Detailed information for compound 443714

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 513.536 | Formula: C27H31NO9
  • H donors: 0 H acceptors: 4 LogP: 3.47 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: COCCOCOc1c(C/C=C(/CCC(=O)OC)\C)c(OC(=O)c2cccnc2)c(c2c1C(=O)OC2)C
  • InChi: 1S/C27H31NO9/c1-17(8-10-22(29)33-4)7-9-20-24(37-26(30)19-6-5-11-28-14-19)18(2)21-15-35-27(31)23(21)25(20)36-16-34-13-12-32-3/h5-7,11,14H,8-10,12-13,15-16H2,1-4H3/b17-7+
  • InChiKey: VRFAVOZOMFIVDW-REZTVBANSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0326 0.0927 0.0903
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0128 0.0907
Schistosoma mansoni Neurotrimin precursor (hNT) 0.008 0.0048 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0318 0.0899 0.2582
Giardia lamblia Kinase, CDC7 0.0348 0.1008 0.7824
Trichomonas vaginalis AGC family protein kinase 0.0279 0.0759 0.5868
Echinococcus granulosus titin 0.0089 0.0079 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0524 0.1228
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0318 0.0899 0.0876
Toxoplasma gondii AGC kinase 0.0292 0.0806 0.6236
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0176 0.0392 0.0366
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.024 0.062 0.1779
Schistosoma mansoni ste20-related kinase 0.0221 0.0552 0.1296
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0128 0.0907
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Brugia malayi cell division control protein 2 homolog 0.0318 0.0899 0.0876
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0104 0.0136 0.039
Brugia malayi Protein kinase domain containing protein 0.0181 0.0409 0.0384
Leishmania major protein kinase, putative 0.0279 0.0759 0.5868
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.0414 0.1297
Echinococcus multilocularis CDC7 cell division cycle 7 0.0348 0.1008 0.2893
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.03 0.0836 0.0812
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.0414 0.1297
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0118 0.0185 0.1358
Loa Loa (eye worm) CDC7 protein kinase 0.0348 0.1008 0.0984
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0119 0.0188 0.0539
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0103 0.0131 0.0933
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0234 0.1743
Loa Loa (eye worm) hypothetical protein 0.0118 0.0184 0.0158
Loa Loa (eye worm) hypothetical protein 0.0588 0.1864 0.1842
Echinococcus multilocularis calcium activated potassium channel 0.0152 0.0307 0.088
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0406 0.1216 0.349
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0485 0.1134
Echinococcus multilocularis NCK adaptor protein 0.0098 0.0114 0.0326
Echinococcus multilocularis dual specificity protein kinase clk2 0.0426 0.1285 0.3687
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1041 0.3484 1
Toxoplasma gondii AGC kinase 0.03 0.0836 0.647
Trypanosoma brucei polo-like protein kinase 0.0285 0.078 0.6035
Schistosoma mansoni tyrosine kinase 0.0349 0.101 0.2396
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.03 0.0836 0.647
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0108 0.0148 0.1063
Loa Loa (eye worm) hypothetical protein 0.0095 0.0103 0.0077
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0252 0.0663 0.1902
Loa Loa (eye worm) hypothetical protein 0.0108 0.0148 0.0122
Entamoeba histolytica protein kinase domain containing protein 0.0936 0.3109 1
Trichomonas vaginalis AGC family protein kinase 0.0279 0.0759 0.5868
Onchocerca volvulus 0.0348 0.1008 0.2837
Schistosoma mansoni tyrosine kinase 0.024 0.062 0.1458
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0156 0.0321 0.2426
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0233 0.0596 0.0571
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Plasmodium falciparum serine/threonine protein kinase KIN 0.0108 0.0148 0.1063
Schistosoma mansoni ephrin receptor 0.012 0.0192 0.0431
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0152 0.0306 0.0878
Schistosoma mansoni tyrosine kinase 0.0451 0.1375 0.3272
Brugia malayi hypothetical protein 0.0216 0.0535 0.051
Loa Loa (eye worm) hypothetical protein 0.0095 0.0103 0.0077
Loa Loa (eye worm) TK protein kinase 0.0143 0.0276 0.025
Echinococcus granulosus c src tyrosine kinase 0.0154 0.0312 0.0896
Echinococcus multilocularis tyrosine protein kinase Src64B 0.024 0.062 0.1779
Schistosoma mansoni protein kinase 0.0262 0.07 0.165
Loa Loa (eye worm) SRC-1 0.024 0.062 0.0595
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0102 0.0126 0.089
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0133 0.0238 0.0682
Echinococcus granulosus epidermal growth factor receptor 0.061 0.1944 0.5579
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0202 0.0485 0.1392
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0148 0.0325
Schistosoma mansoni serine/threonine kinase 0.0171 0.0373 0.0866
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0171 0.0373 0.1072
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.014 0.0263 0.0237
Entamoeba histolytica protein kinase, putative 0.0119 0.0188 0.0566
Plasmodium vivax unspecified product 0.0118 0.0185 0.1358
Echinococcus granulosus N chimaerin 0.0097 0.0109 0.0313
Loa Loa (eye worm) hypothetical protein 0.0136 0.0248 0.0222
Loa Loa (eye worm) hypothetical protein 0.0216 0.0535 0.051
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0663 0.1561
Trichomonas vaginalis AGC family protein kinase 0.01 0.012 0.0845
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0128 0.0907
Schistosoma mansoni tyrosine kinase 0.026 0.0693 0.1635
Plasmodium falciparum cGMP-dependent protein kinase 0.0152 0.0306 0.2306
Brugia malayi Kinase associated domain 1 family protein 0.01 0.0119 0.0093
Echinococcus granulosus Vam6:Vps39 protein 0.0216 0.0535 0.1535
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Entamoeba histolytica protein kinase, putative 0.0348 0.1009 0.3217
Echinococcus multilocularis serine:threonine protein kinase N2 0.0127 0.0216 0.062
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0727 0.1715
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Echinococcus granulosus cGMP dependent protein kinase 1 0.0152 0.0306 0.0878
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0118 0.0185 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0148 0.0325
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0406 0.1214 0.3483
Entamoeba histolytica protein kinase, putative 0.0102 0.0126 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0079 0.0053
Echinococcus granulosus expressed protein 0.0102 0.0126 0.0361
Echinococcus granulosus casein kinase I alpha 0.0127 0.0215 0.0617
Brugia malayi MAP kinase sur-1 0.0102 0.0128 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0188 0.0421
Echinococcus multilocularis titin 0.0089 0.0079 0.0228
Onchocerca volvulus 0.0181 0.0408 0.1102
Loa Loa (eye worm) AGC/PKN protein kinase 0.0298 0.0827 0.0803
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0096 0.0107 0.0226
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.011 0.0156 0.1127
Schistosoma mansoni tyrosine kinase 0.0552 0.1738 0.4143
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0127 0.0215 0.0189
Trypanosoma brucei aurora B kinase 0.0279 0.0759 0.5868
Brugia malayi Protein kinase domain containing protein 0.0229 0.0581 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0026 0.0033
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0292 0.0806 0.0782
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0279 0.0759 0.2178
Echinococcus multilocularis Glutaredoxin protein 5 0.0121 0.0195 0.056
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Brugia malayi p70 ribosomal S6 kinase beta 0.0292 0.0806 0.0782
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0192 0.045 0.0425
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.03 0.0836 0.647
Echinococcus granulosus tyrosine protein kinase Fyn 0.024 0.062 0.1779
Brugia malayi ephrin receptor 1 precursor 0.0087 0.0074 0.0047
Schistosoma mansoni rap gtpase-activating protein 0.0216 0.0535 0.1254
Entamoeba histolytica protein kinase, putative 0.0109 0.0151 0.0446
Loa Loa (eye worm) TK/ABL protein kinase 0.0316 0.0894 0.087
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0127 0.0215 0.0189
Trypanosoma brucei Casein kinase II 0.0118 0.0185 0.1358
Giardia lamblia Kinase, AGC PKA 0.0173 0.0383 0.2911
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0176 0.0392 0.298
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0102 0.0126 0.089
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0119 0.0188 0.0539
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.024 0.062 0.1779
Entamoeba histolytica protein kinase, putative 0.0143 0.0276 0.085
Trypanosoma cruzi aurora B kinase, putative 0.0279 0.0759 0.5868
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.014 0.0263 0.1966
Echinococcus granulosus fibroblast growth factor receptor 4 0.0251 0.0661 0.1898
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0277 0.208
Onchocerca volvulus Serine\/threonine kinase homolog 0.0285 0.078 0.2178
Entamoeba histolytica protein kinase, putative 0.009 0.0083 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.0594 0.457
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0144 0.0276 0.207
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0268 0.0723 0.2074
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0156 0.0463
Echinococcus multilocularis tyrosine protein kinase HCK 0.0143 0.0276 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.03 0.0836 0.1976
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0306 0.0704
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.024 0.062 0.1779
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0415 0.1245 0.3573
Trypanosoma cruzi casein kinase, putative 0.0127 0.0215 0.1593
Brugia malayi Protein kinase domain containing protein 0.0113 0.0168 0.0143
Onchocerca volvulus 0.0189 0.044 0.1193
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0253 0.0667 0.0643
Entamoeba histolytica p21-activated kinase 0.0113 0.0167 0.05
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0173 0.0383 0.2911
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.018 0.0408 0.0383
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0216 0.0535 0.1535
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0126 0.0272
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0202 0.0485 0.046
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0279 0.0759 0.2411
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0759 0.1793
Schistosoma mansoni serine/threonine protein kinase 0.0956 0.3181 0.7606
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0154 0.0312 0.0719
Loa Loa (eye worm) TK/EPH protein kinase 0.0137 0.0253 0.0228
Echinococcus granulosus serine:threonine protein kinase N2 0.0127 0.0216 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0026 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0318 0.0899 0.6972
Giardia lamblia Kinase, CMGC CDK 0.0318 0.0899 0.6972
Loa Loa (eye worm) hypothetical protein 0.014 0.0262 0.0236
Trypanosoma brucei SNF1-related protein kinases, putative 0.0108 0.0148 0.1063
Schistosoma mansoni protein kinase 0.0127 0.0215 0.0486
Trichomonas vaginalis STE family protein kinase 0.0153 0.0311 0.2348
Trichomonas vaginalis CMGC family protein kinase 0.0348 0.1009 0.783
Entamoeba histolytica protein kinase, putative 0.0092 0.0091 0.0255
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.014 0.0263 0.1966
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0156 0.0321 0.0296
Trichomonas vaginalis AGC family protein kinase 0.018 0.0405 0.3082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0272 0.0736 0.0711
Onchocerca volvulus 0.0113 0.0168 0.0408
Echinococcus granulosus tyrosine protein kinase HCK 0.0143 0.0276 0.0791
Echinococcus granulosus tyrosine protein kinase 0.0292 0.0806 0.2315
Echinococcus multilocularis growth factor receptor bound protein 2 0.0096 0.0107 0.0306
Echinococcus granulosus twitchin 0.0153 0.031 0.089
Leishmania major protein kinase, putative 0.0103 0.0131 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0128 0.0277
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0251 0.0661 0.1898
Echinococcus granulosus nervana 2 0.0121 0.0195 0.056
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0119 0.0188 0.1378
Echinococcus multilocularis cyclin dependent kinase 1 0.0318 0.0899 0.2582
Plasmodium falciparum calcium-dependent protein kinase 5 0.0119 0.0188 0.1378
Loa Loa (eye worm) AGC/PKA protein kinase 0.03 0.0836 0.0812
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0188 0.1378
Loa Loa (eye worm) thyroid receptor interactor 0.0114 0.0172 0.0146
Schistosoma mansoni tyrosine kinase 0.0251 0.0661 0.1558
Echinococcus multilocularis tyrosine protein kinase Blk 0.0199 0.0476 0.1366
Echinococcus granulosus casein kinase I alpha 0.0127 0.0215 0.0617
Leishmania major protein kinase, putative 0.011 0.0156 0.1127
Brugia malayi casein kinase 1, delta 0.0127 0.0215 0.0189
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0108 0.0148 0.0122
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0128 0.0907
Entamoeba histolytica protein kinase, putative 0.0156 0.0321 0.0997
Echinococcus multilocularis serine:threonine protein kinase 0.0132 0.0234 0.0672
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0133 0.0238 0.0682
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0318 0.0899 0.6972
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0348 0.1009 0.2391
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0535 0.1254
Echinococcus multilocularis casein kinase ii subunit alpha 0.0118 0.0185 0.0532
Giardia lamblia Kinase, STE STE20 0.0104 0.0136 0.097
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Schistosoma mansoni cell adhesion molecule 0.0112 0.0165 0.0365
Schistosoma mansoni vav2 0.0106 0.014 0.0307
Brugia malayi Protein kinase domain containing protein 0.0209 0.0509 0.0484
Schistosoma mansoni protein kinase 0.0104 0.0136 0.0296
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1301 0.4415 0.44
Schistosoma mansoni serine/threonine protein kinase 0.0406 0.1214 0.2884
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0232 0.059 0.1695
Echinococcus granulosus Immunoglobulin 0.008 0.0048 0.0138
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Toxoplasma gondii casein kinase I 0.0127 0.0215 0.1593
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0148 0.0325
Brugia malayi Protein kinase domain containing protein 0.0558 0.1759 0.1737
Echinococcus multilocularis 0.0424 0.1279 0.3672
Onchocerca volvulus 0.0903 0.2993 0.8579
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0279 0.0759 0.5868
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0306 0.0704
Trypanosoma cruzi cdc2-related kinase 1 0.0318 0.0899 0.6972
Echinococcus multilocularis activin receptor type 0.011 0.0156 0.0447
Echinococcus multilocularis mitogen activated protein kinase 11 0.0176 0.0392 0.1124
Trypanosoma brucei protein kinase, putative 0.011 0.0156 0.1127
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Leishmania major protein kinase, putative 0.0426 0.1285 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0271 0.0733 0.2105
Echinococcus granulosus dual specificity 0.0156 0.0321 0.0922
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0173 0.0383 0.2911
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0171 0.0373 0.1072
Echinococcus multilocularis protein tyrosine kinase 0.0552 0.1738 0.4988
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0357 0.1038 0.298
Trypanosoma cruzi casein kinase, putative 0.0127 0.0215 0.1593
Echinococcus granulosus protein kinase shaggy 0.0348 0.1009 0.2895
Brugia malayi serine/threonine kinase 12 0.0279 0.0759 0.0735
Echinococcus granulosus serine threonine protein kinase nrc 0.0173 0.0383 0.1099
Echinococcus multilocularis tyrosine protein kinase Srms 0.0199 0.0476 0.1366
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.01 0.012 0.0094
Echinococcus multilocularis mitogen activated protein kinase 14 0.0176 0.0392 0.1124
Leishmania major protein kinase, putative 0.0119 0.0188 0.1378
Echinococcus multilocularis epidermal growth factor receptor 0.0406 0.1216 0.349
Echinococcus multilocularis nervana 2 0.0121 0.0195 0.056
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0251 0.0661 0.1898
Schistosoma mansoni vesicular amine transporter 0.008 0.0048 0.0085
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0326 0.0927 0.0903
Echinococcus granulosus casein kinase ii subunit alpha 0.0118 0.0185 0.0532
Brugia malayi Protein kinase domain containing protein 0.014 0.0263 0.0237
Entamoeba histolytica protein kinase, putative 0.014 0.0263 0.0808
Brugia malayi Protein kinase domain containing protein 0.0113 0.0168 0.0143
Trypanosoma cruzi cdc2-related kinase 1 0.0318 0.0899 0.6972
Echinococcus granulosus protein kinase c iota type 0.0293 0.081 0.2324
Echinococcus granulosus dual specificity 0.0156 0.0321 0.0922
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0936 0.3109 0.3091
Echinococcus multilocularis N chimaerin 0.0097 0.0109 0.0313
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0109 0.0083
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.0414 0.0964
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Brugia malayi RhoGAP domain containing protein 0.0097 0.0109 0.0083
Echinococcus multilocularis tyrosine protein kinase shark 0.0322 0.0915 0.2626
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0104 0.0136 0.039
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0103 0.0131 0.0383
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Trichomonas vaginalis STE family protein kinase 0.0103 0.0131 0.0933
Loa Loa (eye worm) hypothetical protein 0.0096 0.0107 0.0081
Trypanosoma cruzi cdc2-related kinase 3 0.0318 0.0899 0.6972
Echinococcus multilocularis tyrosine protein kinase Src42A 0.024 0.062 0.1779
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0406 0.1214 0.3483
Echinococcus multilocularis tyrosine protein kinase Fgr 0.024 0.062 0.1779
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Brugia malayi Protein kinase domain containing protein 0.021 0.0513 0.0488
Loa Loa (eye worm) AUR protein kinase 0.0279 0.0759 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0373 0.0866
Schistosoma mansoni tyrosine kinase 0.0406 0.1216 0.2889
Echinococcus multilocularis neuroglian 0.0101 0.0122 0.0351
Entamoeba histolytica serine/threonine protein kinase, putative 0.0285 0.078 0.248
Schistosoma mansoni tyrosine kinase 0.0088 0.0078 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Echinococcus granulosus serine:threonine protein kinase N2 0.0298 0.0827 0.2373
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0176 0.0392 0.298
Brugia malayi Fibronectin type III domain containing protein 0.0095 0.0103 0.0077
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0119 0.0188 0.1378
Entamoeba histolytica protein kinase, putative 0.012 0.0192 0.058
Echinococcus granulosus hypothetical protein 0.0373 0.1097 0.3148
Brugia malayi protein kinase C3,putative 0.0174 0.0387 0.0361
Schistosoma mansoni tyrosine kinase 0.0154 0.0312 0.0719
Trichomonas vaginalis CMGC family protein kinase 0.0348 0.1009 0.783
Brugia malayi Doublecortin family protein 0.0168 0.0363 0.0337
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0285 0.078 0.0756
Loa Loa (eye worm) hypothetical protein 0.0116 0.0179 0.0153
Brugia malayi Protein kinase domain containing protein 0.0607 0.1933 0.1912
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0108 0.0148 0.1063
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Echinococcus granulosus neuroglian 0.0101 0.0122 0.0351
Loa Loa (eye worm) hypothetical protein 0.0177 0.0394 0.0369
Echinococcus granulosus NCK adaptor protein 0.0096 0.0107 0.0306
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.03 0.0836 0.647
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0253 0.0667 0.1916
Echinococcus granulosus cGMP dependent protein kinase 1 0.0152 0.0306 0.0878
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0348 0.1009 0.2895
Brugia malayi Protein kinase domain containing protein 0.0451 0.1375 0.1353
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0612 0.144
Trypanosoma cruzi casein kinase, putative 0.0127 0.0215 0.1593
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0128 0.0367
Brugia malayi Protein kinase c protein 2 0.0133 0.024 0.0214
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0104 0.0136 0.039
Brugia malayi serine/threonine-protein kinase 6 0.0279 0.0759 0.0735
Entamoeba histolytica hypothetical protein 0.0372 0.1092 0.3485
Giardia lamblia Kinase, CK1 Casein kinase 0.0127 0.0215 0.1593
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0268 0.0723 0.2074
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1041 0.3484 0.3467
Leishmania major protein kinase A catalytic subunit isoform 1 0.03 0.0836 0.647
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0348 0.1009 0.0985
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Loa Loa (eye worm) hypothetical protein 0.0136 0.0248 0.0222
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0348 0.1009 0.2895
Echinococcus granulosus growth factor receptor bound protein 2 0.0098 0.0114 0.0326
Echinococcus multilocularis serine:threonine protein kinase 3 0.0271 0.0733 0.2105
Toxoplasma gondii aurora kinase 0.0279 0.0759 0.5868
Brugia malayi protein unc-22 0.0089 0.0079 0.0053
Leishmania major casein kinase II, putative 0.0118 0.0185 0.1358
Schistosoma mansoni growth factor receptor-bound protein 0.0098 0.0114 0.0243
Echinococcus granulosus casein kinase i 0.0127 0.0215 0.0617
Entamoeba histolytica hypothetical protein 0.014 0.0263 0.0808
Brugia malayi Protein kinase domain containing protein 0.1041 0.3484 0.3467
Echinococcus granulosus casein kinase I gamma 0.0229 0.0581 0.1667
Brugia malayi SH2 domain containing protein 0.0113 0.0168 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Plasmodium vivax protein kinase Crk2 0.0318 0.0899 0.6972
Entamoeba histolytica protein kinase domain containing protein 0.0118 0.0185 0.0558
Loa Loa (eye worm) AGC/PKA protein kinase 0.03 0.0836 0.0812
Brugia malayi STE20-like kinase MST 0.0271 0.0733 0.0709
Trypanosoma brucei cdc2-related kinase 3 0.0318 0.0899 0.6972
Echinococcus granulosus cyclin dependent kinase 0.0318 0.0899 0.2582
Echinococcus multilocularis roundabout 2 0.0133 0.0239 0.0686
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0253 0.0667 0.1916
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0108 0.0148 0.1063
Loa Loa (eye worm) TK/ROR protein kinase 0.0078 0.0042 0.0016
Echinococcus granulosus roundabout 2 0.0133 0.0239 0.0686
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.03 0.0836 0.647
Echinococcus multilocularis serine:threonine protein kinase N2 0.0298 0.0827 0.2373
Brugia malayi SRC-1 0.024 0.062 0.0595
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0173 0.0383 0.1099
Schistosoma mansoni tyrosine kinase 0.0451 0.1375 0.3272
Entamoeba histolytica protein kinase, putative 0.0092 0.0091 0.0255
Giardia lamblia Kinase, CMGC SRPK 0.0102 0.0126 0.089
Brugia malayi Cam kinase protein 1 0.0119 0.0188 0.0162
Echinococcus granulosus tyrosine protein kinase Fyn 0.024 0.062 0.1779
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Brugia malayi Protein kinase domain containing protein 0.0198 0.047 0.0445
Echinococcus granulosus tyrosine protein kinase Srms 0.0512 0.1594 0.4575
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.059 0.1388
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.03 0.0836 0.647
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0188 0.0539
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0132 0.0234 0.0208
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0271 0.0733 0.0709
Echinococcus multilocularis expressed conserved protein 0.0152 0.0306 0.0878
Loa Loa (eye worm) hypothetical protein 0.0204 0.0491 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0215 0.0486
Giardia lamblia Kinase, CMGC GSK 0.0348 0.1009 0.783
Brugia malayi probable protein kinase 0.064 0.2051 0.203
Schistosoma mansoni nephrin 0.0116 0.0177 0.0395
Giardia lamblia Kinase, NEK 0.0153 0.0311 0.2348
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0535 0.4106
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1235 0.4178 0.4162
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0279 0.0759 0.0735
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0247 0.0647 0.0622
Schistosoma mansoni protein kinase C mu 0.0233 0.0596 0.1401
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0426 0.1285 1
Echinococcus granulosus aurora kinase A 0.0279 0.0759 0.2178
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0238 0.1769
Trypanosoma brucei casein kinase I, isoform 2 0.0127 0.0215 0.1593
Onchocerca volvulus 0.0136 0.0248 0.0638
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0251 0.0661 0.1898
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0279 0.0759 0.2411
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0373 0.2837
Onchocerca volvulus 0.0449 0.1366 0.3874
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0311 0.2348
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0248 0.0648 0.1859
Giardia lamblia Kinase, AGC PKA 0.03 0.0836 0.647
Loa Loa (eye worm) TK protein kinase 0.0292 0.0806 0.0782
Schistosoma mansoni tyrosine kinase 0.0154 0.0312 0.0719
Echinococcus multilocularis PAK box P21 Rho binding 0.0083 0.006 0.0172
Schistosoma mansoni titin 0.0089 0.0079 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.078 0.1843
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Loa Loa (eye worm) hypothetical protein 0.0353 0.1024 0.1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0232 0.059 0.1695
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0148 0.0325
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0152 0.0306 0.0878
Loa Loa (eye worm) hypothetical protein 0.0181 0.0408 0.0383
Trichomonas vaginalis AGC family protein kinase 0.01 0.012 0.0845
Plasmodium falciparum casein kinase 2, alpha subunit 0.0118 0.0185 0.1358
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0415 0.1245 0.3573
Schistosoma mansoni protein kinase 0.0445 0.1352 0.3217
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0121 0.0195 0.056
Loa Loa (eye worm) hypothetical protein 0.0132 0.0234 0.0208
Loa Loa (eye worm) TK/FAK protein kinase 0.0558 0.1759 0.1737
Loa Loa (eye worm) TK/INSR protein kinase 0.0451 0.1375 0.1353
Brugia malayi SH2 domain containing protein 0.041 0.1229 0.1206
Giardia lamblia Kinase, CAMK CAMKL 0.0108 0.0148 0.1063
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0188 0.0539
Plasmodium vivax serine/threonine protein kinase, putative 0.0102 0.0126 0.089
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0318 0.0899 0.6972
Echinococcus multilocularis tyrosine protein kinase 0.0292 0.0806 0.2315
Loa Loa (eye worm) hypothetical protein 0.0607 0.1933 0.1912
Brugia malayi Protein kinase domain containing protein 0.0289 0.0795 0.0771
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0307 0.0706
Echinococcus granulosus titin 0.0089 0.0079 0.0228
Leishmania major protein kinase A catalytic subunit isoform 2 0.03 0.0836 0.647
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0215 0.0617
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.03 0.0836 0.647
Schistosoma mansoni protein kinase 0.0424 0.1279 0.3041
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0344 0.0994 0.097
Entamoeba histolytica protein kinase, putative 0.01 0.012 0.0347
Schistosoma mansoni tyrosine kinase 0.0406 0.1216 0.2889
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0202 0.0485 0.1392
Brugia malayi Protein kinase domain containing protein 0.0171 0.0373 0.0348
Echinococcus granulosus defective proboscis extension response 0.008 0.0048 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0114 0.0244
Entamoeba histolytica protein kinase, putative 0.0104 0.0136 0.0399
Loa Loa (eye worm) hypothetical protein 0.014 0.0265 0.0239
Echinococcus granulosus mitogen activated protein kinase 14 0.0176 0.0392 0.1124
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1041 0.3484 1
Schistosoma mansoni tyrosine kinase 0.061 0.1944 0.4637
Schistosoma mansoni vam6/vps39 related 0.0216 0.0535 0.1254
Brugia malayi Tyrosine-protein kinase abl-1 0.0125 0.0211 0.0185
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.03 0.0836 0.647
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0119 0.0188 0.1378
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0348 0.1009 0.0985
Echinococcus multilocularis twitchin 0.0073 0.0025 0.0071
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.008 0.0048 0.0085
Schistosoma mansoni tyrosine kinase 0.0349 0.101 0.2396
Entamoeba histolytica protein kinase, putative 0.0292 0.0806 0.2562
Trichomonas vaginalis STE family protein kinase 0.0083 0.006 0.0374
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.024 0.062 0.1779
Plasmodium falciparum calcium-dependent protein kinase 2 0.0119 0.0188 0.1378
Loa Loa (eye worm) hypothetical protein 0.01 0.0119 0.0093
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0318 0.0899 0.6972
Entamoeba histolytica casein kinase, putative 0.0127 0.0215 0.0654
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0535 0.4106
Plasmodium vivax calcium-dependent protein kinase, putative 0.0119 0.0188 0.1378
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0128 0.0907
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Plasmodium falciparum casein kinase 1 0.0127 0.0215 0.1593
Plasmodium falciparum NIMA related kinase 1 0.0153 0.0311 0.2348
Echinococcus multilocularis serine:threonine protein kinase 38 0.0171 0.0373 0.1072
Brugia malayi Protein kinase domain containing protein 0.1301 0.4415 0.44
Loa Loa (eye worm) hypothetical protein 0.0265 0.0712 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0759 0.1792
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.014 0.0263 0.1966
Loa Loa (eye worm) hypothetical protein 0.0097 0.011 0.0084
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Echinococcus multilocularis dual specificity 0.014 0.0263 0.0754
Plasmodium vivax tyrosine kinase-like protein, putative 0.01 0.0118 0.0833
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2863 1 1
Onchocerca volvulus 0.0348 0.1009 0.2839
Schistosoma mansoni protein kinase 0.0118 0.0185 0.0415
Echinococcus multilocularis protein kinase c iota type 0.0293 0.081 0.2324
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0262 0.07 0.2008
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0102 0.0126 0.089
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0128 0.0907
Plasmodium vivax glycogen synthase kinase 3, putative 0.0348 0.1009 0.783
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0215 0.1593
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0176 0.0392 0.298
Brugia malayi Protein kinase domain containing protein 0.0232 0.0594 0.0569
Plasmodium vivax casein kinase 1, putative 0.0127 0.0215 0.1593
Schistosoma mansoni tyrosine kinase 0.0349 0.101 0.2396
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0373 0.2837
Loa Loa (eye worm) hypothetical protein 0.008 0.0048 0.0022
Echinococcus granulosus dual specificity 0.014 0.0263 0.0754
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0119 0.0188 0.1378
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Onchocerca volvulus 0.0956 0.3181 0.9122
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0127 0.0215 0.1593
Echinococcus granulosus ephrin type A receptor 4 A 0.012 0.0192 0.0551
Echinococcus multilocularis protein kinase shaggy 0.0348 0.1009 0.2895
Echinococcus granulosus tyrosine protein kinase Src42A 0.0144 0.0277 0.0796
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0107 0.0081
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Schistosoma mansoni nck2/grb4 0.0096 0.0107 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0176 0.0392 0.298
Schistosoma mansoni protein kinase 0.0262 0.07 0.165
Schistosoma mansoni protein kinase 0.064 0.2051 0.4895
Schistosoma mansoni growth factor receptor-bound protein 0.0096 0.0107 0.0226
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0104 0.0136 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0357 0.1038 0.2463
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Plasmodium vivax protein kinase, putative 0.0072 0.0021 0.0065
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.078 0.6035
Brugia malayi Protein kinase domain containing protein 0.0113 0.0168 0.0143
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0318 0.0899 0.0876
Echinococcus multilocularis mitogen activated protein kinase 11 0.0176 0.0392 0.1124
Onchocerca volvulus 0.0089 0.0079 0.0151
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0215 0.1593
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Loa Loa (eye worm) CAMK protein kinase 0.0089 0.0079 0.0053
Onchocerca volvulus 0.0113 0.0168 0.0408
Entamoeba histolytica cell division protein kinase 2, putative 0.0318 0.0899 0.2865
Loa Loa (eye worm) hypothetical protein 0.008 0.0049 0.0023
Schistosoma mansoni hypothetical protein 0.0216 0.0535 0.1254
Brugia malayi P38 map kinase family protein 2 0.0176 0.0392 0.0366
Brugia malayi protein kinase C II. 0.0213 0.0524 0.0499
Giardia lamblia Kinase, NEK 0.0153 0.0311 0.2348
Loa Loa (eye worm) hypothetical protein 0.0234 0.0601 0.0576
Echinococcus multilocularis tyrosine kinase 0.0113 0.0168 0.0483
Brugia malayi putative serine/threonine kinase SADA gamma 0.0108 0.0148 0.0122
Echinococcus multilocularis 0.0373 0.1097 0.3148
Echinococcus granulosus dual specificity protein kinase clk2 0.0426 0.1285 0.3687
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Brugia malayi Protein kinase domain containing protein 0.0081 0.0052 0.0025
Onchocerca volvulus 0.0095 0.0101 0.0214
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1041 0.3484 0.3467
Echinococcus granulosus Protein kinase C brain isozyme 0.0252 0.0663 0.1902
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0277 0.208
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0504 0.1564 0.4489
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0581 0.1364
Echinococcus granulosus tyrosine protein kinase Src64B 0.024 0.062 0.1779
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0936 0.3109 0.8923
Plasmodium falciparum calcium-dependent protein kinase 4 0.0119 0.0188 0.1378
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0121 0.0195 0.056
Giardia lamblia Kinase, CMGC GSK 0.0348 0.1009 0.783
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0248 0.0648 0.1859
Brugia malayi Protein kinase domain containing protein 0.0292 0.0806 0.0782
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0103 0.0131 0.0383
Schistosoma mansoni protein kinase 0.0209 0.0509 0.1193
Echinococcus granulosus tyrosine protein kinase Src42A 0.024 0.062 0.1779
Echinococcus multilocularis tyrosine protein kinase Abl 0.0231 0.0589 0.1692
Giardia lamblia Aurora kinase 0.0279 0.0759 0.5868
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0232 0.059 0.1695
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0263 0.0808
Brugia malayi hypothetical protein 0.0238 0.0612 0.0587
Entamoeba histolytica casein kinase, putative 0.0118 0.0185 0.0558
Schistosoma mansoni adapter molecule crk 0.0096 0.0107 0.0226
Echinococcus granulosus casein kinase I alpha 0.0127 0.0215 0.0617
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.1009 0.3217
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0097 0.0109 0.0232
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Toxoplasma gondii CMGC kinase, CK2 family 0.0118 0.0185 0.1358
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0153 0.0311 0.2348
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0217 0.0537 0.1541
Echinococcus multilocularis raf serine:threonine protein kinase 0.0098 0.0114 0.0328
Loa Loa (eye worm) hypothetical protein 0.0307 0.0859 0.0835
Schistosoma mansoni serine/threonine protein kinase 0.0426 0.1285 0.3054
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0102 0.0126 0.089
Schistosoma mansoni atypical protein kinase C 0.0299 0.0831 0.1965
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0162 0.0342 0.098
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0113 0.0168 0.0503
Echinococcus multilocularis dual specificity 0.0156 0.0321 0.0922
Entamoeba histolytica protein kinase, putative 0.0279 0.0759 0.2411
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0089 0.0079 0.0053
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0238 0.0612 0.1757
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0128 0.0907
Onchocerca volvulus 0.0113 0.0168 0.0408
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0168 0.0363 0.0337
Schistosoma mansoni tyrosine kinase 0.0266 0.0715 0.1686
Entamoeba histolytica protein kinase, putative 0.009 0.0083 0.0227
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0215 0.1593
Echinococcus multilocularis casein kinase I delta 0.0127 0.0215 0.0617
Brugia malayi Protein kinase domain containing protein 0.1235 0.4178 0.4162
Onchocerca volvulus 0.0113 0.0168 0.0408
Echinococcus granulosus tyrosine protein kinase Fyn 0.024 0.062 0.1779
Loa Loa (eye worm) TK/FER protein kinase 0.041 0.1229 0.1206
Brugia malayi Tyrosine-protein kinase abl-1 0.0231 0.0589 0.0565
Loa Loa (eye worm) AUR protein kinase 0.0279 0.0759 0.0735
Trichomonas vaginalis CMGC family protein kinase 0.0348 0.1008 0.7824
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0588 0.1864 0.5349
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0215 0.0617
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0535 0.1254
Brugia malayi Temporarily assigned gene name protein 59 0.0216 0.0535 0.051
Schistosoma mansoni protein kinase 0.0445 0.1352 0.3217
Brugia malayi Temporarily assigned gene name protein 59 0.0126 0.0214 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0899 0.213
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0238 0.0612 0.1757
Entamoeba histolytica protein kinase, putative 0.0279 0.0759 0.2411
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0108 0.0148 0.1063
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0406 0.1214 0.119
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0409 0.0952
Plasmodium falciparum protein kinase 5 0.0318 0.0899 0.6972
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0279 0.0759 0.2411
Trichomonas vaginalis STE family protein kinase 0.0104 0.0136 0.097
Echinococcus multilocularis c src tyrosine kinase 0.0154 0.0312 0.0896
Echinococcus granulosus serine:threonine protein kinase 0.0132 0.0234 0.0672
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0096 0.0107 0.0081
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.01 0.012 0.0345
Giardia lamblia Kinase, CMGC DYRK 0.0156 0.0321 0.2426
Echinococcus multilocularis hypothetical protein 0.01 0.0119 0.0341
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0318 0.0899 0.0876
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0171 0.0373 0.0348
Trichomonas vaginalis STE family protein kinase 0.0104 0.0136 0.097
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.01 0.0118 0.0833
Plasmodium falciparum calcium-dependent protein kinase 3 0.0119 0.0188 0.1378
Echinococcus multilocularis death associated protein kinase 1 0.085 0.2802 0.8042
Loa Loa (eye worm) hypothetical protein 0.0353 0.1024 0.1
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0181 0.0409 0.0384
Entamoeba histolytica PH domain containing protein kinase, putative 0.0309 0.0867 0.2759
Schistosoma mansoni tyrosine kinase 0.0096 0.0104 0.022
Echinococcus multilocularis casein kinase I gamma 0.0229 0.0581 0.1667
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0128 0.0907
Echinococcus multilocularis casein kinase i 0.0127 0.0215 0.0617
Plasmodium falciparum tyrosine kinase-like protein, putative 0.01 0.0118 0.0833
Toxoplasma gondii AGC kinase 0.03 0.0836 0.647
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.01 0.012 0.0345
Loa Loa (eye worm) TK/EGFR protein kinase 0.061 0.1944 0.1923
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0233 0.0596 0.0571
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.1009 0.3217
Loa Loa (eye worm) hypothetical protein 0.008 0.0048 0.0021
Echinococcus granulosus serine:threonine kinase SAD 1 0.0108 0.0148 0.0424
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0096 0.0107 0.0081
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0104 0.0136 0.039
Echinococcus multilocularis Immunoglobulin 0.008 0.0048 0.0138
Echinococcus granulosus tyrosine protein kinase ABL1 0.0316 0.0894 0.2565
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0128 0.0907
Echinococcus multilocularis myosin iiia 0.0103 0.0131 0.0377
Plasmodium falciparum protein kinase, putative 0.011 0.0156 0.1127
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0348 0.1009 0.783
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.059 0.1388
Trypanosoma brucei protein kinase, putative 0.0102 0.0128 0.0907
Plasmodium falciparum calcium-dependent protein kinase 1 0.0119 0.0188 0.1378
Trichomonas vaginalis STE family protein kinase 0.0104 0.0136 0.097
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0127 0.0215 0.0189
Entamoeba histolytica protein kinase, putative 0.03 0.0837 0.2663
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0357 0.1038 0.298
Giardia lamblia Kinase, CMGC CDK 0.0318 0.0899 0.6972
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0504 0.1564 0.4489
Loa Loa (eye worm) hypothetical protein 0.0135 0.0245 0.022
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0119 0.0188 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Schistosoma mansoni ephrin receptor 0.0073 0.0023 0.0025
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.024 0.062 0.1779
Echinococcus granulosus serine:threonine protein kinase 0.0132 0.0234 0.0672
Echinococcus granulosus mitogen activated protein kinase 11 0.0176 0.0392 0.1124
Echinococcus granulosus serine/threonine protein kinase 0.0182 0.0414 0.1189
Brugia malayi Sex muscle abnormal protein 5 0.0096 0.0107 0.0081
Trypanosoma brucei rac serine-threonine kinase, putative 0.03 0.0837 0.6482
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0663 0.1561
Schistosoma mansoni tyrosine kinase 0.024 0.062 0.1458
Loa Loa (eye worm) AGC/NDR protein kinase 0.0171 0.0373 0.0348
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0119 0.0188 0.1378
Brugia malayi Furin-like cysteine rich region family protein 0.061 0.1944 0.1923
Giardia lamblia Kinase, CAMK CAMKL 0.0108 0.0148 0.1063
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0128 0.0907
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Schistosoma mansoni protein kinase 0.0445 0.1352 0.3217
Loa Loa (eye worm) hypothetical protein 0.008 0.0048 0.0022
Echinococcus multilocularis protein kinase c epsilon type 0.0213 0.0524 0.1504
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0426 0.1285 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0199 0.0476 0.1366
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0106 0.0141 0.0115
Loa Loa (eye worm) protein kinase domain-containing protein 0.0229 0.0581 0.0556
Echinococcus granulosus casein kinase I delta 0.0127 0.0215 0.0617
Echinococcus multilocularis aurora kinase A 0.0279 0.0759 0.2178
Echinococcus granulosus raf serine:threonine protein kinase 0.0098 0.0114 0.0328
Plasmodium falciparum serine/threonine protein kinase 0.0102 0.0126 0.089
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0486 0.1499 0.4303
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0108 0.0148 0.0424
Loa Loa (eye worm) TK protein kinase 0.0354 0.1029 0.1005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.011 0.0156 0.1127
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0128 0.0907
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1007 0.3365 0.9659
Schistosoma mansoni serine/threonine protein kinase 0.0936 0.3109 0.7434
Schistosoma mansoni kinase 0.0303 0.0845 0.1998
Echinococcus multilocularis nervana 2 0.0121 0.0195 0.056
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0202 0.0485 0.046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.009 0.0083 0.0238
Brugia malayi Protein kinase domain 0.0104 0.0136 0.011
Trichomonas vaginalis AGC family protein kinase 0.0279 0.0759 0.5868
Loa Loa (eye worm) hypothetical protein 0.0119 0.0188 0.0162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0119 0.0188 0.0539
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0103 0.0131 0.0933
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Schistosoma mansoni serine/threonine protein kinase 0.1235 0.4178 1
Echinococcus granulosus calcium activated potassium channel 0.0152 0.0307 0.088
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0216 0.0535 0.051
Trichomonas vaginalis CMGC family protein kinase 0.0348 0.1008 0.7824
Brugia malayi Hr1 repeat family protein 0.0298 0.0827 0.0803
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0936 0.3109 0.8923
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0279 0.0759 0.2178
Loa Loa (eye worm) TK protein kinase 0.0199 0.0476 0.0451
Echinococcus multilocularis casein kinase I delta 0.0127 0.0215 0.0617
Brugia malayi Protein kinase domain containing protein 0.0607 0.1933 0.1912
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0285 0.078 0.224
Loa Loa (eye worm) hypothetical protein 0.0373 0.1097 0.1073
Trichomonas vaginalis CMGC family protein kinase 0.0318 0.0899 0.6972
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0899 0.213
Loa Loa (eye worm) hypothetical protein 0.0189 0.044 0.0414
Echinococcus multilocularis insulin receptor 0.0451 0.1375 0.3948
Schistosoma mansoni protein kinase 0.0104 0.0136 0.0296
Schistosoma mansoni protein kinase 0.0279 0.0759 0.1792
Entamoeba histolytica protein kinase 2, putative 0.0173 0.0383 0.1196
Loa Loa (eye worm) AUR protein kinase 0.0279 0.0759 0.0735
Leishmania major casein kinase, putative 0.0127 0.0215 0.1593
Plasmodium falciparum protein serine/threonine kinase-1 0.0426 0.1285 1
Echinococcus granulosus Glutaredoxin protein 5 0.0121 0.0195 0.056
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.011 0.0156 0.1127
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0209 0.0509 0.0484
Trichomonas vaginalis AGC family protein kinase 0.01 0.012 0.0845
Leishmania major protein kinase, putative 0.0426 0.1285 1
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0108 0.0148 0.1063
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0827 0.1955
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0097 0.0109 0.0232
Echinococcus multilocularis serine:threonine protein kinase 0.0132 0.0234 0.0672
Loa Loa (eye worm) TK/ALK protein kinase 0.0289 0.0795 0.0771
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0607 0.1933 0.1912
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0307 0.0706
Trichomonas vaginalis AGC family protein kinase 0.0279 0.0759 0.5868
Onchocerca volvulus Serine\/threonine kinase homolog 0.0181 0.0409 0.1104
Onchocerca volvulus 0.0113 0.0168 0.0408
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0109 0.0151 0.0446
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0213 0.0524 0.0499
Brugia malayi Protein kinase domain containing protein 0.0348 0.1008 0.0984
Echinococcus multilocularis dual specificity 0.0156 0.0321 0.0922
Trypanosoma brucei cdc2-related kinase 1 0.0318 0.0899 0.6972
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0162 0.0342 0.098
Onchocerca volvulus Tyrosine kinase homolog 0.0527 0.1646 0.4683
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Giardia lamblia Kinase, CMGC CLK 0.0426 0.1285 1
Schistosoma mansoni serine/threonine protein kinase 0.03 0.0836 0.1976
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1041 0.3484 0.3467
Echinococcus granulosus casein kinase I delta 0.0127 0.0215 0.0617
Plasmodium vivax serine/threonine kinase-1, putative 0.0426 0.1285 1
Brugia malayi Protein kinase domain containing protein 0.0113 0.0168 0.0143
Plasmodium falciparum serine/threonine protein kinase, putative 0.0279 0.0759 0.5868
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.03 0.0836 0.647
Echinococcus granulosus nervana 2 0.0121 0.0195 0.056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0445 0.1352 0.3882
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Brugia malayi serine/threonine protein kinase 6 0.0279 0.0759 0.0735
Onchocerca volvulus 0.0127 0.0215 0.0543
Giardia lamblia Kinase, AGC AKT 0.0135 0.0245 0.1824
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0168 0.0143
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0426 0.1285 0.1262
Trichomonas vaginalis STE family protein kinase 0.0104 0.0136 0.097
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0199 0.0476 0.1366
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0119 0.0188 0.1378
Echinococcus multilocularis ephrin type A receptor 4 A 0.012 0.0192 0.0551
Schistosoma mansoni serine/threonine kinase 0.0232 0.0594 0.1396
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.1008 0.239
Giardia lamblia Kinase, CMGC CK2 0.0118 0.0185 0.1358
Echinococcus multilocularis serine:threonine protein kinase N2 0.0171 0.0373 0.1072
Entamoeba histolytica protein kinase, putative 0.0102 0.0126 0.0366
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0171 0.0373 0.1072
Echinococcus granulosus activin receptor type 0.011 0.0156 0.0447
Trichomonas vaginalis CMGC family protein kinase 0.0348 0.1008 0.7824
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0103 0.0131 0.0933
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0097 0.0109 0.0313
Echinococcus multilocularis expressed protein 0.0102 0.0126 0.0361
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.01 0.012 0.0094
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0373 0.0866
Echinococcus granulosus tyrosine kinase 0.0113 0.0168 0.0483
Echinococcus multilocularis rho associated protein kinase 0.0956 0.3181 0.9129
Brugia malayi Serine/threonine-protein kinase SULU 0.0238 0.0612 0.0587
Loa Loa (eye worm) hypothetical protein 0.0451 0.1376 0.1353
Onchocerca volvulus 0.0348 0.1008 0.2837
Echinococcus multilocularis serine threonine protein kinase 0.0211 0.0516 0.1482
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1041 0.3484 1
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0171 0.0373 0.1072
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0217 0.0537 0.1541
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0607 0.1933 0.1912
Brugia malayi serine/threonine-protein kinase plk-2 0.0285 0.078 0.0756
Echinococcus multilocularis Immunoglobulin 0.008 0.0048 0.0138
Brugia malayi Protein kinase domain containing protein 0.03 0.0837 0.0813
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0173 0.0383 0.2911
Brugia malayi map kinase activated protein kinase protein 2 0.0406 0.1214 0.119
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0426 0.1285 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0292 0.0807 0.2318
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0466 0.143 0.4105
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0424 0.1279 0.1256
Brugia malayi Protein kinase domain containing protein 0.0318 0.0899 0.0876
Echinococcus granulosus protein tyrosine kinase 0.0552 0.1738 0.4988
Echinococcus granulosus protein kinase C gamma type 0.0211 0.0516 0.1482
Loa Loa (eye worm) AGC/AKT protein kinase 0.03 0.0837 0.0813
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0135 0.0245 0.0219
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0936 0.3109 0.3091
Echinococcus multilocularis 0.017 0.037 0.1062
Trichomonas vaginalis AGC family protein kinase 0.03 0.0836 0.647
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0118 0.0186 0.1361
Brugia malayi Protein kinase domain containing protein 0.0171 0.0373 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0221 0.0502
Entamoeba histolytica cell division protein kinase 2, putative 0.0318 0.0899 0.2865
Schistosoma mansoni protein kinase 0.0083 0.006 0.0114
Loa Loa (eye worm) hypothetical protein 0.014 0.0262 0.0236
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0321 0.2426
Brugia malayi Casein kinase II, alpha chain 0.0118 0.0185 0.0159
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0093 0.0093 0.0067
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0466 0.143 0.4105
Loa Loa (eye worm) hypothetical protein 0.0113 0.0168 0.0143
Echinococcus granulosus CDC7 cell division cycle 7 0.0348 0.1008 0.2893
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.078 0.6035
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0128 0.0367
Entamoeba histolytica protein kinase , putative 0.0279 0.0759 0.2411
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0348 0.1009 0.783
Echinococcus granulosus tyrosine protein kinase Fps85D 0.041 0.1229 0.3528
Schistosoma mansoni serine/threonine protein kinase 0.1041 0.3484 0.8335
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0156 0.0321 0.2426
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0173 0.0383 0.1099
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0321 0.0997
Echinococcus multilocularis tyrosine protein kinase Fyn 0.024 0.062 0.1779
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.03 0.0836 0.647
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0153 0.0311 0.2348
Brugia malayi Protein kinase domain containing protein 0.0102 0.0126 0.01
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0128 0.0102
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0486 0.1499 0.1477
Echinococcus granulosus rho-associated protein kinase 1 0.0956 0.3181 0.9129
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0107 0.0081
Brugia malayi hypothetical protein 0.0095 0.0103 0.0077
Leishmania major protein kinase A catalytic subunit 0.03 0.0836 0.647
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Trypanosoma cruzi cdc2-related kinase 3 0.0318 0.0899 0.6972
Loa Loa (eye worm) hypothetical protein 0.0216 0.0535 0.051
Brugia malayi Protein kinase domain containing protein 0.0113 0.0168 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Plasmodium falciparum glycogen synthase kinase 3 0.0348 0.1009 0.783
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.0759 0.2411
Trypanosoma cruzi casein kinase, putative 0.0127 0.0215 0.1593
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0185 0.1358
Schistosoma mansoni tyrosine kinase 0.0322 0.0915 0.2167
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0074 0.0027 0.0117
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0156 0.0321 0.2426
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0215 0.0617
Giardia lamblia Kinase, NEK 0.0153 0.0311 0.2348
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0426 0.1285 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.011 0.0156 0.1127
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0445 0.1352 0.3882
Loa Loa (eye worm) AGC/PKG protein kinase 0.0152 0.0306 0.028
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0307 0.0706
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.03 0.0836 0.647
Echinococcus granulosus protein kinase 0.0424 0.1279 0.3672
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.009 0.0083 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0667 0.1573
Brugia malayi casein kinase I 0.0127 0.0215 0.0189
Mycobacterium ulcerans hypothetical protein 0.0099 0.0118 0.5
Echinococcus multilocularis rac serine:threonine kinase 0.0182 0.0414 0.1189
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0097 0.0109 0.0083
Echinococcus granulosus epidermal growth factor receptor 0.0406 0.1216 0.349
Echinococcus granulosus tyrosine kinase 0.0199 0.0476 0.1366
Echinococcus granulosus tyrosine protein kinase Blk 0.0199 0.0476 0.1366
Loa Loa (eye worm) TK protein kinase 0.0272 0.0736 0.0711
Echinococcus granulosus cGMP dependent protein kinase 0.0152 0.0306 0.0878
Brugia malayi Protein kinase domain containing protein 0.0486 0.1499 0.1477
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0078 0.0042 0.0122
Trypanosoma cruzi p21-activated kinase 3, putative 0.0074 0.0026 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.0103 0.0077
Echinococcus multilocularis dual specificity 0.0156 0.0321 0.0922
Trypanosoma cruzi casein kinase, putative 0.0127 0.0215 0.1593
Schistosoma mansoni serine/threonine protein kinase 0.03 0.0836 0.1976
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0182 0.0414 0.3157
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0079 0.0161
Echinococcus granulosus cyclin dependent kinase 5 0.0318 0.0899 0.2582
Echinococcus multilocularis epidermal growth factor receptor 0.061 0.1944 0.5579
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0128 0.0367
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0279 0.0759 0.2179
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0535 0.4106
Schistosoma mansoni serine/threonine protein kinase 0.0357 0.1038 0.2463
Brugia malayi Egg laying defective protein 4 0.0152 0.0306 0.028
Entamoeba histolytica serine/threonine protein kinase, putative 0.0108 0.0148 0.0437
Brugia malayi Stress-activated protein kinase jnk-1 0.0279 0.0759 0.0735
Loa Loa (eye worm) hypothetical protein 0.0087 0.0075 0.0049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.024 0.062 0.1779
Entamoeba histolytica protein kinase, putative 0.03 0.0837 0.2663
Brugia malayi hypothetical protein 0.0113 0.0168 0.0143
Brugia malayi serine/threonine-protein kinase PAK 7 0.0247 0.0647 0.0622
Loa Loa (eye worm) hypothetical protein 0.03 0.0836 0.0812
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.041 0.1229 0.3528
Trichomonas vaginalis AGC family protein kinase 0.03 0.0837 0.6482
Brugia malayi Protein kinase domain containing protein 0.0426 0.1285 0.1262
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0074 0.0026 0.0108
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0119 0.0188 0.0162
Trypanosoma cruzi casein kinase II, putative 0.0118 0.0185 0.1358
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0083 0.0169
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.03 0.0836 0.2398
Giardia lamblia Kinase, PLK 0.0285 0.078 0.6035
Schistosoma mansoni serine/threonine protein kinase 0.0426 0.1285 0.3054
Loa Loa (eye worm) hypothetical protein 0.0095 0.0103 0.0077
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0078 0.0042 0.0122
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0119 0.0188 0.0162
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0316 0.0894 0.2565
Entamoeba histolytica protein kinase, putative 0.0083 0.006 0.0154
Onchocerca volvulus 0.0113 0.0168 0.0408
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0426 0.1285 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.008 0.0048 0.0138
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0603 0.1919 0.1898
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0156 0.0321 0.2426
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.014 0.0263 0.1966
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.1503 0.3579
Trypanosoma cruzi Protein kinase B 0.0182 0.0414 0.3157
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0263 0.06
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0074 0.0026 0.0108
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0262 0.07 0.2008
Echinococcus multilocularis mitogen activated protein kinase 14 0.0176 0.0392 0.1124
Echinococcus multilocularis cyclin dependent kinase 1 0.0318 0.0899 0.2582
Loa Loa (eye worm) hypothetical protein 0.0087 0.0075 0.0049
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0188 0.0539
Echinococcus granulosus serine:threonine protein kinase Chk2 0.009 0.0083 0.0238
Echinococcus multilocularis tyrosine protein kinase Fyn 0.024 0.062 0.1779
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Schistosoma mansoni hypothetical protein 0.01 0.0119 0.0255
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.0414 0.0964
Echinococcus granulosus insulin receptor 0.0451 0.1375 0.3948
Entamoeba histolytica protein kinase, putative 0.0171 0.0373 0.1165
Schistosoma mansoni protein kinase 0.0486 0.1499 0.3569
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0119 0.0188 0.1378
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0144 0.0277 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.01 0.012 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.009 0.0083 0.0238
Echinococcus granulosus NDR protein kinase 0.0171 0.0373 0.1072
Trichomonas vaginalis CMGC family protein kinase 0.0318 0.0899 0.6972
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0128 0.0907
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0156 0.0321 0.0296
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0285 0.078 0.224
Echinococcus granulosus cyclin dependent kinase 1 0.0318 0.0899 0.2582
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0232 0.059 0.1695
Schistosoma mansoni tyrosine kinase 0.0376 0.1108 0.2631
Brugia malayi Immunoglobulin I-set domain containing protein 0.0603 0.1919 0.1898
Loa Loa (eye worm) hypothetical protein 0.0118 0.0184 0.0158
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0181 0.0409 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0104 0.0136 0.039
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0128 0.0367
Entamoeba histolytica casein kinase 1, putative 0.0127 0.0215 0.0654
Echinococcus multilocularis cyclin dependent kinase 5 0.0318 0.0899 0.2582
Giardia lamblia Kinase, STE STE20 0.0103 0.0131 0.0933
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0102 0.0126 0.01
Brugia malayi Protein kinase domain containing protein 0.0132 0.0234 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0238 0.1769
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0232 0.0594 0.0569
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0148 0.1063
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0128 0.0907
Entamoeba histolytica protein kinase, putative 0.014 0.0263 0.0808
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0426 0.1285 1
Trichomonas vaginalis CMGC family protein kinase 0.0426 0.1285 1
Onchocerca volvulus 0.014 0.0262 0.0679
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0108 0.0148 0.1063
Brugia malayi protein-tyrosine kinase 0.0199 0.0476 0.0451
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0373 0.2837
Brugia malayi phosphoinositide-dependent protein kinase I 0.01 0.012 0.0094
Toxoplasma gondii histone kinase SNF1, putative 0.0108 0.0148 0.1063
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.078 0.6035
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0238 0.0612 0.0587
Schistosoma mansoni protein kinase 0.011 0.0156 0.0344
Loa Loa (eye worm) casein kinase 0.0176 0.0393 0.0368
Echinococcus granulosus tyrosine protein kinase shark 0.0322 0.0915 0.2626
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0348 0.1009 0.783
Brugia malayi Fes/CIP4 homology domain containing protein 0.0114 0.0172 0.0146
Trypanosoma brucei protein kinase, putative 0.0348 0.1009 0.783
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0285 0.078 0.6035
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0152 0.0306 0.2306
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0216 0.0535 0.1535
Onchocerca volvulus 0.0216 0.0535 0.1468
Brugia malayi Protein kinase domain containing protein 0.01 0.012 0.0094
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0181 0.0409 0.1174
Loa Loa (eye worm) hypothetical protein 0.0136 0.0248 0.0222
Brugia malayi intracellular kinase 0.0348 0.1009 0.0985
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0097 0.011 0.0315
Echinococcus multilocularis cyclin dependent kinase 0.0318 0.0899 0.2582
Brugia malayi C1-like domain containing protein 0.0233 0.0596 0.0571
Schistosoma mansoni hypothetical protein 0.01 0.0119 0.0255
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0426 0.1285 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0486 0.1499 0.4303
Echinococcus granulosus protein kinase c epsilon type 0.0213 0.0524 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0321 0.0741
Echinococcus granulosus dual specificity 0.0156 0.0321 0.0922
Entamoeba histolytica PH domain containing protein kinase, putative 0.0309 0.0867 0.2759
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0097 0.0109 0.0313
Echinococcus granulosus c-Jun N-terminal kinases 0.0279 0.0759 0.2179

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Inhibition of mouse 3T3-L1 cell differentiation at 0.2 uM ChEMBL. 17618115

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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