Detailed information for compound 214187

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 264.726 | Formula: C11H19ClNO4-
  • H donors: 2 H acceptors: 4 LogP: 0.33 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(=O)O.CCCC(N(CC#C)C)C.[Cl-]
  • InChi: 1S/C9H17N.C2H2O4.ClH/c1-5-7-9(3)10(4)8-6-2;3-1(4)2(5)6;/h2,9H,5,7-8H2,1,3-4H3;(H,3,4)(H,5,6);1H/p-1
  • InChiKey: UMQUDFCEPLKPGE-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0052 0.0218 0.0855
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0128 0.0642 0.2525
Echinococcus multilocularis neuroligin 0.0022 0.0055 0.0122
Echinococcus multilocularis serotonin receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus neuropeptide receptor 0.0013 0.0005 0.0011
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0174 0.0898 0.3519
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.019 0.0286
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus multilocularis protoporphyrinogen oxidase 0.0143 0.0724 0.1611
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0639 0.0847
Loa Loa (eye worm) hypothetical protein 0.0183 0.0945 0.3716
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0043 0.0167
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0043 0.0167 0.0658
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0059 0.0132
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0009 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0013 0.0005 0.0019
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0043 0.0167 0.0372
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1217 0.5278
Giardia lamblia Aspartyl-tRNA synthetase 0.0014 0.0011 0.0099
Echinococcus multilocularis neuropeptide FF receptor 2 0.0013 0.0005 0.0011
Echinococcus multilocularis glycyl tRNA synthetase 0.0024 0.0064 0.0143
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0044 0.0174
Mycobacterium ulcerans hypothetical protein 0.0021 0.0049 0.0059
Echinococcus granulosus importin subunit beta 1 0.0029 0.0089 0.0199
Echinococcus granulosus dnaJ subfamily B 0.0823 0.4494 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Echinococcus granulosus General substrate transporter 0.0367 0.1969 0.4382
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0102 0.0228
Loa Loa (eye worm) hypothetical protein 0.0095 0.046 0.1809
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0066 0.0299 0.1542
Echinococcus multilocularis G protein coupled receptor 139 0.0013 0.0005 0.0011
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Trypanosoma brucei sugar transporter, putative 0.006 0.0264 0.1361
Echinococcus granulosus lysine specific histone demethylase 1A 0.0143 0.0724 0.1611
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0005 0.0019
Schistosoma mansoni glucose transport protein 0.0428 0.2303 0.5124
Brugia malayi GnHR receptor homolog 0.0013 0.0005 0.0019
Brugia malayi beta-lactamase family protein 0.0041 0.0158 0.0622
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0094 0.0368
Brugia malayi hypothetical protein 0.006 0.0264 0.1039
Plasmodium falciparum protoporphyrinogen oxidase 0.0143 0.0724 0.0724
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0058 0.0229
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0158 0.0352
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0013 0.0005 0.0011
Plasmodium falciparum glutathione reductase 0.0038 0.0143 0.0143
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.1472
Schistosoma mansoni amine GPCR 0.0013 0.0005 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0043 0.0167
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0736 0.2895
Onchocerca volvulus Cell death protein 3 homolog 0.0067 0.0304 0.1178
Trypanosoma brucei metacaspase MCA3 0.002 0.0043 0.0202
Echinococcus granulosus allatostatin A receptor 0.0013 0.0005 0.0011
Schistosoma mansoni glucose transport protein 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0104 0.0509 0.2001
Chlamydia trachomatis glutamine binding protein 0.0018 0.0033 0.0405
Echinococcus granulosus carboxylesterase 5A 0.0132 0.0663 0.1476
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0158 0.023
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0013 0.0005 0.0011
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0013 0.0005 0.0019
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0005 0.0011
Trypanosoma cruzi ISWI complex protein 0.0019 0.0034 0.0156
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0374 0.0833
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0011 0.0011
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0043 0.0167 0.0372
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.008 0.0374 0.5141
Trichomonas vaginalis sugar transporter, putative 0.0133 0.0666 0.2881
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0158 0.0352
Loa Loa (eye worm) hypothetical protein 0.0421 0.2266 0.8907
Onchocerca volvulus 0.006 0.0264 0.1022
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0299 0.0665
Echinococcus multilocularis BC026374 protein (S09 family) 0.0022 0.0055 0.0122
Echinococcus granulosus mitogen activated protein kinase 0.0066 0.0299 0.0665
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0043 0.0096
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0218 0.0484
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Plasmodium falciparum lysine--tRNA ligase 0.0095 0.046 0.046
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0056
Echinococcus granulosus apoptotic protease activating factor 1 0.0047 0.0192 0.0427
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0414 0.0612
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0132 0.066 0.0656
Mycobacterium ulcerans sugar transporter 0.006 0.0264 0.0347
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0158 0.0669
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.013 0.0511
Schistosoma mansoni ran 0.0021 0.0047 0.0106
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis calcium dependent protein kinase 0.0123 0.0612 0.1362
Echinococcus multilocularis geminin 0.0336 0.1793 0.3991
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni neuropeptide receptor 0.0013 0.0005 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.0157
Schistosoma mansoni myst-related protein 0.0013 0.0002 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0004 0.0004
Brugia malayi hypothetical protein 0.002 0.004 0.0157
Toxoplasma gondii glycyl-tRNA synthetase 0.0024 0.0064 0.0097
Trypanosoma cruzi metacaspase, putative 0.002 0.0043 0.0202
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0158 0.0154
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0043 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Schistosoma mansoni myst-related protein 0.0013 0.0002 0.0004
Echinococcus multilocularis serotonin transporter 0.0471 0.2544 0.5661
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0358 0.1915 0.753
Echinococcus granulosus orexin receptor type 2 0.0013 0.0005 0.0011
Brugia malayi putative neuropeptide receptor NPR1 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0666 0.2881
Plasmodium falciparum calcium-dependent protein kinase 4 0.0132 0.066 0.066
Onchocerca volvulus 0.008 0.0374 0.1456
Echinococcus granulosus neuropeptide receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0128 0.0642 0.2525
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0005 0.0011
Plasmodium vivax glycine--tRNA ligase, putative 0.0024 0.0064 0.006
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Echinococcus granulosus lysine specific histone demethylase 1A 0.0143 0.0724 0.1611
Schistosoma mansoni opsin-like receptor 0.0013 0.0005 0.0011
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0023
Brugia malayi N-terminal motif family protein 0.0174 0.0898 0.3531
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.008 0.0374 0.0833
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0428 0.2303 0.5124
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0011 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0374 0.0833
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0014 0.0009 0.0025
Mycobacterium ulcerans monoamine oxidase 0.0143 0.0724 0.0961
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0005 0.0011
Brugia malayi Bromodomain containing protein 0.005 0.021 0.0824
Trypanosoma brucei metacaspase 0.002 0.0043 0.0202
Leishmania major threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0336
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0374 0.0833
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0047 0.0186
Chlamydia trachomatis proline--tRNA ligase 0.0045 0.0182 0.2471
Trypanosoma cruzi UDP-galactopyranose mutase 0.0143 0.0724 0.3766
Entamoeba histolytica hypothetical protein 0.0095 0.046 0.6964
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0005 0.0011
Onchocerca volvulus 0.0232 0.1217 0.4775
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0014 0.0011 0.0009
Plasmodium vivax lysine--tRNA ligase, putative 0.0095 0.046 0.0456
Plasmodium falciparum calcium-dependent protein kinase 3 0.0132 0.066 0.066
Treponema pallidum sodium- and chloride- dependent transporter 0.0471 0.2544 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.076 0.3969
Schistosoma mansoni sugar transporter 0.006 0.0264 0.0588
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0374 0.0833
Brugia malayi Melatonin receptor type 1A 0.0013 0.0005 0.0019
Echinococcus multilocularis para nitrobenzyl esterase 0.0022 0.0055 0.0122
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0222 0.0873
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0314
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0005 0.0011
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0131 0.066 0.1469
Brugia malayi RE15519p 0.0013 0.0005 0.0019
Brugia malayi hypothetical protein 0.008 0.0374 0.1472
Leishmania major importin beta-1 subunit, putative 0.0023 0.0059 0.031
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0143 0.0724 1
Echinococcus granulosus sex peptide receptor 0.0013 0.0005 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0158 0.0805
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0014 0.0011 0.0029
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0059 0.0132
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0374 0.0833
Trichomonas vaginalis glucose transporter, putative 0.006 0.0264 0.1131
Schistosoma mansoni sodium-dependent amino acid transporter 0.008 0.0374 0.0833
Plasmodium vivax importin-beta 2, putative 0.0029 0.0089 0.0085
Plasmodium vivax histidine--tRNA ligase, putative 0.0014 0.0011 0.0007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.0639 0.1421
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0043 0.0065
Loa Loa (eye worm) beta-lactamase 0.0041 0.0158 0.0622
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.006 0.0264 0.0388
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0192 0.0754
Loa Loa (eye worm) sugar transporter 0.0428 0.2303 0.9052
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0095 0.046 0.2386
Brugia malayi glutathione reductase 0.0038 0.0143 0.0562
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1364 0.7497 1
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0023
Schistosoma mansoni intermediate filament proteins 0.0029 0.0094 0.0208
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0132
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.008 0.0374 0.0833
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0167 0.0658
Onchocerca volvulus 0.0043 0.0167 0.064
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0024 0.0064 0.2307
Loa Loa (eye worm) hypothetical protein 0.0029 0.0091 0.0356
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0132 0.066 0.0995
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0004 0.0023
Onchocerca volvulus 0.006 0.0264 0.1022
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0158 0.0669
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Schistosoma mansoni gliotactin 0.0022 0.0055 0.0122
Trypanosoma cruzi hexose transporter, putative 0.0133 0.0666 0.3464
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.002 0.004 0.0157
Echinococcus multilocularis lamin dm0 0.0029 0.0094 0.0208
Schistosoma mansoni ap endonuclease 0.002 0.0044 0.0099
Brugia malayi major facilitator superfamily protein 0.006 0.0264 0.1039
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.0058 0.0229
Schistosoma mansoni opsin-like receptor 0.0013 0.0005 0.0011
Schistosoma mansoni glucose transport protein 0.0428 0.2303 0.5124
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0158 0.0622
Brugia malayi glycyl-tRNA synthetase 0.0024 0.0064 0.0253
Brugia malayi Serotonin receptor 0.0013 0.0005 0.0019
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Brugia malayi neuropeptide F receptor 0.0013 0.0005 0.0019
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0043 0.0167 0.0372
Plasmodium falciparum hexose transporter 0.0428 0.2303 0.2303
Brugia malayi Carboxylesterase family protein 0.0022 0.0055 0.0215
Plasmodium falciparum calcium-dependent protein kinase 2 0.0132 0.066 0.066
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0043 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0049 0.0066
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.1472
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0044 0.006
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0058 0.0229
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0734 0.1632
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Toxoplasma gondii sugar transporter ST3 0.006 0.0264 0.0398
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Chlamydia trachomatis threonine--tRNA ligase 0.0024 0.0064 0.0833
Brugia malayi Serotonin receptor 0.0013 0.0005 0.0019
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0081 0.0382 0.0851
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0011 0.0035
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0471 0.2544 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.0157
Schistosoma mansoni neuropeptide receptor 0.0013 0.0005 0.0011
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Onchocerca volvulus 0.008 0.0374 0.1456
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0014 0.0011 0.0244
Schistosoma mansoni biogenic amine receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0043 0.0167 0.0372
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0158 0.023
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.007 0.0276
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0044 0.0044
Echinococcus granulosus Sugar transporter ERD6 protein 0.006 0.0264 0.0588
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0047 0.0047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0044 0.0628
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0005 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0299 0.1282
Brugia malayi hypothetical protein 0.002 0.004 0.0157
Echinococcus multilocularis apoptotic protease activating factor 1 0.0047 0.0192 0.0427
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0736 0.2895
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0024 0.0064 0.0143
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0059 0.0132
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.006 0.0264 1
Echinococcus granulosus cpg binding protein 0.0096 0.0466 0.1036
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0374 0.0833
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.0374 0.0833
Echinococcus granulosus 7tm_1 domain containing protein 0.0013 0.0005 0.0011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0047 0.0106
Echinococcus multilocularis dro:myosuppressin receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis g-protein coupled receptor 0.0013 0.0005 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0639 0.1421
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0044 0.0232
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0158 0.0205
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0468 0.0693
Echinococcus granulosus hypothetical protein 0.0013 0.0005 0.0011
Echinococcus multilocularis somatostatin receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0013 0.0005 0.0019
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0143 0.0562
Schistosoma mansoni hypothetical protein 0.0305 0.1622 0.3609
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0044 0.021
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.006 0.0264 0.0347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0044 0.0174
Brugia malayi Importin beta-1 subunit 0.0029 0.0089 0.0351
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.0423 0.0941
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0055 0.0122
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0025
Brugia malayi G-protein coupled receptor 0.0013 0.0005 0.0019
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0014 0.0011 0.0042
Schistosoma mansoni lamin 0.0029 0.0094 0.0208
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0253
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0158 0.0669
Treponema pallidum glycyl-tRNA synthetase 0.0014 0.0011 0.0026
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0051
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0358 0.1915 0.753
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0059 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.006 0.0264 0.0264
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0066 0.0299 0.0451
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Toxoplasma gondii histone lysine-specific demethylase 0.0143 0.0724 0.1091
Schistosoma mansoni protein kinase 0.0131 0.066 0.1469
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0005 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0736 0.1639
Schistosoma mansoni amine oxidase 0.0143 0.0724 0.1611
Echinococcus multilocularis sex peptide receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Toxoplasma gondii sugar transporter ST1 0.006 0.0264 0.0398
Toxoplasma gondii hypothetical protein 0.008 0.0374 0.0564
Brugia malayi Cation transporter family protein 0.0043 0.0167 0.0658
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0023 0.0091
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0011 0.0006
Schistosoma mansoni hypothetical protein 0.0019 0.0034 0.0076
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0314
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Brugia malayi neuropeptide F receptor 0.0013 0.0005 0.0019
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0051
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Loa Loa (eye worm) LGC-31 protein 0.0043 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Giardia lamblia Hexose transporter 0.006 0.0264 0.4075
Echinococcus granulosus histidyl tRNA synthetase 0.0014 0.0011 0.0024
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0143 0.0724 0.1611
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0043 0.0167 0.0658
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0081 0.038 0.4911
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0024 0.0064 0.0314
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0131 0.066 0.2595
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0736 0.1639
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.015 0.076 0.3956
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0044 0.0644
Onchocerca volvulus 0.0029 0.0094 0.035
Brugia malayi Carboxylesterase family protein 0.0022 0.0055 0.0215
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.1472
Plasmodium falciparum thioredoxin reductase 0.0038 0.0143 0.0143
Loa Loa (eye worm) TYRA-2 protein 0.0013 0.0005 0.0019
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0639 0.0847
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Schistosoma mansoni sodium/chloride dependent transporter 0.0471 0.2544 0.5661
Plasmodium vivax glutathione reductase, putative 0.0038 0.0143 0.0139
Trypanosoma cruzi metacaspase, putative 0.002 0.0043 0.0202
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0143 0.0724 0.0724
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.004 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Brugia malayi Cation transporter family protein 0.0043 0.0167 0.0658
Trypanosoma brucei histidyl-tRNA synthetase 0.0014 0.0011 0.0035
Toxoplasma gondii lysine-tRNA ligase 0.0095 0.046 0.0694
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0471 0.2544 0.5661
Leishmania major glucose transporter/membrane transporter D2, putative 0.0133 0.0666 0.3479
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Schistosoma mansoni adenoreceptor 0.0013 0.0005 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0005 0.0011
Onchocerca volvulus 0.006 0.0264 0.1022
Brugia malayi beta-lactamase 0.0041 0.0158 0.0622
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0095 0.046 0.0608
Loa Loa (eye worm) hypothetical protein 0.0132 0.0663 0.2607
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0264 0.1039
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0043 0.0167 0.0372
Schistosoma mansoni glutamate receptor NMDA 0.0061 0.0268 0.0597
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0013 0.0005 0.0011
Schistosoma mansoni zinc finger protein 0.0033 0.0111 0.0248
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0414 0.0612
Schistosoma mansoni sugar transporter 0.006 0.0264 0.0588
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0014 0.0011 0.0137
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0044 0.0099
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0073 0.0164
Schistosoma mansoni amine GPCR 0.0013 0.0005 0.0011
Entamoeba histolytica protein kinase, putative 0.0131 0.066 1
Echinococcus multilocularis GPCR, family 2 0.0017 0.0023 0.0051
Entamoeba histolytica hypothetical protein 0.0023 0.0059 0.0871
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0049 0.0233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Echinococcus multilocularis caspase 2 0.0067 0.0304 0.0676
Brugia malayi Pre-SET motif family protein 0.0204 0.1062 0.4177
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0374 0.0833
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.008 0.0374 0.0833
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.076 0.3956
Leishmania major UDP-galactopyranose mutase 0.0143 0.0724 0.378
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Treponema pallidum prolyl-tRNA synthetase 0.0045 0.0182 0.07
Loa Loa (eye worm) carboxylesterase 0.0022 0.0055 0.0215
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0013 0.0005 0.0011
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0143 0.0724 0.072
Schistosoma mansoni biogenic amine receptor 0.0013 0.0005 0.0011
Schistosoma mansoni amine GPCR 0.0013 0.0005 0.0011
Trichomonas vaginalis esterase, putative 0.0041 0.0158 0.0669
Echinococcus granulosus glutamate NMDA receptor subunit 0.0061 0.0268 0.0597
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0005 0.0019
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0736 0.1639
Brugia malayi sulfakinin receptor protein 0.0013 0.0005 0.0019
Schistosoma mansoni acetylcholine receptor-related 0.002 0.004 0.0089
Giardia lamblia Threonyl-tRNA synthetase 0.0024 0.0064 0.094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0047 0.0226
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.0639 0.3334
Onchocerca volvulus 0.006 0.0264 0.1022
Trypanosoma brucei metacaspase 5, putative 0.002 0.0043 0.0202
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0724 0.072
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Schistosoma mansoni lamin 0.0029 0.0094 0.0208
Onchocerca volvulus 0.0043 0.0167 0.064
Brugia malayi hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Brugia malayi Cell death protein 3 precursor 0.0067 0.0304 0.1195
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0153 0.0153
Toxoplasma gondii exonuclease III APE 0.002 0.0044 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Plasmodium falciparum aspartate--tRNA ligase 0.0014 0.0011 0.0011
Brugia malayi putative neuropeptide receptor 0.0013 0.0005 0.0019
Onchocerca volvulus 0.0022 0.0055 0.0196
Trypanosoma cruzi UDP-galactopyranose mutase 0.0143 0.0724 0.3766
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0043 0.0202
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0049 0.0233
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0018 0.0033 0.0039
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0011 0.0024
Echinococcus multilocularis allatostatin A receptor 0.0013 0.0005 0.0011
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0014 0.0011 0.0008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0081 0.0382 0.0851
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0095 0.046 0.6093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0056
Onchocerca volvulus 0.006 0.0264 0.1022
Schistosoma mansoni hypothetical protein 0.0047 0.0192 0.0427
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0024 0.0064 0.0253
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0374 0.0833
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0051
Chlamydia trachomatis aspartate--tRNA(Asp/Asn) ligase 0.0014 0.0011 0.0088
Plasmodium falciparum amino acid transporter, putative 0.008 0.0374 0.0374
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) acetylcholinesterase 1 0.0132 0.0663 0.2607
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0374 0.0833
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0143 0.0724 0.1611
Schistosoma mansoni hypothetical protein 0.0336 0.1793 0.3991
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0013 0.0005 0.0011
Trypanosoma cruzi ISWI complex protein 0.0019 0.0034 0.0156
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Trypanosoma brucei glucose transporter 1E 0.0133 0.0666 0.3464
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Plasmodium vivax threonine--tRNA ligase, putative 0.0024 0.0064 0.006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0262 0.1383 0.2058
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Echinococcus granulosus serotonin receptor 0.0013 0.0005 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Schistosoma mansoni bromodomain containing protein 0.0086 0.0406 0.0904
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Schistosoma mansoni neuropeptide f receptor 76f 0.0013 0.0005 0.0011
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0167 0.0372
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Loa Loa (eye worm) 63kd antigen 0.0014 0.0011 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0425 0.1669
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0158 0.0805
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.1472
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0053 0.0223 0.0876
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0014 0.0011 0.0024
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0045 0.0182 0.0237
Toxoplasma gondii thioredoxin reductase 0.0038 0.0143 0.0215
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.004 0.0157
Echinococcus granulosus calcium dependent protein kinase 0.0123 0.0612 0.1362
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0043 0.0167 0.0658
Echinococcus multilocularis lamin 0.0029 0.0094 0.0208
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0014 0.0011 0.0132
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0005 0.0011
Brugia malayi hypothetical protein 0.002 0.004 0.0157
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis acetylcholinesterase 0.0132 0.0663 0.1476
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Trypanosoma cruzi metacaspase, putative 0.002 0.0043 0.0202
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.0666 0.3464
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0128 0.0642 0.2776
Trypanosoma cruzi hexose transporter, putative 0.0133 0.0666 0.3464
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0143 0.0724 0.0724
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0047 0.0226
Schistosoma mansoni acetylcholine receptor subunit beta 0.002 0.004 0.0089
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.004 0.0089
Brugia malayi hypothetical protein 0.006 0.0264 0.1039
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.002 0.004 0.0089
Echinococcus granulosus alpha 1A adrenergic receptor 0.0013 0.0005 0.0011
Brugia malayi Pre-SET motif family protein 0.0031 0.0102 0.0403
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0053 0.0226 0.0889
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0685 0.2691
Brugia malayi amine oxidase, flavin-containing family protein 0.0143 0.0724 0.2847
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Plasmodium falciparum metacaspase-like protein 0.002 0.0043 0.0043
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus granulosus peptide allatostatin:somatostatin 0.0013 0.0005 0.0011
Onchocerca volvulus 0.0041 0.0158 0.0604
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0014 0.0011 0.0017
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0089
Echinococcus multilocularis solute carrier family 22 0.006 0.0264 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0044 0.0174
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0066 0.0299 0.1561
Leishmania major histidyl-tRNA synthetase, putative 0.0014 0.0011 0.0057
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0024 0.0064 0.0947
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0143 0.0139
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.015 0.076 0.1146
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0008 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0044 0.0173 0.0386
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0059 0.0239
Brugia malayi Sugar transporter family protein 0.006 0.0264 0.1039
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni neurotransmitter gated ion channel 0.0023 0.0058 0.013
Echinococcus granulosus caspase 2 0.0067 0.0304 0.0676
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0143 0.0725
Echinococcus multilocularis 0.0143 0.0724 0.1611
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0061 0.0268 0.0597
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.019 0.0807
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0167 0.0372
Plasmodium vivax hypothetical protein, conserved 0.008 0.0374 0.037
Schistosoma mansoni bromodomain containing protein 0.0014 0.0008 0.0018
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.0564
Loa Loa (eye worm) hypothetical protein 0.0132 0.0663 0.2607
Loa Loa (eye worm) histone methyltransferase 0.0029 0.009 0.0352
Trichomonas vaginalis sugar transporter, putative 0.0133 0.0666 0.2881
Plasmodium falciparum mitogen-activated protein kinase 2 0.0691 0.3766 0.3766
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis orexin receptor type 2 0.0013 0.0005 0.0011
Leishmania major asparaginyl-tRNA synthetase, putative 0.0014 0.0011 0.0056
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0009 0.0021
Leishmania major trypanothione reductase 0.0038 0.0143 0.0746
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0018 0.0033 0.0115
Loa Loa (eye worm) acetylcholine receptor protein 0.002 0.004 0.0157
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Plasmodium falciparum calcium-dependent protein kinase 5 0.0132 0.066 0.066
Trypanosoma cruzi hexose transporter, putative 0.006 0.0264 0.1361
Trichomonas vaginalis glucose transporter, putative 0.0133 0.0666 0.2881
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Schistosoma mansoni cpg binding protein 0.0089 0.0425 0.0945
Schistosoma mansoni hypothetical protein 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Brugia malayi major facilitator superfamily protein 0.006 0.0264 0.1039
Loa Loa (eye worm) hypothetical protein 0.0053 0.0222 0.0873
Brugia malayi Carboxylesterase family protein 0.0132 0.0663 0.2607
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0158 0.0622
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0153 0.2302
Echinococcus multilocularis neuropeptide s receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0044 0.0174
Loa Loa (eye worm) carboxylesterase 0.0022 0.0055 0.0215
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0013 0.0005 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0299 0.1282
Mycobacterium tuberculosis Carboxylesterase LipT 0.0022 0.0055 0.0075
Loa Loa (eye worm) sugar transporter 0.006 0.0264 0.1039
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0158 0.023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0084 0.0395 0.17
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0051
Plasmodium vivax metacaspase 1, putative 0.002 0.0043 0.0039
Plasmodium falciparum threonine--tRNA ligase 0.0024 0.0064 0.0064
Brugia malayi excitatory GABA receptor EXP-1A 0.0043 0.0167 0.0658
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0167 0.0372
Schistosoma mansoni glucose transporter 0.006 0.0264 0.0588
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0947
Onchocerca volvulus 0.006 0.0264 0.1022
Plasmodium vivax CDK-related protein kinase 6, putative 0.1815 1 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0691 0.3766 0.3764
Entamoeba histolytica protein kinase, putative 0.0131 0.066 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0013 0.0005 0.0019
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0051
Echinococcus granulosus mitogen activated protein kinase 3 0.0066 0.0299 0.0665
Schistosoma mansoni cpg binding protein 0.0096 0.0466 0.1036
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0095 0.046 0.0608
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni threonyl-tRNA synthetase 0.0014 0.0011 0.0024
Echinococcus multilocularis cpg binding protein 0.0096 0.0466 0.1036
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0066 0.0299 0.1561
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0023 0.0058 0.0229
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0044 0.1541
Leishmania major metacaspase, putative 0.002 0.0043 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0043 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Trypanosoma cruzi glucose transporter, putative 0.006 0.0264 0.1361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Brugia malayi Carboxylesterase family protein 0.0132 0.0663 0.2607
Schistosoma mansoni BC026374 protein (S09 family) 0.0022 0.0055 0.0122
Echinococcus multilocularis zinc finger protein 0.0033 0.0111 0.0248
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0044 0.021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0032
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.1472
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0091
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0132 0.066 0.0995
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0005 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.009 0.0199
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0014 0.0011 0.0028
Plasmodium vivax SET domain protein, putative 0.0031 0.0102 0.0098
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.007 0.0276
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0128 0.0642 0.2525
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.0564
Onchocerca volvulus 0.002 0.004 0.0138
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0736 0.1639
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0128 0.0642 0.879
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0158 0.0669
Plasmodium falciparum calcium-dependent protein kinase 1 0.0132 0.066 0.066
Onchocerca volvulus Putative nachr subunit 0.0043 0.0167 0.064
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0005 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0158 0.162
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0013 0.0005 0.0019
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0059 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) acetyltransferase 0.0152 0.0773 0.3037
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.019 0.0422
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0051
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0468 0.0693
Onchocerca volvulus 0.0022 0.0055 0.0196
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.0511
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0004 0.0023
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus granulosus Threonyl tRNA synthetase C 0.0024 0.0064 0.0143
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Onchocerca volvulus 0.0031 0.0102 0.0384
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0043 0.0167 0.0372
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.006 0.0264 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Leishmania major protein kinase, putative 0.0131 0.066 0.3446
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0022 0.0055 0.0075
Onchocerca volvulus 0.006 0.0264 0.1022
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0047 0.0186
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0622
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0146 0.0324
Mycobacterium ulcerans lipase LipD 0.0041 0.0158 0.0205
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0444
Echinococcus multilocularis solute carrier family 22 0.006 0.0264 0.0588
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0143 0.0724 0.072
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0055 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.066 0.2853
Onchocerca volvulus 0.008 0.0374 0.1456
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0013 0.0005 0.0011
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1364 0.7497 1
Echinococcus multilocularis General substrate transporter 0.0367 0.1969 0.4382
Echinococcus granulosus geminin 0.0336 0.1793 0.3991
Trichomonas vaginalis ran, putative 0.0021 0.0047 0.0188
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0025 0.007 0.0156
Brugia malayi Cam kinase protein 1 0.0131 0.066 0.2595
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0095 0.046 0.1984
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0167 0.0658
Loa Loa (eye worm) follicle stimulating hormone receptor 0.025 0.1315 0.5171
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0374 0.0833
Mycobacterium tuberculosis Possible oxidoreductase 0.0143 0.0724 0.1074
Echinococcus granulosus nAChR subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.0908 0.1369
Loa Loa (eye worm) solute carrier family 6 member 4 0.0471 0.2544 1
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0014 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0089
Giardia lamblia Kinase, CMGC MAPK 0.0066 0.0299 0.4618
Leishmania major glucose transporter, lmgt2 0.0133 0.0666 0.3479
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0018 0.0071
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0261
Onchocerca volvulus 0.0089 0.0425 0.1653
Plasmodium falciparum histidine--tRNA ligase, putative 0.0014 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0468 0.0693
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0059 0.0239
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0044 0.0053
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0043 0.0167 0.0372
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0374 0.0564
Leishmania major hypothetical protein, conserved 0.0021 0.0049 0.0255
Leishmania major C-8 sterol isomerase-like protein 0.0358 0.1915 1
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0724 0.072
Schistosoma mansoni hypothetical protein 0.0823 0.4494 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Toxoplasma gondii ABC1 family protein 0.0041 0.0158 0.0238
Echinococcus granulosus g protein coupled receptor 0.0013 0.0005 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0023 0.0091
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0444
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0153 0.2338
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0037
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.0046 0.0102
Schistosoma mansoni glycyl-tRNA synthetase 0.0024 0.0064 0.0143
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0158 0.0205
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Schistosoma mansoni hypothetical protein 0.0336 0.1793 0.3991
Schistosoma mansoni lysyl-tRNA synthetase 0.0095 0.046 0.1024
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.004 0.0089
Echinococcus granulosus BC026374 protein S09 family 0.0022 0.0055 0.0122
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0024 0.0064 0.023
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0132 0.066 0.0656
Trypanosoma brucei trypanothione reductase 0.0038 0.0143 0.0725
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0023 0.0091
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0055 0.0122
Mycobacterium tuberculosis Probable reductase 0.0087 0.0414 0.0612
Mycobacterium ulcerans hypothetical protein 0.0041 0.0158 0.0205
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.002 0.004 0.0089
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus granulosus neuropeptide s receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis mitogen activated protein kinase 0.0066 0.0299 0.0665
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0024 0.0064 0.0253
Onchocerca volvulus 0.0023 0.0058 0.0211
Chlamydia trachomatis lysine--tRNA ligase 0.0095 0.046 0.6334
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.015 0.076 0.3956
Plasmodium falciparum glutathione reductase 0.0013 0.0004 0.0004
Leishmania major lysyl-tRNA synthetase, putative 0.0095 0.046 0.2403
Echinococcus multilocularis acetylcholinesterase 0.0132 0.0663 0.1476
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0468 0.6213
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0011 0.0006
Brugia malayi hypothetical protein 0.0022 0.0055 0.0215
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0047 0.0043
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0102 0.0154
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0218 0.0484
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.0639 0.0963
Schistosoma mansoni protein kinase 0.0131 0.066 0.1469
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni neuropeptide receptor 0.0013 0.0005 0.0011
Brugia malayi CXXC zinc finger family protein 0.0089 0.0425 0.1669
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0005 0.0011
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0043 0.0167 0.0658
Schistosoma mansoni hypothetical protein 0.0036 0.013 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0666 0.2881
Brugia malayi Carboxylesterase family protein 0.0022 0.0055 0.0215
Echinococcus multilocularis Sugar transporter ERD6 protein 0.006 0.0264 0.0588
Loa Loa (eye worm) GABA receptor subunit 0.0023 0.0058 0.0229
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus GPCR family 2 0.0017 0.0023 0.0051
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0132 0.0663 0.1476
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.019 0.0807
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0024 0.0064 0.008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0005 0.0011
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.0046 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0264 0.1131
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0013 0.0005 0.0019
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0167 0.0372
Echinococcus granulosus nAChR subunit 0.0023 0.0058 0.013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Onchocerca volvulus 0.0043 0.0167 0.064
Brugia malayi lysyl-tRNA synthetase 0.0095 0.046 0.1809
Brugia malayi intermediate filament protein 0.0029 0.0094 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0024 0.0064 0.0253
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0022 0.0055 0.0122
Brugia malayi larval opioid receptor 0.0013 0.0005 0.0019
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0043 0.0065
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.0167 0.0658
Plasmodium falciparum importin beta, putative 0.0029 0.0089 0.0089
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Brugia malayi Tachykinin-like peptides receptor 99D 0.0013 0.0005 0.0019
Trypanosoma cruzi metacaspase, putative 0.002 0.0043 0.0202
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0131 0.066 0.3431
Entamoeba histolytica hypothetical protein 0.0023 0.0058 0.0855
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0013 0.0005 0.0019
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0044 0.021
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0146 0.0324
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0018 0.0071
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0047 0.0676
Leishmania major GTP-binding protein, putative 0.0021 0.0047 0.0248
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0222 0.0873
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.01 0.0395
Brugia malayi beta-lactamase family protein 0.0041 0.0158 0.0622
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0066 0.0299 0.1542
Brugia malayi PHD-finger family protein 0.0039 0.0147 0.0579
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0414 0.0612
Onchocerca volvulus 0.002 0.004 0.0138
Onchocerca volvulus 0.0043 0.0167 0.064
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0018 0.0033 0.0405
Echinococcus granulosus para nitrobenzyl esterase 0.0022 0.0055 0.0122
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Leishmania major hypothetical protein, conserved 0.0041 0.0158 0.0826
Mycobacterium tuberculosis Conserved protein 0.0041 0.0158 0.023
Schistosoma mansoni importin beta-1 0.0029 0.0089 0.0199
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0043 0.0167 0.0372
Schistosoma mansoni myosin xvIII 0.0013 0.0005 0.0011
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) hypothetical protein 0.0471 0.2544 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0128 0.0642 0.143
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0043 0.0096
Loa Loa (eye worm) hypothetical protein 0.0174 0.0898 0.3531
Echinococcus granulosus glycyl tRNA synthetase 0.0024 0.0064 0.0143
Schistosoma mansoni ran 0.0021 0.0047 0.0106
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0011 0.0024
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0414 0.0612
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0218 0.0484
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0049 0.0233
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0061 0.0267 0.105
Giardia lamblia Glycyl-tRNA synthetase 0.0024 0.0064 0.094
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0013 0.0005 0.0019
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0013 0.0005 0.0011
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0143 0.0724 0.0961
Treponema pallidum asparaginyl-tRNA synthetase 0.0014 0.0011 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0374 0.0833
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.019 0.0185
Echinococcus granulosus g protein coupled receptor 0.0013 0.0005 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0143 0.0724 0.1074
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0094 0.0368
Echinococcus multilocularis serotonin receptor 0.0013 0.0005 0.0011
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.0639 0.0947
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0005 0.0011
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0014 0.0011 0.0029
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0058 0.013
Onchocerca volvulus 0.0047 0.0192 0.0737
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0005 0.0011
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0024 0.0064 0.0097
Echinococcus multilocularis musashi 0.0029 0.0094 0.0208
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Schistosoma mansoni growth hormone secretagogue receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0043 0.0167 0.0372
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0004 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0072 0.0333 0.1719
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Plasmodium vivax proline--tRNA ligase, putative 0.015 0.076 0.0756
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.002 0.004 0.0157
Loa Loa (eye worm) hypothetical protein 0.0086 0.0408 0.1605
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0047 0.0106
Trypanosoma cruzi hexose transporter 0.0133 0.0666 0.3464
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0128 0.0642 0.143
Onchocerca volvulus 0.0043 0.0167 0.064
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.004 0.0089
Echinococcus multilocularis synaptic vesicle 2 protein 0.006 0.0264 0.0588
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0167 0.0372
Trypanosoma brucei glucose transporter 2A 0.0133 0.0666 0.3464
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0013 0.0005 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Echinococcus granulosus dro:myosuppressin receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0066 0.0299 0.1175
Schistosoma mansoni caspase-7 (C14 family) 0.0067 0.0304 0.0676
Toxoplasma gondii protein kinase, putative 0.1209 0.6635 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0169
Giardia lamblia Prolyl-tRNA synthetase 0.0128 0.0642 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0033 0.0111 0.0247
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.076 0.3969
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0005 0.0011
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0167 0.0372
Echinococcus granulosus snurportin 1 0.0305 0.1622 0.3609
Echinococcus granulosus solute carrier family 22 0.006 0.0264 0.0588
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0024 0.0064 0.008
Trichomonas vaginalis sugar transporter, putative 0.0133 0.0666 0.2881
Onchocerca volvulus 0.0022 0.0055 0.0196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0014 0.0011 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0102 0.0228
Plasmodium vivax hexose transporter 0.0428 0.2303 0.2299
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0131 0.066 0.2595
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Onchocerca volvulus 0.006 0.0264 0.1022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0005 0.0011
Toxoplasma gondii transporter, major facilitator family protein 0.006 0.0264 0.0398
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0011 0.0011
Brugia malayi G-protein coupled receptor 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Mycobacterium leprae Probable lipase LipE 0.0041 0.0158 0.162
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0158 0.023
Brugia malayi Aspartyl-tRNA synthetase 0.0014 0.0011 0.0042
Onchocerca volvulus 0.0041 0.0158 0.0604
Leishmania major hypothetical protein, conserved 0.006 0.0264 0.138
Echinococcus granulosus neuropeptide receptor A26 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0691 0.3766 0.5677
Brugia malayi hypothetical protein 0.0143 0.0724 0.2847
Onchocerca volvulus 0.0029 0.0094 0.035
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0073 0.0164
Echinococcus granulosus caspase 0.002 0.0043 0.0096
Giardia lamblia Asparaginyl-tRNA synthetase 0.0014 0.0011 0.0099
Echinococcus multilocularis solute carrier family 22 0.006 0.0264 0.0588
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0043 0.0169
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0005 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0049 0.0193
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0158 0.0352
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0264 0.1039
Schistosoma mansoni ap endonuclease 0.002 0.0044 0.0099
Loa Loa (eye worm) melatonin receptor type 1A 0.0013 0.0005 0.0019
Schistosoma mansoni amine GPCR 0.0013 0.0005 0.0011
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1622 0.6375
Plasmodium falciparum transporter, putative 0.008 0.0374 0.0374
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Toxoplasma gondii hypothetical protein 0.008 0.0374 0.0564
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Mycobacterium tuberculosis Conserved protein 0.0041 0.0158 0.023
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0043 0.0096
Trichomonas vaginalis spcc417.12 protein, putative 0.0022 0.0055 0.0219
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0264 0.1039
Trypanosoma brucei protein kinase, putative 0.0066 0.0299 0.1542
Mycobacterium tuberculosis Conserved protein 0.0041 0.0158 0.023
Schistosoma mansoni zinc finger protein 0.0019 0.0034 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0264 0.1131
Schistosoma mansoni protein kinase 0.0131 0.066 0.1469
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Mycobacterium ulcerans oxidoreductase 0.0143 0.0724 0.0961
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) hypothetical protein 0.0047 0.019 0.0746
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Brugia malayi G protein-coupled receptor 0.0013 0.0005 0.0019
Onchocerca volvulus 0.006 0.0264 0.1022
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0167 0.0372
Plasmodium falciparum metacaspase 1 0.002 0.0043 0.0043
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0158 0.0352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0736 0.1639
Echinococcus granulosus neuropeptide FF receptor 2 0.0013 0.0005 0.0011
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0047 0.0071
Brugia malayi Sugar transporter family protein 0.0428 0.2303 0.9052
Trypanosoma brucei metacaspase MCA2 0.002 0.0043 0.0202
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0011 0.0033
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Schistosoma mansoni cpg binding protein 0.0096 0.0466 0.1036
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0005 0.0011
Toxoplasma gondii facilitative glucose transporter GT1 0.0428 0.2303 0.3471
Echinococcus multilocularis G-protein coupled receptor, putative 0.0013 0.0005 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0685 0.2691
Chlamydia trachomatis histidine--tRNA ligase 0.0014 0.0011 0.0093
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.0157
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Chlamydia trachomatis protoporphyrinogen oxidase 0.0143 0.0724 1
Leishmania major lysyl-tRNA synthetase, putative 0.0014 0.0011 0.0056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1062 0.4177
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Echinococcus granulosus G protein coupled receptor 139 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0011 0.0024
Brugia malayi hypothetical protein 0.002 0.004 0.0157
Loa Loa (eye worm) hypothetical protein 0.008 0.0374 0.1472
Plasmodium falciparum thioredoxin reductase 0.0013 0.0004 0.0004
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0043 0.0167 0.0658
Brugia malayi follicle stimulating hormone receptor 0.025 0.1315 0.5171
Brugia malayi Sugar transporter family protein 0.006 0.0264 0.1039
Toxoplasma gondii sugar transporter ST2 0.006 0.0264 0.0398
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus synaptic vesicle 2 protein 0.006 0.0264 0.0588
Echinococcus multilocularis caspase 8 0.002 0.0043 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0168
Schistosoma mansoni sugar transporter 0.006 0.0264 0.0588
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0047 0.0226
Echinococcus granulosus 7TM GPCR rhodopsin 0.0013 0.0005 0.0011
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.004 0.0157
Trichomonas vaginalis sugar transport protein, putative 0.006 0.0264 0.1131
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0128 0.0642 0.2525
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0013 0.0005 0.0011
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0095 0.046 0.2386
Brugia malayi MAP kinase sur-1 0.0066 0.0299 0.1175
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0024 0.0064 0.0314
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0043 0.0167 0.0372
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0471 0.2544 1
Schistosoma mansoni histamine h1 receptor 0.0013 0.0005 0.0011
Leishmania major hypothetical protein, conserved 0.0021 0.0049 0.0255
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.008 0.0374 0.0833
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Echinococcus multilocularis dnaJ subfamily B 0.0823 0.4494 1
Loa Loa (eye worm) hypothetical protein 0.0471 0.2544 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0264 0.1039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Leishmania major glycyl tRNA synthetase, putative 0.0014 0.0011 0.0057
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0021 0.0049 0.0073
Brugia malayi Dopamine receptor 0.0013 0.0005 0.0019
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0044 0.0173 0.0386
Onchocerca volvulus 0.0043 0.0167 0.064
Echinococcus multilocularis nAChR subunit 0.0043 0.0167 0.0372
Echinococcus granulosus solute carrier family 22 0.006 0.0264 0.0588
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0167 0.0658
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0264 0.1039
Treponema pallidum aspartyl-tRNA synthetase 0.0014 0.0011 0.0025
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0081 0.038 0.0561
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0066 0.0299 0.1542
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus acetylcholinesterase 0.0132 0.0663 0.1476
Echinococcus granulosus fmrfamide receptor 0.0013 0.0005 0.0011
Trypanosoma cruzi sugar transporter, putative 0.006 0.0264 0.1361
Loa Loa (eye worm) norepinephrine transporter 0.0471 0.2544 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0081 0.038 0.0561
Loa Loa (eye worm) serotonin transporter b 0.0471 0.2544 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Brugia malayi Cation transporter family protein 0.0043 0.0167 0.0658
Giardia lamblia Lysyl-tRNA synthetase 0.0095 0.046 0.7145
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0018 0.0033 0.0044
Brugia malayi Carboxylesterase family protein 0.0022 0.0055 0.0215
Plasmodium vivax calcium-dependent protein kinase, putative 0.0132 0.066 0.0656
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Onchocerca volvulus 0.0022 0.0055 0.0196
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Leishmania major hypothetical protein, conserved 0.0019 0.0034 0.0178
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0143 0.0724 0.1611
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus granulosus lysyl tRNA synthetase 0.0095 0.046 0.1024
Schistosoma mansoni alpha-1 adrenergic receptor 0.0013 0.0005 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0158 0.0669
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0043 0.0202
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2303 0.5124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0029 0.0094 0.0368
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0005 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1469
Toxoplasma gondii anticodon binding domain-containing protein 0.0014 0.0011 0.0017
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.009 0.0199
Brugia malayi MH2 domain containing protein 0.0136 0.0685 0.2691
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0046 0.0102
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0167 0.0372
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Onchocerca volvulus Putative transporter 0.006 0.0264 0.1022
Loa Loa (eye worm) glutathione reductase 0.0038 0.0143 0.0562
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0167 0.0658
Plasmodium vivax sugar transporter, putative 0.006 0.0264 0.026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Onchocerca volvulus 0.006 0.0264 0.1022
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.002 0.004 0.0157
Echinococcus multilocularis neuropeptide receptor A26 0.0013 0.0005 0.0011
Echinococcus multilocularis lysyl tRNA synthetase 0.0095 0.046 0.1024
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0011
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0128 0.0642 0.143
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.006 0.0264 0.1361
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Plasmodium falciparum glycine--tRNA ligase 0.0014 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Brugia malayi ORL1-like opioid receptor 0.0013 0.0005 0.0019
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0264 0.1039
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0044 0.0158
Schistosoma mansoni neuroligin 3 (S09 family) 0.0022 0.0055 0.0122
Trichomonas vaginalis myo-inositol transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0005 0.0011
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Onchocerca volvulus 0.0023 0.0058 0.0211
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.008 0.0374 0.0833
Echinococcus granulosus g-protein coupled receptor 0.0013 0.0005 0.0011
Brugia malayi Dopamine receptor protein 1 0.0421 0.2266 0.8907
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0033 0.0111 0.0247
Brugia malayi hypothetical protein 0.0047 0.0192 0.0754
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0148 0.0754 0.1137
Echinococcus granulosus lamin 0.0029 0.0094 0.0208
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Schistosoma mansoni nAChR subunit 0.0043 0.0167 0.0372
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0043 0.0167 0.0372
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Treponema pallidum threonyl-tRNA synthetase 0.0024 0.0064 0.0236
Trypanosoma brucei ISWI complex protein 0.0019 0.0034 0.0156
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0094 0.0368
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Plasmodium vivax amine transporter, putative 0.008 0.0374 0.037
Brugia malayi SWIRM domain containing protein 0.0143 0.0724 0.2847
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0167 0.0372
Giardia lamblia Sugar-proton symporter 0.006 0.0264 0.4075
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0167 0.0372
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.0666 0.3464
Schistosoma mansoni amine oxidase 0.0143 0.0724 0.1611
Echinococcus multilocularis nAChR subunit 0.0023 0.0058 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0023 0.0058 0.013
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0089 0.0199
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Echinococcus multilocularis caspase 0.002 0.0043 0.0096
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.006 0.0264 0.0588
Toxoplasma gondii aspartate-tRNA ligase 0.0014 0.0011 0.0016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Loa Loa (eye worm) hypothetical protein 0.0143 0.0724 0.2847
Onchocerca volvulus 0.0143 0.0724 0.2833
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Leishmania major glucose transporter, lmgt1 0.0133 0.0666 0.3479
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0043 0.0167 0.0372
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.019 0.0286
Loa Loa (eye worm) hypothetical protein 0.0067 0.0304 0.1195
Mycobacterium ulcerans integral membrane transport protein 0.006 0.0264 0.0347
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0005 0.0011
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0005 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0158 0.0805
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0018 0.0033 0.0115
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0014 0.0011 0.0043
Echinococcus granulosus zinc finger protein 0.0033 0.0111 0.0248
Trichomonas vaginalis helicase, putative 0.002 0.0043 0.0167
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0143 0.0207
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0043 0.0167 0.0658
Onchocerca volvulus 0.0041 0.0158 0.0604
Echinococcus granulosus caspase 8 0.002 0.0043 0.0096
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0005 0.0011
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0773 0.1719
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0005 0.0011
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0014 0.0011 0.0042
Schistosoma mansoni acetylcholinesterase 0.0022 0.0055 0.0122
Brugia malayi Dopamine receptor protein 2 0.0013 0.0005 0.0019
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0374 0.0833
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0131 0.066 0.2595
Schistosoma mansoni sugar transporter 0.006 0.0264 0.0588
Leishmania major myo-inositol/proton symporter (MIT) 0.006 0.0264 0.138
Loa Loa (eye worm) hypothetical protein 0.0131 0.066 0.2595
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.006 0.0264 0.0388
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0043 0.0167 0.0658
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0005 0.0011
Echinococcus granulosus solute carrier family 22 0.006 0.0264 0.0588
Plasmodium falciparum protein kinase 7 0.1209 0.6635 0.6635
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0005 0.0011
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0022 0.0055 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0736 0.1639
Plasmodium vivax aspartate--tRNA ligase, putative 0.0014 0.0011 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.0351
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0043 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0046 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0049 0.0193
Echinococcus granulosus g protein coupled receptor 0.0013 0.0005 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0222 0.0873
Schistosoma mansoni neuropeptide receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis snurportin 1 0.0305 0.1622 0.3609
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0428 0.2303 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0264 0.1131
Trypanosoma brucei Metacaspase-4 0.002 0.0043 0.0202
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0089 0.0135
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0004 0.0017
Schistosoma mansoni opsin-like receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0059 0.0132
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0299 0.1282
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0044 0.004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0158 0.023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0049 0.0233
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.0666 0.3464
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0022 0.0055 0.0219
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0005 0.0011
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0167 0.0658
Schistosoma mansoni lysyl-tRNA synthetase 0.0095 0.046 0.1024
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0024 0.0064 0.009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0773 0.3037
Echinococcus granulosus tachykinin peptides receptor 99D 0.0013 0.0005 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0005 0.0019
Brugia malayi AKH receptor 0.0013 0.0005 0.0019
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1221 0.6704 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0358 0.1915 1
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0049 0.0233
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0043 0.0167 0.0658
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0022 0.0055 0.0122
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0004 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0299 0.1282
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0167 0.0658
Echinococcus granulosus fetal alzheimer antigen falz 0.0033 0.0111 0.0247
Trypanosoma cruzi histidyl-tRNA synthetase 0.0014 0.0011 0.0035
Mycobacterium ulcerans beta-lactamase 0.0041 0.0158 0.0205
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0013 0.0005 0.0011
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0066 0.0299 0.1542
Echinococcus multilocularis histidyl tRNA synthetase 0.0014 0.0011 0.0024
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0013 0.0005 0.0011
Brugia malayi RNA, U transporter 1 0.0081 0.0381 0.1499
Echinococcus multilocularis solute carrier family 22 0.006 0.0264 0.0588
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0414 0.5414
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0024 0.0064 0.2307
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0773 0.1719
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0374 0.0833
Trichomonas vaginalis glucose transporter, putative 0.0133 0.0666 0.2881
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0013 0.0005 0.0011
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0639 0.0847
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0639 0.1421
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Leishmania major glucose transporter, lmgt3 0.0133 0.0666 0.3479
Plasmodium vivax hypothetical protein, conserved 0.002 0.0043 0.0039
Echinococcus granulosus intermediate filament protein 0.0029 0.0094 0.0208
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0066 0.0299 0.1542
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0102 0.0228
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0013 0.0005 0.0011
Echinococcus granulosus lamin dm0 0.0029 0.0094 0.0208
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0043 0.0168
Plasmodium falciparum proline--tRNA ligase 0.015 0.076 0.076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0005 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0026 0.0073 0.0164
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0218 0.0484
Brugia malayi Bromodomain containing protein 0.01 0.0485 0.1909
Echinococcus granulosus acetylcholinesterase 0.0132 0.0663 0.1476
Echinococcus granulosus serotonin transporter 0.0471 0.2544 0.5661
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0374 0.0833
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0157
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0132 0.066 0.0995
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.008 0.0374 0.1472
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.0639 0.1421
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0264 0.1131
Onchocerca volvulus 0.0471 0.2544 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0043 0.0167 0.0658
Brugia malayi hypothetical protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0019
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0158 0.023
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0013 0.0005 0.0011
Echinococcus granulosus somatostatin receptor 0.0013 0.0005 0.0011
Schistosoma mansoni amine GPCR 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0049 0.0193
Mycobacterium ulcerans dehydrogenase 0.0143 0.0724 0.0961
Echinococcus granulosus neuroligin 0.0022 0.0055 0.0122
Echinococcus multilocularis carboxylesterase 5A 0.0132 0.0663 0.1476
Trypanosoma cruzi hexose transporter, putative 0.0133 0.0666 0.3464
Mycobacterium ulcerans carboxylesterase, LipT 0.0022 0.0055 0.0067
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0011 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.066 0.1469
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0158 0.023
Trypanosoma brucei C-8 sterol isomerase, putative 0.0358 0.1915 1
Brugia malayi hypothetical protein 0.002 0.004 0.0157
Onchocerca volvulus 0.0022 0.0055 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0264 0.1131
Trypanosoma brucei glucose transporter, putative 0.0133 0.0666 0.3464
Echinococcus granulosus solute carrier family 22 0.006 0.0264 0.0588
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0005 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0086 0.0191
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0128 0.0642 0.143
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0014 0.0011 0.0257
Plasmodium falciparum zinc finger protein, putative 0.0013 0.0002 0.0002
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0128 0.0642 0.9732
Entamoeba histolytica Ran family GTPase 0.0021 0.0047 0.069
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0043 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0167 0.0658
Schistosoma mansoni mixed-lineage leukemia protein mll 0.019 0.0984 0.219
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0011
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0059 0.0288
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0736 0.1639
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0014 0.0011 0.0024
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.002 0.004 0.0089
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0167 0.0372
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0132 0.066 0.0656
Onchocerca volvulus 0.002 0.004 0.0138
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0024 0.0064 0.0253
Brugia malayi Thioredoxin reductase 0.0038 0.0143 0.0562
Schistosoma mansoni biogenic amine receptor 0.0013 0.0005 0.0011
Echinococcus multilocularis mitogen activated protein kinase 3 0.0066 0.0299 0.0665
Loa Loa (eye worm) carboxylesterase 0.0132 0.0663 0.2607
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0043 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0005 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0414 0.0612
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0215
Trichomonas vaginalis sugar transporter, putative 0.006 0.0264 0.1131
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0043 0.0167 0.0658

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 5.2 uM kg-1 MAO activity of the compound evaluated in dissected forebrain of rat after 2 hr of administration ChEMBL. 1433183
IC50 (binding) = 0.00000018 M Inhibition of Monoamine oxidase B of rat liver mitochondrial membranes ChEMBL. 1433183
IC50 (binding) = 0.0000056 M Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M ChEMBL. 1433183
IC50 (binding) = 0.000012 M Inhibition of Monoamine oxidase A of rat liver mitochondrial membranes ChEMBL. 1433183
ID50 (functional) = 1.7 uM kg-1 MAO activities in the mouse brain after intraperitoneal administration of compound towards PE (1.9 x 10e-5 M) substrate ChEMBL. 1433183
ID50 (functional) = 113.9 uM kg-1 MAO activities in the mouse brain after intraperitoneal administration of compound towards 5-HT (5 x 10e-4 M) substrate ChEMBL. 1433183
Ratio (binding) = 12.3 Relative affinity for MAO-B of mouse forebrain (ID50) and rat liver (IC50) ChEMBL. 1433183
Ratio (binding) = 67 Ratio of IC50 against mouse brain MAO-A and MAO-B ChEMBL. 1433183
Ratio (binding) = 69 Relative affinity for MAO-A and MAO-B of rat liver. ChEMBL. 1433183
Relative activity (functional) = 18 % Compound was evaluated for MAO-B activity after 21 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 19 % Compound was evaluated for MAO-B activity after 10 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 31 % MAO activities in the mouse brain after oral administration of compound towards PE (1.9 x 10e-5 M) substrate ChEMBL. 1433183
Relative activity (functional) = 31 % Compound was evaluated for MAO-A activity after 21 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 35 % Compound was evaluated for MAO-B activity after 13 days of chronic peritoneal administration in mouse fore brain at dose of 0.25 mg/kg ChEMBL. 1433183
Relative activity (functional) = 40 % Compound was evaluated for MAO-B activity after 1 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 49 % Compound was evaluated for MAO-A activity after 10 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 89 % MAO activities in the mouse brain after oral administration of compound towards 5-HT (5 x 10e-4 M) substrate ChEMBL. 1433183
Relative activity (functional) = 89 % Compound was evaluated for MAO-A activity after 13 days of chronic peritoneal administration in mouse fore brain at dose of 0.25 mg/kg ChEMBL. 1433183
Relative activity (functional) = 91 % Compound was evaluated for MAO-A activity after 1 days of chronic peritoneal administration in mouse fore brain at dose of 2 mg/kg ChEMBL. 1433183
Relative activity (functional) = 94 % Compound was evaluated for MAO-B activity after 1 day of chronic peritoneal administration in mouse fore brain at dose of 0.25 mg/kg ChEMBL. 1433183
Relative activity (functional) = 102 % Compound was evaluated for MAO-A activity after 1 day of chronic peritoneal administration in mouse fore brain at dose of 0.25 mg/kg ChEMBL. 1433183

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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