Detailed information for compound 869270

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 319.397 | Formula: C21H21NO2
  • H donors: 1 H acceptors: 2 LogP: 4.82 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccccc1/N=C\1/C(=O)C(=C1c1ccc(cc1)C(C)C)O
  • InChi: 1S/C21H21NO2/c1-4-14-7-5-6-8-17(14)22-19-18(20(23)21(19)24)16-11-9-15(10-12-16)13(2)3/h5-13,23H,4H2,1-3H3
  • InChiKey: WSSGGHGANSNKLU-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.023 0.0192 0.2182
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0037
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0018 0.0018
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0006 0.0013
Brugia malayi phosphofructokinase 0.0121 0.0094 0.1072
Entamoeba histolytica hypothetical protein 0.004 0.0022 0.0192
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0037
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0193 0.0158 0.1512
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.053 0.0459 0.5209
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0006 0.0112
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0006 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0039 0.0392
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0015 0.0116
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0005 0.0055
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0006 0.0065
Brugia malayi hypothetical protein 0.0182 0.0149 0.1691
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0007 0.0007
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0759 0.0664 0.7558
Loa Loa (eye worm) hypothetical protein 0.0193 0.0158 0.1362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.003 0.0013 0.0013
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0199 0.0164 0.1868
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0926 0.0814 0.2228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0525 0.0456 0.5165
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0015 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0119 0.0916
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0005 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0521 0.0452 0.512
Trichomonas vaginalis PIKK family atypical protein kinase 0.055 0.0478 0.5417
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Loa Loa (eye worm) hypothetical protein 0.0312 0.0265 0.2281
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0525 0.0456 0.1307
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0447 0.0385 0.1104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0193 0.0158 0.1756
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0041 0.0022 0.0725
Schistosoma mansoni hypothetical protein 0.0187 0.0153 0.1178
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0005 0.0005
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0018 0.0018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0947 0.0832 0.9487
Trypanosoma cruzi target of rapamycin kinase 3 0.0926 0.0814 0.2339
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0006 0.0065
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.0037 0.0281
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0006 0.0065
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0094 0.1065
Schistosoma mansoni hypothetical protein 0.0091 0.0067 0.0515
Loa Loa (eye worm) hypothetical protein 0.0564 0.049 0.4221
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0037
Echinococcus granulosus high voltage activated calcium channel beta 0.0097 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0015 0.0117
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0006 0.0112
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0037 0.0263
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0006 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.0269 0.3023
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.147 0.13 0.13
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0037
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0371 0.0318 0.0318
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0904 0.0794 0.0794
Brugia malayi Death domain containing protein 0.0016 0 0.0001
Onchocerca volvulus 0.0055 0.0035 0.1143
Echinococcus multilocularis musashi 0.003 0.0013 0.0012
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0022 0.0199
Echinococcus granulosus voltage dependent calcium channel 0.0036 0.0018 0.0018
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0034 0.0263
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0044
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.0037 0.0036
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0006 0.0112
Brugia malayi SH2 domain containing protein 0.0379 0.0325 0.3699
Brugia malayi PAS domain containing protein 0.0054 0.0034 0.039
Loa Loa (eye worm) hypothetical protein 0.0112 0.0086 0.0739
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0015 0.0116
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0892 0.0784 0.9409
Brugia malayi Casein kinase II, alpha chain 0.0153 0.0122 0.1393
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0068 0.0047 0.0129
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.0037 0.0351
Brugia malayi hypothetical protein 0.0021 0.0005 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0926 0.0814 0.9274
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0007 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0199 0.0164 0.1412
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0006 0.0112
Echinococcus multilocularis survival motor neuron protein 1 0.0525 0.0455 0.0455
Giardia lamblia Phosphatidylinositol 4-kinase 0.0193 0.0158 0.1751
Echinococcus multilocularis cyclin dependent kinase 19 0.0149 0.0119 0.0119
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.0037 0.0096
Schistosoma mansoni hypothetical protein 0.0107 0.0082 0.0626
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0 0.0001
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0193 0.0158 0.0158
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0027 0.0203
Loa Loa (eye worm) hypothetical protein 0.0112 0.0086 0.074
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0291 0.0246 1
Brugia malayi 6-phosphofructokinase 0.0121 0.0094 0.1072
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Loa Loa (eye worm) gastrulation defective protein 1 0.0145 0.0116 0.0997
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0358 0.0306 0.3486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0006 0.0065
Echinococcus multilocularis Zinc finger, PHD finger 0.0291 0.0246 0.0246
Leishmania major hypothetical protein, conserved 0.4095 0.3647 1
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0006 0.0054
Echinococcus granulosus casein kinase ii subunit alpha 0.0153 0.0122 0.0122
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0333 0.0283 0.081
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0008 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0039 0.0392
Giardia lamblia Kinase, PLK 0.0214 0.0177 0.1979
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0214 0.0177 0.048
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0738 0.0646 0.7362
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0006 0.0065
Loa Loa (eye worm) phosphatidylinositol 3 0.0892 0.0784 0.6749
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0234 0.0195 0.2282
Giardia lamblia Casein kinase II beta chain 0.0041 0.0022 0.0089
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Loa Loa (eye worm) hypothetical protein 0.0525 0.0455 0.392
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0008 0.0063
Brugia malayi hypothetical protein 0.0021 0.0005 0.0055
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0046 0.0027 0.0256
Echinococcus granulosus serine protein kinase ATM 0.0525 0.0456 0.0455
Onchocerca volvulus 0.0193 0.0158 0.5167
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0041 0.0022 0.0056
Toxoplasma gondii hypothetical protein 0.006 0.0039 0.0375
Onchocerca volvulus 0.0112 0.0086 0.2804
Echinococcus granulosus lamin dm0 0.003 0.0013 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0006 0.0065
Toxoplasma gondii hypothetical protein 0.0022 0.0005 0.005
Giardia lamblia Kinase, CMGC CK2 0.0153 0.0122 0.1312
Brugia malayi Protein kinase domain containing protein 0.0358 0.0306 0.3486
Schistosoma mansoni casein kinase II beta subunit 0.0041 0.0022 0.0171
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0068 0.0047 0.0358
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0214 0.0177 0.0177
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0037 0.0363
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0584 0.0508 0.6078
Brugia malayi Cytochrome P450 family protein 0.0044 0.0025 0.0286
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0075 0.0573
Loa Loa (eye worm) hypothetical protein 0.0055 0.0035 0.0302
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0025 0.0008 0.0071
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0947 0.0832 0.9484
Mycobacterium tuberculosis Conserved hypothetical protein 0.0193 0.0158 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0006 0.0112
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0018 0.0018
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0997 0.0877 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0006 0.0065
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0094 0.0094
Echinococcus granulosus beta-adrenergic receptor kinase 0.0025 0.0008 0.0008
Plasmodium vivax unspecified product 0.0153 0.0122 0.4964
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0291 0.0246 0.2906
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0509 0.0441 0.1265
Echinococcus granulosus expressed conserved protein 0.0091 0.0067 0.0067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0447 0.0385 0.4391
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0291 0.0246 0.0246
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0046 0.0027 0.0256
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0005 0.0055
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0291 0.0246 0.2807
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0947 0.0832 0.0832
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0006 0.0065
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0013 0.0089
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0193 0.0158 0.1756
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0036 0.0018 0.0201
Leishmania major phosphatidylinositol 3-kinase, putative 0.0291 0.0246 0.0671
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0068 0.0047 0.0046
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0094 0.0723
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0015 0.061
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0291 0.0246 0.0704
Brugia malayi FAT domain containing protein 0.0371 0.0318 0.362
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0997 0.0877 1
Echinococcus multilocularis lamin 0.003 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0564 0.049 0.556
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0094 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0036 0.0018 0.0018
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0947 0.0832 0.6403
Echinococcus multilocularis beta adrenergic receptor kinase 0.0025 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0015 0.1093
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0025 0.0008 0.0093
Toxoplasma gondii target of rapamycin (TOR), putative 0.0921 0.0809 0.7731
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0006 0.0065
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0497 0.0431 0.4878
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0358 0.0306 0.2635
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0035 0.0269
Loa Loa (eye worm) hypothetical protein 0.0182 0.0149 0.1278
Loa Loa (eye worm) hypothetical protein 0.0016 0 0.0002
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0447 0.0385 0.436
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0447 0.0385 0.436
Plasmodium falciparum casein kinase II beta chain 0.0041 0.0022 0.0743
Onchocerca volvulus 0.0057 0.0037 0.1193
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0006 0.0112
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0005 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.0193 0.0158 0.1362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0906 0.0796 0.9064
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0006 0.0065
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.0059 0.0059
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0015 0.0444
Schistosoma mansoni intermediate filament proteins 0.003 0.0013 0.0095
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Trypanosoma cruzi polo-like protein kinase, putative 0.0214 0.0177 0.0504
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0947 0.0832 0.0832
Leishmania major cytochrome p450-like protein 0.0033 0.0015 0.0036
Plasmodium falciparum GAF domain-related protein, putative 0.0022 0.0005 0.0035
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0358 0.0306 0.2635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0576 0.0501 0.568
Loa Loa (eye worm) hypothetical protein 0.0736 0.0644 0.5544
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0371 0.0318 0.0318
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0005 0.0042
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0193 0.0158 0.0158
Schistosoma mansoni hypothetical protein 0.0187 0.0153 0.1178
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0005
Schistosoma mansoni lamin 0.003 0.0013 0.0095
Onchocerca volvulus Serine\/threonine kinase homolog 0.0214 0.0177 0.5778
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0097 0.0072 0.0555
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0291 0.0246 0.1894
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0447 0.0385 0.436
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.0318 0.3585
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0842 0.0738 0.8407
Schistosoma mansoni lamin 0.003 0.0013 0.0095
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0291 0.0246 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0926 0.0814 0.9274
Loa Loa (eye worm) hypoxia-induced factor 1 0.0168 0.0136 0.117
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0177 0.136
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0736 0.0644 0.0643
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0006 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0153 0.0122 0.1345
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0193 0.0158 0.1802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0006 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0906 0.0796 0.9064
Schistosoma mansoni hypothetical protein 0.004 0.0022 0.0166
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Giardia lamblia Hypothetical protein 0.0193 0.0158 0.1751
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.0037 0.0036
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.0059 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.3902 0.3475 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0006 0.0065
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0015 0.0106
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Leishmania major casein kinase II, putative 0.0153 0.0122 0.0331
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0015 0.0015
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0936 0.0823 0.6331
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0291 0.0246 0.2767
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0291 0.0246 0.1894
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0015 0.5
Echinococcus multilocularis casein kinase ii subunit beta 0.0041 0.0022 0.0022
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.003 0.0013 0.0096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0013 0.0089
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0022 0.0022
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis PIKK family atypical protein kinase 0.055 0.0478 0.5417
Echinococcus granulosus protein kinase shaggy 0.0057 0.0037 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0006 0.0065
Leishmania major cytochrome p450-like protein 0.0023 0.0006 0.0012
Onchocerca volvulus 0.0107 0.0082 0.2662
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0068 0.0047 0.0129
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0509 0.0441 0.0441
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0 0.0000000037138
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0022 0.0199
Schistosoma mansoni hypothetical protein 0.0023 0.0006 0.0046
Leishmania major phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.0429
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0007 0.0078
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0013 0.0089
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0094 0.1023
Mycobacterium leprae putative cytochrome p450 0.0023 0.0006 0.0065
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0094 0.5815
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.0192 0.1649
Brugia malayi PXA domain containing protein 0.0023 0.0006 0.0071
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0005 0.0005
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0947 0.0832 0.9484
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0094 0.081
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0263 0.0221 0.1906
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0036 0.0018 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.0193 0.0158 0.1362
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.05 0.0433 0.3329
Leishmania major phosphatidylinositol kinase, putative 0.0193 0.0158 0.0429
Echinococcus multilocularis 0.0023 0.0006 0.0006
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0473 0.0408 0.4653
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0759 0.0664 0.7558
Brugia malayi M-phase phosphoprotein, mpp8 0.0112 0.0086 0.0978
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0099 0.0075 0.0074
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0006 0.0112
Schistosoma mansoni hypothetical protein 0.0371 0.0318 0.2443
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0564 0.049 0.4681
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0936 0.0823 0.0823
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0936 0.0823 0.0823
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0214 0.0177 0.1523
Plasmodium vivax hypothetical protein, conserved 0.0193 0.0158 0.642
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0254 0.0213 0.0608
Schistosoma mansoni ankyrin 23/unc44 0.0016 0 0.000000028574
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0521 0.0452 0.512
Plasmodium vivax SET domain protein, putative 0.0033 0.0015 0.0619
Leishmania major phosphatidylinositol 3-kinase, putative 0.088 0.0773 0.2115
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0013 0.0141
Plasmodium falciparum casein kinase 2, alpha subunit 0.0153 0.0122 0.4875
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0094 0.1023
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0892 0.0784 0.2144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0555 0.0482 0.547
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0997 0.0877 0.2521
Loa Loa (eye worm) RecQ helicase 0.0024 0.0007 0.0059
Plasmodium vivax casein kinase II beta chain, putative 0.0041 0.0022 0.0904
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0006 0.0112
Leishmania major phosphatidylinositol kinase related protein, putative 0.0209 0.0173 0.0469
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Echinococcus multilocularis 0.0193 0.0158 0.0158
Mycobacterium ulcerans putative regulatory protein 0.004 0.0022 0.1856
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0094 0.0266
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.184
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0006 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.0784 0.8924
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0015 0.0128
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.0037 0.1334
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0005
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0 0.0000000037138
Loa Loa (eye worm) phosphatidylinositol 3 0.0193 0.0158 0.1362
Brugia malayi Uncoordinated protein 44 0.0016 0 0.0001
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.0037 0.1484
Loa Loa (eye worm) phosphatidylinositol 3 0.0254 0.0213 0.1834
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0947 0.0832 0.9484
Trypanosoma cruzi polo-like protein kinase, putative 0.0214 0.0177 0.0504
Echinococcus multilocularis geminin 0.0187 0.0153 0.0153
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0041 0.0022 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0006 0.0065
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0291 0.0246 0.2767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0947 0.0832 0.9484
Onchocerca volvulus 0.004 0.0022 0.0705
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0358 0.0306 0.0306
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0333 0.0283 0.2439
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0068 0.0047 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0736 0.0644 0.0643
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.147 0.13 1
Brugia malayi cytochrome P450 0.0023 0.0006 0.0069
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0007 0.0023
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0804 0.0705 0.8025
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0068 0.0047 0.0129
Brugia malayi Protein kinase domain containing protein 0.0149 0.0119 0.1357
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0291 0.0246 0.0671
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0153 0.0122 0.4964
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0094 0.1023
Brugia malayi Pre-SET motif family protein 0.0033 0.0015 0.0174
Schistosoma mansoni voltage-gated cation channel 0.0036 0.0018 0.0136
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.088 0.0773 0.9279
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0037
Brugia malayi hypoxia-induced factor 1 0.0168 0.0136 0.1548
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0193 0.0158 0.1802
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0193 0.0158 0.0158
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0055
Echinococcus granulosus single minded 2 0.004 0.0022 0.0022
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0037
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0291 0.0246 0.2121
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0447 0.0385 0.436
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.045
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0193 0.0158 0.1756
Brugia malayi intracellular kinase 0.0057 0.0037 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.003 0.0013 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0193 0.0158 0.1362
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0509 0.0441 0.5025
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0015 0.0145
Echinococcus multilocularis expressed protein 0.0416 0.0358 0.0358
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0926 0.0814 0.9779
Onchocerca volvulus 0.0193 0.0158 0.5167
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0291 0.0246 0.0246
Echinococcus granulosus intermediate filament protein 0.003 0.0013 0.0012
Echinococcus multilocularis lamin dm0 0.003 0.0013 0.0012
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0097 0.0072 0.0072
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0936 0.0823 0.2364
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0068 0.0047 0.0478
Toxoplasma gondii FATC domain-containing protein 0.0525 0.0456 0.4352
Loa Loa (eye worm) phosphatidylinositol kinase 0.0193 0.0158 0.1362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0 0.0001
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0053 0.0033 0.0287
Onchocerca volvulus 0.0262 0.022 0.719
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0075 0.0573
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0997 0.0877 0.2521
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0193 0.0158 0.1216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0177 0.1966
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0094 0.1023
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0603 0.0525 0.6243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0525 0.0456 0.5439
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0525 0.0456 0.3504
Trichomonas vaginalis PIKK family atypical protein kinase 0.0926 0.0814 0.9274
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0947 0.0832 0.2391
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.088 0.0773 0.8801
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0348 0.0297 0.3451
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0947 0.0832 0.2391
Loa Loa (eye worm) hypothetical protein 0.0033 0.0015 0.0131
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0947 0.0832 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0006 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0358 0.0306 0.2353
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0068 0.0047 0.049
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0193 0.0158 0.6357
Schistosoma mansoni hypothetical protein 0.0057 0.0037 0.0283
Loa Loa (eye worm) hypothetical protein 0.0371 0.0318 0.2736
Brugia malayi bHLH-PAS transcription factor 0.004 0.0022 0.0246
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Loa Loa (eye worm) hypothetical protein 0.0509 0.0441 0.3798
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0094 0.0094
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0291 0.0246 0.2353
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0005
Brugia malayi Cytochrome P450 family protein 0.0033 0.0015 0.0169
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0291 0.0246 0.2767
Trichomonas vaginalis PIKK family atypical protein kinase 0.088 0.0773 0.8801
Entamoeba histolytica casein kinase, putative 0.0153 0.0122 0.1345
Schistosoma mansoni protein kinase 0.0153 0.0122 0.094
Brugia malayi hypothetical protein 0.0112 0.0086 0.0979
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0149 0.0119 0.1026
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.642
Echinococcus multilocularis casein kinase ii subunit alpha 0.0153 0.0122 0.0122
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0509 0.0441 0.0441
Trichomonas vaginalis PIKK family atypical protein kinase 0.088 0.0773 0.8801
Entamoeba histolytica hypothetical protein 0.0525 0.0456 0.5165
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0015 0.0128
Schistosoma mansoni hypothetical protein 0.0193 0.0158 0.1216
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0006 0.0065
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0997 0.0877 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0006 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Echinococcus multilocularis tumor protein p63 0.0377 0.0323 0.0322
Brugia malayi hypothetical protein 0.0525 0.0455 0.5187
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0006 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0037 0.0363
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0034
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0036 0.0018 0.0136
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0082 0.0881
Plasmodium vivax hypothetical protein 0.0193 0.0158 0.642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0379 0.0325 0.2796
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0015 0.0117
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0037 0.0315
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0094 0.1023
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0037 0.0363
Echinococcus granulosus lamin 0.003 0.0013 0.0012
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0082 0.0881
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Toxoplasma gondii cytochrome p450 superfamily protein 0.1187 0.1047 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0291 0.0246 0.2767
Toxoplasma gondii CMGC kinase, CK2 family 0.0153 0.0122 0.1169
Entamoeba histolytica hypothetical protein 0.0193 0.0158 0.1756
Schistosoma mansoni cytochrome P450 0.0023 0.0006 0.0046
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0068 0.0047 0.049
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0006 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0153 0.0122 0.1053
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0037 0.0363
Loa Loa (eye worm) intermediate filament protein 0.003 0.0013 0.0107
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0193 0.0158 0.1802
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0094 0.1023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0018 0.0152
Brugia malayi PXA domain containing protein 0.0023 0.0006 0.0071
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0006 0.0112
Loa Loa (eye worm) phosphatidylinositol 3 0.0947 0.0832 0.717
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0005 0.0037
Schistosoma mansoni single-minded 0.0054 0.0034 0.0263
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0015 0.0145
Loa Loa (eye worm) hypothetical protein 0.0029 0.0012 0.0102
Mycobacterium leprae conserved hypothetical protein 0.0193 0.0158 1
Echinococcus granulosus geminin 0.0187 0.0153 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0005 0.0042
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0094 0.081
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0041 0.0022 0.0214
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0015 0.061
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus multilocularis expressed conserved protein 0.0091 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0193 0.0158 0.1756
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0997 0.0877 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0015 0.0145
Entamoeba histolytica hypothetical protein 0.0193 0.0158 0.1756
Plasmodium vivax casein kinase II beta chain, putative 0.0041 0.0022 0.0904
Echinococcus granulosus casein kinase ii subunit beta 0.0041 0.0022 0.0022
Loa Loa (eye worm) cytochrome P450 0.0023 0.0006 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0015 0.0038
Entamoeba histolytica hypothetical protein 0.0842 0.0738 0.8407
Echinococcus multilocularis high voltage activated calcium channel beta 0.0097 0.0072 0.0072
Echinococcus multilocularis serine protein kinase ATM 0.0525 0.0456 0.0455
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0022 0.0166
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.0037 0.01
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0036 0.0018 0.0018
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0193 0.0158 0.1216
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0094 0.5815
Onchocerca volvulus 0.0112 0.0086 0.2804
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0013 0.0107
Onchocerca volvulus 0.003 0.0013 0.0403
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0936 0.0823 0.2364
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Echinococcus granulosus tumor protein p63 0.0377 0.0323 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0921 0.0809 0.9221
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0005 0.0005
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0003 0.0018
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0037
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0291 0.0246 0.2353
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0037 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Brugia malayi Cytochrome P450 family protein 0.0023 0.0006 0.0069
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0193 0.0158 0.1512
Entamoeba histolytica hypothetical protein 0.0193 0.0158 0.1756
Loa Loa (eye worm) Csnk2b protein 0.0041 0.0022 0.0192
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.1201 1 1
Brugia malayi 6-phosphofructokinase 0.0121 0.0094 0.1072
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0209 0.0173 0.0492
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0015 0.0444
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0005 0.0055
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0193 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0509 0.0441 0.4998
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0006 0.0112
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0005
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0094 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0018 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0006 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0015 0.0117
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0947 0.0832 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0046 0.0027 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0047 0.0478
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0005 0.0005
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0936 0.0823 0.9379
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0041 0.0022 0.0725
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0015 0.0128
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0094 0.1023
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0193 0.0158 0.045
Schistosoma mansoni survival motor neuron protein 0.0107 0.0082 0.0626
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0193 0.0158 0.642
Trichomonas vaginalis set domain proteins, putative 0.0262 0.022 0.2464
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0947 0.0832 0.2278
Brugia malayi follicle stimulating hormone receptor 0.0263 0.0221 0.2522
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0107
Schistosoma mansoni fkbp-rapamycin associated protein 0.0509 0.0441 0.3392
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0025 0.0008 0.0071
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0006 0.0112
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0025 0.0216
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.147 0.13 0.13
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0291 0.0246 0.0704
Onchocerca volvulus 0.003 0.0013 0.0403
Echinococcus granulosus expressed protein 0.0416 0.0358 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Trypanosoma cruzi casein kinase II, putative 0.0153 0.0122 0.0347
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0006 0.0112
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0036 0.0018 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0005 0.0208
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Entamoeba histolytica protein kinase rad3, putative 0.0509 0.0441 0.4998
Leishmania major hypothetical protein, unknown function 0.0193 0.0158 0.0429
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0358 0.0306 0.0306
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0015 0.0038
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0037 0.0315
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0947 0.0832 0.2278
Loa Loa (eye worm) phosphatidylinositol 3 0.1314 0.1161 1
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0039
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0447 0.0385 0.4589
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0022 0.0199
Entamoeba histolytica hypothetical protein 0.004 0.0022 0.0192
Echinococcus multilocularis protein kinase shaggy 0.0057 0.0037 0.0036
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0006 0.0013
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0193 0.0158 0.1512
Entamoeba histolytica protein kinase, putative 0.0057 0.0037 0.0363
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0358 0.0306 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0039 0.0392
Entamoeba histolytica serine/threonine protein kinase, putative 0.0214 0.0177 0.1971
Toxoplasma gondii GAF domain-containing protein 0.0022 0.0005 0.005
Brugia malayi hypothetical protein 0.004 0.0022 0.0246
Schistosoma mansoni kinase 0.011 0.0084 0.0647
Leishmania major cytochrome p450-like protein 0.0023 0.0006 0.0012
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0094 0.0723
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.003 0.0013 0.0143
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0193 0.0158 0.1216
Trichomonas vaginalis conserved hypothetical protein 0.0316 0.0269 0.3023
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0193 0.0158 0.045
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0006 0.0065
Toxoplasma gondii ck2 beta subunit 0.0041 0.0022 0.0214
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0193 0.0158 0.184
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0006 0.0065
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.0082 0.0928
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0041 0.0022 0.0059
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0006 0.0112
Trypanosoma brucei Casein kinase II 0.0153 0.0122 0.1405
Entamoeba histolytica hypothetical protein 0.004 0.0022 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0122 0.1345
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0006 0.0112
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0193 0.0158 0.0158
Trypanosoma brucei protein kinase, putative 0.0057 0.0037 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.088 0.0773 0.8801
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0006 0.0006
Toxoplasma gondii hypothetical protein 0.0022 0.0005 0.005
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0193 0.0158 0.1756
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0008 0.0063
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0291 0.0246 0.2767
Entamoeba histolytica hypothetical protein 0.004 0.0022 0.0192
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0006 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0901 0.0791 0.9011
Trichomonas vaginalis PIKK family atypical protein kinase 0.061 0.0531 0.6032
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0094 0.081
Echinococcus granulosus bloom syndrome protein 0.0024 0.0007 0.0007
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0094 1
Trypanosoma brucei polo-like protein kinase 0.0214 0.0177 0.2066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0926 0.0814 0.9274
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0926 0.0814 0.9274
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Brugia malayi Csnk2b protein 0.0041 0.0022 0.0253
Onchocerca volvulus 0.0046 0.0027 0.0865
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0006 0.0112
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0525 0.0456 0.5192
Giardia lamblia GTOR 0.0947 0.0832 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0041 0.0022 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0177 0.1971
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0018 0.0018
Brugia malayi Cytochrome P450 family protein 0.0033 0.0015 0.0169
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0068 0.0047 0.0478
Brugia malayi intermediate filament protein 0.003 0.0013 0.0141
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis PIKK family atypical protein kinase 0.055 0.0478 0.5417
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0006 0.0112
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0005
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0291 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Plasmodium falciparum casein kinase II beta chain 0.0041 0.0022 0.0743
Brugia malayi serine/threonine-protein kinase plk-2 0.0214 0.0177 0.2015
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0108
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0097 0.0072 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0068 0.0047 0.0478
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0193 0.0158 0.045
Brugia malayi Serotonin receptor 0.052 0.0451 0.5136
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0037
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0193 0.0158 0.6357
Echinococcus granulosus survival motor neuron protein 1 0.0525 0.0455 0.0455
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0022 0.0199
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0068 0.0047 0.0478
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0997 0.0877 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0042
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0015 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0947 0.0832 0.9484
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0013 0.0143
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0116
Echinococcus granulosus cyclin dependent kinase 19 0.0149 0.0119 0.0119
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0214 0.0177 0.0177
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0099 0.0075 0.0074
Loa Loa (eye worm) calcium channel 0.0036 0.0018 0.0152

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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