Detailed information for compound 1783248

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.192 | Formula: C16H14BrNO2
  • H donors: 1 H acceptors: 1 LogP: 3.22 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCc2c(N1)cc(cc2)OCc1cccc(c1)Br
  • InChi: 1S/C16H14BrNO2/c17-13-3-1-2-11(8-13)10-20-14-6-4-12-5-7-16(19)18-15(12)9-14/h1-4,6,8-9H,5,7,10H2,(H,18,19)
  • InChiKey: MHQJPPPGGALWQB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens monoamine oxidase B Starlite/ChEMBL References
Homo sapiens monoamine oxidase A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi amine oxidase, flavin-containing family protein monoamine oxidase B 520 aa 462 aa 19.7 %
Brugia malayi amine oxidase, flavin-containing family protein monoamine oxidase A 527 aa 474 aa 22.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.023 0.0879 0.1303
Schistosoma mansoni smdr2 0.0023 0.0039 0.0039
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Brugia malayi jmjC domain containing protein 0.0073 0.024 0.2321
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0069 0.291
Loa Loa (eye worm) histone methyltransferase 0.0054 0.0163 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0155 0.1494
Echinococcus multilocularis protoporphyrinogen oxidase 0.0051 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0043 0.012 0.012
Brugia malayi hypothetical protein 0.0025 0.0045 0.0437
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0155 0.0229
Trypanosoma brucei diacylglycerol kinase, putative 0.0065 0.021 0.086
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0095 0.0095
Schistosoma mansoni ap endonuclease 0.0037 0.0095 0.0095
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0405 0.3848
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0065 0.021 0.1939
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0019
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0113 0.0113
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0044 0.0471
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0019
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0051 0.015 0.021
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0038 0.0038
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0074 0.0284
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Brugia malayi nuclear receptor NHR-88 0.0052 0.0155 0.1494
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0069
Loa Loa (eye worm) hypothetical protein 0.0171 0.0641 0.095
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0105 0.0915
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0209 0.0792 0.0792
Echinococcus granulosus cathepsin l1 0.0016 0.0011 0.0011
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0039 0.0039
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0405 0.0585
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0155 0.1494
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0011 0.0011
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0039 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0155 0.0229
Echinococcus granulosus sphingosine kinase 1 0.1676 0.6747 0.6747
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0155 0.1494
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0321 0.0321
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0051 0.015 0.6976
Loa Loa (eye worm) hypothetical protein 0.0023 0.0039 0.0058
Leishmania major diacylglycerol kinase, putative 0.0065 0.021 0.086
Brugia malayi mbt repeat family protein 0.0051 0.0152 0.1467
Onchocerca volvulus 0.0051 0.015 0.162
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Trichomonas vaginalis abcb9, putative 0.0023 0.0039 0.0279
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Echinococcus multilocularis neuropeptide receptor A26 0.0938 0.3751 0.3751
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0242 0.0242
Toxoplasma gondii ABC1 family protein 0.0035 0.0087 0.0588
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0031
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0087 0.0744
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1609 0.6478 0.6478
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.021 0.086
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0155 0.0155
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0155 0.0155
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0048 0.0363
Echinococcus granulosus lamin 0.0026 0.0052 0.0052
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.011 1
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0011 0.0015
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.015 0.0604
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0095 0.8311
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.021 0.086
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0044 0.0065
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0181 0.0181
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0011 0.0111
Plasmodium falciparum zinc finger protein, putative 0.0021 0.0028 0.0833
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0171 0.0641 0.0641
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0045 0.0263
Leishmania major cathepsin L-like protease 0.0016 0.0011 0.0015
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0053 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Echinococcus multilocularis importin subunit beta 1 0.0028 0.006 0.006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0044 0.0065
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0011 0.0011
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0087 0.0105
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0021 0.0057
Echinococcus multilocularis 0.0051 0.015 0.015
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0039 0.0039
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0405 1
Echinococcus granulosus intermediate filament protein 0.0026 0.0052 0.0052
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0065 0.021 0.021
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0321 0.0476
Brugia malayi beta-lactamase 0.0035 0.0087 0.0841
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0032
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0039 0.0058
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0405 0.0585
Loa Loa (eye worm) glutaminase 2 0.0269 0.1036 0.1536
Trichomonas vaginalis bmru protein, putative 0.0065 0.021 0.1939
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0405 0.059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0056 0.0056
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0021 0.047
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0059
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0155 0.0155
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0067
Mycobacterium ulcerans monoamine oxidase 0.0051 0.015 0.021
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0069 0.3751
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0125 0.0885
Brugia malayi Smad1 0.0017 0.0012 0.0117
Loa Loa (eye worm) hypothetical protein 0.0241 0.0922 0.1367
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0288
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0044 0.0044
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0044 0.0423
Echinococcus multilocularis protein dispatched 1 0.0047 0.0137 0.0137
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0076 0.0112
Leishmania major DNA polymerase eta, putative 0.0019 0.0022 0.0059
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0048 0.0171
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0155 0.1675
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.1085 0.4591
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0125 0.1117
Mycobacterium ulcerans beta-lactamase 0.0035 0.0087 0.0118
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0012 0.0012
Trichomonas vaginalis bmru protein, putative 0.0065 0.021 0.1939
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0155 0.1494
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0405 0.0405
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0087 0.3816
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0039 0.0279
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0152 0.0152
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0013 0.0013
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0076 0.0076
Leishmania major p-glycoprotein 0.0023 0.0039 0.0134
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0051 0.015 0.2875
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Plasmodium vivax endoplasmin, putative 0.0032 0.0074 0.3178
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0008 0.0012
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0019
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0337 0.0484
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0022 0.002
Mycobacterium tuberculosis Conserved protein 0.0035 0.0087 0.0105
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus multilocularis cysteine protease 0.0016 0.0011 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0087 0.0105
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.0311
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0011 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.0641 0.6186
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0047 0.0057
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0155 0.0155
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.2355 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0052 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0011 0.0017
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0107
Echinococcus multilocularis endoplasmin 0.0025 0.0048 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0045 0.0159
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0087 0.0118
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0012
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0405 0.1693
Brugia malayi nuclear hormone receptor 0.0052 0.0155 0.1494
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0076 0.0088
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0012 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0019 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Brugia malayi isocitrate dehydrogenase 0.0032 0.0076 0.073
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0038 0.0266
Brugia malayi hypothetical protein 0.0016 0.001 0.0093
Trichomonas vaginalis diacylglycerol kinase, putative 0.0065 0.021 0.1939
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.1214 0.178
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0192
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0087 0.0105
Echinococcus granulosus Diacylglycerol kinase zeta 0.0065 0.021 0.021
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0181 0.0181
Brugia malayi nuclear receptor NHR-88 0.0024 0.0044 0.0423
Schistosoma mansoni hypothetical protein 0.0318 0.1235 0.1235
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0342
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0095 0.4231
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0267 0.0267
Schistosoma mansoni ferritin 0.0035 0.0087 0.0087
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0065 0.021 0.1939
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0011 0.0011
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.02 0.02
Schistosoma mansoni diacylglycerol kinase theta 0.0065 0.021 0.021
Echinococcus multilocularis dnaJ subfamily C 6 0.0059 0.0185 0.0185
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0135 0.1306
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0039 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0047 0.0449
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0011 0.012
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0152 0.0152
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0047 0.0449
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0047 0.0057
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0069 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Echinococcus granulosus expressed conserved protein 0.0091 0.0314 0.0314
Brugia malayi hypothetical protein 0.0241 0.0922 0.8904
Schistosoma mansoni endoplasmin 0.0032 0.0074 0.0074
Trichomonas vaginalis diacylglycerol kinase, putative 0.0065 0.021 0.1939
Plasmodium falciparum importin beta, putative 0.0028 0.006 0.2439
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.2355 1
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0087 0.1138
Brugia malayi MH2 domain containing protein 0.0244 0.0934 0.9017
Echinococcus granulosus GPCR family 2 0.0079 0.0267 0.0267
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0013 0.0013
Loa Loa (eye worm) acetyltransferase 0.0151 0.0559 0.0829
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0065 0.021 0.021
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0045 0.0159
Schistosoma mansoni hypothetical protein 0.0079 0.0267 0.0267
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Schistosoma mansoni hypothetical protein 0.0065 0.021 0.021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Plasmodium vivax diacylglycerol kinase, putative 0.0065 0.021 1
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.2856 0.4226
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0012 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0267 0.0396
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0199 0.0815
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Brugia malayi ABC transporter family protein 0.0023 0.0039 0.0381
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.0963 0.9296
Schistosoma mansoni hypothetical protein 0.0079 0.0267 0.0267
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0342
Schistosoma mansoni myst-related protein 0.0021 0.0028 0.0028
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0559 0.5395
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0044 0.0044
Plasmodium vivax diacylglycerol kinase, putative 0.0065 0.021 1
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0095 0.0824
Schistosoma mansoni hypothetical protein 0.0303 0.1174 0.1174
Schistosoma mansoni DNA polymerase eta 0.0019 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0199 0.0815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0241 0.0922 0.1367
Chlamydia trachomatis protoporphyrinogen oxidase 0.0051 0.015 1
Plasmodium falciparum endoplasmin, putative 0.002 0.0024 0.0646
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0039 0.0041
Schistosoma mansoni microtubule-associated protein tau 0.2048 0.8259 0.8259
Leishmania major UDP-galactopyranose mutase 0.0051 0.015 0.0604
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0044 0.0044
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0012
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0044 0.0065
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0095 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0048 0.0041
Onchocerca volvulus 0.0023 0.0039 0.0423
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0284 0.1175
Brugia malayi RNA, U transporter 1 0.0081 0.0272 0.2626
Schistosoma mansoni endoplasmin 0.0032 0.0074 0.0074
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0044
Mycobacterium ulcerans hypothetical protein 0.1676 0.6747 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0405 1
Echinococcus granulosus heat shock protein 0.0032 0.0074 0.0074
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0124
Loa Loa (eye worm) hypothetical protein 0.0051 0.0151 0.0224
Schistosoma mansoni diacylglycerol kinase theta 0.0065 0.021 0.021
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0069 0.291
Brugia malayi SWIRM domain containing protein 0.0051 0.015 0.1445
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0069 0.0448
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.0209
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0048 0.006
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0047 0.0057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0087 0.0087
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0056 0.0056
Brugia malayi hypothetical protein 0.0024 0.0044 0.0423
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0155 0.0155
Plasmodium vivax hypothetical protein, conserved 0.0051 0.015 0.6976
Schistosoma mansoni survival motor neuron protein 0.0047 0.0135 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0155 0.1494
Schistosoma mansoni sphingosine kinase A B 0.1676 0.6747 0.6747
Onchocerca volvulus 0.0024 0.0044 0.0471
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Schistosoma mansoni zinc finger protein 0.0024 0.0044 0.0044
Toxoplasma gondii exonuclease III APE 0.0037 0.0095 0.0652
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0095 0.4231
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0039 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0087 0.0744
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0113 0.0113
Echinococcus granulosus geminin 0.051 0.2013 0.2013
Brugia malayi hypothetical protein 0.0027 0.0056 0.0538
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0181 0.1744
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0181 0.0181
Brugia malayi Eye-specific diacylglycerol kinase 0.0065 0.021 0.2023
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0039 0.0039
Brugia malayi Cytochrome P450 family protein 0.0016 0.0008 0.0076
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0075
Onchocerca volvulus 0.0035 0.0087 0.094
Echinococcus granulosus snurportin 1 0.0303 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0095 0.1324
Leishmania major hypothetical protein, conserved 0.0025 0.0045 0.0159
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0039 0.0039
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Loa Loa (eye worm) CXXC zinc finger family protein 0.0174 0.0651 0.0965
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0022 0.0007
Leishmania major cathepsin L-like protease 0.0063 0.0199 0.0815
Schistosoma mansoni ran 0.0021 0.0029 0.0029
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0152 0.0225
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0321 0.0321
Trichomonas vaginalis sphingosine kinase, putative 0.0065 0.021 0.1939
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0048 0.0047
Onchocerca volvulus 0.0026 0.0052 0.0563
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.0163 0.0163
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0087 0.0105
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0879 0.0879
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0125 0.0125
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0039 0.0039
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0039 0.0039
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0559 0.0559
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.0934 0.1385
Brugia malayi heat shock protein 90 0.0032 0.0074 0.0719
Onchocerca volvulus 0.0174 0.0651 0.7053
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0076 0.073
Echinococcus granulosus microtubule associated protein 2 0.2048 0.8259 0.8259
Toxoplasma gondii histone lysine-specific demethylase 0.0051 0.015 0.1075
Echinococcus multilocularis dna polymerase eta 0.0019 0.0022 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0155 0.0155
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0022 0.0015
Trypanosoma cruzi Sphingosine kinase 0.0065 0.021 0.086
Loa Loa (eye worm) hypothetical protein 0.0042 0.0113 0.0168
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.02 0.02
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0048 0.0171
Schistosoma mansoni coup transcription factor 0.0052 0.0155 0.0155
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.021 0.0294
Trypanosoma brucei ISWI complex protein 0.0018 0.0019 0.0047
Schistosoma mansoni multidrug resistance protein 0.0023 0.0039 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0155 0.0155
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0405 0.3848
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0542 0.0542
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0337 0.3257
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Plasmodium falciparum heat shock protein 90 0.0032 0.0074 0.3178
Leishmania major sphingosine kinase A, B, putative 0.0065 0.021 0.086
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1085 0.4591
Brugia malayi nuclear receptor NHR-67 0.0024 0.0044 0.0423
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.015 0.015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0155 0.0155
Onchocerca volvulus 0.0024 0.0044 0.0471
Echinococcus multilocularis Diacylglycerol kinase theta 0.0065 0.021 0.021
Brugia malayi amine oxidase, flavin-containing family protein 0.0051 0.015 0.1445
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0048 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0076
Schistosoma mansoni ferritin light chain 0.0035 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Trypanosoma brucei Sphingosine kinase 0.0065 0.021 0.086
Giardia lamblia Grp94/Hsp90 0.0025 0.0048 0.2974
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.024 0.024
Trichomonas vaginalis abcb9, putative 0.0023 0.0039 0.0279
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0013 0.0068
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0031
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0405 0.0585
Schistosoma mansoni hypothetical protein 0.051 0.2013 0.2013
Schistosoma mansoni lamin 0.0026 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0069
Trichomonas vaginalis hypothetical protein 0.0021 0.0031 0.0192
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0152 0.0152
Brugia malayi hypothetical protein 0.0073 0.0242 0.2334
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0022 0.0022
Brugia malayi SET domain containing protein 0.0014 0 0.0004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0021 0.0006
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0044 0.0044
Loa Loa (eye worm) ceramide kinase 0.0065 0.021 0.0311
Schistosoma mansoni jumonji domain containing protein 0.0063 0.02 0.02
Trypanosoma brucei unspecified product 0.0019 0.0022 0.0059
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0048 0.0363
Loa Loa (eye worm) hypothetical protein 0.0174 0.0653 0.0967
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0155 0.0229
Echinococcus granulosus lamin dm0 0.0026 0.0052 0.0052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0155 0.0155
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0051 0.015 0.015
Brugia malayi N-terminal motif family protein 0.0174 0.0653 0.6299
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0043 0.012 0.012
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0039 0.0041
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0152 0.0152
Onchocerca volvulus 0.0065 0.021 0.2269
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0021 0.047
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0048 0.0363
Mycobacterium ulcerans hypothetical protein 0.0025 0.0047 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0199 0.0815
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0022
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0012 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0095 0.0373
Echinococcus multilocularis heat shock protein 0.0032 0.0074 0.0074
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0155 0.0155
Onchocerca volvulus Ceramide kinase 1 homolog 0.0065 0.021 0.2269
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0155 0.1494
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0155 0.1494
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0039 0.0279
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0074 0.3178
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Onchocerca volvulus 0.0016 0.0011 0.012
Loa Loa (eye worm) diacylglycerol kinase 2 0.0065 0.021 0.0311
Brugia malayi hypothetical protein 0.0065 0.021 0.2023
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0012
Echinococcus multilocularis lamin 0.0026 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0065 0.021 0.086
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0095 0.0373
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0065 0.021 0.1541
Schistosoma mansoni amine oxidase 0.0051 0.015 0.015
Brugia malayi hypothetical protein 0.0051 0.015 0.1445
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0087 0.0118
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0087 0.0087
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0008 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0076 0.0288
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0029 0.0139
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Brugia malayi mbt repeat family protein 0.0051 0.0152 0.1467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0076 0.0076
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus granulosus phd:f box containing protein 0.0017 0.0013 0.0013
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0035 0.0087 0.8321
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0155 0.1494
Toxoplasma gondii diacylglycerol kinase, putative 0.0065 0.021 0.1541
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0039 0.0134
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0011 0.0007
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0013 0.0011
Trichomonas vaginalis endoplasmin, putative 0.002 0.0024 0.0131
Loa Loa (eye worm) fibroinase 0.0016 0.0011 0.0017
Echinococcus granulosus endoplasmin 0.0025 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0077
Mycobacterium ulcerans lipase LipD 0.0035 0.0087 0.0118
Schistosoma mansoni hypothetical protein 0.2477 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0155 0.0155
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.021 0.0294
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0105 0.0915
Schistosoma mansoni thyroid hormone receptor 0.0052 0.0155 0.0155
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0044 0.0423
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.0209
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0013 0.0013
Echinococcus granulosus neuropeptide receptor A26 0.0938 0.3751 0.3751
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0087 0.113
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0083
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0044 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0056 0.0538
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0155 0.1494
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0125 0.5746
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0594 0.2355 1
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0065 0.021 0.086
Echinococcus multilocularis cysteine protease 0.0016 0.0011 0.0011
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0343 0.0343
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0022 0.0106
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0076 0.0499
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0155 0.0155
Trichomonas vaginalis helicase, putative 0.0039 0.0105 0.0915
Loa Loa (eye worm) beta-lactamase 0.0035 0.0087 0.0129
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0038 0.0266
Leishmania major GTP-binding protein, putative 0.0021 0.0029 0.0092
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0181 0.0181
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0092
Trichomonas vaginalis heat shock protein, putative 0.002 0.0024 0.0131
Onchocerca volvulus 0.0015 0.0006 0.0064
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0095 0.092
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0087 0.0337
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0337 0.0337
Leishmania major mitochondrial DNA polymerase beta 0.0594 0.2355 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0125 0.1117
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0874
Echinococcus multilocularis microtubule associated protein 2 0.2048 0.8259 0.8259
Echinococcus granulosus smad 0.0017 0.0012 0.0012
Brugia malayi MH2 domain containing protein 0.0017 0.0012 0.0117
Onchocerca volvulus 0.0035 0.0087 0.094
Echinococcus multilocularis expressed conserved protein 0.0091 0.0314 0.0314
Loa Loa (eye worm) ctsf protein 0.0016 0.0011 0.0017
Schistosoma mansoni multidrug resistance protein 0.0023 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0155 0.1494
Onchocerca volvulus Huntingtin homolog 0.0241 0.0922 1
Echinococcus granulosus Diacylglycerol kinase theta 0.0065 0.021 0.021
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0051 0.015 0.015
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0267 0.0267
Leishmania major cathepsin L-like protease 0.0016 0.0011 0.0015
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0242 0.0242
Leishmania major cathepsin L-like protease 0.0063 0.0199 0.0815
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0039 0.0058
Mycobacterium tuberculosis Conserved protein 0.0035 0.0087 0.0105
Brugia malayi DnaJ domain containing protein 0.0059 0.0185 0.1785
Schistosoma mansoni apoferritin-2 0.0035 0.0087 0.0087
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0267 0.0267
Leishmania major diacylglycerol kinase-like protein 0.0065 0.021 0.086
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0076
Echinococcus multilocularis dnaJ subfamily B 0.2477 1 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0074 0.0284
Brugia malayi MH1 domain containing protein 0.0017 0.0012 0.0117
Leishmania major cathepsin L-like protease 0.0063 0.0199 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0155 0.0155
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0021
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.011 0.0147
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0155 0.0155
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0155 0.0155
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0039 0.141
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0039 0.0279
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0047 0.0165
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0044 0.0423
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Schistosoma mansoni ap endonuclease 0.0037 0.0095 0.0095
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0039 0.0279
Echinococcus multilocularis GPCR, family 2 0.0079 0.0267 0.0267
Schistosoma mansoni importin beta-1 0.0028 0.006 0.006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0076 0.3235
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0065 0.021 0.021
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0065 0.021 0.1541
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi diacylglycerol kinase 0.0065 0.021 0.2023
Brugia malayi conserved hypotetical protein 0.0024 0.0044 0.0423
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0074 0.0284
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0047 0.0052
Schistosoma mansoni apoferritin-2 0.0035 0.0087 0.0087
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0044 0.0044
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0013 0.0013
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0076
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0039 0.0041
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0029 0.0905
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0242 0.0242
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0047 0.0052
Toxoplasma gondii hypothetical protein 0.0096 0.0333 0.2504
Trichomonas vaginalis ran, putative 0.0021 0.0029 0.0181
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0044 0.0044
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.021 0.0294
Schistosoma mansoni myst-related protein 0.0021 0.0028 0.0028
Schistosoma mansoni smad 0.0017 0.0012 0.0012
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0113 0.0113
Echinococcus multilocularis thyroid hormone receptor alpha 0.0052 0.0155 0.0155
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0506 0.0506
Mycobacterium ulcerans diacylglycerol kinase 0.0065 0.021 0.0299
Onchocerca volvulus 0.0016 0.0011 0.012
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.015 0.015
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0044 0.0423
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0405 0.0578
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0267 0.2576
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0022 0.0059
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.2856 0.4226
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.0311
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0074 0.0284
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0051 0.015 0.6976
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0074 0.011
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0022 0.0007
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0288
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0022 0.002
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Brugia malayi hypothetical protein 0.0024 0.0044 0.0423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Onchocerca volvulus 0.0016 0.0011 0.012
Loa Loa (eye worm) hypothetical protein 0.0251 0.0963 0.1428
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0155 0.0229
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0013 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0045 0.1704
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0074 0.049
Schistosoma mansoni ferritin 0.0035 0.0087 0.0087
Brugia malayi Diacylglycerol kinase protein 2 0.0065 0.021 0.2023
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0087 0.0118
Trichomonas vaginalis abcb9, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) hypothetical protein 0.0058 0.0181 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0405 0.0601
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0021
Echinococcus multilocularis geminin 0.051 0.2013 0.2013
Brugia malayi glutaminase DH11.1 0.0269 0.1036 1
Echinococcus granulosus heat shock protein 90 0.0025 0.0048 0.0048
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0044 0.0471
Leishmania major hypothetical protein, conserved 0.0017 0.0013 0.0021
Trichomonas vaginalis ferritin, putative 0.0035 0.0087 0.0747
Schistosoma mansoni nuclear receptor 0.0024 0.0044 0.0044
Echinococcus multilocularis multidrug resistance protein 1 0.0016 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0073 0.0242 0.0242
Brugia malayi phosphofructokinase 0.0113 0.0405 0.3913
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0011 0.0011
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0011 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0047 0.0057
Brugia malayi diacylglycerol kinase 0.0065 0.021 0.2023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.024 0.024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0267 0.2576
Mycobacterium tuberculosis Conserved protein 0.1676 0.6747 1
Brugia malayi nuclear receptor RXR 0.0027 0.0056 0.0538
Brugia malayi CHE-14 protein 0.0042 0.0113 0.1093
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0045 0.0159
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0074 0.0093
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0038 0.0266
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0083
Echinococcus multilocularis smad 0.0017 0.0012 0.0012
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0039 0.0039
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0155 0.0155
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0039 0.0039
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0405 0.1693
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0012 0.0018
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0051 0.015 0.6976
Echinococcus multilocularis ferritin 0.0035 0.0087 0.0087
Onchocerca volvulus 0.0016 0.0011 0.012
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0089
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0039 0.0041
Leishmania major importin beta-1 subunit, putative 0.0023 0.0038 0.0129
Brugia malayi Endoplasmin precursor 0.0032 0.0074 0.0719
Schistosoma mansoni lamin 0.0026 0.0052 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0051 0.015 0.6976
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0155 0.1494
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0209 0.0792 0.0792
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0069 0.291
Trichomonas vaginalis taga, putative 0.0023 0.0039 0.0279
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0011 0.0011
Echinococcus granulosus importin subunit beta 1 0.0028 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0113 0.0999
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0113 0.0168
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0284 0.1175
Onchocerca volvulus 0.0025 0.0047 0.0501
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0152 0.1644
Schistosoma mansoni amine oxidase 0.0051 0.015 0.015
Brugia malayi 6-phosphofructokinase 0.0113 0.0405 0.3913
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0047 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Entamoeba histolytica hypothetical protein 0.0021 0.0028 0.0025
Mycobacterium ulcerans dehydrogenase 0.0051 0.015 0.021
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0061 0.0193 0.141
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0069 0.0086
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0069 0.291
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0155 0.0155
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0074 0.0284
Plasmodium falciparum diacylglycerol kinase, putative 0.0065 0.021 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0047 0.0057
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0045 0.1704
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0087 0.0105
Onchocerca volvulus 0.0035 0.0087 0.094
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0053 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0321 0.0321
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0199 0.0815
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0076 0.0499
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0321 0.3099
Schistosoma mansoni hypothetical protein 0.0079 0.0267 0.0267
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0069 0.0569
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0155 0.0229
Brugia malayi 6-phosphofructokinase 0.0114 0.0406 0.3923
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0038 0.0129
Schistosoma mansoni heat shock protein 0.0032 0.0074 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Brugia malayi Ceramide kinase 0.0065 0.021 0.2023
Leishmania major hypothetical protein, conserved 0.0035 0.0087 0.0337
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0022 0.0106
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0155 0.0155
Trypanosoma cruzi diacylglycerol kinase, putative 0.0065 0.021 0.086
Brugia malayi CXXC zinc finger family protein 0.0174 0.0651 0.6281
Brugia malayi MH2 domain containing protein 0.0017 0.0012 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0087 0.0744
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0405 0.0601
Trypanosoma cruzi Sphingosine kinase 0.0065 0.021 0.086
Schistosoma mansoni cpg binding protein 0.0184 0.0691 0.0691
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0155 0.0155
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0039 0.0034
Entamoeba histolytica hypothetical protein, conserved 0.1676 0.6747 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0047 0.0057
Brugia malayi MH1 domain containing protein 0.0017 0.0012 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.0022
Mycobacterium ulcerans hypothetical protein 0.0313 0.1214 0.179
Echinococcus granulosus ceramide kinase 0.0065 0.021 0.021
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0039 0.0041
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0065 0.021 0.086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0069
Schistosoma mansoni hypothetical protein 0.051 0.2013 0.2013
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.024 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0078
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0155 0.0155
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0087 0.0105
Echinococcus granulosus expressed protein 0.0035 0.0087 0.0087
Schistosoma mansoni cpg binding protein 0.0184 0.0691 0.0691
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Schistosoma mansoni heat shock protein 0.0032 0.0074 0.0074
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0048 0.0171
Schistosoma mansoni nuclear receptor 0.0024 0.0044 0.0044
Echinococcus multilocularis lamin dm0 0.0026 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0181 0.0181
Schistosoma mansoni patched 1 0.0042 0.0113 0.0113
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0013 0.0013
Onchocerca volvulus 0.0051 0.0152 0.1644
Echinococcus multilocularis musashi 0.0026 0.0052 0.0052
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0039 0.0041
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0321 0.0321
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0087 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.015 0.0198
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0074 0.0284
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0087 0.0087
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0074 0.0284
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0047 0.0057
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0854 0.1245
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0074 0.0621
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.0934 0.1385
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0321 0.0321
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0087 0.0129
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0506 0.0506
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0039 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Onchocerca volvulus 0.0026 0.0052 0.0563
Loa Loa (eye worm) MBCTL1 0.0058 0.0181 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0155 0.1494
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.006 0.0376
Trichomonas vaginalis esterase, putative 0.0035 0.0087 0.0744
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.015 0.0604
Leishmania major cathepsin L-like protease 0.0016 0.0011 0.0015
Brugia malayi ecdysteroid receptor 0.0052 0.0155 0.1494
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0013 0.0013
Echinococcus granulosus heat shock protein 90 0.0032 0.0074 0.0074
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0029 0.0029
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0056 0.0056
Echinococcus granulosus dna polymerase eta 0.0019 0.0022 0.0022
Plasmodium falciparum diacylglycerol kinase, putative 0.0065 0.021 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0321 0.0321
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0155 0.1675
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0174 0.0653 0.7074
Loa Loa (eye worm) Smad1 0.0017 0.0012 0.0018
Trichomonas vaginalis glutaminase, putative 0.0269 0.1036 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0177 0.0721
Echinococcus granulosus ferritin 0.0035 0.0087 0.0087
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0039 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0044 0.0044
Schistosoma mansoni ferritin light chain 0.0035 0.0087 0.0087
Brugia malayi F/Y-rich N-terminus family protein 0.0053 0.016 0.1548
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi hypothetical protein 0.023 0.0879 0.8485
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0065 0.021 0.086
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0039 0.0279
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0074 0.049
Entamoeba histolytica hypothetical protein 0.0023 0.0038 0.0039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.0163 0.0163
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0011 0.012
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0044 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0056 0.0056
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0095 0.013
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0039 0.0217
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0043 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0044 0.0423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0044 0.0423
Loa Loa (eye worm) DnaJ domain-containing protein 0.0059 0.0185 0.0274
Brugia malayi Cathepsin L-like precursor 0.0016 0.0011 0.0111
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.0963 0.9296
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0052 0.0505
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0879 0.0879
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0031 0.0192
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0039 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0087 0.0337
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0047 0.0165
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0043 0.012 0.012
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0155 0.0155
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0155 0.1494
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.015 0.0198
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0022 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0044 0.0044
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0069 0.0448
Brugia malayi beta-lactamase family protein 0.0035 0.0087 0.0841
Trichomonas vaginalis sphingosine kinase, putative 0.0065 0.021 0.1939
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0145 0.0583
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0155 0.0155
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0076 0.3235
Mycobacterium tuberculosis Diacylglycerol kinase 0.0065 0.021 0.0287
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0095 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0087 0.0744
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0051 0.0152 0.0225
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0155 0.0155
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0048 0.2974
Plasmodium falciparum protoporphyrinogen oxidase 0.0051 0.015 0.6976
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0051 0.015 0.015
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0065 0.021 0.0311
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0039 0.0279
Schistosoma mansoni ferritin 0.0035 0.0087 0.0087
Echinococcus multilocularis sphingosine kinase 1 0.1676 0.6747 0.6747
Loa Loa (eye worm) DR-78 0.0024 0.0044 0.0065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0095 0.0373
Loa Loa (eye worm) cysteine protease 0.0016 0.0011 0.0017
Echinococcus granulosus dnaJ subfamily C 6 0.0059 0.0185 0.0185
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0029 0.0029
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0069 0.5358
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0059
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0047 0.0044
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0155 0.0229
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0039 0.141
Mycobacterium ulcerans glutaminase 0.0269 0.1036 0.1526
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0021 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.0963 0.1428
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0045 0.1704
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0124
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0284 0.1175
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0011 0.012
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Brugia malayi Cytochrome P450 family protein 0.0016 0.0008 0.0076
Trypanosoma cruzi ISWI complex protein 0.0018 0.0019 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0012 0.0018
Leishmania major cathepsin L-like protease 0.0016 0.0011 0.0015
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0095 0.0141
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0155 0.1675
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0405 0.0405
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0069 0.0591
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Brugia malayi beta-lactamase family protein 0.0035 0.0087 0.0841
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Schistosoma mansoni hypothetical protein 0.0047 0.0135 0.0135
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0155 0.0229
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Echinococcus granulosus cpg binding protein 0.0184 0.0691 0.0691
Brugia malayi hypothetical protein 0.0027 0.0056 0.0538
Mycobacterium leprae Probable lipase LipE 0.0035 0.0087 0.113
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.0022
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0284
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.024 0.0356
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0039 0.0279
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0087 0.0105
Brugia malayi jmjC domain containing protein 0.0063 0.02 0.1933
Echinococcus granulosus Smad4 0.0017 0.0012 0.0012
Leishmania major DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0044 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0039 0.0217
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0155 0.1494
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0039 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0095 0.0373
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0065 0.021 0.086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Echinococcus granulosus neuropeptide s receptor 0.0938 0.3751 0.3751
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0092
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0047 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0288
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0065 0.021 0.021
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0284 0.1175
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0011 0.0011
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Echinococcus multilocularis snurportin 1 0.0303 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Loa Loa (eye worm) hypothetical protein 0.0079 0.0267 0.0396
Echinococcus multilocularis neuropeptide s receptor 0.0938 0.3751 0.3751
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0087 0.0337
Schistosoma mansoni hypothetical protein 0.0079 0.0267 0.0267
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0125 0.0885
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0083
Loa Loa (eye worm) hypothetical protein 0.0052 0.0155 0.0229
Onchocerca volvulus 0.0016 0.0011 0.012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0358 0.1491
Brugia malayi tailless protein 0.0024 0.0044 0.0423
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0013 0.0013
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0087 0.0744
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1085 0.4591
Schistosoma mansoni cpg binding protein 0.0174 0.0651 0.0651
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0667 0.2651 0.3914
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.021 0.0294
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0905
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0155 0.1494
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0095 0.0124
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0044 0.0044
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0337 0.0337
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Schistosoma mansoni ferritin 0.0035 0.0087 0.0087
Echinococcus multilocularis cpg binding protein 0.0184 0.0691 0.0691
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0405 0.3848
Brugia malayi steroid hormone receptor 0.0052 0.0155 0.1494
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0155 0.1494
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0003
Brugia malayi Importin beta-1 subunit 0.0028 0.006 0.0577
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0069 0.0569
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0039 0.0039
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0022 0.0059
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0011 0.0007
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0074 0.5956
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0044 0.0044
Mycobacterium tuberculosis Conserved protein 0.0035 0.0087 0.0105
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0342
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0022 0.0059
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0039 0.1444
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0087 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0222
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.011 0.4987
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0405 0.3848
Brugia malayi nuclear receptor RXR 0.0024 0.0044 0.0423
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0369 0.1442 0.1442
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0559 0.0559
Plasmodium vivax JmjC domain containing protein 0.0017 0.0013 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0011 0.0007
Onchocerca volvulus Huntingtin homolog 0.0241 0.0922 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0076 0.0288
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0047 0.0052
Schistosoma mansoni thyroid hormone receptor 0.0052 0.0155 0.0155
Schistosoma mansoni glutaminase 0.0269 0.1036 0.1036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Loa Loa (eye worm) glutaminase 0.0269 0.1036 0.1536
Brugia malayi nuclear hormone receptor 0.0024 0.0044 0.0423
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0056 0.0538
Entamoeba histolytica Ran family GTPase 0.0021 0.0029 0.0027
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0039 0.0039
Echinococcus multilocularis ceramide kinase 0.0065 0.021 0.021
Echinococcus multilocularis heat shock protein 90 0.0025 0.0048 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Onchocerca volvulus 0.0052 0.0155 0.1675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0087 0.0841
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0065 0.021 0.021
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0095 0.0117
Schistosoma mansoni multidrug resistance protein 0.0023 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0083
Mycobacterium ulcerans oxidoreductase 0.0051 0.015 0.021
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0405 0.1693
Toxoplasma gondii histone lysine methyltransferase SET1 0.0333 0.1297 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.006 0.0221
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0105 0.0915
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0405 0.0601
Schistosoma mansoni intermediate filament proteins 0.0026 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.1676 0.6747 1
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0152 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0199 0.0815
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0056 0.0083
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0152 0.0152
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0069 0.3751
Loa Loa (eye worm) hypothetical protein 0.0097 0.0337 0.05
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0051 0.015 0.6976
Echinococcus multilocularis protein patched 0.0042 0.0113 0.0113
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0087 0.0087
Trypanosoma brucei heat shock protein, putative 0.0032 0.0074 0.0284
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.1174 0.174
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0052 0.0077
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0124
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0065
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0342
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0038 0.0038
Echinococcus multilocularis expressed protein 0.0035 0.0087 0.0087
Echinococcus granulosus dna polymerase kappa 0.0019 0.0022 0.0022
Trichomonas vaginalis protein kinase inhibitor, putative 0.0059 0.0185 0.1698
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0076 0.0076
Leishmania major cathepsin L-like protease 0.0016 0.0011 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0008 0.0012
Trypanosoma cruzi diacylglycerol kinase, putative 0.0065 0.021 0.086
Leishmania major heat shock protein 83-1 0.0032 0.0074 0.0284
Echinococcus multilocularis Smad4 0.0017 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.021 0.1939
Schistosoma mansoni Smad4 0.0017 0.0012 0.0012
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0039 0.0279
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0155 0.0155
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0039 0.0279
Echinococcus multilocularis heat shock protein 90 0.0032 0.0074 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Brugia malayi intermediate filament protein 0.0026 0.0052 0.0505
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0044 0.0044
Onchocerca volvulus 0.0016 0.0011 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0152 0.0152
Plasmodium vivax importin-beta 2, putative 0.0028 0.006 0.2439
Schistosoma mansoni hypothetical protein 0.0059 0.0185 0.0185
Brugia malayi multidrug resistance protein 3 0.0023 0.0039 0.0381
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0087 0.1101
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0267 0.0267
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0107
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.0065 0.021 0.086
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0011 0.0007
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0013 0.0013
Mycobacterium ulcerans hypothetical protein 0.0035 0.0087 0.0118
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0013 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.006 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0155 0.0229
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0087 0.0105
Brugia malayi ecdysone receptor 0.0024 0.0044 0.0423
Loa Loa (eye worm) endoplasmin 0.0032 0.0074 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0074 0.0284
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0065 0.021 0.1939
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0155 0.0155
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0076
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0047 0.0165
Schistosoma mansoni ran 0.0021 0.0029 0.0029
Schistosoma mansoni sphingoid long chain base kinase 0.1676 0.6747 0.6747
Onchocerca volvulus 0.0016 0.0011 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0105 0.0915
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0321 0.0321
Echinococcus granulosus mixed lineage leukemia protein mll 0.0043 0.012 0.012
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0013 0.0011
Onchocerca volvulus 0.0047 0.0135 0.1463
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0074 0.0093

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 36 % Reversible inhibition of recombinant human MAO-B using kynuramine as substrate assessed as residual activity at 100 times IC50 preincubated for 30 mins followed by 100 fold dilution measured after 20 mins by fluorescence spectrophotometry relative to control ChEMBL. 24012182
Activity (binding) = 70 % Reversible inhibition of recombinant human MAO-B using kynuramine as substrate assessed as residual activity at 10 times IC50 preincubated for 30 mins followed by 100 fold dilution measured after 20 mins by fluorescence spectrophotometry relative to control ChEMBL. 24012182
IC50 (binding) = 8.17 nM Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric method LITERATURE. 27692996
IC50 (binding) = 0.0029 uM Inhibition of recombinant human MAO-B assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline after 20 mins by fluorescence spectrophotometry ChEMBL. 24012182
IC50 (binding) = 7.98 uM Inhibition of recombinant human MAO-A assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline after 20 mins by fluorescence spectrophotometry ChEMBL. 24012182
IC50 (binding) = 49.17 uM Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric method LITERATURE. 27692996
Ki (binding) = 0.0027 uM Reversible competitive inhibition of recombinant human MAO-B using kynuramine as substrate assessed as formation of 4-hydroxyquinoline by Lineweaver-Burk plot analysis ChEMBL. 24012182

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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