Detailed information for compound 1771165

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 273.222 | Formula: C11H16NO5P
  • H donors: 3 H acceptors: 5 LogP: -0.64 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N(CCCP(=O)(O)O)O)Cc1ccccc1
  • InChi: 1S/C11H16NO5P/c13-11(9-10-5-2-1-3-6-10)12(14)7-4-8-18(15,16)17/h1-3,5-6,14H,4,7-9H2,(H2,15,16,17)
  • InChiKey: XFWAXDKPSOXCDG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium berghei 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Theileria parva 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium knowlesi 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Babesia bovis 1-deoxy-D-xylulose 5-phosphate reductoisomerase family protein Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras Get druggable targets OG5_130462 All targets in OG5_130462
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium yoelii 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Neospora caninum 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Brugia malayi Protein kinase domain containing protein 0.0061 0.0343 0.0343
Brugia malayi cytokine inducible SH2-containing protein 5 0.0033 0.012 0.012
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0017 0.0044
Echinococcus granulosus beta tubulin 0.0896 0.6921 0.9425
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0896 0.6921 0.9425
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Trypanosoma brucei epsilon tubulin 0.0535 0.4079 0.5894
Echinococcus multilocularis tensin 0.0033 0.012 0.0163
Brugia malayi SH2 domain containing protein 0.0061 0.0343 0.0343
Onchocerca volvulus 0.0041 0.0187 0.0888
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0033 0.012 0.0554
Loa Loa (eye worm) alpha-tubulin 0.0669 0.5134 0.5134
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0653 0.089
Echinococcus multilocularis agrin 0.0042 0.0193 0.0263
Schistosoma mansoni tyrosine kinase 0.01 0.0653 0.0944
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0098
Leishmania major beta tubulin 0.0896 0.6921 1
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0275 0.2026 0.2922
Plasmodium vivax delta tubulin, putative 0.0231 0.1685 0.2435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0175 0.0461
Schistosoma mansoni signal transduction protein lnk-related 0.0033 0.012 0.0173
Echinococcus granulosus lamin dm0 0.003 0.0097 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0196 0.0276
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus N chimaerin 0.0033 0.012 0.0163
Loa Loa (eye worm) ctsf protein 0.0018 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.045 0.3408 0.4925
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Onchocerca volvulus 0.004 0.0175 0.0827
Schistosoma mansoni hypothetical protein 0.004 0.0175 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Plasmodium falciparum thioredoxin reductase 0.0052 0.0273 0.0394
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0066 0.0095
Loa Loa (eye worm) hypothetical protein 0.0178 0.1269 0.1269
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0017 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.0193 0.0279
Trypanosoma brucei beta tubulin 0.0896 0.6921 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0438 0.3311 0.4781
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0175 0.0253
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0032 0.0112 0.0153
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0028 0.0086 0.0125
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0416 0.0601
Echinococcus granulosus tubulin gamma 1 chain 0.0536 0.4083 0.556
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0087 0.0551 0.0551
Echinococcus granulosus fibrillin 1 0.0027 0.0079 0.0108
Entamoeba histolytica hypothetical protein 0.0026 0.0066 0.0083
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0582 0.4445 0.6053
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0033 0.012 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Giardia lamblia Tenascin precursor 0.0027 0.0079 0.0107
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0069 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis tubulin alpha 3 chain 0.0669 0.5134 0.6992
Schistosoma mansoni retinoic acid receptor RXR 0.0196 0.1405 0.203
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0175 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0086 0.0125
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0175 0.0238
Echinococcus multilocularis protein jagged 2 0.0027 0.0079 0.0108
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Leishmania major beta tubulin 0.0896 0.6921 1
Brugia malayi Raf kinase 0.0028 0.0086 0.0086
Onchocerca volvulus 0.003 0.0097 0.0439
Mycobacterium ulcerans putative regulatory protein 0.004 0.0175 0.0448
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Leishmania major hypothetical protein, conserved 0.0028 0.0086 0.0125
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0028 0.0086 0.0387
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Plasmodium vivax tubulin alpha chain, putative 0.0669 0.5134 0.7418
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.01 0.0653 0.089
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0008 0.0011
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0028 0.0086 0.0118
Echinococcus granulosus epidermal growth factor receptor 0.0355 0.2657 0.3618
Echinococcus multilocularis tubulin delta chain 0.0231 0.1685 0.2295
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0187 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.1685 0.243
Echinococcus granulosus tubulin alpha 1C chain 0.0669 0.5134 0.6992
Brugia malayi prostaglandin transporter 0.0061 0.0346 0.0346
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0046 0.0226 0.0308
Echinococcus multilocularis beta tubulin 0.0896 0.6921 0.9425
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0551 0.0551
Entamoeba histolytica tubulin family protein 0.0896 0.6921 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.073 0.1054
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Brugia malayi Tubulin beta chain 0.0231 0.1685 0.1685
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Brugia malayi nuclear receptor NHR-88 0.0087 0.0551 0.0551
Onchocerca volvulus 0.0028 0.0086 0.0387
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0226 0.0226
Echinococcus multilocularis thyroid hormone receptor alpha 0.0226 0.1642 0.2236
Entamoeba histolytica tubulin gamma chain 0.0536 0.4083 0.5894
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0438 0.3311 0.3311
Loa Loa (eye worm) TK/INSR protein kinase 0.0131 0.0898 0.0898
Trichomonas vaginalis TK family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0028 0.0086 0.0086
Mycobacterium leprae Probable lipase LipE 0.004 0.0175 0.0293
Giardia lamblia Tenascin-like 0.0027 0.0079 0.0107
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0005 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0253 0.0253
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0253 0.0365
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0086 0.0118
Schistosoma mansoni agrin 0.0042 0.0193 0.0279
Echinococcus granulosus tubulin beta 1 chain 0.0896 0.6921 0.9425
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Leishmania major beta tubulin 0.0896 0.6921 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni tubulin subunit alpha 0.0669 0.5134 0.7418
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1857 0.4883
Loa Loa (eye worm) tubulin beta chain 0.0231 0.1685 0.1685
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0137 0.0941 0.1281
Schistosoma mansoni hypothetical protein 0.0114 0.076 0.1098
Echinococcus multilocularis fibrillin 1 0.0027 0.0079 0.0108
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi hypothetical protein 0.0061 0.0343 0.0343
Brugia malayi Tubulin alpha-2 chain 0.0669 0.5134 0.5134
Echinococcus granulosus adam 0.0027 0.0079 0.0108
Entamoeba histolytica receptor protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0033 0.012 0.0163
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Trichomonas vaginalis tubulin alpha chain, putative 0.0506 0.3848 0.5558
Loa Loa (eye worm) hypothetical protein 0.0438 0.3311 0.3311
Toxoplasma gondii ABC1 family protein 0.004 0.0175 0.0253
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0008 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0069 0.018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0253 0.0344
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0173 0.0243
Brugia malayi Protein kinase domain containing protein 0.0061 0.0343 0.0343
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0898 0.0898
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0099
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0137 0.0941 0.1281
Schistosoma mansoni tubulin subunit alpha 0.0231 0.1685 0.2435
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.0193 0.0279
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0134 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni tyrosine kinase 0.01 0.0653 0.0944
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0061 0.0343 0.0467
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0005 0.0007
Schistosoma mansoni tyrosine kinase 0.0035 0.0138 0.02
Echinococcus multilocularis transfer RNA-Thr 0.0028 0.0086 0.0118
Schistosoma mansoni growth factor receptor-bound protein 0.004 0.0177 0.0256
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0082 0.0118
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.0504 0.0717
Echinococcus granulosus dnaJ subfamily B 0.045 0.3408 0.4641
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0504 0.0686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0099
Toxoplasma gondii beta-tubulin, putative 0.0896 0.6921 1
Echinococcus granulosus Tubulin beta 2C chain 0.0896 0.6921 0.9425
Schistosoma mansoni integrin alpha-ps 0.0145 0.1006 0.1453
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0027 0.0079 0.0107
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0005 0.0007
Schistosoma mansoni tubulin subunit alpha 0.0669 0.5134 0.7418
Onchocerca volvulus 0.0028 0.0086 0.0387
Echinococcus granulosus tubulin alpha chain 0.0669 0.5134 0.6992
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0131
Brugia malayi hypothetical protein 0.0018 0.0004 0.0004
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0175 0.0461
Echinococcus multilocularis activated cdc42 kinase 1 0.0028 0.0086 0.0118
Brugia malayi Sex muscle abnormal protein 5 0.004 0.0177 0.0177
Schistosoma mansoni suppressor of cytokine signaling 0.0033 0.012 0.0173
Leishmania major cathepsin L-like protease 0.007 0.0416 0.0601
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Echinococcus granulosus tyrosine protein kinase Lyn 0.01 0.0653 0.089
Plasmodium falciparum thioredoxin reductase 0.0018 0.0005 0.0007
Echinococcus multilocularis Niemann Pick C1 protein 0.0108 0.0716 0.0976
Echinococcus granulosus kinase suppressor of Ras 1 0.0028 0.0086 0.0118
Loa Loa (eye worm) hypothetical protein 0.0046 0.0229 0.0229
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0112 0.0112
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0175 0.0448
Loa Loa (eye worm) tubulin alpha 2 0.0438 0.3311 0.3311
Brugia malayi integrin-linked kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0028 0.0086 0.0118
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0504 0.0728
Echinococcus multilocularis SHC transforming protein 3 0.0033 0.012 0.0163
Echinococcus granulosus tubulin alpha chain 0.0669 0.5134 0.6992
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Echinococcus granulosus activin receptor type 0.0028 0.0086 0.0118
Echinococcus multilocularis N chimaerin 0.0033 0.012 0.0163
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0551 0.0551
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0005 0.0007
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0061 0.0346 0.0472
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0041 0.0187 0.0271
Echinococcus multilocularis integrin alpha ps 0.0145 0.1006 0.137
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0144 0.0207
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Schistosoma mansoni steroid hormone receptor ad4bp 0.0087 0.0551 0.0796
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0253 0.0365
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0028 0.0086 0.0117
Leishmania major beta tubulin 0.0896 0.6921 1
Leishmania major gamma-tubulin 0.0536 0.4083 0.5899
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0551 0.075
Schistosoma mansoni alpha tubulin 0.0669 0.5134 0.7418
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1642 0.2372
Treponema pallidum ATP-dependent RNA helicase 0.0027 0.0075 0.0184
Plasmodium falciparum protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus granulosus tyrosine protein kinase Src42A 0.01 0.0653 0.089
Echinococcus multilocularis insulin receptor 0.0131 0.0898 0.1223
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0075 0.0101
Schistosoma mansoni integrin alpha-ps 0.0076 0.0458 0.0662
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0028 0.0086 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0175 0.0461
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Trypanosoma brucei Flagellum attachment zone protein 20 0.0028 0.0086 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0186 0.1332 0.1924
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni tensin 0.0033 0.012 0.0173
Echinococcus multilocularis lamin 0.003 0.0097 0.0132
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0027 0.0075 0.0197
Onchocerca volvulus Putative organic anion transporter 0.0061 0.0346 0.1676
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Loa Loa (eye worm) hypothetical protein 0.0076 0.0458 0.0458
Echinococcus multilocularis c src tyrosine kinase 0.0068 0.0401 0.0545
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0086 0.0118
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0187 0.0255
Echinococcus granulosus agrin 0.0042 0.0193 0.0263
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0075 0.0101
Echinococcus granulosus integrin alpha ps 0.007 0.0411 0.0559
Schistosoma mansoni single-minded 0.0054 0.0285 0.0411
Onchocerca volvulus 0.0061 0.0346 0.1676
Echinococcus multilocularis Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0435 0.0435
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Giardia lamblia Delta tubulin 0.0231 0.1685 0.243
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0298 0.043
Schistosoma mansoni tubulin subunit beta 0.0231 0.1685 0.2435
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0008 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0033 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0045 0.0216 0.0312
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.0551 0.0796
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0086 0.0118
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0027 0.0075 0.0331
Entamoeba histolytica cysteine surface protein, putative 0.0028 0.0086 0.0113
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0187 0.0271
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0187 0.0255
Loa Loa (eye worm) TK/ACK protein kinase 0.0028 0.0086 0.0086
Brugia malayi nuclear receptor RXR 0.0041 0.0187 0.0187
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0108 0.0716 0.1024
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0097 0.0097
Echinococcus granulosus survival motor neuron protein 1 0.026 0.1913 0.2605
Toxoplasma gondii beta-1 tubulin, putative 0.0896 0.6921 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis expressed conserved protein 0.0102 0.0665 0.0905
Echinococcus multilocularis Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.05 0.3803 0.5495
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0028 0.0086 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Entamoeba histolytica hypothetical protein 0.004 0.0175 0.0241
Onchocerca volvulus Putative organic anion transporter 0.0061 0.0346 0.1676
Leishmania major delta tubulin, putative 0.0415 0.3132 0.4525
Echinococcus granulosus raf serine:threonine protein kinase 0.0028 0.0086 0.0118
Brugia malayi Variant SH3 domain containing protein 0.004 0.0177 0.0177
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0028 0.0086 0.0118
Leishmania major cathepsin L-like protease 0.0018 0.0008 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0966 0.0966
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0504 0.0686
Echinococcus multilocularis Tubulin beta 2C chain 0.0896 0.6921 0.9425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0008 0.0022
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Echinococcus granulosus NCK adaptor protein 0.004 0.0177 0.0241
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus granulosus Immunoglobulin 0.0023 0.0045 0.0061
Leishmania major cathepsin L-like protease 0.0018 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0245 0.1791 0.1791
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0134 0.0923 0.1256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Echinococcus multilocularis kinase suppressor of Ras 1 0.0028 0.0086 0.0118
Schistosoma mansoni tyrosine kinase 0.0131 0.0898 0.1297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0098
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Echinococcus multilocularis Tubulin beta 2C chain 0.0896 0.6921 0.9425
Trypanosoma brucei alpha tubulin, putative 0.0275 0.2026 0.2928
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0033 0.012 0.0173
Echinococcus granulosus Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Brugia malayi hypothetical protein 0.0198 0.1421 0.1421
Brugia malayi hypothetical protein 0.0046 0.0226 0.0226
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0087 0.0551 0.0796
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Brugia malayi nuclear receptor NHR-67 0.0041 0.0187 0.0187
Plasmodium falciparum tyrosine kinase-like protein 0.0028 0.0086 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0026 0.0071 0.0096
Loa Loa (eye worm) protein kinase domain-containing protein 0.0028 0.0086 0.0086
Echinococcus granulosus neuropeptide s receptor 0.0518 0.3946 0.5374
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0028 0.0086 0.0125
Loa Loa (eye worm) hypothetical protein 0.0115 0.077 0.077
Onchocerca volvulus 0.0033 0.012 0.0554
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus tumor protein p63 0.0372 0.2792 0.3802
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0111 0.0161
Giardia lamblia Kinase, NEK 0.0028 0.0086 0.0117
Plasmodium falciparum tubulin epsilon chain, putative 0.0535 0.4079 0.5894
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0194 0.0265
Echinococcus multilocularis cpg binding protein 0.0033 0.0126 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Plasmodium falciparum alpha tubulin 1 0.0669 0.5134 0.7418
Trypanosoma brucei zeta tubulin, putative 0.0538 0.4103 0.5929
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0097
Schistosoma mansoni follistatin 0.0042 0.0193 0.0279
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0254 0.1864 0.1864
Toxoplasma gondii alpha-tubulin I, putative 0.0669 0.5134 0.7418
Schistosoma mansoni cell adhesion molecule 0.003 0.0096 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Echinococcus granulosus c src tyrosine kinase 0.0068 0.0401 0.0545
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Onchocerca volvulus 0.0033 0.012 0.0554
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0292 0.0422
Echinococcus multilocularis geminin 0.0186 0.1332 0.1814
Echinococcus granulosus peroxisome assembly protein 26 0.0669 0.5134 0.6992
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0075 0.0101
Trypanosoma brucei beta tubulin 0.0896 0.6921 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0005 0.0007
Schistosoma mansoni protein tyrosine kinase 0.0028 0.0086 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0173 0.0243
Brugia malayi hypothetical protein 0.026 0.1913 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0551 0.075
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus expressed conserved protein 0.0102 0.0665 0.0905
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0087 0.0551 0.0796
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0435 0.0618
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0229 0.0324
Toxoplasma gondii STE kinase 0.0028 0.0086 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0187 0.0271
Leishmania major cathepsin L-like protease 0.007 0.0416 0.0601
Brugia malayi beta-lactamase family protein 0.004 0.0175 0.0175
Mycobacterium ulcerans hypothetical protein 0.004 0.0175 0.0448
Loa Loa (eye worm) agrin synaptic family protein 0.0042 0.0193 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0028 0.0086 0.0086
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0033 0.012 0.012
Schistosoma mansoni intermediate filament proteins 0.003 0.0097 0.014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0008 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0131
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0086 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0087 0.0551 0.075
Schistosoma mansoni tyrosine kinase 0.0061 0.0343 0.0496
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.0798 0.2098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0253 0.0358
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0416 0.0601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Trypanosoma cruzi zeta tubulin, putative 0.0538 0.4103 0.5929
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Echinococcus multilocularis peroxisome assembly protein 26 0.0669 0.5134 0.6992
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0033 0.012 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0008
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.05 0.3803 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Brugia malayi Protein kinase domain containing protein 0.0061 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0057 0.0312 0.0312
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0153 0.0221
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0033 0.012 0.0173
Entamoeba histolytica tubulin alpha chain, putative 0.0669 0.5134 0.7415
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0068 0.0401 0.0545
Trypanosoma brucei epsilon tubulin 0.0535 0.4079 0.5894
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.01 0.0653 0.089
Schistosoma mansoni cpg binding protein 0.0033 0.0126 0.0182
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis tyrosine kinase 0.0061 0.0343 0.0467
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0079
Echinococcus granulosus tubulin alpha 0.0506 0.3848 0.5241
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0066 0.0095
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.0193 0.0279
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0273 0.0394
Brugia malayi Tubulin alpha chain 0.0669 0.5134 0.5134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0111 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0175 0.0246
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0187 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0093 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0173 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0173 0.0243
Treponema pallidum cell division protein FtsZ 0.0231 0.1685 0.4425
Schistosoma mansoni survival motor neuron protein 0.0053 0.0281 0.0406
Echinococcus multilocularis tubulin epsilon chain 0.0535 0.4079 0.5555
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0902 0.2373
Brugia malayi intermediate filament protein 0.003 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0061 0.0343 0.0467
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0028 0.0086 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Echinococcus granulosus roundabout 2 0.0033 0.0121 0.0165
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0111 0.0161
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0005 0.0007
Schistosoma mansoni tyrosine kinase 0.0203 0.1461 0.2111
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi sulfakinin receptor protein 0.0246 0.1799 0.1799
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0175 0.0253
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0065 0.0373 0.0508
Plasmodium vivax glutathione reductase, putative 0.0052 0.0273 0.0394
Loa Loa (eye worm) hypothetical protein 0.0091 0.0584 0.0584
Schistosoma mansoni zinc finger protein 0.0041 0.0187 0.0271
Onchocerca volvulus 0.004 0.0175 0.0827
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Onchocerca volvulus Bile acid receptor homolog 0.0087 0.0551 0.2688
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.0504 0.0686
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0093 0.0135
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Echinococcus granulosus SHC transforming protein 3 0.0033 0.012 0.0163
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Onchocerca volvulus 0.003 0.0097 0.0439
Loa Loa (eye worm) hypothetical protein 0.0042 0.0193 0.0193
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0086 0.0118
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0175 0.0175
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.036 0.0947
Echinococcus granulosus neuroglian 0.0026 0.007 0.0096
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0008 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0069 0.0167
Leishmania major beta tubulin 0.0896 0.6921 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0087 0.0551 0.0796
Trypanosoma cruzi epsilon tubulin, putative 0.0535 0.4079 0.5894
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0226 0.0226
Onchocerca volvulus Putative organic anion transporter 0.0061 0.0346 0.1676
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0086 0.0086
Brugia malayi Tyrosine-protein kinase PR2 0.0028 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0288 0.2131 0.2902
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma brucei Pseudokinase, putative 0.0028 0.0086 0.0125
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0273 0.0372
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Echinococcus multilocularis tyrosine protein kinase Src42A 0.01 0.0653 0.089
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0273 0.0372
Echinococcus multilocularis musashi 0.003 0.0097 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0087 0.0551 0.0551
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0069 0.0099
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.016
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0028 0.0086 0.0086
Leishmania major beta tubulin 0.0896 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Echinococcus multilocularis NCK adaptor protein 0.004 0.0177 0.0241
Trichomonas vaginalis tubulin gamma chain, putative 0.0536 0.4083 0.5896
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis integrin linked protein kinase 0.0028 0.0086 0.0118
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0086 0.0113
Leishmania major epsilon tubulin, putative 0.0535 0.4079 0.5894
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Giardia lamblia Tenascin-X 0.0027 0.0079 0.0107
Plasmodium vivax tubulin epsilon chain, putative 0.0535 0.4079 0.5894
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0506 0.3848 0.5561
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0028 0.0086 0.0118
Onchocerca volvulus 0.0061 0.0346 0.1676
Brugia malayi nuclear receptor RXR 0.0046 0.0226 0.0226
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0111 0.0161
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0229 0.0312
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0175 0.0461
Echinococcus granulosus lamin 0.003 0.0097 0.0132
Echinococcus multilocularis Tubulin beta 2C chain 0.0896 0.6921 0.9425
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0068 0.0401 0.0579
Trichomonas vaginalis tubulin gamma chain, putative 0.0231 0.1685 0.243
Trypanosoma brucei tubulin gamma chain 0.0536 0.4083 0.5899
Onchocerca volvulus 0.0061 0.0343 0.166
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0028 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0131 0.0898 0.0898
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0253 0.0344
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0028 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0551 0.0551
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0005 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0173 0.025
Loa Loa (eye worm) TK protein kinase 0.006 0.0339 0.0339
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0076 0.0109
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0111 0.0111
Toxoplasma gondii protease inhibitor PI2 0.0042 0.0193 0.0279
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Echinococcus granulosus tubulin subunit TubB 0.0669 0.5134 0.6992
Leishmania major protein kinase, putative 0.0028 0.0086 0.0125
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0046 0.0226 0.0327
Trichomonas vaginalis tubulin, putative 0.0896 0.6921 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0226 0.0327
Schistosoma mansoni patched 1 0.0046 0.0229 0.0331
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0008 0.0022
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0033 0.012 0.0163
Giardia lamblia Alpha-tubulin 0.0669 0.5134 0.7416
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0046 0.0226 0.0308
Schistosoma mansoni nuclear hormone receptor 0.0087 0.0551 0.0796
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0416 0.0601
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Onchocerca volvulus 0.0028 0.0086 0.0387
Onchocerca volvulus 0.004 0.0175 0.0827
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Onchocerca volvulus Protein ultraspiracle homolog 0.0087 0.0551 0.2688
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0435 0.0629
Trypanosoma cruzi MFS transporter, putative 0.0061 0.0346 0.05
Echinococcus multilocularis tensin 0.0033 0.012 0.0163
Brugia malayi SH2 domain containing protein 0.0061 0.0343 0.0343
Echinococcus granulosus tyrosine protein kinase HCK 0.006 0.0339 0.0462
Brugia malayi Cell division protein ftsZ 0.0231 0.1685 0.1685
Brugia malayi nuclear hormone receptor family member nhr-6 0.0041 0.0187 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Onchocerca volvulus 0.0028 0.0086 0.0387
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0245 0.1791 0.1791
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Entamoeba histolytica protein kinase, putative 0.0033 0.012 0.0162
Entamoeba histolytica ankyrin repeat protein 0.0028 0.0086 0.0113
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0082 0.0118
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0175 0.0253
Echinococcus multilocularis integrin alpha ps 0.0145 0.1006 0.137
Echinococcus multilocularis tubulin alpha 1C chain 0.0669 0.5134 0.6992
Loa Loa (eye worm) hypothetical protein 0.0081 0.0504 0.0504
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0435 0.0435
Brugia malayi orphan nuclear receptor NR2E1 0.0041 0.0187 0.0187
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0028 0.0086 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0087 0.0551 0.0551
Brugia malayi Tyrosine-protein kinase abl-1 0.014 0.0967 0.0967
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Trypanosoma brucei beta tubulin 0.0506 0.3848 0.5561
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.022 0.022
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0028 0.0086 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Brugia malayi Steroid receptor seven-up type 2 0.0087 0.0551 0.0551
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0041 0.0187 0.0255
Toxoplasma gondii tubulin, putative 0.0029 0.0094 0.0136
Echinococcus granulosus epidermal growth factor receptor 0.0203 0.1461 0.1989
Echinococcus multilocularis protein patched 0.0046 0.0229 0.0312
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0087 0.0551 0.0796
Schistosoma mansoni tyrosine kinase 0.0137 0.0941 0.1359
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0098
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0111 0.0151
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.0193 0.0193
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0584 0.0584
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0008 0.0004
Giardia lamblia Tenascin-37 0.0027 0.0079 0.0107
Schistosoma mansoni vav2 0.0033 0.012 0.0173
Mycobacterium leprae cell division protein FtsZ 0.0231 0.1685 0.4335
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0187 0.0888
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Loa Loa (eye worm) hypothetical protein 0.0042 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0173 0.025
Echinococcus granulosus integrin linked protein kinase 0.0028 0.0086 0.0118
Echinococcus granulosus protein tyrosine kinase 0.0028 0.0086 0.0118
Giardia lamblia High cysteine protein 0.0027 0.0079 0.0107
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0079
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.05 0.3803 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0061 0.0343 0.0467
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0069 0.0008
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0028 0.0086 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Onchocerca volvulus 0.0061 0.0343 0.166
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.05 0.3803 0.5495
Echinococcus granulosus suppressor of cytokine signaling 6 0.0033 0.012 0.0163
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0075 0.0108
Plasmodium vivax tubulin alpha chain, putative 0.0669 0.5134 0.7418
Leishmania major beta tubulin 0.0896 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Echinococcus granulosus twitchin 0.0026 0.007 0.0096
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Trichomonas vaginalis tubulin alpha chain, putative 0.0275 0.2026 0.2922
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0196 0.1405 0.1914
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.036 0.0935
Echinococcus granulosus bloom syndrome protein 0.0045 0.022 0.0299
Onchocerca volvulus 0.0061 0.0343 0.166
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Leishmania major hypothetical protein, conserved 0.004 0.0175 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0175 0.0253
Onchocerca volvulus 0.0033 0.012 0.0554
Plasmodium falciparum tyrosine kinase-like protein 0.0028 0.0086 0.0125
Echinococcus granulosus geminin 0.0186 0.1332 0.1814
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0134 0.0923 0.1256
Trichomonas vaginalis tubulin, putative 0.0261 0.192 0.2769
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0111 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni integrin beta subunit 0.0752 0.5785 0.8359
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0175 0.0175
Plasmodium falciparum glutathione reductase 0.0052 0.0273 0.0394
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0032 0.0112 0.0153
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0082 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0075 0.0108
Mycobacterium ulcerans beta-lactamase 0.004 0.0175 0.0448
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Schistosoma mansoni nuclear receptor 0.0041 0.0187 0.0271
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0086 0.0118
Plasmodium falciparum tubulin delta chain, putative 0.0231 0.1685 0.2435
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0175 0.0238
Entamoeba histolytica receptor protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0028 0.0086 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Echinococcus granulosus tensin 0.0033 0.012 0.0163
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0005 0.0007
Echinococcus multilocularis tubulin subunit TubB 0.0669 0.5134 0.6992
Loa Loa (eye worm) TK/EPH protein kinase 0.0028 0.0086 0.0086
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0033 0.012 0.0162
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Echinococcus granulosus Tubulin beta 2C chain 0.0896 0.6921 0.9425
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Mycobacterium leprae conserved hypothetical protein 0.004 0.0175 0.0293
Plasmodium vivax protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus granulosus SH2 domain containing adapter protein F 0.0033 0.012 0.0163
Schistosoma mansoni tyrosine kinase 0.0255 0.1874 0.2708
Echinococcus multilocularis bloom syndrome protein 0.0045 0.022 0.0299
Loa Loa (eye worm) glutathione reductase 0.0052 0.0273 0.0273
Loa Loa (eye worm) integrin alpha pat-2 0.0499 0.3792 0.3792
Loa Loa (eye worm) hypothetical protein 0.0246 0.1799 0.1799
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0066 0.016
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Echinococcus granulosus tubulin alpha chain 0.0669 0.5134 0.6992
Mycobacterium tuberculosis Cell division protein FtsZ 0.0231 0.1685 0.4432
Trypanosoma brucei trypanothione reductase 0.0052 0.0273 0.0394
Brugia malayi protein-tyrosine kinase 0.0093 0.0596 0.0596
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0086 0.0086
Giardia lamblia Neurogenic locus Notch protein precursor 0.0027 0.0079 0.0107
Giardia lamblia Beta tubulin 0.0896 0.6921 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0253 0.0358
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0028 0.0086 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis protein kinase 0.0028 0.0086 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0046 0.0226 0.0226
Leishmania major protein kinase, putative 0.0028 0.0086 0.0125
Schistosoma mansoni tyrosine protein kinase 0.0028 0.0086 0.0125
Giardia lamblia Beta tubulin 0.0896 0.6921 1
Giardia lamblia Protein 21.1 0.0028 0.0086 0.0117
Onchocerca volvulus 0.004 0.0175 0.0827
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0097
Brugia malayi Protein kinase domain containing protein 0.0061 0.0343 0.0343
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis epidermal growth factor receptor 0.0203 0.1461 0.1989
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0504 0.0728
Brugia malayi EGF-like domain containing protein 0.0027 0.0079 0.0079
Mycobacterium ulcerans cell division protein FtsZ 0.0231 0.1685 0.4425
Echinococcus granulosus single minded 2 0.004 0.0175 0.0238
Schistosoma mansoni tyrosine kinase 0.0355 0.2657 0.3839
Brugia malayi SPARC precursor 0.0042 0.0193 0.0193
Brugia malayi Fibronectin type III domain containing protein 0.0026 0.0069 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) TK protein kinase 0.0093 0.0596 0.0596
Leishmania major hypothetical protein, conserved 0.0028 0.0082 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0028 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0203 0.1461 0.2111
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0082 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus tyrosine protein kinase shark 0.0061 0.0343 0.0467
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi hypothetical protein 0.0041 0.0187 0.0187
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0435 0.0593
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0066 0.0095
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0087 0.0551 0.075
Trichomonas vaginalis tubulin alpha chain, putative 0.0275 0.2026 0.2922
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0902 0.2238
Echinococcus granulosus tyrosine protein kinase Blk 0.0093 0.0596 0.0812
Echinococcus multilocularis Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Echinococcus granulosus defective proboscis extension response 0.0023 0.0045 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0087 0.0551 0.0551
Plasmodium falciparum glutathione reductase 0.0018 0.0005 0.0007
Schistosoma mansoni tensin-related 0.0033 0.012 0.0173
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0086 0.0113
Trypanosoma cruzi epsilon tubulin, putative 0.0535 0.4079 0.5894
Echinococcus multilocularis raf serine:threonine protein kinase 0.0028 0.0086 0.0118
Brugia malayi nuclear hormone receptor 0.0087 0.0551 0.0551
Echinococcus multilocularis SH2 motif 0.0033 0.012 0.0163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0075
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0061 0.0343 0.0485
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0138 0.0954 0.1299
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0093 0.0596 0.0812
Echinococcus granulosus alpha tubulin 0.0669 0.5134 0.6992
Trypanosoma brucei protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus granulosus tubulin epsilon chain 0.0535 0.4079 0.5555
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0028 0.0086 0.0125
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis FTZ F1 alpha 0.0087 0.0551 0.075
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0075 0.0108
Echinococcus multilocularis tubulin alpha chain 0.0669 0.5134 0.6992
Brugia malayi nuclear hormone receptor 0.0041 0.0187 0.0187
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.0193 0.0279
Echinococcus multilocularis tubulin alpha 1C chain 0.0669 0.5134 0.6992
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0069 0.0167
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Toxoplasma gondii beta tubulin 0.0896 0.6921 1
Echinococcus granulosus SH2 motif 0.0033 0.012 0.0163
Echinococcus multilocularis FL cytokine receptor 0.0028 0.0086 0.0118
Trypanosoma cruzi protein kinase, putative 0.0028 0.0086 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0023 0.0045 0.0064
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0005 0.0007
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0005 0.0007
Echinococcus granulosus tyrosine protein kinase ABL1 0.0288 0.2131 0.2902
Echinococcus granulosus suppressor of cytokine signaling 7 0.0033 0.012 0.0163
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0008 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Echinococcus granulosus SH2 domain containing protein 7 0.0033 0.012 0.0163
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.05 0.3803 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0086 0.0118
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0028 0.0086 0.0086
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0027 0.0075 0.0101
Brugia malayi tubulin alpha-2 chain 0.0669 0.5134 0.5134
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0025 0.0036
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.0193 0.0193
Echinococcus multilocularis protein KINase family member (kin 25) 0.0028 0.0086 0.0118
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Echinococcus multilocularis tyrosine protein kinase Src64B 0.01 0.0653 0.089
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0653 0.089
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.0798 0.2098
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.01 0.0653 0.089
Loa Loa (eye worm) hypothetical protein 0.0054 0.0292 0.0292
Giardia lamblia High cysteine protein 0.0027 0.0079 0.0107
Mycobacterium tuberculosis Conserved protein 0.004 0.0175 0.0461
Schistosoma mansoni hypothetical protein 0.0033 0.012 0.0173
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0229 0.0229
Onchocerca volvulus 0.0061 0.0346 0.1676
Schistosoma mansoni hypothetical protein 0.0028 0.0086 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni coup transcription factor 0.0087 0.0551 0.0796
Echinococcus multilocularis hypothetical protein 0.0669 0.5134 0.6992
Echinococcus granulosus Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0187 0.0187
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0138 0.0954 0.1299
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0071
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0134 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0069 0.0167
Loa Loa (eye worm) sex muscle abnormal protein 5 0.004 0.0177 0.0177
Plasmodium falciparum protein kinase, putative 0.0028 0.0086 0.0125
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0075 0.0108
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0335 0.0484
Mycobacterium tuberculosis Probable reductase 0.0119 0.0798 0.2098
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0504 0.0728
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0253 0.0365
Onchocerca volvulus 0.0091 0.0584 0.2852
Mycobacterium ulcerans hypothetical protein 0.0026 0.0069 0.0167
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.01 0.0653 0.089
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0041 0.0187 0.0187
Loa Loa (eye worm) integrin beta-2 0.1287 1 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0111 0.0151
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0082 0.0118
Schistosoma mansoni GTPase activating protein 0.0033 0.012 0.0173
Brugia malayi hypothetical protein 0.018 0.1278 0.1278
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0415 0.3132 0.4525
Echinococcus granulosus intermediate filament protein 0.003 0.0097 0.0132
Loa Loa (eye worm) serine/threonine protein kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0033 0.012 0.0163
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0061 0.0346 0.0346
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0008 0.0011
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0097 0.0097
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.0504 0.0728
Echinococcus multilocularis cysteine protease 0.0018 0.0008 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni alpha tubulin 0.0669 0.5134 0.7418
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0504 0.0722
Brugia malayi EGF-like domain containing protein 0.0027 0.0079 0.0079
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Trichomonas vaginalis tubulin gamma chain, putative 0.0535 0.4079 0.5891
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0231 0.1685 0.4425
Brugia malayi Integrin alpha pat-2 precursor 0.0323 0.2412 0.2412
Echinococcus multilocularis fibrillin 2 0.0027 0.0079 0.0108
Brugia malayi Protein kinase domain containing protein 0.0061 0.0343 0.0343
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi CXXC zinc finger family protein 0.0032 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Entamoeba histolytica tubulin alpha-1 chain 0.0669 0.5134 0.7415
Brugia malayi CHE-14 protein 0.0046 0.0229 0.0229
Plasmodium vivax tyrosine kinase-like protein, putative 0.0028 0.0086 0.0125
Plasmodium falciparum protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0435 0.0593
Echinococcus multilocularis protein kinase 0.0028 0.0086 0.0118
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0281 0.0281
Brugia malayi Tubulin beta-1 chain 0.0896 0.6921 0.6921
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Toxoplasma gondii hypothetical protein 0.0027 0.0079 0.0114
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0175 0.0461
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0008 0.0012
Echinococcus multilocularis integrin alpha 3 0.0248 0.1817 0.2474
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.036 0.0521
Echinococcus multilocularis tyrosine kinase 0.0028 0.0086 0.0118
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0028 0.0086 0.0118
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0033 0.012 0.0163
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0008 0.0011
Schistosoma mansoni tubulin subunit alpha 0.0669 0.5134 0.7418
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0033 0.012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0099
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.0798 0.2098
Brugia malayi tRNA modification GTPase TrmE family protein 0.0033 0.012 0.012
Schistosoma mansoni integrin alpha 0.0323 0.2412 0.3485
Mycobacterium tuberculosis Conserved protein 0.004 0.0175 0.0461
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Loa Loa (eye worm) BEN-1 protein 0.0896 0.6921 0.6921
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.05 0.3803 1
Trichomonas vaginalis tubulin beta chain, putative 0.0275 0.2026 0.2922
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0008 0.0011
Plasmodium falciparum eukaryotic initiation factor 4A 0.0027 0.0075 0.0108
Brugia malayi ephrin receptor 1 precursor 0.0028 0.0086 0.0086
Echinococcus multilocularis Tubulin beta 2C chain 0.0896 0.6921 0.9425
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus tubulin beta 4A class IVa 0.0896 0.6921 0.9425
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0005 0.0007
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Trypanosoma cruzi zeta tubulin, putative 0.0538 0.4103 0.5929
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0892 0.6891 0.9385
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.012 0.012
Toxoplasma gondii thioredoxin reductase 0.0052 0.0273 0.0394
Leishmania major beta tubulin 0.0896 0.6921 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0173 0.025
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0005 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Onchocerca volvulus 0.0033 0.012 0.0554
Loa Loa (eye worm) TK protein kinase 0.014 0.0966 0.0966
Toxoplasma gondii cathepsin CPL 0.0018 0.0008 0.0012
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0669 0.5134 0.7416
Echinococcus granulosus beta tubulin 0.0896 0.6921 0.9425
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.05 0.3803 1
Echinococcus multilocularis tubulin gamma 1 chain 0.0536 0.4083 0.556
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0504 0.0686
Onchocerca volvulus 0.0033 0.012 0.0554
Entamoeba histolytica protein kinase, putative 0.006 0.0339 0.0479
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0504 0.0504
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Brugia malayi EGF-like domain containing protein 0.0027 0.0079 0.0079
Brugia malayi glutathione reductase 0.0052 0.0273 0.0273
Echinococcus granulosus integrin beta 2 0.0949 0.7343 1
Echinococcus granulosus fibrillin 2 0.0027 0.0079 0.0108
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0005 0.0007
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0261 0.1916 0.2769
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0028 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Brugia malayi STAT protein, DNA binding domain containing protein 0.0033 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0027 0.0075 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.007 0.0411 0.0594
Loa Loa (eye worm) tubulin alpha-3 chain 0.0394 0.2971 0.2971
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus multilocularis lamin dm0 0.003 0.0097 0.0132
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) nuclear hormone receptor 0.0041 0.0187 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0116 0.016
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0551 0.0551
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0033 0.012 0.012
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0028 0.0086 0.0113
Brugia malayi tailless protein 0.0041 0.0187 0.0187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0087 0.0551 0.0551
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Giardia lamblia Epsilon tubulin 0.0261 0.1916 0.2764
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi hypothetical protein 0.004 0.0175 0.0175
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0047 0.0068
Schistosoma mansoni tensin-related 0.0033 0.012 0.0173
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0504 0.0728
Onchocerca volvulus 0.0061 0.0343 0.166
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.1083 0.1474
Echinococcus granulosus follistatin 0.0042 0.0193 0.0263
Plasmodium vivax RNA helicase-1, putative 0.0027 0.0075 0.0108
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.012 0.012
Echinococcus granulosus tubulin alpha 3 chain 0.0669 0.5134 0.6992
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0124 0.0172
Plasmodium vivax tyrosine kinase-like protein, putative 0.0028 0.0086 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0008 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0175 0.0246
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis protein tyrosine kinase 0.0028 0.0086 0.0118
Loa Loa (eye worm) TK/CSK protein kinase 0.0028 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0086 0.0118
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0175 0.0238
Leishmania major cathepsin L-like protease 0.007 0.0416 0.0601
Echinococcus multilocularis integrin alpha ps 0.007 0.0411 0.0559
Mycobacterium ulcerans lipase LipD 0.004 0.0175 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.1685 0.243
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis SH2 domain containing protein 7 0.0033 0.012 0.0163
Loa Loa (eye worm) hypothetical protein 0.0042 0.0193 0.0193
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0042 0.0193 0.0193
Echinococcus granulosus eukaryotic initiation factor 4A 0.0027 0.0075 0.0102
Schistosoma mansoni DNA helicase recq1 0.0031 0.0111 0.0161
Brugia malayi sodium-independent organic anion transporter family protein 0.0061 0.0346 0.0346
Schistosoma mansoni tensin 0.0033 0.012 0.0173
Loa Loa (eye worm) hypothetical protein 0.007 0.0411 0.0411
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.036 0.0491
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0253 0.0365
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0187 0.0255
Brugia malayi Tubulin alpha chain 0.0231 0.1685 0.1685
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0086 0.0125
Echinococcus granulosus tyrosine protein kinase Src64B 0.01 0.0653 0.089
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0008 0.0012
Onchocerca volvulus 0.0026 0.0069 0.0299
Loa Loa (eye worm) SRC-1 0.01 0.0653 0.0653
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase HCK 0.006 0.0339 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0087 0.0551 0.0551
Leishmania major cathepsin L-like protease 0.0018 0.0008 0.0012
Brugia malayi hypothetical protein 0.0061 0.0346 0.0346
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Loa Loa (eye worm) TK/FAK protein kinase 0.0028 0.0086 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0069 0.018
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0134 0.0193
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Schistosoma mansoni tensin 0.0033 0.012 0.0173
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Loa Loa (eye worm) tubulin beta-4 chain 0.0896 0.6921 0.6921
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0082 0.0118
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0653 0.089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0055 0.0294 0.0294
Echinococcus granulosus ecdysone induced protein 78C 0.0087 0.0551 0.075
Plasmodium falciparum tubulin beta chain 0.0896 0.6921 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.0097 0.0097
Schistosoma mansoni vesicular amine transporter 0.0023 0.0045 0.0064
Loa Loa (eye worm) TK/Met protein kinase 0.0028 0.0086 0.0086
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0028 0.0086 0.0125
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.004 0.0177 0.0256
Trypanosoma brucei beta tubulin 0.0896 0.6921 1
Schistosoma mansoni tyrosine kinase 0.0061 0.0343 0.0496
Echinococcus multilocularis natriuretic peptide receptor 1 0.0028 0.0086 0.0118
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.0193 0.0193
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Brugia malayi Immunoglobulin I-set domain containing protein 0.0055 0.0294 0.0294
Loa Loa (eye worm) TK/ALK protein kinase 0.0028 0.0086 0.0086
Trichomonas vaginalis tubulin epsilon chain, putative 0.0896 0.6921 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0071 0.0102
Trichomonas vaginalis hypothetical protein 0.0027 0.0079 0.0107
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.0798 0.2098
Echinococcus granulosus tubulin alpha chain 0.0669 0.5134 0.6992
Loa Loa (eye worm) hypothetical protein 0.004 0.0177 0.0177
Brugia malayi photoreceptor-specific nuclear receptor 0.0087 0.0551 0.0551
Giardia lamblia GTOR 0.0049 0.0253 0.0358
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.0504 0.0686
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0194 0.0265
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0069 0.0167
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Brugia malayi hypothetical protein 0.0046 0.0226 0.0226
Loa Loa (eye worm) BEN-1 protein 0.0896 0.6921 0.6921
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Echinococcus granulosus hypothetical protein 0.0033 0.012 0.0163
Echinococcus granulosus tubulin delta chain 0.0231 0.1685 0.2295
Leishmania major beta tubulin 0.0896 0.6921 1
Brugia malayi tubulin alpha chain - mouse 0.0669 0.5134 0.5134
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Trichomonas vaginalis tubulin beta chain, putative 0.0896 0.6921 1
Leishmania major cathepsin L-like protease 0.0018 0.0008 0.0012
Schistosoma mansoni shc transforming protein 0.0033 0.012 0.0173
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0087 0.0551 0.0796
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0416 0.0601
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0902 0.2373
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0008 0.0012
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0898 0.0898
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Leishmania major beta tubulin 0.0896 0.6921 1
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.05 0.3803 0.5495
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0041 0.0187 0.0255
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0069 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0086 0.0117
Brugia malayi RhoGAP domain containing protein 0.0033 0.012 0.012
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0005 0.0007
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0253 0.0365
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis tyrosine protein kinase Srms 0.0093 0.0596 0.0812
Loa Loa (eye worm) variant SH3 domain-containing protein 0.004 0.0177 0.0177
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0175 0.0448
Giardia lamblia Kinase, NEK 0.0028 0.0086 0.0117
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0086 0.0086
Brugia malayi secreted modular calcium-binding protein 1 0.0042 0.0193 0.0193
Brugia malayi hypothetical protein 0.0028 0.0086 0.0086
Entamoeba histolytica hypothetical protein 0.004 0.0175 0.0241
Echinococcus multilocularis Tubulin beta 2C chain 0.0896 0.6921 0.9425
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Trypanosoma cruzi beta tubulin, putative 0.0896 0.6921 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0087 0.0551 0.075
Schistosoma mansoni ephrin receptor 0.0028 0.0086 0.0125
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni organic anion transporter 0.0061 0.0346 0.05
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0285 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Entamoeba histolytica tubulin family protein 0.0896 0.6921 1
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis heat shock protein 70 0.0028 0.0086 0.0118
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Echinococcus granulosus tyrosine protein kinase Srms 0.0061 0.0343 0.0467
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0033 0.012 0.0163
Schistosoma mansoni ephrin receptor 0.0031 0.0111 0.0161
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0075 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0087 0.0551 0.0551
Echinococcus multilocularis neuroglian 0.0026 0.007 0.0096
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Entamoeba histolytica hypothetical protein 0.0028 0.0086 0.0113
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) tubulin alpha-2 chain 0.0669 0.5134 0.5134
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.0193 0.0193
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0023 0.0045 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0069 0.0008
Echinococcus multilocularis neuropeptide s receptor 0.0518 0.3946 0.5374
Toxoplasma gondii protein kinase 0.0028 0.0086 0.0125
Echinococcus multilocularis ephrin type A receptor 4 A 0.0028 0.0086 0.0118
Brugia malayi Kelch motif family protein 0.0198 0.1421 0.1421
Echinococcus granulosus protein kinase 0.0028 0.0086 0.0118
Schistosoma mansoni serine/threonine RGC 0.0028 0.0086 0.0125
Trypanosoma brucei alpha tubulin 0.0669 0.5134 0.7418
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Leishmania major beta tubulin 0.0896 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Trypanosoma brucei alpha tubulin 0.0669 0.5134 0.7418
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0086 0.0118
Loa Loa (eye worm) tubulin alpha chain 0.0669 0.5134 0.5134
Trypanosoma cruzi tubulin gamma chain 0.0536 0.4083 0.5899
Trypanosoma brucei alpha tubulin 0.0669 0.5134 0.7418
Echinococcus granulosus Tubulin beta 2C chain 0.0896 0.6921 0.9425
Brugia malayi nuclear hormone receptor family member odr-7 0.0041 0.0187 0.0187
Brugia malayi C-terminal src kinase protein 1 0.0028 0.0086 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus tubulin alpha 3 chain 0.0669 0.5134 0.6992
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0066 0.0095
Loa Loa (eye worm) tubulin alpha 2 0.0163 0.1148 0.1148
Echinococcus multilocularis 0.0033 0.012 0.0163
Leishmania major trypanothione reductase 0.0052 0.0273 0.0394
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0093
Echinococcus multilocularis tumor protein p63 0.0372 0.2792 0.3802
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0033 0.012 0.0173
Echinococcus granulosus tyrosine kinase 0.0028 0.0086 0.0118
Giardia lamblia hypothetical protein 0.0027 0.0079 0.0107
Echinococcus multilocularis tubulin alpha chain 0.0669 0.5134 0.6992
Echinococcus granulosus cathepsin l1 0.0018 0.0008 0.0011
Brugia malayi sodium-independent organic anion transporter family protein 0.0061 0.0346 0.0346
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) tubulin gamma chain 0.0536 0.4083 0.4083
Schistosoma mansoni lamin 0.003 0.0097 0.014
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0203 0.1461 0.1989
Schistosoma mansoni cpg binding protein 0.0033 0.0126 0.0182
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0008 0.0008
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0061 0.0343 0.0343
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0086 0.0125
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni alpha tubulin 0.0669 0.5134 0.7418
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.1168 0.1168
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.022 0.031
Schistosoma mansoni nuclear receptor nhr-48 0.0041 0.0187 0.0271
Onchocerca volvulus 0.0041 0.0187 0.0888
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0066 0.016
Plasmodium falciparum alpha tubulin 2 0.0669 0.5134 0.7418
Schistosoma mansoni RAR-like nuclear receptor 0.0087 0.0551 0.0796
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0086 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0069 0.0069
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0229 0.0312
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0394 0.2971 0.2971
Echinococcus granulosus tyrosine kinase 0.0093 0.0596 0.0812
Brugia malayi nuclear receptor NHR-88 0.0041 0.0187 0.0187
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0273 0.0273
Trichomonas vaginalis esterase, putative 0.004 0.0175 0.0246
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0086 0.0125
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni cpg binding protein 0.0032 0.0112 0.0162
Mycobacterium tuberculosis Conserved protein 0.004 0.0175 0.0461
Brugia malayi Thioredoxin reductase 0.0052 0.0273 0.0273
Brugia malayi hypothetical protein 0.0028 0.0082 0.0082
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0134 0.0193
Leishmania major beta tubulin 0.0896 0.6921 1
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0086 0.0086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Echinococcus multilocularis roundabout 2 0.0033 0.0121 0.0165
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0005 0.0007
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0086 0.0387
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0005 0.0007
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.036 0.036
Plasmodium vivax vivapain-2 0.0018 0.0008 0.0012
Loa Loa (eye worm) tubulin beta chain 0.0896 0.6921 0.6921
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0027 0.0075 0.0097
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Brugia malayi hypothetical protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) alpha-tubulin 0.0669 0.5134 0.5134
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0069 0.0167
Trichomonas vaginalis tubulin gamma chain, putative 0.0896 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0098
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0134 0.0181
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0069 0.0069
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni tyrosine kinase 0.0068 0.0401 0.0579
Trypanosoma brucei zeta tubulin 0.0538 0.4103 0.5929
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0069 0.0087
Schistosoma mansoni growth factor receptor-bound protein 0.004 0.0177 0.0256
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0584 0.0795
Schistosoma mansoni hypothetical protein 0.0033 0.012 0.0173
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.01 0.0653 0.089
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0175 0.0246
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni tyrosine kinase 0.0174 0.1237 0.1788
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus tyrosine protein kinase 0.0028 0.0086 0.0118
Echinococcus multilocularis expressed protein 0.0042 0.0193 0.0263
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Blk 0.0093 0.0596 0.0812
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus natriuretic peptide receptor 1 0.0028 0.0086 0.0118
Echinococcus granulosus Tubulin alpha 1 chain 0.0669 0.5134 0.6992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Echinococcus granulosus Tubulin beta 2C chain 0.0896 0.6921 0.9425
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Echinococcus multilocularis dnaJ subfamily B 0.045 0.3408 0.4641
Echinococcus multilocularis tubulin alpha chain 0.0669 0.5134 0.6992
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0005 0.0007
Echinococcus multilocularis epidermal growth factor receptor 0.0355 0.2657 0.3618
Onchocerca volvulus 0.0275 0.2026 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0075 0.0108
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.0504 0.0722
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Onchocerca volvulus 0.0028 0.0086 0.0387
Loa Loa (eye worm) hypothetical protein 0.026 0.1913 0.1913
Giardia lamblia Alpha-tubulin 0.0669 0.5134 0.7416
Schistosoma mansoni nuclear receptor 0.0041 0.0187 0.0271
Toxoplasma gondii alpha tubulin TUBA1 0.0669 0.5134 0.7418
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Schistosoma mansoni hypothetical protein 0.0053 0.0281 0.0406
Schistosoma mansoni tyrosine kinase 0.0174 0.1237 0.1788
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0066 0.0173
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.0504 0.0728
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0435 0.0629
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0033 0.012 0.0163
Trichomonas vaginalis tubulin epsilon chain, putative 0.0669 0.5134 0.7416
Brugia malayi SH2 domain containing protein 0.0033 0.012 0.012
Echinococcus multilocularis Immunoglobulin 0.0023 0.0045 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0087 0.0551 0.075
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0175 0.0246
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0253 0.0354
Loa Loa (eye worm) hypothetical protein 0.0042 0.0193 0.0193
Echinococcus granulosus tubulin subunit beta 0.0896 0.6921 0.9425
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus fibroblast growth factor receptor 4 0.0137 0.0941 0.1281
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0027 0.0075 0.0102
Brugia malayi hypothetical protein 0.0041 0.0187 0.0187
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0551 0.075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi Furin-like cysteine rich region family protein 0.0355 0.2657 0.2657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0093 0.0128
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0027 0.0075 0.0108
Brugia malayi Tubulin gamma chain 0.0536 0.4083 0.4083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0153 0.0214
Onchocerca volvulus 0.0028 0.0086 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.0111
Plasmodium falciparum tubulin gamma chain 0.0536 0.4083 0.5899
Schistosoma mansoni nck2/grb4 0.004 0.0177 0.0256
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.0798 0.1959
Brugia malayi Cathepsin L-like precursor 0.0018 0.0008 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0087 0.0551 0.075
Schistosoma mansoni DNA helicase recq5 0.0031 0.0111 0.0161
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.05 0.3803 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0355 0.2657 0.2657
Trichomonas vaginalis tubulin, putative 0.0275 0.2026 0.2922
Schistosoma mansoni hypothetical protein 0.0138 0.0954 0.1379
Brugia malayi ecdysone receptor 0.0041 0.0187 0.0187
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0027 0.0075 0.0108
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Echinococcus multilocularis beta tubulin 0.0896 0.6921 0.9425
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0087 0.0551 0.075
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0653 0.089
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Brugia malayi bone morphogenetic protein type 1 receptor 0.0028 0.0086 0.0086
Schistosoma mansoni lamin 0.003 0.0097 0.014
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) TK/RYK protein kinase 0.0028 0.0086 0.0086
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0017 0.003
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis nuclear receptor nhr 48 0.0041 0.0187 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0073 0.0099
Trypanosoma cruzi alpha tubulin, putative 0.0669 0.5134 0.7418
Plasmodium vivax tubulin gamma chain, putative 0.0536 0.4083 0.5899
Trypanosoma brucei epsilon tubulin 0.0506 0.3848 0.5561
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0551 0.075
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0435 0.0629
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0368 0.0532
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0066 0.0095
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0175 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0087 0.0551 0.0551
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0069 0.0087
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0435 0.0629
Echinococcus multilocularis 0.0102 0.0663 0.0903
Echinococcus granulosus tyrosine protein kinase pr2 0.0028 0.0086 0.0118
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0033 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Trichomonas vaginalis protein tyrosine kinase, putative 0.0028 0.0086 0.0117
Echinococcus multilocularis tyrosine protein kinase Abl 0.0155 0.1084 0.1476
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0253 0.0354
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.012 0.012
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0033 0.012 0.012
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Plasmodium vivax hypothetical protein, conserved 0.004 0.0175 0.0253
Echinococcus granulosus ephrin type A receptor 4 A 0.0028 0.0086 0.0118
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0231 0.1685 0.243
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0435 0.0629
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0112 0.0112
Loa Loa (eye worm) fibroinase 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Onchocerca volvulus 0.0061 0.0343 0.166
Schistosoma mansoni hypothetical protein 0.0045 0.0216 0.0312
Trypanosoma brucei beta tubulin 0.0896 0.6921 1
Echinococcus multilocularis SH2 motif 0.0033 0.012 0.0163
Echinococcus multilocularis Immunoglobulin 0.0023 0.0045 0.0061
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.036 0.0521
Echinococcus granulosus activated cdc42 kinase 1 0.0028 0.0086 0.0118
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.1083 0.1474
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0394 0.2971 0.4289
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.036 0.0935
Echinococcus granulosus tyrosine protein kinase Src42A 0.0065 0.0373 0.0508
Echinococcus multilocularis growth factor receptor bound protein 2 0.004 0.0177 0.0241
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) nuclear receptor NHR-67 0.0041 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0186 0.1332 0.1924
Brugia malayi Variant SH3 domain containing protein 0.004 0.0177 0.0177
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0504 0.0722
Brugia malayi Tubulin alpha-2 chain 0.0669 0.5134 0.5134
Schistosoma mansoni hypothetical protein 0.0045 0.0216 0.0312
Onchocerca volvulus 0.0061 0.0343 0.166
Brugia malayi Variant SH3 domain containing protein 0.0033 0.012 0.012
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Echinococcus granulosus thyroid hormone receptor alpha 0.0041 0.0187 0.0255
Echinococcus granulosus Niemann Pick C1 protein 0.0108 0.0716 0.0976
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0086 0.0117
Giardia lamblia Beta tubulin 0.0896 0.6921 1
Schistosoma mansoni tubulin subunit epsilon 0.0535 0.4079 0.5894
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0023 0.0045 0.0061
Loa Loa (eye worm) RecQ helicase 0.0045 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0582 0.4445 0.6053
Echinococcus granulosus growth factor receptor bound protein 2 0.004 0.0177 0.0241
Loa Loa (eye worm) tubulin beta-2A chain 0.0896 0.6921 0.6921
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0504 0.0722
Echinococcus granulosus Solute carrier organic anion transporter family 0.0061 0.0346 0.0472
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0033 0.012 0.0163
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Loa Loa (eye worm) tubulin alpha 2 0.0438 0.3311 0.3311
Echinococcus granulosus insulin receptor 0.0131 0.0898 0.1223
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Brugia malayi hypoxia-induced factor 1 0.0166 0.1168 0.1168
Onchocerca volvulus 0.0061 0.0346 0.1676
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0584 0.0843
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0551 0.0551
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0033 0.012 0.0163
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0068 0.0401 0.0545
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0066 0.016
Brugia malayi beta-lactamase 0.004 0.0175 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0087 0.0551 0.075
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0028 0.0086 0.0125
Echinococcus multilocularis tubulin alpha 0.0506 0.3848 0.5241
Echinococcus multilocularis integrin beta 2 0.0949 0.7343 1
Plasmodium vivax tubulin beta chain, putative 0.0896 0.6921 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0896 0.6921 1
Onchocerca volvulus 0.0033 0.012 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Entamoeba histolytica hypothetical protein 0.004 0.0175 0.0241
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Schistosoma mansoni tubulin subunit delta 0.0231 0.1685 0.2435
Echinococcus granulosus Tubulin beta 2C chain 0.0896 0.6921 0.9425
Trypanosoma cruzi tubulin delta chain 0.0415 0.3132 0.4525
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0086 0.0086
Onchocerca volvulus 0.0028 0.0086 0.0387
Loa Loa (eye worm) hypothetical protein 0.0198 0.1421 0.1421
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0028 0.0086 0.0086
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0111 0.0151
Loa Loa (eye worm) tubulin beta-1 chain 0.0896 0.6921 0.6921
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0028 0.0086 0.0118
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus granulosus activated cdc42 kinase 1 0.0028 0.0086 0.0118
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0017 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0087 0.0551 0.0551
Onchocerca volvulus 0.0042 0.0193 0.0916
Onchocerca volvulus 0.0061 0.0346 0.1676
Trichomonas vaginalis protein kinase atn1, putative 0.0028 0.0086 0.0117
Onchocerca volvulus Tyrosine kinase homolog 0.0032 0.0112 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0028 0.0086 0.0086
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0082 0.0118
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0584 0.0795
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Echinococcus multilocularis ecdysone induced protein 78C 0.0087 0.0551 0.075
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0653 0.089
Trypanosoma cruzi protein kinase, putative 0.0028 0.0086 0.0125
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0028 0.0086 0.0117
Loa Loa (eye worm) TK protein kinase 0.0028 0.0086 0.0086
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus tyrosine kinase 0.0061 0.0343 0.0467
Echinococcus granulosus cpg binding protein 0.0033 0.0126 0.0172
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Schistosoma mansoni tyrosine kinase 0.0131 0.0898 0.1297
Brugia malayi SRC-1 0.01 0.0653 0.0653
Trypanosoma brucei tubulin delta chain 0.0415 0.3132 0.4525
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0175 0.0253
Brugia malayi MH2 domain containing protein 0.0131 0.0898 0.0898
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0061 0.0346 0.0472
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0175 0.0461
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0391 0.0565
Trichomonas vaginalis STE family protein kinase 0.0028 0.0086 0.0117
Giardia lamblia Kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) TK/DDR protein kinase 0.0028 0.0086 0.0086
Echinococcus multilocularis tubulin alpha chain 0.0669 0.5134 0.6992
Onchocerca volvulus 0.0053 0.0281 0.1352
Echinococcus multilocularis tyrosine protein kinase 0.0028 0.0086 0.0118
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0028 0.0086 0.0125
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0086 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi EGF-like domain containing protein 0.0027 0.0079 0.0079
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0033 0.012 0.0163
Brugia malayi sodium-independent organic anion transporter family protein 0.0061 0.0346 0.0346
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0028 0.0086 0.0125
Entamoeba histolytica SH2 domain containing protein 0.0033 0.012 0.0162
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0008 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0087 0.0551 0.0551
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0175 0.0246
Trichomonas vaginalis tubulin epsilon chain, putative 0.0669 0.5134 0.7416
Schistosoma mansoni organic anion transporter 0.0061 0.0346 0.05
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0416 0.0601
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0028 0.0086 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0086 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0253 0.0358
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0069 0.0099
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0902 0.2373
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0086 0.0118
Echinococcus multilocularis tyrosine protein kinase pr2 0.0028 0.0086 0.0118
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0086 0.0086
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0273 0.0718
Echinococcus multilocularis activin receptor type 0.0028 0.0086 0.0118
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0653 0.089
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Giardia lamblia Gamma tubulin 0.0536 0.4083 0.5896
Echinococcus multilocularis tubulin alpha 3 chain 0.0669 0.5134 0.6992
Brugia malayi conserved hypotetical protein 0.0041 0.0187 0.0187
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0504 0.0686
Echinococcus multilocularis tubulin alpha chain 0.0669 0.5134 0.6992
Loa Loa (eye worm) hypothetical protein 0.0041 0.0187 0.0187
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0069 0.0167
Trichomonas vaginalis tubulin alpha chain, putative 0.0275 0.2026 0.2922
Onchocerca volvulus 0.0027 0.0079 0.0351
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0111 0.0151
Onchocerca volvulus 0.0028 0.0086 0.0387
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.022 0.031
Echinococcus granulosus signal transduction protein lnk realted 0.0033 0.012 0.0163
Schistosoma mansoni nephrin 0.0029 0.0095 0.0138
Trichomonas vaginalis tubulin beta chain, putative 0.0669 0.5134 0.7416
Brugia malayi eukaryotic initiation factor 4A 0.0027 0.0075 0.0075
Echinococcus multilocularis cysteine protease 0.0018 0.0008 0.0011
Toxoplasma gondii transporter, major facilitator family protein 0.0061 0.0346 0.05
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Echinococcus granulosus FTZ F1 alpha 0.0087 0.0551 0.075
Loa Loa (eye worm) beta-tubulin 0.0896 0.6921 0.6921
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0087 0.0551 0.0551
Brugia malayi Tensin 0.0033 0.012 0.012
Leishmania major beta tubulin 0.0896 0.6921 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0187 0.0255
Plasmodium vivax vivapain-2 0.0018 0.0008 0.0012
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0028 0.0086 0.0086
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0197 0.0285
Entamoeba histolytica ankyrin repeat protein 0.0028 0.0086 0.0113
Entamoeba histolytica hypothetical protein 0.004 0.0175 0.0241
Brugia malayi Tubulin beta chain 0.0275 0.2026 0.2026
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0253 0.0365
Loa Loa (eye worm) steroid hormone receptor 0.0087 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Loa Loa (eye worm) cysteine protease 0.0018 0.0008 0.0008
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0033 0.012 0.012
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0093 0.0596 0.0812
Brugia malayi hypothetical protein 0.0246 0.1799 0.1799
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0041 0.0187 0.0187
Trichomonas vaginalis tubulin alpha chain, putative 0.0896 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.018 0.1278 0.1278
Loa Loa (eye worm) tubulin alpha chain 0.0669 0.5134 0.5134
Schistosoma mansoni tyrosine kinase 0.0068 0.0401 0.0579
Schistosoma mansoni suppressor of cytokine signaling 0.0033 0.012 0.0173
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0069 0.0087
Schistosoma mansoni adapter molecule crk 0.004 0.0177 0.0256
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0087 0.0551 0.075
Loa Loa (eye worm) hypothetical protein 0.0669 0.5134 0.5134
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0028 0.0086 0.0118
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0027 0.0075 0.0102
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0069 0.0167
Loa Loa (eye worm) hypothetical protein 0.0033 0.012 0.012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.0798 0.2098
Echinococcus multilocularis tubulin subunit beta 0.0896 0.6921 0.9425
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Brugia malayi hypothetical protein 0.0033 0.012 0.012
Schistosoma mansoni SH2A 0.0033 0.012 0.0173
Onchocerca volvulus 0.0054 0.0292 0.1405
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Brugia malayi alpha-tubulin 0.0669 0.5134 0.5134
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0061 0.0346 0.0472
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma cruzi tubulin delta chain 0.0415 0.3132 0.4525
Echinococcus granulosus tubulin alpha chain 0.0669 0.5134 0.6992
Echinococcus multilocularis signal transduction protein lnk realted 0.0033 0.012 0.0163
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0187 0.0888
Echinococcus multilocularis SH2 motif 0.0033 0.012 0.0163
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0087 0.0551 0.2688
Echinococcus granulosus nuclear receptor nhr 48 0.0041 0.0187 0.0255
Echinococcus granulosus tubulin alpha 1C chain 0.0669 0.5134 0.6992
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Leishmania major cathepsin L-like protease 0.0018 0.0008 0.0012
Schistosoma mansoni tubulin subunit beta 0.0896 0.6921 1
Echinococcus multilocularis tubulin beta 1 chain 0.0896 0.6921 0.9425
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0086 0.0118
Brugia malayi Tyrosine-protein kinase abl-1 0.0155 0.1084 0.1084
Loa Loa (eye worm) hypothetical protein 0.0087 0.0551 0.0551
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0066 0.0095
Trichomonas vaginalis tubulin, putative 0.0275 0.2026 0.2922
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0086 0.0118
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0008 0.0012
Loa Loa (eye worm) STAT protein 0.0033 0.012 0.012
Trypanosoma brucei alpha tubulin 0.0669 0.5134 0.7418
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1642 0.2372
Echinococcus multilocularis tyrosine protein kinase Fgr 0.01 0.0653 0.089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Echinococcus granulosus SH2 motif 0.0033 0.012 0.0163
Echinococcus granulosus expressed conserved protein 0.0033 0.012 0.0163
Brugia malayi Niemann-Pick C1 protein precursor 0.0108 0.0716 0.0716
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0229 0.0312
Loa Loa (eye worm) beta-lactamase 0.004 0.0175 0.0175
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0033 0.012 0.0163
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0175 0.0238
Loa Loa (eye worm) hypothetical protein 0.004 0.0175 0.0175
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0028 0.0086 0.0113
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Onchocerca volvulus 0.0028 0.0086 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0087 0.0551 0.0551
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0008 0.0004
Onchocerca volvulus 0.0087 0.0551 0.2688
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0087 0.0551 0.0551
Loa Loa (eye worm) TK/ABL protein kinase 0.0288 0.2131 0.2131
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0041 0.0187 0.0271
Echinococcus multilocularis neuropeptide receptor A26 0.0518 0.3946 0.5374
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.015 0.1042 0.1419
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0086 0.0118
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.1913 0.2605
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0086 0.0113
Toxoplasma gondii protein kinase domain-containing protein 0.0028 0.0086 0.0125
Onchocerca volvulus 0.0032 0.0112 0.0514
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Brugia malayi hypothetical protein 0.0061 0.0346 0.0346
Schistosoma mansoni tubulin subunit gamma 0.0536 0.4083 0.5899
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0137 0.0941 0.1281
Echinococcus granulosus integrin alpha 3 0.0248 0.1817 0.2474
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0086 0.0113
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0045 0.0216 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0087 0.0551 0.0551
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0273 0.0394
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0017 0.0024
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0061 0.0346 0.0346
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0198 0.1421 0.1421
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Echinococcus granulosus integrin alpha ps 0.0145 0.1006 0.137
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0551 0.0551
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi hypothetical protein 0.0026 0.0069 0.0069
Echinococcus multilocularis adam 0.0027 0.0079 0.0108
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Giardia lamblia Neurogenic locus notch-like protein 0.0027 0.0079 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0173 0.0243
Brugia malayi PAS domain containing protein 0.0054 0.0285 0.0285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0551 0.0551
Schistosoma mansoni tyrosine kinase 0.0174 0.1237 0.1788
Echinococcus multilocularis follistatin 0.0042 0.0193 0.0263
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0086
Echinococcus multilocularis protein dispatched 1 0.0053 0.0281 0.0383
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0253 0.0253
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0175 0.0253
Loa Loa (eye worm) DR-78 0.0041 0.0187 0.0187
Brugia malayi Protein kinase domain containing protein 0.0028 0.0086 0.0086
Brugia malayi beta-lactamase family protein 0.004 0.0175 0.0175
Schistosoma mansoni tyrosine kinase 0.0028 0.0086 0.0125
Brugia malayi beta-tubulin, identical 0.0896 0.6921 0.6921
Schistosoma mansoni protein kinase 0.0028 0.0086 0.0125
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0086 0.0113
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0033 0.012 0.0554
Loa Loa (eye worm) TK/FER protein kinase 0.0061 0.0343 0.0343
Leishmania major zeta tubulin, putative 0.0538 0.4103 0.5929
Trichomonas vaginalis tubulin epsilon chain, putative 0.0231 0.1685 0.243
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.036 0.0491
Entamoeba histolytica protein kinase, putative 0.0028 0.0086 0.0113
Brugia malayi ecdysteroid receptor 0.0087 0.0551 0.0551
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0033 0.012 0.0163
Brugia malayi bHLH-PAS transcription factor 0.004 0.0175 0.0175
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0253 0.0365
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Brugia malayi steroid hormone receptor 0.0087 0.0551 0.0551
Leishmania major alpha tubulin 0.0669 0.5134 0.7418
Echinococcus granulosus neuropeptide receptor A26 0.0518 0.3946 0.5374
Trichomonas vaginalis TKL family protein kinase 0.0028 0.0086 0.0117

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 67.7 uM Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPH ChEMBL. 23819803
Kd (binding) = 0.32 uM Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2 ChEMBL. 23819803

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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