Detailed information for compound 940269

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 489.376 | Formula: C22H23Cl2FN8
  • H donors: 4 H acceptors: 0 LogP: 3.39 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc2c1c(/C=N/NC1=NCCN1)c1c(c2/C=N/NC2=NCCN2)cccc1.Cl.Cl
  • InChi: 1S/C22H21FN8.2ClH/c23-19-7-3-6-16-17(12-28-30-21-24-8-9-25-21)14-4-1-2-5-15(14)18(20(16)19)13-29-31-22-26-10-11-27-22;;/h1-7,12-13H,8-11H2,(H2,24,25,30)(H2,26,27,31);2*1H/b28-12+,29-13+;;
  • InChiKey: ZLBBPHPAPONVJZ-IVJWAPCLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Schistosoma mansoni titin 0.0076 0.0142 0.021
Schistosoma mansoni protein kinase 0.0093 0.0301 0.0515
Loa Loa (eye worm) AGC/AKT protein kinase 0.0324 0.2485 0.2757
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Giardia lamblia Aurora kinase 0.0157 0.0907 0.3847
Echinococcus granulosus tyrosine kinase 0.0261 0.1891 0.1866
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Entamoeba histolytica protein kinase domain containing protein 0.0218 0.1488 0.4381
Echinococcus granulosus hypothetical protein 0.0093 0.0309 0.0278
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0532 0.1944
Schistosoma mansoni protein tyrosine kinase 0.0073 0.0113 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Brugia malayi Furin-like cysteine rich region family protein 0.052 0.4346 0.4822
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0096 0.0336 0.0379
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0216 0.1469 0.163
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0255 0.0803
Echinococcus multilocularis carbonic anhydrase II 0.0226 0.1563 0.1908
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0089 0.0272 0.0698
Schistosoma mansoni Neurotrimin precursor (hNT) 0.009 0.0275 0.0464
Brugia malayi TAR-binding protein 0.0064 0.0032 0.0035
Echinococcus multilocularis casein kinase I delta 0.0117 0.0532 0.0623
Schistosoma mansoni SH2A 0.0093 0.0309 0.053
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0177 0.1096 0.1216
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0136 0.0708 0.2563
Brugia malayi bone morphogenetic protein type 1 receptor 0.0073 0.0113 0.0125
Loa Loa (eye worm) protein kinase domain-containing protein 0.023 0.1596 0.1771
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0576 0.1041
Loa Loa (eye worm) TK/DDR protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0122 0.0583 0.0647
Giardia lamblia Kinase, NEK 0.0147 0.0812 0.3386
Onchocerca volvulus 0.0073 0.0113 0.0068
Schistosoma mansoni serine/threonine RGC 0.0073 0.0113 0.0154
Loa Loa (eye worm) hypothetical protein 0.0096 0.0336 0.0373
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0203 0.1343 0.149
Echinococcus multilocularis heat shock protein 70 0.0073 0.0113 0.0101
Echinococcus multilocularis serine:threonine protein kinase N2 0.0181 0.1135 0.1374
Trypanosoma cruzi casein kinase, putative 0.0117 0.0532 0.1804
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.067 0.1834
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0735 0.2784
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0532 0.1944
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Brugia malayi hypothetical protein 0.012 0.0563 0.0625
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0286 0.213 0.2614
Brugia malayi serine/threonine-protein kinase plk-2 0.0291 0.2177 0.2415
Echinococcus multilocularis serine:threonine protein kinase 38 0.0181 0.1135 0.1374
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0635 0.1153
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Echinococcus granulosus tyrosine protein kinase Src42A 0.0305 0.231 0.2285
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Schistosoma mansoni protein kinase 0.0395 0.3159 0.5976
Schistosoma mansoni tyrosine protein kinase 0.0073 0.0113 0.0154
Echinococcus granulosus calcium dependent protein kinase 0.0073 0.0116 0.0085
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0128 0.0635 0.2291
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0319 0.2437 1
Schistosoma mansoni protein kinase 0.0108 0.0448 0.0796
Brugia malayi Protein kinase domain containing protein 0.0209 0.1398 0.1551
Brugia malayi Fes/CIP4 homology domain containing protein 0.0126 0.0616 0.0684
Brugia malayi Serine/threonine-protein kinase SULU 0.0239 0.1687 0.1872
Brugia malayi Protein kinase domain containing protein 0.0646 0.5533 0.6139
Entamoeba histolytica protein kinase, putative 0.0314 0.2394 0.7199
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0109 0.0452 0.0422
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0181 0.1135 0.1374
Loa Loa (eye worm) SRC-1 0.0305 0.231 0.2563
Brugia malayi casein kinase 1, delta 0.0117 0.0532 0.059
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Brugia malayi Protein kinase domain containing protein 0.0646 0.5533 0.6139
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0165 0.099 0.3697
Brugia malayi Protein kinase domain containing protein 0.0128 0.0635 0.0705
Giardia lamblia Kinase, AGC AKT 0.0126 0.0617 0.2446
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.1135 0.2109
Loa Loa (eye worm) hypothetical protein 0.0109 0.0452 0.0502
Echinococcus multilocularis tyrosine protein kinase csk 0.0073 0.0113 0.0101
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Plasmodium vivax protein kinase Crk2 0.0128 0.0635 0.5758
Echinococcus multilocularis 0.0093 0.0309 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.1574 0.2947
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0234 0.1641 0.182
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0166 0.0996 0.285
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Loa Loa (eye worm) CDC7 protein kinase 0.0097 0.0339 0.0377
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0093 0.0309 0.053
Echinococcus granulosus carbonic anhydrase 0.0122 0.0583 0.0553
Onchocerca volvulus 0.0154 0.0879 0.1543
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Brugia malayi map kinase activated protein kinase protein 2 0.0424 0.3438 0.3815
Brugia malayi Protein kinase domain containing protein 0.0165 0.099 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1624 0.3044
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0563 0.1899
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.012 0.0563 0.0661
Giardia lamblia Kinase, CMGC CDK 0.0128 0.0635 0.2532
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0109 0.0452 0.3744
Schistosoma mansoni protein kinase 0.0467 0.3842 0.7283
Brugia malayi probable protein kinase 0.0285 0.2122 0.2354
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.009 0.0275 0.0464
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0145 0.0796 0.0952
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0138 0.0735 0.1344
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0261 0.1891 0.2316
Echinococcus granulosus suppressor of cytokine signaling 6 0.0093 0.0309 0.0278
Trypanosoma brucei Casein kinase II 0.0108 0.0445 0.1401
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0319 0.2437 0.2704
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Echinococcus multilocularis mitogen activated protein kinase 3 0.009 0.0278 0.0307
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0907 0.1006
Schistosoma mansoni ephrin receptor 0.0142 0.0764 0.14
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0129 0.0645 0.1757
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0122 0.0583 0.0647
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0093 0.0309 0.0346
Brugia malayi Protein kinase domain containing protein 0.0089 0.0272 0.0301
Echinococcus granulosus tyrosine kinase 0.0166 0.0996 0.0967
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Entamoeba histolytica ankyrin repeat protein 0.0073 0.0113 0.0099
Echinococcus granulosus carbonic anhydrase II 0.0226 0.1563 0.1537
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) hypothetical protein 0.0133 0.0682 0.0756
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0253 0.1818 0.2224
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0122 0.0576 0.1995
Entamoeba histolytica tyrosin kinase, putative 0.0076 0.0145 0.02
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0073 0.0113 0.0215
Entamoeba histolytica PH domain containing protein kinase, putative 0.0178 0.1111 0.3207
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0104 0.0413 0.0458
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0089 0.0272 0.0685
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0075 0.0133 0.0126
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0096 0.0336 0.0941
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.231 0.2285
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0122 0.0576 0.1955
Plasmodium falciparum NIMA related kinase 1 0.0147 0.0812 0.7703
Entamoeba histolytica serine/threonine protein kinase, putative 0.0291 0.2177 0.6523
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0122 0.0583 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0907 0.1672
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.1634 0.6492
Schistosoma mansoni adapter molecule crk 0.0138 0.0727 0.133
Echinococcus multilocularis expressed conserved protein 0.0145 0.0796 0.0952
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1014 0.9013 1
Schistosoma mansoni tyrosine kinase 0.021 0.1414 0.2643
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0093 0.0309 0.0446
Plasmodium falciparum protein kinase 5 0.0128 0.0635 0.5758
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma cruzi casein kinase II, putative 0.0108 0.0445 0.143
Brugia malayi hypothetical protein 0.0073 0.0113 0.0125
Schistosoma mansoni vav2 0.0148 0.0826 0.1518
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0089 0.0272 0.0685
Echinococcus multilocularis rac serine:threonine kinase 0.0178 0.1111 0.1344
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0113 0.0215
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Giardia lamblia Kinase, CMGC CK2 0.0108 0.0445 0.161
Leishmania major protein kinase A catalytic subunit 0.0122 0.0576 0.1995
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis mitogen activated protein kinase 11 0.0319 0.2437 0.2996
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0073 0.0113 0.0101
Brugia malayi Casein kinase II, alpha chain 0.0108 0.0445 0.0494
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0532 0.4458 0.5512
Schistosoma mansoni hypothetical protein 0.0122 0.0583 0.1054
Echinococcus multilocularis nervana 2 0.0133 0.0684 0.0813
Echinococcus granulosus tyrosine protein kinase Src42A 0.019 0.1225 0.1197
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.015 0.084 0.3131
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trichomonas vaginalis protein kinase atn1, putative 0.0073 0.0113 0.0215
Trichomonas vaginalis set domain proteins, putative 0.024 0.1693 0.6732
Echinococcus multilocularis carbonic anhydrase 0.0122 0.0583 0.0687
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Onchocerca volvulus 0.0081 0.0196 0.0229
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0076 0.0142 0.0157
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0291 0.2177 0.2152
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Schistosoma mansoni serine/threonine kinase 0.0181 0.1135 0.2109
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Schistosoma mansoni protein kinase 0.0117 0.0532 0.0956
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0139 0.0735 0.1345
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0096 0.0336 0.0961
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0291 0.2177 0.2672
Schistosoma mansoni tyrosine kinase 0.0305 0.231 0.4354
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Entamoeba histolytica protein kinase, putative 0.0139 0.0735 0.2038
Onchocerca volvulus 0.0166 0.0996 0.1767
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0563 0.1015
Schistosoma mansoni carbonic anhydrase-related 0.0122 0.0583 0.1054
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus nervana 2 0.0133 0.0684 0.0654
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0395 0.3159 0.3895
Loa Loa (eye worm) TK protein kinase 0.0167 0.1008 0.1118
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0138 0.0735 0.1344
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0132 0.067 0.2398
Giardia lamblia Kinase, STE STE20 0.0091 0.0287 0.0848
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0108 0.0445 0.0494
Entamoeba histolytica cell division protein kinase 2, putative 0.0128 0.0635 0.1726
Leishmania major casein kinase, putative 0.0117 0.0532 0.1804
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Brugia malayi Protein kinase domain containing protein 0.0624 0.5325 0.5908
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0032 0.0035
Plasmodium vivax tyrosine kinase-like protein, putative 0.0087 0.025 0.152
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0226 0.1563 0.1735
Echinococcus multilocularis tyrosine protein kinase Blk 0.0261 0.1891 0.2316
Schistosoma mansoni suppressor of cytokine signaling 0.0093 0.0309 0.053
Echinococcus granulosus epidermal growth factor receptor 0.052 0.4346 0.4328
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0181 0.1135 0.1107
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0073 0.0113 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Brugia malayi serine/threonine kinase 12 0.0157 0.0907 0.1006
Brugia malayi protein kinase C3,putative 0.017 0.1031 0.1144
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Echinococcus multilocularis tyrosine protein kinase pr2 0.0073 0.0113 0.0101
Brugia malayi Protein kinase domain containing protein 0.0177 0.1096 0.1216
Echinococcus multilocularis N chimaerin 0.0138 0.0735 0.0876
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0157 0.0907 0.0878
Loa Loa (eye worm) hypothetical protein 0.0088 0.0255 0.0283
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0087 0.025 0.152
Echinococcus multilocularis cyclin dependent kinase 5 0.0128 0.0635 0.0751
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0181 0.1135 0.1374
Entamoeba histolytica hypothetical protein 0.0073 0.0116 0.0109
Echinococcus granulosus cyclin dependent kinase 1 0.0128 0.0635 0.0605
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Brugia malayi Protein kinase domain containing protein 0.0483 0.3991 0.4428
Leishmania major protein kinase, putative 0.0109 0.0452 0.1462
Schistosoma mansoni nephrin 0.013 0.0655 0.1191
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0073 0.0113 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0538 0.0968
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0278 0.0898
Toxoplasma gondii hypothetical protein 0.0122 0.0583 0.2064
Loa Loa (eye worm) CAMK protein kinase 0.0076 0.0142 0.0157
Echinococcus granulosus casein kinase I alpha 0.0117 0.0532 0.0502
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.023 0.1596 0.299
Giardia lamblia Kinase, CMGC SRPK 0.0089 0.0272 0.0771
Echinococcus multilocularis dual specificity protein kinase clk2 0.0165 0.099 0.1193
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.1991 0.3745
Plasmodium falciparum calcium-dependent protein kinase 1 0.0109 0.0452 0.3744
Echinococcus granulosus Vam6:Vps39 protein 0.012 0.0563 0.0533
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0138 0.0727 0.0807
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.009 0.0278 0.0309
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0109 0.0452 0.3744
Brugia malayi Hr1 repeat family protein 0.032 0.2455 0.2724
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0309 0.0278
Echinococcus granulosus CDC7 cell division cycle 7 0.0097 0.0339 0.0309
Schistosoma mansoni cell adhesion molecule 0.0126 0.062 0.1125
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0122 0.0583 0.0647
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Echinococcus multilocularis casein kinase I gamma 0.023 0.1596 0.1948
Schistosoma mansoni hypothetical protein 0.011 0.0463 0.0823
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0218 0.1488 0.1651
Echinococcus multilocularis tensin 0.0093 0.0309 0.0346
Echinococcus granulosus insulin receptor 0.0455 0.373 0.371
Schistosoma mansoni protein kinase 0.0165 0.0985 0.1821
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.021 0.1414 0.2643
Echinococcus multilocularis protein kinase 0.0073 0.0113 0.0101
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis SHC transforming protein 3 0.0093 0.0309 0.0346
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Echinococcus multilocularis cyclin dependent kinase 1 0.0128 0.0635 0.0751
Loa Loa (eye worm) hypothetical protein 0.009 0.0275 0.0305
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.015 0.084 0.3068
Brugia malayi Raf kinase 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Trichomonas vaginalis STE family protein kinase 0.0147 0.0812 0.3098
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0088 0.0255 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.02 0.1317 0.2456
Brugia malayi Guanylyl cyclase protein 23 0.0073 0.0113 0.0125
Brugia malayi Protein kinase domain containing protein 0.0132 0.067 0.0743
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Brugia malayi Protein kinase domain containing protein 0.0166 0.0996 0.1105
Echinococcus granulosus hypothetical protein 0.013 0.0654 0.0624
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0169 0.102 1
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0216 0.1469 0.1442
Schistosoma mansoni GTPase activating protein 0.0093 0.0309 0.053
Plasmodium vivax serine/threonine kinase-1, putative 0.0165 0.099 0.9665
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0132 0.067 0.2398
Loa Loa (eye worm) hypothetical protein 0.011 0.0463 0.0513
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1624 0.3044
Trichomonas vaginalis AGC family protein kinase 0.0181 0.1135 0.4433
Entamoeba histolytica hypothetical protein, conserved 0.0073 0.0113 0.0099
Onchocerca volvulus 0.0073 0.0113 0.0068
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0132 0.067 0.2398
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0226 0.1563 0.6242
Plasmodium falciparum serine/threonine protein kinase 0.0089 0.0272 0.1754
Schistosoma mansoni growth factor receptor-bound protein 0.0138 0.0727 0.133
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.009 0.0278 0.0712
Echinococcus multilocularis carbonic anhydrase 0.0122 0.0583 0.0687
Echinococcus granulosus carbonic anhydrase 0.0122 0.0583 0.0553
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.009 0.0278 0.0712
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0576 0.2128
Brugia malayi casein kinase I 0.0117 0.0532 0.059
Loa Loa (eye worm) casein kinase 0.0194 0.126 0.1398
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.008 0.0178 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0113 0.0154
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0122 0.0576 0.1955
Trypanosoma brucei cdc2-related kinase 1 0.0128 0.0635 0.2203
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Brugia malayi Stress-activated protein kinase jnk-1 0.0285 0.2116 0.2347
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0452 0.0804
Onchocerca volvulus 0.0073 0.0113 0.0068
Schistosoma mansoni hypothetical protein 0.0093 0.0309 0.053
Schistosoma mansoni tyrosine kinase 0.0298 0.2246 0.4232
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Plasmodium vivax serine/threonine protein kinase, putative 0.0089 0.0272 0.1754
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0907 0.349
Echinococcus granulosus mitogen activated protein kinase 3 0.009 0.0278 0.0247
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Plasmodium falciparum protein kinase, putative 0.0108 0.0448 0.37
Echinococcus multilocularis serine:threonine protein kinase 0.0123 0.0587 0.0692
Brugia malayi C-terminal src kinase protein 1 0.0073 0.0113 0.0125
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0073 0.0113 0.0215
Echinococcus multilocularis PAK box P21 Rho binding 0.0069 0.0081 0.0061
Loa Loa (eye worm) hypothetical protein 0.033 0.2548 0.2827
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.428 0.812
Schistosoma mansoni tyrosine kinase 0.0455 0.373 0.7068
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0272 0.0458
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0133 0.0684 0.0654
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0142 0.021
Echinococcus granulosus serine threonine protein kinase nrc 0.0169 0.102 0.0991
Entamoeba histolytica protein kinase, putative 0.011 0.0465 0.1197
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0124 0.0263
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Brugia malayi Variant SH3 domain containing protein 0.0138 0.0727 0.0807
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0128 0.0635 0.0605
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0218 0.1488 0.1651
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis c src tyrosine kinase 0.021 0.1414 0.1722
Giardia lamblia Kinase, CAMK CAMKL 0.0096 0.0336 0.1082
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0156 0.0899 0.108
Loa Loa (eye worm) hypothetical protein 0.0122 0.0576 0.0639
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni atypical protein kinase C 0.0322 0.2466 0.4653
Giardia lamblia Kinase, CK1 Casein kinase 0.0117 0.0532 0.2031
Entamoeba histolytica protein kinase 2, putative 0.0169 0.102 0.2924
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus protein kinase C gamma type 0.0225 0.1552 0.1525
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus cGMP dependent protein kinase 1 0.0145 0.0796 0.0766
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0073 0.0113 0.0081
Echinococcus multilocularis tyrosine protein kinase csk 0.0073 0.0113 0.0101
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0532 0.0623
Echinococcus multilocularis protein kinase 0.0073 0.0113 0.0101
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0122 0.0576 0.0639
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0002 0.0002
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0091 0.0287 0.0753
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.025 0.1788 0.1984
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0073 0.0113 0.0125
Loa Loa (eye worm) CAMK/PIM protein kinase 0.038 0.3014 0.3344
Echinococcus granulosus tyrosine protein kinase pr2 0.0073 0.0113 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0108 0.0448 0.1144
Loa Loa (eye worm) hypothetical protein 0.0154 0.0879 0.0976
Loa Loa (eye worm) AGC/PKA protein kinase 0.0122 0.0576 0.0639
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0089 0.0272 0.0671
Leishmania major protein kinase, putative 0.0165 0.099 0.3773
Trypanosoma brucei RNA helicase, putative 0.0105 0.0416 0.128
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0563 0.1015
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0109 0.0452 0.0422
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0255 0.0803
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis insulin receptor 0.0455 0.373 0.4606
Echinococcus granulosus tyrosine protein kinase Blk 0.0261 0.1891 0.1866
Echinococcus granulosus tyrosine protein kinase Lyn 0.0341 0.2645 0.2622
Loa Loa (eye worm) TK/FAK protein kinase 0.0624 0.5325 0.5908
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0113 0.0125
Plasmodium falciparum cGMP-dependent protein kinase 0.0145 0.0796 0.7529
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0142 0.0157
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0226 0.1563 0.6242
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0157 0.0907 0.2571
Echinococcus multilocularis ephrin type A receptor 4 A 0.0142 0.0764 0.0912
Plasmodium falciparum calcium-dependent protein kinase 4 0.0109 0.0452 0.3744
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0108 0.0448 0.0519
Giardia lamblia Kinase, CMGC MAPK 0.009 0.0278 0.0802
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0117 0.0532 0.059
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis protein tyrosine kinase 0.0617 0.5264 0.6517
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Echinococcus granulosus protein kinase c iota type 0.0315 0.2405 0.238
Brugia malayi Protein kinase domain containing protein 0.0097 0.0339 0.0377
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.02 0.1317 0.1289
Entamoeba histolytica protein kinase, putative 0.0073 0.0116 0.0109
Entamoeba histolytica protein kinase, putative 0.0079 0.0172 0.0283
Brugia malayi Protein kinase domain containing protein 0.0324 0.2485 0.2757
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.5533 0.6139
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0798 0.1465
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0139 0.0735 0.2038
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0234 0.1634 0.1813
Loa Loa (eye worm) hypothetical protein 0.0107 0.0434 0.0482
Loa Loa (eye worm) hypothetical protein 0.0107 0.0434 0.0482
Trypanosoma cruzi cdc2-related kinase 3 0.0128 0.0635 0.2248
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0088 0.0255 0.0224
Trypanosoma cruzi casein kinase, putative 0.0117 0.0532 0.1804
Echinococcus granulosus growth factor receptor bound protein 2 0.014 0.0748 0.0718
Brugia malayi intracellular kinase 0.0139 0.0735 0.0816
Trypanosoma cruzi casein kinase, putative 0.0117 0.0532 0.1804
Schistosoma mansoni tyrosine kinase 0.0396 0.3169 0.5997
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0305 0.231 0.2837
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) TK protein kinase 0.0261 0.1891 0.2099
Echinococcus granulosus expressed conserved protein 0.0093 0.0309 0.0278
Brugia malayi Protein kinase domain containing protein 0.0327 0.252 0.2796
Loa Loa (eye worm) TK protein kinase 0.0073 0.0113 0.0125
Echinococcus multilocularis serine:threonine protein kinase 0.0123 0.0587 0.0692
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Echinococcus granulosus roundabout 2 0.015 0.0841 0.0812
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Loa Loa (eye worm) hypothetical protein 0.0133 0.0682 0.0756
Entamoeba histolytica protein kinase, putative 0.0181 0.1135 0.3282
Loa Loa (eye worm) hypothetical protein 0.042 0.3397 0.3769
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Echinococcus granulosus tyrosine protein kinase Srms 0.0605 0.5146 0.513
Brugia malayi STAT protein, DNA binding domain containing protein 0.0093 0.0309 0.0343
Brugia malayi hypothetical protein 0.0239 0.1687 0.1872
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni tyrosine kinase 0.0116 0.052 0.0932
Loa Loa (eye worm) hypothetical protein 0.0069 0.0077 0.0086
Trypanosoma brucei casein kinase I, isoform 2 0.0117 0.0532 0.1767
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.231 0.2285
Loa Loa (eye worm) TK/Met protein kinase 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.012 0.0563 0.0625
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0139 0.0735 0.0876
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.038 0.3014 0.2992
Entamoeba histolytica hypothetical protein 0.0073 0.0116 0.0109
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Loa Loa (eye worm) AGC/PKA protein kinase 0.0122 0.0576 0.0639
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0073 0.0113 0.0068
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0073 0.0113 0.0081
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) CAMK/PIM protein kinase 0.038 0.3014 0.3344
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0576 0.1041
Loa Loa (eye worm) SH2 domain-containing protein 0.0093 0.0309 0.0343
Schistosoma mansoni tensin 0.0093 0.0309 0.053
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Plasmodium vivax casein kinase 1, putative 0.0117 0.0532 0.462
Onchocerca volvulus 0.0073 0.0113 0.0068
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Schistosoma mansoni protein kinase 0.0467 0.3842 0.7283
Onchocerca volvulus 0.0139 0.0735 0.1266
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Entamoeba histolytica protein kinase, putative 0.0088 0.0255 0.0543
Brugia malayi serine/threonine-protein kinase 6 0.0157 0.0907 0.1006
Brugia malayi P38 map kinase family protein 2 0.0319 0.2437 0.2704
Echinococcus granulosus nervana 2 0.0133 0.0684 0.0654
Schistosoma mansoni tyrosine kinase 0.021 0.1414 0.2643
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0073 0.0113 0.0125
Echinococcus granulosus tyrosine protein kinase HCK 0.0167 0.1008 0.0979
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0234 0.1641 0.182
Entamoeba histolytica receptor protein kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0372 0.2941 0.3264
Echinococcus granulosus tyrosine protein kinase ABL1 0.0389 0.3107 0.3085
Echinococcus granulosus dual specificity 0.015 0.084 0.0811
Echinococcus granulosus cGMP dependent protein kinase 1 0.0145 0.0796 0.0766
Schistosoma mansoni carbonic anhydrase-related 0.0122 0.0583 0.1054
Echinococcus multilocularis nervana 2 0.0133 0.0684 0.0813
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0424 0.3438 0.4243
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0336 0.0581
Mycobacterium ulcerans hypothetical protein 0.0109 0.046 0.5
Toxoplasma gondii histone kinase SNF1, putative 0.0096 0.0336 0.0979
Echinococcus granulosus calcium activated potassium channel 0.0145 0.0798 0.0769
Brugia malayi Temporarily assigned gene name protein 59 0.0139 0.0739 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0124 0.0263
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.009 0.0278 0.0712
Echinococcus granulosus serine:threonine protein kinase N2 0.032 0.2455 0.2431
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0467 0.3842 0.3823
Echinococcus granulosus dual specificity 0.015 0.084 0.0811
Onchocerca volvulus 0.0093 0.0309 0.0446
Entamoeba histolytica PH domain containing protein kinase, putative 0.0131 0.0667 0.1826
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0073 0.0113 0.0125
Entamoeba histolytica hypothetical protein 0.0073 0.0116 0.0109
Trypanosoma cruzi polo-like protein kinase, putative 0.0291 0.2177 0.888
Echinococcus granulosus tensin 0.0093 0.0309 0.0278
Echinococcus multilocularis carbonic anhydrase 0.0122 0.0583 0.0687
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0167 0.1007 0.3906
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0452 0.0524
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Leishmania major protein kinase, putative 0.0108 0.0448 0.1445
Onchocerca volvulus 0.0076 0.0142 0.0124
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0156 0.09 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Trichomonas vaginalis protein tyrosine kinase, putative 0.0073 0.0113 0.0215
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0109 0.0452 0.0422
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0218 0.1488 0.1461
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni hypothetical protein 0.011 0.0463 0.0823
Echinococcus multilocularis tyrosine protein kinase Abl 0.0296 0.2222 0.2728
Onchocerca volvulus 0.0315 0.2399 0.4466
Toxoplasma gondii casein kinase I 0.0117 0.0532 0.1838
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Onchocerca volvulus 0.0093 0.0309 0.0446
Brugia malayi Protein kinase domain containing protein 0.0216 0.1469 0.163
Echinococcus granulosus Glutaredoxin protein 5 0.0133 0.0684 0.0654
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0073 0.0113 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0635 0.237
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0635 0.1153
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Echinococcus multilocularis FL cytokine receptor 0.0073 0.0113 0.0101
Echinococcus multilocularis dual specificity 0.0132 0.067 0.0795
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Onchocerca volvulus 0.0166 0.0996 0.1767
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0073 0.0113 0.0101
Giardia lamblia Kinase, CAMK CAMKL 0.0096 0.0336 0.1082
Onchocerca volvulus 0.008 0.018 0.0197
Entamoeba histolytica protein kinase , putative 0.0157 0.0907 0.2571
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0139 0.0735 0.0816
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0139 0.0735 0.0706
Loa Loa (eye worm) TK/RYK protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0096 0.0334 0.0371
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Entamoeba histolytica protein kinase, putative 0.0089 0.0272 0.0595
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Giardia lamblia Kinase, CMGC DYRK 0.015 0.084 0.3526
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0147 0.022
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.231 0.2285
Echinococcus granulosus titin 0.0076 0.0142 0.011
Echinococcus granulosus c-Jun N-terminal kinases 0.0285 0.2116 0.209
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0532 0.0956
Schistosoma mansoni protein kinase 0.0157 0.0907 0.1672
Giardia lamblia Kinase, NEK 0.0147 0.0812 0.3386
Entamoeba histolytica protein kinase, putative 0.0157 0.0907 0.2571
Loa Loa (eye worm) TK protein kinase 0.0073 0.0113 0.0125
Echinococcus granulosus N chimaerin 0.0138 0.0735 0.0705
Trypanosoma brucei protein kinase, putative 0.0108 0.0448 0.1416
Echinococcus granulosus casein kinase i 0.0117 0.0532 0.0502
Echinococcus multilocularis serine:threonine protein kinase N2 0.032 0.2455 0.3018
Giardia lamblia Kinase, STE STE20 0.0093 0.0301 0.0915
Schistosoma mansoni hypothetical protein 0.0093 0.0309 0.053
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0073 0.0113 0.0154
Echinococcus granulosus activated cdc42 kinase 1 0.0073 0.0113 0.0081
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0169 0.102 1
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1469 0.2747
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0093 0.0309 0.0346
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0074 0.0124 0.0263
Loa Loa (eye worm) hypothetical protein 0.0149 0.0838 0.093
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0286 0.213 0.2614
Echinococcus granulosus casein kinase I alpha 0.0117 0.0532 0.0502
Echinococcus granulosus serine:threonine protein kinase 0.0123 0.0587 0.0557
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.231 0.2837
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.009 0.0278 0.0712
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0255 0.0803
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0093 0.0309 0.0346
Echinococcus multilocularis myosin iiia 0.0091 0.0287 0.0318
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0132 0.067 0.235
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.3438 0.651
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0093 0.0301 0.0336
Loa Loa (eye worm) RNA binding protein 0.0064 0.0032 0.0035
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Echinococcus multilocularis epidermal growth factor receptor 0.052 0.4346 0.5373
Entamoeba histolytica protein kinase domain containing protein 0.0076 0.0145 0.02
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0305 0.231 0.2837
Trypanosoma brucei carbonic anhydrase-like protein 0.0226 0.1563 0.6116
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0169 0.102 0.1231
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0907 0.349
Brugia malayi hypothetical protein 0.0166 0.0996 0.1105
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0532 0.1944
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0128 0.0635 0.0705
Schistosoma mansoni vesicular amine transporter 0.009 0.0275 0.0464
Loa Loa (eye worm) serine/threonine protein kinase 0.0073 0.0113 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.0597 0.2214
Brugia malayi Immunoglobulin I-set domain containing protein 0.0705 0.6092 0.6759
Echinococcus granulosus casein kinase I delta 0.0117 0.0532 0.0502
Echinococcus multilocularis tyrosine protein kinase HCK 0.0167 0.1008 0.1216
Schistosoma mansoni hypothetical protein 0.0073 0.0113 0.0154
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0073 0.0113 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0032 0.0035
Echinococcus granulosus retinal guanylyl cyclase 2 0.0073 0.0113 0.0081
Plasmodium falciparum casein kinase 1 0.0117 0.0532 0.462
Brugia malayi Protein kinase domain containing protein 0.0181 0.1135 0.1259
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0139 0.0735 0.268
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus granulosus expressed protein 0.0089 0.0272 0.0241
Onchocerca volvulus 0.0166 0.0996 0.1767
Schistosoma mansoni tyrosine kinase 0.0106 0.0432 0.0764
Giardia lamblia Kinase, CMGC CDK 0.0128 0.0635 0.2532
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0278 0.0471
Echinococcus granulosus serine:threonine kinase SAD 1 0.0096 0.0336 0.0305
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Onchocerca volvulus 0.0073 0.0113 0.0068
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0073 0.0113 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Echinococcus multilocularis kinase suppressor of Ras 1 0.0073 0.0113 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0587 0.2173
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0122 0.0583 0.0647
Trichomonas vaginalis AGC family protein kinase 0.0203 0.1343 0.5291
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0109 0.0452 0.1489
Trichomonas vaginalis STE family protein kinase 0.0091 0.0287 0.0937
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.1488 0.2784
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Brugia malayi Protein kinase domain containing protein 0.0203 0.1343 0.149
Entamoeba histolytica protein kinase domain containing protein 0.0108 0.0445 0.1134
Brugia malayi Tyrosine-protein kinase abl-1 0.0138 0.0729 0.0809
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0108 0.0448 0.1472
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0093 0.0309 0.0343
Brugia malayi protein unc-22 0.0076 0.0142 0.0157
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0271 0.1991 0.1966
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0339 0.0309
Echinococcus multilocularis protein kinase c iota type 0.0315 0.2405 0.2955
Echinococcus granulosus kinase suppressor of Ras 1 0.0073 0.0113 0.0081
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0165 0.099 0.3773
Brugia malayi putative serine/threonine kinase SADA gamma 0.0096 0.0336 0.0373
Loa Loa (eye worm) hypothetical protein 0.0122 0.0583 0.0647
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Echinococcus multilocularis mitogen activated protein kinase 14 0.0319 0.2437 0.2996
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0271 0.1991 0.2209
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Trypanosoma brucei SNF1-related protein kinases, putative 0.0096 0.0336 0.0941
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0123 0.0587 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Loa Loa (eye worm) TK/FER protein kinase 0.0493 0.4084 0.4531
Trypanosoma brucei protein kinase, putative 0.009 0.0278 0.0698
Plasmodium falciparum protein serine/threonine kinase-1 0.0165 0.099 0.9665
Echinococcus granulosus carbonic anhydrase 0.0122 0.0583 0.0553
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0076 0.0147 0.0143
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Entamoeba histolytica protein kinase domain containing protein 0.0157 0.0907 0.2571
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis calcium dependent protein kinase 0.0073 0.0116 0.0105
Brugia malayi Protein kinase domain containing protein 0.0208 0.1388 0.154
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Brugia malayi jmjC domain containing protein 0.0097 0.0339 0.0377
Entamoeba histolytica hypothetical protein 0.0409 0.3294 1
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.1818 0.3413
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0319 0.2437 1
Entamoeba histolytica protein kinase, putative 0.0079 0.0172 0.0283
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni protein kinase 0.0285 0.2122 0.3995
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0546
Echinococcus multilocularis SH2 motif 0.0093 0.0309 0.0346
Brugia malayi Protein kinase domain containing protein 0.0166 0.0996 0.1105
Echinococcus granulosus tyrosine protein kinase csk 0.0073 0.0113 0.0081
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0091 0.0287 0.0738
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0176 0.1093 0.1212
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0796 0.146
Schistosoma mansoni protein kinase 0.0069 0.0081 0.0093
Loa Loa (eye worm) hypothetical protein 0.0092 0.0299 0.0332
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0073 0.0113 0.0154
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0678
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0546
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0076 0.0147 0.0115
Echinococcus multilocularis protein kinase shaggy 0.0139 0.0735 0.0876
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0705 0.6092 0.6759
Trichomonas vaginalis CAMK family protein kinase 0.0136 0.0712 0.2688
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Brugia malayi serine/threonine protein kinase 6 0.0157 0.0907 0.1006
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Onchocerca volvulus 0.0523 0.4369 0.8254
Loa Loa (eye worm) hypothetical protein 0.0155 0.0887 0.0984
Plasmodium falciparum carbonic anhydrase 0.0122 0.0583 0.5188
Schistosoma mansoni protein kinase 0.0467 0.3842 0.7283
Echinococcus multilocularis serine threonine protein kinase 0.0225 0.1552 0.1893
Echinococcus multilocularis receptor type guanylyl cyclase 0.0073 0.0113 0.0101
Onchocerca volvulus Serine\/threonine kinase homolog 0.0291 0.2177 0.4038
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0319 0.2437 0.9799
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0339 0.1151
Entamoeba histolytica protein kinase, putative 0.0076 0.0147 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.027 0.1977 0.3718
Toxoplasma gondii AGC kinase 0.0122 0.0576 0.2033
Echinococcus granulosus retinal guanylyl cyclase 2 0.0073 0.0113 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Schistosoma mansoni serine/threonine protein kinase 0.035 0.2735 0.5167
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0109 0.0452 0.1432
Loa Loa (eye worm) TK/ROR protein kinase 0.0096 0.0333 0.037
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0635 0.237
Loa Loa (eye worm) hypothetical protein 0.0199 0.1305 0.1448
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0117 0.0532 0.059
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis expressed protein 0.0089 0.0272 0.0299
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0157 0.0907 0.2571
Brugia malayi Receptor family ligand binding region containing protein 0.0073 0.0113 0.0125
Trypanosoma cruzi polo-like protein kinase, putative 0.0291 0.2177 0.888
Schistosoma mansoni tyrosine kinase 0.0286 0.213 0.4011
Echinococcus multilocularis tyrosine protein kinase shark 0.0396 0.3169 0.3908
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.1135 0.2109
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0124 0.0597 0.0567
Loa Loa (eye worm) hypothetical protein 0.0194 0.1264 0.1402
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Echinococcus granulosus rho-associated protein kinase 1 0.035 0.2735 0.2712
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0122 0.0583 0.0647
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0239 0.1687 0.2062
Echinococcus multilocularis signal transduction protein lnk realted 0.0093 0.0309 0.0346
Brugia malayi hypothetical protein 0.0107 0.0434 0.0482
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Loa Loa (eye worm) hypothetical protein 0.0166 0.0996 0.1105
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.009 0.0278 0.0712
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Schistosoma mansoni growth factor receptor-bound protein 0.014 0.0748 0.1368
Echinococcus granulosus c src tyrosine kinase 0.021 0.1414 0.1387
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0336 0.0581
Echinococcus granulosus protein kinase c epsilon type 0.0227 0.1574 0.1547
Brugia malayi Variant SH3 domain containing protein 0.0138 0.0727 0.0807
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0095 0.0328 0.0364
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.015 0.084 0.0932
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0291 0.2177 0.888
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0096 0.0333 0.0376
Brugia malayi RNA binding protein 0.0064 0.0032 0.0035
Brugia malayi Protein kinase domain containing protein 0.0088 0.0255 0.0283
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis NCK adaptor protein 0.014 0.0748 0.0892
Entamoeba histolytica tyrosin kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0472 0.3889 0.3869
Trypanosoma cruzi casein kinase, putative 0.0117 0.0532 0.1804
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0108 0.0448 0.1445
Echinococcus granulosus tyrosine protein kinase csk 0.0073 0.0113 0.0081
Echinococcus multilocularis dual specificity 0.015 0.084 0.1007
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0096 0.0336 0.2461
Brugia malayi C1-like domain containing protein 0.0234 0.1641 0.182
Brugia malayi Pre-SET motif family protein 0.0211 0.1417 0.1573
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0074 0.0124 0.0263
Schistosoma mansoni protein kinase 0.0093 0.0301 0.0515
Loa Loa (eye worm) hypothetical protein 0.0149 0.0838 0.093
Loa Loa (eye worm) AGC/PKN protein kinase 0.032 0.2455 0.2724
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Brugia malayi Variant SH3 domain containing protein 0.0138 0.0735 0.0815
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0305 0.231 0.2837
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0113 0.0154
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0128 0.0635 0.2248
Schistosoma mansoni tyrosine kinase 0.0298 0.2246 0.4232
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0093 0.0309 0.0278
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0124 0.0597 0.0704
Loa Loa (eye worm) hypothetical protein 0.0646 0.5533 0.6139
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.099 0.3833
Loa Loa (eye worm) hypothetical protein 0.025 0.1786 0.1982
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.1096 0.2034
Brugia malayi Protein kinase domain containing protein 0.0234 0.1634 0.1813
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0108 0.0448 0.1416
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0122 0.0576 0.511
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0096 0.0336 0.0961
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Trypanosoma cruzi Protein kinase B 0.0178 0.1111 0.4295
Entamoeba histolytica cell division protein kinase 2, putative 0.0128 0.0635 0.1726
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0138 0.0735 0.0876
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0907 0.349
Echinococcus multilocularis cyclin dependent kinase 0.0128 0.0635 0.0751
Loa Loa (eye worm) hypothetical protein 0.0497 0.4122 0.4573
Brugia malayi Doublecortin family protein 0.0162 0.0961 0.1066
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0138 0.0727 0.133
Entamoeba histolytica protein kinase, putative 0.0167 0.1008 0.2885
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1417 0.1573
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.038 0.3014 0.5648
Trypanosoma cruzi cdc2-related kinase 1 0.0128 0.0635 0.2248
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0032 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0796 0.146
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0073 0.0113 0.0125
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0395 0.3159 0.3505
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0563 0.1937
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Loa Loa (eye worm) TK/ACK protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0113 0.0125
Brugia malayi phosphoinositide-dependent protein kinase I 0.0088 0.0255 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.038 0.3014 0.57
Trypanosoma brucei rac serine-threonine kinase, putative 0.0324 0.2485 1
Schistosoma mansoni tyrosine kinase 0.0455 0.3732 0.7071
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0122 0.0576 0.511
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0395 0.3159 0.3137
Entamoeba histolytica protein kinase, putative 0.0089 0.0272 0.0595
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0678
Leishmania major protein kinase, putative 0.0091 0.0287 0.0753
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) hypothetical protein 0.0107 0.0434 0.0482
Leishmania major carbonic anhydrase-like protein 0.0226 0.1563 0.6242
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0169 0.102 0.3904
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni protein kinase 0.0208 0.1388 0.2593
Loa Loa (eye worm) TK/ABL protein kinase 0.0389 0.3107 0.3448
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0532 0.0623
Brugia malayi Sex muscle abnormal protein 5 0.0138 0.0727 0.0807
Giardia lamblia Kinase, AGC PKA 0.0169 0.102 0.4396
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0226 0.1563 0.2927
Echinococcus granulosus SH2 motif 0.0093 0.0309 0.0278
Loa Loa (eye worm) hypothetical protein 0.0224 0.1544 0.1713
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0109 0.0452 0.3744
Schistosoma mansoni protein kinase 0.0073 0.0113 0.0154
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0165 0.099 0.3773
Echinococcus multilocularis 0.0137 0.0721 0.0858
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Echinococcus granulosus activin receptor type 0.0108 0.0448 0.0418
Loa Loa (eye worm) STAT protein 0.0093 0.0309 0.0343
Echinococcus multilocularis dual specificity 0.015 0.084 0.1007
Schistosoma mansoni tyrosine kinase 0.0617 0.5264 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0493 0.4084 0.5047
Loa Loa (eye worm) hypothetical protein 0.0258 0.1866 0.207
Trypanosoma brucei aurora B kinase 0.0157 0.0907 0.3347
Giardia lamblia Kinase, AGC PKA 0.0122 0.0576 0.2247
Echinococcus multilocularis mitogen activated protein kinase 14 0.0319 0.2437 0.2996
Toxoplasma gondii AGC kinase 0.0314 0.2394 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0226 0.1563 0.1735
Entamoeba histolytica SH2 domain containing protein 0.0093 0.0309 0.0712
Loa Loa (eye worm) hypothetical protein 0.0122 0.0583 0.0647
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0093 0.0309 0.0278
Echinococcus granulosus serine:threonine protein kinase mig 15 0.025 0.1786 0.176
Loa Loa (eye worm) TK protein kinase 0.0331 0.2553 0.2832
Schistosoma mansoni tyrosine kinase 0.0298 0.2246 0.4232
Loa Loa (eye worm) hypothetical protein 0.012 0.0563 0.0625
Schistosoma mansoni tyrosine kinase 0.0305 0.231 0.4354
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0227 0.1574 0.1746
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0233 0.1624 0.1598
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Entamoeba histolytica tyrosin kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis transfer RNA-Thr 0.0073 0.0113 0.0101
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0165 0.099 0.3845
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0336 0.0581
Schistosoma mansoni carbonic anhydrase 0.0122 0.0583 0.1054
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0339 0.1151
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.0597 0.2214
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Schistosoma mansoni serine/threonine-protein kinase 0.0178 0.1111 0.2063
Entamoeba histolytica hypothetical protein 0.0132 0.067 0.1834
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0113 0.0215
Brugia malayi Tensin 0.0093 0.0309 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0253 0.1818 0.1792
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Brugia malayi Protein kinase domain containing protein 0.1014 0.9013 1
Brugia malayi Protein kinase domain 0.0093 0.0301 0.0334
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0073 0.0113 0.0125
Brugia malayi serine/threonine-protein kinase PAK 7 0.025 0.1788 0.1984
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0452 0.1616
Brugia malayi cytokine inducible SH2-containing protein 5 0.0093 0.0309 0.0343
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0498 0.413 0.5104
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0152 0.0229
Echinococcus granulosus activated cdc42 kinase 1 0.0073 0.0113 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) AGC/PKG protein kinase 0.0145 0.0796 0.0883
Entamoeba histolytica protein kinase, putative 0.0129 0.0645 0.1757
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0546
Brugia malayi integrin-linked kinase 0.0073 0.0113 0.0125
Brugia malayi Protein kinase domain containing protein 0.0123 0.0587 0.0652
Echinococcus granulosus tyrosine protein kinase Src64B 0.0305 0.231 0.2285
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0075 0.0133 0.0101
Entamoeba histolytica tyrosin kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0073 0.0113 0.0081
Entamoeba histolytica protein kinase, putative 0.015 0.084 0.2365
Echinococcus granulosus casein kinase ii subunit alpha 0.0108 0.0445 0.0414
Brugia malayi Temporarily assigned gene name protein 59 0.012 0.0563 0.0625
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Brugia malayi p70 ribosomal S6 kinase beta 0.0314 0.2394 0.2656
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.015 0.084 0.3191
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0117 0.0532 0.1804
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis mitogen activated protein kinase 0.009 0.0278 0.0307
Brugia malayi SRC-1 0.0305 0.231 0.2563
Giardia lamblia Protein 21.1 0.0073 0.0113 0.000000057974
Trichomonas vaginalis STE family protein kinase 0.0073 0.0113 0.0215
Brugia malayi Tyrosine-protein kinase abl-1 0.0296 0.2222 0.2465
Brugia malayi Variant SH3 domain containing protein 0.0104 0.0413 0.0458
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0735 0.2784
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0309 0.0343
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0305 0.231 0.2837
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus granulosus suppressor of cytokine signaling 7 0.0093 0.0309 0.0278
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0157 0.0907 0.2571
Brugia malayi STE20-like kinase MST 0.0277 0.204 0.2263
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0226 0.1563 0.1735
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0147 0.0812 0.3064
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0165 0.0985 0.1092
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0073 0.0113 0.0154
Leishmania major casein kinase II, putative 0.0108 0.0445 0.143
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0093 0.0309 0.053
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0162 0.0961 0.1066
Entamoeba histolytica PH domain containing protein kinase, putative 0.0178 0.1111 0.3207
Brugia malayi Protein kinase domain containing protein 0.0166 0.0996 0.1105
Brugia malayi ephrin receptor 1 precursor 0.0105 0.042 0.0466
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0467 0.3842 0.4746
Echinococcus multilocularis Glutaredoxin protein 5 0.0133 0.0684 0.0813
Schistosoma mansoni serine/threonine protein kinase 0.032 0.2455 0.4631
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0907 0.1006
Echinococcus multilocularis rho associated protein kinase 0.035 0.2735 0.3367
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0233 0.1624 0.1598
Echinococcus multilocularis mitogen activated protein kinase 11 0.0319 0.2437 0.2996
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Onchocerca volvulus Serine\/threonine kinase homolog 0.0177 0.1096 0.1959
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0109 0.0452 0.1489
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0108 0.0448 0.1445
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0128 0.0635 0.2248
Echinococcus granulosus receptor type guanylyl cyclase 0.0073 0.0113 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0139 0.0735 0.2038
Echinococcus multilocularis protein KINase family member (kin 25) 0.0073 0.0113 0.0101
Loa Loa (eye worm) TK protein kinase 0.0073 0.0113 0.0125
Onchocerca volvulus 0.0097 0.0339 0.0505
Entamoeba histolytica cysteine surface protein, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) RGC/RGC protein kinase 0.0073 0.0113 0.0125
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0096 0.0333 0.0303
Entamoeba histolytica protein kinase, putative 0.0109 0.0452 0.1157
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.231 0.2837
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0073 0.0113 0.0125
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0907 0.349
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0091 0.0287 0.0753
Echinococcus granulosus cGMP dependent protein kinase 0.0145 0.0796 0.0766
Echinococcus granulosus ephrin type A receptor 4 A 0.0142 0.0764 0.0735
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0678
Loa Loa (eye worm) hypothetical protein 0.0096 0.0334 0.0371
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0226 0.1563 0.2927
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.02 0.1317 0.1461
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis protein kinase c epsilon type 0.0227 0.1574 0.192
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.085 0.1564
Brugia malayi Protein kinase domain containing protein 0.0166 0.0996 0.1105
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0086 0.024 0.0209
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0093 0.0301 0.027
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.009 0.0278 0.0712
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0122 0.0576 0.1995
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0109 0.0452 0.1489
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Schistosoma mansoni rap gtpase-activating protein 0.012 0.0563 0.1015
Onchocerca volvulus 0.0073 0.0113 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Entamoeba histolytica p21-activated kinase 0.0102 0.0392 0.097
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0093 0.0301 0.027
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0096 0.0336 0.0961
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Echinococcus granulosus serine:threonine protein kinase 0.0123 0.0587 0.0557
Echinococcus multilocularis growth factor receptor bound protein 2 0.0138 0.0727 0.0867
Loa Loa (eye worm) TK/ALK protein kinase 0.0327 0.252 0.2796
Brugia malayi SH2 domain containing protein 0.0166 0.0996 0.1105
Loa Loa (eye worm) TK protein kinase 0.0073 0.0113 0.0125
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0117 0.0532 0.059
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0177 0.1096 0.1325
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Onchocerca volvulus 0.0117 0.0532 0.0874
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0339 0.0383
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.015 0.084 0.0932
Echinococcus granulosus aurora kinase A 0.0157 0.0907 0.0878
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0907 0.1006
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0812 0.3098
Echinococcus multilocularis dual specificity 0.015 0.084 0.1007
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0339 0.1151
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0576 0.1041
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.02 0.1317 0.1601
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0133 0.0684 0.0813
Onchocerca volvulus 0.0073 0.0113 0.0068
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0178 0.1111 0.4295
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.067 0.122
Giardia lamblia Kinase, CMGC GSK 0.0139 0.0735 0.3018
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0113 0.0215
Echinococcus multilocularis casein kinase i 0.0117 0.0532 0.0623
Brugia malayi tRNA modification GTPase TrmE family protein 0.0093 0.0309 0.0343
Echinococcus multilocularis casein kinase ii subunit alpha 0.0108 0.0445 0.0514
Toxoplasma gondii AGC kinase 0.0122 0.0576 0.2033
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0169 0.102 0.0991
Plasmodium falciparum serine/threonine protein kinase KIN 0.0096 0.0336 0.2461
Giardia lamblia Kinase, PLK 0.0291 0.2177 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0239 0.1687 0.1661
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0532 0.4458 0.444
Brugia malayi RhoGAP domain containing protein 0.0138 0.0735 0.0815
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Giardia lamblia Kinase, NEK 0.0073 0.0113 0.000000057974
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0285 0.2116 0.2347
Entamoeba histolytica protein kinase, putative 0.0132 0.067 0.1834
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0126 0.0617 0.0685
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus NCK adaptor protein 0.0138 0.0727 0.0698
Loa Loa (eye worm) hypothetical protein 0.013 0.0654 0.0725
Echinococcus granulosus raf serine:threonine protein kinase 0.0118 0.0538 0.0508
Toxoplasma gondii aurora kinase 0.0157 0.0907 0.3481
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0109 0.0452 0.0502
Echinococcus granulosus neuroglian 0.0113 0.0496 0.0465
Schistosoma mansoni protein kinase 0.0108 0.0448 0.0796
Entamoeba histolytica casein kinase, putative 0.0108 0.0445 0.1134
Echinococcus multilocularis death associated protein kinase 1 0.0913 0.806 1
Leishmania major protein kinase, putative 0.0165 0.099 0.3773
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Plasmodium falciparum casein kinase 2, alpha subunit 0.0108 0.0445 0.3662
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0309 0.0346
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus protein kinase 0.0073 0.0113 0.0081
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0093 0.0309 0.0446
Onchocerca volvulus 0.0208 0.1396 0.2536
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0156 0.0899 0.087
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0128 0.0635 0.0705
Echinococcus multilocularis tensin 0.0093 0.0309 0.0346
Leishmania major protein kinase A catalytic subunit isoform 2 0.0122 0.0576 0.1995
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0452 0.0524
Echinococcus multilocularis integrin linked protein kinase 0.0073 0.0113 0.0101
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0096 0.0336 0.0961
Loa Loa (eye worm) TK/CSK protein kinase 0.0073 0.0113 0.0125
Echinococcus multilocularis basement membrane specific heparan sulfate 0.009 0.0275 0.0302
Onchocerca volvulus 0.024 0.1693 0.3107
Echinococcus granulosus cyclin dependent kinase 0.0128 0.0635 0.0605
Echinococcus granulosus Immunoglobulin 0.009 0.0275 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.2116 0.3983
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0305 0.231 0.2285
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Brugia malayi Egg laying defective protein 4 0.0145 0.0796 0.0883
Onchocerca volvulus 0.0149 0.0838 0.1463
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0122 0.0583 0.0647
Trichomonas vaginalis STE family protein kinase 0.0093 0.0301 0.0994
Schistosoma mansoni tyrosine kinase 0.0296 0.2223 0.4189
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.012 0.0563 0.0533
Entamoeba histolytica PH domain containing protein kinase, putative 0.0131 0.0667 0.1826
Entamoeba histolytica protein kinase, putative 0.0132 0.067 0.1834
Echinococcus multilocularis neuroglian 0.0113 0.0496 0.0578
Echinococcus granulosus fibroblast growth factor receptor 4 0.0286 0.213 0.2105
Echinococcus multilocularis roundabout 2 0.015 0.0841 0.1008
Brugia malayi Kinase associated domain 1 family protein 0.011 0.0463 0.0513
Echinococcus granulosus tyrosine protein kinase 0.0331 0.2553 0.2529
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) AGC/NDR protein kinase 0.0181 0.1135 0.1259
Giardia lamblia Kinase, NEK 0.0147 0.0812 0.3386
Giardia lamblia Kinase, CMGC GSK 0.0139 0.0735 0.3018
Schistosoma mansoni tyrosine kinase 0.0455 0.373 0.7068
Echinococcus granulosus mitogen activated protein kinase 14 0.0319 0.2437 0.2413
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0122 0.0576 0.1955
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.231 0.2837
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0208 0.1388 0.154
Schistosoma mansoni protein kinase C mu 0.0234 0.1641 0.3075
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0389 0.3107 0.3831
Echinococcus multilocularis titin 0.0076 0.0142 0.0137
Echinococcus multilocularis cyclin dependent kinase 1 0.0128 0.0635 0.0751
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0181 0.1135 0.1107
Trypanosoma cruzi cdc2-related kinase 1 0.0128 0.0635 0.2248
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Entamoeba histolytica casein kinase, putative 0.0117 0.0532 0.1404
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0073 0.0113 0.0154
Schistosoma mansoni carbonic anhydrase-related 0.0122 0.0583 0.1054
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0314 0.2394 0.2656
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0073 0.0113 0.0101
Echinococcus multilocularis calcium activated potassium channel 0.0145 0.0798 0.0955
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0081 0.0196 0.0359
Trypanosoma brucei protein kinase, putative 0.0139 0.0735 0.2626
Echinococcus granulosus casein kinase I delta 0.0117 0.0532 0.0502
Echinococcus granulosus epidermal growth factor receptor 0.0371 0.2933 0.2911
Brugia malayi Protein kinase c protein 2 0.0125 0.0603 0.067
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0278 0.0898
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.5533 0.6139
Echinococcus granulosus tyrosine protein kinase csk 0.0073 0.0113 0.0081
Entamoeba histolytica protein kinase, putative 0.0157 0.0907 0.2571
Echinococcus granulosus serine:threonine protein kinase N2 0.014 0.0745 0.0716
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0165 0.099 0.1098
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0483 0.3991 0.4428
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0212 0.1434 0.5667
Trichomonas vaginalis STE family protein kinase 0.0093 0.0301 0.0994
Echinococcus multilocularis Protein kinase C, brain isozyme 0.027 0.1977 0.2423
Echinococcus multilocularis epidermal growth factor receptor 0.0371 0.2933 0.3614
Echinococcus multilocularis Immunoglobulin 0.009 0.0275 0.0302
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.2177 0.4099
Echinococcus multilocularis tyrosine protein kinase 0.0331 0.2553 0.314
Echinococcus granulosus tyrosine protein kinase shark 0.0396 0.3169 0.3147
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Loa Loa (eye worm) TK/INSR protein kinase 0.0455 0.373 0.4138
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0305 0.231 0.2837
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0096 0.0336 0.0373
Giardia lamblia Kinase, CDC7 0.0097 0.0339 0.11
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0073 0.0113 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0336 0.0581
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0073 0.0116 0.0109
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0261 0.1891 0.1866
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0145 0.0796 0.0952
Brugia malayi Protein kinase domain containing protein 0.0395 0.3159 0.3505
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0218 0.1488 0.1814
Echinococcus granulosus integrin linked protein kinase 0.0073 0.0113 0.0081
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0093 0.0309 0.0346
Echinococcus multilocularis Immunoglobulin 0.009 0.0275 0.0302
Schistosoma mansoni kinase 0.0311 0.2364 0.4458
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0139 0.0735 0.0816
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0138 0.0735 0.0815
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) TK protein kinase 0.0399 0.32 0.3551
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0233 0.1624 0.1984
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) protein kinase domain-containing protein 0.0073 0.0113 0.0125
Schistosoma mansoni tyrosine kinase 0.052 0.4346 0.8245
Echinococcus multilocularis serine:threonine protein kinase N2 0.014 0.0745 0.0889
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.1687 0.3164
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0635 0.237
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Entamoeba histolytica protein kinase, putative 0.0093 0.0301 0.0687
Trypanosoma brucei cdc2-related kinase 3 0.0128 0.0635 0.2203
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0255 0.0427
Schistosoma mansoni tensin-related 0.0093 0.0309 0.053
Echinococcus multilocularis casein kinase I delta 0.0117 0.0532 0.0623
Loa Loa (eye worm) hypothetical protein 0.0138 0.0727 0.0807
Trichomonas vaginalis CAMK family protein kinase 0.0136 0.0712 0.2688
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0177 0.1096 0.1068
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0073 0.0113 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0093 0.0309 0.0346
Onchocerca volvulus 0.0093 0.0309 0.0446
Echinococcus multilocularis aurora kinase A 0.0157 0.0907 0.109
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0156 0.09 0.0871
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Schistosoma mansoni tensin 0.0093 0.0309 0.053
Echinococcus granulosus Protein kinase C brain isozyme 0.027 0.1977 0.1952
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0286 0.213 0.2105
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0157 0.0907 0.875
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0073 0.0113 0.0154
Loa Loa (eye worm) hypothetical protein 0.0123 0.0587 0.0652
Trichomonas vaginalis AGC family protein kinase 0.0203 0.1343 0.5291
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma brucei polo-like protein kinase 0.0291 0.2177 0.8701
Loa Loa (eye worm) thyroid receptor interactor 0.0126 0.0616 0.0684
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0138 0.0735 0.0705
Schistosoma mansoni tyrosine kinase 0.0371 0.2933 0.5545
Echinococcus granulosus natriuretic peptide receptor 1 0.0073 0.0113 0.0081
Loa Loa (eye worm) hypothetical protein 0.011 0.0461 0.0511
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0091 0.0287 0.0644
Loa Loa (eye worm) SH2 domain-containing protein 0.0093 0.0309 0.0343
Loa Loa (eye worm) hypothetical protein 0.012 0.0563 0.0625
Echinococcus granulosus SHC transforming protein 3 0.0093 0.0309 0.0278
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Brugia malayi protein-tyrosine kinase 0.0261 0.1891 0.2099
Schistosoma mansoni ste20-related kinase 0.0221 0.1514 0.2832
Schistosoma mansoni ephrin receptor 0.009 0.0272 0.0459
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0086 0.024 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.2021 0.3803
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0278 0.0898
Echinococcus multilocularis SH2 motif 0.0093 0.0309 0.0346
Brugia malayi Protein kinase domain containing protein 0.0331 0.2553 0.2832
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0073 0.0113 0.0215
Echinococcus multilocularis 0.013 0.0654 0.0775
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0424 0.3438 0.3815
Plasmodium vivax glycogen synthase kinase 3, putative 0.0139 0.0735 0.6865
Echinococcus granulosus defective proboscis extension response 0.009 0.0275 0.0244
Loa Loa (eye worm) hypothetical protein 0.0093 0.0309 0.0343
Schistosoma mansoni tensin 0.0093 0.0309 0.053
Leishmania major protein kinase A catalytic subunit isoform 1 0.0122 0.0576 0.1995
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus retinal guanylyl cyclase 2 0.0073 0.0113 0.0081
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0233 0.1624 0.1984
Echinococcus multilocularis SH2 motif 0.0093 0.0309 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.015 0.084 0.1545
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0278 0.0898
Brugia malayi SH2 domain containing protein 0.0493 0.4084 0.4531
Loa Loa (eye worm) hypothetical protein 0.0103 0.04 0.0444
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Echinococcus granulosus SH2 domain containing protein 7 0.0093 0.0309 0.0278
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.02 0.1317 0.1461
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Toxoplasma gondii CMGC kinase, CK2 family 0.0108 0.0445 0.1457
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0309 0.0278
Echinococcus granulosus titin 0.0076 0.0142 0.011
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0532 0.0623
Brugia malayi Protein kinase domain containing protein 0.0166 0.0996 0.1105
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.1818 0.3413
Entamoeba histolytica protein kinase, putative 0.0324 0.2485 0.7482
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0239 0.1687 0.1872
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Onchocerca volvulus 0.0093 0.0309 0.0446
Schistosoma mansoni shc transforming protein 0.0093 0.0309 0.053
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0091 0.0287 0.0644
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0291 0.2177 0.2415
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0216 0.1469 0.179
Echinococcus multilocularis serine:threonine protein kinase 3 0.0277 0.204 0.2501
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0165 0.099 0.3773
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0073 0.0113 0.0125
Schistosoma mansoni hypothetical protein 0.012 0.0563 0.1015
Trichomonas vaginalis TK family protein kinase 0.0074 0.0124 0.0263
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) SH2 domain-containing protein 0.0093 0.0309 0.0343
Echinococcus granulosus serine/threonine protein kinase 0.0178 0.1111 0.1083
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0147 0.0812 0.7703
Echinococcus granulosus SH2 motif 0.0093 0.0309 0.0278
Entamoeba histolytica protein kinase, putative 0.0076 0.0147 0.0206
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0073 0.0113 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0798 0.1465
Trichomonas vaginalis STE family protein kinase 0.0069 0.0081 0.0083
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus mitogen activated protein kinase 0.009 0.0278 0.0247
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Plasmodium vivax protein kinase, putative 0.0089 0.0266 0.1692
Onchocerca volvulus 0.0166 0.0996 0.1767
Loa Loa (eye worm) hypothetical protein 0.0149 0.0838 0.093
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0305 0.231 0.2285
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.0158 0.092 0.102
Schistosoma mansoni protein kinase 0.0108 0.0448 0.0796
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0452 0.0524
Echinococcus multilocularis CDC7 cell division cycle 7 0.0097 0.0339 0.0383
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0122 0.0576 0.1995
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.009 0.0278 0.0726
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis activin receptor type 0.0108 0.0448 0.0519
Schistosoma mansoni hypothetical protein 0.0105 0.0416 0.0735
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0165 0.099 0.3697
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0109 0.0452 0.0502
Onchocerca volvulus 0.0097 0.0339 0.0505
Loa Loa (eye worm) TK protein kinase 0.0073 0.0113 0.0125
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0359 0.2816 0.3124
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.038 0.3014 0.3715
Echinococcus granulosus dual specificity 0.0132 0.067 0.064
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0371 0.2933 0.2911
Loa Loa (eye worm) hypothetical protein 0.042 0.3397 0.3769
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0271 0.1991 0.244
Brugia malayi Protein kinase domain containing protein 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0073 0.0113 0.0099
Onchocerca volvulus 0.0199 0.1305 0.2361
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0073 0.0113 0.0125
Leishmania major protein kinase, putative 0.0157 0.0907 0.3416
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0336 0.0794
Onchocerca volvulus 0.0093 0.0309 0.0446
Trypanosoma cruzi cdc2-related kinase 3 0.0128 0.0635 0.2248
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Brugia malayi MAP kinase sur-1 0.009 0.0278 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.2177 0.8729
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Entamoeba histolytica serine/threonine kinase, putative 0.0073 0.0113 0.0099
Trichomonas vaginalis STE family protein kinase 0.0093 0.0301 0.0994
Brugia malayi Protein kinase domain containing protein 0.0067 0.0056 0.0062
Echinococcus multilocularis tyrosine protein kinase csk 0.0073 0.0113 0.0101
Onchocerca volvulus 0.0166 0.0996 0.1767
Loa Loa (eye worm) hypothetical protein 0.009 0.0275 0.0305
Entamoeba histolytica casein kinase 1, putative 0.0117 0.0532 0.1404
Schistosoma mansoni tyrosine kinase 0.0371 0.2933 0.5545
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0087 0.025 0.0605
Onchocerca volvulus Tyrosine kinase homolog 0.0619 0.5277 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0109 0.0452 0.0502
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0319 0.2437 1
Onchocerca volvulus 0.0093 0.0309 0.0446
Entamoeba histolytica hypothetical protein 0.0073 0.0113 0.0099
Schistosoma mansoni tyrosine kinase 0.0073 0.0113 0.0154
Echinococcus granulosus casein kinase I alpha 0.0117 0.0532 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0113 0.0215
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0093 0.0301 0.027
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0088 0.0255 0.0278
Echinococcus granulosus SH2 domain containing adapter protein F 0.0093 0.0309 0.0278
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0132 0.067 0.0743
Onchocerca volvulus 0.0166 0.0996 0.1767
Schistosoma mansoni vam6/vps39 related 0.012 0.0563 0.1015
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0122 0.0576 0.1995
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0073 0.0113 0.0125
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0088 0.0255 0.0283
Entamoeba histolytica ankyrin repeat protein 0.0073 0.0113 0.0099
Brugia malayi SH2 domain containing protein 0.0093 0.0309 0.0343
Plasmodium vivax calcium-dependent protein kinase, putative 0.0109 0.0452 0.3744
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0113 0.0215
Echinococcus multilocularis raf serine:threonine protein kinase 0.0118 0.0538 0.0631
Schistosoma mansoni nck2/grb4 0.0138 0.0727 0.133
Echinococcus multilocularis 0.0165 0.0985 0.1187
Schistosoma mansoni serine/threonine protein kinase 0.027 0.1977 0.3718
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0359 0.2816 0.3124
Brugia malayi Fibronectin type III domain containing protein 0.0107 0.0434 0.0482
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Echinococcus granulosus dual specificity protein kinase clk2 0.0165 0.099 0.0961
Loa Loa (eye worm) TK/FER protein kinase 0.0166 0.0996 0.1105
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0563 0.1937
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0122 0.0576 0.2033
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0089 0.0272 0.0301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0434 0.0482
Onchocerca volvulus 0.0073 0.0113 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.099 0.1831
Loa Loa (eye worm) hypothetical protein 0.0208 0.1396 0.1549
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0165 0.099 0.3773
Plasmodium falciparum glycogen synthase kinase 3 0.0139 0.0735 0.6865
Schistosoma mansoni tensin-related 0.0093 0.0309 0.053
Schistosoma mansoni serine/threonine-protein kinase 0.0178 0.1111 0.2063
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0073 0.0113 0.0101
Entamoeba histolytica protein kinase, putative 0.0324 0.2485 0.7482
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.099 0.1831
Echinococcus granulosus casein kinase I gamma 0.023 0.1596 0.1569
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0139 0.0735 0.268
Echinococcus granulosus signal transduction protein lnk realted 0.0093 0.0309 0.0278
Echinococcus multilocularis activated cdc42 kinase 1 0.0073 0.0113 0.0101
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Brugia malayi hypothetical protein 0.0093 0.0309 0.0343
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0139 0.0735 0.2731
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.009 0.0278 0.0698
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0285 0.2116 0.2595
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0073 0.0113 0.0101
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Echinococcus multilocularis SH2 domain containing protein 7 0.0093 0.0309 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0798 0.1465
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0108 0.0448 0.0418
Echinococcus granulosus NDR protein kinase 0.0181 0.1135 0.1107
Loa Loa (eye worm) TK protein kinase 0.0309 0.2351 0.2609
Brugia malayi Protein kinase domain containing protein 0.0455 0.373 0.4138
Brugia malayi Serine/threonine-protein kinase Pim-3 0.038 0.3014 0.3344
Loa Loa (eye worm) TK/EPH protein kinase 0.016 0.0943 0.1046
Trypanosoma cruzi aurora B kinase, putative 0.0157 0.0907 0.3416
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0277 0.204 0.2263
Echinococcus multilocularis tyrosine kinase 0.0166 0.0996 0.1201
Trichomonas vaginalis AGC family protein kinase 0.0324 0.2485 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0277 0.204 0.2014
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Schistosoma mansoni tyrosine kinase 0.0302 0.2286 0.4308
Schistosoma mansoni protein kinase 0.0108 0.0445 0.0789
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0309 0.0343
Trichomonas vaginalis STE family protein kinase 0.0093 0.0301 0.0994
Onchocerca volvulus 0.0073 0.0113 0.0068
Echinococcus multilocularis tyrosine kinase 0.0073 0.0113 0.0101
Brugia malayi Tyrosine-protein kinase PR2 0.0073 0.0113 0.0125
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Plasmodium falciparum calcium-dependent protein kinase 5 0.0109 0.0452 0.3744
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0576 0.0678
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0498 0.413 0.4111
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0093 0.0301 0.0336
Entamoeba histolytica protein kinase domain containing protein 0.015 0.084 0.2365
Giardia lamblia Kinase, CMGC CLK 0.0165 0.099 0.4249
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0309 0.0346
Entamoeba histolytica receptor protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis tyrosine protein kinase csk 0.0073 0.0113 0.0101
Schistosoma mansoni serine/threonine kinase 0.0234 0.1634 0.3063
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0336 0.1136
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0109 0.0452 0.3744
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0493 0.4084 0.4065
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0339 0.0588
Brugia malayi Protein kinase domain containing protein 0.038 0.3014 0.3344
Onchocerca volvulus 0.012 0.0563 0.0934
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0073 0.0113 0.0215
Loa Loa (eye worm) hypothetical protein 0.009 0.0278 0.0308
Onchocerca volvulus 0.035 0.2735 0.5111
Loa Loa (eye worm) hypothetical protein 0.0154 0.0879 0.0976
Loa Loa (eye worm) hypothetical protein 0.0128 0.0636 0.0706
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0108 0.0445 0.3662
Echinococcus granulosus protein kinase 0.0165 0.0985 0.0956
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus tyrosine kinase 0.0073 0.0113 0.0081
Brugia malayi Cam kinase protein 1 0.0109 0.0452 0.0502
Plasmodium vivax unspecified product 0.0108 0.0445 0.3662
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0128 0.0635 0.0705
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0424 0.3438 0.3417
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Brugia malayi cell division control protein 2 homolog 0.0128 0.0635 0.0705
Loa Loa (eye worm) TK/FER protein kinase 0.0073 0.0113 0.0125
Trypanosoma cruzi casein kinase, putative 0.0117 0.0532 0.1804
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0073 0.0113 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Echinococcus granulosus cyclin dependent kinase 5 0.0128 0.0635 0.0605
Echinococcus granulosus twitchin 0.0149 0.0831 0.0802
Echinococcus granulosus dual specificity 0.015 0.084 0.0811
Brugia malayi hypothetical protein 0.0073 0.0113 0.0125
Schistosoma mansoni suppressor of cytokine signaling 0.0093 0.0309 0.053
Brugia malayi Protein kinase domain containing protein 0.023 0.1596 0.1771
Echinococcus multilocularis tyrosine protein kinase Src42A 0.019 0.1225 0.1486
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0445 0.1585
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0093 0.0301 0.0336
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Brugia malayi protein kinase C II. 0.0227 0.1574 0.1746
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.2351 0.2609
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0076 0.0147 0.0115
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0189 0.1215 0.1348
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0076 0.0147 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0113 0.0215
Echinococcus multilocularis tyrosine protein kinase Srms 0.0261 0.1891 0.2316
Echinococcus granulosus mitogen activated protein kinase 11 0.0319 0.2437 0.2413
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.011 0.0461 0.043
Echinococcus granulosus protein tyrosine kinase 0.0617 0.5264 0.5249
Loa Loa (eye worm) TK/EGFR protein kinase 0.052 0.4346 0.4822
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0157 0.0907 0.109
Schistosoma mansoni signal transduction protein lnk-related 0.0093 0.0309 0.053
Entamoeba histolytica protein kinase, putative 0.0073 0.0113 0.0099
Echinococcus multilocularis hypothetical protein 0.011 0.0463 0.0536
Plasmodium falciparum serine/threonine protein kinase, putative 0.0157 0.0907 0.875
Brugia malayi Protein kinase domain containing protein 0.0227 0.1574 0.1746
Loa Loa (eye worm) carbonic anhydrase 3 0.0226 0.1563 0.1735
Trichomonas vaginalis TKL family protein kinase 0.0073 0.0113 0.0215
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0138 0.0727 0.0807
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0472 0.3889 0.4804
Trichomonas vaginalis CMGC family protein kinase 0.015 0.084 0.3217
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0073 0.0113 0.0101
Plasmodium falciparum calcium-dependent protein kinase 3 0.0109 0.0452 0.3744
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0305 0.231 0.2837
Echinococcus granulosus protein kinase shaggy 0.0139 0.0735 0.0706
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.015 0.084 0.3131
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0113 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0073 0.0113 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0073 0.0113 0.0099
Loa Loa (eye worm) hypothetical protein 0.0073 0.0113 0.0125
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0145 0.0796 0.2995
Echinococcus multilocularis natriuretic peptide receptor 1 0.0073 0.0113 0.0101

Activities

Activity type Activity value Assay description Source Reference
ILS (functional) = 100 % Percent increase in median life span of BDF1 mice with B-16 melanoma at dose 3.1 mg/kg administered intraperitoneally ChEMBL. 6806475
ILS (functional) = 115 % Percent increase in median life span of BDF1 mice with P-388 leukemia at dose 3.1 mg/kg administered intraperitoneally ChEMBL. 6806475

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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