Detailed information for compound 705063

Basic information

Technical information
  • TDR Targets ID: 705063
  • Name: N-(2-furan-2-yl-2-thiophen-2-ylsulfonylethyl) -2,5-dimethoxybenzenesulfonamide
  • MW: 457.541 | Formula: C18H19NO7S3
  • H donors: 1 H acceptors: 4 LogP: 2.41 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c(c1)S(=O)(=O)NCC(S(=O)(=O)c1cccs1)c1ccco1)OC
  • InChi: 1S/C18H19NO7S3/c1-24-13-7-8-14(25-2)16(11-13)29(22,23)19-12-17(15-5-3-9-26-15)28(20,21)18-6-4-10-27-18/h3-11,17,19H,12H2,1-2H3
  • InChiKey: YKXVHKAELVODDM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-(2-furyl)-2-(2-thienylsulfonyl)ethyl]-2,5-dimethoxy-benzenesulfonamide
  • N-[2-(2-furyl)-2-(2-thienylsulfonyl)ethyl]-2,5-dimethoxybenzenesulfonamide
  • N-(2-furan-2-yl-2-thiophen-2-ylsulfonyl-ethyl)-2,5-dimethoxy-benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0028 0.0027
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0027 0.008
Onchocerca volvulus 0.0177 0.2223 0.2832
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0137
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0442 0.5776 0.7357
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Loa Loa (eye worm) hypothetical protein 0.0043 0.044 0.0561
Onchocerca volvulus 0.0013 0.0027 0.0035
Plasmodium vivax protein tyrosine phosphatase, putative 0.0023 0.017 0.0732
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0029 0.0247 0.0247
Brugia malayi jmjC domain containing protein 0.0105 0.1263 0.1609
Loa Loa (eye worm) heterochromatin protein 1 0.0077 0.0884 0.1126
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0379 0.0482
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Onchocerca volvulus 0.0012 0.0027 0.0034
Echinococcus multilocularis L aminoadipate semialdehyde 0.0177 0.2223 0.2223
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0813 0.0813
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0525 0.1757
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0028 0.0028
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0092 0.0092
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0092 0.0092
Onchocerca volvulus 0.0012 0.0027 0.0034
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0028 0.0035
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0044 0.0442 0.0563
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.0027 0.0034
Brugia malayi chromobox protein homolog 3 0.0043 0.0434 0.0553
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0028 0.0118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.009 0.0275
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0277 0.3562 0.3562
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0185 0.2329 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0026 0.0203 0.0203
Onchocerca volvulus 0.0013 0.0028 0.0035
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0011 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0157 0.0157
Brugia malayi hypothetical protein 0.0011 0.0008 0.001
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0157 0.0157
Brugia malayi nuclear receptor NHR-88 0.0022 0.0157 0.02
Brugia malayi serine/threonine-protein kinase plk-2 0.0104 0.1248 0.159
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0044 0.0442 0.3403
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0013 0.0027 0.0083
Mycobacterium ulcerans hypothetical protein 0.0024 0.0186 0.0765
Loa Loa (eye worm) hypothetical protein 0.0106 0.1281 0.1632
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1586 0.6797
Brugia malayi endonuclease G, mitochondrial precursor 0.0166 0.2084 0.2654
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0027 0.0034
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) retinol dehydrogenase 12 0.0013 0.0027 0.0035
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0592 0.0755
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0813 0.3467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus multilocularis peregrin 0.0032 0.0288 0.0288
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0442 0.0563
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0277 0.3562 0.4537
Schistosoma mansoni nuclear hormone receptor 0.001 0.0000087243 0.0000087243
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus multilocularis RUN 0.0022 0.015 0.015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0532 0.0532
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0044 0.0442 0.0442
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0027 0.0114
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0157 0.0157
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0103 0.033
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0884 0.1305
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0027 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0028 0.0118
Loa Loa (eye worm) dehydrogenase 0.0012 0.0027 0.0034
Trypanosoma cruzi endonuclease G, putative 0.0166 0.2084 0.6951
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0044 0.0442 0.0563
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0166 0.2084 0.6951
Mycobacterium tuberculosis Conserved protein 0.0027 0.022 0.084
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0028 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0288 0.0367
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0027 0.0026
Mycobacterium leprae hypothetical protein 0.0044 0.0442 0.1805
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0008
Echinococcus multilocularis muscleblind protein 1 0.031 0.4009 0.4009
Brugia malayi MH2 domain containing protein 0.0117 0.1422 0.1811
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0044 0.0442 0.3403
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.1586 0.1586
Schistosoma mansoni hypothetical protein 0.0017 0.0092 0.0092
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0185 0.2329 1
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1586 0.6797
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0185 0.2329 1
Schistosoma mansoni rab6-interacting 0.0022 0.015 0.015
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0403 0.3085
Onchocerca volvulus 0.0106 0.1281 0.1632
Schistosoma mansoni kinase 0.0053 0.0565 0.0565
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0177 0.2223 0.2223
Leishmania major tyrosine specific protein phosphatase, putative 0.002 0.0125 0.0334
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0044 0.0442 0.0563
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Loa Loa (eye worm) hypothetical protein 0.0034 0.031 0.0395
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.009 0.0275
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0157 0.0157
Brugia malayi Pre-SET motif family protein 0.0442 0.5776 0.7357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0157 0.02
Echinococcus multilocularis GPCR, family 2 0.0017 0.0092 0.0092
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0027 0.0026
Brugia malayi Muscleblind-like protein 0.031 0.4009 0.5107
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0975 0.0975
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0166 0.2084 0.6951
Trypanosoma brucei phosphatase of regenerating liver-type phosphatase, putative 0.0023 0.017 0.0571
Loa Loa (eye worm) hypothetical protein 0.0044 0.0442 0.0563
Echinococcus multilocularis Mastin 0.0011 0.0008 0.0008
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0027 0.008
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0092 0.0117
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0027 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0708 0.0708
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0813 0.0813
Echinococcus granulosus chromobox protein 1 0.0077 0.0884 0.0884
Onchocerca volvulus 0.0012 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0013 0.0027 0.0027
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0379 0.0379
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0379 0.0379
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0671 0.0671
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0157 0.0157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0023 0.0168 0.0168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0157 0.02
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0103 0.0131
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.1792 0.1792
Echinococcus granulosus Chromo domain 0.0013 0.0028 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.1586 0.6772
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0013 0.0027 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0027 0.0035
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0013 0.0027 0.0003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0157 0.02
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0027 0.008
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Brugia malayi steroid hormone receptor 0.0022 0.0157 0.02
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0532 0.0678
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0003
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.022 0.0295
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0044 0.0442 0.0442
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.1586 0.5269
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Echinococcus multilocularis Chromo domain 0.0013 0.0028 0.0027
Echinococcus granulosus L aminoadipate semialdehyde 0.0177 0.2223 0.2223
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0157 0.0157
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0023 0.017 0.1178
Onchocerca volvulus 0.0011 0.0008 0.001
Echinococcus granulosus transmembrane protease serine 3 0.0011 0.0008 0.0008
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0813 0.2657
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0525 0.2226
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0013 0.0027 0.0117
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.001
Onchocerca volvulus 0.0022 0.015 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0234 0.2986 1
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0028 0.0027
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0185 0.2329 1
Echinococcus granulosus Chromobox protein 3 0.0013 0.0028 0.0027
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0027 0.0089
Brugia malayi Trypsin family protein 0.0106 0.1281 0.1632
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0477 0.0608
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0403 0.0403
Schistosoma mansoni hypothetical protein 0.0044 0.0442 0.0442
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0000087243 0.0000087243
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0027 0.0114
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0166 0.2084 0.6951
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Onchocerca volvulus 0.0012 0.0027 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0434 0.062
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0186 0.0236
Giardia lamblia Kinase, PLK 0.0104 0.1248 1
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1586 0.1586
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0044 0.0442 0.0563
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0288 0.1238
Loa Loa (eye worm) hypothetical protein 0.0101 0.1212 0.1544
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0157 0.02
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0044 0.0442 0.3403
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0027 0.0026
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0186 0.0765
Brugia malayi hypothetical protein 0.0022 0.015 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0266 0.0365
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0027 0.008
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0277 0.3562 0.3562
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0525 0.2161
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0002
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0000087243 0.0000087243
Echinococcus multilocularis sortilin receptor 0.0016 0.0073 0.0073
Brugia malayi CHE-14 protein 0.0043 0.044 0.0561
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0477 0.0687
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0012 0.0027 0.0089
Leishmania major hypothetical protein, conserved 0.0234 0.2986 1
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Loa Loa (eye worm) hypothetical protein 0.0018 0.0103 0.0131
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0525 0.2252
Onchocerca volvulus 0.0034 0.031 0.0395
Schistosoma mansoni hypothetical protein 0.0017 0.0092 0.0092
Trichomonas vaginalis hypothetical protein 0.0185 0.2329 0.3507
Entamoeba histolytica hypothetical protein 0.0013 0.0028 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0103 0.041
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0157 0.0157
Echinococcus granulosus Endonuclease G 0.0166 0.2084 0.2084
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0186 0.0765
Onchocerca volvulus 0.002 0.0125 0.0159
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0194 0.08
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0027 0.0114
Loa Loa (eye worm) hypothetical protein 0.0055 0.0594 0.0757
Echinococcus granulosus RUN 0.0022 0.015 0.015
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0157 0.0157
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0104 0.1248 0.159
Onchocerca volvulus 0.0597 0.785 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0024 0.0181 0.0231
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0092 0.0092
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0194 0.08
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0168 0.0168
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0092 0.0117
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.022 0.084
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.044 0.044
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0027 0.0089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0092 0.0117
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0103 0.0131
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0092 0.0092
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0525 0.5
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0011 0.0008 0.0008
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0028 0.0028
Onchocerca volvulus 0.0011 0.0008 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Echinococcus granulosus hypothetical protein 0.0012 0.0027 0.0026
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0288 0.0288
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0157 0.0157
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0379 0.0378
Echinococcus multilocularis protein dispatched 1 0.0049 0.0522 0.0522
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0477 0.0687
Entamoeba histolytica hypothetical protein 0.0013 0.0028 0.0008
Loa Loa (eye worm) doublecortin family protein 0.0022 0.015 0.0191
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0157 0.0157
Trypanosoma cruzi endonuclease G, putative 0.0166 0.2084 0.6951
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Leishmania major protein tyrosine phosphatase-likie protein 0.0023 0.017 0.0486
Brugia malayi Bromodomain containing protein 0.0032 0.0288 0.0367
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.022 0.022
Schistosoma mansoni chromobox protein 0.0077 0.0884 0.0884
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Echinococcus granulosus ectonucleotide 0.0233 0.2979 0.2979
Echinococcus multilocularis muscleblind protein 0.031 0.4009 0.4009
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0024 0.0181 0.0231
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1586 0.1586
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0104 0.1248 0.1248
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0027 0.0026
Brugia malayi hypothetical protein 0.0012 0.0027 0.0034
Schistosoma mansoni nuclear receptor 0.001 0.0000087243 0.0000087243
Brugia malayi hypothetical protein 0.0022 0.015 0.0191
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0125 0.0125
Schistosoma mansoni polycystin 1-related 0.0022 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Schistosoma mansoni protein tyrosine phosphatase prl 0.0023 0.017 0.017
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0525 0.2252
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0012 0.0027 0.0089
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0028 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0157 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0532 0.0532
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0361 0.046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0027 0.0026
Trypanosoma brucei polo-like protein kinase 0.0104 0.1248 0.418
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1586 0.6797
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0027 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0044 0.0442 0.0442
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0157 0.02
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Echinococcus multilocularis glycoprotein Antigen 5 0.0011 0.0008 0.0008
Brugia malayi Trypsin family protein 0.0011 0.0008 0.001
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0027 0.0026
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0028 0.0118
Echinococcus granulosus chromobox protein 2 0.0013 0.0028 0.0027
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0023 0.0168 0.0214
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0745 0.0948
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0186 0.1302
Onchocerca volvulus Alhambra homolog 0.0032 0.0288 0.0367
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Onchocerca volvulus 0.0022 0.015 0.0191
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0403 0.1351
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0186 0.069
Plasmodium vivax SET domain protein, putative 0.0063 0.0708 0.3042
Onchocerca volvulus 0.0012 0.0027 0.0034
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.017 0.0486
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0157 0.02
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0027 0.008
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0277 0.3562 0.4537
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0027 0.0002
Plasmodium falciparum enoyl-acyl carrier reductase 0.0185 0.2329 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0403 0.0514
Trypanosoma brucei hypothetical protein, conserved 0.0234 0.2986 1
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0028 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0532 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Loa Loa (eye worm) hypothetical protein 0.0277 0.3562 0.4537
Mycobacterium ulcerans hypothetical protein 0.0027 0.022 0.0913
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0157 0.02
Echinococcus granulosus chromobox protein 1 0.0077 0.0884 0.0884
Schistosoma mansoni hypothetical protein 0.0042 0.0419 0.0419
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0191
Mycobacterium ulcerans oxidoreductase 0.0012 0.0027 0.008
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0027 0.0026
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0027 0.0034
Mycobacterium ulcerans hypothetical protein 0.0027 0.022 0.0913
Schistosoma mansoni hypothetical protein 0.0597 0.785 0.785
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0013 0.0027 0.0083
Loa Loa (eye worm) hypothetical protein 0.0277 0.3562 0.4537
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0157 0.02
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0114
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0044 0.0442 0.0442
Schistosoma mansoni carbonyl reductase 0.0012 0.0027 0.0027
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.031 0.4009 0.5107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0442 0.0563
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.1212 0.1212
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0157 0.02
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0708 0.0708
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0592 0.0755
Loa Loa (eye worm) helicase 0.0013 0.0028 0.0035
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0403 0.0403
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0027 0.0034
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0157 0.0157
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0029 0.0247 0.0247
Brugia malayi Protein cec-1. 0.0013 0.0028 0.0035
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0157 0.02
Schistosoma mansoni hypothetical protein 0.0042 0.0419 0.0419
Schistosoma mansoni carbonyl reductase 0.0012 0.0027 0.0027
Echinococcus granulosus enteropeptidase 0.0011 0.0008 0.0008
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.1586 0.6808
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.1586 0.1586
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0114
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.022 0.0654
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0115 0.0147
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.022 0.0654
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0177 0.2223 0.2832
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0157 0.0157
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0525 0.2163
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0157 0.02
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0456 0.0456
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Brugia malayi Heterochromatin protein 1 0.0077 0.0884 0.1126
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0022
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.015 0.0643
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0008
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0044 0.0442 0.1898
Onchocerca volvulus 0.0011 0.0008 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0017 0.0022
Schistosoma mansoni hypothetical protein 0.0044 0.0442 0.0442
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0157 0.02
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0027 0.0114
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.1212 0.1212
Onchocerca volvulus 0.0277 0.3562 0.4537
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Plasmodium falciparum phd finger protein, putative 0.0032 0.0288 0.1238
Loa Loa (eye worm) hypothetical protein 0.0177 0.2223 0.2832
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0022
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0157 0.02
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0157 0.02
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1422 0.1811
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0157 0.02
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0027 0.008
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Onchocerca volvulus 0.0012 0.0027 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Trypanosoma brucei endonuclease G, putative 0.0166 0.2084 0.6978
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0186 0.0537
Leishmania major protein tyrosine phosphatase-like protein 0.0023 0.017 0.0486
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.044 0.0561
Loa Loa (eye worm) hypothetical protein 0.0018 0.0103 0.0131
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.017 0.0486
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0157 0.0157
Schistosoma mansoni zinc finger protein 0.001 0.0000087243 0.0000087243
Brugia malayi Doublecortin family protein 0.0022 0.015 0.0191
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0031 0.004
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0012 0.0027 0.0089
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0028 0.0118
Schistosoma mansoni carbonyl reductase 0.0012 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0044 0.0442 0.0442
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0103 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0185 0.2329 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0532 0.0532
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0013 0.0027 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0186 0.0236
Brugia malayi hypothetical protein 0.0044 0.0442 0.0563
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0044 0.0442 0.1481
Brugia malayi oxidoreductase 0.0012 0.0027 0.0034
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0525 0.2252
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0055 0.0592 0.0755
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0194 0.08
Schistosoma mansoni chromobox protein 0.0013 0.0028 0.0028
Onchocerca volvulus 0.0012 0.0027 0.0034
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0157 0.02
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0027 0.0034
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0028 0.0027
Trichomonas vaginalis set domain proteins, putative 0.0503 0.6593 1
Echinococcus multilocularis transmembrane protease serine 3 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0708 0.0903
Schistosoma mansoni hypothetical protein 0.0013 0.0028 0.0028
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0025 0.0194 0.08
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0266 0.0365
Echinococcus multilocularis chromobox protein 1 0.0077 0.0884 0.0884
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0044 0.0442 0.0563
Onchocerca volvulus 0.0503 0.6593 0.8398
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0013 0.0027 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0013 0.0027 0.0117
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0025 0.0194 0.0832
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.1248 1
Echinococcus granulosus oxidoreductase 0.0012 0.0027 0.0026
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0288 0.0288
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0168 0.0168
Echinococcus multilocularis Endonuclease G 0.0166 0.2084 0.2084
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0813 0.1036
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0002
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0028 0.0118
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0186 0.069
Brugia malayi Thrombospondin type 1 domain containing protein 0.0597 0.785 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0288 0.1238
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0013 0.0027 0.0117
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.022 0.0913
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.1792 0.1792
Onchocerca volvulus 0.0277 0.3562 0.4537
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0813 0.3414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) oxidoreductase 0.0013 0.0027 0.0035
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0157 0.02
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0027 0.0089
Brugia malayi M-phase phosphoprotein, mpp8 0.0013 0.0028 0.0035
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Leishmania major oxidoreductase-like protein 0.0025 0.0194 0.0565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0157 0.02
Schistosoma mansoni patched 1 0.0043 0.044 0.044
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0027 0.0026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0022
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0185 0.2329 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0157 0.02
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.017 0.0486
Loa Loa (eye worm) hypothetical protein 0.0018 0.0103 0.0131
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.017 0.0486
Brugia malayi AEL166Cp 0.0044 0.0442 0.0563
Schistosoma mansoni hypothetical protein 0.0042 0.0419 0.0419
Leishmania major endonuclease G, putative 0.0166 0.2084 0.6951
Echinococcus granulosus hypothetical protein 0.0012 0.0027 0.0026
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0028 0.0028
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.1248 0.4127
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0379 0.0378
Echinococcus granulosus protein tyrosine phosphatase PRL 0.0023 0.017 0.017
Echinococcus granulosus peregrin 0.0032 0.0288 0.0288
Schistosoma mansoni hypothetical protein 0.0017 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0044 0.0442 0.0442
Schistosoma mansoni lipoxygenase 0.0022 0.015 0.015
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0011 0.0008 0.0008
Echinococcus multilocularis transferase 0.0044 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Schistosoma mansoni protein tyrosine phosphatase prl 0.0023 0.017 0.017
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0104 0.1248 0.1248
Entamoeba histolytica hypothetical protein 0.005 0.0525 0.4078
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0027 0.0027
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0027 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0592 0.0755
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0011 0.0008 0.0008
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0027 0.0083
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Loa Loa (eye worm) hypothetical protein 0.0037 0.0361 0.046
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.015 0.015
Mycobacterium leprae conserved hypothetical protein 0.005 0.0525 0.2163
Schistosoma mansoni hypothetical protein 0.0042 0.0419 0.0419
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0027 0.0026
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0027 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0186 0.0537
Brugia malayi Trypsin family protein 0.0011 0.0008 0.001
Brugia malayi hypothetical protein 0.0044 0.0442 0.0563
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0027 0.0026
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.0027 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0157 0.02
Brugia malayi nuclear receptor RXR 0.0012 0.0017 0.0022
Onchocerca volvulus 0.0012 0.0027 0.0034
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.009 0.0275
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0403 0.0403
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0708 0.0708
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0027 0.0083
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0125 0.0125
Brugia malayi hypothetical protein 0.0012 0.0027 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0017 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0000087243 0.0000087243
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Brugia malayi PHD-finger family protein 0.0032 0.0288 0.0367
Echinococcus multilocularis protein patched 0.0043 0.044 0.044
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0013 0.0027 0.0003
Brugia malayi ecdysteroid receptor 0.0022 0.0157 0.02
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0125 0.0125
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.044 0.063
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0813 0.0813
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0186 0.1302
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0027 0.0089
Onchocerca volvulus 0.0076 0.0876 0.1116
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0403 0.1273
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0028 0.0027
Onchocerca volvulus 0.0011 0.0008 0.001
Mycobacterium ulcerans hypothetical protein 0.0044 0.0442 0.187
Brugia malayi Trypsin family protein 0.0011 0.0008 0.001
Echinococcus multilocularis microtubule associated protein 2 0.0758 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.009 0.0275
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0013 0.0027 0.0027
Giardia lamblia PHD finger protein 15 0.0032 0.0288 0.2144
Schistosoma mansoni microtubule-associated protein tau 0.0758 1 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0194 0.0726
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0035
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0434 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0157 0.02
Entamoeba histolytica hypothetical protein 0.0013 0.0028 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0547 0.0793
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.0027 0.008
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0017 0.0017
Loa Loa (eye worm) trypsin family protein 0.0011 0.0008 0.001
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.002 0.0125 0.016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0186 0.0236
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0027 0.0026
Echinococcus multilocularis enteropeptidase 0.0011 0.0008 0.0008
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0027 0.0026
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0442 0.0563
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0813 0.3467
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0027 0.0002
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0277 0.3562 0.3562
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0027 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Schistosoma mansoni dihydropteridine reductase 0.0013 0.0027 0.0027
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0027 0.0026
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.0027 0.0114
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0028 0.0002
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0103 0.0443
Echinococcus granulosus expressed conserved protein 0.0095 0.113 0.113
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0234 0.2986 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0403 0.3085
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0525 0.2163
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0027 0.0027
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.0027 0.008
Trypanosoma brucei endonuclease G, putative 0.0166 0.2084 0.6978
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.1248 0.1248
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0013 0.0027 0.0117
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.1263 0.1263
Echinococcus multilocularis ectonucleotide 0.0233 0.2979 0.2979
Onchocerca volvulus 0.0012 0.0027 0.0034
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0166 0.2084 0.8945
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Schistosoma mansoni rab6-interacting 0.0022 0.015 0.015
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0027 0.0026
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.1212 0.1544
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0157 0.02
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0027 0.0083
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0044 0.0442 0.0442
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0403 0.0403
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0013 0.0027 0.0083
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0186 0.069
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0017 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0403 0.0403
Onchocerca volvulus 0.0024 0.0186 0.0236
Echinococcus granulosus GPCR family 2 0.0017 0.0092 0.0092
Schistosoma mansoni endonuclease related 0.0166 0.2084 0.2084
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0288 0.0367
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0403 0.1273
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.0027 0.0034
Echinococcus multilocularis protein tyrosine phosphatase PRL 0.0023 0.017 0.017
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0157 0.0157
Echinococcus granulosus transferase 0.0044 0.0442 0.0442
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0027 0.0026
Echinococcus multilocularis expressed conserved protein 0.0095 0.113 0.113
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0884 0.1305
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0157 0.0157
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0277 0.3562 0.3562
Loa Loa (eye worm) hypothetical protein 0.031 0.4009 0.5107
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0092 0.0117
Onchocerca volvulus Serine\/threonine kinase homolog 0.0104 0.1248 0.159
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.015 0.0643
Trypanosoma brucei pteridine reductase 1 0.0013 0.0027 0.0091
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Brugia malayi Trypsin-like protease protein 5 0.0011 0.0008 0.001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0106 0.1281 0.1281
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0671 0.0671
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0044 0.0442 0.0442
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0027 0.0003
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0044 0.0442 0.0442
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0403 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0022
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0708 0.3042
Schistosoma mansoni loxhd1 0.0022 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.001
Trypanosoma brucei oxidoreductase-like protein 0.0025 0.0194 0.0649
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0114
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0186 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0028 0.0035
Onchocerca volvulus 0.0011 0.0008 0.001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0186 0.0236
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0028 0.0118
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0008
Schistosoma mansoni hypothetical protein 0.0017 0.0092 0.0092
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0103 0.0443
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0028 0.0035
Mycobacterium ulcerans dehydrogenase 0.0012 0.0027 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0157 0.02
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0157 0.02
Trichomonas vaginalis hypothetical protein 0.0013 0.0028 0.0002
Onchocerca volvulus 0.0012 0.0027 0.0034
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.0027 0.008
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0456 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0434 0.062
Plasmodium falciparum protein tyrosine phosphatase 0.0023 0.017 0.0732
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0157 0.0157
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0027 0.0026
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0027 0.0034
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0403 0.1273
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0403 0.0403
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0029 0.0247 0.0247
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.044 0.044
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0011 0.0008 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0157 0.02
Schistosoma mansoni hypothetical protein 0.0032 0.0288 0.0288
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0403 0.0514
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0185 0.2329 1
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0027 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Plasmodium falciparum heterochromatin protein 1 0.0013 0.0028 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans oxidoreductase 0.0013 0.0027 0.0083
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0027 0.0027
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.0027 0.0114
Echinococcus multilocularis chromobox protein 1 0.0077 0.0884 0.0884
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0012 0.0027 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0157 0.02
Schistosoma mansoni chromobox protein 0.0077 0.0884 0.0884
Leishmania major ethanolamine phosphotransferase, putative 0.0044 0.0442 0.1405
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0114
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.015 0.015
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.022 0.0913
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0157 0.0157
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0191
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.017 0.0486
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0012 0.0027 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0129 0.0156
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0525 0.2252
Brugia malayi SET domain containing protein 0.0015 0.0059 0.0075
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.015 0.015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0403 0.0574
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0525 0.1683
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0053 0.0571 0.0727
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.022 0.022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0677 0.0677
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0186 0.0765
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0013 0.0027 0.0091
Schistosoma mansoni nuclear hormone receptor 0.001 0.0000087243 0.0000087243
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.015 0.015
Loa Loa (eye worm) dehydrogenase 0.0012 0.0027 0.0034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0186 0.0765
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0186 0.0765
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Trypanosoma brucei endonuclease G, putative 0.0166 0.2084 0.6978
Echinococcus multilocularis oxidoreductase 0.0012 0.0027 0.0026
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.017 0.0486
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.0876 0.0876
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0028 0.0118
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.017 0.0486
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.022 0.0654
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0186 0.069
Schistosoma mansoni nuclear receptor 0.001 0.0000087243 0.0000087243
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0027 0.0026
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0044 0.0442 0.0442
Echinococcus granulosus muscleblind protein 0.031 0.4009 0.4009
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1422 0.1811
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0157 0.0157
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.0008 0.0008
Onchocerca volvulus 0.0095 0.1133 0.1443
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0403 0.0574
Loa Loa (eye worm) hypothetical protein 0.0043 0.0434 0.0553
Brugia malayi CHD4 protein 0.0013 0.0028 0.0035
Brugia malayi hypothetical protein 0.0012 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Mycobacterium ulcerans oxidoreductase 0.0012 0.0027 0.008
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0233 0.2979 0.2979
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0104 0.1248 0.4127
Loa Loa (eye worm) hypothetical protein 0.0233 0.2979 0.3795
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0106 0.1281 0.1281
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0288 0.1238
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.1248 0.186
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0027 0.0026
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0013 0.0027 0.0003
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.0157 0.02
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0597 0.785 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0027 0.008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0157 0.0157
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Brugia malayi hypothetical protein 0.0013 0.0028 0.0035
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0044 0.0442 0.0563
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0813 0.1035
Brugia malayi jmjC domain containing protein 0.0039 0.0379 0.0482
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0532 0.0678
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Schistosoma mansoni chromobox protein 0.0013 0.0028 0.0028
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0027 0.0026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0027 0.008
Brugia malayi hypothetical protein 0.0012 0.0017 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0031 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0186 0.0236
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0157 0.0157
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0013 0.0027 0.0003
Onchocerca volvulus 0.0012 0.0027 0.0034
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.0008
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0013 0.0027 0.0002
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0186 0.1302
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Schistosoma mansoni lipoxygenase 0.0061 0.0671 0.0671
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0027 0.0027
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0157 0.0157
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0027 0.0114
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.1248 0.4127
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0288 0.0288
Echinococcus granulosus glycoprotein Antigen 5 0.0011 0.0008 0.0008
Brugia malayi nuclear hormone receptor 0.0022 0.0157 0.02
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.002 0.0125 0.0334
Brugia malayi Pre-SET motif family protein 0.0063 0.0708 0.0903
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.1212 0.9704
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0028 0.0118
Leishmania major pteridine reductase 1 0.0025 0.0194 0.0565
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0106 0.1281 0.1632
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0103 0.0333
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0233 0.2979 0.2979
Onchocerca volvulus 0.002 0.0122 0.0155
Echinococcus multilocularis chromobox protein 2 0.0013 0.0028 0.0027
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0027 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0532 0.0532
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0027 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0157 0.02
Schistosoma mansoni coup transcription factor 0.0022 0.0157 0.0157
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Toxoplasma gondii hypothetical protein 0.002 0.0129 0.0553
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0027 0.0026
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0029 0.0247 0.0247
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0157 0.0157
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0186 0.0765
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0028 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0023 0.0168 0.0168
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.1263 0.1263
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0028 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Onchocerca volvulus 0.0025 0.0194 0.0247
Echinococcus granulosus Protein patched homolog 1 0.0043 0.044 0.044
Schistosoma mansoni hypothetical protein 0.0037 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0035
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0186 0.0765
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0013 0.0027 0.0002
Onchocerca volvulus 0.0022 0.0157 0.02
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0029 0.0247 0.0247
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0027 0.0003
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0013 0.0027 0.0003
Trypanosoma cruzi protein tyrosine phosphatase PRL 0.0023 0.017 0.0486
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.015 0.015
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.002 0.0125 0.0334
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0017 0.0022
Loa Loa (eye worm) oxidoreductase 0.0012 0.0027 0.0034
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0044 0.0442 0.0563
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0547 0.0793
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0027 0.0114
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0027 0.0114
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0027 0.0089
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0027 0.008
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.0027 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0027 0.0034
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0186 0.0236
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0017 0.0022
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0025 0.0194 0.0565
Echinococcus granulosus Mastin 0.0011 0.0008 0.0008
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0013 0.0027 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0403 0.0403
Onchocerca volvulus 0.0013 0.0028 0.0035
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.015 0.015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0027 0.0083
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0708 0.0708
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0027 0.0035
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0525 0.2226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0532 0.0532
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0028 0.0028
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.022 0.0913
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0027 0.0083
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0277 0.3562 0.3561

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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