0021 0.0135 0.0605
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Schistosoma mansoni ap endonuclease 0.0018 0.0106 0.0169
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0038 0.0283 0.038
Schistosoma mansoni transient receptor potential channel 4 0.0007 0.0005 0.0008
Loa Loa (eye worm) MBCTL1 0.0043 0.0328 0.1309
Schistosoma mansoni ferritin 0.0008 0.0017 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Onchocerca volvulus 0.0033 0.0238 0.1044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0041 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0019 0.0005
Onchocerca volvulus 0.0033 0.0236 0.1033
Trypanosoma brucei polo-like protein kinase 0.0064 0.0517 1
Echinococcus granulosus expressed protein 0.0008 0.0017 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0027 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0019 0.0005
Echinococcus multilocularis dnaJ subfamily B 0.0463 0.4108 0.5506
Echinococcus multilocularis potassium voltage gated channel protein 0.0007 0.0005 0.0007
Mycobacterium ulcerans esterase/lipase LipP 0.003 0.0213 0.0197
Schistosoma mansoni 60S ribosomal protein L21 0.0007 0.0005 0.0008
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0007 0.0005 0.0007
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0043 0.0328 0.1443
Brugia malayi olfactory channel protein osm-9 0.0007 0.0005 0.0021
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0213 0.0951
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0059
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0019 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0041 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis cysteine protease 0.0012 0.0053 0.0072
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0106 0.1972
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.3251
Echinococcus multilocularis lamin dm0 0.0031 0.0218 0.0292
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0007 0.0005 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0019 0.0005
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0007 0.0005 0.0021
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0106 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0106 0.0142
Echinococcus granulosus transient receptor potential cation channel 0.0007 0.0005 0.0008
Schistosoma mansoni hypothetical protein 0.0703 0.6265 1
Schistosoma mansoni cytochrome P450 0.0008 0.0019 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Brugia malayi steroid hormone receptor 0.0011 0.0041 0.018
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0019 0.0002
Echinococcus granulosus cathepsin l cysteine peptidase 0.0012 0.0053 0.0085
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0041 0.0065
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0007 0.0005 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Schistosoma mansoni smad1 5 8 and 0.0008 0.0016 0.0025
Schistosoma mansoni voltage-gated cation channel 0.0007 0.0005 0.0008
Onchocerca volvulus 0.003 0.0213 0.0931
Mycobacterium tuberculosis Conserved protein 0.003 0.0213 0.041
Schistosoma mansoni ferritin 0.0008 0.0017 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0007 0.0005 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0075 0.0616 0.0826
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0238 0.0319
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0007 0.0005 0.0094
Schistosoma mansoni hypothetical protein 0.0011 0.0044 0.007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0681 0.2994
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.003 0.0213 0.041
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0043 0.0328 0.0524
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0007 0.0005 0.0021
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0047 0.0367 0.0732
Brugia malayi Cytochrome P450 family protein 0.0008 0.0019 0.0083
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.1007 0.406
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0135 0.0605
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0044 0.0059
Loa Loa (eye worm) hypothetical protein 0.0008 0.0017 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0363 0.7022
Brugia malayi RNA, U transporter 1 0.0075 0.0617 0.2715
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0007 0.0005 0.0007
Echinococcus granulosus voltage dependent calcium channel 0.0007 0.0005 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0259 0.2273 1
Echinococcus granulosus hypothetical protein 0.0007 0.0005 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0213 0.0951
Mycobacterium tuberculosis Probable lipase LipD 0.003 0.0213 0.041
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0007 0.0005 0.0008
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0043 0.0328 0.044
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.00000017748
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0041 0.0055
Brugia malayi beta-lactamase family protein 0.003 0.0213 0.0937
Brugia malayi RNA binding protein 0.0064 0.0521 0.2291
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0007 0.0005 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0681 0.0912
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0007 0.0005 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0281 0.0449
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0041 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0019 0.0005
Echinococcus multilocularis transient receptor potential gamma protein 0.0007 0.0005 0.0007
Echinococcus multilocularis ryanodine receptor 44f 0.0007 0.0005 0.0007
Echinococcus granulosus potassium voltage gated channel protein 0.0007 0.0005 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0019 0.0368
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0007 0.0005 0.0008
Leishmania major importin beta-1 subunit, putative 0.0021 0.0135 0.2553
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0041 0.0065
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0007 0.0005 0.0008
Trypanosoma cruzi polo-like protein kinase, putative 0.0064 0.0517 1
Echinococcus granulosus calcium activated potassium channel 0.0007 0.0007 0.0011
Schistosoma mansoni smad 0.0008 0.0016 0.0025
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0053 0.0416 0.8059
Echinococcus multilocularis hyperpolarization activated cyclic 0.0007 0.0005 0.0007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0681 0.1086
Echinococcus multilocularis GPCR, family 2 0.0082 0.0681 0.0912
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.5253
Leishmania major cathepsin L-like protease 0.0012 0.0053 0.0948
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0007 0.0005 0.0021
Brugia malayi Smad1 0.0008 0.0016 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0019 0.0005
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0016 0.0021
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0007 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0213 0.0843
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0038 0.0283 0.0452
Echinococcus multilocularis 0.0008 0.0019 0.0025
Entamoeba histolytica Ran family GTPase 0.0019 0.0118 0.2279
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0106 0.2048
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.1118 1 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0007 0.0005 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0053 0.0085
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0007 0.0005 0.0021
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0016 0.0044
Echinococcus multilocularis lamin 0.0031 0.0218 0.0292
Echinococcus granulosus tar DNA binding protein 0.0064 0.0521 0.0831
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0019 0.0002
Brugia malayi hypothetical protein 0.0036 0.0271 0.1193
Echinococcus granulosus cpg binding protein 0.0034 0.0252 0.0403
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0007 0.0005 0.0094
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0017 0.0076
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.018 0.3491
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0041 0.018
Schistosoma mansoni voltage-gated ion channel 0.0007 0.0005 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0075 0.0616 0.0983
Onchocerca volvulus 0.0012 0.0053 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0041 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0041 0.018
Schistosoma mansoni ap endonuclease 0.0018 0.0106 0.0169
Brugia malayi ion channel NompC 0.0007 0.0005 0.0021
Onchocerca volvulus 0.0011 0.0041 0.0162
Brugia malayi Cathepsin L-like precursor 0.0012 0.0053 0.0235
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0041 0.0065
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi serine/threonine-protein kinase plk-2 0.0064 0.0517 0.2272
Plasmodium vivax SET domain protein, putative 0.0033 0.0238 0.0238
Schistosoma mansoni hypothetical protein 0.0082 0.0681 0.1086
Onchocerca volvulus 0.0012 0.0053 0.0217
Echinococcus granulosus GTP binding nuclear protein Ran 0.0019 0.0118 0.0188
Echinococcus granulosus geminin 0.0703 0.6265 1
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0007 0.0005 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0041 0.018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0047 0.0367 0.0351
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0007 0.0005 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0041 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0019 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0238 0.038
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1118 1 1
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.2051 0.2748
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0017 0.0329
Toxoplasma gondii ABC1 family protein 0.003 0.0213 0.0208
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0007 0.0005 0.0008
Trichomonas vaginalis helicase, putative 0.0007 0.001 0.0043
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0681 0.2737
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.1962 0.7928
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0213 0.0951
Echinococcus multilocularis muscleblind protein 1 0.0109 0.092 0.1233
Mycobacterium tuberculosis Probable conserved lipoprotein 0.003 0.0213 0.041
Brugia malayi hypothetical protein 0.0025 0.0168 0.0739
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0221 0.0353
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0007 0.0005 0.0021
Schistosoma mansoni ran 0.0019 0.0118 0.0188
Schistosoma mansoni kinase 0.0032 0.0235 0.0375
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.009 0.0346
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0517 0.2306
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0019 0.0005
Onchocerca volvulus Cathepsin F homolog 0.0012 0.0053 0.0217
Brugia malayi MH2 domain containing protein 0.0008 0.0016 0.0069
Onchocerca volvulus 0.0012 0.0053 0.0217
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0521 0.0831
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0019 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0041 0.0055
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0041 0.0065
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0041 0.018
Loa Loa (eye worm) hypothetical protein 0.0008 0.0017 0.0049
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0044 0.007
Brugia malayi Importin beta-1 subunit 0.0026 0.018 0.0793
Leishmania major cathepsin L-like protease 0.0047 0.0363 0.6993
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.003 0.0213 0.041
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0007 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0521 0.209
Echinococcus multilocularis shaker cognate 0.0007 0.0005 0.0007
Brugia malayi Cathepsin L-like cysteine proteinase 0.0008 0.0017 0.0075
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0106 0.2048
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0152 0.1308 0.2088
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Trichomonas vaginalis esterase, putative 0.003 0.0213 0.0951
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0064 0.0517 0.0825
Brugia malayi voltage-dependent calcium channel 0.0007 0.0005 0.0021
Echinococcus multilocularis expressed protein 0.0008 0.0017 0.0022
Trichomonas vaginalis ran, putative 0.0019 0.0118 0.0526
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.5253
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0019 0.0368
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0041 0.0065
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0106 0.0186
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0041 0.0055
Schistosoma mansoni hypothetical protein 0.0008 0.0019 0.003
Echinococcus multilocularis cpg binding protein 0.0034 0.0252 0.0338
Onchocerca volvulus 0.0008 0.0017 0.0054
Brugia malayi beta-lactamase 0.003 0.0213 0.0937
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Echinococcus granulosus sodium channel protein 0.0007 0.0005 0.0008
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0041 0.0065
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0007 0.0005 0.0007
Echinococcus multilocularis musashi 0.0031 0.0218 0.0292
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Leishmania major hypothetical protein, conserved 0.003 0.0213 0.4068
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0041 0.0162
Onchocerca volvulus Serine\/threonine kinase homolog 0.0064 0.0517 0.2289
Echinococcus granulosus potassium voltage gated channel protein 0.0007 0.0005 0.0008
Schistosoma mansoni apoferritin-2 0.0008 0.0017 0.0026
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0019 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0238 0.0946
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0053 0.0072
Trichomonas vaginalis ferritin, putative 0.0008 0.0017 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Brugia malayi cytochrome P450 0.0008 0.0019 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0363 0.7022
Trichomonas vaginalis inositol monophosphatase, putative 0.0053 0.0416 0.1858
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0012 0.0053 0.0053
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0271 0.0433
Schistosoma mansoni smad1 5 8 and 0.0008 0.0016 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0238 0.038
Schistosoma mansoni myelin transcription factor 1 myt1 0.0043 0.0328 0.0524
Loa Loa (eye worm) hypothetical protein 0.0109 0.092 0.3707
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0053 0.0085
Echinococcus granulosus cathepsin L cysteine proteinase 0.0012 0.0053 0.0085
Loa Loa (eye worm) cysteine protease 0.0012 0.0053 0.0196
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0044 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.001 0.0043
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0281 0.2474 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0041 0.018
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0019 0.0118 0.0518
Echinococcus multilocularis voltage dependent calcium channel 0.0007 0.0005 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0019 0.0005
Leishmania major hypothetical protein, conserved 0.0038 0.0283 0.5441
Loa Loa (eye worm) hepatopoietin HPO2 0.0038 0.0283 0.1128
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0007 0.0005 0.0007
Onchocerca volvulus 0.0012 0.0053 0.0217
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Brugia malayi cation channel family protein 0.0007 0.0005 0.0021
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0007 0.0005 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0019 0.0057
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0283 0.0283
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0521 0.2291
Schistosoma mansoni cpg binding protein 0.0034 0.0252 0.0403
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0043 0.019
Brugia malayi mbt repeat family protein 0.0038 0.0281 0.1238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0041 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0043
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0041 0.0065
Onchocerca volvulus 0.0038 0.0281 0.1237
Echinococcus granulosus snurportin 1 0.0281 0.2474 0.3949
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0007 0.0005 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0521 0.0831
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0238 0.038
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0218 0.0958
Mycobacterium ulcerans hypothetical protein 0.003 0.0213 0.0197
Schistosoma mansoni ferritin light chain 0.0008 0.0017 0.0026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0106 0.0089
Echinococcus multilocularis two pore calcium channel protein 2 0.0007 0.0005 0.0007
Onchocerca volvulus 0.003 0.0213 0.0931
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0363 0.7022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0075 0.0616 0.0826
Loa Loa (eye worm) hypothetical protein 0.0011 0.0041 0.0146
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0041 0.0065
Brugia malayi intermediate filament protein 0.0031 0.0218 0.0958
Brugia malayi nuclear receptor NHR-88 0.0011 0.0041 0.018
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0041 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0053 0.0238
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0019 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0005 0.0008
Echinococcus granulosus shaker cognate 0.0007 0.0005 0.0008
Echinococcus granulosus short transient receptor potential channel 6 0.0007 0.0005 0.0008
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0283 0.0279
Schistosoma mansoni vesicular amine transporter 0.0007 0.0005 0.0008
Brugia malayi MH1 domain containing protein 0.0008 0.0016 0.0069
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0027 0.0042

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 10 uM Activity against human cytomegalovirus (HCMV) using plaque reduction assay ChEMBL. 8071942
IC50 (functional) = 10 uM Tested for the visual cytotoxicity on HFF cells at the time of human cytomegalovirus (HCMV) plaque enumeration ChEMBL. 8071942

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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