Detailed information for compound 546491

Basic information

Technical information
  • TDR Targets ID: 546491
  • Name: 4-benzyloxybenzoic acid
  • MW: 228.243 | Formula: C14H12O3
  • H donors: 1 H acceptors: 2 LogP: 2.91 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1ccc(cc1)OCc1ccccc1
  • InChi: 1S/C14H12O3/c15-14(16)12-6-8-13(9-7-12)17-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16)
  • InChiKey: AQSCHALQLXXKKC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-phenylmethoxybenzoic acid
  • 4-benzoxybenzoic acid
  • 4-(phenylmethoxy)benzoic acid
  • 4-(benzyloxy)benzoic acid
  • 1486-51-7
  • Benzoic acid, 4-(phenylmethoxy)-
  • Brl 14280
  • EINECS 216-066-0
  • NSC 16633
  • p-(Benzyloxy)benzoic acid
  • ST5308765
  • NSC16633
  • SR-01000633233-1
  • InChI=1/C14H12O3/c15-14(16)12-6-8-13(9-7-12)17-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16
  • Oprea1_723890
  • 512354_ALDRICH
  • ARONIS010263
  • AIDS-027812
  • AIDS027812

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0069 0.0858
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0072 0.0178 0.1886
Echinococcus granulosus thioredoxin glutathione reductase 0.0208 0.063 0.063
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0088 0.0932
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0261 0.0805 0.0805
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0031 0.0176
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0007 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0937 1
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0019 0.0002 0.0002
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0261 0.0805 1
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0805 0.2016
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0173 0.1834
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0019 0.0002 0.0021
Schistosoma mansoni retinoic acid receptor RXR 0.0039 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0119 0.0334 0.0334
Leishmania major hypothetical protein, conserved 0.0019 0.0002 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0173 0.2147
Onchocerca volvulus Huntingtin homolog 0.0119 0.0334 0.0837
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0051 0.0051
Schistosoma mansoni sulfide quinone reductase 0.0019 0.0002 0.0002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.079 0.256 0.256
Loa Loa (eye worm) hhat protein 0.0261 0.0805 0.0805
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0021 0.0009 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0088 0.1098
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0031 0.0318
Echinococcus multilocularis RUN 0.002 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0072 0.0178 0.2207
Brugia malayi nuclear receptor NHR-88 0.0039 0.0069 0.0069
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0004 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1075 0.3503 0.3503
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.2149 0.2149
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0231 0.0705 0.0705
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0148 0.0429 0.0429
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0261 0.0805 0.0805
Trypanosoma cruzi GUP1, putative 0.0261 0.0805 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0485 0.1547 0.1547
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0261 0.0805 0.0805
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0031 0.0318
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0019 0.0002 0.0003
Brugia malayi diacylglycerol acyltransferase 0.0261 0.0805 0.0805
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0072 0.0178 0.2207
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0261 0.0805 0.0805
Mycobacterium leprae Probable lipase LipE 0.0071 0.0173 0.1013
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0072 0.0178 0.2207
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0081 0.0203
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0261 0.0805 0.0805
Schistosoma mansoni sterol O-acyltransferase 1 0.0261 0.0805 0.0805
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0016 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0261 0.0805 0.0805
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0261 0.0805 0.0805
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0937 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Onchocerca volvulus 0.0039 0.0069 0.0173
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.027 0.335
Loa Loa (eye worm) histone methyltransferase 0.0041 0.0074 0.0074
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0173 0.0433
Brugia malayi hypothetical protein 0.0146 0.0423 0.0423
Echinococcus granulosus o acyltransferase membrane bound domain 0.0261 0.0805 0.0805
Plasmodium vivax thioredoxin reductase, putative 0.0208 0.063 0.7819
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0019 0.0002 0.0018
Trichomonas vaginalis glutamate synthase, putative 0.0019 0.0002 0.0004
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0019 0.0002 0.0031
Entamoeba histolytica disulphide oxidoreductase, putative 0.0019 0.0002 0.0021
Schistosoma mansoni glutamate synthase 0.0019 0.0002 0.0002
Trypanosoma brucei NADH dehydrogenase 0.0019 0.0002 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0231 0.0705 0.1764
Leishmania major glycerol uptake protein, putative 0.0261 0.0805 0.8591
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0031 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0031 0.0176
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0112 0.1197
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0024 0.006
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0019 0.0002 0.0024
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0021 0.0009 0.0087
Mycobacterium ulcerans hypothetical protein 0.0071 0.0173 0.1834
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0069 0.0069
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0261 0.0805 1
Plasmodium falciparum thioredoxin reductase 0.0208 0.063 0.7819
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0476 0.1515 0.8959
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0019 0.0002 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0031 0.0176
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0019 0.0002 0.0004
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0019 0.0002 0.0006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0019 0.0002 0.0003
Echinococcus granulosus RUN 0.002 0.0004 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.053 0.053
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0529 0.1691 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0156 0.0456 0.0456
Trichomonas vaginalis set domain proteins, putative 0.1223 0.3994 1
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0021 0.0009 0.0045
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0072 0.0178 0.2207
Echinococcus multilocularis ubiquitin specific protease 41 0.0231 0.0705 0.0705
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0231 0.0705 0.0705
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0031 0.0384
Toxoplasma gondii thioredoxin reductase 0.0208 0.063 0.6717
Trichomonas vaginalis porcupine, putative 0.0261 0.0805 0.2016
Plasmodium falciparum glutathione reductase 0.0208 0.063 0.7819
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Loa Loa (eye worm) acetyltransferase 0.0147 0.0424 0.0424
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0069 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Loa Loa (eye worm) doublecortin family protein 0.002 0.0004 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0069 0.0069
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0112 0.1393
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Echinococcus multilocularis tumor protein p63 0.0334 0.1045 0.1045
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0173 0.0173
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0031 0.0318
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0261 0.0805 0.0805
Echinococcus multilocularis thioredoxin glutathione reductase 0.0208 0.063 0.063
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0069 0.0069
Brugia malayi hypothetical protein 0.0034 0.005 0.005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0231 0.0705 0.1764
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0004 0.0052
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0019 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0805 0.2016
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0009 0.0087
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0231 0.0705 0.875
Leishmania major hypothetical protein, conserved 0.0019 0.0002 0.0018
Trypanosoma cruzi GUP1, putative 0.0261 0.0805 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0069 0.0069
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0231 0.0705 0.875
Entamoeba histolytica hypothetical protein 0.0261 0.0805 1
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0112 0.1393
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0001 0.0001
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.027 0.2878
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0178 0.053 0.053
Mycobacterium tuberculosis Probable aminotransferase 0.0151 0.0439 0.2589
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0069 0.0069
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0088 0.1098
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0031 0.0176
Entamoeba histolytica hypothetical protein 0.0146 0.0423 0.5259
Entamoeba histolytica hypothetical protein 0.0146 0.0423 0.5259
Leishmania major hypothetical protein, conserved 0.0019 0.0002 0.0018
Brugia malayi Cytochrome P450 family protein 0.0028 0.0031 0.0031
Schistosoma mansoni glutamate synthase 0.0019 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Schistosoma mansoni hypothetical protein 0.0146 0.0423 0.0423
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0031 0.0318
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0173 0.0173
Loa Loa (eye worm) beta-lactamase 0.0071 0.0173 0.0173
Echinococcus granulosus microtubule associated protein 2 0.0667 0.2149 0.2149
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0031 0.0318
Brugia malayi glutamate synthase 0.0019 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0031 0.0318
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0019 0.0002 0.0003
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0009 0.0087
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0074 0.0074
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0031 0.0176
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0019 0.0002 0.0021
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0019 0.0002 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0112 0.1393
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.027 0.027
Mycobacterium tuberculosis Conserved protein 0.0071 0.0173 0.1016
Loa Loa (eye worm) hypothetical protein 0.0156 0.0456 0.0456
Echinococcus multilocularis thyroid hormone receptor alpha 0.0039 0.0069 0.0069
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0173 0.1016
Trichomonas vaginalis CMGC family protein kinase 0.01 0.027 0.0675
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0069 0.0069
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0231 0.0705 0.875
Schistosoma mansoni polycystin 1-related 0.002 0.0004 0.0004
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0021 0.0009 0.0048
Trypanosoma brucei glycerol uptake protein, putative 0.0261 0.0805 1
Schistosoma mansoni aldehyde dehydrogenase 0.0301 0.0937 0.0937
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0021 0.0009 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.01 0.027 0.0675
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0231 0.0705 0.7517
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0069 0.0069
Onchocerca volvulus 0.0071 0.0173 0.0433
Trypanosoma brucei trypanothione reductase 0.0208 0.063 0.7819
Brugia malayi beta-lactamase family protein 0.0071 0.0173 0.0173
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0019 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0031 0.0318
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0001 0.0014
Plasmodium vivax ornithine aminotransferase, putative 0.0021 0.0009 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0069 0.0069
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0072 0.0178 0.2207
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0019 0.0002 0.0021
Plasmodium falciparum ferrodoxin reductase-like protein 0.0019 0.0002 0.0021
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0031 0.0384
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0019 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0031
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0019 0.0002 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0069 0.0069
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.027 0.335
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0031 0.0384
Trichomonas vaginalis glutathione reductase, putative 0.0072 0.0178 0.0445
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.0316 0.0316
Schistosoma mansoni aldehyde dehydrogenase 0.0301 0.0937 0.0937
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0053 0.0114 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0031 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0069 0.0069
Echinococcus granulosus cpg binding protein 0.0121 0.0338 0.0338
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0173 0.0433
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0334 0.0334
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0072 0.0178 0.1886
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0173 0.0173
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.1896
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0019 0.0002 0.0006
Entamoeba histolytica hypothetical protein 0.0146 0.0423 0.5259
Trypanosoma cruzi NADH dehydrogenase, putative 0.0019 0.0002 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0173 0.1016
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0019 0.0002 0.0002
Echinococcus granulosus ornithine aminotransferase 0.0021 0.0009 0.0009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0072 0.0178 0.2207
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0173 0.1016
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0019 0.0002 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0069 0.0069
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0261 0.0805 0.0805
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0009 0.0009
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0231 0.0705 0.0705
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0019 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0261 0.0805 0.8591
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0112 0.1393
Schistosoma mansoni cpg binding protein 0.0121 0.0338 0.0338
Onchocerca volvulus 0.0071 0.0173 0.0433
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0156 0.0456 0.0456
Brugia malayi Pre-SET motif family protein 0.0156 0.0456 0.0456
Plasmodium falciparum glutathione reductase 0.0072 0.0178 0.2207
Brugia malayi Pre-SET motif family protein 0.1075 0.3503 0.3503
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.053 0.053
Echinococcus granulosus ubiquitin specific protease 41 0.0231 0.0705 0.0705
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0051 0.0051
Mycobacterium tuberculosis Probable reductase 0.0476 0.1515 0.8959
Leishmania major glycerol uptake protein, putative 0.0261 0.0805 0.8591
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0261 0.0805 0.0805
Treponema pallidum thioredoxin reductase (trxB) 0.0019 0.0002 0.0007
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0019 0.0002 0.0002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0069 0.0069
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0072 0.0178 0.1896
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0021 0.0009 0.0045
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0031 0.0176
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0019 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.0705 0.1764
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0019 0.0002 0.0021
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0004 0.0004
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0261 0.0805 0.0805
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0069 0.0069
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0031 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0069 0.0069
Brugia malayi Doublecortin family protein 0.002 0.0004 0.0004
Echinococcus granulosus Aminotransferase class III 0.0021 0.0009 0.0009
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.0072 0.0072
Echinococcus multilocularis dnaJ subfamily B 0.1226 0.4003 0.4003
Loa Loa (eye worm) hypothetical protein 0.0231 0.0705 0.0705
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.027 0.027
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0261 0.0805 0.0805
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0173 0.1834
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0069 0.0069
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0231 0.0705 0.0705
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0007 0.0007
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0261 0.0805 0.0805
Schistosoma mansoni cpg binding protein 0.0114 0.0316 0.0316
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0019 0.0002 0.0002
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.3034 1 1
Brugia malayi CXXC zinc finger family protein 0.0114 0.0316 0.0316
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0069 0.0069
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0019 0.0002 0.0021
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0261 0.0805 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0031 0.0176
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0019 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0173 0.2147
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0069 0.0069
Schistosoma mansoni eyes absent homolog 0.0085 0.022 0.022
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0069 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0173 0.2147
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0081 0.1006
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.027 0.335
Trichomonas vaginalis transmembrane protein nessy, putative 0.0261 0.0805 0.2016
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0069 0.0069
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0019 0.0002 0.0002
Treponema pallidum alginate O-acetylation protein (algI) 0.0261 0.0805 1
Trichomonas vaginalis esterase, putative 0.0071 0.0173 0.0433
Trypanosoma cruzi trypanothione reductase, putative 0.0072 0.0178 0.2207
Echinococcus granulosus dnaJ subfamily B 0.1226 0.4003 0.4003
Leishmania major cytochrome p450-like protein 0.0028 0.0031 0.033
Mycobacterium ulcerans acetylornithine aminotransferase 0.0021 0.0009 0.0087
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0173 0.1016
Schistosoma mansoni rab6-interacting 0.002 0.0004 0.0004
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0261 0.0805 0.0805
Brugia malayi MBOAT family protein 0.0261 0.0805 0.0805
Toxoplasma gondii NADPH-glutathione reductase 0.0072 0.0178 0.1896
Echinococcus granulosus sterol O acyltransferase 1 0.0261 0.0805 0.0805
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0261 0.0805 0.0805
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0424 0.0424
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0031 0.0176
Leishmania major trypanothione reductase 0.0208 0.063 0.6717
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0019 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0088 0.0088
Echinococcus granulosus zinc finger protein 0.2772 0.9133 0.9133
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.053 0.053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0069 0.0069
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0021 0.0009 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0937 1
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0019 0.0002 0.0002
Loa Loa (eye worm) MBOAT family protein 0.0261 0.0805 0.0805
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0151 0.0439 0.1099
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0088 0.0088
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0261 0.0805 1
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0019 0.0002 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0003
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0019 0.0002 0.0021
Plasmodium vivax glutathione reductase, putative 0.0208 0.063 0.7819
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0173 0.0433
Plasmodium vivax ferrodoxin reductase, putative 0.0019 0.0002 0.0021
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0069 0.0981
Brugia malayi beta-lactamase family protein 0.0071 0.0173 0.0173
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0156 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Mycobacterium ulcerans L-lysine aminotransferase 0.0021 0.0009 0.0087
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0476 0.1515 0.8959
Schistosoma mansoni lipoxygenase 0.0083 0.0215 0.0215
Mycobacterium ulcerans lipase LipD 0.0071 0.0173 0.1834
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Trypanosoma cruzi glycerol uptake protein, putative 0.0261 0.0805 1
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0001 0.0001
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0424 0.0424
Leishmania major hypothetical protein, conserved 0.0052 0.0112 0.1197
Brugia malayi follicle stimulating hormone receptor 0.0739 0.2389 0.2389
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0178 0.053 0.053
Schistosoma mansoni cpg binding protein 0.0121 0.0338 0.0338
Loa Loa (eye worm) MBOAT family protein 0.0261 0.0805 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Leishmania major hypothetical protein, conserved 0.0071 0.0173 0.1844
Plasmodium vivax SET domain protein, putative 0.0156 0.0456 0.5669
Toxoplasma gondii hypothetical protein 0.0261 0.0805 0.8591
Brugia malayi MBOAT family protein 0.0261 0.0805 0.0805
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0019 0.0002 0.0021
Echinococcus multilocularis glutamate synthase 0.0019 0.0002 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0069 0.0069
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0476 0.1515 0.8958
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.053 0.053
Mycobacterium ulcerans beta-lactamase 0.0071 0.0173 0.1834
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0019 0.0002 0.0002
Treponema pallidum NADH oxidase 0.0072 0.0178 0.2196
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0088 0.1098
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0007 0.0007
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0004 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.01 0.01
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0019 0.0002 0.0006
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0021 0.0009 0.046
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0031 0.0318
Trypanosoma cruzi NADH dehydrogenase, putative 0.0019 0.0002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0081 0.0865
Schistosoma mansoni hypothetical protein 0.0261 0.0805 0.0805
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0024 0.006
Schistosoma mansoni peptidase 0.002 0.0003 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0112 0.1393
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0529 0.1691 1
Leishmania major cytochrome p450-like protein 0.0045 0.0088 0.0943
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0173 0.0433
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0019 0.0002 0.0031
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0069 0.0069
Plasmodium falciparum ornithine aminotransferase 0.0021 0.0009 0.0115
Loa Loa (eye worm) programmed cell death 8 0.0019 0.0002 0.0002
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0019 0.0002 0.0021
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.2149 0.2149
Schistosoma mansoni ap endonuclease 0.0019 0.0001 0.0001
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0004 0.0004
Brugia malayi glutathione reductase 0.0208 0.063 0.063
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0031 0.0176
Onchocerca volvulus 0.0049 0.01 0.0251
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.0685 0.7314
Toxoplasma gondii ABC1 family protein 0.0071 0.0173 0.1844
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0069 0.0858
Echinococcus multilocularis Aminotransferase class III 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0031 0.0176
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0019 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Echinococcus multilocularis muscleblind protein 0.0938 0.3048 0.3048
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0031 0.0318
Onchocerca volvulus 0.0019 0.0002 0.0004
Echinococcus multilocularis zinc finger protein 0.2772 0.9133 0.9133
Brugia malayi Hhat protein 0.0261 0.0805 0.0805
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0001 0.0017
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0019 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0173 0.2147
Leishmania major glycerol uptake protein, putative 0.0261 0.0805 0.8591
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0031 0.0176
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0072 0.0178 0.1045
Onchocerca volvulus 0.002 0.0004 0.0011
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0261 0.0805 0.0805
Plasmodium falciparum thioredoxin reductase 0.0072 0.0178 0.2207
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0069 0.0069
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0019 0.0002 0.0004
Schistosoma mansoni glutamate synthase 0.0019 0.0002 0.0002
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0261 0.0805 0.0805
Trichomonas vaginalis apoptosis inducing factor, putative 0.0019 0.0002 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0002 0.0021
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0072 0.0178 0.2207
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0069 0.0069
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0019 0.0002 0.0021
Loa Loa (eye worm) MBOAT family protein 0.3034 1 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0476 0.1515 0.8959
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0007 0.0007
Trypanosoma brucei glycerol uptake protein, putative 0.0261 0.0805 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0231 0.0705 0.0705
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0001 0.0014
Echinococcus multilocularis 0.0028 0.0031 0.0031
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.027 0.335
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0031 0.0318
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0019 0.0002 0.0003
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0151 0.0439 0.4676
Schistosoma mansoni sulfide quinone reductase 0.0019 0.0002 0.0002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.027 0.2878
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Toxoplasma gondii aldehyde dehydrogenase 0.0301 0.0937 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0151 0.0439 0.2587
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0019 0.0002 0.0021
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0031 0.0318
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.1896
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0069 0.0069
Brugia malayi hypothetical protein 0.0119 0.0334 0.0334
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.1438 0.8499
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0156 0.0456 0.487
Trypanosoma brucei protein kinase, putative 0.01 0.027 0.335
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Schistosoma mansoni hypothetical protein 0.0024 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0069 0.0069
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0072 0.0178 0.1896
Trichomonas vaginalis CMGC family protein kinase 0.01 0.027 0.0675
Onchocerca volvulus 0.1223 0.3994 1
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0069 0.0069
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0072 0.0178 0.0178
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.3034 1 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0072 0.0178 0.0178
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0072 0.0178 0.0178
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0069 0.0069
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0031 0.0318
Giardia lamblia Thioredoxin reductase 0.0019 0.0002 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0248 0.0759 0.0759
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0151 0.0439 0.2589
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0031 0.0318
Brugia malayi Cytochrome P450 family protein 0.0103 0.0281 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0024 0.006
Mycobacterium ulcerans ferredoxin reductase 0.0019 0.0002 0.0006
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0031 0.0318
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0231 0.0705 1
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0069 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0031 0.0176
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0069 0.0069
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0019 0.0002 0.0021
Schistosoma mansoni hypothetical protein 0.1226 0.4003 0.4003
Brugia malayi Thioredoxin reductase 0.0208 0.063 0.063
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0261 0.0805 0.0805
Brugia malayi Muscleblind-like protein 0.0938 0.3048 0.3048
Echinococcus granulosus tumor protein p63 0.0334 0.1045 0.1045
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0423 0.0423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.053 0.053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.053 0.053
Echinococcus multilocularis sterol O acyltransferase 1 0.0261 0.0805 0.0805
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0031 0.0176
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0424 0.0424
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0088 0.0088
Leishmania major glycerol uptake protein, putative 0.0261 0.0805 0.8591
Schistosoma mansoni disulfide oxidoreductase 0.0019 0.0002 0.0002
Trichomonas vaginalis helicase, putative 0.0026 0.0024 0.006
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0021 0.0009 0.0087
Mycobacterium ulcerans dehydrogenase 0.0019 0.0002 0.0006
Brugia malayi ecdysteroid receptor 0.0039 0.0069 0.0069
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0031 0.0318
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0173 0.1016
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0019 0.0002 0.0031
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0476 0.1515 0.8959
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0031 0.0176
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0156 0.0456 0.0456
Brugia malayi nuclear hormone receptor 0.0039 0.0069 0.0069
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0072 0.0178 0.2207
Schistosoma mansoni cytochrome P450 0.0028 0.0031 0.0031
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0072 0.0178 0.2207
Mycobacterium ulcerans glutamate synthase subunit beta 0.0019 0.0002 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0031 0.0176
Echinococcus multilocularis cpg binding protein 0.0121 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0085 0.022 0.022
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0031 0.0384
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0019 0.0002 0.0018
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0019 0.0002 0.0004
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0019 0.0002 0.0018
Giardia lamblia Glutamate synthase 0.0019 0.0002 0.0024
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0021 0.0009 0.0009
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0004 0.0004
Entamoeba histolytica thioredoxin reductase, putative 0.0019 0.0002 0.0021
Trichomonas vaginalis glutamate synthase, putative 0.0019 0.0002 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0112 0.1393
Brugia malayi cytochrome P450 0.0028 0.0031 0.0031
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0031 0.0318
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0019 0.0002 0.0018
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0021 0.0009 0.0048
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0039 0.0069 0.0069
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0261 0.0805 0.0805
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0069 0.0173
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0074 0.0074
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0031 0.0031
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0016 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0001 0.0014
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0261 0.0805 0.8591
Loa Loa (eye worm) hypothetical protein 0.0119 0.0334 0.0334
Leishmania major NADH dehydrogenase, putative 0.0019 0.0002 0.0018
Entamoeba histolytica vacuolar protein sorting 26 0.0261 0.0805 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0173 0.0173
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0019 0.0002 0.0021
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0004 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0301 0.0937 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0069 0.0069
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0069 0.0069
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0069 0.0173
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0069 0.0173
Onchocerca volvulus 0.002 0.0004 0.0011
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0051 0.0051
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0069 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor A26 0.0485 0.1547 0.1547
Onchocerca volvulus 0.0156 0.0456 0.1143
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0208 0.063 0.3718
Echinococcus granulosus neuropeptide s receptor 0.0485 0.1547 0.1547
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.027 0.027
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0001 0.0014
Trichomonas vaginalis mercuric reductase, putative 0.0072 0.0178 0.0445
Toxoplasma gondii exonuclease III APE 0.0019 0.0001 0.0012
Schistosoma mansoni loxhd1 0.002 0.0004 0.0004
Schistosoma mansoni ap endonuclease 0.0019 0.0001 0.0001
Schistosoma mansoni zinc finger protein 0.3034 1 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0031 0.0176
Onchocerca volvulus 0.0261 0.0805 0.2016
Trypanosoma cruzi glycerol uptake protein, putative 0.0261 0.0805 1
Brugia malayi MBOAT family protein 0.0261 0.0805 0.0805
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0001 0.0014
Onchocerca volvulus 0.0114 0.0316 0.0792
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.027 0.027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0081 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0031 0.0176
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0069 0.0069
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0069 0.0069
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0231 0.0705 0.0705
Echinococcus granulosus muscleblind protein 0.0938 0.3048 0.3048
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0019 0.0002 0.0021
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0423 0.0423
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0019 0.0002 0.0021
Schistosoma mansoni coup transcription factor 0.0039 0.0069 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0069 0.0069
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0053 0.0114 0.0114
Mycobacterium leprae putative cytochrome p450 0.0028 0.0031 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0938 0.3048 0.3048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0456 0.0456
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0031 0.033
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0072 0.0178 0.2207
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0031 0.0176
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0051 0.0051
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0019 0.0002 0.0021
Brugia malayi nuclear receptor RXR 0.0021 0.0007 0.0007
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0261 0.0805 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.027 0.335
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0019 0.0002 0.0004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0231 0.0705 0.875
Brugia malayi Cytochrome P450 family protein 0.0045 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0001 0.0012
Giardia lamblia Kinase, CMGC MAPK 0.01 0.027 0.3829
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.027 0.2878
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.002 0.0004 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0069 0.0069
Echinococcus multilocularis neuropeptide receptor A26 0.0485 0.1547 0.1547
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0476 0.1515 0.8959
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0031 0.033
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0231 0.0705 0.0705
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0031 0.0318
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0173 0.1016
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0019 0.0002 0.0006
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.041 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.053 0.053
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0072 0.0178 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0301 0.0937 0.5538
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0072 0.0178 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0529 0.1691 1
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0261 0.0805 0.8591
Brugia malayi hypothetical protein 0.0085 0.022 0.022
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0019 0.0002 0.0021
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0009 0.0009
Schistosoma mansoni rab6-interacting 0.002 0.0004 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0423 0.0423
Loa Loa (eye worm) thioredoxin reductase 0.0208 0.063 0.063
Brugia malayi hypothetical protein 0.0052 0.0112 0.0112
Entamoeba histolytica hypothetical protein 0.0146 0.0423 0.5259
Mycobacterium tuberculosis Conserved protein 0.0071 0.0173 0.1016
Schistosoma mansoni lipoxygenase 0.0119 0.0334 0.0334
Echinococcus multilocularis muscleblind protein 1 0.0938 0.3048 0.3048
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0301 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0071 0.0173 0.0173
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0051 0.0051
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0261 0.0805 0.0805
Loa Loa (eye worm) hhat protein 0.0261 0.0805 0.0805
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0301 0.0937 0.0937
Loa Loa (eye worm) glutathione reductase 0.0208 0.063 0.063
Treponema pallidum oxidoreductase 0.0019 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0112 0.0112
Echinococcus granulosus glutamate synthase 0.0019 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0151 0.0439 0.4676
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0021 0.0009 0.0431
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0069 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0173 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0805 0.2016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0173 0.1016
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0072 0.0178 1
Brugia malayi beta-lactamase 0.0071 0.0173 0.0173
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0739 0.2389 0.2389
Loa Loa (eye worm) hypothetical protein 0.0085 0.022 0.022
Leishmania major cytochrome p450-like protein 0.0028 0.0031 0.033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0069 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0173 0.1013
Mycobacterium ulcerans hypothetical protein 0.0019 0.0002 0.0006
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0031 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0938 0.3048 0.3048
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0031 0.0318
Mycobacterium tuberculosis Conserved protein 0.0071 0.0173 0.1016
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0081 0.0081
Echinococcus granulosus o acyltransferase membrane bound domain 0.0261 0.0805 0.0805
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0019 0.0002 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.01 0.027 0.0675
Trypanosoma cruzi trypanothione reductase, putative 0.0208 0.063 0.7819
Brugia malayi Cytochrome P450 family protein 0.0045 0.0088 0.0088
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0031 0.0318
Leishmania major glycerol uptake protein, putative 0.0261 0.0805 0.8591
Entamoeba histolytica hypothetical protein, conserved 0.0261 0.0805 1
Onchocerca volvulus 0.0071 0.0173 0.0433
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0019 0.0002 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0069 0.0069
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0173 0.0173
Trypanosoma cruzi glycerol uptake protein, putative 0.0261 0.0805 1
Toxoplasma gondii selenide, water dikinase 0.0019 0.0002 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0456 0.0456
Brugia malayi MAP kinase sur-1 0.01 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium ulcerans NADH dehydrogenase 0.0019 0.0002 0.0006
Loa Loa (eye worm) cytochrome P450 0.0028 0.0031 0.0031
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0072 0.0178 0.1896
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0261 0.0805 0.0805
Loa Loa (eye worm) hypothetical protein 0.0049 0.01 0.01
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0069 0.0069
Giardia lamblia NADH oxidase lateral transfer candidate 0.0072 0.0178 0.2522
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0261 0.0805 0.0805
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0173 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0024 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0069 0.0069
Echinococcus granulosus mitogen activated protein kinase 0.01 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Onchocerca volvulus Huntingtin homolog 0.0119 0.0334 0.0837
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0069
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0021 0.0009 0.0045
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0261 0.0805 0.0805
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0019 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0456 0.0456
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0072 0.0178 0.0178
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0281 0.0281
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0081 0.0865
Brugia malayi MBOAT family protein 0.0261 0.0805 0.0805
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0072 0.0178 0.1886
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0072 0.0178 0.2207
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0002 0.0004
Echinococcus granulosus o acyltransferase membrane bound domain 0.0261 0.0805 0.0805
Mycobacterium ulcerans monoxygenase 0.0019 0.0002 0.0006
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0001 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0529 0.1691 1
Brugia malayi steroid hormone receptor 0.0039 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.01 0.027 0.027

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 250 uM Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis ChEMBL. 24363888
MIC (functional) > 400 uM Antibacterial activity against Escherichia coli assessed as complete growth inhibition after 24 hrs by standard microdilution assay ChEMBL. 24363888

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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