Detailed information for compound 667839

Basic information

Technical information
  • TDR Targets ID: 667839
  • Name: 2-(2-bromo-4-ethylphenoxy)-N-[4-(4-methylpipe ridin-1-yl)sulfonylphenyl]acetamide
  • MW: 495.43 | Formula: C22H27BrN2O4S
  • H donors: 1 H acceptors: 3 LogP: 4.71 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(c(c1)Br)OCC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(CC1)C
  • InChi: 1S/C22H27BrN2O4S/c1-3-17-4-9-21(20(23)14-17)29-15-22(26)24-18-5-7-19(8-6-18)30(27,28)25-12-10-16(2)11-13-25/h4-9,14,16H,3,10-13,15H2,1-2H3,(H,24,26)
  • InChiKey: YKLDLVBPVVVCTP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-bromo-4-ethyl-phenoxy)-N-[4-[(4-methyl-1-piperidyl)sulfonyl]phenyl]acetamide
  • 2-(2-bromo-4-ethylphenoxy)-N-[4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]acetamide
  • 2-(2-bromo-4-ethyl-phenoxy)-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]ethanamide
  • ZINC00676566
  • STK121516
  • Oprea1_630561
  • AN-329/41609916
  • ARONIS005294

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.026 0.0398 0.0666
Echinococcus granulosus activin receptor type 0.022 0.0254 0.029
Brugia malayi Protein kinase domain containing protein 0.0591 0.1607 0.1607
Schistosoma mansoni protein kinase 0.022 0.0254 0.0464
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1228 0.3928 0.4474
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0303 0.0556 0.4657
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0329 0.0653 0.0653
Trypanosoma cruzi cdc2-related kinase 1 0.0361 0.0766 0.3101
Brugia malayi STE20-like kinase MST 0.0785 0.2315 0.2315
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0305 0.0565 0.2081
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0559 0.1489 0.2489
Loa Loa (eye worm) hypothetical protein 0.0275 0.0453 0.0453
Echinococcus granulosus c-Jun N-terminal kinases 0.0808 0.2398 0.2731
Onchocerca volvulus 0.0427 0.1009 0.2073
Echinococcus granulosus tyrosine protein kinase Src64B 0.0559 0.1489 0.1696
Brugia malayi Cam kinase protein 1 0.0305 0.0565 0.0565
Toxoplasma gondii CMGC kinase, CK2 family 0.0303 0.0557 0.2051
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0372 0.0678
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0247 0.0352 0.0352
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2893 1 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0225 0.0272 0.0454
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0246 0.0348 0.0581
Loa Loa (eye worm) hypothetical protein 0.0593 0.1613 0.1613
Plasmodium vivax serine/threonine kinase-1, putative 0.0468 0.1157 0.9718
Echinococcus granulosus casein kinase I delta 0.0329 0.0653 0.0743
Loa Loa (eye worm) hypothetical protein 0.142 0.4628 0.4628
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1208 0.3856 0.3856
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0796 0.1451
Onchocerca volvulus 0.0256 0.0384 0.0551
Echinococcus multilocularis titin 0.0198 0.0175 0.0292
Echinococcus granulosus protein kinase c iota type 0.0895 0.2717 0.3094
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0633
Schistosoma mansoni protein kinase 0.054 0.1422 0.2592
Loa Loa (eye worm) hypothetical protein 0.0204 0.0197 0.0197
Giardia lamblia Kinase, PLK 0.0827 0.2465 1
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Schistosoma mansoni protein kinase 0.0303 0.0557 0.1015
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0613 0.1686 0.1686
Brugia malayi Temporarily assigned gene name protein 59 0.0397 0.0899 0.0899
Brugia malayi Protein kinase domain containing protein 0.0588 0.1597 0.1597
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0209 0.0215 0.0391
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0734 0.2127 0.3555
Loa Loa (eye worm) AGC/AKT protein kinase 0.0917 0.2795 0.2795
Loa Loa (eye worm) TK/FER protein kinase 0.1059 0.3314 0.3314
Brugia malayi Protein kinase domain containing protein 0.1098 0.3454 0.3454
Brugia malayi Hr1 repeat family protein 0.0911 0.2772 0.2772
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0303 0.0556 0.2246
Onchocerca volvulus 0.0995 0.3081 0.7121
Brugia malayi Protein kinase domain containing protein 0.054 0.142 0.142
Brugia malayi Fibronectin type III domain containing protein 0.0253 0.0372 0.0372
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0047 0.0159
Schistosoma mansoni vesicular amine transporter 0.0209 0.0215 0.0391
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0512 0.1317 0.1501
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Brugia malayi Doublecortin family protein 0.0459 0.1126 0.1126
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.054 0.142 0.142
Trichomonas vaginalis CAMK family protein kinase 0.0346 0.0714 0.2547
Onchocerca volvulus Serine\/threonine kinase homolog 0.05 0.1274 0.272
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1025 0.3188 0.3188
Echinococcus granulosus tyrosine protein kinase Blk 0.0466 0.115 0.131
Schistosoma mansoni growth factor receptor-bound protein 0.0229 0.0287 0.0523
Echinococcus granulosus tyrosine protein kinase HCK 0.0334 0.0669 0.0762
Loa Loa (eye worm) hypothetical protein 0.0427 0.1009 0.1009
Giardia lamblia Kinase, STE STE20 0.026 0.0398 0.1608
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0405 0.0929 0.0929
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0345 0.0709 0.2613
Loa Loa (eye worm) hypothetical protein 0.0316 0.0605 0.0605
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1228 0.3928 0.6566
Echinococcus multilocularis expressed conserved protein 0.0345 0.0709 0.1185
Trichomonas vaginalis CAMK family protein kinase 0.0384 0.0851 0.3039
Schistosoma mansoni vam6/vps39 related 0.0318 0.0612 0.1115
Onchocerca volvulus 0.0329 0.0653 0.1206
Loa Loa (eye worm) hypothetical protein 0.0936 0.2863 0.2863
Entamoeba histolytica PH domain containing protein kinase, putative 0.0502 0.1281 0.3443
Leishmania major protein kinase, putative 0.0443 0.1066 0.4316
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1059 0.3314 0.5539
Plasmodium falciparum protein kinase 5 0.0361 0.0766 0.6429
Loa Loa (eye worm) AGC/PKA protein kinase 0.0303 0.0556 0.0556
Echinococcus multilocularis epidermal growth factor receptor 0.1654 0.5484 0.9167
Giardia lamblia Kinase, NEK 0.0414 0.0961 0.3891
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0305 0.0565 0.2081
Echinococcus granulosus defective proboscis extension response 0.0209 0.0215 0.0244
Echinococcus multilocularis casein kinase I delta 0.0329 0.0653 0.1091
Echinococcus granulosus fibroblast growth factor receptor 4 0.0734 0.2127 0.2422
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0567 0.1518 0.1518
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0468 0.1157 0.1157
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0588 0.1597 0.1597
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0468 0.1157 0.4688
Entamoeba histolytica protein kinase, putative 0.0251 0.0366 0.0978
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0305 0.0565 0.0643
Echinococcus granulosus tyrosine kinase 0.0256 0.0384 0.0437
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.027 0.0437 0.1762
Schistosoma mansoni tyrosine kinase 0.1184 0.377 0.6875
Entamoeba histolytica cell division protein kinase 2, putative 0.0361 0.0766 0.2057
Schistosoma mansoni tyrosine kinase 0.0567 0.1521 0.2773
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0798 0.1455
Echinococcus multilocularis expressed protein 0.0251 0.0366 0.0612
Loa Loa (eye worm) hypothetical protein 0.0256 0.0384 0.0384
Echinococcus granulosus tyrosine protein kinase 0.0861 0.2592 0.2952
Trichomonas vaginalis CMGC family protein kinase 0.0214 0.0234 0.0828
Entamoeba histolytica protein kinase, putative 0.0369 0.0796 0.2137
Echinococcus granulosus serine/threonine protein kinase 0.0502 0.1281 0.1459
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0346 0.0714 0.0714
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.2246 0.4095
Brugia malayi Serine/threonine-protein kinase SULU 0.0679 0.1926 0.1926
Entamoeba histolytica protein kinase, putative 0.0443 0.1066 0.2863
Schistosoma mansoni serine/threonine protein kinase 0.0567 0.1518 0.2768
Brugia malayi MAP kinase sur-1 0.0253 0.0373 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Mycobacterium ulcerans hypothetical protein 0.0248 0.0357 0.5
Echinococcus granulosus cyclin dependent kinase 0.0361 0.0766 0.0873
Schistosoma mansoni serine/threonine protein kinase 0.05 0.1274 0.2324
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0443 0.1066 0.2863
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0559 0.1489 0.2489
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0709 0.2037 0.2037
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0225 0.0272 0.0272
Echinococcus granulosus dual specificity 0.0371 0.0805 0.0917
Echinococcus granulosus serine:threonine protein kinase 0.0346 0.0714 0.0813
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0225 0.0272 0.0272
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0303 0.0556 0.1981
Giardia lamblia Kinase, CMGC DYRK 0.0369 0.0796 0.3221
Echinococcus multilocularis dual specificity 0.0369 0.0796 0.1331
Echinococcus granulosus casein kinase I alpha 0.0329 0.0653 0.0743
Trichomonas vaginalis CK1 family protein kinase 0.0329 0.0653 0.2328
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0929
Brugia malayi probable protein kinase 0.0723 0.2089 0.2089
Echinococcus granulosus titin 0.0198 0.0175 0.0199
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0355 0.0747 0.0747
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0369 0.0796 0.0796
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1098 0.3454 0.3934
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Leishmania major protein kinase, putative 0.0468 0.1157 0.4688
Echinococcus granulosus calcium activated potassium channel 0.0369 0.0798 0.0909
Echinococcus multilocularis neuroglian 0.0268 0.0428 0.0716
Brugia malayi Protein kinase domain containing protein 0.0651 0.1826 0.1826
Echinococcus granulosus neuroglian 0.0268 0.0428 0.0488
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.2246 0.4095
Trichomonas vaginalis CAMK family protein kinase 0.0305 0.0565 0.2014
Brugia malayi serine/threonine-protein kinase plk-2 0.0827 0.2465 0.2465
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0255 0.0383 0.1546
Echinococcus multilocularis death associated protein kinase 1 0.1791 0.5982 1
Echinococcus multilocularis tyrosine kinase 0.0256 0.0384 0.0641
Loa Loa (eye worm) hypothetical protein 0.0258 0.0391 0.0391
Echinococcus multilocularis serine:threonine kinase SAD 1 0.027 0.0437 0.073
Schistosoma mansoni hypothetical protein 0.0273 0.0446 0.0814
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0391 0.0877 0.3236
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0255 0.0383 0.1025
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0485 0.1219 0.4355
Loa Loa (eye worm) hypothetical protein 0.0174 0.0085 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Brugia malayi Protein kinase domain containing protein 0.0256 0.0384 0.0384
Onchocerca volvulus 0.0899 0.2729 0.6265
Onchocerca volvulus 0.0439 0.1054 0.2184
Giardia lamblia Kinase, CMGC SRPK 0.0251 0.0366 0.1475
Brugia malayi SH2 domain containing protein 0.0256 0.0384 0.0384
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0305 0.0565 0.0565
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0182 0.0116 0.0133
Loa Loa (eye worm) hypothetical protein 0.0318 0.0612 0.0612
Echinococcus multilocularis Glutaredoxin protein 5 0.038 0.0839 0.1402
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0644 0.1801 0.3284
Loa Loa (eye worm) TK protein kinase 0.0792 0.234 0.234
Brugia malayi Temporarily assigned gene name protein 59 0.0318 0.0612 0.0612
Trichomonas vaginalis AGC family protein kinase 0.0575 0.1547 0.553
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.022 0.0254 0.0901
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Giardia lamblia Kinase, AGC AKT 0.0355 0.0747 0.3022
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0798 0.1455
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0692 0.1976 0.3303
Onchocerca volvulus 0.0568 0.1523 0.3327
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0303 0.0556 0.2246
Echinococcus multilocularis tyrosine protein kinase Srms 0.0466 0.115 0.1923
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0251 0.0366 0.1344
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0253 0.0373 0.1504
Schistosoma mansoni protein kinase 0.133 0.4301 0.7843
Echinococcus granulosus serine:threonine protein kinase 0.0346 0.0714 0.0813
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0329 0.0653 0.0653
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0709 0.1292
Entamoeba histolytica protein kinase, putative 0.0309 0.0579 0.1553
Echinococcus multilocularis protein kinase c epsilon type 0.0644 0.1801 0.301
Echinococcus granulosus casein kinase i 0.0329 0.0653 0.0743
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Schistosoma mansoni serine/threonine protein kinase 0.0443 0.1066 0.1943
Echinococcus multilocularis protein tyrosine kinase 0.0913 0.2782 0.465
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0345 0.0709 0.1185
Echinococcus granulosus nervana 2 0.038 0.0839 0.0956
Loa Loa (eye worm) hypothetical protein 0.027 0.0437 0.0437
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0251 0.0366 0.1301
Echinococcus granulosus protein kinase shaggy 0.0391 0.0877 0.0999
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0798 0.1455
Loa Loa (eye worm) TK/ABL protein kinase 0.0467 0.1153 0.1153
Echinococcus multilocularis mitogen activated protein kinase 14 0.0485 0.1219 0.2037
Echinococcus granulosus raf serine:threonine protein kinase 0.0252 0.0372 0.0423
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0303 0.0556 0.0556
Echinococcus multilocularis dual specificity 0.0369 0.0796 0.1331
Echinococcus granulosus dual specificity 0.0369 0.0796 0.0907
Brugia malayi Protein kinase domain containing protein 0.0468 0.1157 0.1157
Echinococcus granulosus casein kinase I alpha 0.0329 0.0653 0.0743
Trypanosoma cruzi casein kinase, putative 0.0329 0.0653 0.2639
Loa Loa (eye worm) hypothetical protein 0.0556 0.1478 0.1478
Echinococcus multilocularis mitogen activated protein kinase 14 0.0485 0.1219 0.2037
Trichomonas vaginalis CAMK family protein kinase 0.054 0.142 0.5077
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0305 0.0565 0.0944
Echinococcus multilocularis Immunoglobulin 0.0209 0.0215 0.0359
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0443 0.1066 0.1214
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0371 0.0805 0.3258
Loa Loa (eye worm) hypothetical protein 0.0209 0.0215 0.0215
Entamoeba histolytica protein kinase, putative 0.0251 0.0366 0.0978
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0373 0.1326
Schistosoma mansoni protein kinase 0.026 0.0398 0.0727
Loa Loa (eye worm) AGC/PKA protein kinase 0.0303 0.0556 0.0556
Plasmodium vivax calcium-dependent protein kinase, putative 0.0305 0.0565 0.4733
Trypanosoma brucei protein kinase, putative 0.022 0.0254 0.0901
Echinococcus granulosus roundabout 2 0.036 0.0763 0.0869
Echinococcus multilocularis casein kinase i 0.0329 0.0653 0.1091
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0246 0.0348 0.0396
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.026 0.0398 0.0666
Echinococcus granulosus Protein kinase C brain isozyme 0.0766 0.2246 0.2558
Brugia malayi Protein kinase domain containing protein 0.0251 0.0366 0.0366
Trypanosoma cruzi cdc2-related kinase 3 0.0361 0.0766 0.3101
Schistosoma mansoni serine/threonine protein kinase 0.0361 0.0766 0.1397
Trichomonas vaginalis CAMK family protein kinase 0.0384 0.0851 0.3039
Loa Loa (eye worm) hypothetical protein 0.0163 0.0047 0.0047
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0225 0.0272 0.0496
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Toxoplasma gondii aurora kinase 0.0443 0.1066 0.3934
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.1157 0.211
Echinococcus granulosus mitogen activated protein kinase 0.0253 0.0373 0.0425
Brugia malayi Protein kinase domain containing protein 0.0214 0.0234 0.0234
Echinococcus multilocularis 0.0405 0.0929 0.1552
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0559 0.1489 0.1696
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Echinococcus granulosus Glutaredoxin protein 5 0.038 0.0839 0.0956
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Schistosoma mansoni kinase 0.0883 0.2672 0.4873
Onchocerca volvulus 0.1137 0.3598 0.8381
Trypanosoma cruzi casein kinase, putative 0.0329 0.0653 0.2639
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0467 0.1153 0.1928
Schistosoma mansoni protein kinase 0.026 0.0398 0.0727
Loa Loa (eye worm) hypothetical protein 0.0303 0.0556 0.0556
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0255 0.0383 0.1363
Echinococcus multilocularis 0.0371 0.0805 0.1346
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.027 0.0437 0.1762
Schistosoma mansoni serine/threonine protein kinase 0.0808 0.2398 0.4373
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Entamoeba histolytica protein kinase, putative 0.0371 0.0805 0.2161
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.077 0.2261 0.3779
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0373 0.1326
Schistosoma mansoni tyrosine kinase 0.0349 0.0723 0.1318
Echinococcus granulosus titin 0.0198 0.0175 0.0199
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0734 0.2127 0.3555
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Trichomonas vaginalis AGC family protein kinase 0.0414 0.0961 0.3432
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0443 0.1066 0.2863
Echinococcus multilocularis serine threonine protein kinase 0.0638 0.1776 0.2969
Echinococcus granulosus dual specificity testis-specific protein kinase 0.054 0.1422 0.1619
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0213 0.0228 0.0381
Entamoeba histolytica protein kinase, putative 0.0391 0.0877 0.2355
Schistosoma mansoni serine/threonine protein kinase 0.108 0.3389 0.6179
Loa Loa (eye worm) TK/FAK protein kinase 0.0923 0.2816 0.2816
Echinococcus multilocularis mitogen activated protein kinase 11 0.0485 0.1219 0.2037
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0619 0.1708 0.2856
Plasmodium falciparum glycogen synthase kinase 3 0.0391 0.0877 0.736
Entamoeba histolytica protein kinase, putative 0.0246 0.0348 0.0929
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0222 0.0262 0.0262
Entamoeba histolytica PH domain containing protein kinase, putative 0.0328 0.0646 0.1733
Trypanosoma cruzi p21-activated kinase 3, putative 0.0163 0.0047 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0361 0.0766 0.3101
Echinococcus multilocularis serine:threonine protein kinase N2 0.0399 0.0906 0.1515
Echinococcus granulosus serine:threonine protein kinase 3 0.0785 0.2315 0.2636
Entamoeba histolytica protein kinase domain containing protein 0.0369 0.0796 0.2137
Loa Loa (eye worm) AUR protein kinase 0.0443 0.1066 0.1066
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0253 0.0373 0.1504
Plasmodium falciparum casein kinase 2, alpha subunit 0.0303 0.0557 0.4664
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0679 0.1926 0.322
Brugia malayi hypothetical protein 0.0256 0.0384 0.0384
Onchocerca volvulus 0.0256 0.0384 0.0551
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0251 0.0366 0.1475
Entamoeba histolytica protein kinase, putative 0.0917 0.2795 0.7522
Echinococcus granulosus casein kinase I alpha 0.0329 0.0653 0.0743
Loa Loa (eye worm) hypothetical protein 0.0939 0.2874 0.2874
Brugia malayi Protein kinase domain containing protein 0.0256 0.0384 0.0384
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0251 0.0366 0.1475
Loa Loa (eye worm) hypothetical protein 0.0439 0.1054 0.1054
Echinococcus granulosus mitogen activated protein kinase 3 0.0253 0.0373 0.0425
Schistosoma mansoni ephrin receptor 0.0167 0.006 0.011
Brugia malayi Variant SH3 domain containing protein 0.0161 0.0037 0.0037
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0213 0.0228 0.026
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0233 0.0301 0.1211
Echinococcus multilocularis casein kinase ii subunit alpha 0.0303 0.0557 0.093
Schistosoma mansoni ste20-related kinase 0.0626 0.1735 0.3163
Loa Loa (eye worm) hypothetical protein 0.0427 0.1009 0.1009
Schistosoma mansoni serine/threonine-protein kinase 0.0502 0.1281 0.2336
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0665 0.1875 0.1875
Entamoeba histolytica protein kinase, putative 0.0213 0.0228 0.0608
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.1157 0.211
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0159 0.0033 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0618 0.1707 0.459
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0512 0.1317 0.1501
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0213 0.0228 0.026
Schistosoma mansoni vav2 0.0285 0.0492 0.0898
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0163 0.0047 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0329 0.0653 0.0653
Echinococcus multilocularis epidermal growth factor receptor 0.1083 0.3401 0.5686
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0206 0.0204 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0619 0.1708 0.3115
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0017 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0209 0.0215 0.0391
Brugia malayi map kinase activated protein kinase protein 2 0.1208 0.3856 0.3856
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0373 0.1326
Brugia malayi C1-like domain containing protein 0.0665 0.1875 0.1875
Echinococcus granulosus mitogen activated protein kinase 14 0.0485 0.1219 0.1388
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.0805 0.2161
Echinococcus multilocularis twitchin 0.0155 0.0017 0.0029
Echinococcus granulosus tyrosine protein kinase Fyn 0.0559 0.1489 0.1696
Echinococcus granulosus CDC7 cell division cycle 7 0.0214 0.0234 0.0266
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0184 0.0123 0.0431
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0361 0.0766 0.0766
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0159 0.0033 0.0108
Loa Loa (eye worm) hypothetical protein 0.0305 0.0565 0.0565
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0567 0.1518 0.1518
Echinococcus granulosus serine:threonine protein kinase N2 0.0911 0.2772 0.3157
Echinococcus multilocularis Immunoglobulin 0.0209 0.0215 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Brugia malayi serine/threonine-protein kinase 6 0.0443 0.1066 0.1066
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0613 0.1685 0.2817
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Echinococcus multilocularis dual specificity protein kinase clk2 0.0468 0.1157 0.1934
Echinococcus multilocularis tyrosine protein kinase HCK 0.0334 0.0669 0.1119
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0345 0.0709 0.1185
Entamoeba histolytica protein kinase, putative 0.0193 0.0155 0.0411
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0903 0.2744 0.4587
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.038 0.0839 0.1402
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0163 0.0047 0.0179
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.038 0.0839 0.0956
Plasmodium falciparum protein kinase, putative 0.022 0.0254 0.2118
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0305 0.0565 0.4733
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0485 0.1219 0.4938
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.1826 0.3329
Plasmodium vivax glycogen synthase kinase 3, putative 0.0391 0.0877 0.736
Brugia malayi ephrin receptor 1 precursor 0.0216 0.0241 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0618 0.1707 0.3112
Brugia malayi RhoGAP domain containing protein 0.0261 0.0402 0.0402
Brugia malayi Protein kinase domain containing protein 0.0923 0.2816 0.2816
Brugia malayi serine/threonine-protein kinase PAK 7 0.0709 0.2037 0.2037
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Plasmodium falciparum calcium-dependent protein kinase 3 0.0305 0.0565 0.4733
Echinococcus granulosus cGMP dependent protein kinase 1 0.0345 0.0709 0.0807
Onchocerca volvulus Serine\/threonine kinase homolog 0.0827 0.2465 0.5622
Echinococcus multilocularis serine:threonine protein kinase N2 0.0512 0.1317 0.2202
Brugia malayi hypothetical protein 0.0174 0.0085 0.0085
Loa Loa (eye worm) CAMK/PIM protein kinase 0.108 0.3389 0.3389
Echinococcus granulosus cGMP dependent protein kinase 1 0.0345 0.0709 0.0807
Schistosoma mansoni tyrosine kinase 0.0349 0.0723 0.1318
Loa Loa (eye worm) hypothetical protein 0.0568 0.1523 0.1523
Entamoeba histolytica cell division protein kinase 2, putative 0.0361 0.0766 0.2057
Onchocerca volvulus Tyrosine kinase homolog 0.1319 0.4263 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0559 0.1489 0.1696
Trichomonas vaginalis CMGC family protein kinase 0.0214 0.0234 0.0828
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0206 0.0204 0.0341
Echinococcus multilocularis casein kinase I delta 0.0329 0.0653 0.1091
Loa Loa (eye worm) hypothetical protein 0.0318 0.0612 0.0612
Brugia malayi hypothetical protein 0.0679 0.1926 0.1926
Schistosoma mansoni serine/threonine-protein kinase 0.0502 0.1281 0.2336
Schistosoma mansoni titin 0.0198 0.0175 0.0319
Brugia malayi Protein kinase domain containing protein 0.1184 0.377 0.377
Trichomonas vaginalis STE family protein kinase 0.0414 0.0961 0.3432
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0391 0.0877 0.0877
Brugia malayi Immunoglobulin I-set domain containing protein 0.1518 0.4988 0.4988
Echinococcus granulosus cyclin dependent kinase 5 0.0361 0.0766 0.0873
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.108 0.3389 0.5664
Schistosoma mansoni serine/threonine protein kinase 0.0692 0.1976 0.3604
Schistosoma mansoni atypical protein kinase C 0.0914 0.2785 0.5078
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1098 0.3454 0.5774
Brugia malayi Protein kinase domain containing protein 0.0917 0.2795 0.2795
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0618 0.1707 0.1944
Schistosoma mansoni nck2/grb4 0.0225 0.0272 0.0496
Echinococcus multilocularis mitogen activated protein kinase 0.0253 0.0373 0.0623
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0766 0.2246 0.3754
Brugia malayi SH2 domain containing protein 0.1059 0.3314 0.3314
Plasmodium vivax protein kinase Crk2 0.0361 0.0766 0.6429
Brugia malayi Protein kinase domain containing protein 0.0246 0.0348 0.0348
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0618 0.1707 0.1707
Echinococcus multilocularis 0.0471 0.1168 0.1953
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0593 0.1082
Schistosoma mansoni serine/threonine protein kinase 0.0995 0.3081 0.5618
Brugia malayi SRC-1 0.0559 0.1489 0.1489
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0499 0.1271 0.1271
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0827 0.2465 0.4121
Brugia malayi cell division control protein 2 homolog 0.0361 0.0766 0.0766
Brugia malayi Casein kinase II, alpha chain 0.0303 0.0557 0.0557
Brugia malayi Fes/CIP4 homology domain containing protein 0.0322 0.0627 0.0627
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Giardia lamblia Kinase, CMGC CDK 0.0361 0.0766 0.3101
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0305 0.0565 0.2014
Brugia malayi Pleckstrin Homology Domain 0.0153 0.0011 0.0011
Trypanosoma brucei rac serine-threonine kinase, putative 0.0917 0.2795 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0559 0.1489 0.2489
Echinococcus multilocularis protein kinase shaggy 0.0391 0.0877 0.1466
Brugia malayi Variant SH3 domain containing protein 0.0261 0.0402 0.0402
Echinococcus multilocularis cyclin dependent kinase 1 0.0361 0.0766 0.1281
Loa Loa (eye worm) hypothetical protein 0.0738 0.2141 0.2141
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0261 0.0402 0.0458
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0369 0.0796 0.3221
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0536 0.1406 0.1406
Schistosoma mansoni tyrosine kinase 0.1184 0.377 0.6875
Echinococcus granulosus cGMP dependent protein kinase 0.0345 0.0709 0.0807
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0805 0.1468
Loa Loa (eye worm) hypothetical protein 0.0366 0.0786 0.0786
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0559 0.1489 0.2489
Schistosoma mansoni tyrosine kinase 0.0814 0.242 0.4414
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0477 0.1191 0.4824
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0253 0.0373 0.1326
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0477 0.1191 1
Brugia malayi Protein kinase domain containing protein 0.1375 0.4465 0.4465
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0426 0.1515
Schistosoma mansoni serine/threonine protein kinase 0.0827 0.2465 0.4496
Brugia malayi Protein kinase domain containing protein 0.0613 0.1686 0.1686
Onchocerca volvulus 0.0214 0.0234 0.0186
Echinococcus granulosus nervana 2 0.038 0.0839 0.0956
Brugia malayi Protein kinase domain containing protein 0.1275 0.41 0.41
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Echinococcus multilocularis myotubularin protein 13 0.0153 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0253 0.0372 0.0372
Echinococcus granulosus rho-associated protein kinase 1 0.0995 0.3081 0.3509
Brugia malayi Kinase associated domain 1 family protein 0.0273 0.0446 0.0446
Entamoeba histolytica protein kinase, putative 0.026 0.0398 0.1066
Schistosoma mansoni serine/threonine protein kinase 0.1208 0.3856 0.7031
Echinococcus multilocularis N chimaerin 0.0261 0.0402 0.0672
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0371 0.0805 0.2873
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0318 0.0612 0.0612
Giardia lamblia Kinase, NEK 0.0414 0.0961 0.3891
Loa Loa (eye worm) thyroid receptor interactor 0.0322 0.0627 0.0627
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.027 0.0437 0.1762
Echinococcus granulosus epidermal growth factor receptor 0.1083 0.3401 0.3874
Onchocerca volvulus 0.0256 0.0384 0.0551
Onchocerca volvulus 0.0318 0.0612 0.1106
Loa Loa (eye worm) SRC-1 0.0559 0.1489 0.1489
Echinococcus granulosus dual specificity 0.0369 0.0796 0.0907
Brugia malayi hypothetical protein 0.0318 0.0612 0.0612
Entamoeba histolytica protein kinase, putative 0.0218 0.0245 0.0654
Entamoeba histolytica hypothetical protein 0.0371 0.0805 0.2161
Trypanosoma brucei protein kinase, putative 0.0253 0.0373 0.1326
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0261 0.0402 0.0733
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0175 0.0319
Schistosoma mansoni tyrosine kinase 0.0734 0.2127 0.3878
Onchocerca volvulus 0.0256 0.0384 0.0551
Leishmania major protein kinase, putative 0.022 0.0254 0.1022
Echinococcus multilocularis dual specificity 0.0371 0.0805 0.1345
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1275 0.41 0.41
Trichomonas vaginalis AGC family protein kinase 0.0303 0.0556 0.1981
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0244 0.0342 0.1258
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0567 0.1518 0.2537
Giardia lamblia Kinase, NEK 0.0414 0.0961 0.3891
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Echinococcus granulosus protein kinase C gamma type 0.0638 0.1776 0.2023
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0361 0.0766 0.0766
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.022 0.0254 0.0931
Trypanosoma brucei cdc2-related kinase 3 0.0361 0.0766 0.2735
Onchocerca volvulus 0.0256 0.0384 0.0551
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Trichomonas vaginalis AGC family protein kinase 0.0443 0.1066 0.3807
Echinococcus multilocularis protein kinase c iota type 0.0895 0.2717 0.4541
Echinococcus multilocularis rho associated protein kinase 0.0995 0.3081 0.515
Echinococcus granulosus serine:threonine protein kinase N2 0.0399 0.0906 0.1032
Trypanosoma brucei protein kinase, putative 0.0391 0.0877 0.3131
Loa Loa (eye worm) hypothetical protein 0.0627 0.1737 0.1737
Echinococcus granulosus tyrosine protein kinase Srms 0.1103 0.3473 0.3956
Brugia malayi Stress-activated protein kinase jnk-1 0.0808 0.2398 0.2398
Plasmodium falciparum protein serine/threonine kinase-1 0.0468 0.1157 0.9718
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0627 0.1737 0.1978
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0468 0.1157 0.4273
Onchocerca volvulus 0.0214 0.0234 0.0186
Giardia lamblia Kinase, CMGC CDK 0.0361 0.0766 0.3101
Plasmodium falciparum NIMA related kinase 1 0.0414 0.0961 0.8066
Loa Loa (eye worm) AGC/PKN protein kinase 0.0911 0.2772 0.2772
Trichomonas vaginalis CMGC family protein kinase 0.0361 0.0766 0.2735
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0559 0.1489 0.2489
Echinococcus granulosus calcium dependent protein kinase 0.0209 0.0213 0.0243
Loa Loa (eye worm) hypothetical protein 0.0225 0.0272 0.0272
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.026 0.0398 0.0454
Loa Loa (eye worm) AUR protein kinase 0.0443 0.1066 0.1066
Entamoeba histolytica casein kinase 1, putative 0.0329 0.0653 0.1751
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0929
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0305 0.0565 0.0944
Brugia malayi Immunoglobulin I-set domain containing protein 0.0253 0.0372 0.0372
Entamoeba histolytica protein kinase, putative 0.0917 0.2795 0.7522
Schistosoma mansoni protein kinase 0.0405 0.0929 0.1693
Brugia malayi Variant SH3 domain containing protein 0.0225 0.0272 0.0272
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0619 0.1708 0.2856
Loa Loa (eye worm) hypothetical protein 0.0273 0.0446 0.0446
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0346 0.0715 0.1195
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0414 0.0961 0.8066
Entamoeba histolytica protein kinase, putative 0.0443 0.1066 0.2863
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0415 0.0963 0.161
Brugia malayi Tyrosine-protein kinase abl-1 0.0429 0.1017 0.1017
Brugia malayi Protein kinase domain containing protein 0.0494 0.1252 0.1252
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0253 0.0373 0.1504
Leishmania major protein kinase A catalytic subunit isoform 2 0.0303 0.0556 0.2246
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0003 0.0005
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0443 0.1066 0.1781
Brugia malayi Immunoglobulin I-set domain containing protein 0.0198 0.0175 0.0175
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0679 0.1926 0.2194
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.1462 0.4784 0.8724
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Loa Loa (eye worm) TK protein kinase 0.0927 0.2833 0.2833
Entamoeba histolytica serine/threonine protein kinase, putative 0.027 0.0437 0.1169
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0047 0.0085
Brugia malayi Protein kinase domain 0.026 0.0398 0.0398
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0827 0.2465 1
Echinococcus granulosus Immunoglobulin 0.0209 0.0215 0.0244
Loa Loa (eye worm) hypothetical protein 0.021 0.0218 0.0218
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.022 0.0254 0.1022
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0255 0.0383 0.1025
Giardia lamblia Kinase, CMGC CLK 0.0468 0.1157 0.4688
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Onchocerca volvulus 0.0198 0.0175 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0305 0.0565 0.0565
Brugia malayi casein kinase I 0.0329 0.0653 0.0653
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0303 0.0556 0.2246
Schistosoma mansoni protein kinase 0.133 0.4301 0.7843
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0373 0.1326
Echinococcus granulosus dual specificity protein kinase clk2 0.0468 0.1157 0.1318
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Entamoeba histolytica protein kinase, putative 0.0305 0.0565 0.1514
Echinococcus multilocularis serine:threonine protein kinase 3 0.0785 0.2315 0.3869
Plasmodium vivax serine/threonine protein kinase, putative 0.0251 0.0366 0.3058
Schistosoma mansoni tyrosine kinase 0.0559 0.1489 0.2716
Brugia malayi Egg laying defective protein 4 0.0345 0.0709 0.0709
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0692 0.1976 0.2251
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0391 0.0877 0.0999
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0303 0.0556 0.4657
Echinococcus multilocularis casein kinase I alpha 0.0329 0.0653 0.1091
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0163 0.0047 0.0047
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2558 0.878 1
Echinococcus multilocularis rac serine:threonine kinase 0.0502 0.1281 0.2141
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0361 0.0766 0.2826
Brugia malayi Variant SH3 domain containing protein 0.0225 0.0272 0.0272
Echinococcus multilocularis casein kinase I alpha 0.0329 0.0653 0.1091
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.038 0.0837 0.3389
Schistosoma mansoni serine/threonine protein kinase 0.0361 0.0766 0.1397
Entamoeba histolytica protein kinase , putative 0.0443 0.1066 0.2863
Schistosoma mansoni protein kinase 0.0193 0.0155 0.0283
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0303 0.0556 0.1981
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0305 0.0565 0.0944
Onchocerca volvulus 0.0593 0.1613 0.3547
Echinococcus multilocularis dual specificity testis specific protein kinase 0.054 0.1422 0.2376
Trypanosoma cruzi casein kinase, putative 0.0329 0.0653 0.2639
Plasmodium vivax tyrosine kinase-like protein, putative 0.0244 0.0342 0.286
Echinococcus multilocularis serine:threonine protein kinase N2 0.0911 0.2772 0.4634
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0318 0.0612 0.1115
Loa Loa (eye worm) hypothetical protein 0.0275 0.0453 0.0453
Loa Loa (eye worm) TK/INSR protein kinase 0.1184 0.377 0.377
Echinococcus multilocularis casein kinase I gamma 0.0651 0.1826 0.3052
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.026 0.0398 0.0666
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0209 0.0215 0.0359
Plasmodium falciparum cGMP-dependent protein kinase 0.0345 0.0709 0.5944
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0613 0.1685 0.1919
Brugia malayi Protein kinase domain containing protein 0.0361 0.0766 0.0766
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0369 0.0796 0.0796
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0256 0.0384 0.1027
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0827 0.2465 0.2808
Brugia malayi putative serine/threonine kinase SADA gamma 0.027 0.0437 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.078 0.2294 0.4184
Leishmania major protein kinase, putative 0.0468 0.1157 0.4688
Loa Loa (eye worm) hypothetical protein 0.0439 0.1054 0.1054
Plasmodium falciparum calcium-dependent protein kinase 1 0.0305 0.0565 0.4733
Schistosoma mansoni ephrin receptor 0.0321 0.0621 0.1132
Giardia lamblia Kinase, AGC PKA 0.0477 0.1191 0.4824
Echinococcus granulosus epidermal growth factor receptor 0.1654 0.5484 0.6246
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0567 0.1518 0.1729
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0559 0.1489 0.2489
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0443 0.1066 0.2863
Echinococcus multilocularis ephrin type A receptor 4 A 0.0321 0.0621 0.1038
Echinococcus multilocularis PAK box P21 Rho binding 0.0193 0.0155 0.0259
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0182 0.0116 0.0194
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0258 0.0391 0.0446
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0559 0.1489 0.1696
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Loa Loa (eye worm) hypothetical protein 0.0427 0.1009 0.1009
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0371 0.0805 0.3258
Giardia lamblia Aurora kinase 0.0443 0.1066 0.4316
Schistosoma mansoni tyrosine kinase 0.1083 0.3401 0.6202
Plasmodium falciparum serine/threonine protein kinase 0.0251 0.0366 0.3058
Echinococcus multilocularis CDC7 cell division cycle 7 0.0214 0.0234 0.0391
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0303 0.0557 0.4664
Brugia malayi Protein kinase c protein 2 0.0351 0.0731 0.0731
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Entamoeba histolytica protein kinase, putative 0.0228 0.0285 0.0759
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.027 0.0437 0.1554
Echinococcus granulosus casein kinase I delta 0.0329 0.0653 0.0743
Brugia malayi P38 map kinase family protein 2 0.0485 0.1219 0.1219
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0468 0.1157 0.4688
Brugia malayi Sex muscle abnormal protein 5 0.0225 0.0272 0.0272
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0318 0.0612 0.2473
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0468 0.1157 0.4688
Loa Loa (eye worm) protein kinase domain-containing protein 0.0651 0.1826 0.1826
Echinococcus multilocularis tyrosine protein kinase shark 0.0699 0.2002 0.3346
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0679 0.1926 0.1926
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0303 0.0557 0.0557
Trypanosoma brucei polo-like protein kinase 0.0827 0.2465 0.882
Onchocerca volvulus 0.0256 0.0384 0.0551
Loa Loa (eye worm) CAMK/PHK protein kinase 0.05 0.1274 0.1274
Plasmodium falciparum calcium-dependent protein kinase 4 0.0305 0.0565 0.4733
Echinococcus granulosus ephrin type A receptor 4 A 0.0321 0.0621 0.0707
Brugia malayi Immunoglobulin I-set domain containing protein 0.0792 0.234 0.234
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1059 0.3314 0.3774
Trichomonas vaginalis AGC family protein kinase 0.0443 0.1066 0.3807
Trichomonas vaginalis STE family protein kinase 0.026 0.0398 0.1418
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0827 0.2465 0.2465
Loa Loa (eye worm) TK/EGFR protein kinase 0.1654 0.5484 0.5484
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0575 0.1547 0.1547
Schistosoma mansoni serine/threonine protein kinase 0.0512 0.1317 0.2402
Echinococcus multilocularis activin receptor type 0.022 0.0254 0.0425
Echinococcus granulosus tyrosine protein kinase ABL1 0.0467 0.1153 0.1313
Entamoeba histolytica protein kinase, putative 0.0334 0.0669 0.1795
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.0557 0.1492
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0303 0.0556 0.2246
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0559 0.1489 0.2489
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Toxoplasma gondii AGC kinase 0.0892 0.2705 1
Entamoeba histolytica protein kinase, putative 0.0218 0.0245 0.0654
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0253 0.0373 0.1504
Loa Loa (eye worm) AGC/NDR protein kinase 0.0512 0.1317 0.1317
Loa Loa (eye worm) hypothetical protein 0.0209 0.0215 0.0215
Brugia malayi p70 ribosomal S6 kinase beta 0.0892 0.2705 0.2705
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0391 0.0877 0.0877
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0618 0.1707 0.2853
Schistosoma mansoni serine/threonine protein kinase 0.0679 0.1926 0.3513
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus multilocularis myosin iiia 0.0255 0.0383 0.0641
Echinococcus granulosus NCK adaptor protein 0.0225 0.0272 0.031
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0502 0.1281 0.519
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.133 0.4301 0.719
Entamoeba histolytica protein kinase, putative 0.0892 0.2705 0.7278
Echinococcus granulosus casein kinase ii subunit alpha 0.0303 0.0557 0.0634
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0348 0.1236
Echinococcus multilocularis nervana 2 0.038 0.0839 0.1402
Echinococcus granulosus phosphorylase kinase gamma subunit 0.05 0.1274 0.1451
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0466 0.115 0.1923
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0361 0.0766 0.3101
Schistosoma mansoni serine/threonine kinase 0.0512 0.1317 0.2402
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0391 0.0877 0.1466
Trypanosoma cruzi casein kinase, putative 0.0329 0.0653 0.2639
Schistosoma mansoni tyrosine kinase 0.0913 0.2782 0.5072
Schistosoma mansoni protein kinase 0.1098 0.3454 0.6299
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1275 0.41 0.41
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0198 0.0175 0.0175
Brugia malayi Protein kinase domain containing protein 0.0256 0.0384 0.0384
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0305 0.0565 0.0643
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0159 0.0033 0.0108
Echinococcus multilocularis tyrosine protein kinase Blk 0.0466 0.115 0.1923
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0267 0.0426 0.0712
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0512 0.1317 0.2202
Schistosoma mansoni rap gtpase-activating protein 0.0318 0.0612 0.1115
Echinococcus granulosus tyrosine protein kinase Src42A 0.0346 0.0715 0.0814
Schistosoma mansoni serine/threonine kinase 0.054 0.142 0.259
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0653 0.119
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0468 0.1157 0.4134
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Plasmodium vivax unspecified product 0.0303 0.0557 0.4664
Toxoplasma gondii histone kinase SNF1, putative 0.027 0.0437 0.1606
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0556 0.1014
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Echinococcus multilocularis serine:threonine protein kinase 0.0346 0.0714 0.1193
Echinococcus multilocularis casein kinase I alpha 0.0329 0.0653 0.1091
Plasmodium falciparum calcium-dependent protein kinase 2 0.0305 0.0565 0.4733
Brugia malayi protein kinase C3,putative 0.048 0.1202 0.1202
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0734 0.2127 0.2422
Loa Loa (eye worm) CDC7 protein kinase 0.0214 0.0234 0.0234
Brugia malayi protein kinase C II. 0.0644 0.1801 0.1801
Trichomonas vaginalis STE family protein kinase 0.026 0.0398 0.1418
Brugia malayi Protein kinase domain containing protein 0.0371 0.0805 0.0805
Echinococcus granulosus myotubularin protein 13 0.0153 0.0011 0.0013
Schistosoma mansoni nephrin 0.0311 0.0586 0.1069
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Echinococcus granulosus mitogen activated protein kinase 11 0.0485 0.1219 0.1388
Echinococcus multilocularis dual specificity 0.0369 0.0796 0.1331
Plasmodium falciparum casein kinase 1 0.0329 0.0653 0.5471
Schistosoma mansoni protein kinase 0.0443 0.1066 0.1943
Trichomonas vaginalis CK1 family protein kinase 0.0329 0.0653 0.2328
Echinococcus granulosus tyrosine protein kinase Src42A 0.0559 0.1489 0.1696
Loa Loa (eye worm) hypothetical protein 0.0264 0.0415 0.0415
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0228 0.0416
Plasmodium vivax casein kinase 1, putative 0.0329 0.0653 0.5471
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0415 0.0963 0.1097
Loa Loa (eye worm) TK protein kinase 0.0466 0.115 0.115
Trypanosoma cruzi Protein kinase B 0.0502 0.1281 0.519
Echinococcus granulosus serine:threonine kinase SAD 1 0.027 0.0437 0.0497
Leishmania major protein kinase A catalytic subunit 0.0303 0.0556 0.2246
Echinococcus granulosus N chimaerin 0.0261 0.0402 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.0619 0.1708 0.3115
Schistosoma mansoni cell adhesion molecule 0.0301 0.0549 0.1001
Echinococcus granulosus protein kinase 0.0405 0.0929 0.1058
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0559 0.1489 0.2489
Plasmodium falciparum calcium-dependent protein kinase 5 0.0305 0.0565 0.4733
Loa Loa (eye worm) hypothetical protein 0.0253 0.0372 0.0372
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0633
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0892 0.2705 0.2705
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0213 0.0228 0.0382
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.026 0.0398 0.0454
Loa Loa (eye worm) AGC/PKG protein kinase 0.0345 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.0153 0.0011 0.0011
Echinococcus granulosus NDR protein kinase 0.0512 0.1317 0.1501
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0267 0.0426 0.0485
Loa Loa (eye worm) TK/ROR protein kinase 0.0182 0.0116 0.0116
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1098 0.3454 0.3454
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0414 0.0961 0.3546
Brugia malayi Protein kinase domain containing protein 0.05 0.1274 0.1274
Brugia malayi Protein kinase domain containing protein 0.0185 0.0128 0.0128
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0559 0.1489 0.2489
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0369 0.0796 0.2936
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0244 0.0342 0.286
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0466 0.115 0.131
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0391 0.0877 0.355
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0468 0.1157 0.4688
Entamoeba histolytica protein kinase domain containing protein 0.0391 0.0877 0.2355
Loa Loa (eye worm) hypothetical protein 0.0316 0.0605 0.0605
Schistosoma mansoni tyrosine kinase 0.0335 0.0672 0.1225
Trichomonas vaginalis CMGC family protein kinase 0.0468 0.1157 0.4134
Trichomonas vaginalis CK1 family protein kinase 0.0329 0.0653 0.2328
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1208 0.3856 0.6445
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0261 0.0402 0.0672
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0318 0.0612 0.2473
Schistosoma mansoni hypothetical protein 0.0273 0.0446 0.0814
Loa Loa (eye worm) hypothetical protein 0.0157 0.0023 0.0023
Echinococcus multilocularis aurora kinase A 0.0443 0.1066 0.1781
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0929
Trichomonas vaginalis AGC family protein kinase 0.0443 0.1066 0.3807
Echinococcus multilocularis roundabout 2 0.036 0.0763 0.1275
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0808 0.2398 0.2398
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0161 0.0037 0.0037
Echinococcus multilocularis serine:threonine protein kinase 0.0346 0.0714 0.1193
Schistosoma mansoni protein kinase 0.0329 0.0653 0.119
Brugia malayi serine/threonine protein kinase 6 0.0443 0.1066 0.1066
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1058 0.3308 0.3308
Trypanosoma cruzi casein kinase II, putative 0.0303 0.0557 0.225
Trypanosoma cruzi casein kinase, putative 0.0329 0.0653 0.2639
Brugia malayi Protein kinase domain containing protein 0.0512 0.1317 0.1317
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0228 0.0285 0.0759
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1516 0.4979 0.5671
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0253 0.0373 0.1504
Plasmodium falciparum serine/threonine protein kinase KIN 0.027 0.0437 0.3653
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0318 0.0612 0.1115
Trichomonas vaginalis CMGC family protein kinase 0.0214 0.0234 0.0828
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0477 0.1191 0.199
Brugia malayi Protein kinase domain containing protein 0.1275 0.41 0.41
Schistosoma mansoni serine/threonine protein kinase 0.0613 0.1686 0.3074
Echinococcus granulosus hypothetical protein 0.0371 0.0805 0.0917
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0477 0.1191 1
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Brugia malayi Protein kinase domain containing protein 0.0575 0.1547 0.1547
Entamoeba histolytica protein kinase 2, putative 0.0477 0.1191 0.32
Schistosoma mansoni serine/threonine protein kinase 0.0692 0.1976 0.3604
Echinococcus multilocularis cyclin dependent kinase 0.0361 0.0766 0.1281
Echinococcus granulosus expressed protein 0.0251 0.0366 0.0417
Schistosoma mansoni protein kinase C mu 0.0665 0.1875 0.3419
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0437 0.0796
Entamoeba histolytica protein kinase domain containing protein 0.0391 0.0877 0.2355
Echinococcus multilocularis cyclin dependent kinase 5 0.0361 0.0766 0.1281
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0349 0.0723 0.1318
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0348 0.1236
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0441 0.1058 0.1205
Schistosoma mansoni adapter molecule crk 0.0225 0.0272 0.0496
Loa Loa (eye worm) hypothetical protein 0.037 0.0801 0.0801
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0644 0.1801 0.1801
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0785 0.2315 0.2315
Trichomonas vaginalis STE family protein kinase 0.026 0.0398 0.1418
Schistosoma mansoni tyrosine kinase 0.0231 0.0293 0.0534
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Echinococcus multilocularis nervana 2 0.038 0.0839 0.1402
Plasmodium vivax protein kinase, putative 0.017 0.0072 0.0583
Echinococcus multilocularis serine:threonine protein kinase 38 0.0512 0.1317 0.2202
Trypanosoma brucei casein kinase I, isoform 2 0.0329 0.0653 0.2328
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.027 0.0437 0.3653
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0426 0.1515
Schistosoma mansoni protein kinase 0.0723 0.2089 0.3808
Trichomonas vaginalis AGC family protein kinase 0.0512 0.1317 0.4709
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0369 0.0796 0.2841
Entamoeba histolytica casein kinase, putative 0.0329 0.0653 0.1751
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0318 0.0612 0.2181
Echinococcus granulosus Vam6:Vps39 protein 0.0318 0.0612 0.0697
Brugia malayi phosphoinositide-dependent protein kinase I 0.0246 0.0348 0.0348
Brugia malayi Protein kinase domain containing protein 0.0256 0.0384 0.0384
Trypanosoma cruzi cdc2-related kinase 3 0.0361 0.0766 0.3101
Brugia malayi Protein kinase domain containing protein 0.108 0.3389 0.3389
Brugia malayi casein kinase 1, delta 0.0329 0.0653 0.0653
Toxoplasma gondii AGC kinase 0.0303 0.0556 0.2047
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1025 0.3188 0.3188
Loa Loa (eye worm) hypothetical protein 0.0371 0.0805 0.0805
Brugia malayi Protein kinase domain containing protein 0.0861 0.2592 0.2592
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Entamoeba histolytica hypothetical protein 0.1169 0.3715 1
Trichomonas vaginalis CMGC family protein kinase 0.0361 0.0766 0.2735
Loa Loa (eye worm) hypothetical protein 0.0251 0.0366 0.0366
Trypanosoma cruzi cdc2-related kinase 1 0.0361 0.0766 0.3101
Giardia lamblia Kinase, CK1 Casein kinase 0.0329 0.0653 0.2639
Entamoeba histolytica protein kinase, putative 0.0371 0.0805 0.2161
Loa Loa (eye worm) hypothetical protein 0.0174 0.0085 0.0085
Trypanosoma cruzi aurora B kinase, putative 0.0443 0.1066 0.4316
Brugia malayi Protein kinase domain containing protein 0.0256 0.0384 0.0384
Echinococcus multilocularis calcium dependent protein kinase 0.0209 0.0213 0.0356
Echinococcus granulosus tyrosine protein kinase shark 0.0699 0.2002 0.228
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0557 0.1984
Schistosoma mansoni tyrosine kinase 0.096 0.295 0.538
Trichomonas vaginalis STE family protein kinase 0.0193 0.0155 0.0547
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0303 0.0556 0.2047
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0234 0.0426
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0633
Loa Loa (eye worm) CAMK protein kinase 0.0198 0.0175 0.0175
Echinococcus multilocularis insulin receptor 0.1184 0.377 0.6303
Brugia malayi Protein kinase domain containing protein 0.0346 0.0714 0.0714
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0437 0.0796
Loa Loa (eye worm) hypothetical protein 0.0936 0.2863 0.2863
Schistosoma mansoni tyrosine kinase 0.0559 0.1489 0.2716
Trypanosoma brucei aurora B kinase 0.0443 0.1066 0.3807
Brugia malayi intracellular kinase 0.0391 0.0877 0.0877
Entamoeba histolytica PH domain containing protein kinase, putative 0.0502 0.1281 0.3443
Leishmania major casein kinase, putative 0.0329 0.0653 0.2639
Trypanosoma cruzi polo-like protein kinase, putative 0.0827 0.2465 1
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0565 0.103
Entamoeba histolytica protein kinase, putative 0.0213 0.0228 0.0608
Echinococcus granulosus protein tyrosine kinase 0.0913 0.2782 0.3168
Loa Loa (eye worm) TK/ALK protein kinase 0.0615 0.1695 0.1695
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0329 0.0653 0.2639
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0468 0.1157 0.4134
Brugia malayi Serine/threonine-protein kinase Pim-3 0.108 0.3389 0.3389
Echinococcus granulosus growth factor receptor bound protein 2 0.0229 0.0287 0.0327
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0371 0.0805 0.0805
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0808 0.2398 0.4009
Echinococcus multilocularis hypothetical protein 0.0273 0.0446 0.0746
Trichomonas vaginalis AGC family protein kinase 0.0575 0.1547 0.553
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.027 0.0437 0.0437
Entamoeba histolytica protein kinase domain containing protein 0.022 0.0254 0.0678
Schistosoma mansoni protein kinase 0.133 0.4301 0.7843
Schistosoma mansoni tyrosine kinase 0.096 0.295 0.538
Echinococcus multilocularis c src tyrosine kinase 0.0349 0.0723 0.1208
Entamoeba histolytica p21-activated kinase 0.0284 0.0489 0.131
Schistosoma mansoni serine/threonine protein kinase 0.0911 0.2772 0.5055
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0485 0.1219 0.1219
Loa Loa (eye worm) hypothetical protein 0.0253 0.0372 0.0372
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0253 0.0373 0.1371
Brugia malayi hypothetical protein 0.0253 0.0372 0.0372
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0443 0.1066 0.2863
Echinococcus multilocularis cyclin dependent kinase 1 0.0361 0.0766 0.1281
Echinococcus granulosus tyrosine protein kinase Fyn 0.0559 0.1489 0.1696
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1518 0.4988 0.4988
Echinococcus granulosus twitchin 0.0364 0.078 0.0888
Trypanosoma cruzi SNF1-related protein kinases, putative 0.027 0.0437 0.1762
Entamoeba histolytica PH domain containing protein kinase, putative 0.0328 0.0646 0.1733
Schistosoma mansoni serine/threonine protein kinase 0.077 0.2261 0.4123
Loa Loa (eye worm) CAMK/PIM protein kinase 0.108 0.3389 0.3389
Trypanosoma brucei SNF1-related protein kinases, putative 0.027 0.0437 0.1554
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0361 0.0766 0.0766
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0361 0.0766 0.0873
Schistosoma mansoni protein kinase 0.054 0.1422 0.2592
Trichomonas vaginalis CMGC family protein kinase 0.0391 0.0877 0.3131
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0903 0.2744 0.3126
Echinococcus multilocularis calcium activated potassium channel 0.0369 0.0798 0.1334
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0253 0.0373 0.1504
Echinococcus granulosus cyclin dependent kinase 1 0.0361 0.0766 0.0873
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0261 0.0402 0.0733
Trichomonas vaginalis AGC family protein kinase 0.0443 0.1066 0.3807
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1375 0.4465 0.4465
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0163 0.0047 0.0047
Schistosoma mansoni protein kinase 0.0588 0.1597 0.2911
Leishmania major protein kinase A catalytic subunit isoform 1 0.0303 0.0556 0.2246
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0303 0.0556 0.0929
Giardia lamblia Kinase, CMGC MAPK 0.0253 0.0373 0.1504
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0371 0.0805 0.3258
Giardia lamblia Kinase, AGC PKA 0.0303 0.0556 0.2246
Loa Loa (eye worm) hypothetical protein 0.0433 0.1029 0.1029
Schistosoma mansoni tyrosine kinase 0.096 0.295 0.538
Leishmania major protein kinase, putative 0.0255 0.0383 0.1546
Schistosoma mansoni tyrosine kinase 0.1083 0.3401 0.6202
Trichomonas vaginalis STE family protein kinase 0.026 0.0398 0.1418
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1516 0.4979 0.8323
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Brugia malayi Protein kinase domain containing protein 0.0615 0.1695 0.1695
Schistosoma mansoni growth factor receptor-bound protein 0.0225 0.0272 0.0496
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0318 0.0612 0.0697
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0246 0.0348 0.0348
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0261 0.0402 0.0402
Schistosoma mansoni tyrosine kinase 0.0699 0.2002 0.365
Trichomonas vaginalis CMGC family protein kinase 0.0391 0.0877 0.3131
Echinococcus multilocularis mitogen activated protein kinase 11 0.0485 0.1219 0.2037
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus granulosus tyrosine protein kinase Lyn 0.0655 0.1841 0.2097
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.108 0.3389 0.7871
Trichomonas vaginalis AGC family protein kinase 0.0917 0.2795 1
Trypanosoma brucei Casein kinase II 0.0303 0.0557 0.1984
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0478 0.1195 0.4271
Leishmania major protein kinase, putative 0.0305 0.0565 0.2283
Echinococcus granulosus serine threonine protein kinase nrc 0.0477 0.1191 0.1356
Trichomonas vaginalis STE family protein kinase 0.0255 0.0383 0.1363
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0391 0.0877 0.355
Schistosoma mansoni tyrosine kinase 0.1654 0.5484 1
Echinococcus granulosus c src tyrosine kinase 0.0349 0.0723 0.0823
Loa Loa (eye worm) TK protein kinase 0.0334 0.0669 0.0669
Giardia lamblia Kinase, STE STE20 0.0255 0.0383 0.1546
Giardia lamblia Kinase, CMGC CK2 0.0303 0.0557 0.225
Toxoplasma gondii AGC kinase 0.0303 0.0556 0.2047
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0665 0.1875 0.1875
Echinococcus multilocularis tyrosine protein kinase 0.0861 0.2592 0.4333
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0305 0.0565 0.0643
Echinococcus granulosus insulin receptor 0.1184 0.377 0.4295
Schistosoma mansoni serine/threonine protein kinase 0.0512 0.1317 0.2402
Loa Loa (eye worm) TK/EPH protein kinase 0.0375 0.0818 0.0818
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.133 0.4301 0.4899
Echinococcus multilocularis raf serine:threonine protein kinase 0.0252 0.0372 0.0621
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0618 0.1707 0.1707
Leishmania major casein kinase II, putative 0.0303 0.0557 0.225
Giardia lamblia Kinase, CMGC GSK 0.0391 0.0877 0.355
Loa Loa (eye worm) hypothetical protein 0.0197 0.017 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0556 0.1014
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0253 0.0373 0.0373
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.108 0.3389 0.386
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.05 0.1274 0.213
Echinococcus multilocularis NCK adaptor protein 0.0229 0.0287 0.048
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0556 0.1014
Echinococcus granulosus protein kinase c epsilon type 0.0644 0.1801 0.2051
Trypanosoma cruzi polo-like protein kinase, putative 0.0827 0.2465 1
Trichomonas vaginalis AGC family protein kinase 0.0599 0.1637 0.5854
Trypanosoma brucei cdc2-related kinase 1 0.0361 0.0766 0.2735
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0047 0.0085
Plasmodium falciparum serine/threonine protein kinase, putative 0.0443 0.1066 0.8948
Brugia malayi protein-tyrosine kinase 0.0466 0.115 0.115
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0163 0.0047 0.0158
Echinococcus granulosus aurora kinase A 0.0443 0.1066 0.1214
Trichomonas vaginalis CAMK family protein kinase 0.0827 0.2465 0.882
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0619 0.1708 0.1946
Echinococcus multilocularis mitogen activated protein kinase 3 0.0253 0.0373 0.0623
Onchocerca volvulus 0.0197 0.017 0.003
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Entamoeba histolytica casein kinase, putative 0.0303 0.0557 0.1492
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0251 0.0366 0.0366
Echinococcus multilocularis tyrosine protein kinase Abl 0.0429 0.1017 0.17
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0619 0.1708 0.1946
Entamoeba histolytica serine/threonine protein kinase, putative 0.0827 0.2465 0.6634
Onchocerca volvulus 0.0233 0.0301 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0441 0.1058 0.1769
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1208 0.3856 0.4392
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0366 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0348 0.1236
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0305 0.0565 0.4733
Schistosoma mansoni tyrosine kinase 0.022 0.0254 0.0464
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0246 0.0348 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0348 0.0634
Schistosoma mansoni hypothetical protein 0.0318 0.0612 0.1115
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0485 0.1219 0.4938
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.026 0.0398 0.0454
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0303 0.0556 0.1981
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0305 0.0565 0.4733
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0255 0.0383 0.1546
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0485 0.1219 0.4938
Loa Loa (eye worm) hypothetical protein 0.0346 0.0714 0.0714
Entamoeba histolytica protein kinase, putative 0.0512 0.1317 0.3542
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0369 0.0796 0.3221
Giardia lamblia Kinase, CAMK CAMKL 0.027 0.0437 0.1762
Brugia malayi serine/threonine kinase 12 0.0443 0.1066 0.1066
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0305 0.0565 0.0565
Brugia malayi Furin-like cysteine rich region family protein 0.1654 0.5484 0.5484
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0318 0.0612 0.1022
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0477 0.1191 0.1356
Trichomonas vaginalis CMGC family protein kinase 0.0361 0.0766 0.2735
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0437 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0373 0.068
Loa Loa (eye worm) AUR protein kinase 0.0443 0.1066 0.1066
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.077 0.2261 0.2575
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.022 0.0254 0.1022
Loa Loa (eye worm) hypothetical protein 0.1275 0.41 0.41
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1083 0.3401 0.3874
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0033 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0123 0.0431
Toxoplasma gondii casein kinase I 0.0329 0.0653 0.2405
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0443 0.1066 0.8948
Onchocerca volvulus 0.0391 0.0877 0.1753
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.077 0.2261 0.2261
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0459 0.1126 0.1126
Loa Loa (eye worm) casein kinase 0.0555 0.1474 0.1474
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0709 0.1292
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0391 0.0877 0.1599
Giardia lamblia Kinase, CMGC GSK 0.0391 0.0877 0.355
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0796 0.2841
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0437 0.0796
Echinococcus granulosus tyrosine kinase 0.0466 0.115 0.131
Brugia malayi protein unc-22 0.0198 0.0175 0.0175
Giardia lamblia Kinase, CDC7 0.0214 0.0234 0.0939
Loa Loa (eye worm) TK/FER protein kinase 0.0256 0.0384 0.0384
Loa Loa (eye worm) TK protein kinase 0.0861 0.2592 0.2592
Giardia lamblia Kinase, CAMK CAMKL 0.027 0.0437 0.1762
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0184 0.0123 0.0431
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0512 0.1317 0.2202
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0305 0.0565 0.2081
Trichomonas vaginalis CAMK family protein kinase 0.027 0.0437 0.1554
Echinococcus granulosus casein kinase I gamma 0.0651 0.1826 0.2079
Echinococcus granulosus dual specificity 0.0369 0.0796 0.0907

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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