Detailed information for compound 1780902

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 166.137 | Formula: C6H6N4O2
  • H donors: 2 H acceptors: 3 LogP: -0.08 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc2n(n1)c(=O)[nH]c(=O)[nH]2
  • InChi: 1S/C6H6N4O2/c1-3-2-4-7-5(11)8-6(12)10(4)9-3/h2H,1H3,(H2,7,8,11,12)
  • InChiKey: FPYPRXRHPYSDPF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.019 0.018
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0009 0.0062
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0013 0.0005 0.0003
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0041
Onchocerca volvulus 0.0035 0.0124 0.2092
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0052 0.0214 0.021
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0168 0.0831 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0124 0.0386
Schistosoma mansoni ferritin light chain 0.0017 0.0027 0.0027
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0043 0.0039
Brugia malayi MH2 domain containing protein 0.024 0.1217 0.8891
Schistosoma mansoni terminal deoxycytidyl transferase 0.0052 0.0214 0.0214
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0282 0.0282
Schistosoma mansoni cpg binding protein 0.0085 0.0391 0.0391
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0043 0.0043
Schistosoma mansoni endoplasmin 0.0032 0.0105 0.0105
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0076 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0115 0.0105
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0034 0.003
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0124 0.1396
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0021 0.0055
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0125 0.0116
Loa Loa (eye worm) oxidoreductase 0.0014 0.0009 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0043 0.0039
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.0348 0.1108
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0115 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Mycobacterium leprae Probable lipase LipE 0.0035 0.0124 0.1396
Brugia malayi Ceramide kinase 0.0073 0.0327 0.2363
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0327 0.1038
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Mycobacterium ulcerans hypothetical protein 0.1882 1 1
Echinococcus multilocularis ceramide kinase 0.0073 0.0327 0.0322
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0168 0.0831 0.6062
Schistosoma mansoni smad1 5 8 and 0.0016 0.0022 0.0022
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0021 0.0125
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0124 0.0124
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0133
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0027 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0043 0.0039
Plasmodium vivax endoplasmin, putative 0.0032 0.0105 0.1217
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0124 0.0386
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0043 0.0039
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0009 0.0005
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.019 0.018
Entamoeba histolytica hypothetical protein 0.0037 0.0132 0.0128
Toxoplasma gondii hypothetical protein 0.0096 0.0447 0.5349
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0246
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0021 0.0055
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0136 0.0131
Schistosoma mansoni ran 0.0021 0.0046 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Echinococcus multilocularis dna polymerase eta 0.0077 0.0348 0.0344
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Trypanosoma brucei DNA polymerase IV, putative 0.0072 0.0319 0.1015
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0234 0.0224
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0027 0.0018
Brugia malayi Importin beta-1 subunit 0.0028 0.0086 0.0597
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.1549 0.1545
Onchocerca volvulus 0.0014 0.0009 0.0089
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0021 0.0055
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1146 0.1138
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.029 0.0286
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0198 0.0995 0.0991
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0381 0.1213
Schistosoma mansoni zinc finger protein 0.0024 0.0064 0.0064
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0193 0.0189
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0354 0.1127
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0021 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Echinococcus granulosus cpg binding protein 0.0092 0.0427 0.0423
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0021 0.0055
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0124 0.0119
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0073 0.0327 0.1038
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0121
Trichomonas vaginalis endoplasmin, putative 0.002 0.0039 0.0255
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0234 0.0738
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0015
Brugia malayi ecdysteroid receptor 0.002 0.0043 0.0284
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0168 0.0831 1
Leishmania major DNA polymerase kappa, putative 0.0059 0.0249 0.0787
Schistosoma mansoni hypothetical protein 0.0174 0.0866 0.0866
Schistosoma mansoni phd/f-box containing protein 0.0016 0.002 0.002
Brugia malayi Smad1 0.0016 0.0022 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0043 0.0284
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0024 0.002
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0073 0.0327 0.2363
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.007 0.0212
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.002 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0043 0.0284
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.019 0.018
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0035
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.027 0.0266
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0011 0.0075
Onchocerca volvulus 0.0085 0.0391 0.6751
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0043 0.0039
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0043 0.0039
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0124 0.0115
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0047 0.0312
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0024 0.002
Trichomonas vaginalis sphingosine kinase, putative 0.0073 0.0327 0.2363
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0076 0.0071
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0021 0.0205
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0124 0.0879
Loa Loa (eye worm) hypothetical protein 0.0048 0.019 0.0185
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.4167 0.4165
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0073 0.0327 0.1038
Echinococcus granulosus endoplasmin 0.0025 0.007 0.0066
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0073 0.0327 0.2363
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0043 0.0284
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0479 0.1527
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0022 0.0018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.019 0.018
Echinococcus granulosus heat shock protein 0.0032 0.0105 0.0101
Schistosoma mansoni ferritin 0.0017 0.0027 0.0027
Echinococcus granulosus ceramide kinase 0.0073 0.0327 0.0322
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Entamoeba histolytica hypothetical protein 0.0037 0.0132 0.0128
Echinococcus multilocularis neuropeptide receptor A26 0.0453 0.236 0.2356
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0043 0.0676
Loa Loa (eye worm) hypothetical protein 0.0063 0.027 0.0266
Onchocerca volvulus 0.0014 0.0009 0.0089
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.007 0.0212
Echinococcus granulosus Smad4 0.0016 0.0022 0.0018
Schistosoma mansoni microtubule-associated protein tau 0.135 0.7155 0.7155
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0043 0.0039
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0009 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.019 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0052 0.0214 0.0214
Plasmodium falciparum diacylglycerol kinase, putative 0.0073 0.0327 0.3897
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Brugia malayi Bromodomain containing protein 0.0038 0.0136 0.0967
Brugia malayi diacylglycerol kinase 0.0073 0.0327 0.2363
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.002 0.0015
Entamoeba histolytica hypothetical protein 0.0037 0.0132 0.0128
Schistosoma mansoni bromodomain containing protein 0.0067 0.0294 0.0294
Brugia malayi MH1 domain containing protein 0.0016 0.0022 0.0129
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0124 0.0124
Brugia malayi Endoplasmin precursor 0.0032 0.0105 0.0738
Brugia malayi hypothetical protein 0.012 0.0577 0.4199
Brugia malayi polk-prov protein 0.0042 0.0161 0.1151
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0115 0.0105
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0043 0.0039
Leishmania major mitochondrial DNA polymerase beta 0.0594 0.3109 1
Schistosoma mansoni hypothetical protein 0.0063 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.003
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Leishmania major hypothetical protein, conserved 0.0016 0.002 0.0049
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0105 0.0324
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0078 0.0354 0.2565
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0282 0.0278
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0009 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0124 0.0879
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.002 0.002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0009 0.0005
Brugia malayi mbt repeat family protein 0.0048 0.0193 0.1387
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0303
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0043 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Trypanosoma cruzi Sphingosine kinase 0.0073 0.0327 0.1038
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0229 0.0225
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0105 0.0324
Echinococcus multilocularis Diacylglycerol kinase theta 0.0073 0.0327 0.0322
Toxoplasma gondii histone lysine methyltransferase SET1 0.0164 0.0812 0.9766
Loa Loa (eye worm) diacylglycerol kinase 2 0.0073 0.0327 0.0322
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.002 0.0049
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.0168 0.0831 0.0827
Echinococcus granulosus Diacylglycerol kinase theta 0.0073 0.0327 0.0322
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Loa Loa (eye worm) hypothetical protein 0.0055 0.0229 0.0225
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0381 0.1213
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0021 0.0206
Echinococcus granulosus FTZ F1 alpha 0.002 0.0043 0.0039
Brugia malayi diacylglycerol kinase 0.0073 0.0327 0.2363
Trypanosoma brucei phosphoglycerate kinase 0.0168 0.0831 0.2663
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0009 0.0016
Trichomonas vaginalis heat shock protein, putative 0.0025 0.007 0.0483
Schistosoma mansoni thyroid hormone receptor 0.002 0.0043 0.0043
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0073 0.0327 0.0322
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0229 0.0225
Schistosoma mansoni sphingoid long chain base kinase 0.1882 1 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0043 0.0043
Toxoplasma gondii exonuclease III APE 0.0056 0.0234 0.2773
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0073 0.0327 0.3897
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Loa Loa (eye worm) beta-lactamase 0.0035 0.0124 0.012
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.019 0.0185
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0181
Mycobacterium ulcerans beta-lactamase 0.0035 0.0124 0.0115
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.027 0.0266
Brugia malayi heat shock protein 90 0.0032 0.0105 0.0738
Leishmania major hypothetical protein, conserved 0.0073 0.0327 0.1038
Loa Loa (eye worm) hypothetical protein 0.0048 0.0193 0.0189
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0009 0.0037
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0193 0.0193
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0105 0.0324
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0193 0.0193
Trichomonas vaginalis heat shock protein, putative 0.0025 0.007 0.0483
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0112
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0009 0.0037
Schistosoma mansoni phosphoglycerate kinase 0.0168 0.0831 0.0831
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0234 0.0738
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.007 0.0212
Schistosoma mansoni glutaminase 0.0268 0.1368 0.1368
Trichomonas vaginalis sphingosine kinase, putative 0.0073 0.0327 0.2363
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0234 0.1681
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0009 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0043 0.0284
Schistosoma mansoni heat shock protein 0.0032 0.0105 0.0105
Giardia lamblia Phosphoglycerate kinase 0.0168 0.0831 1
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0035 0.0099
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0112
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0254 0.025
Brugia malayi beta-lactamase family protein 0.0035 0.0124 0.0879
Onchocerca volvulus 0.0035 0.0124 0.2092
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0009 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0132 0.0128
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0021 0.0055
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0009 0.0062
Mycobacterium tuberculosis Conserved protein 0.1882 1 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0043 0.0284
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0022 0.0018
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0105 0.1217
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0043 0.0284
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0234 0.0229
Schistosoma mansoni jumonji domain containing protein 0.006 0.0254 0.0254
Echinococcus multilocularis expressed protein 0.0017 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0198 0.0995 0.0991
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0137 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0327 0.2363
Loa Loa (eye worm) hypothetical protein 0.0077 0.0348 0.0344
Trypanosoma cruzi diacylglycerol kinase, putative 0.0073 0.0327 0.1038
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0021 0.0055
Plasmodium vivax phosphoglycerate kinase, putative 0.0168 0.0831 1
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0327 0.1038
Echinococcus granulosus bloom syndrome protein 0.0021 0.0047 0.0043
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.1015 0.1011
Schistosoma mansoni ap endonuclease 0.0056 0.0234 0.0234
Plasmodium vivax diacylglycerol kinase, putative 0.0073 0.0327 0.3897
Schistosoma mansoni hypothetical protein 0.0136 0.0659 0.0659
Schistosoma mansoni Smad4 0.0016 0.0022 0.0022
Onchocerca volvulus Huntingtin homolog 0.012 0.0577 1
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.0659 0.4804
Loa Loa (eye worm) hypothetical protein 0.0073 0.0327 0.0322
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.002 0.0015
Echinococcus granulosus GPCR family 2 0.0063 0.027 0.0266
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0234 0.2773
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0027 0.0215
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0073 0.0327 0.0327
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0501
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0043 0.0039
Loa Loa (eye worm) MBCTL1 0.0055 0.0229 0.0225
Plasmodium vivax diacylglycerol kinase, putative 0.0073 0.0327 0.3897
Brugia malayi hypothetical protein 0.0037 0.0132 0.0938
Echinococcus multilocularis zinc finger protein 0.0024 0.0064 0.0059
Echinococcus multilocularis neuropeptide s receptor 0.0453 0.236 0.2356
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Loa Loa (eye worm) hypothetical protein 0.0073 0.0327 0.0322
Brugia malayi beta-lactamase 0.0035 0.0124 0.0879
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0234 0.1681
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0021 0.0017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.002 0.0049
Echinococcus granulosus dna polymerase eta 0.0077 0.0348 0.0344
Schistosoma mansoni heat shock protein 0.0013 0.0004 0.0004
Leishmania major DNA polymerase eta, putative 0.0077 0.0348 0.1108
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0282 0.0278
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0043 0.0676
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0168 0.0831 0.2663
Schistosoma mansoni hypothetical protein 0.0037 0.0132 0.0132
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0057 0.0387
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0079 0.0075
Leishmania major phosphoglycerate kinase C, glycosomal 0.0168 0.0831 0.2663
Plasmodium vivax JmjC domain containing protein 0.0016 0.002 0.0185
Schistosoma mansoni hypothetical protein 0.0306 0.1569 0.1569
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0043 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0043 0.0039
Trichomonas vaginalis heat shock protein, putative 0.0025 0.007 0.0483
Schistosoma mansoni hypothetical protein 0.0174 0.0866 0.0866
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0043 0.0039
Entamoeba histolytica hypothetical protein 0.0023 0.0057 0.0053
Echinococcus multilocularis geminin 0.0174 0.0866 0.0862
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Toxoplasma gondii diacylglycerol kinase, putative 0.0073 0.0327 0.3897
Trypanosoma brucei Sphingosine kinase 0.0073 0.0327 0.1038
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0133
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1437 0.4614
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0015
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0021 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0234 0.0738
Trypanosoma brucei unspecified product 0.0072 0.0319 0.1015
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0105 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0043 0.0284
Leishmania major hypothetical protein, conserved 0.0073 0.0327 0.1038
Schistosoma mansoni hypothetical protein 0.0302 0.1549 0.1549
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0073 0.0327 0.3897
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0076 0.0071
Brugia malayi hypothetical protein 0.0073 0.0327 0.2363
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0124 0.0115
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.029 0.0286
Schistosoma mansoni diacylglycerol kinase theta 0.0073 0.0327 0.0327
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0234 0.2568
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0086 0.0262
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.019 0.2194
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0249 0.0787
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0043 0.0039
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.002 0.0015
Entamoeba histolytica phosphoglycerate kinase, putative 0.0168 0.0831 0.0827
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0028 0.0023
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.002 0.0185
Echinococcus multilocularis smad 0.0016 0.0022 0.0018
Echinococcus multilocularis Smad4 0.0016 0.0022 0.0018
Echinococcus multilocularis GPCR, family 2 0.0063 0.027 0.0266
Toxoplasma gondii ABC1 family protein 0.0035 0.0124 0.1449
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0009 0.0009
Trypanosoma brucei diacylglycerol kinase, putative 0.0073 0.0327 0.1038
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.007 0.074
Schistosoma mansoni protein phosphatase 2C 0.0016 0.002 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0168 0.0831 0.2663
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0009 0.0016
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0021 0.0055
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0048 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0048 0.019 0.1359
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0229 0.0225
Echinococcus multilocularis phosphoglycerate kinase 1 0.0168 0.0831 0.0827
Schistosoma mansoni cpg binding protein 0.0092 0.0427 0.0427
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0304
Leishmania major DNA polymerase kappa, putative 0.0016 0.0021 0.0055
Echinococcus granulosus microtubule associated protein 2 0.135 0.7155 0.7154
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0043 0.0284
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0105 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Loa Loa (eye worm) hypothetical protein 0.007 0.0307 0.0303
Trichomonas vaginalis glutaminase, putative 0.0268 0.1368 1
Mycobacterium ulcerans glutaminase 0.0268 0.1368 0.136
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0282 0.0895
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0009 0.0016
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0275 0.0271
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0043 0.0676
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0254 0.025
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0354 0.0345
Plasmodium falciparum phosphoglycerate kinase 0.0168 0.0831 1
Leishmania major DNA polymerase eta, putative 0.0041 0.0155 0.0487
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.019 0.018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0043 0.0043
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0017
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0073 0.0327 0.1038
Onchocerca volvulus Huntingtin homolog 0.012 0.0577 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.019 0.2194
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0015
Schistosoma mansoni diacylglycerol kinase theta 0.0073 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0024
Mycobacterium ulcerans hypothetical protein 0.0313 0.1607 0.1599
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0009 0.0016
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0105 0.1217
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0021 0.0055
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0327 0.0322
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.019 0.018
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0086 0.0262
Echinococcus multilocularis cpg binding protein 0.0092 0.0427 0.0423
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0121
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0043 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0162 0.0508
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0043 0.0284
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0124 0.0879
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.002 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0354 0.0345
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0043 0.0043
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0249 0.0787
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0043 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0048 0.0048
Mycobacterium ulcerans hypothetical protein 0.0048 0.019 0.018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0043 0.0039
Trichomonas vaginalis diacylglycerol kinase, putative 0.0073 0.0327 0.2363
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0021 0.0017
Echinococcus granulosus phd:f box containing protein 0.0016 0.002 0.0015
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0048 0.0044
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0105 0.0101
Onchocerca volvulus 0.002 0.0043 0.0676
Loa Loa (eye worm) RecQ helicase 0.0021 0.0047 0.0043
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Trichomonas vaginalis helicase, putative 0.0019 0.0038 0.0246
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0229 0.0225
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0105 0.1033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.027 0.0266
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0009 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Brugia malayi RNA, U transporter 1 0.008 0.0365 0.2641
Leishmania major phosphoglycerate kinase B, cytosolic 0.0168 0.0831 0.2663
Giardia lamblia DINP protein human, muc B family 0.0059 0.0249 0.281
Echinococcus multilocularis heat shock protein 90 0.0025 0.007 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0043 0.0284
Trypanosoma brucei phosphoglycerate kinase 0.0168 0.0831 0.2663
Echinococcus granulosus smad 0.0016 0.0022 0.0018
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0229 0.0229
Mycobacterium tuberculosis Conserved hypothetical protein 0.0052 0.0214 0.0205
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0048 0.019 0.0185
Mycobacterium tuberculosis Conserved protein 0.0035 0.0124 0.0115
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0124 0.0879
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0193 0.0193
Echinococcus multilocularis endoplasmin 0.0025 0.007 0.0066
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0594 0.3109 1
Schistosoma mansoni coup transcription factor 0.002 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0073 0.0327 0.0322
Schistosoma mansoni hypothetical protein 0.0063 0.027 0.027
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0021 0.0012
Trypanosoma brucei unspecified product 0.0036 0.0127 0.0396
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0073 0.0327 0.0322
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0081
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0057 0.017
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0354 0.1127
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.002 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0048 0.019 0.1359
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0027 0.0018
Schistosoma mansoni hypothetical protein 0.0073 0.0327 0.0327
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.007 0.0536
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.002 0.0185
Onchocerca volvulus 0.0073 0.0327 0.5627
Echinococcus multilocularis snurportin 1 0.0302 0.1549 0.1545
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0381 0.1213
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1217 0.1213
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0017
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0168 0.0831 1
Schistosoma mansoni apoferritin-2 0.0017 0.0027 0.0027
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.029 0.029
Echinococcus granulosus neuropeptide s receptor 0.0453 0.236 0.2356
Mycobacterium ulcerans diacylglycerol kinase 0.0073 0.0327 0.0317
Leishmania major hypothetical protein, conserved 0.0035 0.0124 0.0386
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0009 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0249 0.024
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.002 0.0049
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0105 0.0101
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0327 0.0322
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0157
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0009 0.0037
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.3109 1
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0062 0.0264 0.0835
Onchocerca volvulus 0.0048 0.019 0.3237
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.012 0.0577 0.0573
Schistosoma mansoni smad 0.0016 0.0022 0.0022
Echinococcus granulosus dna polymerase kappa 0.0078 0.0354 0.035
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.027 0.1948
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Leishmania major importin beta-1 subunit, putative 0.0023 0.0057 0.017
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0021 0.0205
Schistosoma mansoni DNA polymerase eta 0.0077 0.0348 0.0348
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1217 0.1213
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.027 0.0266
Echinococcus granulosus Diacylglycerol kinase zeta 0.0073 0.0327 0.0322
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0041
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0501
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.0155 0.1828
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0124 0.0115
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0009 0.0005
Loa Loa (eye worm) glutaminase 2 0.0268 0.1368 0.1364
Onchocerca volvulus 0.0035 0.0124 0.2092
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0021 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0391 0.0387
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0124 0.0115
Onchocerca volvulus 0.0048 0.0193 0.3302
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0056 0.0051
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Chlamydia trachomatis phosphoglycerate kinase 0.0168 0.0831 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0234 0.2773
Echinococcus granulosus ferritin 0.0017 0.0027 0.0023
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0254 0.025
Brugia malayi Phosphoglycerate kinase 0.0062 0.0264 0.1901
Schistosoma mansoni smad1 5 8 and 0.0016 0.0022 0.0022
Trichomonas vaginalis diacylglycerol kinase, putative 0.0073 0.0327 0.2363
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0282 0.0895
Brugia malayi Latrophilin receptor protein 2 0.0063 0.027 0.1948
Mycobacterium ulcerans lipase LipD 0.0035 0.0124 0.0115
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0501
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0168 0.0831 0.0822
Brugia malayi MH2 domain containing protein 0.0016 0.0022 0.0129
Brugia malayi Phosphoglycerate kinase 0.0168 0.0831 0.6062
Loa Loa (eye worm) hypothetical protein 0.0136 0.0659 0.0655
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0009 0.0016
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0009 0.0016
Brugia malayi steroid hormone receptor 0.002 0.0043 0.0284
Loa Loa (eye worm) hypothetical protein 0.1882 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.001 0.0064
Mycobacterium tuberculosis Conserved protein 0.0035 0.0124 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0043 0.0284
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0168 0.0831 0.6062
Leishmania major hypothetical protein, conserved 0.0015 0.0015 0.0035
Mycobacterium tuberculosis Conserved protein 0.0035 0.0124 0.0115
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0193 0.0189
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0327 0.0322
Entamoeba histolytica deoxycytidyl transferase, putative 0.0052 0.0214 0.021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.019 0.0185
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0009 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0043 0.0039
Loa Loa (eye worm) glutaminase 0.0268 0.1368 0.1364
Schistosoma mansoni ran 0.0021 0.0046 0.0046
Schistosoma mansoni ferritin light chain 0.0017 0.0027 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0198 0.0995 0.7264
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0105 0.0324
Trypanosoma brucei ISWI complex protein 0.0015 0.0015 0.0035
Schistosoma mansoni ferritin 0.0017 0.0027 0.0027
Echinococcus granulosus geminin 0.0174 0.0866 0.0862
Brugia malayi Diacylglycerol kinase protein 2 0.0073 0.0327 0.2363
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0015
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0022 0.0018
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0009 0.0062
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0043 0.0039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0056 0.0051
Schistosoma mansoni phosphoglycerate kinase 0.0168 0.0831 0.0831
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0136 0.0131
Brugia malayi CXXC zinc finger family protein 0.0085 0.0391 0.2835
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Plasmodium falciparum importin beta, putative 0.0028 0.0086 0.0984
Trypanosoma brucei phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0193 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.019 0.018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0124 0.0115
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Mycobacterium ulcerans heat shock protein 90 0.0025 0.007 0.0061
Entamoeba histolytica hypothetical protein 0.0037 0.0132 0.0128
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0282 0.0895
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0121
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0021 0.0205
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0021 0.0206
Schistosoma mansoni zinc finger protein 0.0015 0.0015 0.0015
Echinococcus multilocularis heat shock protein 90 0.0032 0.0105 0.0101
Echinococcus multilocularis dnaJ subfamily B 0.1215 0.6435 0.6433
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.007 0.0605
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0234 0.0229
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0043 0.0039
Echinococcus granulosus snurportin 1 0.0302 0.1549 0.1545
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0034 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0115 0.0105
Treponema pallidum heat shock protein 90 0.0025 0.007 0.0536
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0043 0.0039
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0234 0.0229
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0234 0.2568
Trypanosoma cruzi Sphingosine kinase 0.0073 0.0327 0.1038
Leishmania major DNA damage repair protein, putative 0.0016 0.0021 0.0055
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0275 0.0271
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0043 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0015
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0043 0.0043
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0132 0.0128
Onchocerca volvulus Ceramide kinase 1 homolog 0.0073 0.0327 0.5627
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.012
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.019 0.0597
Schistosoma mansoni jumonji domain containing protein 0.0016 0.002 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0015
Schistosoma mansoni nuclear hormone receptor 0.002 0.0043 0.0043
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0105 0.0324
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0282 0.0278
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.019 0.018
Plasmodium vivax importin-beta 2, putative 0.0028 0.0086 0.0984
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0043 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0124 0.1449
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.007 0.0061
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0022 0.0018
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0193 0.3302
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0124 0.0119
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0047 0.0312
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0125 0.1462
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0161 0.0506
Onchocerca volvulus 0.0014 0.0009 0.0089
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Echinococcus multilocularis microtubule associated protein 2 0.135 0.7155 0.7154
Leishmania major diacylglycerol kinase-like protein 0.0073 0.0327 0.1038
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0214 0.1538
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0009 0.0037
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0234 0.0229
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0181 0.0903 0.0903
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Echinococcus granulosus expressed protein 0.0017 0.0027 0.0023
Schistosoma mansoni smad1 5 8 and 0.0016 0.0022 0.0022
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.0348 0.1108
Plasmodium falciparum heat shock protein 90 0.0032 0.0105 0.1217
Echinococcus multilocularis phd:f box containing protein 0.0016 0.002 0.0015
Echinococcus granulosus dnaJ subfamily B 0.1215 0.6435 0.6433
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0168 0.0831 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0043 0.0039
Brugia malayi Eye-specific diacylglycerol kinase 0.0073 0.0327 0.2363
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0381 0.1213
Schistosoma mansoni hypothetical protein 0.002 0.0043 0.0043
Brugia malayi beta-lactamase family protein 0.0035 0.0124 0.0879
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0022 0.0018
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0084 0.0584
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0124 0.0879
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0162 0.0508
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0073 0.0327 0.0322
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0124 0.0115
Leishmania major sphingosine kinase A, B, putative 0.0073 0.0327 0.1038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0034 0.0034
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0021 0.0206
Loa Loa (eye worm) hypothetical protein 0.0048 0.019 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0043 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.019 0.0597
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0282 0.0278
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.0041
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0073 0.0327 0.0322
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0043 0.0039
Schistosoma mansoni heat shock protein 0.0032 0.0105 0.0105
Echinococcus multilocularis sphingosine kinase 1 0.1882 1 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0055
Echinococcus multilocularis dna polymerase kappa 0.0078 0.0354 0.035
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0086 0.0081
Schistosoma mansoni thyroid hormone receptor 0.002 0.0043 0.0043
Mycobacterium ulcerans hypothetical protein 0.0035 0.0124 0.0115
Trichomonas vaginalis esterase, putative 0.0035 0.0124 0.0879
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0234 0.0738
Schistosoma mansoni ferritin 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Schistosoma mansoni importin beta-1 0.0028 0.0086 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0125 0.0116
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.002 0.0185
Trypanosoma brucei heat shock protein, putative 0.0032 0.0105 0.0324
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0009 0.0062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0234 0.2622
Loa Loa (eye worm) ceramide kinase 0.0073 0.0327 0.0322
Echinococcus granulosus heat shock protein 90 0.0025 0.007 0.0066
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0124 0.012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.1607 0.1599
Loa Loa (eye worm) endoplasmin 0.0032 0.0105 0.0101
Schistosoma mansoni sphingosine kinase A B 0.1882 1 1
Plasmodium falciparum diacylglycerol kinase, putative 0.0073 0.0327 0.3897
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0133
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0009 0.0062
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0348 0.2522
Treponema pallidum phosphoglycerate kinase 0.0168 0.0831 1
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0133
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0052 0.0214 0.021
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0073 0.0327 0.1038
Echinococcus granulosus neuropeptide receptor A26 0.0453 0.236 0.2356
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0327 0.0322
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0047 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0043 0.0284
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0043 0.0043
Echinococcus granulosus heat shock protein 90 0.0032 0.0105 0.0101
Echinococcus granulosus zinc finger protein 0.0024 0.0064 0.0059
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.019 0.0185
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0282 0.2038
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0162 0.0508
Schistosoma mansoni ap endonuclease 0.0056 0.0234 0.0234
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0105 0.1217
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.019 0.0597
Brugia malayi jmjC domain containing protein 0.0066 0.029 0.2094
Entamoeba histolytica hypothetical protein, conserved 0.1882 1 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0056 0.0625
Schistosoma mansoni ferritin 0.0017 0.0027 0.0027
Trypanosoma brucei phosphoglycerate kinase 0.0062 0.0264 0.0835
Trichomonas vaginalis DNA polymerase eta, putative 0.0078 0.0354 0.2565
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0246
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0193 0.0189
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0124 0.0115
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0027 0.0018
Mycobacterium ulcerans hypothetical protein 0.0016 0.0021 0.0012
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0079 0.0075
Brugia malayi nuclear hormone receptor 0.002 0.0043 0.0284
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.3109 1
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0047 0.0043
Trypanosoma brucei unspecified product 0.0036 0.0127 0.0396
Echinococcus multilocularis heat shock protein 0.0032 0.0105 0.0101
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0033 0.035
Schistosoma mansoni apoferritin-2 0.0017 0.0027 0.0027
Brugia malayi glutaminase DH11.1 0.0268 0.1368 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0017
Brugia malayi isocitrate dehydrogenase 0.0016 0.0021 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Trichomonas vaginalis bmru protein, putative 0.0073 0.0327 0.2363
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0124 0.0115
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0234 0.1681
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0043 0.0039
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0234 0.0224
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0057 0.0387
Brugia malayi MH2 domain containing protein 0.0016 0.0022 0.0129
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1437 0.4614
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0048 0.0044
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0193 0.0189
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0073 0.0327 0.0327
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0057 0.0387
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0155 0.0487
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0086 0.0984
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0021 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0264 0.0835
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0354 0.1127
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0105 0.0324
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0124 0.012
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.1215 0.6435 0.6435
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.002 0.0015
Trichomonas vaginalis ferritin, putative 0.0017 0.0027 0.0167
Trichomonas vaginalis bmru protein, putative 0.0073 0.0327 0.2363
Loa Loa (eye worm) Smad1 0.0016 0.0022 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0246
Trypanosoma cruzi diacylglycerol kinase, putative 0.0073 0.0327 0.1038
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0105 0.0738
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0125 0.1462
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0043 0.0284
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0145
Schistosoma mansoni hypothetical protein 0.0063 0.027 0.027
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0121
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Mycobacterium tuberculosis Diacylglycerol kinase 0.0073 0.0327 0.0317
Giardia lamblia Grp94/Hsp90 0.0025 0.007 0.0605
Echinococcus granulosus importin subunit beta 1 0.0028 0.0086 0.0081
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0124 0.0386
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0048 0.0044
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0009 0.0016
Echinococcus multilocularis ferritin 0.0017 0.0027 0.0023
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0132 0.0132
Schistosoma mansoni cpg binding protein 0.0092 0.0427 0.0427
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0043 0.0043
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0124 0.0115
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0124 0.012
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0105 0.0324
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Brugia malayi Bromodomain containing protein 0.0079 0.0356 0.2576
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0112
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.1437 0.4614
Brugia malayi MH1 domain containing protein 0.0016 0.0022 0.0129
Echinococcus granulosus phosphoglycerate kinase 1 0.0168 0.0831 0.0827
Loa Loa (eye worm) hypothetical protein 0.012 0.0577 0.0573
Brugia malayi mbt repeat family protein 0.0048 0.0193 0.1387
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0043 0.0039
Leishmania major diacylglycerol kinase, putative 0.0073 0.0327 0.1038
Brugia malayi AMP-binding enzyme family protein 0.0048 0.019 0.1359
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.1015 0.1011
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0022 0.0018
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0282 0.0895
Brugia malayi Calcitonin receptor-like protein seb-1 0.0198 0.0995 0.7264
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0124 0.0879
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0043 0.0043
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0009 0.0016
Mycobacterium ulcerans phosphoglycerate kinase 0.0168 0.0831 0.0822
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0246
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.027 0.0266
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0121
Leishmania major pantothenate kinase subunit, putative 0.0013 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0039
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0021 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0021 0.0055
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0073 0.0327 0.2363
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0022 0.0022
Brugia malayi PHD-finger family protein 0.0029 0.0092 0.0641
Trichomonas vaginalis heat shock protein, putative 0.002 0.0039 0.0255
Onchocerca volvulus 0.0014 0.0009 0.0089
Brugia malayi jmjC domain containing protein 0.006 0.0254 0.1829
Plasmodium falciparum endoplasmin, putative 0.002 0.0039 0.042
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0161 0.0506
Schistosoma mansoni endoplasmin 0.0032 0.0105 0.0105
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0043 0.0043
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0229 0.1649
Leishmania major heat shock protein 83-1 0.0032 0.0105 0.0324
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0052 0.0214 0.021
Brugia malayi nuclear receptor NHR-88 0.002 0.0043 0.0284
Schistosoma mansoni hypothetical protein 0.0063 0.027 0.027

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) < 50 % Inhibition of recombinant Escherichia coli thymidine phosphorylase using thymidine as substrate at 50 uM by UV-spectrophotometric analysis relative to control ChEMBL. 23688695

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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