Detailed information for compound 78725

Basic information

Technical information
  • TDR Targets ID: 78725
  • Name: 2-(5-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl) -N-hydroxyacetamide
  • MW: 239.203 | Formula: C10H10FN3O3
  • H donors: 3 H acceptors: 3 LogP: -0.36 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)CN1Cc2c(F)cccc2NC1=O
  • InChi: 1S/C10H10FN3O3/c11-7-2-1-3-8-6(7)4-14(10(16)12-8)5-9(15)13-17/h1-3,17H,4-5H2,(H,12,16)(H,13,15)
  • InChiKey: KTBMCENDCYXNHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(5-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)ethanehydroxamic acid
  • 2-(5-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)-N-hydroxy-ethanamide
  • 2-(5-fluoro-2-keto-1,4-dihydroquinazolin-3-yl)ethanehydroxamic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli peptide deformylase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum Peptide deformylase, related Get druggable targets OG5_128237 All targets in OG5_128237
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) Get druggable targets OG5_128237 All targets in OG5_128237
Plasmodium knowlesi peptide deformylase, putative Get druggable targets OG5_128237 All targets in OG5_128237
Treponema pallidum polypeptide deformylase (def) Get druggable targets OG5_128237 All targets in OG5_128237
Chlamydia trachomatis peptide deformylase Get druggable targets OG5_128237 All targets in OG5_128237
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128237 All targets in OG5_128237
Plasmodium berghei peptide deformylase, putative Get druggable targets OG5_128237 All targets in OG5_128237
Wolbachia endosymbiont of Brugia malayi peptide deformylase Get druggable targets OG5_128237 All targets in OG5_128237
Plasmodium falciparum peptide deformylase Get druggable targets OG5_128237 All targets in OG5_128237
Plasmodium vivax peptide deformylase, putative Get druggable targets OG5_128237 All targets in OG5_128237
Mycobacterium ulcerans peptide deformylase Get druggable targets OG5_128237 All targets in OG5_128237
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) Get druggable targets OG5_128237 All targets in OG5_128237
Plasmodium yoelii polypeptide deformylase, putative Get druggable targets OG5_128237 All targets in OG5_128237
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis solute carrier family 5 0.0037 0.0218 0.0339
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Brugia malayi fructose-1,6-bisphosphatase 0.0308 0.241 0.7504
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0195 0.0371
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0762 0.3376
Loa Loa (eye worm) hypothetical protein 0.0026 0.0122 0.0332
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0063 0.0568
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0145 0.0479
Brugia malayi G protein-coupled receptor F59B2.13 0.0035 0.0195 0.0579
Brugia malayi Variant SH3 domain containing protein 0.0255 0.198 0.616
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0138 0.0443
Schistosoma mansoni protein kinase subunit gamma 0.0111 0.0815 0.079
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0034 0.0193 0.0361
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0145 0.1106
Echinococcus granulosus p2X purinoceptor 4 0.0531 0.4215 0.804
Schistosoma mansoni heat shock protein 0.003 0.016 0.0132
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0068 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Brugia malayi neuropeptide F receptor 0.0035 0.0195 0.0579
Toxoplasma gondii thioredoxin reductase 0.0046 0.0286 0.1088
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0056 0.0366 0.069
Trypanosoma brucei fructose-1,6-bisphosphatase 0.0308 0.241 0.4595
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0068 0.0182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0451 0.1915
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0043 0.007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0762 0.3462
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0138 0.0443
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.007 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0096 0.0069
Brugia malayi Dopamine receptor 0.0035 0.0195 0.0579
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0279 0.2172 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0068 0.004
Brugia malayi Serotonin receptor 0.0035 0.0195 0.0579
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0294 0.0457
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0138 0.0443
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0482 0.2061
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0106 0.0776 0.1474
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0138 0.0465
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0096 0.0898
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0195 0.0371
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0082 0.0149
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0068 0.0129
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0293 0.0455
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0674 0.2963
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0283 0.2724
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0038 0.0226 0.0431
Brugia malayi Cytochrome P450 family protein 0.0047 0.0298 0.0902
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0035 0.0195 0.0167
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Trypanosoma brucei Polypeptide deformylase 1 0.0106 0.0776 0.1474
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0294 0.0561
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0138 0.0255
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0028 0.0033
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0071 0.0135
Loa Loa (eye worm) hypothetical protein 0.0022 0.0094 0.0245
Echinococcus granulosus peter pan 0.0061 0.041 0.0782
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0195 0.0302
Leishmania major hypothetical protein, conserved 0.0658 0.5239 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0195 0.0302
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0068 0.0182
Loa Loa (eye worm) hypothetical protein 0.007 0.0482 0.1461
Plasmodium vivax heat shock protein 90, putative 0.003 0.016 0.0613
Echinococcus multilocularis neuropeptide receptor A26 0.0035 0.0195 0.0302
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0138 0.0443
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0117 0.086 0.1337
Loa Loa (eye worm) hypothetical protein 0.0028 0.0138 0.0383
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni adapter molecule crk 0.0017 0.0053 0.0026
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0294 0.0457
Trypanosoma brucei Peptide deformylase 2 0.0106 0.0776 0.1474
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0145 0.0479
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0145 0.0498
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0138 0.1028 0.4626
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0071 0.0173
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Entamoeba histolytica hypothetical protein 0.0019 0.0068 0.0618
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0195 0.0302
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Onchocerca volvulus 0.0035 0.0195 0.0491
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0145 0.0547
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0495 0.0468
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0063 0.0089
Entamoeba histolytica acyl-coA synthetase, putative 0.0094 0.0674 0.6543
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0929 0.2861
Echinococcus granulosus tar DNA binding protein 0.0125 0.0929 0.1772
Onchocerca volvulus 0.0028 0.0138 0.0335
Loa Loa (eye worm) hypothetical protein 0.0022 0.0096 0.0253
Loa Loa (eye worm) hypothetical protein 0.0028 0.0138 0.0383
Loa Loa (eye worm) endoplasmin 0.0046 0.0283 0.0838
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0053 0.0119
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Plasmodium falciparum peptide deformylase 0.0279 0.2172 1
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0111 0.0815 0.7855
Schistosoma mansoni intermediate filament proteins 0.0053 0.0343 0.0316
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0095 0.0683 0.2091
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0058 0.0387 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.007 0.0042
Toxoplasma gondii hypothetical protein 0.0048 0.0302 0.1156
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0138 0.0443
Onchocerca volvulus 0.0035 0.0195 0.0491
Schistosoma mansoni tyrosine kinase 0.0047 0.0294 0.0267
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0028 0.0057
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0063 0.027
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0063 0.0166
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0293 0.0558
Onchocerca volvulus 0.0035 0.0195 0.0491
Trypanosoma cruzi peter pan protein, putative 0.0061 0.041 0.0775
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0769 0.7466
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0167
Echinococcus granulosus tumor protein p63 0.0658 0.5243 1
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.0218 0.0339
Mycobacterium leprae Probable pyruvate kinase PykA 0.0132 0.0983 0.4487
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.0218 0.0803
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0043 0.0075
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0298 0.0884
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0094 0.0674 0.2963
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0138 0.0511
Toxoplasma gondii fructose-bisphospatase II 0.0308 0.241 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0035 0.0195 0.0302
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0308 0.241 0.4595
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0138 0.0443
Loa Loa (eye worm) loechrig isoform VII 0.0111 0.0815 0.2504
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0769 0.146
Chlamydia trachomatis peptide deformylase 0.0279 0.2172 1
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0283 0.0533
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0674 0.3054
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0068 0.004
Onchocerca volvulus 0.0028 0.0138 0.0335
Plasmodium vivax pyruvate kinase 2, putative 0.0068 0.0463 0.2029
Trypanosoma cruzi peter pan protein, putative 0.0061 0.041 0.0775
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0022 0.0096 0.0176
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0195 0.0302
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.016 0.1516
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0283 0.0533
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0293 0.0551
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0035 0.0195 0.0167
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.0014 0.0032 0.0053
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0856 0.382
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0016 0.0021
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0283 0.0533
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0352 0.0671
Brugia malayi Endoplasmin precursor 0.0046 0.0283 0.0856
Echinococcus granulosus sex peptide receptor 0.0035 0.0195 0.0371
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0028 0.000000026408
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0063 0.0147
Schistosoma mansoni growth hormone secretagogue receptor 0.0035 0.0195 0.0167
Onchocerca volvulus 0.0035 0.0195 0.0491
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0043 0.0068
Onchocerca volvulus 0.0037 0.0218 0.0555
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.007 0.019
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0043 0.0075
Schistosoma mansoni amine GPCR 0.0035 0.0195 0.0167
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0407 0.3208 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.037 0.0705
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0122 0.0232
Onchocerca volvulus 0.0035 0.0195 0.0491
Echinococcus granulosus expressed protein 0.0368 0.289 0.5513
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0138 0.0401
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) hypothetical protein 0.007 0.0482 0.1461
Schistosoma mansoni amine GPCR 0.0035 0.0195 0.0167
Echinococcus multilocularis musashi 0.0053 0.0343 0.0533
Echinococcus granulosus g-protein coupled receptor 0.0035 0.0195 0.0371
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0063 0.0089
Echinococcus granulosus NCK adaptor protein 0.0017 0.0053 0.0102
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0769 0.146
Brugia malayi TAR-binding protein 0.0125 0.0929 0.2875
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0138 0.1028 0.1955
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0261 0.102
Schistosoma mansoni pyruvate kinase 0.0068 0.0463 0.0437
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0138 0.1028 0.1003
Brugia malayi Dopamine receptor protein 2 0.0035 0.0195 0.0579
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0104 0.0759 0.118
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0043 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0015 0.0036 0.006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0035 0.0195 0.0561
Treponema pallidum polypeptide deformylase (def) 0.0279 0.2172 1
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0138 0.1028 0.1003
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0145 0.0498
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0293 0.1235
Echinococcus granulosus growth factor receptor bound protein 2 0.0017 0.0053 0.0102
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0035 0.0195 0.0167
Echinococcus granulosus fmrfamide receptor 0.0035 0.0195 0.0371
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Leishmania major pyruvate kinase 0.0132 0.0983 0.187
Loa Loa (eye worm) hypothetical protein 0.0025 0.0114 0.0307
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0063 0.0111
Plasmodium falciparum acyl-CoA synthetase 0.007 0.0482 0.2061
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0294 0.0457
Plasmodium vivax pyruvate kinase, putative 0.0132 0.0983 0.4455
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0071 0.0135
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.026 0.0782
Echinococcus multilocularis serotonin receptor 0.0035 0.0195 0.0302
Brugia malayi Sodium:solute symporter family protein 0.0037 0.0218 0.0653
Echinococcus granulosus neuropeptide s receptor 0.0035 0.0195 0.0371
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0043 0.026 0.0488
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0033 0.0181 0.0646
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0056 0.0366 0.069
Echinococcus multilocularis tyrosine protein kinase Abl 0.0018 0.0062 0.0096
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Onchocerca volvulus 0.0035 0.0195 0.0491
Onchocerca volvulus Alicorn homolog 0.0049 0.0309 0.0803
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0117 0.086 0.1641
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0068 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0658 0.5239 1
Entamoeba histolytica protein kinase, putative 0.003 0.0156 0.1478
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0195 0.0371
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.009 0.0644 0.1001
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0929 0.0904
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0035 0.0195 0.0561
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0058 0.0387 0.1512
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0643 0.1221
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0195 0.0167
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0036 0.021 0.0393
Schistosoma mansoni amine GPCR 0.0035 0.0195 0.0167
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0094 0.0674 0.2963
Echinococcus granulosus geminin 0.0333 0.2607 0.4972
Entamoeba histolytica hypothetical protein 0.0072 0.0495 0.479
Schistosoma mansoni peter pan-related 0.0061 0.041 0.0383
Onchocerca volvulus 0.0053 0.0343 0.0898
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0132 0.0983 0.4415
Schistosoma mansoni inositol transporter 0.0037 0.0218 0.0191
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0035 0.0195 0.0561
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0195 0.0371
Schistosoma mansoni protein kinase subunit beta 0.003 0.0157 0.0129
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0068 0.0105
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0283 0.119
Leishmania major pyruvate kinase 0.0132 0.0983 0.187
Trypanosoma brucei heat shock protein 84, putative 0.003 0.016 0.0296
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0769 0.7466
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0043 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0138 0.0255
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0145 0.027
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0035 0.0195 0.0167
Trypanosoma cruzi hypothetical protein 0.0658 0.5239 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0119
Onchocerca volvulus 0.0035 0.0195 0.0491
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) melatonin receptor type 1A 0.0035 0.0195 0.0561
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0138 0.1028 0.4664
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0293 0.0455
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0043 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0035 0.0195 0.0302
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0283 0.0533
Schistosoma mansoni amine GPCR 0.0035 0.0195 0.0167
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0016 0.0021
Echinococcus granulosus 7tm_1 domain containing protein 0.0035 0.0195 0.0371
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0293 0.1171
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0769 0.2358
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0762 0.3376
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0283 0.0838
Onchocerca volvulus 0.0035 0.0195 0.0491
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0063 0.0089
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0068 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0674 0.1279
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0022 0.0096 0.015
Schistosoma mansoni lipoxygenase 0.0019 0.0071 0.0043
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0294 0.0561
Brugia malayi phospholipase C homolog 0.0022 0.0093 0.0261
Loa Loa (eye worm) hypothetical protein 0.0036 0.021 0.0609
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0145 0.1379
Trypanosoma cruzi hypothetical protein, conserved 0.0658 0.5239 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0195 0.0167
Loa Loa (eye worm) hypothetical protein 0.0048 0.0302 0.0898
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0017 0.0053 0.0026
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0674 0.2078
Echinococcus granulosus 7TM GPCR rhodopsin 0.0035 0.0195 0.0371
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0674 0.6543
Schistosoma mansoni lamin 0.0053 0.0343 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus granulosus p2X purinoceptor 4 0.0531 0.4215 0.804
Trypanosoma cruzi hypothetical protein, conserved 0.0658 0.5239 1
Onchocerca volvulus 0.0035 0.0195 0.0491
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0293 0.0455
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Echinococcus granulosus G protein coupled receptor 139 0.0035 0.0195 0.0371
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0769 0.3407
Plasmodium falciparum heat shock protein 90, putative 0.0172 0.1311 0.5956
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0048 0.0302 0.0577
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0035 0.0195 0.0302
Entamoeba histolytica hypothetical protein 0.0072 0.0495 0.479
Loa Loa (eye worm) hypothetical protein 0.0132 0.0983 0.303
Plasmodium vivax endoplasmin, putative 0.0046 0.0283 0.119
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0195 0.0371
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0293 0.1116
Brugia malayi Pyruvate kinase, muscle isozyme 0.0132 0.0983 0.3044
Toxoplasma gondii pyruvate kinase PyK1 0.0132 0.0983 0.4013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0063 0.0111
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0071 0.011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus granulosus somatostatin receptor 0.0035 0.0195 0.0371
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0016 0.003
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0294 0.0561
Echinococcus multilocularis c src tyrosine kinase 0.0018 0.0062 0.0096
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0195 0.0302
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0035 0.0195 0.0579
Brugia malayi loechrig isoform VII 0.0111 0.0815 0.2519
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.003 0.0157 0.0243
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0016 0.0021
Entamoeba histolytica pyruvate kinase, putative 0.0092 0.066 0.6404
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0029 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0195 0.0302
Plasmodium falciparum endoplasmin, putative 0.0033 0.0182 0.0652
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.007 0.0109
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0769 0.3407
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0293 0.0455
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0071 0.011
Entamoeba histolytica hypothetical protein 0.0019 0.0068 0.0618
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0068 0.004
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0769 0.2358
Brugia malayi putative neuropeptide receptor NPR1 0.0035 0.0195 0.0579
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0138 0.0383
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0293 0.0551
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0182 0.034
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0195 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Onchocerca volvulus 0.0096 0.0695 0.1861
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0082 0.0149
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0018 0.0062 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0451 0.1915
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0043 0.0016
Echinococcus multilocularis p2X purinoceptor 4 0.0531 0.4215 0.6551
Echinococcus multilocularis g-protein coupled receptor 0.0035 0.0195 0.0302
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0115 0.0843 0.1601
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0293 0.1116
Schistosoma mansoni phospholipase C beta 0.0014 0.0032 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.023 0.0431
Schistosoma mansoni P2X receptor subunit 0.0531 0.4215 0.4199
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0117 0.086 0.2646
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Brugia malayi pyruvate kinase, muscle isozyme 0.0028 0.014 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Echinococcus multilocularis lamin 0.0053 0.0343 0.0533
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Loa Loa (eye worm) hypothetical protein 0.012 0.0884 0.2721
Giardia lamblia Kinase, CAMK CAMKL 0.0022 0.0096 0.061
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.0308 0.241 0.7499
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Leishmania major hypothetical protein, conserved 0.0014 0.0032 0.0053
Schistosoma mansoni hypothetical protein 0.0019 0.0071 0.0043
Onchocerca volvulus Huntingtin homolog 0.012 0.0884 0.2381
Schistosoma mansoni single-minded 0.0048 0.0303 0.0276
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.0983 0.2651
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.009 0.0644 0.1222
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0068 0.0105
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0138 0.0255
Schistosoma mansoni P2X receptor subunit 0.0531 0.4215 0.4199
Echinococcus multilocularis expressed protein 0.0368 0.289 0.4492
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0293 0.0551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Echinococcus multilocularis pyruvate kinase 0.0068 0.0463 0.072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0173
Trypanosoma brucei pyruvate kinase 1 0.0132 0.0983 0.187
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0769 0.146
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0071 0.011
Brugia malayi protein-tyrosine kinase 0.0038 0.0226 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0805 0.6435 1
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Chlamydia trachomatis pyruvate kinase 0.0132 0.0983 0.4415
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0034 0.0193 0.0704
Loa Loa (eye worm) pyruvate kinase 0.0132 0.0983 0.303
Echinococcus granulosus neuropeptide FF receptor 2 0.0035 0.0195 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Onchocerca volvulus 0.0036 0.021 0.0533
Brugia malayi intermediate filament protein 0.0053 0.0343 0.1044
Brugia malayi PAS domain containing protein 0.0048 0.0303 0.0917
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0182 0.034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Echinococcus granulosus neuropeptide receptor 0.0035 0.0195 0.0371
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0035 0.0195 0.0579
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.0308 0.241 0.3745
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0283 0.0533
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0138 0.0443
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0022 0.0093 0.0065
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.016 0.0304
Brugia malayi Pyruvate kinase, M2 isozyme 0.0132 0.0983 0.3044
Echinococcus granulosus tyrosine protein kinase Blk 0.0038 0.0226 0.0431
Leishmania major phospholipase c-like protein 0.0036 0.021 0.0393
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0022 0.0096 0.0318
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0293 0.0551
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0261 0.102
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Echinococcus granulosus neuropeptide receptor A26 0.0035 0.0195 0.0371
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0036 0.021 0.0769
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0043 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0095 0.0683 0.2091
Echinococcus multilocularis tumor protein p63 0.0658 0.5243 0.8148
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0106 0.0776 0.1474
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.023 0.1958
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0034 0.0193 0.0575
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.0217 0.0338
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.0217 0.0415
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0063 0.0111
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0015 0.0036 0.006
Echinococcus granulosus c src tyrosine kinase 0.0018 0.0062 0.0118
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0035 0.0195 0.0371
Echinococcus multilocularis endoplasmin 0.0043 0.0261 0.0405
Echinococcus multilocularis zinc finger protein 598 0.0061 0.0407 0.0632
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0047 0.0299 0.0904
Echinococcus multilocularis neuropeptide FF receptor 2 0.0035 0.0195 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0021
Echinococcus multilocularis pyruvate kinase 0.0068 0.0463 0.072
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0063 0.0111
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0022 0.0096 0.0176
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Brugia malayi heat shock protein 90 0.0046 0.0283 0.0856
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Onchocerca volvulus 0.0463 0.3664 1
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0167
Loa Loa (eye worm) Plcb4 protein 0.0034 0.0193 0.0557
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0068 0.0105
Echinococcus multilocularis NCK adaptor protein 0.0017 0.0053 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Brugia malayi MH2 domain containing protein 0.0117 0.086 0.2658
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0056 0.0366 0.3324
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0138 0.1028 0.4626
Schistosoma mansoni phospholipase C beta 0.0034 0.0193 0.0166
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0138 0.1028 0.4201
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0195 0.0167
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0674 0.2963
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0082 0.0228
Schistosoma mansoni neuropeptide receptor 0.0035 0.0195 0.0167
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Schistosoma mansoni hypothetical protein 0.0072 0.0495 0.0468
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0138 0.0255
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0929 0.0904
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0053 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0195 0.0302
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0145 0.027
Plasmodium vivax ubiquitin activating enzyme, putative 0.0048 0.0302 0.1279
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0202 0.0602
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0195 0.0302
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0138 0.1028 1
Onchocerca volvulus 0.0035 0.0195 0.0491
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0016 0.0021
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0138 0.0443
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0017 0.0053 0.0119
Treponema pallidum heat shock protein 90 0.0043 0.0261 0.102
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0035 0.0195 0.0302
Brugia malayi hypothetical protein 0.0161 0.1216 0.3771
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0068 0.0129
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0769 0.0743
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.023 0.0431
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.0218 0.0416
Loa Loa (eye worm) hypothetical protein 0.034 0.2665 0.8299
Trichomonas vaginalis pyruvate kinase, putative 0.0132 0.0983 0.187
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0138 0.1028 0.1955
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0769 0.146
Brugia malayi Death domain containing protein 0.0014 0.0028 0.0057
Schistosoma mansoni pyruvate kinase 0.0132 0.0983 0.0958
Onchocerca volvulus 0.0014 0.0032 0.0045
Leishmania major hypothetical protein, conserved 0.0056 0.0366 0.069
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0674 0.2963
Loa Loa (eye worm) TK protein kinase 0.003 0.0156 0.0439
Echinococcus granulosus dro:myosuppressin receptor 0.0035 0.0195 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0036 0.021 0.0609
Plasmodium falciparum pyruvate kinase 2 0.0068 0.0463 0.1972
Echinococcus granulosus heat shock protein 90 0.0046 0.0283 0.054
Loa Loa (eye worm) hypothetical protein 0.007 0.0482 0.1461
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0018 0.0062 0.0096
Toxoplasma gondii exonuclease III APE 0.0018 0.0063 0.015
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0255 0.198 0.6153
Onchocerca volvulus 0.0035 0.0195 0.0491
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0043 0.0075
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.026 0.0488
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0294 0.0457
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0343 0.1026
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0094 0.0674 0.2963
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0138 0.1028 0.1955
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0138 0.0255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.007 0.0134
Schistosoma mansoni sodium/solute symporter 0.0037 0.0218 0.0191
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0138 0.1028 0.1003
Brugia malayi Brix domain containing protein 0.0061 0.041 0.1252
Loa Loa (eye worm) hypothetical protein 0.012 0.0884 0.2721
Echinococcus multilocularis p2X purinoceptor 4 0.0531 0.4215 0.6551
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0138 0.0443
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0261 0.0489
Schistosoma mansoni neuropeptide receptor 0.0035 0.0195 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0028 0.0053
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0138 0.1303
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Brugia malayi G protein-coupled receptor 0.0035 0.0195 0.0579
Brugia malayi hypothetical protein 0.0019 0.0068 0.0182
Schistosoma mansoni endoplasmin 0.0046 0.0283 0.0256
Schistosoma mansoni histamine h1 receptor 0.0035 0.0195 0.0167
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0769 0.2358
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0068 0.0105
Loa Loa (eye worm) hypothetical protein 0.0036 0.021 0.0609
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0028 0.0038
Brugia malayi RE15519p 0.0035 0.0195 0.0579
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0047 0.0019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis heat shock protein 90 0.0039 0.023 0.0357
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0138 0.1028 0.4626
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0138 0.1028 0.4201
Loa Loa (eye worm) ThiF family protein 0.0032 0.017 0.0483
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0117 0.086 0.266
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0036 0.021 0.0393
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.0983 0.2651
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Echinococcus multilocularis neuropeptide s receptor 0.0035 0.0195 0.0302
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0016 0.0021
Trypanosoma brucei SNF1-related protein kinases, putative 0.0022 0.0096 0.0176
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0167
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0035 0.0195 0.0302
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Giardia lamblia Peter pan protein 0.0061 0.041 0.3772
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0035 0.0195 0.0491
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.0218 0.0339
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0261 0.0489
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0299 0.1202
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0068 0.0129
Loa Loa (eye worm) hypothetical protein 0.0052 0.0335 0.1001
Brugia malayi GnHR receptor homolog 0.0035 0.0195 0.0579
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0643 0.1221
Brugia malayi putative serine/threonine kinase SADA gamma 0.0022 0.0096 0.0272
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0107 0.0297
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0016 0.0021
Brugia malayi GH02984p 0.034 0.2665 0.8303
Echinococcus granulosus Ankyrin 0.0014 0.0029 0.0055
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0056 0.0366 0.1096
Toxoplasma gondii Hsp90 domain-containing protein 0.0172 0.1311 0.5389
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0674 0.1279
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0167
Loa Loa (eye worm) glutathione reductase 0.0046 0.0286 0.0848
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0294 0.0561
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0279 0.2172 1
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0138 0.1028 0.1955
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.023 0.0439
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0138 0.0443
Onchocerca volvulus Peter pan protein homolog 0.0061 0.041 0.1081
Loa Loa (eye worm) hypothetical protein 0.009 0.0644 0.1968
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0387 0.0361
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0294 0.0457
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0035 0.0195 0.0561
Brugia malayi pyruvate kinase 0.0028 0.014 0.0408
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0063 0.0119
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Echinococcus granulosus neuropeptide receptor 0.0035 0.0195 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0195 0.0302
Echinococcus granulosus heat shock protein 90 0.0039 0.023 0.0439
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0063 0.0089
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0035 0.0195 0.0302
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.009 0.0644 0.1222
Echinococcus granulosus serotonin receptor 0.0035 0.0195 0.0371
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0022 0.0096 0.0176
Brugia malayi G-protein coupled receptor 0.0035 0.0195 0.0579
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0195 0.0302
Brugia malayi neuropeptide F receptor 0.0035 0.0195 0.0579
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0286 0.0538
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0856 0.382
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0115 0.0843 0.3424
Trypanosoma cruzi pyruvate kinase 2, putative 0.0132 0.0983 0.187
Brugia malayi G-protein coupled receptor 0.0035 0.0195 0.0579
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.0218 0.0416
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0068 0.0163
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0071 0.0199
Leishmania major ubiquitin-activating enzyme-like protein 0.0032 0.017 0.0316
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0043 0.0075
Brugia malayi hypothetical protein 0.0019 0.0071 0.0192
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0929 0.0904
Plasmodium falciparum glutathione reductase 0.0046 0.0286 0.114
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0016 0.0021
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0032 0.017 0.0594
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0145 0.0479
Loa Loa (eye worm) TK protein kinase 0.0038 0.0226 0.0659
Echinococcus multilocularis dro:myosuppressin receptor 0.0035 0.0195 0.0302
Brugia malayi 6-phosphofructokinase 0.0105 0.0769 0.2373
Echinococcus granulosus pyruvate kinase 0.0068 0.0463 0.0883
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0138 0.0443
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0022 0.0096 0.0176
Brugia malayi PXA domain containing protein 0.0019 0.0068 0.0182
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0769 0.0743
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0035 0.0195 0.0302
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Echinococcus granulosus g protein coupled receptor 0.0035 0.0195 0.0371
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0387 0.0361
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0762 0.3376
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0032 0.017 0.0316
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0195 0.0371
Brugia malayi 6-phosphofructokinase 0.0105 0.0769 0.2373
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0283 0.0533
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0261 0.0489
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0293 0.1171
Echinococcus granulosus pyruvate kinase 0.0068 0.0463 0.0883
Schistosoma mansoni ap endonuclease 0.0018 0.0063 0.0035
Brugia malayi Melatonin receptor type 1A 0.0035 0.0195 0.0579
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0043 0.0107
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0195 0.0167
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0015 0.0036 0.0307
Echinococcus granulosus lamin 0.0053 0.0343 0.0655
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0138 0.0566
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.003 0.0157 0.0299
Trypanosoma cruzi hypothetical protein 0.0658 0.5239 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0138 0.0263
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0062 0.0087
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.086 0.2643
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Onchocerca volvulus 0.0028 0.0138 0.0335
Brugia malayi phosphofructokinase 0.0105 0.0769 0.2373
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0036 0.021 0.0401
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0068 0.0121
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0138 0.0443
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0035 0.0195 0.0167
Brugia malayi Serotonin receptor 0.0035 0.0195 0.0579
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0068 0.0129
Loa Loa (eye worm) RecQ helicase 0.0021 0.0082 0.0209
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0138 0.1028 0.1955
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni biogenic amine receptor 0.0035 0.0195 0.0167
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0035 0.0195 0.0371
Entamoeba histolytica hypothetical protein 0.0072 0.0495 0.479
Onchocerca volvulus 0.0028 0.0138 0.0335
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0082 0.0128
Echinococcus multilocularis RUN 0.0019 0.0071 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0096 0.0069
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0035 0.0195 0.0579
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0122 0.0189
Leishmania major trypanothione reductase 0.0046 0.0286 0.0538
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0286 0.1204
Onchocerca volvulus 0.0036 0.021 0.0533
Brugia malayi Tachykinin-like peptides receptor 99D 0.0035 0.0195 0.0579
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0138 0.011
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0293 0.0266
Brugia malayi Pre-SET motif family protein 0.0058 0.0387 0.1181
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0294 0.0561
Echinococcus granulosus orexin receptor type 2 0.0035 0.0195 0.0371
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0674 0.6543
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.0218 0.0416
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0856 0.39
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0138 0.0401
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.009 0.0644 0.1229
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0138 0.0443
Loa Loa (eye worm) RNA binding protein 0.0125 0.0929 0.2861
Brugia malayi PXA domain containing protein 0.0019 0.0068 0.0182
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0068 0.0182
Echinococcus granulosus tyrosine protein kinase HCK 0.003 0.0156 0.0297
Echinococcus granulosus solute carrier family 5 0.0037 0.0218 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.007 0.0042
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0035 0.0195 0.0167
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0195 0.0371
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Brugia malayi hypoxia-induced factor 1 0.0148 0.1115 0.3456
Echinococcus multilocularis heat shock protein 90 0.0046 0.0283 0.044
Loa Loa (eye worm) heat shock protein 75 0.003 0.016 0.0451
Schistosoma mansoni endoplasmin 0.0046 0.0283 0.0256
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0299 0.1316
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0038
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0115 0.0843 0.1601
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0115 0.0843 0.1601
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0138 0.1028 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0138 0.0383
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0226 0.0351
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.0218 0.0339
Schistosoma mansoni biogenic amine receptor 0.0035 0.0195 0.0167
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0129 0.0402
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0643 0.6125
Onchocerca volvulus 0.0035 0.0195 0.0491
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0138 0.0443
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0644 0.1968
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0138 0.0566
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0495 0.0769
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0068 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Schistosoma mansoni high-affinity choline transporter 0.034 0.2665 0.2645
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.016 0.0248
Echinococcus granulosus peptide allatostatin:somatostatin 0.0035 0.0195 0.0371
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0343 0.1044
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0195 0.0302
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0071 0.0135
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0018 0.0026
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0068 0.0105
Entamoeba histolytica brix domain containing protein 0.0061 0.041 0.3963
Echinococcus granulosus heat shock protein 0.0046 0.0283 0.054
Onchocerca volvulus 0.0035 0.0195 0.0491
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0769 0.1194
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0016 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0138 0.0401
Toxoplasma gondii histone kinase SNF1, putative 0.0022 0.0096 0.0291
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0493 0.0941
Loa Loa (eye worm) pyruvate kinase 0.0132 0.0983 0.303
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0068 0.0105
Brugia malayi hypothetical protein 0.0019 0.0071 0.0192
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0202 0.0314
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.0983 0.2651
Schistosoma mansoni neuropeptide receptor 0.0035 0.0195 0.0167
Entamoeba histolytica hypothetical protein 0.0019 0.0068 0.0618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0068 0.0129
Loa Loa (eye worm) TYRA-2 protein 0.0035 0.0195 0.0561
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0047 0.0299 0.0562
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0138 0.0401
Brugia malayi ThiF family protein 0.0032 0.017 0.0502
Loa Loa (eye worm) hypothetical protein 0.0022 0.0094 0.0245
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0068 0.004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0018 0.0026
Brugia malayi Tyrosine-protein kinase abl-1 0.0018 0.0062 0.0164
Echinococcus multilocularis allatostatin A receptor 0.0035 0.0195 0.0302
Loa Loa (eye worm) pyruvate kinase 0.0028 0.014 0.0389
Loa Loa (eye worm) hypothetical protein 0.0092 0.066 0.2018
Brugia malayi Dopamine receptor protein 1 0.0035 0.0195 0.0579
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Schistosoma mansoni opsin-like receptor 0.0035 0.0195 0.0167
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0018 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0035 0.0195 0.0371
Mycobacterium ulcerans peptide deformylase 0.0279 0.2172 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0195 0.0371
Echinococcus multilocularis AMPK beta subunit 0.0056 0.0366 0.0568
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0032 0.017 0.0324
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0279 0.2172 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0068 0.0182
Echinococcus granulosus zinc finger protein 598 0.0061 0.0407 0.0776
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0283 0.1076
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0032 0.017 0.0661
Loa Loa (eye worm) hypothetical protein 0.0034 0.0193 0.0557
Trypanosoma cruzi heat shock protein, putative 0.003 0.016 0.0296
Plasmodium falciparum thioredoxin reductase 0.0046 0.0286 0.114
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0138 0.1028 0.1955
Brugia malayi hypothetical protein 0.0072 0.0495 0.1517
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0043 0.026 0.0488
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0103
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.007 0.0482 0.2061
Onchocerca volvulus 0.0035 0.0195 0.0491
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0035 0.0195 0.0302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Entamoeba histolytica hypothetical protein 0.0072 0.0495 0.479
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0138 0.1028 0.4626
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Giardia lamblia Kinase, CAMK CAMKL 0.0022 0.0096 0.061
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.007 0.0171
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0138 0.0443
Onchocerca volvulus 0.0053 0.0343 0.0898
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0138 0.1028 0.1598
Echinococcus granulosus single minded 2 0.0035 0.0202 0.0385
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0195 0.0302
Leishmania major protein kinase, putative 0.0013 0.0018 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0929 0.0904
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0138 0.0255
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0014 0.0032 0.0052
Echinococcus granulosus fructose 16 bisphosphatase 1 0.0308 0.241 0.4597
Brugia malayi larval opioid receptor 0.0035 0.0195 0.0579
Schistosoma mansoni cellular tumor antigen P53 0.0096 0.0695 0.0669
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0068 0.0129
Schistosoma mansoni rab6-interacting 0.0019 0.0071 0.0043
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0032 0.017 0.0316
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0286 0.0848
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0195 0.0167
Toxoplasma gondii brix domain-containing protein 0.0061 0.041 0.1608
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0929 0.2875
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0138 0.0443
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.086 0.2643
Loa Loa (eye worm) hypothetical protein 0.0094 0.0674 0.2062
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0294 0.0457
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0035 0.0195 0.0561
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0138 0.1028 0.1955
Brugia malayi Hsp90 protein 0.003 0.016 0.047
Brugia malayi ORL1-like opioid receptor 0.0035 0.0195 0.0579
Trypanosoma cruzi hypothetical protein, conserved 0.0658 0.5239 1
Trichomonas vaginalis heat shock protein, putative 0.0039 0.023 0.0431
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0145 0.0479
Echinococcus granulosus RUN 0.0019 0.0071 0.0135
Brugia malayi hypothetical protein 0.012 0.0884 0.2735
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0769 0.3407
Echinococcus multilocularis Ankyrin 0.0014 0.0029 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Loa Loa (eye worm) hypothetical protein 0.0037 0.0218 0.0635
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0048 0.0302 0.1216
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0643 0.1221
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0034 0.0193 0.0361
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0144 0.0403
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0068 0.0105
Leishmania major polypeptide deformylase-like protein, putative 0.0106 0.0776 0.1474
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0138 0.1028 0.1003
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0068 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Loa Loa (eye worm) hypothetical protein 0.0058 0.0387 0.1164
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0028 0.0043
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0048 0.0302 0.047
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0451 0.1915
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Onchocerca volvulus 0.0035 0.0195 0.0491
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0145 0.0479
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0043 0.026 0.0488
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.0014 0.0032 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0068 0.004
Mycobacterium ulcerans hypothetical protein 0.0094 0.0674 0.2963
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0068 0.0163
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0043 0.0083
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0195 0.0167
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Schistosoma mansoni polycystin 1-related 0.0019 0.0071 0.0043
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0293 0.0868
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Echinococcus granulosus alpha 1A adrenergic receptor 0.0035 0.0195 0.0371
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0195 0.0167
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0202 0.0744
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0195 0.0167
Loa Loa (eye worm) SRC-1 0.0047 0.0294 0.0873
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0111 0.0815 0.1267
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0068 0.004
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0043 0.026 0.0488
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0138 0.0255
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0138 0.1028 1
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0195 0.0561
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0043 0.0261 0.102
Echinococcus multilocularis heat shock protein 0.0046 0.0283 0.044
Plasmodium vivax peptide deformylase, putative 0.0279 0.2172 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0303 0.0276
Trichomonas vaginalis ssf, putative 0.0061 0.041 0.0775
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0283 0.0533
Schistosoma mansoni P2X receptor subunit 0.0263 0.2047 0.2025
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0674 0.2078
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0929 0.0904
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0138 0.0443
Loa Loa (eye worm) hypothetical protein 0.0094 0.0674 0.2062
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0195 0.0302
Schistosoma mansoni ap endonuclease 0.0018 0.0063 0.0035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0068 0.0182
Echinococcus multilocularis tyrosine protein kinase HCK 0.003 0.0156 0.0242
Echinococcus multilocularis pyruvate kinase 0.0068 0.0463 0.072
Brugia malayi glutathione reductase 0.0046 0.0286 0.0865
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0195 0.0302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.007 0.0171
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.1115 0.3443
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0769 0.3492
Echinococcus granulosus tyrosine kinase 0.0038 0.0226 0.0431
Echinococcus multilocularis high affinity choline transporter 1 0.034 0.2665 0.4142
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0138 0.0443
Brugia malayi putative neuropeptide receptor 0.0035 0.0195 0.0579
Loa Loa (eye worm) hypothetical protein 0.0161 0.1216 0.3759
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0293 0.0551
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0063 0.016
Schistosoma mansoni fructose-16-bisphosphatase-related 0.0308 0.241 0.2389
Loa Loa (eye worm) oxidoreductase 0.0028 0.0138 0.0383
Echinococcus granulosus lamin dm0 0.0053 0.0343 0.0655
Leishmania major heat shock protein, putative 0.003 0.016 0.0296
Schistosoma mansoni tyrosine kinase 0.0018 0.0062 0.0034
Echinococcus multilocularis lamin dm0 0.0053 0.0343 0.0533
Leishmania major protein kinase, putative 0.0013 0.0018 0.0026
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0644 0.1968
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0929 0.1444
Brugia malayi isocitrate dehydrogenase 0.0047 0.0293 0.0886
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni myosin xvIII 0.0035 0.0195 0.0167
Plasmodium falciparum pyruvate kinase 0.0132 0.0983 0.4415
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0343 0.1026
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0145 0.0498
Onchocerca volvulus 0.0094 0.0674 0.1804
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0043 0.0075
Mycobacterium ulcerans pyruvate kinase 0.0132 0.0983 0.4415
Schistosoma mansoni hypothetical protein 0.0333 0.2607 0.2586
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0111 0.0815 0.1555
Brugia malayi phospholipase C homolog 0.0014 0.0032 0.0071
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0063 0.0111
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0283 0.1076
Brugia malayi hypothetical protein 0.0022 0.0094 0.0264
Echinococcus multilocularis pyruvate kinase 0.0104 0.0758 0.1178
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0068 0.0105
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0019 0.0069 0.0119
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0283 0.2724
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0053 0.0138
Brugia malayi Protein kinase domain containing protein 0.0014 0.003 0.0065
Trypanosoma cruzi Peptide deformylase 2, putative 0.0106 0.0776 0.1474
Plasmodium falciparum heat shock protein 90 0.0046 0.0283 0.1126
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0022 0.0096 0.0253
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0028 0.0043
Brugia malayi Uncoordinated protein 44 0.0014 0.0028 0.0057
Brugia malayi Pre-SET motif family protein 0.0407 0.3208 1
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Schistosoma mansoni inositol transporter 0.0037 0.0218 0.0191
Onchocerca volvulus 0.0035 0.0195 0.0491
Schistosoma mansoni tyrosine kinase 0.0047 0.0294 0.0267
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0145 0.0547
Onchocerca volvulus 0.0019 0.0071 0.0151
Giardia lamblia Grp94/Hsp90 0.0043 0.0261 0.2266
Toxoplasma gondii heat shock protein 75, putative 0.003 0.016 0.0557
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0022 0.0096 0.0176
Loa Loa (eye worm) hypothetical protein 0.0096 0.0695 0.2127
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0138 0.0214
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0138 0.1028 0.3184
Schistosoma mansoni P2X receptor subunit 0.0263 0.2047 0.2025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Schistosoma mansoni opsin-like receptor 0.0035 0.0195 0.0167
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0144 0.0422
Schistosoma mansoni tyrosine kinase 0.0018 0.0062 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0096 0.0069
Schistosoma mansoni peter pan-related 0.0061 0.041 0.0383
Toxoplasma gondii ThiF family protein 0.0032 0.017 0.06
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0094 0.0674 0.2963
Mycobacterium tuberculosis Probable reductase 0.0105 0.0762 0.3376
Schistosoma mansoni biogenic amine receptor 0.0035 0.0195 0.0167
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0762 0.3376
Echinococcus multilocularis somatostatin receptor 0.0035 0.0195 0.0302
Echinococcus granulosus tachykinin peptides receptor 99D 0.0035 0.0195 0.0371
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0283 0.2494
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.086 0.0835
Schistosoma mansoni pyruvate kinase 0.0132 0.0983 0.0958
Toxoplasma gondii pyruvate kinase PyKII 0.0068 0.0463 0.1831
Echinococcus multilocularis tyrosine protein kinase Srms 0.0038 0.0226 0.0351
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0138 0.0255
Echinococcus multilocularis peter pan 0.0061 0.041 0.0637
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0032 0.017 0.0143
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0036 0.021 0.0326
Schistosoma mansoni lipoxygenase 0.0054 0.0352 0.0325
Echinococcus multilocularis tyrosine protein kinase Blk 0.0038 0.0226 0.0351
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0195 0.0302
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0138 0.1028 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0132 0.0983 0.187
Echinococcus granulosus pyruvate kinase 0.0132 0.0983 0.1875
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0769 0.7466
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.009 0.0643 0.1221
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Loa Loa (eye worm) pyruvate kinase 0.0132 0.0983 0.303
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Echinococcus granulosus histone lysine methyltransferase setb 0.0058 0.0387 0.0739
Echinococcus granulosus hypothetical protein 0.0035 0.0195 0.0371
Trichomonas vaginalis set domain proteins, putative 0.0463 0.3664 0.699
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0068 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0195 0.0371
Echinococcus granulosus p2X purinoceptor 4 0.0531 0.4215 0.804
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0138 0.0443
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0674 0.3054
Echinococcus multilocularis geminin 0.0333 0.2607 0.4051
Echinococcus multilocularis sex peptide receptor 0.0035 0.0195 0.0302
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0856 0.382
Brugia malayi follicle stimulating hormone receptor 0.0035 0.0195 0.0579
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0016 0.003
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0071 0.0128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0035 0.0195 0.0579
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0035 0.0195 0.0167
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0308 0.241 0.4595
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0016 0.0024
Schistosoma mansoni rab6-interacting 0.0019 0.0071 0.0043
Echinococcus granulosus g protein coupled receptor 0.0035 0.0195 0.0371
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Plasmodium vivax heat shock protein, putative 0.0172 0.1311 0.5985
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0043 0.0075
Trypanosoma brucei nucleoside 2-deoxyribosyltransferase 0.0658 0.5239 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0283 0.0533
Trypanosoma brucei pyruvate kinase 1, putative 0.0132 0.0983 0.187
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0129 0.0238
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0043 0.0072
Echinococcus granulosus pyruvate kinase 0.0068 0.0463 0.0883
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0053 0.0138
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0068 0.004
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0014 0.0032 0.0004
Plasmodium vivax SET domain protein, putative 0.0058 0.0387 0.1675
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0056 0.0366 0.1113
Trypanosoma brucei heat shock protein, putative 0.0046 0.0283 0.0533
Echinococcus granulosus g protein coupled receptor 0.0035 0.0195 0.0371
Onchocerca volvulus 0.0035 0.0195 0.0491
Trypanosoma brucei trypanothione reductase 0.0046 0.0286 0.0538
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0043 0.0075
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0261 0.1136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0138 0.1028 0.1598
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0043 0.0075
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0063 0.0089
Loa Loa (eye worm) brix domain-containing protein 0.0061 0.041 0.1235
Giardia lamblia Pyruvate kinase 0.0132 0.0983 0.9548
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0018 0.0026
Schistosoma mansoni opsin-like receptor 0.0035 0.0195 0.0167
Toxoplasma gondii hypothetical protein 0.0279 0.2172 0.9
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0762 0.3376
Onchocerca volvulus 0.0035 0.0202 0.051
Loa Loa (eye worm) hypothetical protein 0.007 0.0482 0.1461
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0094 0.0674 0.2963
Brugia malayi ThiF family protein 0.0048 0.0302 0.0916
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0674 0.2078
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0016 0.0021
Schistosoma mansoni neuropeptide receptor 0.0035 0.0195 0.0167
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0293 0.0455
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0058 0.0387 0.0361
Onchocerca volvulus 0.0058 0.0387 0.1018
Onchocerca volvulus Neuropeptide F receptor homolog 0.0035 0.0195 0.0491
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0058 0.0387 0.0602
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0451 0.1915
Brugia malayi hypothetical protein 0.0035 0.0195 0.0579
Brugia malayi Thioredoxin reductase 0.0046 0.0286 0.0865
Echinococcus multilocularis pyruvate kinase 0.0132 0.0983 0.1528
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0138 0.0443
Schistosoma mansoni protein kinase subunit beta 0.0056 0.0366 0.0339
Plasmodium vivax glutathione reductase, putative 0.0046 0.0286 0.1204
Brugia malayi SRC-1 0.0047 0.0294 0.0891
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0048 0.0302 0.0275
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0035 0.0195 0.0167
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0138 0.0255
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0016 0.0021
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0138 0.1028 0.1955
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.0218 0.0416
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0195 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0056 0.0366 0.069
Plasmodium falciparum BRIX domain, putative 0.0061 0.041 0.1722
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0195 0.0302
Brugia malayi sulfakinin receptor protein 0.0035 0.0195 0.0579
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0138 0.1028 0.4626
Echinococcus granulosus allatostatin A receptor 0.0035 0.0195 0.0371
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0294 0.0457
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0138 0.0401
Schistosoma mansoni lamin 0.0053 0.0343 0.0316
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0195 0.0561
Onchocerca volvulus 0.0019 0.0071 0.0151
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Loa Loa (eye worm) hypothetical protein 0.0053 0.0343 0.1026
Plasmodium falciparum serine/threonine protein kinase KIN 0.0022 0.0096 0.0248
Brugia malayi Doublecortin family protein 0.0019 0.0071 0.0192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0387 0.0361
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0068 0.0129
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Schistosoma mansoni hypothetical protein 0.0333 0.2607 0.2586
Trichomonas vaginalis pyruvate kinase, putative 0.0132 0.0983 0.187
Brugia malayi hypothetical protein 0.0019 0.0068 0.0182
Schistosoma mansoni heat shock protein 0.0046 0.0283 0.0256
Plasmodium vivax hypothetical protein, conserved 0.0061 0.041 0.1781
Echinococcus multilocularis pyruvate kinase 0.0132 0.0983 0.1528
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0096 0.0069
Echinococcus multilocularis G protein coupled receptor 139 0.0035 0.0195 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Loa Loa (eye worm) hypothetical protein 0.0025 0.0114 0.0307
Echinococcus granulosus AMPK beta subunit 0.0056 0.0366 0.0697
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0286 0.0445
Schistosoma mansoni nck2/grb4 0.0017 0.0053 0.0026
Trypanosoma cruzi Peptide deformylase 2, putative 0.0106 0.0776 0.1474
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0056 0.0366 0.1113
Brugia malayi AKH receptor 0.0035 0.0195 0.0579
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0053 0.0026
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0027 0.0134 0.0248
Echinococcus granulosus bloom syndrome protein 0.0021 0.0082 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0138 0.1028 0.1961
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0016 0.0024
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0195 0.0561
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0043 0.0078
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0297 0.0566
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0032 0.017 0.0264
Trypanosoma brucei brix domain containing protein, putative 0.0061 0.041 0.0775
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0195 0.0561
Giardia lamblia Pyruvate kinase 0.0068 0.0463 0.4307
Schistosoma mansoni loxhd1 0.0019 0.0071 0.0043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0769 0.146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0195 0.0167
Schistosoma mansoni alpha-1 adrenergic receptor 0.0035 0.0195 0.0167
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0294 0.0457
Plasmodium vivax phospholipase C-like, putative 0.0034 0.0193 0.077
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0068 0.004
Brugia malayi RNA binding protein 0.0125 0.0929 0.2875
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0352 0.0547
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0096 0.0176
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0283 0.0533
Loa Loa (eye worm) hypothetical protein 0.007 0.0482 0.1461
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0138 0.0255
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0769 0.146
Onchocerca volvulus Huntingtin homolog 0.012 0.0884 0.2381
Echinococcus granulosus pyruvate kinase 0.0132 0.0983 0.1875
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0043 0.0075
Plasmodium vivax acyl-CoA synthetase, putative 0.007 0.0482 0.2118
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0495 0.0944
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0138 0.1028 0.1961
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.007 0.0482 0.2061
Leishmania major peter pan protein, putative 0.0061 0.041 0.0775
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0195 0.0302
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0769 0.1466
Echinococcus multilocularis growth factor receptor bound protein 2 0.0017 0.0053 0.0083
Echinococcus granulosus endoplasmin 0.0043 0.0261 0.0497
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0138 0.0255
Schistosoma mansoni amine GPCR 0.0035 0.0195 0.0167
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0286 0.0546
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0286 0.114
Echinococcus granulosus intermediate filament protein 0.0053 0.0343 0.0655
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0138 0.0443
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0294 0.0561
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0034 0.0193 0.0575
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0138 0.1028 0.1955
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0674 0.1279
Echinococcus granulosus high affinity choline transporter 1 0.034 0.2665 0.5084
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0769 0.146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0163
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0043 0.0267 0.024
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Leishmania major 0.0308 0.241 0.4595
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0294 0.0561
Echinococcus granulosus serine:threonine kinase SAD 1 0.0022 0.0096 0.0184
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0294 0.0457
Echinococcus multilocularis G-protein coupled receptor, putative 0.0035 0.0195 0.0302
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0138 0.0465
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0561
Brugia malayi Sex muscle abnormal protein 5 0.0017 0.0053 0.0138
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0929 0.2861
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0069 0.0124
Toxoplasma gondii fructose-bisphospatase I 0.0115 0.0843 0.3424
Echinococcus granulosus death domain containing protein 0.0014 0.0028 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0068 0.0121
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0195 0.0371
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0195 0.0302
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0138 0.0465
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0493 0.0766
Echinococcus multilocularis serotonin receptor 0.0035 0.0195 0.0302
Echinococcus multilocularis p2X purinoceptor 4 0.0531 0.4215 0.6551
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.016 0.0395
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0014 0.0032 0.0071
Leishmania major heat shock protein 83-1 0.0046 0.0283 0.0533
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0138 0.0401
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0035 0.0195 0.0579
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0063 0.0111
Schistosoma mansoni adenoreceptor 0.0035 0.0195 0.0167
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0227 0.1748 0.1726
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0293 0.0886
Schistosoma mansoni neuropeptide f receptor 76f 0.0035 0.0195 0.0167
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0195 0.0371
Loa Loa (eye worm) hypothetical protein 0.0094 0.0674 0.2062
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0138 0.0443
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0043 0.0075
Schistosoma mansoni heat shock protein 0.0046 0.0283 0.0256
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0674 0.2963
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0195 0.0167
Loa Loa (eye worm) pyruvate kinase-PB 0.0092 0.066 0.2018
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0018 0.0062 0.0118
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.0014 0.0032 0.0053
Echinococcus multilocularis orexin receptor type 2 0.0035 0.0195 0.0302
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0028 0.0053
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.004 0.0238 0.0715
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0138 0.0566
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0036 0.021 0.0627
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0173

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.87 uM Inhibition of the isolated native E. coli peptide deformylase (PDF) ChEMBL. 11384231
IC50 (binding) = 0.87 uM Inhibition of the isolated native E. coli peptide deformylase (PDF) ChEMBL. 11384231
MIC (functional) = 16 ug ml-1 In vitro antibacterial activity against Moraxella catarrhalis RA21 ChEMBL. 11384231
MIC (functional) > 64 ug ml-1 In vitro antibacterial activity against Escherichia coli ChEMBL. 11384231
MIC (functional) = 64 ug ml-1 In vitro antibacterial activity against Haemophilus influenzae 11 ChEMBL. 11384231
MIC (functional) > 64 ug ml-1 In vitro antibacterial activity against Escherichia coli ChEMBL. 11384231

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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