Detailed information for compound 455483

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.483 | Formula: C22H18N6OS
  • H donors: 2 H acceptors: 4 LogP: 2.25 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=c1[nH]ccc(c1c1nc2c([nH]1)cc(cc2C)n1cncc1)SCc1ccccn1
  • InChi: 1S/C22H18N6OS/c1-14-10-16(28-9-8-23-13-28)11-17-20(14)27-21(26-17)19-18(5-7-25-22(19)29)30-12-15-4-2-3-6-24-15/h2-11,13H,12H2,1H3,(H,25,29)(H,26,27)
  • InChiKey: DHGRTSCVOMSWIP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Plasmodium falciparum hexose transporter Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni glucose transport protein Get druggable targets OG5_127135 All targets in OG5_127135
Plasmodium berghei hexose transporter Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus granulosus solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Neospora caninum Glucose transporter 1A, related Get druggable targets OG5_127135 All targets in OG5_127135
Plasmodium falciparum hexose transporter Get druggable targets OG5_127135 All targets in OG5_127135
Plasmodium yoelii putative sugar transporter Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus multilocularis solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma mansoni glucose transport protein Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum Solute carrier family 2, facilitated glucose transporter member 1, putative Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus multilocularis General substrate transporter Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus granulosus solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum Solute carrier family 2, facilitated glucose transporter member 4, putative Get druggable targets OG5_127135 All targets in OG5_127135
Plasmodium knowlesi hexose transporter, putative Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma mansoni hypothetical protein Get druggable targets OG5_127135 All targets in OG5_127135
Brugia malayi Sugar transporter family protein Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma mansoni glucose transport protein Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus multilocularis solute carrier family 2, facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus granulosus General substrate transporter Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum IPR005828,General substrate transporter,domain-containing Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus granulosus solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Candida albicans almost identical to C terminus of CaP19.2425 Get druggable targets OG5_127135 All targets in OG5_127135
Candida albicans C terminus is almost identical to CaP19.2865 Get druggable targets OG5_127135 All targets in OG5_127135
Loa Loa (eye worm) sugar transporter Get druggable targets OG5_127135 All targets in OG5_127135
Candida albicans C terminus is almost identical to CaP19.2865 Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum ko:K07191 MFS transporter, SP family, solute carrier family 2 (facilitated, putative Get druggable targets OG5_127135 All targets in OG5_127135
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum Solute carrier family 2, facilitated glucose transporter member 3, putative Get druggable targets OG5_127135 All targets in OG5_127135
Schistosoma japonicum ko:K07299 MFS transporter, SP family, solute carrier family 2 (facilitated, putative Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus granulosus solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus multilocularis solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Echinococcus multilocularis solute carrier family 2 facilitated glucose Get druggable targets OG5_127135 All targets in OG5_127135
Candida albicans almost identical to C terminus of CaP19.2425 Get druggable targets OG5_127135 All targets in OG5_127135
Toxoplasma gondii facilitative glucose transporter GT1 Get druggable targets OG5_127135 All targets in OG5_127135
Plasmodium vivax hexose transporter Get druggable targets OG5_127135 All targets in OG5_127135
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei glucose transporter, putative hexose transporter 504 aa 426 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni amine GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0267 0.0238
Schistosoma mansoni cript-related 0.0016 0.0088 0.0088
Schistosoma mansoni glucose transport protein 0.006 0.0918 0.0918
Brugia malayi follicle stimulating hormone receptor 0.0321 0.5815 0.5815
Schistosoma mansoni ran 0.0013 0.003 0.003
Schistosoma mansoni amine GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Loa Loa (eye worm) inositol-1 0.0024 0.0248 0.0238
Echinococcus multilocularis neutral alpha glucosidase AB 0.0046 0.0659 0.0659
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.021 0.3737 0.3737
Schistosoma mansoni amine GPCR 0.021 0.3737 0.3737
Loa Loa (eye worm) neuropeptide F receptor 0.021 0.3737 0.373
Schistosoma mansoni synaptojanin 0.0016 0.0088 0.0088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.1407 0.1407
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.3737 0.3737
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Echinococcus multilocularis lysosomal alpha glucosidase 0.0209 0.3705 0.3705
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.0062 0.0946 0.0946
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.017 0.2987 0.298
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0022 0.02 0.0319
Toxoplasma gondii pyruvate kinase PyK1 0.0022 0.0199 0.1036
Onchocerca volvulus Phospholipase A2 homolog 0.0103 0.1714 0.1706
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0473
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0473
Loa Loa (eye worm) hypothetical protein 0.0022 0.0212 0.0202
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0032 0.0387 0.2886
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Echinococcus multilocularis g-protein coupled receptor 0.021 0.3737 0.3737
Brugia malayi steroid hormone receptor 0.0012 0.001 0.001
Onchocerca volvulus Huntingtin homolog 0.017 0.2984 0.2979
Loa Loa (eye worm) G-protein coupled receptor 0.021 0.3737 0.373
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0079 0.1264 0.1264
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0267 0.0238
Echinococcus multilocularis neuropeptides capa receptor 0.021 0.3737 0.3737
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0079 0.1267 0.1267
Mycobacterium tuberculosis Conserved protein 0.0042 0.0579 0.1112
Plasmodium vivax hexose transporter 0.006 0.0918 0.7248
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0079 0.1264 0.1264
Echinococcus multilocularis histone acetyltransferase MYST2 0.003 0.0352 0.0352
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0088 0.0473
Echinococcus multilocularis tachykinin peptides receptor 99D 0.021 0.3737 0.3737
Echinococcus multilocularis tar DNA binding protein 0.0165 0.2879 0.2879
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0046 0.0659 0.0631
Brugia malayi RNA recognition motif domain containing protein 0.0165 0.2879 0.2879
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0079 0.1267 1
Echinococcus multilocularis chromobox protein 1 0.0045 0.0641 0.0641
Loa Loa (eye worm) glutaminase 2 0.018 0.3174 0.3168
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0579 0.1112
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0051 0.005
Echinococcus granulosus inositol monophosphatase 1 0.0024 0.0248 0.0247
Echinococcus multilocularis calpain family protein 1, d 0.0023 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Onchocerca volvulus 0.0026 0.0284 0.0274
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0034 0.0435 0.0435
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 0.1685
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0017 0.0114 0.0679
Brugia malayi exodeoxyribonuclease III family protein 0.0079 0.1267 0.1267
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0058 0.0029
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.021 0.3737 0.3737
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0032 0.0387 0.2886
Loa Loa (eye worm) calpain family protein 1 0.0023 0.0221 0.0211
Echinococcus granulosus zinc finger protein 0.0036 0.0471 0.0471
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0088 0.0088
Mycobacterium ulcerans bacterioferritin BfrB 0.008 0.1288 0.3968
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.1267 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0016 0.0083 0.0429
Onchocerca volvulus 0.021 0.3737 0.3732
Onchocerca volvulus 0.0048 0.0699 0.069
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0579 0.4438
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.001 0.001
Loa Loa (eye worm) glutathione reductase 0.0023 0.0226 0.0216
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.001 0.001
Brugia malayi Muscleblind-like protein 0.0344 0.6232 0.6232
Loa Loa (eye worm) hypothetical protein 0.002 0.0164 0.0154
Schistosoma mansoni lamin 0.0048 0.0699 0.0698
Plasmodium falciparum pyruvate kinase 0.0022 0.0199 0.1571
Brugia malayi beta-lactamase family protein 0.0042 0.0579 0.0579
Echinococcus granulosus geminin 0.0495 0.9067 0.9067
Schistosoma mansoni hypothetical protein 0.0116 0.1964 0.1964
Schistosoma mansoni chromobox protein 0.0045 0.0641 0.0641
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.1921 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.0098 0.1637 0.1628
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.001 0.001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0046 0.0659 0.5086
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0088 0.0473
Leishmania major DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.001 0.001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0014 0.006 0.0476
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0579 0.1699
Echinococcus granulosus biogenic amine 5HT receptor 0.021 0.3737 0.3737
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0034 0.0435 0.0435
Brugia malayi CCR4 0.0016 0.0088 0.0088
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0053 0.0784 0.154
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0659 0.0631
Brugia malayi hypothetical protein 0.0062 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0189
Echinococcus granulosus fmrfamide receptor 0.021 0.3737 0.3737
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0025 0.0251 0.1786
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0042 0.0574 0.0574
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0086 0.1407 0.1407
Trichomonas vaginalis glucosylceramidase, putative 0.0118 0.2001 0.1978
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0029 0.0331 0.033
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0088 0.0473
Trichomonas vaginalis DNA polymerase eta, putative 0.0016 0.0083 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Loa Loa (eye worm) runx1 0.0057 0.0867 0.0858
Echinococcus granulosus somatostatin receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0025 0.0267 0.0257
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0303 0.0275
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0013 0.003 0.0235
Echinococcus multilocularis biogenic amine (5HT) receptor 0.021 0.3737 0.3737
Trichomonas vaginalis pyruvate kinase, putative 0.0022 0.0199 0.017
Echinococcus granulosus neuropeptide receptor A26 0.0444 0.8116 0.8116
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0025 0.0251 0.0241
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.1097 0.1097
Brugia malayi Dopamine receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0017 0.0116 0.0106
Echinococcus granulosus g protein coupled receptor 0.021 0.3737 0.3737
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0088 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0072 0.1138 0.1129
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0659 0.0631
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Loa Loa (eye worm) hypothetical protein 0.005 0.0735 0.0725
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.3737 0.3737
Echinococcus multilocularis orexin receptor type 2 0.021 0.3737 0.3737
Schistosoma mansoni inositol monophosphatase 0.0024 0.0248 0.0247
Brugia malayi G protein-coupled receptor F59B2.13 0.021 0.3737 0.3737
Schistosoma mansoni cpg binding protein 0.0063 0.0971 0.0971
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0036 0.047 0.047
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.008 0.1288 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Brugia malayi Dopamine receptor protein 1 0.021 0.3737 0.3737
Schistosoma mansoni bromodomain containing protein 0.011 0.1855 0.1855
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0088 0.0473
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0579 0.0569
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0088 0.0697
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0083 0.0083
Echinococcus granulosus peptide allatostatin:somatostatin 0.021 0.3737 0.3737
Brugia malayi Pyruvate kinase, muscle isozyme 0.0022 0.0199 0.0199
Onchocerca volvulus 0.0077 0.1236 0.1228
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0023 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0054 0.0796 0.0796
Onchocerca volvulus Neuropeptide F receptor homolog 0.021 0.3737 0.3732
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0088 0.0473
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Echinococcus granulosus lamin 0.0048 0.0699 0.0698
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.3737 0.3737
Echinococcus multilocularis lamin 0.0048 0.0699 0.0698
Echinococcus multilocularis acetylcholinesterase 0.0025 0.0266 0.0266
Onchocerca volvulus 0.0544 0.9995 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0088 0.0697
Loa Loa (eye worm) hypothetical protein 0.0048 0.0699 0.0689
Loa Loa (eye worm) hypothetical protein 0.017 0.2984 0.2977
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.003 0.0352 0.0352
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0579 0.0579
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Loa Loa (eye worm) hypothetical protein 0.0014 0.0047 0.0037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.1639 0.1639
Loa Loa (eye worm) carboxylesterase 0.0025 0.0266 0.0256
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0016 0.0083 0.0074
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0331 0.033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0579 0.0579
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.021 0.3737 0.3737
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0059 0.0895 0.6827
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.017 0.2987 0.2987
Plasmodium vivax thioredoxin reductase, putative 0.0023 0.0226 0.1782
Trichomonas vaginalis importin beta-1, putative 0.0014 0.0054 0.0024
Brugia malayi PHD-finger family protein 0.0045 0.064 0.064
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0059 0.0895 0.1772
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0088 0.0088
Echinococcus granulosus hypothetical protein 0.021 0.3737 0.3737
Echinococcus granulosus peptidase Clp S14 family 0.0027 0.0304 0.0304
Schistosoma mansoni pyruvate kinase 0.0022 0.0199 0.0199
Brugia malayi larval opioid receptor 0.021 0.3737 0.3737
Entamoeba histolytica hypothetical protein 0.0062 0.0946 0.7409
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0214 0.0214
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.001 0.001
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0088 0.0473
Schistosoma mansoni ap endonuclease 0.0079 0.1267 0.1267
Brugia malayi intermediate filament protein 0.0048 0.0699 0.0699
Schistosoma mansoni ferritin light chain 0.008 0.1288 0.1288
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0042 0.0574 0.2989
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0248 0.176
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Echinococcus multilocularis fmrfamide receptor 0.021 0.3737 0.3737
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.001 0.001
Trichomonas vaginalis glutaminase, putative 0.018 0.3174 0.3156
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0088 0.0059
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.021 0.3737 0.3732
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0088 0.0088
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Echinococcus granulosus pyruvate kinase 0.0022 0.0199 0.0199
Echinococcus multilocularis muscleblind protein 0.0344 0.6232 0.6232
Loa Loa (eye worm) neuropeptide F receptor 0.021 0.3737 0.373
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0544 1 1
Mycobacterium leprae Probable lipase LipE 0.0042 0.0579 0.4283
Trypanosoma brucei protein kinase, putative 0.0025 0.0251 0.1786
Echinococcus multilocularis geminin 0.0495 0.9067 0.9067
Toxoplasma gondii exonuclease III APE 0.0079 0.1267 0.6594
Brugia malayi Tachykinin-like peptides receptor 99D 0.021 0.3737 0.3737
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0047 0.0141
Entamoeba histolytica hypothetical protein 0.0062 0.0946 0.7409
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0089 0.1468 0.1468
Entamoeba histolytica hypothetical protein 0.0062 0.0946 0.7409
Schistosoma mansoni inositol monophosphatase 0.0024 0.0248 0.0247
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0013 0.003 0.002
Brugia malayi CHD4 protein 0.0014 0.0051 0.0051
Echinococcus granulosus expressed protein 0.008 0.1288 0.1288
Entamoeba histolytica hypothetical protein 0.0062 0.0946 0.7409
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0088 0.0473
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.021 0.3737 0.3737
Echinococcus granulosus neuropeptides capa receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0579 0.1112
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0101 0.0101
Schistosoma mansoni opsin-like receptor 0.021 0.3737 0.3737
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0025 0.0251 0.1786
Schistosoma mansoni ferritin light chain 0.008 0.1288 0.1288
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.001 0.001
Giardia lamblia Kinase, CMGC MAPK 0.0025 0.0251 0.1707
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.021 0.3737 0.3737
Echinococcus granulosus 7tm_1 domain containing protein 0.021 0.3737 0.3737
Echinococcus multilocularis somatostatin receptor 0.021 0.3737 0.3737
Mycobacterium tuberculosis Probable oxidoreductase 0.0059 0.0895 0.1772
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.021 0.3737 0.3737
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.021 0.3737 0.3737
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0918 0.0891
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 0.1685
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Echinococcus multilocularis synaptojanin 1 0.0016 0.0088 0.0088
Schistosoma mansoni peptide (allatostatin)-like receptor 0.021 0.3737 0.3737
Brugia malayi G-protein coupled receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0026 0.0284 0.0274
Loa Loa (eye worm) RNA binding protein 0.0165 0.2879 0.2872
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.021 0.3737 0.3737
Loa Loa (eye worm) transcription factor SMAD2 0.0072 0.1138 0.1129
Schistosoma mansoni hypothetical protein 0.0035 0.0444 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Trichomonas vaginalis pyruvate kinase, putative 0.0022 0.0199 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Schistosoma mansoni DNA polymerase eta 0.0016 0.0083 0.0083
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0088 0.0697
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0054 0.0796 0.0796
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0053 0.0784 0.154
Schistosoma mansoni importin beta-1 0.0017 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0083 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0251 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0579 0.4438
Echinococcus multilocularis fmrfamide receptor 0.021 0.3737 0.3737
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0114 0.0084
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0062 0.0946 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Echinococcus granulosus tachykinin peptides receptor 99D 0.021 0.3737 0.3737
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0928 0.0928
Brugia malayi G protein-coupled receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis alpha 1A adrenergic receptor 0.021 0.3737 0.3737
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.021 0.3737 0.3737
Schistosoma mansoni tar DNA-binding protein 0.0165 0.2879 0.2879
Schistosoma mansoni myosin xvIII 0.021 0.3737 0.3737
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0025 0.0251 0.1786
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0104 0.1742 0.1742
Toxoplasma gondii facilitative glucose transporter GT1 0.006 0.0918 0.478
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0088 0.0059
Leishmania major pyruvate kinase 0.0022 0.0199 0.1368
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0088 0.0059
Onchocerca volvulus 0.0057 0.085 0.0842
Brugia malayi MH2 domain containing protein 0.0072 0.1138 0.1138
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.021 0.3737 0.373
Schistosoma mansoni neuropeptide F-like receptor 0.021 0.3737 0.3737
Echinococcus granulosus intermediate filament protein 0.0048 0.0699 0.0698
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0024 0.0248 0.176
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0099 0.0558
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0013 0.003 0.003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.1407 0.1407
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.0083 0.0073
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Onchocerca volvulus Huntingtin homolog 0.017 0.2984 0.2979
Echinococcus multilocularis zinc finger protein 0.0036 0.0471 0.0471
Schistosoma mansoni hypothetical protein 0.0054 0.0796 0.0796
Schistosoma mansoni cpg binding protein 0.0063 0.0971 0.0971
Plasmodium vivax pyruvate kinase, putative 0.0022 0.0199 0.1571
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.1637 0.1637
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0199 0.0189
Brugia malayi hypothetical protein 0.0483 0.8852 0.8852
Schistosoma mansoni thyroid hormone receptor 0.0012 0.001 0.001
Schistosoma mansoni growth hormone secretagogue receptor 0.021 0.3737 0.3737
Schistosoma mansoni alpha-glucosidase 0.018 0.316 0.316
Schistosoma mansoni adenoreceptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.017 0.297 0.2963
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0013 0.003 0.003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0025 0.0251 0.1786
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.021 0.3737 0.3737
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.3737 0.3737
Schistosoma mansoni neuropeptide receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0248 0.176
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0088 0.0473
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0659 0.5086
Echinococcus granulosus neuropeptide receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.0078
Echinococcus multilocularis snurportin 1 0.0185 0.3265 0.3265
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.021 0.3737 0.3737
Onchocerca volvulus 0.0016 0.0088 0.0078
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0579 0.1112
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Schistosoma mansoni neuropeptide receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) pigment dispersing factor receptor c 0.017 0.297 0.2963
Echinococcus multilocularis thioredoxin glutathione reductase 0.0024 0.0232 0.0232
Echinococcus granulosus methyl CpG binding domain protein 2 0.0029 0.0331 0.033
Echinococcus granulosus carboxylesterase 5A 0.0025 0.0266 0.0266
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.001 0.001
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0579 0.1112
Brugia malayi Carboxylesterase family protein 0.0025 0.0266 0.0266
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.001 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0579 0.1112
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.021 0.3737 0.3737
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0041 0.0565 0.0565
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0025 0.0251 0.1786
Schistosoma mansoni ferritin 0.008 0.1288 0.1288
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0199 0.0189
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.003 0.0352 0.0352
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0079 0.1264 0.1255
Schistosoma mansoni opsin-like receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) intermediate filament protein 0.0048 0.0699 0.0689
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.001 0.001
Echinococcus granulosus dna polymerase kappa 0.0016 0.0083 0.0083
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0114 0.0084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0047 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0579 0.1112
Echinococcus granulosus survival motor neuron protein 1 0.0483 0.8852 0.8852
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.0226 0.1584
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Echinococcus granulosus neuropeptide Y receptor 0.021 0.3737 0.3737
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0735 0.5799
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0114 0.0084
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0088 0.0078
Echinococcus multilocularis pyruvate kinase 0.0022 0.0199 0.0199
Brugia malayi Serotonin/octopamine receptor family protein 7 0.021 0.3737 0.3737
Echinococcus granulosus serotonin receptor 0.021 0.3737 0.3737
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0054 0.0024
Brugia malayi neuropeptide F receptor 0.021 0.3737 0.3737
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Trypanosoma brucei pyruvate kinase 1, putative 0.0022 0.0199 0.1368
Trypanosoma brucei DNA polymerase eta, putative 0.0016 0.0083 0.0429
Loa Loa (eye worm) hypothetical protein 0.0089 0.1468 0.146
Trypanosoma cruzi pyruvate kinase 2, putative 0.0022 0.0199 0.1368
Treponema pallidum bacterioferrin (TpF1) 0.008 0.1288 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0027 0.0304 0.2069
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.0083 0.0114
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0544 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0659 0.0631
Brugia malayi Pyruvate kinase, M2 isozyme 0.0022 0.0199 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.001 0.001
Trichomonas vaginalis set domain proteins, putative 0.0544 0.9995 1
Brugia malayi Pre-SET motif family protein 0.007 0.1097 0.1097
Echinococcus multilocularis muscleblind protein 1 0.0344 0.6232 0.6232
Schistosoma mansoni sex comb on midleg homolog 0.0026 0.0284 0.0283
Schistosoma mansoni lozenge 0.0057 0.0867 0.0867
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0199 0.0189
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0444 0.0434
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0079 0.1267 0.2551
Brugia malayi gonadotropin-releasing hormone receptor 2 0.021 0.3737 0.3737
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.021 0.3737 0.3737
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.001 0.001
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.021 0.3737 0.3737
Brugia malayi GnHR receptor homolog 0.021 0.3737 0.3737
Schistosoma mansoni microtubule-associated protein tau 0.0456 0.8333 0.8333
Onchocerca volvulus 0.021 0.3737 0.3732
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Echinococcus multilocularis calpain A 0.0034 0.0435 0.0435
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0641 0.0613
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.012 0.2032 0.2032
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0735 0.5799
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0079 0.1267 0.1258
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0473
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0036 0.047 0.3558
Loa Loa (eye worm) hypothetical protein 0.0025 0.0266 0.0256
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0104
Brugia malayi Pre-SET motif family protein 0.0478 0.8759 0.8759
Echinococcus granulosus pyruvate kinase 0.0022 0.0199 0.0199
Brugia malayi AKH receptor 0.021 0.3737 0.3737
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0027 0.0304 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0444 0.8116 0.8116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0041 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0022 0.02 0.1227
Schistosoma mansoni ferritin 0.008 0.1288 0.1288
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0088 0.0473
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0046 0.0659 0.065
Loa Loa (eye worm) hypothetical protein 0.0025 0.0266 0.0256
Brugia malayi neuropeptide F receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.001 0.001
Plasmodium falciparum hexose transporter 0.006 0.0918 0.7248
Trichomonas vaginalis maltase-glucoamylase, putative 0.0046 0.0659 0.0631
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.021 0.3737 0.373
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.001 0.001
Trypanosoma brucei ISWI complex protein 0.0026 0.0275 0.1981
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.1267 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0013 0.003 0.0235
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.021 0.3737 0.3737
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0088 0.0059
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Echinococcus multilocularis g protein coupled receptor 0.021 0.3737 0.3737
Mycobacterium tuberculosis Conserved protein 0.0042 0.0579 0.1112
Schistosoma mansoni hypothetical protein 0.0544 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0579 0.0551
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Echinococcus multilocularis expressed protein 0.008 0.1288 0.1288
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.0083 0.0083
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0088 0.0473
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0025 0.0267 0.0258
Loa Loa (eye worm) hypothetical protein 0.0483 0.8852 0.8851
Echinococcus multilocularis allatostatin A receptor 0.021 0.3737 0.3737
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0735 0.5698
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Schistosoma mansoni hypothetical protein 0.0023 0.0214 0.0214
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0069 0.1081 0.1072
Echinococcus multilocularis GPCR, family 2 0.0054 0.0796 0.0796
Echinococcus granulosus mitogen activated protein kinase 0.0025 0.0251 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0058 0.0029
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0199 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.001 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0088 0.0473
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0116 0.0695
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.017 0.2984 0.2977
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0579 0.4569
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0026 0.0284 0.0283
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0735 0.3824
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Echinococcus multilocularis lamin dm0 0.0048 0.0699 0.0698
Loa Loa (eye worm) mbt repeat family protein 0.0026 0.0284 0.0274
Echinococcus multilocularis SAM and MBT domain containing protein 0.0026 0.0284 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0659 0.5086
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0088 0.0059
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0053 0.0784 0.5934
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0735 0.5799
Onchocerca volvulus 0.021 0.3737 0.3732
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.0083 0.0083
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0166 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.1407 0.1407
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0051 0.005
Onchocerca volvulus 0.021 0.3737 0.3732
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0089 0.1468 1
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0251 0.0222
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.047 0.1351
Schistosoma mansoni coup transcription factor 0.0012 0.001 0.001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0017 0.0114 0.0084
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.021 0.3737 0.3737
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0079 0.1267 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0046 0.0659 0.0659
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0101 0.0101
Trichomonas vaginalis esterase, putative 0.0042 0.0579 0.0551
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0101 0.0101
Schistosoma mansoni ran 0.0013 0.003 0.003
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.1407 0.1407
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.001 0.001
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 0.3138
Brugia malayi beta-lactamase 0.0042 0.0579 0.0579
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0025 0.0251 0.1305
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.008 0.1288 0.2596
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0088 0.0059
Schistosoma mansoni hypothetical protein 0.0544 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0248 0.176
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.001 0.001
Trichomonas vaginalis ferritin, putative 0.008 0.1288 0.1263
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.047 0.047
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0104 0.1742 0.1742
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0579 0.0551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 0.4532
Loa Loa (eye worm) sugar transporter 0.006 0.0918 0.0909
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0083 0.0429
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0088 0.0078
Schistosoma mansoni nocturnin 0.0016 0.0088 0.0088
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0088 0.0473
Brugia malayi Calcitonin receptor-like protein seb-1 0.017 0.297 0.297
Loa Loa (eye worm) hypothetical protein 0.0065 0.1006 0.0997
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0088 0.0473
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0033 0.0404 0.0403
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.021 0.3737 0.3737
Trichomonas vaginalis sucrase-isomaltase, putative 0.0046 0.0659 0.0631
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.001 0.001
Onchocerca volvulus 0.021 0.3737 0.3732
Echinococcus multilocularis neuropeptide Y receptor 0.021 0.3737 0.3737
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.001 0.001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0059 0.0895 0.1772
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Brugia malayi nuclear hormone receptor 0.0012 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0088 0.0697
Echinococcus multilocularis acetylcholinesterase 0.0025 0.0266 0.0266
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0048 0.0699 0.0689
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0579 0.1699
Echinococcus multilocularis neuropeptide receptor A26 0.0444 0.8116 0.8116
Plasmodium falciparum glutathione reductase 0.0023 0.0226 0.1782
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0065
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.001 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0054 0.0796 0.0796
Echinococcus multilocularis dro:myosuppressin receptor 0.021 0.3737 0.3737
Onchocerca volvulus 0.002 0.0164 0.0154
Echinococcus multilocularis pyruvate kinase 0.0017 0.0113 0.0113
Onchocerca volvulus Glucosylceramidase homolog 0.0112 0.1888 0.1881
Schistosoma mansoni hypothetical protein 0.021 0.3737 0.3737
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.001 0.001
Brugia malayi Melatonin receptor type 1A 0.021 0.3737 0.3737
Brugia malayi Dopamine receptor protein 2 0.021 0.3737 0.3737
Echinococcus multilocularis mitogen activated protein kinase 3 0.0025 0.0251 0.0251
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Brugia malayi Inositol-1 0.0024 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0116 0.0695
Onchocerca volvulus 0.0042 0.0579 0.057
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0083 0.0083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0478 0.8759 0.8758
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Echinococcus granulosus G protein coupled receptor 139 0.021 0.3737 0.3737
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0088 0.0473
Echinococcus multilocularis dnaJ subfamily B 0.0268 0.482 0.482
Loa Loa (eye worm) TYRA-2 protein 0.021 0.3737 0.373
Schistosoma mansoni cpg binding protein 0.0057 0.085 0.085
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus neuropeptide receptor 0.021 0.3737 0.3737
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0088 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0165 0.2879 0.2879
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.001 0.001
Echinococcus granulosus calpain A 0.0034 0.0435 0.0435
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0032 0.0387 0.0387
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0579 0.0579
Onchocerca volvulus 0.021 0.3737 0.3732
Brugia malayi RE15519p 0.021 0.3737 0.3737
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.008 0.1288 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.3737 0.3737
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0269 0.4828 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0027 0.0304 0.0304
Toxoplasma gondii hypothetical protein 0.0014 0.006 0.0314
Schistosoma mansoni apoferritin-2 0.008 0.1288 0.1288
Schistosoma mansoni alpha-glucosidase 0.018 0.316 0.316
Schistosoma mansoni hypothetical protein 0.006 0.0918 0.0918
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.021 0.3737 0.3737
Echinococcus granulosus lysosomal alpha glucosidase 0.0209 0.3705 0.3705
Schistosoma mansoni pyruvate kinase 0.0022 0.0199 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0128 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0659 0.0631
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.0083 0.0114
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0047 0.0047
Brugia malayi putative neuropeptide receptor 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.0054 0.0796 0.0796
Echinococcus granulosus acetylcholinesterase 0.0025 0.0266 0.0266
Brugia malayi Heterochromatin protein 1 0.0045 0.0641 0.0641
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0014 0.006 0.0476
Echinococcus granulosus snurportin 1 0.0185 0.3265 0.3265
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0013 0.003 0.0155
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0079 0.1267 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Echinococcus multilocularis cpg binding protein 0.0063 0.0971 0.0971
Echinococcus multilocularis g protein coupled receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0119 0.203 0.2022
Loa Loa (eye worm) hypothetical protein 0.0075 0.1202 0.1193
Schistosoma mansoni ferritin 0.008 0.1288 0.1288
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0088 0.0697
Loa Loa (eye worm) hypothetical protein 0.0344 0.6232 0.6228
Brugia malayi Sugar transporter family protein 0.006 0.0918 0.0918
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Brugia malayi mbt repeat family protein 0.0026 0.0284 0.0284
Brugia malayi chromobox protein homolog 3 0.0025 0.0267 0.0267
Echinococcus granulosus g protein coupled receptor 0.021 0.3737 0.3737
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.001 0.001
Loa Loa (eye worm) heterochromatin protein 1 0.0045 0.0641 0.0632
Loa Loa (eye worm) TAR-binding protein 0.0165 0.2879 0.2872
Echinococcus granulosus chromobox protein 1 0.0045 0.0641 0.0641
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.3737 0.3737
Schistosoma mansoni ferritin 0.008 0.1288 0.1288
Leishmania major DNA polymerase eta, putative 0.0016 0.0083 0.0429
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0099 0.0558
Echinococcus multilocularis neuropeptide receptor 0.021 0.3737 0.3737
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0088 0.0473
Entamoeba histolytica acyl-coA synthetase, putative 0.0014 0.0047 0.0141
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0086 0.1407 0.1398
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.1407 0.1407
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.1407 0.1407
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0027 0.0304 0.0537
Echinococcus multilocularis importin subunit beta 1 0.0017 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0047 0.0037
Schistosoma mansoni biogenic amine receptor 0.021 0.3737 0.3737
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0114 0.0084
Echinococcus multilocularis pyruvate kinase 0.0022 0.0199 0.0199
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0047 0.0141
Schistosoma mansoni hypothetical protein 0.021 0.3737 0.3737
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0025 0.0251 0.1786
Echinococcus granulosus tar DNA binding protein 0.0165 0.2879 0.2879
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0042 0.0574 0.0574
Echinococcus granulosus allatostatin A receptor 0.021 0.3737 0.3737
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0077 0.1236 0.1236
Trypanosoma brucei trypanothione reductase 0.0023 0.0226 0.1584
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0032 0.0387 0.0387
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Schistosoma mansoni apoferritin-2 0.008 0.1288 0.1288
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0079 0.1264 0.1264
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0088 0.0059
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0027 0.0303 0.0294
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0165 0.2879 0.2872
Echinococcus granulosus 7TM GPCR rhodopsin 0.021 0.3737 0.3737
Echinococcus granulosus thioredoxin glutathione reductase 0.0024 0.0232 0.0232
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0088 0.0088
Loa Loa (eye worm) bromodomain containing protein 0.003 0.035 0.034
Brugia malayi glutaminase DH11.1 0.018 0.3174 0.3174
Loa Loa (eye worm) hypothetical protein 0.0054 0.0796 0.0787
Treponema pallidum exodeoxyribonuclease (exoA) 0.0079 0.1267 0.9824
Leishmania major glycosyl hydrolase-like protein 0.0017 0.0114 0.0679
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.007 0.1097 0.1097
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0024 0.0248 0.064
Onchocerca volvulus 0.021 0.3737 0.3732
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0088 0.0473
Echinococcus granulosus polycomb protein SCMH1 0.0026 0.0284 0.0283
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0101 0.0101
Echinococcus multilocularis G protein coupled receptor 139 0.021 0.3737 0.3737
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.001 0.001
Brugia malayi nuclear receptor NHR-88 0.0012 0.001 0.001
Giardia lamblia hypothetical protein 0.0016 0.0088 0.0601
Loa Loa (eye worm) hypothetical protein 0.0458 0.8373 0.8371
Mycobacterium tuberculosis Conserved protein 0.0042 0.0579 0.1112
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0022 0.0199 0.0317
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.021 0.3737 0.3737
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Schistosoma mansoni peptidase Clp (S14 family) 0.0042 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.001 0.001
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0579 0.4283
Mycobacterium ulcerans pyruvate kinase 0.0022 0.0199 0.0485
Echinococcus multilocularis serotonin receptor 0.021 0.3737 0.3737
Echinococcus granulosus endonuclease exonuclease phosphatase 0.012 0.2032 0.2032
Entamoeba histolytica pyruvate kinase, putative 0.0015 0.0075 0.0368
Brugia malayi hypothetical protein 0.017 0.2984 0.2984
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0222 0.0222
Echinococcus granulosus dnaJ subfamily B 0.0268 0.482 0.482
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0088 0.0088
Brugia malayi glutathione reductase 0.0023 0.0226 0.0226
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0042 0.0574 0.2989
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0331 0.033
Mycobacterium ulcerans glutaminase 0.018 0.3174 1
Echinococcus multilocularis musashi 0.0048 0.0699 0.0698
Mycobacterium ulcerans beta-lactamase 0.0042 0.0579 0.1699
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0199 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0016 0.0083 0.0053
Onchocerca volvulus 0.021 0.3737 0.3732
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Echinococcus granulosus acetylcholinesterase 0.0025 0.0266 0.0266
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.001 0.001
Brugia malayi G-protein coupled receptor 0.021 0.3737 0.3737
Brugia malayi Bromodomain containing protein 0.0065 0.1003 0.1003
Echinococcus granulosus dro:myosuppressin receptor 0.021 0.3737 0.3737
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0088 0.0473
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0088 0.0473
Loa Loa (eye worm) histone methyltransferase 0.002 0.0166 0.0156
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus fetal alzheimer antigen falz 0.0041 0.0565 0.0565
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.0083 0.0429
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.001 0.001
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0303 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0579 0.4438
Loa Loa (eye worm) hypothetical protein 0.0023 0.0221 0.0211
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.0078
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 0.4184
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0166 0.0165
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0387 0.2886
Giardia lamblia DINP protein human, muc B family 0.0016 0.0083 0.0564
Brugia malayi calpain family protein 1 0.0033 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Schistosoma mansoni alpha-1 adrenergic receptor 0.021 0.3737 0.3737
Echinococcus multilocularis ferritin 0.008 0.1288 0.1288
Brugia malayi latrophilin 2 splice variant baaae 0.0116 0.1964 0.1964
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0424 0.0415
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.021 0.3737 0.373
Onchocerca volvulus 0.021 0.3737 0.3732
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0579 0.0579
Brugia malayi RNA, U transporter 1 0.0049 0.0716 0.0716
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0051 0.005
Brugia malayi sulfakinin receptor protein 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0033 0.0404 0.0394
Schistosoma mansoni opsin-like receptor 0.021 0.3737 0.3737
Trypanosoma cruzi ISWI complex protein 0.0026 0.0275 0.1981
Giardia lamblia Inositol 5-phosphatase 4 0.0016 0.0088 0.0601
Trypanosoma brucei glycosyl hydrolase-like protein 0.0017 0.0114 0.0679
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0579 0.0551
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0079 0.1267 1
Leishmania major hypothetical protein, conserved 0.005 0.0735 0.5698
Echinococcus granulosus g protein coupled receptor 0.021 0.3737 0.3737
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.0083 0.0083
Echinococcus granulosus histone acetyltransferase MYST2 0.003 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0033 0.0404 0.0394
Loa Loa (eye worm) calpain family protein 1 0.0033 0.0404 0.0394
Onchocerca volvulus 0.0048 0.0699 0.069
Schistosoma mansoni hypothetical protein 0.0054 0.0796 0.0796
Schistosoma mansoni glucose transport protein 0.006 0.0918 0.0918
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0088 0.0697
Schistosoma mansoni alpha glucosidase 0.0046 0.0659 0.0659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0128 0.0098
Schistosoma mansoni amine GPCR 0.021 0.3737 0.3737
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0047 0.0141
Echinococcus multilocularis neuropeptide FF receptor 2 0.021 0.3737 0.3737
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0088 0.0473
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0321 0.5815 0.5811
Onchocerca volvulus 0.021 0.3737 0.3732
Brugia malayi Carboxylesterase family protein 0.0025 0.0266 0.0266
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0579 0.0551
Echinococcus granulosus General substrate transporter 0.0054 0.0807 0.0807
Trypanosoma cruzi importin beta-1 subunit, putative 0.0014 0.0054 0.0197
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0266 0.0266
Brugia malayi CXXC zinc finger family protein 0.0057 0.085 0.085
Echinococcus granulosus orexin receptor type 2 0.021 0.3737 0.3737
Brugia malayi Thioredoxin reductase 0.0023 0.0226 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0165 0.2879 0.2879
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.003 0.0352 0.0342
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0114 0.0679
Schistosoma mansoni tar DNA-binding protein 0.0165 0.2879 0.2879
Echinococcus granulosus cpg binding protein 0.0063 0.0971 0.0971
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Mycobacterium tuberculosis Bacterioferritin BfrB 0.008 0.1288 0.2596
Schistosoma mansoni lamin 0.0048 0.0699 0.0698
Echinococcus granulosus sex peptide receptor 0.021 0.3737 0.3737
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 1
Plasmodium vivax importin-beta 2, putative 0.0017 0.0116 0.0914
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Leishmania major hypothetical protein, conserved 0.0042 0.0579 0.4438
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0046 0.0659 0.343
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0088 0.0059
Schistosoma mansoni neuropeptide receptor 0.021 0.3737 0.3737
Echinococcus granulosus GPCR family 2 0.0054 0.0796 0.0796
Trypanosoma cruzi ISWI complex protein 0.0026 0.0275 0.1981
Onchocerca volvulus 0.0042 0.0579 0.057
Brugia malayi Probable ClpP-like protease 0.0042 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.001 0.001
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0579 0.0579
Loa Loa (eye worm) latrophilin receptor protein 2 0.0054 0.0796 0.0787
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Trichomonas vaginalis glucosylceramidase, putative 0.0118 0.2001 0.1978
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.001 0.001
Mycobacterium ulcerans lipase LipD 0.0042 0.0579 0.1699
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0248 0.0218
Onchocerca volvulus 0.0016 0.0088 0.0078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0212 0.0202
Brugia malayi Glycosyl hydrolases family 31 protein 0.0017 0.0114 0.0114
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0017 0.0114 0.0679
Onchocerca volvulus 0.021 0.3737 0.3732
Leishmania major pyruvate kinase 0.0022 0.0199 0.1368
Onchocerca volvulus 0.0042 0.0579 0.057
Echinococcus granulosus lamin dm0 0.0048 0.0699 0.0698
Echinococcus multilocularis neuropeptide Y receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0185 0.3265 0.3258
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0051 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0088 0.0059
Loa Loa (eye worm) hypothetical protein 0.0048 0.0682 0.0673
Loa Loa (eye worm) hypothetical protein 0.0023 0.0229 0.0219
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0016 0.0083 0.0429
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0026 0.0277 0.0267
Echinococcus multilocularis dna polymerase eta 0.0016 0.0083 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0251 0.0222
Echinococcus granulosus ferritin 0.008 0.1288 0.1288
Schistosoma mansoni glucose transport protein 0.006 0.0918 0.0918
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0088 0.0088
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0088 0.0697
Plasmodium falciparum importin beta, putative 0.0017 0.0116 0.0914
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0013 0.003 0.0203
Echinococcus multilocularis g protein coupled receptor 0.021 0.3737 0.3737
Brugia malayi calpain family protein 1 0.0033 0.0404 0.0404
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0042 0.0574 0.4532
Echinococcus granulosus GTP binding nuclear protein Ran 0.0013 0.003 0.003
Onchocerca volvulus 0.0458 0.8373 0.8375
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0079 0.1267 0.3899
Echinococcus multilocularis dna polymerase kappa 0.0016 0.0083 0.0083
Echinococcus multilocularis mitogen activated protein kinase 0.0025 0.0251 0.0251
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.047 0.0884
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0032 0.0387 0.0387
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.1407 0.1407
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0047 0.0141
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0041 0.0565 0.0565
Loa Loa (eye worm) melatonin receptor type 1A 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0579 0.1112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Loa Loa (eye worm) hypothetical protein 0.0458 0.8373 0.8371
Schistosoma mansoni survival motor neuron protein 0.0099 0.1639 0.1639
Mycobacterium ulcerans bacterioferritin BfrA 0.008 0.1288 0.3968
Loa Loa (eye worm) hypothetical protein 0.0116 0.1964 0.1956
Brugia malayi Serotonin receptor 0.021 0.3737 0.3737
Echinococcus multilocularis carboxylesterase 5A 0.0025 0.0266 0.0266
Onchocerca volvulus 0.0121 0.2054 0.2047
Echinococcus multilocularis neuropeptide receptor 0.021 0.3737 0.3737
Trypanosoma brucei pyruvate kinase 1 0.0022 0.0199 0.1368
Echinococcus granulosus microtubule associated protein 2 0.0456 0.8333 0.8333
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0101 0.0101
Brugia malayi putative neuropeptide receptor NPR1 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0103 0.1714 0.1705
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus FTZ F1 alpha 0.0012 0.001 0.001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.001 0.001
Loa Loa (eye worm) pyruvate kinase-PB 0.0015 0.0075 0.0065
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0025 0.0251 0.1786
Brugia malayi hypothetical protein 0.0033 0.04 0.04
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.1267 0.1241
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0083 0.0429
Schistosoma mansoni biogenic amine (5HT) receptor 0.021 0.3737 0.3737
Echinococcus multilocularis G-protein coupled receptor, putative 0.021 0.3737 0.3737
Schistosoma mansoni glutaminase 0.018 0.3174 0.3174
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0026 0.0284 0.0274
Echinococcus granulosus dna polymerase eta 0.0016 0.0083 0.0083
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Echinococcus multilocularis serotonin receptor 0.021 0.3737 0.3737
Treponema pallidum hypothetical protein 0.0016 0.0088 0.0228
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.0083 0.0083
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.003 0.0352 0.0352
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.046
Echinococcus granulosus neuropeptides capa receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0042 0.0574 0.0565
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.017 0.297 0.297
Brugia malayi Intermediate filament tail domain containing protein 0.0048 0.0699 0.0699
Schistosoma mansoni biogenic amine receptor 0.021 0.3737 0.3737
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0042 0.0574 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0088 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.3737 0.3737
Schistosoma mansoni neuropeptide F-like receptor 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.0026 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0016 0.0083 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.1637 0.1637
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0079 0.1267 0.1267
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0928 0.0928
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0053 0.0784 0.154
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.001 0.001
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0544 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.3737 0.3737
Brugia malayi Importin beta-1 subunit 0.0017 0.0116 0.0116
Echinococcus granulosus SAM and MBT domain containing protein 0.0026 0.0284 0.0283
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0017 0.0114 0.0104
Echinococcus granulosus mitogen activated protein kinase 3 0.0025 0.0251 0.0251
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.001 0.001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0387 0.2886
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0023 0.0229 0.0229
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.017 0.014
Mycobacterium tuberculosis Probable dehydrogenase 0.0053 0.0784 0.154
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.021 0.3737 0.3737
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0054 0.0796 0.0796
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.007 0.1097 0.5709
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0046 0.0659 0.0631
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.0078
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0088 0.0078
Trypanosoma brucei unspecified product 0.0016 0.0083 0.0429
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0054 0.0796 0.0796
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0088 0.0697
Echinococcus granulosus neuropeptide FF receptor 2 0.021 0.3737 0.3737
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0735 0.5698
Echinococcus multilocularis General substrate transporter 0.0054 0.0807 0.0807
Echinococcus granulosus alpha 1A adrenergic receptor 0.021 0.3737 0.3737
Brugia malayi Phospholipase A2 family protein 0.0103 0.1714 0.1714
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0034 0.0435 0.0435
Schistosoma mansoni synaptojanin 0.0016 0.0088 0.0088
Echinococcus granulosus g-protein coupled receptor 0.021 0.3737 0.3737
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0001
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0199 0.0189
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0088 0.0088
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0036 0.047 0.047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0079 0.1267 0.8626
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0114 0.0084
Brugia malayi TAR-binding protein 0.0165 0.2879 0.2879
Brugia malayi beta-lactamase family protein 0.0042 0.0579 0.0579
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0251 0.0222
Schistosoma mansoni ap endonuclease 0.0079 0.1267 0.1267
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0089 0.1468 0.1468
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.085 0.0841
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Echinococcus multilocularis lysosomal alpha glucosidase 0.0209 0.3705 0.3705
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0088 0.0078
Plasmodium vivax SET domain protein, putative 0.007 0.1097 0.8657
Schistosoma mansoni amine GPCR 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus neuropeptide s receptor 0.0444 0.8116 0.8116
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0088 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0083 0.0429
Toxoplasma gondii ABC1 family protein 0.0042 0.0579 0.3013
Leishmania major importin beta-1 subunit, putative 0.0014 0.0054 0.0197
Schistosoma mansoni hypothetical protein 0.0176 0.3087 0.3087
Echinococcus granulosus transcription factor Dp 1 0.0018 0.0136 0.0136
Echinococcus granulosus chromobox protein 1 0.0045 0.0641 0.0641
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0248 0.176
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.001 0.001
Schistosoma mansoni sex comb on midleg homolog 0.0026 0.0284 0.0283
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0248 0.0218
Echinococcus multilocularis Protein lozenge 0.0057 0.0867 0.0867
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0054 0.0796 0.0796
Schistosoma mansoni intermediate filament proteins 0.0048 0.0699 0.0698
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0032 0.0387 0.0377
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0088 0.0473
Loa Loa (eye worm) beta-lactamase 0.0042 0.0579 0.0569
Onchocerca volvulus 0.021 0.3737 0.3732
Onchocerca volvulus 0.021 0.3737 0.3732
Echinococcus granulosus biogenic amine 5HT receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0042 0.0579 0.0569
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0579 0.0551
Brugia malayi hypothetical protein 0.005 0.0735 0.0735
Schistosoma mansoni hypothetical protein 0.0054 0.0796 0.0796
Echinococcus multilocularis neuropeptides capa receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0088 0.0078
Echinococcus granulosus muscleblind protein 0.0344 0.6232 0.6232
Brugia malayi MAP kinase sur-1 0.0025 0.0251 0.0251
Loa Loa (eye worm) acetylcholinesterase 1 0.0025 0.0266 0.0256
Schistosoma mansoni hypothetical protein 0.0099 0.1639 0.1639
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0251 0.0222
Loa Loa (eye worm) MBCTL1 0.003 0.0352 0.0342
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.1267 0.1241
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0054 0.0024
Brugia malayi ecdysteroid receptor 0.0012 0.001 0.001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Schistosoma mansoni tar DNA-binding protein 0.0165 0.2879 0.2879
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0042 0.0574 0.4245
Giardia lamblia Pyruvate kinase 0.0022 0.0199 0.1355
Plasmodium vivax glutathione reductase, putative 0.0023 0.0226 0.1782
Schistosoma mansoni transcription factor LCR-F1 0.0062 0.0946 0.0946
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.3737 0.3737
Echinococcus granulosus histone lysine methyltransferase setb 0.0098 0.1637 0.1637
Onchocerca volvulus 0.021 0.3737 0.3732
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Onchocerca volvulus Phospholipase A2 homolog 0.0103 0.1714 0.1706
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0079 0.1267 0.9792
Schistosoma mansoni zinc finger protein 0.0036 0.0471 0.0471
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.047 0.1351
Loa Loa (eye worm) thioredoxin reductase 0.0023 0.0226 0.0216
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0079 0.1267 1
Schistosoma mansoni hypothetical protein 0.0185 0.3265 0.3265
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0034 0.0435 0.0435
Echinococcus multilocularis sex peptide receptor 0.021 0.3737 0.3737
Schistosoma mansoni nuclear hormone receptor 0.0012 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Brugia malayi hypothetical protein 0.0458 0.8373 0.8373
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.021 0.3737 0.3737
Echinococcus multilocularis survival motor neuron protein 1 0.0483 0.8852 0.8852
Brugia malayi cytoplasmic intermediate filament protein 0.0026 0.0277 0.0277
Brugia malayi Glycosyl hydrolases family 31 protein 0.0046 0.0659 0.0659
Trichomonas vaginalis helicase, putative 0.0013 0.0031 0.0001
Schistosoma mansoni neuropeptide receptor 0.021 0.3737 0.3737
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.2086 0.2086
Loa Loa (eye worm) hypothetical protein 0.0103 0.1714 0.1705
Brugia malayi Glycosyl hydrolases family 31 protein 0.0209 0.3705 0.3705
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0014 0.006 0.0105
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.047 0.047
Trypanosoma brucei glucosidase, putative 0.0046 0.0659 0.5086
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0116 0.0603
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0053 0.0784 0.154
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0214 0.0214
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0088 0.0473
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis chromobox protein 1 0.0045 0.0641 0.0641
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0114 0.0084
Schistosoma mansoni chromobox protein 0.0045 0.0641 0.0641
Entamoeba histolytica hypothetical protein 0.0014 0.0054 0.0197
Onchocerca volvulus 0.0023 0.0221 0.0211
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0114 0.0084
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0089 0.1468 0.7644
Onchocerca volvulus 0.021 0.3737 0.3732
Schistosoma mansoni thyroid hormone receptor 0.0012 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0026 0.0275 0.1981
Trichomonas vaginalis glucosylceramidase, putative 0.0112 0.1888 0.1865
Brugia malayi Bromodomain containing protein 0.013 0.2226 0.2226
Schistosoma mansoni histamine h1 receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0088 0.0078
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0024 0.0248 0.1288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.0344 0.6232 0.6228
Brugia malayi RNA binding protein 0.0165 0.2879 0.2879
Brugia malayi ORL1-like opioid receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.006 0.0918 0.0918
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.006 0.0918 0.0918
Schistosoma mansoni myelin transcription factor 1 myt1 0.003 0.0352 0.0352
Onchocerca volvulus 0.0099 0.1639 0.1631
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0089 0.1468 0.1468
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Plasmodium falciparum thioredoxin reductase 0.0023 0.0226 0.1782
Loa Loa (eye worm) hypothetical protein 0.0023 0.0221 0.0211
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0088 0.0473
Mycobacterium tuberculosis Probable reductase 0.0053 0.0784 0.154
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0088 0.0088
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0046 0.0659 0.5086
Brugia malayi Serotonin receptor 0.021 0.3737 0.3737
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Brugia malayi hypothetical protein 0.021 0.3737 0.3737
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0088 0.0086
Mycobacterium leprae Probable pyruvate kinase PykA 0.0022 0.0199 0.1222
Leishmania major alpha glucosidase II subunit, putative 0.0046 0.0659 0.5086
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0023 0.0226 0.0373
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.001 0.001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0088 0.0088
Echinococcus granulosus importin subunit beta 1 0.0017 0.0116 0.0116
Onchocerca volvulus 0.021 0.3737 0.3732
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.021 0.3737 0.3737
Echinococcus multilocularis microtubule associated protein 2 0.0456 0.8333 0.8333
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0089 0.1468 0.1468
Echinococcus granulosus synaptojanin 1 0.0016 0.0088 0.0088
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.021 0.3737 0.3737
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0098 0.1637 0.1637
Echinococcus multilocularis polycomb protein SCMH1 0.0026 0.0284 0.0283
Echinococcus multilocularis inositol monophosphatase 1 0.0024 0.0248 0.0247
Echinococcus multilocularis transcription factor Dp 1 0.0018 0.0136 0.0136
Trypanosoma cruzi pyruvate kinase 2, putative 0.0022 0.0199 0.1368
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Schistosoma mansoni zinc finger protein 0.0026 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.0078
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0088 0.0473
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0083 0.0429
Schistosoma mansoni hypothetical protein 0.0495 0.9067 0.9067
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0088 0.0473
Loa Loa (eye worm) G-protein coupled receptor 0.021 0.3737 0.373
Toxoplasma gondii thioredoxin reductase 0.0023 0.0226 0.1175
Brugia malayi mbt repeat family protein 0.0026 0.0284 0.0284
Mycobacterium ulcerans hypothetical protein 0.0042 0.0579 0.1699
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.2987 0.2968
Echinococcus granulosus thyrotropin releasing hormone receptor 0.021 0.3737 0.3737
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0062 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.021 0.3737 0.373
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0735 0.5698
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.001 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.001 0.001
Leishmania major trypanothione reductase 0.0023 0.0226 0.1584
Loa Loa (eye worm) glutaminase 0.018 0.3174 0.3168
Echinococcus granulosus neuropeptide Y receptor 0.021 0.3737 0.3737
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0088 0.0697
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0032 0.0387 0.0387
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.1026 0.1026
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0047 0.0047
Schistosoma mansoni neuropeptide f receptor 76f 0.021 0.3737 0.3737
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0088 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.017 0.014
Schistosoma mansoni hypothetical protein 0.0495 0.9067 0.9067
Onchocerca volvulus 0.0014 0.0047 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0641 0.0613
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.017 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.3737 0.3737
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0659 0.0631
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0387 0.2886
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0209 0.3705 0.3698
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.3737 0.3737
Onchocerca volvulus 0.021 0.3737 0.3732
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0047 0.0141
Trichomonas vaginalis inositol monophosphatase, putative 0.0024 0.0248 0.0218
Schistosoma mansoni biogenic amine (5HT) receptor 0.021 0.3737 0.3737
Schistosoma mansoni hypothetical protein 0.0268 0.482 0.482
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0089 0.1468 0.1468

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 25 uM Inhibition of human recombinant IGF1 receptor ChEMBL. 17317169
IC50 (binding) > 25 uM Inhibition of human recombinant IGF1 receptor ChEMBL. 17317169

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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