Detailed information for compound 939723

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.344 | Formula: C17H20N5O7P
  • H donors: 3 H acceptors: 6 LogP: -0.01 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H](CO[P@@]1(=O)OCc2c(O1)c(C)ccc2)OCn1cnc2c1nc(N)nc2O
  • InChi: 1S/C17H20N5O7P/c1-10-3-2-4-11-6-27-30(25,29-14(10)11)28-7-12(5-23)26-9-22-8-19-13-15(22)20-17(18)21-16(13)24/h2-4,8,12,23H,5-7,9H2,1H3,(H3,18,20,21,24)/t12-,30+/m0/s1
  • InChiKey: ZAYQPAHALAMQRS-IDPPAEMMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus granulosus casein kinase I gamma 0.009 0.0413 0.0391
Loa Loa (eye worm) AGC/PKG protein kinase 0.0132 0.0846 0.0901
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Brugia malayi G-protein coupled receptor 0.0467 0.4305 0.4642
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0251 0.207 0.2478
Plasmodium falciparum serine/threonine protein kinase 0.008 0.0309 0.2723
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0087 0.0375 0.1388
Echinococcus granulosus neuropeptide receptor 0.0467 0.4305 0.4292
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Schistosoma mansoni tyrosine kinase 0.0238 0.1943 0.3356
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Echinococcus granulosus roundabout 2 0.0119 0.0706 0.0685
Echinococcus granulosus casein kinase I alpha 0.0106 0.0576 0.0554
Trichomonas vaginalis STE family protein kinase 0.0083 0.034 0.1327
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0072 0.0221 0.024
Brugia malayi Casein kinase II, alpha chain 0.0098 0.0487 0.0512
Loa Loa (eye worm) TYRA-2 protein 0.0467 0.4305 0.4642
Echinococcus granulosus fmrfamide receptor 0.0467 0.4305 0.4292
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Giardia lamblia Kinase, CMGC MAPK 0.0081 0.0316 0.0154
Brugia malayi Protein kinase domain containing protein 0.0277 0.2343 0.252
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0263 0.2197 0.2632
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0081 0.0312 0.029
Echinococcus multilocularis serine:threonine protein kinase N2 0.0166 0.1193 0.1417
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0467 0.4305 0.5183
Echinococcus granulosus N chimaerin 0.0072 0.0221 0.0199
Echinococcus granulosus sex peptide receptor 0.0467 0.4305 0.4292
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus dual specificity 0.012 0.0717 0.0696
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0083 0.034 0.0384
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0087 0.0375 0.1612
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0398 0.3596 0.3581
Brugia malayi G protein-coupled receptor 0.0467 0.4305 0.4642
Trypanosoma brucei Casein kinase II 0.0098 0.0487 0.1828
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0717 0.1224
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.0187 0.0481
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Onchocerca volvulus 0.0068 0.0185 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0023 0.0017
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0214 0.1694 0.1675
Echinococcus multilocularis nervana 2 0.0125 0.0766 0.09
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Loa Loa (eye worm) casein kinase 0.0061 0.0104 0.0098
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.0187 0.0775
Plasmodium vivax unspecified product 0.0098 0.0487 0.4407
Loa Loa (eye worm) TK/FAK protein kinase 0.0555 0.5214 0.5626
Brugia malayi Protein kinase domain containing protein 0.0199 0.1535 0.1647
Onchocerca volvulus 0.0467 0.4305 0.8407
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0132 0.0846 0.0997
Brugia malayi neuropeptide F receptor 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus neuropeptides capa receptor 0.0467 0.4305 0.4292
Entamoeba histolytica PH domain containing protein kinase, putative 0.0118 0.07 0.1983
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.012 0.0717 0.3135
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0576 0.0669
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0061 0.0111 0.0106
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.075 0.7229 0.5
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0157 0.1102 0.4823
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.1044 0.4591
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.0187 0.0647
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0221 0.1759 0.2102
Echinococcus multilocularis casein kinase I delta 0.0106 0.0576 0.0669
Loa Loa (eye worm) hypothetical protein 0.0306 0.2639 0.2841
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0345 0.3043 0.3277
Echinococcus multilocularis calcium activated potassium channel 0.0133 0.0849 0.1
Schistosoma mansoni biogenic amine receptor 0.0467 0.4305 0.7461
Echinococcus granulosus nervana 2 0.0125 0.0766 0.0745
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0113 0.0643 0.0751
Schistosoma mansoni tyrosine kinase 0.036 0.3196 0.5533
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0214 0.1694 0.2023
Echinococcus multilocularis protein kinase shaggy 0.0078 0.0286 0.0318
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0111 0.0621 0.2707
Loa Loa (eye worm) hypothetical protein 0.009 0.0408 0.0427
Schistosoma mansoni neuropeptide F-like receptor 0.0467 0.4305 0.7461
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0143 0.0953 0.1126
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0375 0.063
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0467 0.4305 0.4642
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0184 0.1379 0.1478
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0113 0.0642 0.1093
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0846 0.1448
Loa Loa (eye worm) hypothetical protein 0.0465 0.4285 0.4621
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0082 0.0326 0.1392
Brugia malayi Protein kinase domain containing protein 0.0068 0.0185 0.0186
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0113 0.0642 0.1093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0467 0.4305 0.7461
Brugia malayi casein kinase 1, delta 0.0106 0.0576 0.0609
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0111 0.0106
Entamoeba histolytica protein kinase, putative 0.0083 0.034 0.0928
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0379 0.1479
Loa Loa (eye worm) TK/ALK protein kinase 0.0277 0.2342 0.2519
Brugia malayi protein unc-22 0.0054 0.0037 0.0026
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0113 0.0642 0.2799
Brugia malayi Protein kinase domain containing protein 0.0166 0.1193 0.1277
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0214 0.1694 0.1675
Brugia malayi Protein kinase domain containing protein 0.0215 0.1704 0.1829
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0155 0.1076 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0269 0.226 0.243
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Echinococcus granulosus g protein coupled receptor 0.0467 0.4305 0.4292
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0209 0.1642 0.1762
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Echinococcus multilocularis dual specificity protein kinase clk2 0.0152 0.1044 0.1237
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0081 0.0316 0.1156
Echinococcus multilocularis mitogen activated protein kinase 3 0.0081 0.0316 0.0355
Brugia malayi Dopamine receptor protein 2 0.0467 0.4305 0.4642
Echinococcus multilocularis myosin iiia 0.0082 0.0326 0.0367
Schistosoma mansoni protein kinase 0.0069 0.0187 0.0303
Onchocerca volvulus 0.0065 0.0144 0.0213
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0495 0.4595 0.4582
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0111 0.0106
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0467 0.4305 0.4292
Plasmodium vivax serine/threonine protein kinase, putative 0.008 0.0309 0.2723
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0076 0.0265 0.0439
Onchocerca volvulus 0.0068 0.0185 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.053 0.0899
Loa Loa (eye worm) TK protein kinase 0.0255 0.2118 0.2276
Entamoeba histolytica protein kinase, putative 0.0078 0.0286 0.077
Brugia malayi hypothetical protein 0.0057 0.0065 0.0057
Brugia malayi Protein kinase c protein 2 0.0113 0.0649 0.0688
Onchocerca volvulus 0.0324 0.2831 0.5505
Echinococcus granulosus tyrosine protein kinase Src42A 0.0159 0.1122 0.1102
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0643 0.251
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Entamoeba histolytica protein kinase, putative 0.008 0.0309 0.084
Plasmodium falciparum NIMA related kinase 1 0.0134 0.0862 0.7973
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.075 0.7229 0.5
Brugia malayi Egg laying defective protein 4 0.0132 0.0846 0.0901
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Schistosoma mansoni vam6/vps39 related 0.0113 0.0642 0.1093
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0191 0.1452 0.2788
Onchocerca volvulus 0.0467 0.4305 0.8407
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0157 0.1102 0.1177
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0106 0.0576 0.0609
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0394 0.3551 0.3536
Echinococcus granulosus cGMP dependent protein kinase 1 0.0132 0.0846 0.0825
Echinococcus granulosus Glutaredoxin protein 5 0.0125 0.0766 0.0745
Echinococcus multilocularis raf serine:threonine protein kinase 0.0081 0.0313 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0621 0.1058
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0394 0.3551 0.3827
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Echinococcus multilocularis aurora kinase A 0.0143 0.0959 0.1134
Echinococcus granulosus neuroglian 0.0093 0.044 0.0418
Entamoeba histolytica protein kinase, putative 0.008 0.0309 0.084
Loa Loa (eye worm) protein kinase domain-containing protein 0.009 0.0413 0.0433
Echinococcus granulosus 7tm_1 domain containing protein 0.0467 0.4305 0.4292
Brugia malayi Protein kinase domain containing protein 0.0152 0.1044 0.1116
Schistosoma mansoni tyrosine kinase 0.0444 0.4071 0.7055
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0216 0.1711 0.1837
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.226 0.3906
Schistosoma mansoni amine GPCR 0.0467 0.4305 0.7461
Schistosoma mansoni vesicular amine transporter 0.0076 0.0265 0.0439
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0113 0.0642 0.2799
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.1102 0.4845
Brugia malayi RE15519p 0.0467 0.4305 0.4642
Trichomonas vaginalis STE family protein kinase 0.0083 0.034 0.1327
Loa Loa (eye worm) hypothetical protein 0.012 0.0717 0.0761
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0061 0.0111 0.017
Schistosoma mansoni protein kinase 0.0053 0.0023 0.0017
Loa Loa (eye worm) hypothetical protein 0.0057 0.0065 0.0057
Loa Loa (eye worm) TK/EPH protein kinase 0.0121 0.0727 0.0773
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0083 0.0339 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0467 0.4305 0.7461
Trypanosoma brucei cdc2-related kinase 1 0.0116 0.0681 0.2595
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0083 0.034 0.0318
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trypanosoma cruzi casein kinase, putative 0.0106 0.0576 0.2505
Entamoeba histolytica serine/threonine protein kinase, putative 0.0269 0.226 0.6551
Brugia malayi MAP kinase sur-1 0.0081 0.0316 0.0328
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0191 0.1452 0.1557
Trypanosoma cruzi aurora B kinase, putative 0.0143 0.0959 0.4213
Schistosoma mansoni protein kinase 0.0053 0.0023 0.0017
Loa Loa (eye worm) TK protein kinase 0.0098 0.0488 0.0514
Trypanosoma cruzi Protein kinase B 0.0162 0.1154 0.508
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0159 0.1122 0.1102
Brugia malayi SH2 domain containing protein 0.0068 0.0185 0.0186
Schistosoma mansoni histamine h1 receptor 0.0467 0.4305 0.7461
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.008 0.0309 0.1282
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0191 0.1452 0.1433
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.012 0.0717 0.2736
Brugia malayi Dopamine receptor 0.0467 0.4305 0.4642
Trichomonas vaginalis CMGC family protein kinase 0.0152 0.1044 0.4078
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0162 0.1154 0.508
Trypanosoma brucei casein kinase I, isoform 2 0.0106 0.0576 0.2179
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0095 0.0456 0.0434
Loa Loa (eye worm) hypothetical protein 0.014 0.0923 0.0985
Schistosoma mansoni growth factor receptor-bound protein 0.0061 0.0111 0.017
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0959 0.3747
Schistosoma mansoni protein kinase 0.0062 0.0114 0.0175
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0068 0.0182 0.0192
Leishmania major protein kinase, putative 0.0143 0.0959 0.4187
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0191 0.1452 0.173
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0052 0.0013 0.005
Onchocerca volvulus 0.0467 0.4305 0.8407
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0111 0.0621 0.5685
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0113 0.0642 0.2439
Echinococcus granulosus tyrosine kinase 0.0068 0.0185 0.0163
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0467 0.4305 0.4292
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.1044 0.4591
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0081 0.0316 0.1193
Onchocerca volvulus Neuropeptide F receptor homolog 0.0467 0.4305 0.8407
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0201 0.1555 0.1855
Brugia malayi casein kinase I 0.0106 0.0576 0.0609
Brugia malayi Protein kinase domain containing protein 0.0068 0.0185 0.0186
Trypanosoma brucei SNF1-related protein kinases, putative 0.0087 0.0375 0.1388
Loa Loa (eye worm) AGC/PKA protein kinase 0.0111 0.0621 0.0658
Plasmodium falciparum protein kinase, putative 0.0069 0.0187 0.1561
Trypanosoma brucei protein kinase, putative 0.0069 0.0187 0.0647
Echinococcus granulosus neuropeptide FF receptor 2 0.0467 0.4305 0.4292
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0191 0.1452 0.1557
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0375 0.063
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0286 0.1115
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0251 0.207 0.2225
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0413 0.0696
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0221 0.0361
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0157 0.1102 0.4251
Loa Loa (eye worm) SRC-1 0.0159 0.1122 0.1199
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.1694 0.2923
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) TK/EGFR protein kinase 0.0608 0.5765 0.6221
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0467 0.4305 0.7461
Trichomonas vaginalis AGC family protein kinase 0.0111 0.0621 0.2426
Echinococcus granulosus Immunoglobulin 0.0076 0.0265 0.0243
Brugia malayi larval opioid receptor 0.0467 0.4305 0.4642
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0576 0.2248
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0249 0.2055 0.2461
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0078 0.0288 0.1077
Echinococcus multilocularis roundabout 2 0.0119 0.0706 0.0827
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0199 0.1535 0.1516
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0116 0.0681 0.2678
Schistosoma mansoni nephrin 0.01 0.0515 0.0873
Echinococcus granulosus serine:threonine protein kinase 0.0112 0.0633 0.0611
Echinococcus multilocularis Glutaredoxin protein 5 0.0125 0.0766 0.09
Echinococcus multilocularis fmrfamide receptor 0.0467 0.4305 0.5183
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0316 0.1234
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0068 0.0185 0.0163
Loa Loa (eye worm) hypothetical protein 0.0601 0.5695 0.6146
Loa Loa (eye worm) hypothetical protein 0.0113 0.0642 0.068
Echinococcus granulosus g protein coupled receptor 0.0467 0.4305 0.4292
Echinococcus granulosus serine:threonine protein kinase 3 0.0256 0.212 0.2102
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0162 0.115 0.123
Leishmania major protein kinase A catalytic subunit 0.0111 0.0621 0.2675
Loa Loa (eye worm) thyroid receptor interactor 0.0104 0.0551 0.0582
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0079 0.0292 0.027
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0166 0.1193 0.1173
Echinococcus multilocularis N chimaerin 0.0072 0.0221 0.024
Schistosoma mansoni opsin-like receptor 0.0467 0.4305 0.7461
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0214 0.1694 0.2023
Echinococcus multilocularis neuropeptide receptor 0.0467 0.4305 0.5183
Echinococcus multilocularis rac serine:threonine kinase 0.0162 0.1154 0.137
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0116 0.0681 0.0723
Echinococcus granulosus tyrosine protein kinase Src64B 0.0159 0.1122 0.1102
Brugia malayi AKH receptor 0.0467 0.4305 0.4642
Echinococcus granulosus tm gpcr rhodopsin 0.0467 0.4305 0.4292
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0076 0.0265 0.0439
Entamoeba histolytica protein kinase, putative 0.0143 0.0959 0.2743
Echinococcus multilocularis cyclin dependent kinase 1 0.0116 0.0681 0.0797
Trichomonas vaginalis AGC family protein kinase 0.0166 0.1193 0.466
Schistosoma mansoni tyrosine kinase 0.0608 0.5765 1
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.4305 0.5183
Brugia malayi Stress-activated protein kinase jnk-1 0.0263 0.2197 0.2362
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0159 0.1122 0.133
Loa Loa (eye worm) hypothetical protein 0.0103 0.0539 0.0569
Echinococcus multilocularis ephrin type A receptor 4 A 0.0103 0.0545 0.0632
Plasmodium falciparum casein kinase 2, alpha subunit 0.0098 0.0487 0.4407
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0366 0.3265 0.325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0072 0.0221 0.0199
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0116 0.0681 0.066
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.1102 0.4845
Schistosoma mansoni neuropeptide receptor 0.0467 0.4305 0.7461
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0601 0.5695 0.6146
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0112 0.0633 0.067
Echinococcus multilocularis somatostatin receptor 0.0467 0.4305 0.5183
Echinococcus granulosus neuropeptide Y receptor 0.0467 0.4305 0.4292
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0681 0.2661
Schistosoma mansoni protein kinase 0.0191 0.1453 0.2503
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0087 0.0375 0.1575
Schistosoma mansoni growth factor receptor-bound protein 0.0061 0.0111 0.017
Brugia malayi GnHR receptor homolog 0.0467 0.4305 0.4642
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1044 0.1793
Schistosoma mansoni tyrosine kinase 0.0068 0.0185 0.0299
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0083 0.0339 0.1415
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0467 0.4305 0.7461
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0132 0.0846 0.0997
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0452 0.4146 0.4133
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0277 0.2346 0.2813
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0068 0.0182 0.0159
Schistosoma mansoni protein kinase 0.0151 0.1039 0.1784
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1892 0.3267
Echinococcus multilocularis CDC7 cell division cycle 7 0.0087 0.0379 0.0431
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0111 0.0621 0.2358
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0467 0.4305 0.5183
Echinococcus multilocularis tyrosine protein kinase shark 0.0068 0.0185 0.0197
Brugia malayi serine/threonine-protein kinase 6 0.0143 0.0959 0.1024
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Echinococcus multilocularis 0.0151 0.1039 0.1231
Brugia malayi Cam kinase protein 1 0.0053 0.0023 0.0011
Loa Loa (eye worm) hypothetical protein 0.0076 0.0265 0.0273
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0166 0.1193 0.1173
Schistosoma mansoni protein kinase 0.0366 0.3265 0.5654
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0082 0.0326 0.1392
Giardia lamblia Kinase, NEK 0.0134 0.0862 0.292
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0079 0.0292 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0194 0.1485 0.58
Entamoeba histolytica protein kinase, putative 0.0068 0.0182 0.0466
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0058 0.0079 0.0308
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.06
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0054 0.0037 0.0026
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0087 0.0375 0.0392
Schistosoma mansoni tyrosine kinase 0.036 0.3196 0.5533
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0221 0.0361
Brugia malayi Temporarily assigned gene name protein 59 0.013 0.0822 0.0875
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0143 0.0953 0.0932
Schistosoma mansoni nck2/grb4 0.0061 0.0111 0.017
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.1102 0.1306
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0078 0.0286 0.1069
Trypanosoma brucei cdc2-related kinase 3 0.0116 0.0681 0.2595
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.008 0.0309 0.1166
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Entamoeba histolytica protein kinase, putative 0.012 0.0717 0.2034
Entamoeba histolytica protein kinase, putative 0.012 0.0717 0.2034
Giardia lamblia Kinase, AGC AKT 0.0115 0.0663 0.1914
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.008 0.0309 0.132
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.4305 0.5183
Echinococcus granulosus protein kinase 0.0151 0.1039 0.1019
Loa Loa (eye worm) AUR protein kinase 0.0143 0.0959 0.1024
Echinococcus granulosus mitogen activated protein kinase 14 0.0157 0.1102 0.1081
Onchocerca volvulus 0.0467 0.4305 0.8407
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0111 0.0621 0.2358
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0269 0.226 1
Brugia malayi Protein kinase domain containing protein 0.0068 0.0185 0.0186
Brugia malayi Protein kinase domain containing protein 0.0079 0.0292 0.0302
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0106 0.0576 0.2505
Echinococcus multilocularis expressed conserved protein 0.0132 0.0846 0.0997
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0495 0.4595 0.5535
Schistosoma mansoni biogenic amine (5HT) receptor 0.0467 0.4305 0.7461
Brugia malayi sulfakinin receptor protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0071 0.0213 0.0217
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0286 0.077
Plasmodium vivax serine/threonine kinase-1, putative 0.0152 0.1044 0.9704
Echinococcus granulosus protein kinase c epsilon type 0.0209 0.1642 0.1623
Echinococcus granulosus protein kinase shaggy 0.0078 0.0286 0.0263
Echinococcus granulosus titin 0.0054 0.0037 0.0014
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0467 0.4305 0.8407
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0166 0.1193 0.1417
Trypanosoma cruzi polo-like protein kinase, putative 0.0269 0.226 1
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0113 0.0643 0.0621
Schistosoma mansoni tyrosine kinase 0.0398 0.3596 0.6229
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0201 0.1555 0.1668
Brugia malayi Protein kinase domain containing protein 0.009 0.0413 0.0433
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.012 0.0717 0.0762
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Entamoeba histolytica protein kinase, putative 0.006 0.0095 0.021
Brugia malayi Temporarily assigned gene name protein 59 0.0113 0.0642 0.068
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Echinococcus granulosus tyrosine protein kinase Fyn 0.0159 0.1122 0.1102
Loa Loa (eye worm) melatonin receptor type 1A 0.0467 0.4305 0.4642
Brugia malayi Variant SH3 domain containing protein 0.0072 0.0221 0.0225
Echinococcus granulosus activin receptor type 0.0069 0.0187 0.0165
Trypanosoma brucei rac serine-threonine kinase, putative 0.0298 0.2561 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0467 0.4305 0.5183
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0116 0.0681 0.2945
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.2831 0.49
Onchocerca volvulus 0.0194 0.148 0.2844
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis protein tyrosine kinase 0.0549 0.5151 0.6209
Schistosoma mansoni atypical protein kinase C 0.0298 0.2556 0.4422
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.0037 0.0026
Brugia malayi Fes/CIP4 homology domain containing protein 0.0104 0.0551 0.0582
Loa Loa (eye worm) AUR protein kinase 0.0143 0.0959 0.1024
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0116 0.0681 0.0723
Echinococcus granulosus epidermal growth factor receptor 0.0608 0.5765 0.5755
Brugia malayi Protein kinase domain containing protein 0.0087 0.0379 0.0396
Onchocerca volvulus 0.0467 0.4305 0.8407
Onchocerca volvulus 0.0076 0.0266 0.0452
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0152 0.1044 0.4154
Echinococcus granulosus hypothetical protein 0.0122 0.0735 0.0714
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0151 0.1039 0.111
Giardia lamblia Kinase, PLK 0.0269 0.226 1
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.1102 0.1306
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0081 0.0312 0.035
Echinococcus granulosus dro:myosuppressin receptor 0.0467 0.4305 0.4292
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0159 0.1122 0.133
Brugia malayi STE20-like kinase MST 0.0256 0.212 0.2279
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0681 0.1162
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0251 0.207 0.2052
Entamoeba histolytica protein kinase, putative 0.0079 0.0292 0.079
Giardia lamblia Kinase, CMGC CDK 0.0116 0.0681 0.2005
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0959 0.3747
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0111 0.0621 0.0658
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis PAK box P21 Rho binding 0.0062 0.0114 0.011
Brugia malayi serine/threonine kinase 12 0.0143 0.0959 0.1024
Echinococcus multilocularis protein kinase c iota type 0.0292 0.2493 0.299
Leishmania major protein kinase, putative 0.0152 0.1044 0.4567
Echinococcus multilocularis Immunoglobulin 0.0076 0.0265 0.0294
Giardia lamblia Kinase, NEK 0.0134 0.0862 0.292
Loa Loa (eye worm) hypothetical protein 0.0076 0.0268 0.0276
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0215 0.1704 0.1829
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0277 0.2346 0.2329
Brugia malayi C1-like domain containing protein 0.0216 0.1711 0.1837
Echinococcus multilocularis casein kinase I gamma 0.009 0.0413 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0187 0.1406 0.5492
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0234 0.1892 0.1874
Loa Loa (eye worm) hypothetical protein 0.0083 0.0341 0.0355
Loa Loa (eye worm) TK/INSR protein kinase 0.0444 0.4071 0.4389
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0081 0.0316 0.1349
Onchocerca volvulus 0.0467 0.4305 0.8407
Echinococcus multilocularis serine:threonine protein kinase 0.0112 0.0633 0.0738
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0079 0.0292 0.0302
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0155 0.1076 0.1275
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0621 0.1058
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0341 0.0355
Schistosoma mansoni opsin-like receptor 0.0467 0.4305 0.7461
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0068 0.0182 0.0159
Echinococcus multilocularis dual specificity 0.012 0.0717 0.0841
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0849 0.1453
Trypanosoma cruzi casein kinase II, putative 0.0098 0.0487 0.2109
Echinococcus multilocularis neuropeptides capa receptor 0.0467 0.4305 0.5183
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0078 0.0286 0.0295
Schistosoma mansoni protein kinase 0.0225 0.1807 0.3119
Echinococcus granulosus cyclin dependent kinase 0.0116 0.0681 0.066
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0111 0.0621 0.2707
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Entamoeba histolytica protein kinase, putative 0.0069 0.0193 0.0497
Echinococcus multilocularis nervana 2 0.0125 0.0766 0.09
Brugia malayi hypothetical protein 0.0113 0.0642 0.068
Echinococcus granulosus 7TM GPCR rhodopsin 0.0467 0.4305 0.4292
Trypanosoma cruzi casein kinase, putative 0.0106 0.0576 0.2505
Brugia malayi Protein kinase domain containing protein 0.0187 0.1406 0.1507
Giardia lamblia Kinase, CMGC SRPK 0.008 0.0309 0.0121
Schistosoma mansoni serine/threonine-protein kinase 0.0162 0.1154 0.1984
Loa Loa (eye worm) CAMK protein kinase 0.0054 0.0037 0.0026
Loa Loa (eye worm) neuropeptide F receptor 0.0467 0.4305 0.4642
Brugia malayi protein kinase C3,putative 0.0156 0.1087 0.1161
Echinococcus granulosus dual specificity 0.0083 0.0339 0.0317
Loa Loa (eye worm) AGC/PKA protein kinase 0.0111 0.0621 0.0658
Brugia malayi putative neuropeptide receptor 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Entamoeba histolytica cell division protein kinase 2, putative 0.0116 0.0681 0.1929
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0143 0.0959 0.1134
Schistosoma mansoni neuropeptide receptor 0.0467 0.4305 0.7461
Brugia malayi ephrin receptor 1 precursor 0.0069 0.0192 0.0194
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0089 0.0396 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1044 0.1793
Onchocerca volvulus 0.0467 0.4305 0.8407
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0467 0.4305 0.5183
Loa Loa (eye worm) TK protein kinase 0.0128 0.0796 0.0847
Echinococcus granulosus nervana 2 0.0125 0.0766 0.0745
Leishmania major protein kinase, putative 0.0082 0.0326 0.1354
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0078 0.0286 0.0474
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0269 0.226 0.2708
Entamoeba histolytica PH domain containing protein kinase, putative 0.0162 0.1154 0.3314
Echinococcus multilocularis serine threonine protein kinase 0.0207 0.162 0.1933
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0078 0.0286 0.1214
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0959 0.1646
Brugia malayi putative serine/threonine kinase SADA gamma 0.0087 0.0375 0.0392
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0162 0.1153 0.1133
Echinococcus granulosus insulin receptor 0.0444 0.4071 0.4057
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0946 0.9258 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0081 0.0316 0.0294
Echinococcus granulosus aurora kinase A 0.0143 0.0959 0.0939
Entamoeba histolytica protein kinase, putative 0.0054 0.0036 0.0039
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0128 0.0796 0.0936
Schistosoma mansoni serine/threonine kinase 0.0215 0.1704 0.2941
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0155 0.1076 1
Echinococcus multilocularis G protein coupled receptor 139 0.0467 0.4305 0.5183
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Brugia malayi hypothetical protein 0.0068 0.0185 0.0186
Echinococcus granulosus neuropeptide receptor 0.0467 0.4305 0.4292
Echinococcus multilocularis serine:threonine protein kinase N2 0.0131 0.0828 0.0975
Echinococcus multilocularis tyrosine protein kinase Abl 0.018 0.1337 0.1591
Onchocerca volvulus 0.0294 0.2522 0.4896
Plasmodium vivax tyrosine kinase-like protein, putative 0.0078 0.0288 0.2516
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.01 0.0511 0.0865
Brugia malayi Protein kinase domain containing protein 0.0555 0.5214 0.5626
Echinococcus granulosus twitchin 0.0123 0.0749 0.0728
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0152 0.1044 0.1116
Echinococcus granulosus tyrosine kinase 0.0128 0.0796 0.0775
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Trichomonas vaginalis STE family protein kinase 0.0083 0.034 0.1327
Plasmodium falciparum casein kinase 1 0.0106 0.0576 0.5253
Plasmodium vivax glycogen synthase kinase 3, putative 0.0078 0.0286 0.2497
Brugia malayi Tyrosine-protein kinase abl-1 0.018 0.1337 0.1432
Echinococcus granulosus protein kinase c iota type 0.0292 0.2493 0.2476
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0106 0.0576 0.0609
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Schistosoma mansoni protein kinase 0.0106 0.0576 0.0978
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0182 0.0293
Schistosoma mansoni tyrosine kinase 0.0549 0.5151 0.8933
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0452 0.4146 0.4992
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0379 0.0636
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0576 0.0669
Loa Loa (eye worm) hypothetical protein 0.0113 0.0642 0.068
Entamoeba histolytica protein kinase, putative 0.0062 0.0114 0.0267
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0068 0.0185 0.0475
Brugia malayi protein kinase C II. 0.0209 0.1642 0.1762
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Schistosoma mansoni adenoreceptor 0.0467 0.4305 0.7461
Echinococcus granulosus dual specificity 0.0083 0.0339 0.0317
Onchocerca volvulus 0.0467 0.4305 0.8407
Onchocerca volvulus 0.0106 0.0576 0.1062
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Schistosoma mansoni tyrosine kinase 0.007 0.0204 0.0333
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0467 0.4305 0.7461
Schistosoma mansoni adapter molecule crk 0.0061 0.0111 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1193 0.2052
Onchocerca volvulus 0.0068 0.0185 0.0293
Echinococcus multilocularis g-protein coupled receptor 0.0467 0.4305 0.5183
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0122 0.0742 0.3216
Loa Loa (eye worm) hypothetical protein 0.0119 0.0704 0.0747
Echinococcus granulosus expressed protein 0.008 0.0309 0.0287
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0078 0.0286 0.0263
Brugia malayi Protein kinase domain containing protein 0.0112 0.0633 0.067
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.1044 0.4591
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Entamoeba histolytica protein kinase, putative 0.0291 0.2482 0.7202
Echinococcus granulosus defective proboscis extension response 0.0076 0.0265 0.0243
Onchocerca volvulus 0.0467 0.4305 0.8407
Brugia malayi Immunoglobulin I-set domain containing protein 0.0623 0.5917 0.6386
Echinococcus multilocularis neuropeptide Y receptor 0.0467 0.4305 0.5183
Echinococcus granulosus serotonin receptor 0.0467 0.4305 0.4292
Giardia lamblia Kinase, AGC PKA 0.0111 0.0621 0.17
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0256 0.212 0.2279
Brugia malayi Serotonin receptor 0.0467 0.4305 0.4642
Echinococcus granulosus biogenic amine 5HT receptor 0.0467 0.4305 0.4292
Plasmodium vivax protein kinase, putative 0.0054 0.0035 0.0113
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Giardia lamblia Aurora kinase 0.0143 0.0959 0.3413
Trichomonas vaginalis STE family protein kinase 0.0134 0.0862 0.3367
Schistosoma mansoni tyrosine kinase 0.0398 0.3596 0.6229
Echinococcus granulosus casein kinase I alpha 0.0106 0.0576 0.0554
Echinococcus granulosus g-protein coupled receptor 0.0467 0.4305 0.4292
Brugia malayi cell division control protein 2 homolog 0.0116 0.0681 0.0723
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Loa Loa (eye worm) G-protein coupled receptor 0.0467 0.4305 0.4642
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0959 0.3747
Loa Loa (eye worm) hypothetical protein 0.0061 0.0111 0.0106
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0087 0.0375 0.3347
Brugia malayi Sex muscle abnormal protein 5 0.0061 0.0111 0.0106
Entamoeba histolytica hypothetical protein 0.0383 0.3438 1
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Loa Loa (eye worm) hypothetical protein 0.0144 0.0966 0.1031
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0116 0.0681 0.0723
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0087 0.0375 0.1612
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0159 0.1122 0.133
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0643 0.251
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.012 0.0717 0.3135
Echinococcus granulosus tyrosine protein kinase HCK 0.0098 0.0488 0.0467
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Loa Loa (eye worm) hypothetical protein 0.0087 0.0372 0.0388
Brugia malayi neuropeptide F receptor 0.0467 0.4305 0.4642
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0199 0.1535 0.1647
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0263 0.2197 0.2362
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0238 0.1943 0.2325
Echinococcus multilocularis G-protein coupled receptor, putative 0.0467 0.4305 0.5183
Trypanosoma cruzi cdc2-related kinase 1 0.0116 0.0681 0.2975
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.0725
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0081 0.0316 0.1349
Loa Loa (eye worm) hypothetical protein 0.0083 0.0341 0.0355
Plasmodium falciparum serine/threonine protein kinase, putative 0.0143 0.0959 0.8897
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0467 0.4305 0.5183
Onchocerca volvulus Serine\/threonine kinase homolog 0.0269 0.226 0.4379
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0467 0.4305 0.5183
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.075 0.7229 1
Entamoeba histolytica protein kinase, putative 0.0143 0.0959 0.2743
Brugia malayi Protein kinase domain containing protein 0.0298 0.2561 0.2756
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0849 0.1453
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.2055 0.3551
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Echinococcus granulosus neuropeptides capa receptor 0.0467 0.4305 0.4292
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0115 0.0663 0.0704
Trichomonas vaginalis STE family protein kinase 0.0082 0.0326 0.1272
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0234 0.1892 0.2263
Echinococcus multilocularis g protein coupled receptor 0.0467 0.4305 0.5183
Echinococcus granulosus tyrosine protein kinase Src42A 0.0089 0.0396 0.0374
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0116 0.0681 0.2945
Onchocerca volvulus 0.0489 0.4539 0.8869
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0081 0.0316 0.1311
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0191 0.1452 0.1557
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Entamoeba histolytica casein kinase 1, putative 0.0106 0.0576 0.1619
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0053 0.0023 0.0011
Echinococcus granulosus alpha 1A adrenergic receptor 0.0467 0.4305 0.4292
Giardia lamblia Kinase, CMGC DYRK 0.0083 0.0339 0.0272
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0111 0.0621 0.2707
Echinococcus multilocularis casein kinase i 0.0106 0.0576 0.0669
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0068 0.0185 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.1452 0.2502
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0184 0.1379 0.136
Loa Loa (eye worm) AUR protein kinase 0.0143 0.0959 0.1024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0134 0.0862 0.3413
Entamoeba histolytica casein kinase, putative 0.0106 0.0576 0.1619
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis cyclin dependent kinase 0.0116 0.0681 0.0797
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0143 0.0959 0.2743
Loa Loa (eye worm) hypothetical protein 0.0234 0.1894 0.2035
Onchocerca volvulus 0.014 0.0923 0.1747
Echinococcus granulosus casein kinase i 0.0106 0.0576 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.1535 0.2647
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0111 0.0621 0.2434
Schistosoma mansoni titin 0.0054 0.0037 0.0041
Brugia malayi ORL1-like opioid receptor 0.0467 0.4305 0.4642
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.06
Schistosoma mansoni growth hormone secretagogue receptor 0.0467 0.4305 0.7461
Giardia lamblia Kinase, CMGC CDK 0.0116 0.0681 0.2005
Leishmania major casein kinase II, putative 0.0098 0.0487 0.2074
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0079 0.0292 0.0327
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0467 0.4305 0.7461
Onchocerca volvulus Tyrosine kinase homolog 0.0545 0.5113 1
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0201 0.1555 0.1668
Loa Loa (eye worm) CDC7 protein kinase 0.0087 0.0379 0.0396
Echinococcus granulosus neuropeptide s receptor 0.0467 0.4305 0.4292
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0467 0.4305 0.4642
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0111 0.0621 0.2358
Brugia malayi Protein kinase domain containing protein 0.0601 0.5695 0.6146
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.0187 0.0775
Echinococcus multilocularis rho associated protein kinase 0.0324 0.2831 0.34
Entamoeba histolytica protein kinase, putative 0.0069 0.0193 0.0497
Echinococcus multilocularis casein kinase I delta 0.0106 0.0576 0.0669
Echinococcus granulosus rho-associated protein kinase 1 0.0324 0.2831 0.2815
Loa Loa (eye worm) hypothetical protein 0.0053 0.0023 0.0011
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0082 0.0326 0.1193
Echinococcus multilocularis sex peptide receptor 0.0467 0.4305 0.5183
Echinococcus granulosus peptide allatostatin:somatostatin 0.0467 0.4305 0.4292
Entamoeba histolytica protein kinase, putative 0.0166 0.1193 0.3428
Loa Loa (eye worm) hypothetical protein 0.0194 0.148 0.1587
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Giardia lamblia Kinase, AGC PKA 0.0155 0.1076 0.4001
Onchocerca volvulus 0.0467 0.4305 0.8407
Echinococcus granulosus tyrosine protein kinase Lyn 0.0189 0.1431 0.1412
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0111 0.0621 0.2707
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0159 0.1122 0.133
Leishmania major protein kinase A catalytic subunit isoform 2 0.0111 0.0621 0.2675
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1642 0.2833
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Brugia malayi hypothetical protein 0.0083 0.0341 0.0355
Schistosoma mansoni protein kinase 0.0083 0.034 0.0568
Echinococcus multilocularis Immunoglobulin 0.0076 0.0265 0.0294
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0467 0.4305 0.4292
Toxoplasma gondii AGC kinase 0.0111 0.0621 0.2434
Echinococcus granulosus raf serine:threonine protein kinase 0.0081 0.0313 0.0291
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0058 0.0079 0.0308
Schistosoma mansoni rap gtpase-activating protein 0.0113 0.0642 0.1093
Schistosoma mansoni hypothetical protein 0.0467 0.4305 0.7461
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0113 0.0642 0.062
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0076 0.0265 0.0294
Echinococcus multilocularis epidermal growth factor receptor 0.0608 0.5765 0.6951
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0309 0.0515
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Giardia lamblia Kinase, STE STE20 0.0083 0.034 0.0274
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0078 0.0288 0.2516
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.207 0.3576
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0078 0.0286 0.0295
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0125 0.0766 0.09
Schistosoma mansoni ephrin receptor 0.0103 0.0545 0.0924
Brugia malayi map kinase activated protein kinase protein 2 0.0394 0.3551 0.3827
Schistosoma mansoni tyrosine kinase 0.0248 0.2039 0.3522
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1892 0.3267
Schistosoma mansoni protein kinase 0.0264 0.2204 0.3809
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0234 0.1901 0.1882
Trypanosoma cruzi cdc2-related kinase 3 0.0116 0.0681 0.2975
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.1102 0.1306
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0681 0.2661
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Toxoplasma gondii histone kinase SNF1, putative 0.0087 0.0375 0.1433
Schistosoma mansoni protein kinase 0.0225 0.1807 0.3119
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0467 0.4305 0.7461
Echinococcus granulosus ephrin type A receptor 4 A 0.0103 0.0545 0.0523
Plasmodium vivax protein kinase Crk2 0.0116 0.0681 0.6257
Echinococcus granulosus tyrosine protein kinase Blk 0.0128 0.0796 0.0775
Brugia malayi Immunoglobulin I-set domain containing protein 0.0255 0.2118 0.2276
Trypanosoma brucei aurora B kinase 0.0143 0.0959 0.3691
Loa Loa (eye worm) hypothetical protein 0.0053 0.003 0.0019
Onchocerca volvulus 0.0068 0.0185 0.0293
Loa Loa (eye worm) hypothetical protein 0.0076 0.0265 0.0273
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0621 0.1058
Entamoeba histolytica serine/threonine protein kinase, putative 0.0087 0.0375 0.1032
Schistosoma mansoni protein kinase 0.0083 0.034 0.0568
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0467 0.4305 0.5183
Echinococcus granulosus tyrosine protein kinase Fyn 0.0159 0.1122 0.1102
Schistosoma mansoni hypothetical protein 0.0467 0.4305 0.7461
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0234 0.1894 0.1876
Schistosoma mansoni tyrosine kinase 0.0159 0.1122 0.1928
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.2544 0.4401
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0087 0.0375 0.0427
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Entamoeba histolytica protein kinase, putative 0.0298 0.2561 0.7432
Echinococcus granulosus tm gpcr rhodopsin 0.0467 0.4305 0.4292
Brugia malayi G protein-coupled receptor F59B2.13 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0221 0.1759 0.1888
Brugia malayi hypothetical protein 0.0221 0.1759 0.1888
Schistosoma mansoni biogenic amine (5HT) receptor 0.0467 0.4305 0.7461
Echinococcus multilocularis serine:threonine protein kinase 3 0.0256 0.212 0.2538
Trypanosoma brucei protein kinase, putative 0.0081 0.0316 0.1156
Giardia lamblia Kinase, CK1 Casein kinase 0.0106 0.0576 0.147
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0166 0.1193 0.1417
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0379 0.1479
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0118
Echinococcus multilocularis mitogen activated protein kinase 0.0081 0.0316 0.0355
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0159 0.1122 0.1102
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus casein kinase I alpha 0.0106 0.0576 0.0554
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Onchocerca volvulus 0.0113 0.0642 0.1192
Leishmania major protein kinase, putative 0.0069 0.0187 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Echinococcus granulosus dual specificity 0.0083 0.0339 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Echinococcus multilocularis neuropeptides capa receptor 0.0467 0.4305 0.5183
Brugia malayi protein-tyrosine kinase 0.0128 0.0796 0.0847
Brugia malayi phosphoinositide-dependent protein kinase I 0.0079 0.0292 0.0302
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0083 0.034 0.0384
Echinococcus granulosus tyrosine protein kinase Fyn 0.0159 0.1122 0.1102
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0379 0.1479
Echinococcus multilocularis serotonin receptor 0.0467 0.4305 0.5183
Loa Loa (eye worm) TK/ROR protein kinase 0.0056 0.0052 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0292 0.1142
Brugia malayi Protein kinase domain containing protein 0.0191 0.1452 0.1557
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0082 0.0326 0.0887
Brugia malayi Protein kinase domain containing protein 0.0366 0.3265 0.3518
Brugia malayi Protein kinase domain 0.0083 0.034 0.0354
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0467 0.4305 0.4642
Echinococcus granulosus c src tyrosine kinase 0.01 0.0511 0.0489
Schistosoma mansoni neuropeptide receptor 0.0467 0.4305 0.7461
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0083 0.034 0.0318
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0292 0.1142
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi Tachykinin-like peptides receptor 99D 0.0467 0.4305 0.4642
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0143 0.0959 0.8897
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0316 0.1234
Echinococcus multilocularis dual specificity 0.0083 0.0339 0.0383
Onchocerca volvulus 0.0087 0.0379 0.0674
Echinococcus granulosus cyclin dependent kinase 5 0.0116 0.0681 0.066
Onchocerca volvulus 0.0467 0.4305 0.8407
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0073 0.0227 0.0232
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.008 0.0309 0.0321
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0174 0.1275 0.1365
Loa Loa (eye worm) AGC/PKN protein kinase 0.0297 0.2544 0.2738
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0083 0.034 0.0384
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0083 0.0339 0.1247
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0069 0.0187 0.0668
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0068 0.0182 0.0192
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi Protein kinase domain containing protein 0.0449 0.4117 0.4439
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0238 0.1943 0.1925
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0681 0.1162
Brugia malayi SH2 domain containing protein 0.0068 0.0185 0.0186
Onchocerca volvulus 0.0068 0.0185 0.0293
Plasmodium falciparum serine/threonine protein kinase KIN 0.0087 0.0375 0.3347
Onchocerca volvulus 0.0068 0.0185 0.0293
Onchocerca volvulus 0.0087 0.0379 0.0674
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0081 0.0316 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0316 0.0527
Schistosoma mansoni tyrosine kinase 0.01 0.0511 0.0865
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.2055 0.3551
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Entamoeba histolytica casein kinase, putative 0.0098 0.0487 0.1359
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.0725
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0149 0.1015 0.1084
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0467 0.4305 0.7461
Schistosoma mansoni biogenic amine receptor 0.0467 0.4305 0.7461
Entamoeba histolytica protein kinase, putative 0.0098 0.0488 0.1364
Echinococcus granulosus casein kinase I delta 0.0106 0.0576 0.0554
Leishmania major casein kinase, putative 0.0106 0.0576 0.2472
Schistosoma mansoni vav2 0.008 0.03 0.0498
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis tyrosine protein kinase Blk 0.0128 0.0796 0.0936
Schistosoma mansoni hypothetical protein 0.0103 0.0539 0.0915
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0286 0.077
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.2101 0.363
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0184 0.1379 0.1642
Echinococcus granulosus somatostatin receptor 0.0467 0.4305 0.4292
Brugia malayi Serine/threonine-protein kinase SULU 0.0221 0.1759 0.1888
Echinococcus multilocularis serine:threonine protein kinase 38 0.0166 0.1193 0.1417
Echinococcus multilocularis expressed protein 0.008 0.0309 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0313 0.0522
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0959 0.2743
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0053 0.0023 0.0011
Giardia lamblia Kinase, CAMK CAMKL 0.0087 0.0375 0.0453
Entamoeba histolytica p21-activated kinase 0.0091 0.0419 0.1159
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0221 0.1759 0.174
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0068 0.0185 0.0186
Schistosoma mansoni tyrosine kinase 0.036 0.3196 0.5533
Schistosoma mansoni neuropeptide f receptor 76f 0.0467 0.4305 0.7461
Brugia malayi Dopamine receptor protein 1 0.0467 0.4305 0.4642
Schistosoma mansoni myosin xvIII 0.0467 0.4305 0.7461
Echinococcus granulosus calcium activated potassium channel 0.0133 0.0849 0.0828
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0292 0.1142
Brugia malayi RhoGAP domain containing protein 0.0072 0.0221 0.0225
Schistosoma mansoni tyrosine kinase 0.0159 0.1122 0.1928
Schistosoma mansoni hypothetical protein 0.0113 0.0642 0.1093
Echinococcus granulosus Vam6:Vps39 protein 0.0113 0.0642 0.062
Echinococcus granulosus NCK adaptor protein 0.0061 0.0111 0.0088
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0143 0.0959 0.2743
Onchocerca volvulus 0.0063 0.0134 0.0191
Loa Loa (eye worm) hypothetical protein 0.0122 0.0735 0.0781
Schistosoma mansoni serine/threonine-protein kinase 0.0162 0.1154 0.1984
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Echinococcus multilocularis epidermal growth factor receptor 0.0398 0.3596 0.4326
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0023 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Echinococcus multilocularis activin receptor type 0.0069 0.0187 0.0199
Schistosoma mansoni neuropeptide F-like receptor 0.0467 0.4305 0.7461
Giardia lamblia Kinase, NEK 0.0134 0.0862 0.292
Entamoeba histolytica protein kinase, putative 0.0298 0.2561 0.7432
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0095 0.0456 0.0479
Echinococcus granulosus serine/threonine protein kinase 0.0162 0.1154 0.1134
Brugia malayi putative neuropeptide receptor NPR1 0.0467 0.4305 0.4642
Echinococcus granulosus neuropeptide Y receptor 0.0467 0.4305 0.4292
Echinococcus multilocularis titin 0.0054 0.0037 0.0017
Toxoplasma gondii CMGC kinase, CK2 family 0.0098 0.0487 0.1887
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0375 0.063
Echinococcus multilocularis growth factor receptor bound protein 2 0.0061 0.0111 0.0106
Loa Loa (eye worm) G-protein coupled receptor 0.0467 0.4305 0.4642
Trypanosoma brucei protein kinase, putative 0.0078 0.0286 0.1036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0061 0.0111 0.0106
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi Melatonin receptor type 1A 0.0467 0.4305 0.4642
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0467 0.4305 0.7461
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0162 0.1153 0.1369
Brugia malayi Furin-like cysteine rich region family protein 0.0608 0.5765 0.6221
Loa Loa (eye worm) hypothetical protein 0.021 0.1646 0.1767
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0231 0.1862 0.2
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0467 0.4305 0.4642
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0449 0.4117 0.4439
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.014 0.0923 0.0985
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0076 0.0266 0.1127
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0951 0.0931
Entamoeba histolytica protein kinase domain containing protein 0.0083 0.0339 0.0927
Echinococcus granulosus serine:threonine protein kinase 0.0112 0.0633 0.0611
Loa Loa (eye worm) hypothetical protein 0.0087 0.0375 0.0392
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0467 0.4305 0.5183
Onchocerca volvulus Serine\/threonine kinase homolog 0.0162 0.1153 0.22
Echinococcus granulosus protein tyrosine kinase 0.0549 0.5151 0.514
Echinococcus multilocularis dro:myosuppressin receptor 0.0467 0.4305 0.5183
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0159 0.1122 0.133
Entamoeba histolytica protein kinase 2, putative 0.0155 0.1076 0.3083
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0057 0.0065 0.0057
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0081 0.0316 0.1349
Onchocerca volvulus 0.0467 0.4305 0.8407
Plasmodium falciparum glycogen synthase kinase 3 0.0078 0.0286 0.2497
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0467 0.4305 0.4292
Echinococcus granulosus serine threonine protein kinase nrc 0.0155 0.1076 0.1055
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0849 0.1453
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis dual specificity 0.0083 0.0339 0.0383
Schistosoma mansoni alpha-1 adrenergic receptor 0.0467 0.4305 0.7461
Leishmania major protein kinase A catalytic subunit isoform 1 0.0111 0.0621 0.2675
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0216 0.1711 0.1837
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0394 0.3551 0.4271
Echinococcus granulosus cGMP dependent protein kinase 0.0132 0.0846 0.0825
Brugia malayi Protein kinase domain containing protein 0.0059 0.0088 0.0081
Giardia lamblia Kinase, CAMK CAMKL 0.0087 0.0375 0.0453
Entamoeba histolytica protein kinase domain containing protein 0.0201 0.1555 0.4487
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1555 0.2681
Echinococcus granulosus mitogen activated protein kinase 0.0081 0.0316 0.0294
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0082 0.0326 0.0887
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0467 0.4305 0.7461
Loa Loa (eye worm) hypothetical protein 0.0083 0.0341 0.0355
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.1044 0.4591
Plasmodium falciparum protein serine/threonine kinase-1 0.0152 0.1044 0.9704
Toxoplasma gondii AGC kinase 0.0291 0.2482 1
Giardia lamblia Kinase, CMGC CLK 0.0152 0.1044 0.3844
Brugia malayi Doublecortin family protein 0.0149 0.1015 0.1084
Brugia malayi Hr1 repeat family protein 0.0297 0.2544 0.2738
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0184 0.1379 0.1478
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1193 0.2052
Echinococcus multilocularis 0.0122 0.0735 0.0862
Schistosoma mansoni protein kinase 0.0098 0.0487 0.0824
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0366 0.3265 0.3925
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0291 0.2482 0.2671
Echinococcus granulosus casein kinase ii subunit alpha 0.0098 0.0487 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.0215 0.1704 0.6656
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0187 0.1406 0.1507
Loa Loa (eye worm) hypothetical protein 0.0112 0.0633 0.067
Schistosoma mansoni ste20-related kinase 0.0203 0.1581 0.2726
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0152 0.1044 0.4025
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0467 0.4305 0.7461
Loa Loa (eye worm) hypothetical protein 0.0113 0.0642 0.068
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Echinococcus multilocularis dual specificity 0.0083 0.0339 0.0383
Loa Loa (eye worm) neuropeptide F receptor 0.0467 0.4305 0.4642
Loa Loa (eye worm) hypothetical protein 0.0145 0.0973 0.1039
Trichomonas vaginalis AGC family protein kinase 0.0134 0.0862 0.3367
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0155 0.1076 0.1055
Toxoplasma gondii aurora kinase 0.0143 0.0959 0.3809
Echinococcus granulosus mitogen activated protein kinase 11 0.0157 0.1102 0.1081
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0601 0.5695 0.6146
Brugia malayi Kinase associated domain 1 family protein 0.0103 0.0539 0.0569
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.076 0.2969
Giardia lamblia Kinase, CMGC CK2 0.0098 0.0487 0.1019
Trypanosoma brucei polo-like protein kinase 0.0269 0.226 0.8814
Echinococcus multilocularis neuropeptide receptor 0.0467 0.4305 0.5183
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0159 0.1122 0.133
Trichomonas vaginalis AGC family protein kinase 0.0187 0.1406 0.5492
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0633 0.247
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0467 0.4305 0.5183
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0959 0.3747
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0078 0.0286 0.1175
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0292 0.0486
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus granulosus allatostatin A receptor 0.0467 0.4305 0.4292
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0081 0.0316 0.1311
Loa Loa (eye worm) hypothetical protein 0.014 0.0923 0.0985
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0201 0.1555 0.1536
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0128 0.0796 0.0775
Trypanosoma cruzi casein kinase, putative 0.0106 0.0576 0.2505
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Schistosoma mansoni amine GPCR 0.0467 0.4305 0.7461
Echinococcus granulosus Protein kinase C brain isozyme 0.0249 0.2055 0.2037
Trypanosoma cruzi casein kinase, putative 0.0106 0.0576 0.2505
Loa Loa (eye worm) hypothetical protein 0.0082 0.0326 0.0339
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0081 0.0316 0.1349
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Echinococcus granulosus growth factor receptor bound protein 2 0.0061 0.0111 0.0088
Trichomonas vaginalis STE family protein kinase 0.0062 0.0114 0.0444
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.3551 0.6151
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0576 0.0669
Schistosoma mansoni protein kinase C mu 0.0216 0.1711 0.2952
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0681 0.2661
Loa Loa (eye worm) hypothetical protein 0.0112 0.063 0.0668
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.0725
Echinococcus granulosus casein kinase I delta 0.0106 0.0576 0.0554
Echinococcus multilocularis death associated protein kinase 1 0.0852 0.8283 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0106 0.0576 0.0609
Echinococcus granulosus g protein coupled receptor 0.0467 0.4305 0.4292
Brugia malayi Tyrosine-protein kinase abl-1 0.0129 0.0812 0.0865
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0467 0.4305 0.4292
Loa Loa (eye worm) hypothetical protein 0.0112 0.063 0.0668
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis serine:threonine protein kinase 0.0112 0.0633 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.1379 0.2376
Trichomonas vaginalis AGC family protein kinase 0.0298 0.2561 1
Schistosoma mansoni neuropeptide receptor 0.0467 0.4305 0.7461
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0467 0.4305 0.4642
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0159 0.1122 0.133
Schistosoma mansoni serine/threonine kinase 0.0166 0.1193 0.2052
Trichomonas vaginalis STE family protein kinase 0.0083 0.034 0.1327
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi serine/threonine protein kinase 6 0.0143 0.0959 0.1024
Echinococcus granulosus cyclin dependent kinase 1 0.0116 0.0681 0.066
Loa Loa (eye worm) hypothetical protein 0.0144 0.0966 0.1031
Echinococcus granulosus NDR protein kinase 0.0166 0.1193 0.1173
Loa Loa (eye worm) hypothetical protein 0.0182 0.1359 0.1456
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0125 0.0766 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.1694 0.2923
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0083 0.0339 0.1453
Onchocerca volvulus 0.0467 0.4305 0.8407
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.2197 0.3797
Brugia malayi serine/threonine-protein kinase PAK 7 0.0231 0.1862 0.2
Echinococcus multilocularis 0.0175 0.1287 0.153
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0467 0.4305 0.4642
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0159 0.1122 0.133
Schistosoma mansoni tyrosine kinase 0.01 0.0511 0.0865
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Brugia malayi Protein kinase domain containing protein 0.0191 0.1453 0.1557
Echinococcus granulosus tachykinin peptides receptor 99D 0.0467 0.4305 0.4292
Echinococcus granulosus orexin receptor type 2 0.0467 0.4305 0.4292
Echinococcus multilocularis cyclin dependent kinase 5 0.0116 0.0681 0.0797
Brugia malayi intracellular kinase 0.0078 0.0286 0.0295
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0191 0.1453 0.1557
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0576 0.2248
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0037 0.0041
Trypanosoma cruzi cdc2-related kinase 1 0.0116 0.0681 0.2975
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Echinococcus granulosus tyrosine protein kinase shark 0.0068 0.0185 0.0163
Plasmodium vivax casein kinase 1, putative 0.0106 0.0576 0.5253
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0111 0.0621 0.5685
Schistosoma mansoni kinase 0.0288 0.2452 0.424
Brugia malayi follicle stimulating hormone receptor 0.0467 0.4305 0.4642
Echinococcus granulosus dual specificity protein kinase clk2 0.0152 0.1044 0.1024
Schistosoma mansoni amine GPCR 0.0467 0.4305 0.7461
Schistosoma mansoni hypothetical protein 0.0467 0.4305 0.7461
Schistosoma mansoni tyrosine kinase 0.0203 0.1575 0.2716
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0467 0.4305 0.4292
Echinococcus multilocularis g protein coupled receptor 0.0467 0.4305 0.5183
Toxoplasma gondii casein kinase I 0.0106 0.0576 0.2249
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0225 0.1807 0.216
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Schistosoma mansoni cell adhesion molecule 0.0102 0.0531 0.0901
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.226 0.8824
Echinococcus multilocularis serine:threonine protein kinase N2 0.0297 0.2544 0.3053
Entamoeba histolytica SH2-protein kinase domain containing protein 0.006 0.0095 0.021
Plasmodium falciparum protein kinase 5 0.0116 0.0681 0.6257
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0375 0.063
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0316 0.1234
Echinococcus granulosus protein kinase C gamma type 0.0207 0.162 0.1601
Entamoeba histolytica PH domain containing protein kinase, putative 0.0162 0.1154 0.3314
Brugia malayi Protein kinase domain containing protein 0.0162 0.1153 0.1233
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0487 0.1359
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.4305 0.4292
Loa Loa (eye worm) hypothetical protein 0.0111 0.0621 0.0658
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Echinococcus multilocularis neuroglian 0.0093 0.044 0.0505
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0056 0.0052 0.0029
Entamoeba histolytica protein kinase , putative 0.0143 0.0959 0.2743
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0159 0.1122 0.133
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus granulosus cGMP dependent protein kinase 1 0.0132 0.0846 0.0825
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Brugia malayi Protein kinase domain containing protein 0.0116 0.0681 0.0723
Toxoplasma gondii AGC kinase 0.0111 0.0621 0.2434
Echinococcus multilocularis c src tyrosine kinase 0.01 0.0511 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0339 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Schistosoma mansoni tyrosine kinase 0.0074 0.0242 0.0399
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0269 0.226 0.243
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0199 0.1535 0.1831
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0083 0.034 0.0318
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.008 0.0309 0.113
Echinococcus multilocularis tyrosine protein kinase Srms 0.0128 0.0796 0.0936
Onchocerca volvulus 0.0467 0.4305 0.8407
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0366 0.3265 0.3518
Echinococcus multilocularis neuropeptide Y receptor 0.0467 0.4305 0.5183
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0079 0.0308
Echinococcus granulosus fibroblast growth factor receptor 4 0.0238 0.1943 0.1925
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.06
Leishmania major protein kinase, putative 0.0152 0.1044 0.4567
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0087 0.0375 0.1575
Loa Loa (eye worm) TK/ABL protein kinase 0.0277 0.2346 0.2524
Schistosoma mansoni opsin-like receptor 0.0467 0.4305 0.7461
Echinococcus granulosus epidermal growth factor receptor 0.0398 0.3596 0.3581
Trypanosoma cruzi polo-like protein kinase, putative 0.0269 0.226 1
Onchocerca volvulus 0.0467 0.4305 0.8407
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0157 0.1097 0.4283
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0113 0.0642 0.0749
Onchocerca volvulus 0.0467 0.4305 0.8407
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0083 0.0339 0.0353
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0316 0.1234
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0053 0.0023 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0118 0.07 0.1983
Echinococcus multilocularis hypothetical protein 0.0103 0.0539 0.0625
Echinococcus multilocularis neuropeptide FF receptor 2 0.0467 0.4305 0.5183
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0467 0.4305 0.7461
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.076 0.2969
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0467 0.4305 0.4642
Schistosoma mansoni amine GPCR 0.0467 0.4305 0.7461
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0286 0.1115
Brugia malayi Serotonin receptor 0.0467 0.4305 0.4642
Schistosoma mansoni biogenic amine receptor 0.0467 0.4305 0.7461
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Brugia malayi Fibronectin type III domain containing protein 0.0083 0.0341 0.0355
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0467 0.4305 0.5183
Echinococcus multilocularis fmrfamide receptor 0.0467 0.4305 0.5183
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1759 0.3035
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Echinococcus granulosus tm gpcr rhodopsin 0.0467 0.4305 0.4292
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0717 0.2034
Onchocerca volvulus 0.0467 0.4305 0.8407
Entamoeba histolytica protein kinase, putative 0.0083 0.0339 0.0927
Entamoeba histolytica hypothetical protein 0.012 0.0717 0.2034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0467 0.4305 0.7461
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0576 0.2248
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0339 0.1325
Onchocerca volvulus 0.0186 0.1401 0.2689
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0467 0.4305 0.4642
Brugia malayi Protein kinase domain containing protein 0.0601 0.5695 0.6146
Onchocerca volvulus 0.0144 0.0966 0.183
Echinococcus granulosus serine:threonine protein kinase N2 0.0297 0.2544 0.2527
Loa Loa (eye worm) hypothetical protein 0.009 0.0408 0.0427
Entamoeba histolytica protein kinase, putative 0.0068 0.0182 0.0466
Echinococcus multilocularis allatostatin A receptor 0.0467 0.4305 0.5183
Giardia lamblia Kinase, CDC7 0.0087 0.0379 0.0472
Brugia malayi Protein kinase domain containing protein 0.0946 0.9258 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0098 0.0488 0.0564
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0098 0.0487 0.4407
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.012 0.0717 0.3105
Plasmodium falciparum cGMP-dependent protein kinase 0.0132 0.0846 0.782
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0467 0.4305 0.5183
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0238 0.1943 0.2325
Entamoeba histolytica cell division protein kinase 2, putative 0.0116 0.0681 0.1929
Echinococcus granulosus biogenic amine 5HT receptor 0.0467 0.4305 0.4292
Echinococcus multilocularis orexin receptor type 2 0.0467 0.4305 0.5183
Echinococcus multilocularis tyrosine kinase 0.0068 0.0185 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0846 0.1448
Echinococcus granulosus rhodopsin orphan GPCR 0.0467 0.4305 0.4292
Brugia malayi Protein kinase domain containing protein 0.0068 0.0185 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.1153 0.1983
Schistosoma mansoni protein kinase 0.0143 0.0959 0.1646
Brugia malayi Protein kinase domain containing protein 0.012 0.0717 0.0762
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0072 0.0221 0.0225
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0056 0.0052 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus multilocularis serotonin receptor 0.0467 0.4305 0.5183
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0111 0.0621 0.0725
Echinococcus granulosus serine:threonine kinase SAD 1 0.0087 0.0375 0.0353
Brugia malayi P38 map kinase family protein 2 0.0157 0.1102 0.1177
Brugia malayi Protein kinase domain containing protein 0.0192 0.1462 0.1568
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0467 0.4305 0.4642
Echinococcus granulosus CDC7 cell division cycle 7 0.0087 0.0379 0.0357
Onchocerca volvulus 0.0078 0.0286 0.0491
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0467 0.4305 0.5183
Brugia malayi probable protein kinase 0.0264 0.2204 0.2369
Brugia malayi Protein kinase domain containing protein 0.008 0.0309 0.0321
Echinococcus multilocularis insulin receptor 0.0444 0.4071 0.4901
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0162 0.1153 0.1233
Echinococcus multilocularis casein kinase ii subunit alpha 0.0098 0.0487 0.0562
Schistosoma mansoni hypothetical protein 0.0103 0.0539 0.0915
Echinococcus multilocularis g protein coupled receptor 0.0467 0.4305 0.5183
Giardia lamblia Kinase, STE STE20 0.0082 0.0326 0.0203
Echinococcus granulosus c-Jun N-terminal kinases 0.0263 0.2197 0.2179
Loa Loa (eye worm) hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis NCK adaptor protein 0.0061 0.0111 0.0106
Echinococcus granulosus hypothetical protein 0.0467 0.4305 0.4292
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.1102 0.1306
Schistosoma mansoni protein kinase 0.0053 0.0023 0.0017
Brugia malayi Protein kinase domain containing protein 0.0444 0.4071 0.4389
Brugia malayi Protein kinase domain containing protein 0.0068 0.0185 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0375 0.1465
Brugia malayi Protein kinase domain containing protein 0.0183 0.1373 0.1472
Schistosoma mansoni hypothetical protein 0.0467 0.4305 0.7461
Echinococcus granulosus titin 0.0054 0.0037 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0576 0.0978
Loa Loa (eye worm) hypothetical protein 0.0186 0.1401 0.1502
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0098 0.0487 0.0512
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0467 0.4305 0.5183
Brugia malayi SRC-1 0.0159 0.1122 0.1199
Brugia malayi hypothetical protein 0.0467 0.4305 0.4642
Echinococcus multilocularis cyclin dependent kinase 1 0.0116 0.0681 0.0797
Echinococcus granulosus serine:threonine protein kinase N2 0.0131 0.0828 0.0808
Trypanosoma cruzi casein kinase, putative 0.0106 0.0576 0.2505
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0487 0.19
Loa Loa (eye worm) AGC/AKT protein kinase 0.0298 0.2561 0.2756
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0467 0.4305 0.5183
Loa Loa (eye worm) hypothetical protein 0.0065 0.0144 0.0142
Brugia malayi p70 ribosomal S6 kinase beta 0.0291 0.2482 0.2671
Echinococcus multilocularis rhodopsin orphan GPCR 0.0467 0.4305 0.5183
Echinococcus granulosus G protein coupled receptor 139 0.0467 0.4305 0.4292
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0143 0.0959 0.0939
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0083 0.0339 0.1287
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0132 0.0846 0.3348
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0234 0.1901 0.2273
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0623 0.5917 0.6386
Trypanosoma cruzi cdc2-related kinase 3 0.0116 0.0681 0.2975
Echinococcus granulosus tyrosine protein kinase Srms 0.0068 0.0185 0.0163
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0078 0.0286 0.0318
Loa Loa (eye worm) AGC/NDR protein kinase 0.0166 0.1193 0.1277
Schistosoma mansoni amine GPCR 0.0467 0.4305 0.7461
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0185 0.0186
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0269 0.226 0.2242
Schistosoma mansoni tyrosine kinase 0.0444 0.4071 0.7055
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0467 0.4305 0.7461
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0143 0.0959 0.2743
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0951 0.1124
Echinococcus multilocularis protein kinase c epsilon type 0.0209 0.1642 0.1961
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0152 0.1044 0.4025
Brugia malayi G-protein coupled receptor 0.0467 0.4305 0.4642
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0134 0.0862 0.7973
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0225 0.1807 0.1789
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0155 0.1076 0.4729

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 23 uM Inhibitory activity towards human butrylcholinesterase ChEMBL. 15139762
IC50 (binding) > 50 uM Inhibitory activity towards Electrophorus electricus acetylcholinesterase ChEMBL. 15139762

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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