Detailed information for compound 2069217

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.366 | Formula: C17H21N3O4
  • H donors: 3 H acceptors: 3 LogP: 0.91 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ncccc1CNC(=O)NCC(c1ccccc1OC)O
  • InChi: 1S/C17H21N3O4/c1-23-15-8-4-3-7-13(15)14(21)11-20-17(22)19-10-12-6-5-9-18-16(12)24-2/h3-9,14,21H,10-11H2,1-2H3,(H2,19,20,22)
  • InChiKey: QRLJPEVVMJJHNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.0038
Schistosoma mansoni tar DNA-binding protein 0.007 0.0115 0.0235
Onchocerca volvulus 0.001 0.0001 0.0001
Brugia malayi Variant SH3 domain containing protein 0.001 0.0001 0.0001
Leishmania major phospholipase c-like protein 0.0063 0.0101 0.0599
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus multilocularis sodium channel protein 0.0023 0.0026 0.0124
Loa Loa (eye worm) Plekhf2 protein 0.001 0.0001 0.0001
Echinococcus multilocularis shaker cognate 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0026 0.0026
Brugia malayi Oxysterol binding protein 0.001 0.0001 0.0001
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.002 0.0021 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0068 0.0112 1
Echinococcus multilocularis transfer RNA-Gly 0.0023 0.0026 0.0124
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0026 0.0124
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.001 0.0002 0.0008
Trypanosoma brucei rac serine-threonine kinase, putative 0.0146 0.0259 0.1044
Echinococcus granulosus Protein kinase C brain isozyme 0.0074 0.0123 0.0589
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.001 0.0001 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Trichomonas vaginalis alpha-glucosidase, putative 0.001 0.0002 0.0001
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0003 0.0081
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.001 0.0002 0.5
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0009 0.0000016117 0.0000033059
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0004 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Plasmodium vivax protein kinase Crk2 0.0013 0.0006 0.0426
Echinococcus multilocularis expressed conserved protein 0.0079 0.0132 0.0628
Echinococcus granulosus oxysterol binding protein 9 0.001 0.0001 0.0004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.001 0.0002 0.0004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0026 0.0026
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0026 0.0124
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0012 0.0012
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0023 0.0026 0.0026
Plasmodium vivax hypothetical protein, conserved 0.001 0.0001 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus granulosus cyclin dependent kinase 0.0013 0.0006 0.003
Entamoeba histolytica protein kinase, putative 0.0011 0.0003 0.0056
Schistosoma mansoni voltage-gated cation channel 0.0023 0.0026 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0004
Onchocerca volvulus 0.001 0.0001 0.0001
Echinococcus multilocularis voltage dependent calcium channel 0.0023 0.0026 0.0124
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0023 0.0026 0.0124
Echinococcus granulosus pleckstrin y domain containing family A 0.001 0.0001 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.0026 0.0124
Brugia malayi p70 ribosomal S6 kinase beta 0.0136 0.024 0.024
Trypanosoma brucei unspecified product 0.0029 0.0038 0.015
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0006 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Plasmodium falciparum calcium-dependent protein kinase 7 0.0011 0.0003 0.0225
Leishmania major dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0005
Echinococcus granulosus Glutaredoxin protein 5 0.0086 0.0146 0.0699
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0006 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0034 0.0136
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0009 0.0000016117 0.0000076971
Echinococcus granulosus lysosomal alpha glucosidase 0.0089 0.0151 0.0721
Echinococcus multilocularis sodium leak channel non selective protein 0.0023 0.0026 0.0124
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0013 0.0006 0.0033
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0063 0.5569
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0091 0.0154 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0012 0.0011
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0011 0.0003 0.001
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Toxoplasma gondii AGC kinase 0.0136 0.024 1
Brugia malayi phospholipase C homolog 0.0063 0.0102 0.0102
Loa Loa (eye worm) oxysterol binding protein 0.001 0.0001 0.0001
Echinococcus granulosus protein kinase c epsilon type 0.0056 0.0088 0.042
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Loa Loa (eye worm) glutathione reductase 0.003 0.0039 0.0039
Schistosoma mansoni tar DNA-binding protein 0.007 0.0115 0.0235
Echinococcus multilocularis protein kinase c epsilon type 0.0056 0.0088 0.042
Onchocerca volvulus 0.0023 0.0026 0.004
Entamoeba histolytica protein kinase, putative 0.0011 0.0003 0.0056
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0007 0.0265
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0063 0.0251
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0009 0.0000016117 0.0000076971
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0009 0.0000016117 0.0000076971
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0009 0.0000016117 0.0000033059
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0034 0.0034
Brugia malayi Transient-receptor-potential like protein 0.0023 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0076 0.0156
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0088 0.0149 1
Entamoeba histolytica protein kinase, putative 0.0011 0.0003 0.0056
Echinococcus granulosus microtubule associated protein 2 0.0329 0.0608 0.2903
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0136 0.024 0.024
Entamoeba histolytica p21-activated kinase 0.0011 0.0003 0.0056
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0063 0.0103 0.049
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.0026 0.0124
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.012 0.0211 0.0849
Onchocerca volvulus 0.0072 0.0118 0.018
Echinococcus multilocularis cyclin dependent kinase 0.0013 0.0006 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0063 0.03
Loa Loa (eye worm) RhoGAP domain-containing protein 0.001 0.0001 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0089 0.0151 0.0721
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Leishmania major hypothetical protein, unknown function 0.0023 0.0026 0.0151
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.001 0.0002 0.0116
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0047 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Schistosoma mansoni lipoxygenase 0.0026 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.1905 0.3605 0.3605
Entamoeba histolytica protein kinase, putative 0.0136 0.024 0.5393
Brugia malayi Syntrophin-1 0.001 0.0001 0.0001
Echinococcus multilocularis thioredoxin glutathione reductase 0.003 0.0039 0.0185
Echinococcus granulosus DCC interacting protein 13 beta 0.001 0.0001 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Trichomonas vaginalis sucrase-isomaltase, putative 0.0027 0.0034 0.0034
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0049 0.0076 0.0363
Loa Loa (eye worm) voltage-gated calcium channel 0.0023 0.0026 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Brugia malayi Variant SH3 domain containing protein 0.001 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0074 0.0123 0.0589
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0011 0.0003 0.0015
Giardia lamblia GTOR 0.0014 0.0009 0.0307
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0115 0.0201 0.0808
Echinococcus granulosus sodium channel protein 0.0023 0.0026 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus multilocularis dynamin 1 0.001 0.0001 0.0004
Loa Loa (eye worm) TAR-binding protein 0.007 0.0115 0.0115
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0026 0.1053
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0049 0.0076 0.0076
Echinococcus multilocularis ryanodine receptor 44f 0.111 0.2094 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0063 0.0251
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0023 0.0026 0.0026
Echinococcus multilocularis stromal cell derived factor 2 0.0243 0.0445 0.2124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0007 0.0026
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0026 0.0124
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.002 0.0021 0.002
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0023 0.0026 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0001 0.0001
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1309 0.2473 1
Leishmania major folate/biopterin transporter, putative 0.0011 0.0003 0.0015
Giardia lamblia Fructose-bisphosphate aldolase 0.0139 0.0247 1
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Leishmania major trypanothione reductase 0.003 0.0039 0.0226
Brugia malayi intermediate filament protein 0.003 0.0039 0.0039
Leishmania major DNA damage repair protein, putative 0.0013 0.0007 0.0038
Schistosoma mansoni goodpasture antigen-binding protein 0.001 0.0001 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Loa Loa (eye worm) voltage-gated potassium channel 0.0023 0.0026 0.0026
Schistosoma mansoni rho gtpase activating protein 0.001 0.0001 0.0002
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0023 0.0026 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0007 0.0026
Echinococcus multilocularis serine threonine protein kinase 0.0071 0.0118 0.0563
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0007 0.0026
Echinococcus granulosus myotubularin protein 13 0.0013 0.0006 0.003
Trypanosoma brucei glycosyl hydrolase-like protein 0.001 0.0002 0.0003
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0011 0.0003 0.001
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0023 0.0026 0.0124
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.001 0.0001 0.0057
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0049 0.0076 0.0076
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0026 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0026 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0012 0.0005 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0009 0.0009
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0023 0.0026 0.0026
Loa Loa (eye worm) syntrophin-1 0.001 0.0001 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0026 0.0032 0.0154
Onchocerca volvulus 0.003 0.0039 0.0059
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.001 0.0001 0.0057
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0012 0.0012
Schistosoma mansoni centaurin alpha 0.001 0.0001 0.0002
Brugia malayi cation channel family protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Entamoeba histolytica protein kinase, putative 0.0146 0.0259 0.5815
Toxoplasma gondii hypothetical protein 0.0023 0.0026 0.1053
Echinococcus multilocularis rac serine:threonine kinase 0.0098 0.0168 0.0801
Echinococcus granulosus thioredoxin glutathione reductase 0.003 0.0039 0.0185
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.001 0.0002 0.0008
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1905 0.3605 0.7394
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0039 0.0153
Brugia malayi Cytohesin 3 0.0089 0.0152 0.0152
Loa Loa (eye worm) AGC/AKT protein kinase 0.0146 0.0259 0.0259
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Schistosoma mansoni ryanodine receptor related 0.1553 0.2935 0.6021
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0063 0.0103 0.049
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0016 0.0012 0.0056
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0011 0.0003 0.001
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0419 0.0779 0.1599
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0023 0.0026 0.0124
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0006 0.0124
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0026 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0007 0.0026
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.001 0.0001 0.0004
Schistosoma mansoni dynamin 0.001 0.0001 0.0002
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0023 0.0026 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0034 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0089 0.0151 0.0151
Entamoeba histolytica protein kinase, putative 0.0146 0.0259 0.5815
Leishmania major DNA polymerase eta, putative 0.0013 0.0007 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0009 0.0045
Schistosoma mansoni tyrosine kinase 0.0009 0.0000016117 0.0000033059
Leishmania major protein kinase, putative 0.0011 0.0003 0.0015
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0086 0.0145 0.0693
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.001 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Onchocerca volvulus 0.002 0.0021 0.0031
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0023 0.0027 0.0027
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0000016117 0.0000016117
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0009 0.0000016117 0.0000016117
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0023 0.0026 0.0026
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0012 0.0005 0.0004
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0013 0.0006 0.0033
Echinococcus granulosus pdz domain containing protein 0.001 0.0001 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus multilocularis actin binding protein anillin 0.001 0.0001 0.0004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0026 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis short transient receptor potential channel 6 0.0023 0.0026 0.0124
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0014 0.0009 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0014 0.0009 0.0034
Echinococcus granulosus Pleckstrin y 0.001 0.0001 0.0004
Entamoeba histolytica protein kinase 2, putative 0.0088 0.0149 0.3336
Brugia malayi Glycosyl hydrolases family 31 protein 0.0089 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0115 0.0201 0.0201
Plasmodium falciparum oxysterol-binding protein, putative 0.001 0.0001 0.0057
Loa Loa (eye worm) hypothetical protein 0.0115 0.0201 0.0201
Echinococcus multilocularis microtubule associated protein 2 0.0329 0.0608 0.2903
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0022 0.0025 0.0118
Trichomonas vaginalis glutathione reductase, putative 0.001 0.0002 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0034 0.0754
Schistosoma mansoni two-pore calcium channel 0.0023 0.0026 0.0053
Echinococcus granulosus ryanodine receptor 44f 0.0862 0.1621 0.7741
Loa Loa (eye worm) voltage-dependent calcium channel 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0007 0.0026
Echinococcus multilocularis serine:threonine protein kinase N2 0.0049 0.0076 0.0363
Brugia malayi probable spectrin beta chain 0.001 0.0001 0.0001
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus granulosus Pleckstrin y 0.001 0.0001 0.0004
Brugia malayi phosphoinositide-dependent protein kinase I 0.0016 0.0012 0.0012
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0026 0.1053
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.001 0.0002 0.0016
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0011 0.0003 0.001
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0026 0.0053
Trypanosoma brucei trypanothione reductase 0.003 0.0039 0.0153
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0034 0.0047 0.0047
Brugia malayi Protein kinase c protein 2 0.0026 0.0032 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0006 0.0006
Trichomonas vaginalis protein transport protein sec7, putative 0.0011 0.0003 0.0002
Brugia malayi hypothetical protein 0.0023 0.0026 0.0026
Echinococcus multilocularis transient receptor potential gamma protein 0.0023 0.0026 0.0124
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0026 0.0124
Echinococcus granulosus Oxysterol binding protein 11 0.001 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0026 0.0124
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0023 0.0026 0.004
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0026 0.0124
Entamoeba histolytica PH domain containing protein kinase, putative 0.0011 0.0003 0.0056
Echinococcus granulosus tyrosine protein kinase Lyn 0.0011 0.0003 0.0012
Schistosoma mansoni oxysterol-binding protein 1 0.001 0.0001 0.0002
Schistosoma mansoni nck2/grb4 0.0009 0.0000016117 0.0000033059
Brugia malayi Thioredoxin reductase 0.003 0.0039 0.0039
Brugia malayi RhoGAP domain containing protein 0.001 0.0001 0.0001
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0048 0.0073 0.0073
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0026 0.0124
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0026 0.0124
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0016 0.0012 0.0246
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni syntrophin 0.001 0.0001 0.0002
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0094 0.0161 0.0769
Echinococcus multilocularis Oxysterol binding protein 11 0.001 0.0001 0.0004
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0023 0.0026 0.004
Entamoeba histolytica ARF GTPase activating protein, putative 0.001 0.0001 0.000000019108
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0088 0.0149 0.0599
Echinococcus multilocularis N chimaerin 0.001 0.0001 0.0005
Onchocerca volvulus outspread protein homolog 0.001 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0023 0.0026 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0031 0.0031
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0011 0.0003 0.001
Schistosoma mansoni intermediate filament proteins 0.003 0.0039 0.0079
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Schistosoma mansoni alpha glucosidase 0.0027 0.0034 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0063 0.5569
Brugia malayi cation channel family protein 0.3015 0.5717 0.5717
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0091 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0243 0.0445 0.0912
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0063 0.0062
Trypanosoma cruzi NIMA-related kinase, putative 0.0011 0.0003 0.001
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0011 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0026 0.0124
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.001 0.0002 0.0002
Giardia lamblia DNA damage repair protein 0.0013 0.0007 0.0223
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0006 0.0124
Onchocerca volvulus 0.001 0.0001 0.0001
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0026 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0009 0.0000016117 0.0000016117
Brugia malayi Uncoordinated protein 104 0.001 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Brugia malayi ion channel NompC 0.0023 0.0026 0.0026
Loa Loa (eye worm) phosphatidylinositol 3 0.0057 0.009 0.009
Plasmodium vivax phospholipase C-like, putative 0.0048 0.0073 0.4927
Mycobacterium ulcerans hypothetical protein 0.0013 0.0007 0.0497
Echinococcus granulosus lamin dm0 0.003 0.0039 0.0184
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0023 0.0026 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.001 0.0002 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0032 0.0043 0.0959
Giardia lamblia DINP protein human, muc B family 0.0042 0.0063 0.2493
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0007 0.0483
Loa Loa (eye worm) MIR domain-containing protein 0.0243 0.0445 0.0445
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0023 0.0026 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Trypanosoma brucei cdc2-related kinase 1 0.0013 0.0006 0.0022
Schistosoma mansoni phospholipase C beta 0.002 0.0021 0.0042
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0004 0.002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0088 0.0149 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.001 0.0002 0.0004
Toxoplasma gondii thioredoxin reductase 0.003 0.0039 0.1581
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0056 0.0088 0.0088
Schistosoma mansoni lamin 0.003 0.0039 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Brugia malayi SH2 domain containing protein 0.033 0.0609 0.0609
Echinococcus multilocularis serine:threonine protein kinase N2 0.0049 0.0076 0.0363
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0086 0.0146 0.0699
Echinococcus granulosus geminin 0.0359 0.0666 0.318
Schistosoma mansoni phospholipase C beta 0.0091 0.0154 0.0317
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0034 0.0034
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0009 0.0000016117 0.0000076971
Echinococcus granulosus N chimaerin 0.001 0.0001 0.0005
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0023 0.0026 0.0124
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0115 0.0201 0.1193
Onchocerca volvulus Glucosylceramidase homolog 0.3456 0.6555 1
Schistosoma mansoni zinc finger protein 0.001 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.3642 0.6909 0.6909
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0007 0.0015
Echinococcus multilocularis oxysterol binding protein 1 0.001 0.0001 0.0004
Trypanosoma cruzi Protein kinase B 0.0098 0.0168 0.0675
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.001 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0012 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0063 0.0101 0.0406
Loa Loa (eye worm) hypothetical protein 0.033 0.0609 0.0609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.001 0.0001 0.0002
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0115 0.0115
Echinococcus multilocularis musashi 0.003 0.0039 0.0184
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0012 0.0005 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0076 0.0076
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.001 0.0002 0.0116
Schistosoma mansoni DNA polymerase eta 0.0042 0.0063 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0000016117 0.0000016117
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0063 0.0251
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0068 0.0112 1
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Brugia malayi voltage-dependent calcium channel 0.0023 0.0026 0.0026
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.001 0.0002 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.001 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0095 0.0094
Echinococcus multilocularis potassium large conductance calcium activated 0.0023 0.0026 0.0124
Echinococcus granulosus cytohesin 1 0.0089 0.0152 0.0725
Onchocerca volvulus 0.001 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0048 0.0073 0.0433
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.001 0.0002 0.0003
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0009 0.0000016117 0.0000016117
Trichomonas vaginalis glucosylceramidase, putative 0.3642 0.6909 0.6909
Trypanosoma cruzi NIMA-related kinase, putative 0.0011 0.0003 0.001
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0023 0.0026 0.0124
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0063 0.03
Leishmania major dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0038 0.015
Brugia malayi Pleckstrin Homology Domain 0.0013 0.0006 0.0006
Trypanosoma cruzi DNA polymerase eta, putative 0.0013 0.0007 0.0026
Echinococcus granulosus ryanodine receptor 44f 0.111 0.2094 1
Loa Loa (eye worm) ion channel NompC 0.0023 0.0026 0.0026
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0006 0.003
Echinococcus granulosus nervana 2 0.0086 0.0146 0.0699
Echinococcus granulosus c src tyrosine kinase 0.0009 0.0000016117 0.0000076971
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.001 0.0001 0.0001
Echinococcus granulosus two pore calcium channel protein 2 0.0023 0.0026 0.0124
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.001 0.0001 0.0004
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0049 0.0076 0.0363
Schistosoma mansoni vav2 0.002 0.002 0.0041
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Leishmania major DNA polymerase kappa, putative 0.0042 0.0063 0.0371
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0011 0.0003 0.0105
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0034 0.0047 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0076 0.0156
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0042 0.0063 0.03
Onchocerca volvulus Protein melted homolog 0.001 0.0001 0.0001
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0089 0.0152 0.0312
Plasmodium falciparum thioredoxin reductase 0.003 0.0039 0.2599
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.001 0.0002 0.0003
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.001 0.0001 0.0004
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.1553 0.2935 0.2935
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0012 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Entamoeba histolytica protein kinase, putative 0.0011 0.0003 0.0056
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0026 0.1053
Schistosoma mansoni tyrosine kinase 0.0009 0.0000016117 0.0000033059
Echinococcus granulosus tyrosine protein kinase Src42A 0.0009 0.0000016117 0.0000076971
Schistosoma mansoni alpha-glucosidase 0.0072 0.0118 0.0243
Toxoplasma gondii hypothetical protein 0.0023 0.0026 0.1053
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0038 0.015
Leishmania major acetoin dehydrogenase e3 component-like protein 0.001 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Schistosoma mansoni tyrosine kinase 0.0009 0.0000016117 0.0000033059
Trichomonas vaginalis protein transport protein sec7, putative 0.0011 0.0003 0.0002
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0006 0.0188
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0026 0.0053
Schistosoma mansoni atypical protein kinase C 0.0052 0.0081 0.0167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.001 0.0001 0.0057
Schistosoma mansoni myotubularin-related protein 0.001 0.0001 0.0002
Trichomonas vaginalis mercuric reductase, putative 0.001 0.0002 0.0001
Echinococcus granulosus stromal cell derived factor 2 0.0243 0.0445 0.2124
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0023 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0007 0.0026
Echinococcus multilocularis two pore calcium channel protein 2 0.0023 0.0026 0.0124
Schistosoma mansoni goodpasture antigen-binding protein 0.001 0.0001 0.0002
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0049 0.0076 0.0363
Echinococcus granulosus serine/threonine protein kinase 0.0098 0.0168 0.0801
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.001 0.0001 0.0005
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0023 0.0026 0.0053
Entamoeba histolytica hypothetical protein 0.0011 0.0003 0.0056
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Schistosoma mansoni tyrosine kinase 0.0009 0.0000016117 0.0000033059
Giardia lamblia Kinase, AGC PKA 0.0088 0.0149 0.5999
Brugia malayi GTP-ase activating protein for Arf containing protein 0.001 0.0001 0.0001
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0006 0.0188
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0012 0.0005 0.0091
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0014 0.0009 0.0034
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0063 0.0101 0.0406
Schistosoma mansoni tar DNA-binding protein 0.007 0.0115 0.0235
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0026 0.0124
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Plasmodium vivax glutathione reductase, putative 0.003 0.0039 0.2599
Echinococcus granulosus NCK adaptor protein 0.0009 0.0000016117 0.0000076971
Plasmodium falciparum protein kinase 5 0.0013 0.0006 0.0426
Loa Loa (eye worm) hypothetical protein 0.111 0.2094 0.2094
Entamoeba histolytica hypothetical protein 0.0012 0.0005 0.0097
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0007 0.0026
Brugia malayi Dynamin 0.001 0.0001 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.001 0.0002 0.0116
Schistosoma mansoni transient receptor potential channel 0.0023 0.0026 0.0053
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Brugia malayi polk-prov protein 0.0013 0.0007 0.0007
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0026 0.0053
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0023 0.0026 0.0053
Trypanosoma brucei glucosidase, putative 0.0027 0.0034 0.0136
Entamoeba histolytica PH domain containing protein kinase, putative 0.0011 0.0003 0.0056
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0006 0.0022
Plasmodium vivax conserved Plasmodium protein, unknown function 0.001 0.0001 0.0057
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus granulosus dynamin 1 0.001 0.0001 0.0004
Leishmania major serine/threonine-protein kinase a, putative 0.0011 0.0003 0.0015
Entamoeba histolytica PH domain containing protein kinase, putative 0.0098 0.0168 0.3758
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.001 0.0001 0.0001
Loa Loa (eye worm) AGC/PKN protein kinase 0.0049 0.0076 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Loa Loa (eye worm) RhoGEF domain-containing protein 0.001 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0027 0.0034 0.0747
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0012 0.0011
Echinococcus multilocularis lamin 0.003 0.0039 0.0184
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.001 0.0001 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0007 0.0265
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0026 0.0053
Trichomonas vaginalis maltase-glucoamylase, putative 0.001 0.0002 0.0001
Leishmania major hypothetical protein, conserved 0.089 0.1675 1
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Loa Loa (eye worm) RNA binding protein 0.007 0.0115 0.0115
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0011 0.0003 0.001
Echinococcus multilocularis tar DNA binding protein 0.007 0.0115 0.0548
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0012 0.0005 0.0004
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0026 0.0124
Schistosoma mansoni serine/threonine kinase 0.0049 0.0076 0.0156
Echinococcus multilocularis neutral alpha glucosidase AB 0.0027 0.0034 0.0164
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.002 0.0021 0.0021
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0059 0.0094 0.0559
Schistosoma mansoni transient receptor potential channel 0.0023 0.0026 0.0053
Echinococcus multilocularis cytohesin 1 0.0089 0.0152 0.0725
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0063 0.03
Brugia malayi Protein kinase domain containing protein 0.0016 0.0012 0.0012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0000016117 0.0000076971
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0034 0.0034
Entamoeba histolytica protein kinase, putative 0.0016 0.0012 0.0246
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0023 0.0026 0.0053
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.001 0.0001 0.0004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0063 0.0063
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0023 0.0026 0.0124
Brugia malayi Protein kinase domain containing protein 0.0049 0.0076 0.0076
Loa Loa (eye worm) PH domain-containing protein 0.001 0.0001 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0026 0.0124
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0115 0.0115
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0034 0.0754
Echinococcus granulosus serine:threonine protein kinase N2 0.0049 0.0076 0.0363
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0011 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus granulosus short transient receptor potential channel 6 0.0023 0.0026 0.0124
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0026 0.0053
Echinococcus granulosus short transient receptor potential channel 6 0.0023 0.0026 0.0124
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0012 0.0012
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0063 0.0129
Echinococcus granulosus two pore calcium channel protein 1 0.0023 0.0026 0.0124
Echinococcus granulosus calcium activated potassium channel 0.0024 0.0029 0.0136
Brugia malayi Glycosyl hydrolases family 31 protein 0.001 0.0002 0.0002
Schistosoma mansoni rhogef and pleckstrin domain protein 0.001 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0012 0.0005 0.0016
Plasmodium vivax PH domain containing protein 0.001 0.0001 0.0057
Echinococcus multilocularis Ras associated and pleckstrin y 0.001 0.0001 0.0004
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0017 0.0014 0.0509
Loa Loa (eye worm) uncoordinated protein 104 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0026 0.0026
Echinococcus granulosus intermediate filament protein 0.003 0.0039 0.0184
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0026 0.0053
Leishmania major protein kinase, putative 0.0011 0.0003 0.0015
Brugia malayi Dynamin 0.001 0.0001 0.0001
Schistosoma mansoni lamin 0.003 0.0039 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus granulosus lamin 0.003 0.0039 0.0184
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.001 0.0001 0.0004
Loa Loa (eye worm) voltage-gated potassium channel 0.0023 0.0026 0.0026
Onchocerca volvulus 0.0133 0.0235 0.0359
Loa Loa (eye worm) intermediate filament protein 0.003 0.0039 0.0039
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.002 0.0021 0.008
Echinococcus granulosus calcium dependent secretion activator 1 0.001 0.0001 0.0004
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0063 0.0063
Onchocerca volvulus 0.0243 0.0445 0.0679
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0027 0.0034 0.1399
Echinococcus granulosus transient receptor potential gamma protein 0.0023 0.0026 0.0124
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0012 0.0005 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0026 0.0053
Echinococcus granulosus serine threonine protein kinase nrc 0.0088 0.0149 0.0711
Loa Loa (eye worm) ryanodine receptor 0.0419 0.0779 0.0779
Brugia malayi Variant SH3 domain containing protein 0.0166 0.0299 0.0299
Brugia malayi Sex muscle abnormal protein 5 0.0009 0.0000016117 0.0000016117
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0034 0.0047 0.0047
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0013 0.0006 0.023
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0088 0.0149 0.0711
Leishmania major glycosyl hydrolase-like protein 0.001 0.0002 0.0004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0089 0.0151 0.0721
Brugia malayi SRC-1 0.0009 0.0000016117 0.0000016117
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0063 0.0251
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0094 0.0161 0.0769
Echinococcus multilocularis RNA directed DNA polymerase 0.0019 0.0017 0.0083
Schistosoma mansoni hypothetical protein 0.0359 0.0666 0.1366
Trichomonas vaginalis alpha-glucosidase, putative 0.001 0.0002 0.0001
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0034 0.0047 0.0186
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.001 0.0002 0.5
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0006 0.0022
Echinococcus granulosus cyclin dependent kinase 1 0.0013 0.0006 0.003
Treponema pallidum fructose-bisphosphate aldolase 0.0139 0.0247 1
Brugia malayi olfactory channel protein osm-9 0.0023 0.0026 0.0026
Echinococcus multilocularis serine:threonine protein kinase 38 0.0049 0.0076 0.0363
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0011 0.0003 0.001
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0063
Echinococcus multilocularis calcium dependent secretion activator 1 0.001 0.0001 0.0004
Brugia malayi hypothetical protein 0.001 0.0001 0.0001
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0014 0.0009 0.005
Schistosoma mansoni alpha-glucosidase 0.0072 0.0118 0.0243
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0026 0.0124
Brugia malayi Plekhf2 protein 0.001 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0123 0.0253
Loa Loa (eye worm) rho-GTPase-activating 0.001 0.0001 0.0001
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0023 0.0026 0.0124
Trypanosoma brucei unspecified product 0.0029 0.0038 0.015
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Brugia malayi MIR domain containing protein 0.0243 0.0445 0.0445
Loa Loa (eye worm) hypothetical protein 0.0156 0.0279 0.0279
Echinococcus multilocularis GRB2 associated binding protein 3 0.001 0.0001 0.0004
Echinococcus multilocularis oxysterol binding protein 9 0.001 0.0001 0.0004
Plasmodium falciparum PH domain-containing protein, putative 0.001 0.0001 0.0057
Echinococcus multilocularis dna polymerase eta 0.0042 0.0063 0.03
Brugia malayi RNA binding protein 0.007 0.0115 0.0115
Echinococcus multilocularis Pleckstrin y 0.001 0.0001 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0001 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0026 0.0124
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0013 0.0006 0.003
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0034 0.0047 0.1037
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0011 0.0003 0.001
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1309 0.2473 1
Echinococcus multilocularis DCC interacting protein 13 beta 0.001 0.0001 0.0004
Schistosoma mansoni oxysterol-binding protein 1 0.001 0.0001 0.0002
Plasmodium falciparum glutathione reductase 0.001 0.0002 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Echinococcus granulosus potassium large conductance calcium activated 0.0023 0.0026 0.0124
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.002 0.0021 0.002
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0009 0.0000016117 0.0000076971
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0026 0.0124
Schistosoma mansoni hypothetical protein 0.0079 0.0132 0.027
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.001 0.0001 0.0004
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0011 0.0003 0.001
Brugia malayi Protein kinase domain containing protein 0.0013 0.0006 0.0006
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0001 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0139 0.0247 0.0247
Echinococcus granulosus dna polymerase kappa 0.0042 0.0063 0.03
Echinococcus multilocularis tyrosine protein kinase Abl 0.0009 0.0000016117 0.0000076971
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Schistosoma mansoni tar DNA-binding protein 0.007 0.0115 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0026 0.0032 0.0154
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0063 0.0062
Brugia malayi protein kinase C II. 0.0056 0.0088 0.0088
Schistosoma mansoni tar DNA-binding protein 0.007 0.0115 0.0235
Entamoeba histolytica PH domain containing protein kinase, putative 0.0011 0.0003 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0038 0.015
Schistosoma mansoni voltage-gated ion channel 0.0023 0.0026 0.0053
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0007 0.0265
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Echinococcus granulosus growth factor receptor bound protein 2 0.0009 0.0000016117 0.0000076971
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0024 0.0027 0.0027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.001 0.0002 0.0004
Echinococcus multilocularis geminin 0.0359 0.0666 0.318
Onchocerca volvulus 0.003 0.0039 0.0059
Echinococcus multilocularis conserved hypothetical protein 0.0023 0.0026 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0009 0.0009
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0012 0.0005 0.0025
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0009 0.0000016117 0.0000076971
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0006 0.0006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0063 0.0129
Plasmodium falciparum thioredoxin reductase 0.001 0.0002 0.0116
Echinococcus multilocularis pdz domain containing protein 0.001 0.0001 0.0004
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0015 0.0011 0.0024
Schistosoma mansoni inositol 145-trisphosphate receptor 0.2573 0.4875 1
Onchocerca volvulus 0.001 0.0001 0.0001
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0049 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) Plcb4 protein 0.0091 0.0154 0.0154
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.001 0.0001 0.0004
Echinococcus granulosus RNA directed DNA polymerase 0.0019 0.0017 0.0083
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0023 0.0026 0.0124
Schistosoma mansoni growth factor receptor-bound protein 0.001 0.0001 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.001 0.0002 0.0116
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0014 0.0009 0.019
Echinococcus granulosus expressed conserved protein 0.0079 0.0132 0.0628
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.001 0.0002 0.0037
Loa Loa (eye worm) AGC/NDR protein kinase 0.0049 0.0076 0.0076
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0026 0.0124
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.001 0.0001 0.0004
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0026 0.0124
Toxoplasma gondii protein kinase domain-containing protein 0.0011 0.0003 0.0105
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi TAR-binding protein 0.007 0.0115 0.0115
Plasmodium falciparum glutathione reductase 0.003 0.0039 0.2599
Brugia malayi cell division control protein 2 homolog 0.0013 0.0006 0.0006
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.001 0.0002 0.0005
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.001 0.0002 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus multilocularis short transient receptor potential channel 6 0.0023 0.0026 0.0124
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0034 0.0034
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0086 0.0145 0.0693
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0023 0.0026 0.0102
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0011 0.0003 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0009 0.0000016117 0.0000076971
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0014 0.0009 0.0009
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0023 0.0026 0.0124
Echinococcus multilocularis oxysterol binding protein 3 0.001 0.0001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0063 0.5569
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0026 0.1053
Loa Loa (eye worm) thioredoxin reductase 0.003 0.0039 0.0039
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0023 0.0026 0.0151
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.001 0.0002 0.0004
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0026 0.0124
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0026 0.0124
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0012 0.0005 0.0004
Schistosoma mansoni serine/threonine-protein kinase 0.0098 0.0168 0.0344
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0076 0.0076
Echinococcus granulosus Rho GTPase activating protein 24 0.001 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0053
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0026 0.0124
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0023 0.0026 0.0124
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0026 0.0124
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0026 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0034 0.0034
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.001 0.0001 0.0057
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0026 0.0124
Echinococcus multilocularis c src tyrosine kinase 0.0009 0.0000016117 0.0000076971
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0014 0.0009 0.019
Entamoeba histolytica hypothetical protein 0.0011 0.0003 0.0056
Echinococcus granulosus protein kinase C gamma type 0.0071 0.0118 0.0563
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Schistosoma mansoni transient receptor potential channel 0.0023 0.0026 0.0053
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0034 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.3456 0.6555 0.6555
Trypanosoma cruzi trypanothione reductase, putative 0.001 0.0002 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0009 0.0000016117 0.0000076971
Echinococcus multilocularis lamin dm0 0.003 0.0039 0.0184
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0063 0.0251
Schistosoma mansoni hypothetical protein 0.0359 0.0666 0.1366
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.003 0.0039 0.3366
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.001 0.0001 0.0004
Trichomonas vaginalis mannosyltransferase 1, putative 0.0243 0.0445 0.0444
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0034 0.0047 0.0186
Brugia malayi MAX-1A 0.001 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Echinococcus granulosus tyrosine protein kinase Src64B 0.0009 0.0000016117 0.0000076971
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0076 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.5267 1 1
Echinococcus multilocularis ryanodine receptor 44f 0.0862 0.1621 0.7741
Trypanosoma brucei cdc2-related kinase 3 0.0013 0.0006 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Brugia malayi phospholipase C homolog 0.0031 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0000016117 0.0000033059
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.001 0.0002 0.5
Echinococcus multilocularis voltage dependent calcium channel 0.0023 0.0026 0.0124
Echinococcus granulosus voltage gated hydrogen channel 1 0.0023 0.0026 0.0124
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0026 0.1053
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.001 0.0001 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0098 0.0168 0.0344
Loa Loa (eye worm) hypothetical protein 0.0115 0.0201 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0009 0.0009
Schistosoma mansoni zinc finger protein 0.001 0.0001 0.0002
Schistosoma mansoni voltage-dependent calcium channel 0.0023 0.0026 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0034 0.0136
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0048 0.0073 0.0073
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0023 0.0026 0.0102
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0026 0.0124
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0026 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0004
Echinococcus multilocularis Glutaredoxin protein 5 0.0086 0.0146 0.0699
Brugia malayi Tyrosine-protein kinase abl-1 0.0009 0.0000016117 0.0000016117
Schistosoma mansoni adapter molecule crk 0.0009 0.0000016117 0.0000033059
Onchocerca volvulus 0.0013 0.0006 0.001
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0019 0.0017 0.0083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0006 0.003
Brugia malayi GTP-ase activating protein for Arf containing protein 0.001 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0259 0.0259
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0011 0.0003 0.001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0068 0.0112 1
Brugia malayi Protein kinase domain containing protein 0.0146 0.0259 0.0259
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0166 0.0299 0.0299
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0004 0.0013
Brugia malayi Hr1 repeat family protein 0.0049 0.0076 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0023 0.0026 0.0026
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0014 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.001 0.0002 0.0001
Loa Loa (eye worm) cytohesin 3 0.0089 0.0152 0.0152
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0009 0.0000016117 0.0000076971
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0011 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0094 0.0161 0.0161
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0007 0.0026
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.008 0.0133 0.5536
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0029 0.0038 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Echinococcus granulosus Pleckstrin y 0.001 0.0001 0.0004
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0023 0.0026 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Onchocerca volvulus 0.0105 0.0182 0.0278
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Echinococcus multilocularis two pore calcium channel protein 1 0.0023 0.0026 0.0124
Echinococcus multilocularis Pleckstrin y 0.001 0.0001 0.0004
Echinococcus granulosus neutral alpha glucosidase AB 0.0027 0.0034 0.0164
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.001 0.0001 0.0001
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0013 0.0006 0.0006
Echinococcus multilocularis calcium activated potassium channel 0.0024 0.0029 0.0136
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.5267 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0009 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0039 0.0039
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0063 0.0103 0.021
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0026 0.0124
Loa Loa (eye worm) SRC-1 0.0009 0.0000016117 0.0000016117
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0139 0.0247 0.5548
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Plasmodium vivax thioredoxin reductase, putative 0.003 0.0039 0.2599
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Echinococcus multilocularis NCK adaptor protein 0.0009 0.0000016117 0.0000076971
Echinococcus multilocularis myotubularin protein 13 0.0013 0.0006 0.003
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0012 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Echinococcus multilocularis pleckstrin y domain containing family A 0.001 0.0001 0.0004
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0007 0.0483
Brugia malayi Protein kinase domain containing protein 0.0049 0.0076 0.0076
Echinococcus granulosus NDR protein kinase 0.0049 0.0076 0.0363
Onchocerca volvulus 0.001 0.0001 0.0001
Echinococcus granulosus protein kinase c iota type 0.0052 0.0081 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0088 0.018
Schistosoma mansoni dynamin 0.001 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0006 0.0006
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0027 0.0034 0.0747
Echinococcus multilocularis beta 1 syntrophin 0.001 0.0001 0.0004
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0016 0.0012 0.0056
Onchocerca volvulus Putative zinc finger protein 0.001 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0023 0.0026 0.0026
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0023 0.0026 0.0026
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.2153 0.4078 0.4078
Schistosoma mansoni transient receptor potential channel 4 0.0023 0.0026 0.0053
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0026 0.0124
Onchocerca volvulus 0.0062 0.01 0.0153
Entamoeba histolytica PH domain containing protein kinase, putative 0.0098 0.0168 0.3758
Echinococcus granulosus sodium leak channel non selective protein 0.0023 0.0026 0.0124
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0049 0.0076 0.0363
Loa Loa (eye worm) ryanodine receptor 0.0023 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.001 0.0002 0.0004
Echinococcus granulosus cyclin dependent kinase 5 0.0013 0.0006 0.003
Echinococcus multilocularis Pleckstrin y 0.001 0.0001 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0012 0.0005 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Trypanosoma brucei chrX additional, unordered contigs 0.0013 0.0007 0.0026
Schistosoma mansoni vesicular amine transporter 0.0023 0.0026 0.0053
Echinococcus granulosus TRP transient receptor potential channel 0.0023 0.0026 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0123 0.0253
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0139 0.0247 0.5548
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Entamoeba histolytica PH domain containing protein kinase, putative 0.0011 0.0003 0.0056
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0098 0.0168 0.0675
Loa Loa (eye worm) phosphatidylinositol 3 0.0014 0.0009 0.0009
Echinococcus multilocularis cyclin dependent kinase 5 0.0013 0.0006 0.003
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0049 0.0076 0.0363
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0034 0.0034
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0063 0.0371
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0009 0.0000016117 0.0000076971
Echinococcus multilocularis protein kinase c iota type 0.0052 0.0081 0.0389
Echinococcus granulosus shaker cognate 0.0023 0.0026 0.0124
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0063 0.0102 0.0208
Brugia malayi TBC domain containing protein 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.2125 0.4023 0.4023
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0023 0.0026 0.0026
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0026 0.0124
Loa Loa (eye worm) hypothetical protein 0.0062 0.01 0.01
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.001 0.0001 0.0004
Brugia malayi Cadps2 protein 0.001 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0011 0.0003 0.0225
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus GRB2 associated binding protein 3 0.001 0.0001 0.0004
Echinococcus granulosus hypothetical protein 0.0023 0.0026 0.0124
Trichomonas vaginalis alpha-glucosidase, putative 0.001 0.0002 0.0001
Echinococcus granulosus oxysterol binding protein 3 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0063 0.0251
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Schistosoma mansoni 60S ribosomal protein L21 0.0023 0.0026 0.0053
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0014 0.0009 0.005
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0011 0.0003 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0003 0.0003
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0026 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0006 0.0013
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0115 0.0201 0.0808
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0027 0.0034 0.0034
Trypanosoma brucei protein kinase, putative 0.0011 0.0003 0.001
Brugia malayi PH domain containing protein 0.001 0.0001 0.0001
Schistosoma mansoni microtubule-associated protein tau 0.0329 0.0608 0.1247
Brugia malayi Oxysterol-binding protein 0.001 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0063 0.5569
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0007 0.0026
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Trichomonas vaginalis alpha-glucosidase, putative 0.001 0.0002 0.0001
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0000016117 0.0000033059
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0039 0.0039
Echinococcus multilocularis nervana 2 0.0086 0.0146 0.0699
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Echinococcus multilocularis growth factor receptor bound protein 2 0.0009 0.0000016117 0.0000076971
Echinococcus multilocularis Rho GTPase activating protein 24 0.001 0.0001 0.0004
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0026 0.0124
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0014 0.0009 0.0044
Loa Loa (eye worm) calcium channel 0.0023 0.0026 0.0026
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0024 0.0027 0.0027
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0006 0.0022
Leishmania major alpha glucosidase II subunit, putative 0.0027 0.0034 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0076 0.0156
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0007 0.0026
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.001 0.0001 0.0004
Brugia malayi glutathione reductase 0.003 0.0039 0.0039
Echinococcus granulosus Pleckstrin domain containing protein family B 0.001 0.0001 0.0004
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0091 0.0154 0.0154
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.001 0.0002 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.001 0.0002 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0003 0.0002
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0086 0.0146 0.0699
Trypanosoma brucei unspecified product 0.0042 0.0063 0.0251
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0023 0.0026 0.0124
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0093 0.0159 0.0327
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0063 0.1398
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0023 0.0026 0.0026
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0011 0.0003 0.001
Echinococcus multilocularis nervana 2 0.0086 0.0146 0.0699
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0006 0.0013
Leishmania major DNA polymerase eta, putative 0.0042 0.0063 0.0371
Entamoeba histolytica protein kinase, putative 0.0049 0.0076 0.1692
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0014 0.0009 0.0019
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0012 0.0012
Echinococcus granulosus tar DNA binding protein 0.007 0.0115 0.0548
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0048 0.0073 0.4927
Entamoeba histolytica MIR domain protein 0.0243 0.0445 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus nervana 2 0.0086 0.0146 0.0699
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0023 0.0026 0.0124
Echinococcus granulosus beta 1 syntrophin 0.001 0.0001 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0026 0.0053
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0088 0.0149 0.0711
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0076 0.0156
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0026 0.0053
Echinococcus granulosus oxysterol binding protein 1 0.001 0.0001 0.0004
Leishmania major DNA polymerase kappa, putative 0.0013 0.0007 0.0038
Entamoeba histolytica protein kinase, putative 0.0011 0.0003 0.0056
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0014 0.0009 0.0034
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0022 0.0025 0.0118
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0049 0.0076 0.0363

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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