Detailed information for compound 36667

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 250.337 | Formula: C14H22N2O2
  • H donors: 1 H acceptors: 1 LogP: 2.56 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)CCCCCN(c1ccccc1)N
  • InChi: 1S/C14H22N2O2/c1-2-18-14(17)11-7-4-8-12-16(15)13-9-5-3-6-10-13/h3,5-6,9-10H,2,4,7-8,11-12,15H2,1H3
  • InChiKey: QGYGHMDWNJGIBT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0023 0.0639
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0023 0.0698
Echinococcus granulosus biogenic amine 5HT receptor 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0124 0.0358 0.0357
Brugia malayi Protein kinase domain containing protein 0.0029 0.0048 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.1022 0.3275 0.3274
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Schistosoma mansoni myosin xvIII 0.0124 0.0358 0.0357
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0015 0.1151
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0334 0.1038 0.1038
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0029 0.0912
Plasmodium falciparum glutathione reductase 0.0047 0.0106 0.0631
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi Melatonin receptor type 1A 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0023 0.0639
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0124 0.0358 0.0357
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0023 0.0022
Schistosoma mansoni opsin-like receptor 0.0124 0.0358 0.0357
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0024 0.0158
Schistosoma mansoni inositol monophosphatase 0.0109 0.031 0.0309
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0151 0.015
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0007 0.0035
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0023 0.0698
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0034
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0019 0.0018
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.03 0.8857
Loa Loa (eye worm) hypothetical protein 0.0052 0.0124 0.0123
Loa Loa (eye worm) CYP4Cod1 0.003 0.0051 0.005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0023 0.0639
Loa Loa (eye worm) hypothetical protein 0.0765 0.2441 0.2441
Brugia malayi excitatory GABA receptor EXP-1A 0.0021 0.0023 0.0022
Schistosoma mansoni sodium/chloride dependent transporter 0.3091 1 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0525 0.1661 0.166
Loa Loa (eye worm) hypothetical protein 0.006 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus granulosus bloom syndrome protein 0.0021 0.0023 0.0022
Echinococcus granulosus cGMP dependent protein kinase 0.0015 0.0003 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0015 0.0014
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0007 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0023 0.0639
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.0046 0.0046
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0022 0.0024 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0109 0.031 0.2095
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0023 0.0022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0007 0.0039
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0186
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0124 0.0358 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0019 0.0018
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0032 0.0057 0.0056
Brugia malayi hypothetical protein 0.006 0.0151 0.015
Onchocerca volvulus 0.0124 0.0358 0.0357
Loa Loa (eye worm) TYRA-2 protein 0.0124 0.0358 0.0357
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Echinococcus granulosus tm gpcr rhodopsin 0.0124 0.0358 0.0357
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1022 0.3275 0.3274
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Plasmodium falciparum LCCL domain-containing protein 0.006 0.0151 0.0902
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0151 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0053 0.0354
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0023 0.0145
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0051 0.1606
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Schistosoma mansoni hypothetical protein 0.0051 0.012 0.0119
Schistosoma mansoni thyroid hormone receptor 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0094 0.0262 0.0261
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0019 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Schistosoma mansoni amine GPCR 0.0124 0.0358 0.0357
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0021 0.0023 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0019 0.0018
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0021 0.0023 0.0022
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0023 0.0698
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0019 0.0018
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0106 0.0635
Onchocerca volvulus Putative nachr subunit 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus multilocularis sex peptide receptor 0.0124 0.0358 0.0357
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0501
Brugia malayi Uncoordinated protein 44 0.0028 0.0046 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0019 0.0018
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0005 0.0004
Onchocerca volvulus 0.0124 0.0358 0.0357
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0019 0.0018
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0023 0.0088
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0007 0.0186
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0051 0.005
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0003 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0023 0.0639
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0024 0.0024
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0361 0.1129 0.1128
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0023 0.0639
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0047 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0019 0.0018
Echinococcus granulosus voltage gated potassium channel 0.0032 0.0057 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0019 0.0018
Echinococcus granulosus Ankyrin 0.0029 0.0047 0.0046
Plasmodium falciparum transporter, putative 0.0525 0.166 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0015 0.0084
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0005 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0124 0.0358 0.0357
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0032 0.0057 0.0056
Schistosoma mansoni ap endonuclease 0.0018 0.0015 0.0014
Plasmodium vivax SET domain protein, putative 0.0061 0.0151 0.0909
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0023 0.0639
Schistosoma mansoni nuclear hormone receptor 0.002 0.0019 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0023 0.0639
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0124 0.0358 0.0357
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0046 0.0046
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0765 0.2441 1
Echinococcus multilocularis nAChR subunit 0.0021 0.0023 0.0022
Schistosoma mansoni amine GPCR 0.0124 0.0358 0.0357
Brugia malayi Cytochrome P450 family protein 0.003 0.0051 0.005
Echinococcus granulosus neuropeptide receptor A26 0.103 0.3301 0.33
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0019 0.0018
Schistosoma mansoni amine GPCR 0.0663 0.2108 0.2107
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.031 0.1266
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0109 0.031 0.1868
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi steroid hormone receptor 0.002 0.0019 0.0018
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0005 0.0004
Echinococcus granulosus dro:myosuppressin receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0765 0.2441 0.2441
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus granulosus lamin 0.0053 0.0127 0.0126
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.03 0.8857
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0021 0.0023 0.0022
Brugia malayi Cation transporter family protein 0.0021 0.0023 0.0022
Schistosoma mansoni sodium-dependent amino acid transporter 0.0525 0.166 0.1659
Schistosoma mansoni hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.023 0.0229
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0019 0.0018
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0525 0.166 0.1659
Echinococcus granulosus sodium and chloride dependent glycine 0.0525 0.166 0.1659
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Onchocerca volvulus 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0082 0.0221 0.022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Echinococcus multilocularis GPCR, family 2 0.0016 0.0005 0.0004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.035 0.1093 0.1092
Schistosoma mansoni rab6-interacting 0.006 0.0151 0.015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0019 0.0018
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0023 0.0639
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.031 0.1266
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0024 0.0024
Schistosoma mansoni lipoxygenase 0.0361 0.1129 0.1128
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0358 0.0357
Toxoplasma gondii exonuclease III APE 0.0018 0.0015 0.0088
Brugia malayi putative neuropeptide receptor NPR1 0.0124 0.0358 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0019 0.0018
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0008 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0146 0.0145
Loa Loa (eye worm) ACC-1 protein 0.0021 0.0023 0.0022
Brugia malayi ecdysteroid receptor 0.002 0.0019 0.0018
Schistosoma mansoni hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Toxoplasma gondii hypothetical protein 0.0525 0.166 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0015 0.0014
Echinococcus multilocularis sodium and chloride dependent glycine 0.0525 0.166 0.1659
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0004
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Brugia malayi Thioredoxin reductase 0.0047 0.0106 0.0105
Loa Loa (eye worm) glutathione reductase 0.0047 0.0106 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0145 0.0426 0.0425
Leishmania major cytochrome p450-like protein 0.003 0.0051 0.0203
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0221 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0338 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.03 0.8857
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0029 0.0912
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.0782 0.0781
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0004
Echinococcus granulosus fmrfamide receptor 0.0124 0.0358 0.0357
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0029 0.0835
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.3091 1 1
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0046 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0098 0.0273 0.8054
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0023 0.0698
Brugia malayi MAP kinase sur-1 0.005 0.0117 0.0116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0124 0.0358 0.0357
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0023 0.0022
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0023 0.0088
Onchocerca volvulus 0.0124 0.0358 0.0357
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0102 0.0285 0.1925
Loa Loa (eye worm) hypothetical protein 0.0076 0.02 0.0199
Leishmania major trypanothione reductase 0.0047 0.0106 0.0429
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0007 0.0039
Schistosoma mansoni histamine h1 receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0124 0.0358 0.0357
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0114 0.0113
Echinococcus granulosus dnaJ subfamily B 0.1207 0.3877 0.3877
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.031 0.1266
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.003 0.0029
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Onchocerca volvulus 0.0197 0.0594 0.0593
Loa Loa (eye worm) hypothetical protein 0.01 0.0279 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0021 0.0023 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.1207 0.3877 0.3877
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0358 0.0357
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0023 0.0698
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0358 0.0357
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Brugia malayi Serotonin receptor 0.0124 0.0358 0.0357
Schistosoma mansoni lamin 0.0053 0.0127 0.0126
Toxoplasma gondii endonuclease IV APN 0.0076 0.02 0.1205
Onchocerca volvulus 0.0124 0.0358 0.0357
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0029 0.0835
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0007 0.0024
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0525 0.166 0.1659
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0029 0.0174
Loa Loa (eye worm) hypothetical protein 0.0197 0.0594 0.0593
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0525 0.166 0.1659
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0007 0.0006
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0023 0.0698
Echinococcus granulosus peptide allatostatin:somatostatin 0.0124 0.0358 0.0357
Echinococcus multilocularis G-protein coupled receptor, putative 0.0124 0.0358 0.0357
Echinococcus granulosus somatostatin receptor 0.0124 0.0358 0.0357
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0007 0.0024
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Brugia malayi RE15519p 0.0124 0.0358 0.0357
Echinococcus multilocularis Ankyrin 0.0029 0.0047 0.0046
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0024 0.0158
Brugia malayi larval opioid receptor 0.0124 0.0358 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0117 0.0476
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0029 0.017
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus granulosus neuropeptide s receptor 0.103 0.3301 0.33
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.03 0.8857
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0151 0.0151
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0019 0.0018
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0525 0.166 0.1659
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0019 0.0018
Onchocerca volvulus 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0124 0.0358 0.0357
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0019 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0182 0.0546 0.0545
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0015 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0007 0.0171
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0124 0.0358 0.0357
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0151 0.0151
Onchocerca volvulus 0.0124 0.0358 0.0357
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0007 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.103 0.3301 0.33
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0024 0.0024
Loa Loa (eye worm) ACC-1 protein 0.0021 0.0023 0.0022
Onchocerca volvulus 0.0124 0.0358 0.0357
Loa Loa (eye worm) AGC/PKG protein kinase 0.0015 0.0003 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0019 0.0018
Brugia malayi Dopamine receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0051 0.005
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.031 0.1266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0019 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0117 0.0787
Onchocerca volvulus 0.0124 0.0358 0.0357
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0015 0.0055
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0124 0.0358 0.0357
Brugia malayi Egg laying defective protein 4 0.0015 0.0003 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.0124 0.0358 0.0357
Onchocerca volvulus 0.006 0.0151 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0029 0.0739
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0015 0.0003 0.0016
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0221 0.022
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0338 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0124 0.0358 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0127 0.0126
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0021 0.0023 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.103 0.3301 0.33
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0019 0.0018
Echinococcus granulosus nuclear factor of activated T cells 5 0.0145 0.0426 0.0425
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0004
Trichomonas vaginalis inositol monophosphatase, putative 0.0109 0.031 0.2095
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0358 0.0357
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0038 0.0037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0138 0.0138
Schistosoma mansoni opsin-like receptor 0.0124 0.0358 0.0357
Brugia malayi Cyclic-nucleotide gated cation channel 0.0022 0.0024 0.0024
Brugia malayi G-protein coupled receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0022 0.0024 0.0024
Schistosoma mansoni neuropeptide receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) doublecortin family protein 0.006 0.0151 0.015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0525 0.166 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0053 0.0354
Echinococcus granulosus neuropeptide FF receptor 2 0.0124 0.0358 0.0357
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0029 0.017
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Treponema pallidum sodium- and chloride- dependent transporter 0.3091 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Brugia malayi Inositol-1 0.0109 0.031 0.0309
Brugia malayi Dopamine receptor protein 1 0.0124 0.0358 0.0357
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0024 0.0024
Plasmodium falciparum glutathione reductase 0.0016 0.0007 0.0035
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0057 0.0056
Brugia malayi Cytochrome P450 family protein 0.0059 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0023 0.0639
Brugia malayi Tachykinin-like peptides receptor 99D 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0007 0.0024
Mycobacterium ulcerans epimerase 0.002 0.0019 0.0577
Brugia malayi G-protein coupled receptor 0.0124 0.0358 0.0357
Echinococcus granulosus hypothetical protein 0.0872 0.2789 0.2788
Echinococcus multilocularis somatostatin receptor 0.0124 0.0358 0.0357
Brugia malayi nuclear hormone receptor 0.002 0.0019 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0023 0.0639
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0023 0.0698
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0015 0.0014
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0117 0.0116
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus multilocularis RUN 0.006 0.0151 0.015
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0024 0.0024
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0525 0.166 0.1659
Echinococcus granulosus alpha 1A adrenergic receptor 0.0124 0.0358 0.0357
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0525 0.166 1
Echinococcus multilocularis microtubule associated protein 2 0.1375 0.4421 0.4421
Brugia malayi Serotonin receptor 0.0623 0.1978 0.1978
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.003 0.0029
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0023 0.0639
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0358 0.0357
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0021 0.0023 0.0022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0525 0.166 0.1659
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0525 0.166 0.1659
Echinococcus multilocularis G protein coupled receptor 139 0.0124 0.0358 0.0357
Schistosoma mansoni intermediate filament proteins 0.0053 0.0127 0.0126
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.006 0.0151 0.015
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0117 0.0116
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0023 0.0698
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni neuropeptide receptor 0.0124 0.0358 0.0357
Schistosoma mansoni sodium/chloride dependent transporter 0.0525 0.166 0.1659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0117 0.0476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0024 0.0024
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0015 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Schistosoma mansoni lamin 0.0053 0.0127 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0019 0.0018
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.3091 1 1
Schistosoma mansoni neuropeptide receptor 0.0124 0.0358 0.0357
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0007 0.0006
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Echinococcus granulosus allatostatin A receptor 0.0124 0.0358 0.0357
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0242 0.0241
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0019 0.0018
Echinococcus granulosus FTZ F1 alpha 0.002 0.0019 0.0018
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0019 0.0018
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0007 0.0186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0023 0.0022
Onchocerca volvulus 0.0525 0.166 0.1659
Brugia malayi neuropeptide F receptor 0.0124 0.0358 0.0357
Schistosoma mansoni loxhd1 0.006 0.0151 0.015
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.03 0.8857
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0151 0.0151
Echinococcus granulosus 7TM GPCR rhodopsin 0.0124 0.0358 0.0357
Onchocerca volvulus 0.006 0.0151 0.015
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0106 0.0429
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0024 0.0024
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.0028 0.0046 0.0046
Echinococcus granulosus orexin receptor type 2 0.0124 0.0358 0.0357
Mycobacterium ulcerans endonuclease IV 0.0076 0.02 0.6434
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Brugia malayi Cation transporter family protein 0.0197 0.0594 0.0593
Echinococcus multilocularis conserved hypothetical protein 0.0748 0.2385 0.2384
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.02 0.1198
Echinococcus multilocularis g-protein coupled receptor 0.0124 0.0358 0.0357
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0525 0.166 0.1659
Echinococcus granulosus g protein coupled receptor 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.006 0.0151 0.015
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0023 0.0639
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.01 0.028 0.0279
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0124 0.0358 0.0357
Schistosoma mansoni alpha-1 adrenergic receptor 0.0124 0.0358 0.0357
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0023 0.0698
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0034
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0021 0.0023 0.0022
Echinococcus multilocularis geminin 0.0334 0.1038 0.1038
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0021 0.0023 0.0022
Brugia malayi Cytochrome P450 family protein 0.003 0.0051 0.005
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0029 0.0115
Echinococcus multilocularis glycine receptor subunit beta 0.0021 0.0023 0.0022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0024 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0358 0.0357
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0358 0.0357
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0151 0.0151
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0102 0.0285 0.1925
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0117 0.0787
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0021 0.0023 0.0022
Echinococcus multilocularis sodium and chloride dependent glycine 0.0525 0.166 0.1659
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0358 0.0357
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0023 0.0698
Echinococcus multilocularis allatostatin A receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Echinococcus multilocularis orexin receptor type 2 0.0124 0.0358 0.0357
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0024
Trypanosoma brucei trypanothione reductase 0.0047 0.0106 0.0429
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0023 0.0022
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0019 0.0018
Onchocerca volvulus 0.0124 0.0358 0.0357
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0109 0.031 0.2095
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0019 0.0018
Plasmodium falciparum thioredoxin reductase 0.0016 0.0007 0.0035
Echinococcus granulosus neuropeptide receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis serotonin receptor 0.0124 0.0358 0.0357
Trypanosoma brucei C-8 sterol isomerase, putative 0.0765 0.2441 1
Brugia malayi G protein-coupled receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis lamin dm0 0.0053 0.0127 0.0126
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0007 0.0024
Loa Loa (eye worm) RecQ helicase 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0573 0.1816 0.1816
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0124 0.0358 0.0357
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0007 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0106 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0151 0.015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Chlamydia trachomatis endonuclease IV 0.0076 0.02 0.1198
Brugia malayi GnHR receptor homolog 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0033 0.0063 0.0062
Echinococcus granulosus g-protein coupled receptor 0.0124 0.0358 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0526 0.3562
Trypanosoma brucei cytochrome P450, putative 0.003 0.0051 0.0203
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0117 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0358 0.0357
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0019 0.0018
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Onchocerca volvulus 0.002 0.0019 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0151 0.0151
Echinococcus granulosus inositol monophosphatase 1 0.0109 0.031 0.0309
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0023 0.0698
Onchocerca volvulus 0.0525 0.166 0.1659
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Echinococcus granulosus microtubule associated protein 2 0.1375 0.4421 0.4421
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0023 0.0698
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.0782 0.0781
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0361 0.1129 0.1128
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0525 0.166 1
Brugia malayi cytochrome P450 0.0021 0.0023 0.0022
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0019 0.0018
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0242 0.0241
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0117 0.0706
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0023 0.0639
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0015 0.0055
Leishmania major cytochrome p450-like protein 0.0021 0.0023 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni hypothetical protein 0.0124 0.0358 0.0357
Onchocerca volvulus Neuropeptide F receptor homolog 0.0124 0.0358 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0019 0.0018
Mycobacterium leprae conserved hypothetical protein 0.002 0.0019 0.0529
Loa Loa (eye worm) hypothetical protein 0.0032 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0525 0.166 0.1659
Echinococcus granulosus cpg binding protein 0.009 0.0246 0.0245
Echinococcus granulosus g protein coupled receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0197 0.0594 0.0593
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0047 0.0046
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Plasmodium falciparum thioredoxin reductase 0.0047 0.0106 0.0631
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0063 0.0062
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0019 0.0018
Echinococcus granulosus g protein coupled receptor 0.0124 0.0358 0.0357
Mycobacterium leprae putative cytochrome p450 0.0021 0.0023 0.0639
Toxoplasma gondii thioredoxin reductase 0.0047 0.0106 0.0638
Onchocerca volvulus 0.0468 0.1476 0.1476
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0525 0.166 1
Schistosoma mansoni neuropeptide receptor 0.0124 0.0358 0.0357
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0525 0.166 0.1659
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0023 0.0639
Brugia malayi SET domain containing protein 0.0015 0.0004 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0117 0.0787
Brugia malayi Pre-SET motif family protein 0.0061 0.0151 0.0151
Echinococcus multilocularis neuropeptide FF receptor 2 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0097 0.0271 0.027
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi Pre-SET motif family protein 0.0412 0.1292 0.1291
Schistosoma mansoni amine GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0358 0.0357
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0023 0.0022
Brugia malayi M-phase phosphoprotein, mpp8 0.01 0.0279 0.0278
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0109 0.031 1
Brugia malayi ORL1-like opioid receptor 0.0124 0.0358 0.0357
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0109 0.0308 0.0307
Schistosoma mansoni inositol monophosphatase 0.0109 0.031 0.0309
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0197 0.0594 0.0593
Schistosoma mansoni hypothetical protein 0.0334 0.1038 0.1038
Echinococcus granulosus sodium and chloride dependent glycine 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trichomonas vaginalis helicase, putative 0.0019 0.0017 0.0106
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0021 0.0023 0.0022
Echinococcus multilocularis expressed conserved protein 0.0015 0.0003 0.0002
Echinococcus granulosus death domain containing protein 0.0028 0.0046 0.0046
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0021 0.0023 0.0022
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0117 0.0116
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.003 0.0029
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi AKH receptor 0.0124 0.0358 0.0357
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni amine GPCR 0.0124 0.0358 0.0357
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0114 0.0113
Schistosoma mansoni biogenic amine (5HT) receptor 0.0124 0.0358 0.0357
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0197 0.0594 0.0593
Echinococcus granulosus RUN 0.006 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Trypanosoma brucei protein kinase, putative 0.005 0.0117 0.0476
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0109 0.0308 0.0307
Onchocerca volvulus 0.0053 0.0127 0.0126
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0014 0.0079
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0021 0.0023 0.0022
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0097 0.0271 0.027
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0022 0.0024 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0029 0.0115
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus neuropeptide receptor 0.0124 0.0358 0.0357
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0124 0.0358 0.0357
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0271 0.027
Echinococcus multilocularis 0.0021 0.0023 0.0022
Echinococcus granulosus serotonin transporter 0.3091 1 1
Onchocerca volvulus 0.0072 0.0188 0.0187
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0151 0.0912
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0358 0.0357
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0021 0.0023 0.0022
Schistosoma mansoni netrin receptor unc5 0.0028 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0019 0.0018
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0021 0.0023 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0024 0.0024
Brugia malayi Dopamine receptor protein 2 0.0124 0.0358 0.0357
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0007
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Brugia malayi putative neuropeptide receptor 0.0124 0.0358 0.0357
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0007 0.0496
Loa Loa (eye worm) serotonin transporter b 0.3091 1 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0124 0.0358 0.0357
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0007 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.0119 0.0341 0.034
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.02 0.5893
Echinococcus multilocularis Polycystic kidney disease protein 0.006 0.0151 0.015
Schistosoma mansoni biogenic amine receptor 0.0124 0.0358 0.0357
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0015 0.0081
Leishmania major C-8 sterol isomerase-like protein 0.0765 0.2441 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0004
Brugia malayi hypothetical protein 0.0525 0.166 0.1659
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0412 0.1292 0.1291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Echinococcus granulosus tumor protein p63 0.0665 0.2116 0.2115
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0023 0.0698
Echinococcus granulosus geminin 0.0334 0.1038 0.1038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni adenoreceptor 0.0124 0.0358 0.0357
Echinococcus granulosus tm gpcr rhodopsin 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0023 0.0698
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus glycine receptor subunit beta 0.0021 0.0023 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0163 0.0483 0.2912
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0029 0.0177
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0023 0.0698
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0023 0.0639
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0047 0.0046
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0014 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Onchocerca volvulus 0.0124 0.0358 0.0357
Echinococcus granulosus sex peptide receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis voltage gated potassium channel 0.0032 0.0057 0.0056
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0015 0.0055
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0525 0.166 0.1659
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.002 0.0127
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0015 0.0432
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0007 0.0035
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0021 0.0023 0.0022
Onchocerca volvulus 0.0053 0.0127 0.0126
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0117 0.0116
Brugia malayi Cytochrome P450 family protein 0.0021 0.0023 0.0022
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0019 0.0018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0525 0.166 0.1659
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0525 0.166 0.1659
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0023 0.0639
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0007 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus multilocularis serotonin receptor 0.0124 0.0358 0.0357
Leishmania major cytochrome p450-like protein 0.0021 0.0023 0.0088
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Plasmodium vivax multidomain scavenger receptor, putative 0.006 0.0151 0.0905
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0023 0.0639
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0046 0.0046
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0047 0.0046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0124 0.0358 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0019 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0117 0.0787
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Mycobacterium tuberculosis Probable reductase 0.0106 0.03 0.8857
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0497 0.3363
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0007 0.0024
Brugia malayi follicle stimulating hormone receptor 0.035 0.1093 0.1092
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0525 0.166 0.1659
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0029 0.0028
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0007 0.0024
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0003 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0019 0.0018
Schistosoma mansoni thyroid hormone receptor 0.002 0.0019 0.0018
Schistosoma mansoni lipoxygenase 0.0253 0.0775 0.0775
Brugia malayi CHD4 protein 0.0016 0.0007 0.0006
Treponema pallidum NADH oxidase 0.0016 0.0007 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis dro:myosuppressin receptor 0.0124 0.0358 0.0357
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0188 0.0187
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0022 0.0024 0.0024
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0021 0.0023 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0021 0.0023 0.0022
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0358 0.0357
Brugia malayi hypothetical protein 0.01 0.028 0.0279
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0124 0.0358 0.0357
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0019 0.0018
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0124 0.0358 0.0357
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0023 0.0088
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0019 0.0577
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0358 0.0357
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0015 0.0091
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0242 0.0241
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.0046 0.0046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0114 0.0113
Schistosoma mansoni hypothetical protein 0.1207 0.3877 0.3877
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.001 0.0009
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0024 0.0024
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0117 0.0116
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0015 0.0055
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0015 0.0396
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0023 0.0022
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0003 0.0002
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0124 0.0358 0.0357
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0525 0.166 0.1659
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0358 0.0357
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0032 0.0057 0.0056
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0021 0.0023 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0019 0.0018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0124 0.0358 0.0357
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0015 0.0251
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0358 0.0357
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0051 0.0203
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0338 1
Loa Loa (eye worm) LGC-31 protein 0.0021 0.0023 0.0022
Schistosoma mansoni polycystin 1-related 0.006 0.0151 0.015
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0047 0.0046
Onchocerca volvulus 0.01 0.0279 0.0278
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.003 0.0029
Echinococcus multilocularis tumor protein p63 0.0665 0.2116 0.2115
Onchocerca volvulus 0.01 0.0279 0.0278
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0023 0.0698
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0338 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0119 0.0341 0.034
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0021 0.0023 0.0022
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0019 0.0018
Brugia malayi Death domain containing protein 0.0028 0.0046 0.0046
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0117 0.0476
Loa Loa (eye worm) hypothetical protein 0.0573 0.1816 0.1816
Loa Loa (eye worm) norepinephrine transporter 0.3091 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Brugia malayi sulfakinin receptor protein 0.0124 0.0358 0.0357
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0117 0.0476
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0015 0.0091
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0001 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0124 0.0358 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Brugia malayi neuropeptide F receptor 0.0124 0.0358 0.0357
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0106 0.3105
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0782 0.5292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.3091 1 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0109 0.031 1
Brugia malayi Doublecortin family protein 0.006 0.0151 0.015
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0023 0.0639
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0124 0.0358 0.0357
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0021 0.0023 0.0022
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni cpg binding protein 0.009 0.0246 0.0245
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0019 0.0018
Brugia malayi Cation transporter family protein 0.0021 0.0023 0.0022
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0124 0.0358 0.0357
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.003 0.0029
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0023 0.0088
Brugia malayi glutathione reductase 0.0047 0.0106 0.0105
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.001 0.0009
Schistosoma mansoni biogenic amine receptor 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0021 0.0023 0.0022
Schistosoma mansoni coup transcription factor 0.002 0.0019 0.0018
Loa Loa (eye worm) cytochrome P450 0.0021 0.0023 0.0022
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0024 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0358 0.0357
Brugia malayi intermediate filament protein 0.0053 0.0127 0.0126
Leishmania major protein kinase, putative 0.0015 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0007
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0021 0.0023 0.0022
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0003 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0046 0.0046
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0391 0.1226 0.1225
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0007 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0023 0.0639
Echinococcus granulosus serotonin receptor 0.0124 0.0358 0.0357
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0023 0.0698
Loa Loa (eye worm) inositol-1 0.0109 0.031 0.0309
Loa Loa (eye worm) solute carrier family 6 member 4 0.3091 1 1
Leishmania major protein kinase, putative 0.0015 0.0003 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0082 0.0221 0.022
Plasmodium vivax hypothetical protein, conserved 0.0525 0.166 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Schistosoma mansoni cpg binding protein 0.009 0.0246 0.0245
Schistosoma mansoni opsin-like receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0019 0.0018
Echinococcus granulosus lamin dm0 0.0053 0.0127 0.0126
Echinococcus multilocularis serotonin transporter 0.3091 1 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0023 0.0088
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0023 0.0698
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0007 0.0035
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0098 0.0273 0.8054
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0358 0.0357
Schistosoma mansoni nAChR subunit 0.0021 0.0023 0.0022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.03 0.8857
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0019 0.0018
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0109 0.0308 0.0307
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0038 0.0037
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0117 0.0116
Schistosoma mansoni ap endonuclease 0.0018 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.3091 1 1
Echinococcus granulosus nAChR subunit 0.0021 0.0023 0.0022
Plasmodium falciparum amino acid transporter, putative 0.0525 0.166 1
Onchocerca volvulus 0.3091 1 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0127 0.0126
Schistosoma mansoni biogenic amine (5HT) receptor 0.0124 0.0358 0.0357
Echinococcus multilocularis glycine receptor subunit beta 0.0021 0.0023 0.0022
Brugia malayi hypothetical protein 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0182 0.0547 0.0547
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0023 0.0698
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0006
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0109 0.0308 0.0307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0019 0.0018
Plasmodium falciparum cGMP-dependent protein kinase 0.0015 0.0003 0.0009
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0221 0.022
Plasmodium vivax amine transporter, putative 0.0525 0.166 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0019 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0019 0.0018
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0007
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0106 0.0105
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0525 0.166 0.1659
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0358 0.0357
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0023 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0024 0.0158
Brugia malayi hypothetical protein 0.006 0.0151 0.015
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0242 0.0241
Echinococcus multilocularis inositol monophosphatase 1 0.0109 0.031 0.0309
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0023 0.0698
Trichomonas vaginalis set domain proteins, putative 0.0468 0.1476 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0023 0.0137
Loa Loa (eye worm) melatonin receptor type 1A 0.0124 0.0358 0.0357
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0117 0.0476
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0053 0.0354
Onchocerca volvulus 0.0124 0.0358 0.0357
Echinococcus granulosus G protein coupled receptor 139 0.0124 0.0358 0.0357
Schistosoma mansoni cpg binding protein 0.0085 0.023 0.0229
Loa Loa (eye worm) hypothetical protein 0.0049 0.0114 0.0113
Echinococcus granulosus Polycystic kidney disease protein 0.006 0.0151 0.015
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0007
Echinococcus multilocularis musashi 0.0053 0.0127 0.0126
Brugia malayi nuclear receptor NHR-88 0.002 0.0019 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0024 0.0158
Echinococcus granulosus intermediate filament protein 0.0053 0.0127 0.0126
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0019 0.0018
Echinococcus granulosus tachykinin peptides receptor 99D 0.0124 0.0358 0.0357
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.02 0.1202
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0007 0.0024
Schistosoma mansoni neuropeptide f receptor 76f 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0124 0.0358 0.0357
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.02 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0002
Echinococcus granulosus netrin receptor unc 5 0.0028 0.0046 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0002
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0221 0.022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0124 0.0358 0.0357
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0023 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0019 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0007 0.0024
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0124 0.0358 0.0357
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.0046 0.0046
Toxoplasma gondii hypothetical protein 0.0525 0.166 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0019 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Echinococcus granulosus GPCR family 2 0.0016 0.0005 0.0004
Echinococcus multilocularis lamin 0.0053 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0022
Brugia malayi CXXC zinc finger family protein 0.0085 0.023 0.0229
Echinococcus granulosus glycine receptor subunit beta 0.0021 0.0023 0.0022
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0525 0.166 0.1659
Schistosoma mansoni rab6-interacting 0.006 0.0151 0.015
Schistosoma mansoni cytochrome P450 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0151 0.0151
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0051 0.0203
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0019 0.0529
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0117 0.0476
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0029 0.0177
Onchocerca volvulus 0.0124 0.0358 0.0357
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0106 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0019 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0019 0.0018
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0021 0.0023 0.0022
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0021 0.0023 0.0022
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.02 0.5893
Onchocerca volvulus 0.0124 0.0358 0.0357
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0525 0.166 0.1659
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0007 0.0039
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0021 0.0023 0.0022
Echinococcus multilocularis cpg binding protein 0.009 0.0246 0.0245
Onchocerca volvulus 0.0085 0.023 0.0229
Schistosoma mansoni hypothetical protein 0.0033 0.0063 0.0062
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0358 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0019 0.0018
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0109 0.031 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0358 0.0357
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0525 0.166 0.1659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0151 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0019 0.0018
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0014 0.0001 0.0007
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0007 0.0039
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0019 0.0018
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0117 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0017 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0526 0.3562
Plasmodium vivax glutathione reductase, putative 0.0047 0.0106 0.0635
Schistosoma mansoni microtubule-associated protein tau 0.1375 0.4421 0.4421
Schistosoma mansoni biogenic amine receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0047 0.0046
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0057 0.0056
Onchocerca volvulus 0.0197 0.0594 0.0593
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0124 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0023 0.0639
Onchocerca volvulus 0.0197 0.0594 0.0593
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0023 0.0022
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0124 0.0358 0.0357
Onchocerca volvulus 0.0021 0.0023 0.0022
Mycobacterium ulcerans hypothetical protein 0.002 0.0019 0.0577
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0357
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0023 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0124 0.0358 0.0357
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0021 0.0023 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.0124 0.0358 0.0357
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0497 0.0496

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) 0 Inhibitory Activity of the compound against 5-Lipoxygenase was determined; IA=Inactive ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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