Detailed information for compound 953336

Basic information

Technical information
  • TDR Targets ID: 953336
  • Name: N-(2-dimethylaminoethyl)-2-fluoro-4-[[4-(2-me thyl-3-propan-2-ylimidazol-4-yl)pyrimidin-2-y l]amino]benzamide
  • MW: 425.502 | Formula: C22H28FN7O
  • H donors: 2 H acceptors: 4 LogP: 2.38 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNC(=O)c1ccc(cc1F)Nc1nccc(n1)c1cnc(n1C(C)C)C)C
  • InChi: 1S/C22H28FN7O/c1-14(2)30-15(3)26-13-20(30)19-8-9-25-22(28-19)27-16-6-7-17(18(23)12-16)21(31)24-10-11-29(4)5/h6-9,12-14H,10-11H2,1-5H3,(H,24,31)(H,25,27,28)
  • InChiKey: CNSXYUZUUPJMQL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-dimethylaminoethyl)-2-fluoro-4-[[4-(3-isopropyl-2-methyl-imidazol-4-yl)pyrimidin-2-yl]amino]benzamide
  • N-(2-dimethylaminoethyl)-2-fluoro-4-[[4-(3-isopropyl-2-methyl-4-imidazolyl)-2-pyrimidinyl]amino]benzamide
  • N-(2-dimethylaminoethyl)-2-fluoro-4-[[4-(2-methyl-3-propan-2-yl-imidazol-4-yl)pyrimidin-2-yl]amino]benzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus protein kinase 0.0994 0.0724 0.0709
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0507 0.0253 0.0238
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0659 0.04 0.1095
Entamoeba histolytica protein kinase 2, putative 0.0319 0.0072 0.0708
Loa Loa (eye worm) AUR protein kinase 0.0661 0.0402 0.0387
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Brugia malayi Protein kinase domain containing protein 0.0507 0.0253 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Entamoeba histolytica protein kinase, putative 0.0417 0.0167 0.164
Echinococcus multilocularis kinase suppressor of Ras 1 0.0261 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2446 0.2125 0.2113
Echinococcus granulosus casein kinase I gamma 0.0378 0.0129 0.0114
Echinococcus multilocularis cyclin dependent kinase 1 0.0507 0.0253 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0139 0.0351
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0661 0.0402 0.394
Echinococcus multilocularis cyclin dependent kinase 0.0507 0.0253 0.0253
Trichomonas vaginalis STE family protein kinase 0.0384 0.0135 0.1281
Schistosoma mansoni hypothetical protein 0.0712 0.0452 0.1243
Echinococcus granulosus serine:threonine protein kinase N2 0.1782 0.1484 0.147
Loa Loa (eye worm) protein kinase domain-containing protein 0.0261 0.0016 0.0001
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0261 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0357 0.0109 0.0093
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2089 0.1781 0.1781
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0423 0.0173 0.0158
Echinococcus granulosus c-Jun N-terminal kinases 0.3498 0.3139 0.3129
Echinococcus granulosus serine:threonine kinase SAD 1 0.0388 0.0139 0.0123
Brugia malayi Immunoglobulin I-set domain containing protein 0.0331 0.0084 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Loa Loa (eye worm) TK/EGFR protein kinase 0.1058 0.0785 0.0771
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0712 0.0452 0.0437
Schistosoma mansoni titin 0.0295 0.0049 0.0095
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0661 0.0402 0.0402
Echinococcus granulosus lachesin 0.0295 0.0049 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.367 0.3306 0.3295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0425 0.0175 0.0159
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0365 0.0117 0.0101
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0388 0.0139 0.0139
Echinococcus granulosus integrin linked protein kinase 0.0261 0.0016 0.0001
Giardia lamblia Kinase, NEK 0.0298 0.0052 0.049
Brugia malayi intracellular kinase 0.1226 0.0947 0.0933
Entamoeba histolytica hypothetical protein, conserved 0.0261 0.0016 0.0158
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0327 0.008 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0378 0.0129 0.0324
Giardia lamblia Kinase, CK1 Casein kinase 0.0659 0.04 0.379
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0261 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Giardia lamblia Aurora kinase 0.0661 0.0402 0.3808
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0622 0.0365 0.035
Brugia malayi putative serine/threonine kinase SADA gamma 0.0388 0.0139 0.0123
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1226 0.0947 0.0947
Trypanosoma cruzi casein kinase, putative 0.0659 0.04 0.04
Echinococcus granulosus hypothetical protein 0.0932 0.0664 0.0649
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.2897 0.256 0.725
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0595 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0986 0.0716 0.0702
Loa Loa (eye worm) hypothetical protein 0.0662 0.0403 0.0388
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0388 0.0139 0.0139
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0301 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0661 0.0402 0.4147
Schistosoma mansoni tyrosine kinase 0.3898 0.3525 1
Onchocerca volvulus 0.7343 0.685 1
Plasmodium falciparum serine/threonine protein kinase KIN 0.0388 0.0139 0.1323
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1118 0.0843 0.0843
Schistosoma mansoni tyrosine kinase 0.1439 0.1153 0.3242
Echinococcus multilocularis protein kinase 0.0261 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Leishmania major protein kinase A catalytic subunit isoform 1 0.0812 0.0548 0.0548
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Trichomonas vaginalis STE family protein kinase 0.1338 0.1055 1
Onchocerca volvulus 0.0986 0.0716 0.1024
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0812 0.0548 0.0548
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0365 0.0117 0.0117
Schistosoma mansoni rap gtpase-activating protein 0.0712 0.0452 0.1243
Toxoplasma gondii hypothetical protein 0.085 0.0585 0.611
Echinococcus multilocularis tyrosine protein kinase HCK 0.0713 0.0453 0.0453
Entamoeba histolytica PH domain containing protein kinase, putative 0.0365 0.0117 0.1144
Echinococcus multilocularis cyclin dependent kinase 9 0.0466 0.0215 0.0215
Trypanosoma cruzi casein kinase II, putative 0.026 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.0175 0.0453
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0712 0.0452 0.1243
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis activated cdc42 kinase 1 0.1799 0.15 0.15
Echinococcus multilocularis rac serine:threonine kinase 0.0365 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0712 0.0452 0.0437
Echinococcus granulosus roundabout 2 0.0331 0.0084 0.0068
Echinococcus granulosus tyrosine protein kinase Fyn 0.1118 0.0843 0.0829
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.0172 0.0445
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0595 0.0339 0.0324
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Echinococcus multilocularis roundabout 2 0.0331 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0139 0.0351
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0749 0.0487 0.1345
Loa Loa (eye worm) hypothetical protein 0.0543 0.0288 0.0273
Onchocerca volvulus 0.0488 0.0235 0.0321
Entamoeba histolytica protein kinase domain containing protein 0.0425 0.0175 0.1714
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase, putative 0.0301 0.0055 0.0535
Trichomonas vaginalis STE family protein kinase 0.0407 0.0157 0.1487
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Echinococcus multilocularis tyrosine protein kinase otk 0.0295 0.0049 0.0049
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0388 0.0139 0.0353
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1453 0.1167 0.1153
Brugia malayi Protein kinase domain containing protein 0.7343 0.685 0.6845
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0261 0.0016 0.0001
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0407 0.0157 0.0157
Echinococcus multilocularis cyclin dependent kinase 19 0.1812 0.1513 0.1513
Leishmania major hypothetical protein, conserved 0.0261 0.0016 0.0016
Echinococcus multilocularis protein kinase c epsilon type 0.0749 0.0487 0.0487
Giardia lamblia Kinase, NEK 0.0298 0.0052 0.049
Leishmania major casein kinase II, putative 0.026 0.0016 0.0016
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis serine:threonine protein kinase N2 0.1195 0.0918 0.0918
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.0031 0.0289
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.0016 0.0016
Echinococcus granulosus dual specificity protein kinase clk2 0.1122 0.0847 0.0833
Brugia malayi protein kinase C II. 0.0749 0.0487 0.0473
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1499 0.1211 0.1211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0695 0.0435 0.042
Brugia malayi Protein kinase domain containing protein 0.2069 0.1761 0.1748
Echinococcus granulosus tyrosine protein kinase shark 0.071 0.045 0.0435
Giardia lamblia Kinase, CMGC CLK 0.1122 0.0847 0.8029
Schistosoma mansoni protein kinase 0.2538 0.2213 0.6261
Trichomonas vaginalis STE family protein kinase 0.1338 0.1055 1
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0812 0.0548 0.0533
Trichomonas vaginalis CK1 family protein kinase 0.0659 0.04 0.379
Loa Loa (eye worm) protein kinase domain-containing protein 0.0378 0.0129 0.0114
Echinococcus granulosus tyrosine protein kinase otk 0.0295 0.0049 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.1122 0.0847 0.237
Loa Loa (eye worm) TK/RYK protein kinase 0.0261 0.0016 0.0001
Echinococcus multilocularis serine threonine protein kinase 0.0629 0.0372 0.0372
Trichomonas vaginalis AGC family protein kinase 0.0282 0.0037 0.0347
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0327 0.008 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Brugia malayi protein C17H12.11 0.063 0.0373 0.0358
Echinococcus multilocularis 0.0994 0.0724 0.0724
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0712 0.0452 0.1243
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1516 0.1228 0.1214
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0533
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0301 0.0055 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0633 0.0375 0.1024
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus dual specificity 0.0301 0.0055 0.0039
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) AGC/PKG protein kinase 0.0296 0.005 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0812 0.0548 0.5195
Echinococcus granulosus casein kinase i 0.0659 0.04 0.0385
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.0016 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0425 0.0175 0.016
Schistosoma mansoni tyrosine protein kinase 0.0261 0.0016 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.1122 0.0847 0.8029
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0867 0.0601 0.0587
Schistosoma mansoni protein kinase C mu 0.113 0.0855 0.2392
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0301 0.0055 0.0419
Echinococcus granulosus slit 2 protein 0.0284 0.0039 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0331 0.0084 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1081 0.0808 0.0794
Loa Loa (eye worm) hypothetical protein 0.1538 0.1249 0.1235
Echinococcus multilocularis dual specificity 0.0301 0.0055 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.078 0.0517 0.0503
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1118 0.0843 0.0843
Echinococcus granulosus NCK adaptor protein 0.0405 0.0155 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Entamoeba histolytica protein kinase, putative 0.0384 0.0135 0.1325
Loa Loa (eye worm) hypothetical protein 0.0359 0.0111 0.0095
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.113 0.0855 0.0841
Giardia lamblia Kinase, CMGC DYRK 0.0301 0.0055 0.0517
Schistosoma mansoni serine/threonine protein kinase 0.3498 0.3139 0.89
Loa Loa (eye worm) thyroid receptor interactor 0.0844 0.0579 0.0564
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0402 0.3808
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Plasmodium falciparum protein kinase, putative 0.0261 0.0016 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni protein kinase 0.0994 0.0724 0.2018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Brugia malayi Doublecortin family protein 0.0313 0.0066 0.0051
Trichomonas vaginalis AGC family protein kinase 0.0628 0.037 0.351
Entamoeba histolytica protein kinase, putative 0.0264 0.0019 0.0188
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0261 0.0016 0.0001
Onchocerca volvulus 0.0488 0.0235 0.0321
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0528 0.0274 0.0274
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2446 0.2125 0.2125
Echinococcus multilocularis receptor type guanylyl cyclase 0.0261 0.0016 0.0016
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1122 0.0847 0.0833
Brugia malayi Peroxidasin 0.0298 0.0052 0.0036
Plasmodium falciparum tyrosine kinase-like protein 0.0261 0.0016 0.0006
Echinococcus multilocularis serine:threonine protein kinase N2 0.1782 0.1484 0.1484
Entamoeba histolytica hypothetical protein 0.0264 0.0019 0.0188
Toxoplasma gondii STE kinase 0.0261 0.0016 0.0006
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1118 0.0843 0.0829
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0929 0.0661 0.0661
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0055 0.0111
Echinococcus multilocularis cyclin dependent kinase 9 0.0425 0.0175 0.0175
Echinococcus multilocularis expressed conserved protein 0.0296 0.005 0.005
Brugia malayi EGF-like domain containing protein 0.0284 0.0039 0.0023
Brugia malayi Protein kinase domain containing protein 0.0327 0.008 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Trypanosoma cruzi cdc2-related kinase 3 0.0507 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0696 0.0436 0.0436
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0339 0.0091 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.082 0.0556 0.0542
Echinococcus granulosus tyrosine protein kinase 0.0261 0.0016 0.0001
Schistosoma mansoni tyrosine kinase 0.1118 0.0843 0.2359
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2409 0.2089 0.2089
Echinococcus granulosus activated cdc42 kinase 1 0.1799 0.15 0.1487
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis transfer RNA-Thr 0.1799 0.15 0.15
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.1812 0.1513 0.4265
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0566 0.0311 0.0296
Echinococcus multilocularis MAM 0.0349 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.0016 0.0001
Echinococcus granulosus tyrosine protein kinase HCK 0.0713 0.0453 0.0438
Brugia malayi Protein kinase domain containing protein 0.0359 0.0111 0.0095
Loa Loa (eye worm) TK/ACK protein kinase 0.0261 0.0016 0.0001
Entamoeba histolytica PH domain containing protein kinase, putative 0.0365 0.0117 0.1144
Echinococcus multilocularis protein kinase 0.0261 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0483 0.023 0.0612
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0276 0.0031 0.0031
Brugia malayi C1-like domain containing protein 0.113 0.0855 0.0841
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Brugia malayi Protein kinase domain containing protein 0.0378 0.0129 0.0114
Loa Loa (eye worm) hypothetical protein 0.0349 0.0101 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis tyrosine protein kinase shark 0.071 0.045 0.045
Brugia malayi Protein kinase domain containing protein 0.1301 0.102 0.1006
Schistosoma mansoni serine/threonine protein kinase 0.0659 0.04 0.1095
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0749 0.0487 0.0473
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.0016 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi Raf kinase 0.0261 0.0016 0.0001
Entamoeba histolytica hypothetical protein 0.0264 0.0019 0.0188
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0659 0.04 0.0385
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2328 0.2011 0.1999
Echinococcus multilocularis casein kinase I delta 0.0659 0.04 0.04
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0261 0.0016 0.0153
Echinococcus granulosus tyrosine protein kinase Fyn 0.1118 0.0843 0.0829
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0331 0.0084 0.0068
Brugia malayi hypothetical protein 0.0349 0.0101 0.0086
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1226 0.0947 0.0947
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.1226 0.0947 0.8976
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2328 0.2011 0.1999
Brugia malayi Immunoglobulin I-set domain containing protein 0.1686 0.1391 0.1378
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni protein kinase 0.2502 0.2178 0.6163
Loa Loa (eye worm) hypothetical protein 0.1799 0.15 0.1487
Trypanosoma cruzi protein kinase, putative 0.0261 0.0016 0.0016
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus tyrosine protein kinase Src64B 0.1118 0.0843 0.0829
Giardia lamblia Kinase, NEK 0.0298 0.0052 0.049
Loa Loa (eye worm) hypothetical protein 0.0867 0.0601 0.0587
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi hypothetical protein 0.2897 0.256 0.2548
Loa Loa (eye worm) hypothetical protein 0.0712 0.0452 0.0437
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.0016 0.0016
Echinococcus multilocularis mitogen activated protein kinase 14 1.0608 1 1
Echinococcus granulosus c src tyrosine kinase 0.0666 0.0407 0.0392
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni tyrosine kinase 0.0653 0.0394 0.1079
Brugia malayi SH2 domain containing protein 0.0488 0.0235 0.022
Plasmodium falciparum tyrosine kinase-like protein 0.0261 0.0016 0.0006
Echinococcus granulosus activated cdc42 kinase 1 0.1799 0.15 0.1487
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0407 0.0157 0.0157
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0261 0.0016 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0633 0.0375 0.3554
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Giardia lamblia Kinase, STE STE20 0.1338 0.1055 1
Echinococcus multilocularis Immunoglobulin 0.0659 0.04 0.04
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Trypanosoma brucei protein kinase, putative 0.0451 0.02 0.02
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Brugia malayi cell division control protein 2 homolog 0.0507 0.0253 0.0238
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0261 0.0016 0.0001
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0407 0.0157 0.0157
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0812 0.0548 0.0548
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0492 0.0239 0.0224
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2089 0.1781 0.1768
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0261 0.0016 0.0002
Echinococcus multilocularis epidermal growth factor receptor 0.1058 0.0785 0.0785
Entamoeba histolytica receptor protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis protein KINase family member (kin 25) 0.0853 0.0587 0.0587
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0388 0.0139 0.0139
Brugia malayi Protein kinase domain containing protein 0.1799 0.15 0.1487
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0296 0.005 0.005
Entamoeba histolytica protein kinase domain containing protein 0.1226 0.0947 0.9287
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Brugia malayi Protein kinase domain containing protein 0.0488 0.0235 0.022
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0595 0.0339 0.0324
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.085 0.0585 0.057
Loa Loa (eye worm) hypothetical protein 0.0488 0.0235 0.022
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Leishmania major protein kinase, putative 0.1122 0.0847 0.0847
Loa Loa (eye worm) hypothetical protein 0.0695 0.0435 0.042
Giardia lamblia Kinase, AGC PKA 0.0319 0.0072 0.0685
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1118 0.0843 0.0829
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.005 0.0099
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1499 0.1211 0.1197
Schistosoma mansoni cell adhesion molecule 0.0295 0.0049 0.0095
Echinococcus granulosus aurora kinase A 0.0661 0.0402 0.0387
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0295 0.0049 0.0049
Schistosoma mansoni protein kinase 0.0661 0.0402 0.1101
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.008 0.0183
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0548
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0595 0.0339 0.0339
Schistosoma mansoni serine/threonine kinase 0.0587 0.0331 0.0898
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0307 0.006 0.0045
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0405 0.0155 0.014
Trypanosoma brucei cdc2-related kinase 1 0.0507 0.0253 0.0253
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0298 0.0052 0.0388
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0507 0.0253 0.0238
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1226 0.0947 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.1081 0.0808 0.2258
Schistosoma mansoni tyrosine kinase 0.0653 0.0394 0.1079
Brugia malayi Protein kinase domain containing protein 0.3941 0.3567 0.3557
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) hypothetical protein 0.0995 0.0725 0.0711
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2328 0.2011 0.1999
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0261 0.0016 0.0001
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0595 0.0339 0.0324
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0595 0.0339 0.0339
Trichomonas vaginalis STE family protein kinase 0.1338 0.1055 1
Leishmania major protein kinase, putative 0.0261 0.0016 0.0016
Echinococcus multilocularis epidermal growth factor receptor 0.0913 0.0646 0.0646
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0528 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) hypothetical protein 0.0595 0.0339 0.0324
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0492 0.024 0.024
Plasmodium vivax serine/threonine kinase-1, putative 0.1122 0.0847 0.8928
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0566 0.0311 0.0296
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0296 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) TK/ALK protein kinase 0.518 0.4763 0.4755
Plasmodium vivax calcium-dependent protein kinase, putative 0.0595 0.0339 0.3474
Echinococcus multilocularis protein kinase shaggy 0.1226 0.0947 0.0947
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1081 0.0808 0.0794
Loa Loa (eye worm) TK/EPH protein kinase 0.0346 0.0098 0.0083
Onchocerca volvulus 0.0794 0.0531 0.0753
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0459 0.0208 0.0208
Echinococcus granulosus serine/threonine protein kinase 0.0365 0.0117 0.0101
Schistosoma mansoni ephrin receptor 0.0327 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0405 0.0155 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Plasmodium falciparum calcium-dependent protein kinase 5 0.0595 0.0339 0.3474
Trypanosoma cruzi casein kinase, putative 0.0659 0.04 0.04
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0566 0.0311 0.0841
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0587 0.0331 0.0316
Brugia malayi Protein kinase domain containing protein 0.082 0.0556 0.0542
Schistosoma mansoni hypothetical protein 0.0349 0.0101 0.0245
Leishmania major protein kinase, putative 0.0451 0.02 0.02
Echinococcus granulosus casein kinase I alpha 0.0659 0.04 0.0385
Toxoplasma gondii casein kinase I 0.0659 0.04 0.4127
Toxoplasma gondii aurora kinase 0.0661 0.0402 0.4147
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.0016 0.0016
Echinococcus multilocularis calcium dependent protein kinase 0.0405 0.0156 0.0156
Trypanosoma cruzi casein kinase, putative 0.0659 0.04 0.04
Echinococcus granulosus cyclin dependent kinase 7 0.067 0.0411 0.0396
Loa Loa (eye worm) hypothetical protein 0.0349 0.0101 0.0086
Brugia malayi SH2 domain containing protein 0.0803 0.054 0.0525
Echinococcus granulosus tyrosine protein kinase pr2 0.0261 0.0016 0.0001
Schistosoma mansoni nck2/grb4 0.0405 0.0155 0.0399
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.1644 0.1351 0.3806
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0771 0.0509 0.0494
Loa Loa (eye worm) hypothetical protein 0.0592 0.0336 0.0321
Plasmodium falciparum glycogen synthase kinase 3 0.1226 0.0947 1
Onchocerca volvulus 0.0488 0.0235 0.0321
Schistosoma mansoni tyrosine kinase 0.1439 0.1153 0.3242
Plasmodium falciparum calcium-dependent protein kinase 4 0.0595 0.0339 0.3474
Echinococcus granulosus Immunoglobulin 0.0659 0.04 0.0385
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2538 0.2213 0.2213
Loa Loa (eye worm) serine/threonine protein kinase 0.0261 0.0016 0.0001
Brugia malayi probable protein kinase 0.1707 0.1411 0.1398
Toxoplasma gondii AGC kinase 0.0812 0.0548 0.5717
Plasmodium vivax casein kinase 1, putative 0.0659 0.04 0.4127
Brugia malayi Protein kinase c protein 2 0.0394 0.0145 0.0129
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1122 0.0847 0.0847
Entamoeba histolytica hypothetical protein 0.0395 0.0146 0.1432
Schistosoma mansoni tyrosine kinase 0.0555 0.03 0.0811
Loa Loa (eye worm) CAMK protein kinase 0.0425 0.0175 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.0274 0.0737
Echinococcus granulosus protein kinase shaggy 0.1226 0.0947 0.0933
Trichomonas vaginalis AGC family protein kinase 0.0298 0.0052 0.049
Onchocerca volvulus 0.0468 0.0216 0.0293
Schistosoma mansoni protein kinase 0.0659 0.04 0.1095
Entamoeba histolytica casein kinase, putative 0.0659 0.04 0.3922
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Entamoeba histolytica hypothetical protein 0.0263 0.0018 0.0181
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1301 0.102 0.102
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1122 0.0847 0.0847
Trypanosoma cruzi protein kinase, putative 0.0261 0.0016 0.0016
Echinococcus granulosus cyclin dependent kinase 5 0.0507 0.0253 0.0238
Loa Loa (eye worm) hypothetical protein 0.1111 0.0836 0.0822
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0091 0.0216
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Onchocerca volvulus 0.0488 0.0235 0.0321
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0507 0.0253 0.0238
Echinococcus granulosus hemicentin 1 0.0295 0.0049 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0661 0.0402 0.1101
Loa Loa (eye worm) hypothetical protein 0.085 0.0585 0.057
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0261 0.0016 0.0158
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Schistosoma mansoni roundabout 0.0295 0.0049 0.0095
Entamoeba histolytica protein kinase, putative 0.0713 0.0453 0.4438
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1499 0.1211 0.1197
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0367 0.0118 0.0103
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 1.0608 1 1
Echinococcus multilocularis PAK box P21 Rho binding 0.0384 0.0135 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0396 0.0147 0.1394
Schistosoma mansoni growth factor receptor-bound protein 0.0422 0.0172 0.0445
Loa Loa (eye worm) hypothetical protein 0.0695 0.0435 0.042
Entamoeba histolytica protein kinase domain containing protein 0.0367 0.0118 0.1161
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0803 0.054 0.0525
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0388 0.0139 0.0139
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0388 0.0139 0.0353
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1 0.0729 0.0715
Brugia malayi Tyrosine-protein kinase abl-1 0.14 0.1116 0.1102
Brugia malayi serine/threonine-protein kinase 6 0.0661 0.0402 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.1782 0.1484 0.4183
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1487 0.12 0.12
Schistosoma mansoni protein kinase 0.2538 0.2213 0.6261
Trichomonas vaginalis AGC family protein kinase 0.0587 0.0331 0.3133
Loa Loa (eye worm) AGC/PKA protein kinase 0.0812 0.0548 0.0533
Loa Loa (eye worm) hypothetical protein 0.0779 0.0516 0.0501
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis calcium activated potassium channel 0.036 0.0112 0.0112
Schistosoma mansoni tyrosine kinase 0.071 0.045 0.1237
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0319 0.0072 0.0072
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0388 0.0139 0.0123
Giardia lamblia Kinase, NEK 0.0261 0.0016 0.0153
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus casein kinase I alpha 0.0659 0.04 0.0385
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Loa Loa (eye worm) hypothetical protein 0.0712 0.0452 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.1122 0.0847 0.237
Echinococcus multilocularis tyrosine protein kinase Srms 0.094 0.0672 0.0672
Echinococcus granulosus dual specificity 0.0301 0.0055 0.0039
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.067 0.0411 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1301 0.102 0.1006
Echinococcus granulosus serine:threonine protein kinase 0.0359 0.0111 0.0095
Plasmodium falciparum calcium-dependent protein kinase 3 0.0595 0.0339 0.3474
Trichomonas vaginalis STE family protein kinase 0.0298 0.0052 0.049
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1226 0.0947 0.0933
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0261 0.0016 0.0016
Entamoeba histolytica casein kinase, putative 0.026 0.0016 0.0152
Brugia malayi hypothetical protein 0.0261 0.0016 0.0001
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0417 0.0167 0.164
Trichomonas vaginalis protein kinase atn1, putative 0.0261 0.0016 0.0153
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1338 0.1055 0.1041
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1338 0.1055 0.1041
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0402 0.3808
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.0175 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis aurora kinase A 0.0661 0.0402 0.0402
Schistosoma mansoni ste20-related kinase 0.0369 0.0121 0.03
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Echinococcus granulosus ephrin type A receptor 4 A 0.0327 0.008 0.0065
Trypanosoma cruzi polo-like protein kinase, putative 0.0339 0.0091 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0359 0.0111 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0139 0.0351
Echinococcus granulosus titin 0.0425 0.0175 0.0159
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0483 0.023 0.0215
Onchocerca volvulus 0.0281 0.0036 0.0029
Echinococcus multilocularis dual specificity 0.0301 0.0055 0.0055
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0661 0.0402 0.394
Brugia malayi Protein kinase domain containing protein 0.0761 0.0499 0.0484
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Brugia malayi protein-tyrosine kinase 0.094 0.0672 0.0657
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis protein kinase c iota type 0.0834 0.0569 0.0569
Echinococcus multilocularis tyrosine protein kinase Blk 0.094 0.0672 0.0672
Echinococcus multilocularis neuroglian 0.0331 0.0084 0.0084
Giardia lamblia Kinase, CAMK CAMKL 0.0429 0.0179 0.1692
Echinococcus multilocularis casein kinase I alpha 0.0659 0.04 0.04
Echinococcus multilocularis casein kinase I delta 0.0659 0.04 0.04
Brugia malayi serine/threonine protein kinase 6 0.0661 0.0402 0.0387
Trypanosoma brucei protein kinase, putative 0.0284 0.0039 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Trypanosoma brucei protein kinase, putative 0.1226 0.0947 0.0947
Echinococcus granulosus natriuretic peptide receptor 1 0.0261 0.0016 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Onchocerca volvulus 0.0349 0.0101 0.0125
Onchocerca volvulus 0.0604 0.0347 0.0484
Trypanosoma cruzi cdc2-related kinase 1 0.0507 0.0253 0.0253
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1226 0.0947 0.2655
Schistosoma mansoni protein kinase 0.1707 0.1411 0.3976
Schistosoma mansoni serine/threonine protein kinase 0.1114 0.084 0.2348
Echinococcus multilocularis heat shock protein 70 0.0261 0.0016 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0445 0.0194 0.0179
Loa Loa (eye worm) hypothetical protein 0.094 0.0672 0.0657
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0298 0.0052 0.0388
Echinococcus multilocularis insulin receptor 0.1439 0.1153 0.1153
Schistosoma mansoni protein kinase 0.1338 0.1055 0.2963
Brugia malayi Protein kinase domain containing protein 0.0445 0.0194 0.0179
Echinococcus granulosus tyrosine protein kinase Src42A 0.0696 0.0436 0.0422
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1118 0.0843 0.0843
Loa Loa (eye worm) IKK protein kinase 0.7343 0.685 0.6845
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3498 0.3139 0.3139
Brugia malayi casein kinase I 0.0659 0.04 0.0385
Schistosoma mansoni ephrin receptor 0.0297 0.0051 0.0101
Echinococcus multilocularis casein kinase I gamma 0.0378 0.0129 0.0129
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1499 0.1211 0.1197
Schistosoma mansoni cell adhesion molecule 0.0331 0.0084 0.0194
Brugia malayi Protein kinase domain containing protein 0.0587 0.0331 0.0316
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0388 0.0139 0.0124
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0452 0.0452
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus TGF-beta receptor type-1 0.0929 0.0661 0.0647
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0405 0.0155 0.0399
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0595 0.0339 0.3474
Schistosoma mansoni serine/threonine protein kinase 0.079 0.0527 0.1458
Echinococcus multilocularis tyrosine protein kinase Fyn 0.094 0.0672 0.0672
Loa Loa (eye worm) hypothetical protein 0.0853 0.0587 0.0573
Schistosoma mansoni tyrosine kinase 0.2182 0.187 0.5284
Echinococcus granulosus rho-associated protein kinase 1 0.0794 0.0531 0.0516
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus tyrosine kinase 0.094 0.0672 0.0657
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0112 0.0274
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0429 0.0179 0.175
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0295 0.0049 0.0048
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.0016 0.0158
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0261 0.0016 0.0001
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2328 0.2011 0.2919
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1644 0.1351 0.1338
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2069 0.1761 0.1748
Schistosoma mansoni protein kinase 0.2538 0.2213 0.6261
Schistosoma mansoni tyrosine kinase 0.0455 0.0203 0.0535
Trichomonas vaginalis STE family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0261 0.0016 0.0002
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1301 0.102 0.102
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni protein kinase 0.0451 0.02 0.0525
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0521 0.0267 0.0252
Echinococcus multilocularis casein kinase I alpha 0.0659 0.04 0.04
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0261 0.0016 0.0002
Loa Loa (eye worm) TK/KIN16 protein kinase 0.367 0.3306 0.3295
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0319 0.0072 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.1114 0.084 0.2348
Onchocerca volvulus Serine\/threonine kinase homolog 0.0327 0.008 0.0093
Trypanosoma brucei mitogen-activated protein kinase 3, putative 1.0608 1 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0331 0.0084 0.0084
Echinococcus multilocularis FL cytokine receptor 0.0261 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1118 0.0843 0.0843
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0336 0.0088 0.0073
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.0016 0.0001
Giardia lamblia Kinase, AGC PKA 0.0812 0.0548 0.5195
Entamoeba histolytica cell division protein kinase 2, putative 0.0548 0.0293 0.2874
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi Protein kinase domain containing protein 0.0488 0.0235 0.022
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0451 0.02 0.1976
Schistosoma mansoni hypothetical protein 0.0349 0.0101 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Brugia malayi hypothetical protein 0.0712 0.0452 0.0437
Schistosoma mansoni protein kinase 0.1 0.0729 0.2033
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) hypothetical protein 0.0953 0.0684 0.067
Echinococcus multilocularis dual specificity mitogen activated protein 0.1338 0.1055 0.1055
Brugia malayi STE20-like kinase MST 0.0423 0.0173 0.0158
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0595 0.0339 0.3474
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis dual specificity 0.1301 0.102 0.102
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1475 0.1188 0.1188
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0309 0.0063 0.0615
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0659 0.04 0.1095
Giardia lamblia Kinase, NEK 0.0261 0.0016 0.0153
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.0867 0.0601 0.0587
Brugia malayi Furin-like cysteine rich region family protein 0.1058 0.0785 0.0771
Brugia malayi casein kinase 1, delta 0.0659 0.04 0.0385
Giardia lamblia Kinase, PLK 0.0339 0.0091 0.0865
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0388 0.0139 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0414 0.0164 0.0148
Brugia malayi Serine/threonine-protein kinase SULU 0.2897 0.256 0.2548
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0652 0.0394 0.1078
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0331 0.0084 0.0084
Entamoeba histolytica protein kinase, putative 0.1226 0.0947 0.9287
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0402 0.3808
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0595 0.0339 0.3474
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0331 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0953 0.0684 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Onchocerca volvulus 0.0659 0.04 0.0562
Echinococcus multilocularis neuroglian 0.0857 0.0592 0.0592
Plasmodium vivax protein kinase, putative 0.0276 0.0031 0.0169
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Onchocerca volvulus 0.1226 0.0947 0.1362
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1081 0.0808 0.0808
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0295 0.0049 0.0095
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0365 0.0117 0.0101
Brugia malayi Tyrosine-protein kinase PR2 0.0261 0.0016 0.0001
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Schistosoma mansoni titin 0.0425 0.0175 0.0453
Schistosoma mansoni tyrosine kinase 0.2285 0.1969 0.5567
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.0016 0.0001
Trichomonas vaginalis CK1 family protein kinase 0.0659 0.04 0.379
Trypanosoma cruzi cdc2-related kinase 3 0.0507 0.0253 0.0253
Echinococcus granulosus cyclin dependent kinase 19 0.1812 0.1513 0.1499
Brugia malayi Protein kinase domain containing protein 0.078 0.0517 0.0503
Onchocerca volvulus 0.0867 0.0601 0.0856
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Onchocerca volvulus 0.0712 0.0452 0.0638
Plasmodium falciparum calcium-dependent protein kinase 2 0.0595 0.0339 0.3474
Echinococcus multilocularis cyclin dependent kinase 1 0.0507 0.0253 0.0253
Brugia malayi Stress-activated protein kinase jnk-1 0.3498 0.3139 0.3129
Loa Loa (eye worm) hypothetical protein 0.0594 0.0338 0.0323
Trypanosoma cruzi aurora B kinase, putative 0.0661 0.0402 0.0402
Giardia lamblia Kinase, CMGC CDK 0.0507 0.0253 0.2401
Giardia lamblia Kinase 0.0261 0.0016 0.0153
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0533
Brugia malayi serine/threonine-protein kinase plk-2 0.0339 0.0091 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Echinococcus granulosus epidermal growth factor receptor 0.1058 0.0785 0.0771
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0548
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1114 0.084 0.084
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis mitogen activated protein kinase 14 1.0608 1 1
Echinococcus granulosus Vam6:Vps39 protein 0.0712 0.0452 0.0437
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0488 0.0235 0.2307
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0055 0.0517
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0507 0.0253 0.0253
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1226 0.0947 1
Loa Loa (eye worm) hypothetical protein 0.0659 0.04 0.0385
Echinococcus multilocularis hemicentin 1 0.0295 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Loa Loa (eye worm) TK/FER protein kinase 0.0803 0.054 0.0525
Echinococcus multilocularis hemicentin 1 0.0295 0.0049 0.0049
Trypanosoma brucei rac serine-threonine kinase, putative 0.0761 0.0499 0.0499
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0451 0.02 0.1957
Brugia malayi Protein kinase domain containing protein 0.1122 0.0847 0.0833
Trichomonas vaginalis AGC family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1453 0.1167 0.1167
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1118 0.0843 0.0843
Plasmodium vivax tyrosine kinase-like protein, putative 0.0261 0.0016 0.0006
Echinococcus multilocularis serine:threonine protein kinase 0.0359 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.2328 0.2011 0.1999
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0853 0.0587 0.0573
Schistosoma mansoni neuroglian 0.0331 0.0084 0.0194
Echinococcus multilocularis cyclin dependent kinase 7 0.067 0.0411 0.0411
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Brugia malayi Egg laying defective protein 4 0.0296 0.005 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0016 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0451 0.02 0.0184
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0282 0.0037 0.0021
Entamoeba histolytica protein kinase, putative 0.0715 0.0455 0.4459
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3498 0.3139 0.3129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0339 0.0091 0.0091
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0088 0.0208
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0319 0.0072 0.0609
Schistosoma mansoni tyrosine kinase 0.1118 0.0843 0.2359
Loa Loa (eye worm) TK/INSR protein kinase 0.1439 0.1153 0.114
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0331 0.0084 0.0194
Onchocerca volvulus 0.0436 0.0185 0.0247
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0339 0.0091 0.0076
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0712 0.0452 0.0452
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1338 0.1055 0.1055
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Brugia malayi SRC-1 0.1118 0.0843 0.0829
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0357 0.0109 0.0093
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0296 0.005 0.0372
Schistosoma mansoni protein kinase 0.0384 0.0135 0.0341
Echinococcus multilocularis casein kinase ii subunit alpha 0.026 0.0016 0.0016
Brugia malayi Hr1 repeat family protein 0.1782 0.1484 0.147
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0468 0.0216 0.0216
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0812 0.0548 0.0548
Brugia malayi Protein kinase domain containing protein 0.0488 0.0235 0.022
Leishmania major protein kinase A catalytic subunit 0.0812 0.0548 0.0548
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0367 0.0118 0.0118
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0261 0.0016 0.0001
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1122 0.0847 0.0847
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2328 0.2011 0.1999
Giardia lamblia Kinase, CMGC GSK 0.1226 0.0947 0.8976
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Schistosoma mansoni tyrosine kinase 0.0666 0.0407 0.1115
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0261 0.0016 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.082 0.0556 0.0542
Schistosoma mansoni adapter molecule crk 0.0405 0.0155 0.0399
Loa Loa (eye worm) hypothetical protein 0.0331 0.0084 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0507 0.0253 0.2401
Schistosoma mansoni serine/threonine protein kinase 0.179 0.1491 0.4204
Echinococcus granulosus beta-adrenergic receptor kinase 0.0336 0.0088 0.0073
Brugia malayi Variant SH3 domain containing protein 0.0388 0.0139 0.0124
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus tyrosine protein kinase Src42A 0.1118 0.0843 0.0829
Loa Loa (eye worm) TK/ROR protein kinase 0.0459 0.0208 0.0193
Echinococcus granulosus MAM 0.0349 0.0101 0.0086
Schistosoma mansoni serine/threonine RGC 0.0261 0.0016 0.0002
Echinococcus multilocularis integrin linked protein kinase 0.0261 0.0016 0.0016
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0261 0.0016 0.0001
Plasmodium falciparum protein serine/threonine kinase-1 0.1122 0.0847 0.8928
Schistosoma mansoni serine/threonine protein kinase 0.1453 0.1167 0.328
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2897 0.256 0.2548
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Echinococcus granulosus TGF beta receptor type 1 0.0929 0.0661 0.0647
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0661 0.0402 0.394
Echinococcus granulosus activin receptor type 0.4224 0.3841 0.3831
Brugia malayi hypothetical protein 0.0695 0.0435 0.042
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0261 0.0016 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0331 0.0898
Brugia malayi Cam kinase protein 1 0.0595 0.0339 0.0324
Echinococcus granulosus mitogen activated protein kinase 14 1.0608 1 1
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0367 0.0118 0.0103
Schistosoma mansoni protein kinase 0.0451 0.02 0.0525
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Entamoeba histolytica protein kinase, putative 0.043 0.018 0.1761
Loa Loa (eye worm) hypothetical protein 0.0779 0.0516 0.0501
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Leishmania major protein kinase, putative 0.0661 0.0402 0.0402
Entamoeba histolytica hypothetical protein 0.1301 0.102 1
Echinococcus granulosus Protein kinase C brain isozyme 0.079 0.0527 0.0513
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.094 0.0672 0.0657
Echinococcus granulosus protein tyrosine kinase 0.3898 0.3525 0.3515
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0261 0.0016 0.0002
Schistosoma mansoni septate junction protein 0.0295 0.0049 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2502 0.2178 0.2178
Onchocerca volvulus Slit protein homolog 0.0284 0.0039 0.0033
Schistosoma mansoni septate junction protein 0.0295 0.0049 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis serine:threonine protein kinase N2 0.0587 0.0331 0.0331
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.0031 0.0289
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase, putative 0.1301 0.102 1
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0327 0.008 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Trichomonas vaginalis STE family protein kinase 0.0407 0.0157 0.1487
Leishmania major protein kinase, putative 0.1122 0.0847 0.0847
Schistosoma mansoni vesicular amine transporter 0.0659 0.04 0.1095
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0903 0.0635 0.0621
Brugia malayi Prion-like- 0.0295 0.0049 0.0033
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0794 0.0531 0.1468
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0313 0.0066 0.0051
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Echinococcus granulosus peroxidasin 0.0298 0.0052 0.0036
Loa Loa (eye worm) hypothetical protein 0.0388 0.0139 0.0123
Loa Loa (eye worm) hypothetical protein 0.1454 0.1167 0.1154
Trichomonas vaginalis STE family protein kinase 0.0407 0.0157 0.1487
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.0339 0.3214
Schistosoma mansoni serine/threonine protein kinase 0.067 0.0411 0.1128
Schistosoma mansoni tyrosine kinase 0.0666 0.0407 0.1115
Echinococcus granulosus casein kinase I delta 0.0659 0.04 0.0385
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0407 0.0157 0.0142
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.085 0.0585 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0118 0.0293
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0595 0.0339 0.3474
Schistosoma mansoni tyrosine kinase 0.0913 0.0646 0.1796
Trypanosoma cruzi casein kinase, putative 0.0659 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.085 0.0585 0.057
Echinococcus multilocularis slit 2 protein 0.0284 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0139 0.0351
Loa Loa (eye worm) hypothetical protein 0.048 0.0228 0.0213
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0088 0.0208
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0274 0.0029 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Trichomonas vaginalis CMGC family protein kinase 0.0507 0.0253 0.2401
Brugia malayi C-terminal src kinase protein 1 0.0261 0.0016 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus calcium activated potassium channel 0.036 0.0112 0.0096
Echinococcus granulosus protein kinase c epsilon type 0.0749 0.0487 0.0473
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Brugia malayi hypothetical protein 0.063 0.0373 0.0358
Leishmania major protein kinase A catalytic subunit isoform 2 0.0812 0.0548 0.0548
Entamoeba histolytica protein kinase, putative 0.0407 0.0157 0.1539
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Trichomonas vaginalis STE family protein kinase 0.0407 0.0157 0.1487
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.078 0.0517 0.0503
Echinococcus granulosus tyrosine kinase 0.0488 0.0235 0.022
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 1.0608 1 1
Echinococcus multilocularis cyclin dependent kinase 5 0.0507 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0273 0.0028 0.0013
Brugia malayi Variant SH3 domain containing protein 0.0405 0.0155 0.014
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Brugia malayi Protein kinase domain containing protein 0.078 0.0517 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Echinococcus multilocularis dual specificity 0.0301 0.0055 0.0055
Giardia lamblia Kinase, CMGC GSK 0.1226 0.0947 0.8976
Brugia malayi protein unc-22 0.0425 0.0175 0.0159
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.0274 0.0737
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0402 0.3808
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0295 0.0049 0.0033
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1475 0.1188 0.1174
Onchocerca volvulus 0.2655 0.2326 0.338
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0278 0.0032 0.0017
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.063 0.0373 0.0358
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0659 0.04 0.0385
Entamoeba histolytica serine/threonine protein kinase, putative 0.0339 0.0091 0.0895
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0091 0.0865
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Loa Loa (eye worm) hypothetical protein 0.0659 0.04 0.0385
Echinococcus granulosus tyrosine protein kinase ABL1 0.2409 0.2089 0.2077
Loa Loa (eye worm) AGC/NDR protein kinase 0.0587 0.0331 0.0316
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.02 0.02
Loa Loa (eye worm) AUR protein kinase 0.0661 0.0402 0.0387
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2283 0.1968 0.1955
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1812 0.1513 0.1499
Giardia lamblia Kinase, AGC AKT 0.1057 0.0784 0.7432
Echinococcus multilocularis Protein kinase C, brain isozyme 0.079 0.0527 0.0527
Loa Loa (eye worm) hypothetical protein 0.0695 0.0435 0.042
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0587 0.0331 0.0316
Entamoeba histolytica PH domain containing protein kinase, putative 0.0858 0.0593 0.581
Brugia malayi Protein kinase domain containing protein 0.1439 0.1153 0.114
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Echinococcus multilocularis peroxidasin 0.0298 0.0052 0.0052
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0595 0.0339 0.3474
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2897 0.256 0.256
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0407 0.0157 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi Protein kinase domain containing protein 0.1812 0.1513 0.1499
Loa Loa (eye worm) hypothetical protein 0.0316 0.007 0.0054
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.02 0.02
Echinococcus granulosus cGMP dependent protein kinase 1 0.0296 0.005 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0444 0.0193 0.0178
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1122 0.0847 0.8928
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.1301 0.102 0.2862
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.0016 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Trypanosoma brucei casein kinase I, isoform 2 0.0659 0.04 0.04
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0261 0.0016 0.0001
Echinococcus multilocularis roundabout 2 0.0331 0.0084 0.0084
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.067 0.0411 0.0396
Leishmania major protein kinase, putative 0.0595 0.0339 0.0339
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0623 0.0365 0.035
Toxoplasma gondii protein kinase domain-containing protein 0.0261 0.0016 0.0006
Onchocerca volvulus Serine\/threonine kinase homolog 0.0339 0.0091 0.011
Toxoplasma gondii AGC kinase 0.0715 0.0455 0.4714
Loa Loa (eye worm) hypothetical protein 0.0543 0.0288 0.0273
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0261 0.0016 0.0001
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.0253 0.0678
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0507 0.0253 0.0238
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Leishmania major casein kinase, putative 0.0659 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Echinococcus granulosus tyrosine protein kinase Srms 0.0912 0.0645 0.063
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0331 0.0898
Schistosoma mansoni protein kinase 0.0407 0.0157 0.0403
Echinococcus granulosus kinase suppressor of Ras 1 0.0261 0.0016 0.0001
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1338 0.1055 0.1055
Echinococcus multilocularis twitchin 0.0389 0.014 0.014
Entamoeba histolytica protein kinase domain containing protein 0.1226 0.0947 0.9287
Schistosoma mansoni tyrosine kinase 0.0913 0.0646 0.1796
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus tyrosine kinase 0.0261 0.0016 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.0016 0.0001
Schistosoma mansoni cell adhesion molecule 0.0331 0.0084 0.0194
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0388 0.0139 0.0124
Entamoeba histolytica protein kinase , putative 0.0661 0.0402 0.394
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0754 0.0493 0.0478
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1338 0.1055 0.1055
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni growth factor receptor-bound protein 0.0405 0.0155 0.0399
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5672 0.5237 0.523
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0263 0.0018 0.0175
Schistosoma mansoni serine/threonine-protein kinase 0.0365 0.0117 0.0288
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0388 0.0139 0.0139
Echinococcus multilocularis casein kinase i 0.0659 0.04 0.04
Loa Loa (eye worm) TK protein kinase 0.094 0.0672 0.0657
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0666 0.0407 0.1115
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1499 0.1211 0.1197
Schistosoma mansoni protein tyrosine kinase 0.0261 0.0016 0.0002
Entamoeba histolytica casein kinase 1, putative 0.0659 0.04 0.3922
Echinococcus multilocularis death associated protein kinase 1 0.9403 0.8837 0.8837
Loa Loa (eye worm) AGC/PKN protein kinase 0.1782 0.1484 0.147
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Loa Loa (eye worm) SRC-1 0.1118 0.0843 0.0829
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2502 0.2178 0.2166
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Brugia malayi hypothetical protein 0.0261 0.0016 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Trichomonas vaginalis TK family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus cyclin dependent kinase 9 0.0425 0.0175 0.016
Echinococcus granulosus serine:threonine protein kinase 0.0359 0.0111 0.0095
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase, putative 0.0661 0.0402 0.394
Entamoeba histolytica protein kinase, putative 0.043 0.018 0.1761
Loa Loa (eye worm) TK protein kinase 0.0713 0.0453 0.0438
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1942 0.1638 0.1625
Onchocerca volvulus 0.0368 0.012 0.0152
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus protein kinase 0.0261 0.0016 0.0001
Brugia malayi ephrin receptor 1 precursor 0.0292 0.0046 0.0031
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1114 0.084 0.0825
Echinococcus granulosus cyclin dependent kinase 9 0.0466 0.0215 0.0199
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0405 0.0155 0.014
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1942 0.1638 0.1625
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0595 0.0339 0.0324
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Onchocerca volvulus 0.0425 0.0175 0.0232
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1301 0.102 0.102
Echinococcus granulosus growth factor receptor bound protein 2 0.0422 0.0172 0.0156
Giardia lamblia Protein 21.1 0.0261 0.0016 0.0153
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1103 0.0829 0.0829
Echinococcus multilocularis growth factor receptor bound protein 2 0.0405 0.0155 0.0155
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0319 0.0072 0.0609
Brugia malayi Protein kinase domain containing protein 0.5182 0.4764 0.4756
Schistosoma mansoni hypothetical protein 0.0261 0.0016 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0587 0.0331 0.3133
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0812 0.0548 0.5717
Loa Loa (eye worm) TK/ABL protein kinase 0.2409 0.2089 0.2077
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Schistosoma mansoni nephrin 0.0331 0.0084 0.0194
Loa Loa (eye worm) AUR protein kinase 0.0661 0.0402 0.0387
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Echinococcus granulosus dual specificity 0.0301 0.0055 0.0039
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1644 0.1351 0.1338
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1118 0.0843 0.0843
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.102 1
Echinococcus multilocularis tyrosine protein kinase 0.0261 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.2328 0.2011 0.5685
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus protein kinase C gamma type 0.0629 0.0372 0.0357
Echinococcus multilocularis NCK adaptor protein 0.0422 0.0172 0.0172
Schistosoma mansoni tyrosine kinase 0.0653 0.0394 0.1079
Loa Loa (eye worm) TK/DDR protein kinase 0.0414 0.0164 0.0148
Trypanosoma cruzi cdc2-related kinase 1 0.0507 0.0253 0.0253
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0261 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0112 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0112 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0622 0.0365 0.0365
Echinococcus granulosus twitchin 0.1047 0.0775 0.0761
Echinococcus multilocularis mitogen activated protein kinase 11 1.0608 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0659 0.04 0.379
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.0016 0.0153
Plasmodium vivax tyrosine kinase-like protein, putative 0.0261 0.0016 0.0006
Loa Loa (eye worm) gastrulation defective protein 1 0.1621 0.1329 0.1316
Loa Loa (eye worm) hypothetical protein 0.0261 0.0016 0.0001
Echinococcus granulosus protein kinase c iota type 0.0834 0.0569 0.0555
Echinococcus multilocularis serine:threonine protein kinase 0.0359 0.0111 0.0111
Echinococcus multilocularis tyrosine kinase 0.0261 0.0016 0.0016
Plasmodium vivax glycogen synthase kinase 3, putative 0.1226 0.0947 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0307 0.006 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1122 0.0847 0.0847
Entamoeba histolytica serine/threonine protein kinase, putative 0.0388 0.0139 0.1361
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.0016 0.0158
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Onchocerca volvulus 0.0488 0.0235 0.0321
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0507 0.0253 0.0253
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0261 0.0016 0.0006
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0812 0.0548 0.5717
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0278 0.0032 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0445 0.0194 0.1838
Schistosoma mansoni protein kinase 0.0407 0.0157 0.0403
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0451 0.02 0.02
Echinococcus granulosus receptor type guanylyl cyclase 0.0261 0.0016 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Giardia lamblia Kinase, CAMK CAMKL 0.0429 0.0179 0.1692
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0276 0.0031 0.0015
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0595 0.0339 0.0324
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0587 0.0331 0.0331
Echinococcus granulosus tyrosine protein kinase Blk 0.094 0.0672 0.0657
Toxoplasma gondii AGC kinase 0.0812 0.0548 0.5717
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0261 0.0016 0.0153
Loa Loa (eye worm) hypothetical protein 0.1029 0.0757 0.0743
Trypanosoma brucei SNF1-related protein kinases, putative 0.0388 0.0139 0.0139
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.0016 0.0158
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0261 0.0016 0.0153
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0301 0.0055 0.0039
Echinococcus multilocularis serine:threonine protein kinase 38 0.0587 0.0331 0.0331
Brugia malayi cyclin-dependent kinase 7 homolog 0.0712 0.0451 0.0436
Echinococcus multilocularis rho associated protein kinase 0.0794 0.0531 0.0531
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0903 0.0635 0.0635
Brugia malayi map kinase activated protein kinase protein 2 0.0566 0.0311 0.0296
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.0016 0.0001
Onchocerca volvulus 0.0779 0.0516 0.0731
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0528 0.0274 0.0259
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Schistosoma mansoni atypical protein kinase C 0.0841 0.0576 0.1596
Echinococcus granulosus casein kinase I delta 0.0659 0.04 0.0385
Echinococcus multilocularis tyrosine protein kinase pr2 0.0261 0.0016 0.0016
Brugia malayi Guanylyl cyclase protein 23 0.0261 0.0016 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Trypanosoma brucei Flagellum attachment zone protein 20 0.0261 0.0016 0.0016
Entamoeba histolytica protein kinase, putative 0.0661 0.0402 0.394
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.0016 0.0001
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0492 0.024 0.0225
Loa Loa (eye worm) TK/CSK protein kinase 0.0261 0.0016 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) TK/Met protein kinase 0.0261 0.0016 0.0001
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0659 0.04 0.0385
Schistosoma mansoni protein kinase 0.0929 0.0661 0.1839
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.079 0.0527 0.1458
Schistosoma mansoni kinase 0.0406 0.0157 0.0402
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1487 0.12 0.1186
Brugia malayi protein kinase C3,putative 0.0438 0.0187 0.0172
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0339 0.0091 0.0091
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0661 0.0402 0.0387
Brugia malayi Protein kinase domain containing protein 0.0855 0.0589 0.0575
Echinococcus granulosus epidermal growth factor receptor 0.0913 0.0646 0.0631
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0261 0.0016 0.0001
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0595 0.0339 0.3474
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.0016 0.0016
Entamoeba histolytica cell division protein kinase 2, putative 0.0507 0.0253 0.2484
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Schistosoma mansoni cell adhesion molecule 0.0791 0.0527 0.1458
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0388 0.0139 0.0139
Echinococcus granulosus NDR protein kinase 0.0587 0.0331 0.0316
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0261 0.0016 0.0001
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2538 0.2213 0.2201
Echinococcus multilocularis protein tyrosine kinase 0.3898 0.3525 0.3525
Loa Loa (eye worm) TK protein kinase 0.1686 0.1391 0.1378
Loa Loa (eye worm) hypothetical protein 0.0298 0.0052 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.0235 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0264 0.0019 0.0188
Trypanosoma brucei aurora B kinase 0.0661 0.0402 0.0402
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Entamoeba histolytica receptor protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.0016 0.0016
Entamoeba histolytica tyrosin kinase, putative 0.0309 0.0063 0.0615
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0812 0.0548 0.0548
Loa Loa (eye worm) TK/FAK protein kinase 0.3941 0.3567 0.3557
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1118 0.0843 0.0843
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) hypothetical protein 0.0932 0.0664 0.0649
Echinococcus granulosus contactin 0.0331 0.0084 0.0068
Echinococcus multilocularis mitogen activated protein kinase 11 1.0608 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.0365 0.0117 0.0288
Echinococcus granulosus raf serine:threonine protein kinase 0.0422 0.0172 0.0156
Giardia lamblia Kinase, CMGC CDK 0.0507 0.0253 0.2401
Loa Loa (eye worm) hypothetical protein 0.0284 0.0039 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0595 0.0339 0.0922
Loa Loa (eye worm) TK protein kinase 0.0576 0.0321 0.0306
Loa Loa (eye worm) hypothetical protein 0.078 0.0517 0.0503
Brugia malayi serine/threonine-protein kinase PAK 7 0.2283 0.1968 0.1955
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0451 0.02 0.02
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0587 0.0331 0.0316
Brugia malayi p70 ribosomal S6 kinase beta 0.0715 0.0455 0.044
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0425 0.0175 0.0159
Entamoeba histolytica protein kinase, putative 0.0597 0.034 0.3338
Loa Loa (eye worm) AGC/AKT protein kinase 0.0761 0.0499 0.0484
Echinococcus granulosus tyrosine protein kinase Lyn 0.1308 0.1027 0.1013
Loa Loa (eye worm) TK protein kinase 0.0261 0.0016 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.0339 0.0091 0.0091
Brugia malayi Protein kinase domain containing protein 0.0623 0.0365 0.035
Loa Loa (eye worm) CAMK/PKD protein kinase 0.113 0.0855 0.0841
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0407 0.0157 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0812 0.0548 0.0548
Toxoplasma gondii protein kinase 0.0261 0.0016 0.0006
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1226 0.0947 0.0933
Brugia malayi cyclin-dependent kinase 9 0.0425 0.0175 0.016
Giardia lamblia Kinase, CMGC CK2 0.026 0.0016 0.0147
Loa Loa (eye worm) hypothetical protein 0.1111 0.0836 0.0822
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0261 0.0016 0.0016
Plasmodium falciparum serine/threonine protein kinase, putative 0.0661 0.0402 0.4147
Trypanosoma brucei Casein kinase II 0.026 0.0016 0.0016
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0812 0.0548 0.0548
Brugia malayi Protein kinase domain containing protein 0.2502 0.2178 0.2166
Schistosoma mansoni serine/threonine protein kinase 0.0389 0.014 0.0354
Echinococcus multilocularis TGF beta receptor type 1 0.0929 0.0661 0.0661
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0295 0.0049 0.0033
Echinococcus granulosus cGMP dependent protein kinase 0.0296 0.005 0.0035
Echinococcus granulosus neuroglian 0.0857 0.0592 0.0577
Schistosoma mansoni vam6/vps39 related 0.0712 0.0452 0.1243
Echinococcus multilocularis roundabout 2 0.0989 0.0719 0.0719
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0659 0.04 0.04
Schistosoma mansoni protein kinase 0.0357 0.0109 0.0265
Brugia malayi Protein kinase domain containing protein 0.0488 0.0235 0.022
Brugia malayi Protein kinase domain containing protein 0.0436 0.0185 0.017
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1487 0.12 0.12
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0261 0.0016 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0301 0.0055 0.0535
Echinococcus granulosus N chimaerin 0.0388 0.0139 0.0124
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0595 0.0339 0.0339
Trypanosoma brucei Pseudokinase, putative 0.0261 0.0016 0.0016
Brugia malayi RhoGAP domain containing protein 0.0388 0.0139 0.0124
Echinococcus multilocularis dual specificity protein kinase clk2 0.1122 0.0847 0.0847
Echinococcus multilocularis titin 0.0425 0.0175 0.0175
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0712 0.0452 0.0452
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0994 0.0724 0.0709
Giardia lamblia Kinase, STE STE20 0.0407 0.0157 0.1487
Trichomonas vaginalis protein tyrosine kinase, putative 0.0261 0.0016 0.0153
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0459 0.0208 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0016 0.0152
Echinococcus multilocularis serine:threonine protein kinase 3 0.0423 0.0173 0.0173
Plasmodium falciparum protein kinase, putative 0.0261 0.0016 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0528 0.0274 0.0259
Onchocerca volvulus Tyrosine kinase homolog 0.3114 0.2769 0.4029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Toxoplasma gondii histone kinase SNF1, putative 0.0388 0.0139 0.1323
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus granulosus cyclin dependent kinase 0.0507 0.0253 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0812 0.0548 0.1518
Echinococcus granulosus STE20 serine:threonine protein kinase 0.067 0.0411 0.0396
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0261 0.0016 0.0001
Brugia malayi Protein kinase domain containing protein 0.0492 0.024 0.0225
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Loa Loa (eye worm) hypothetical protein 0.0592 0.0336 0.0321
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0548
Echinococcus multilocularis beta adrenergic receptor kinase 0.0336 0.0088 0.0088
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0803 0.054 0.054
Brugia malayi Fibronectin type III domain containing protein 0.0695 0.0435 0.042
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Brugia malayi Immunoglobulin I-set domain containing protein 0.0331 0.0084 0.0068
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1118 0.0843 0.0843
Schistosoma mansoni serine/threonine kinase 0.0486 0.0234 0.0622
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Onchocerca volvulus 0.094 0.0672 0.0959
Entamoeba histolytica protein kinase, putative 0.0587 0.0331 0.3242
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Echinococcus multilocularis natriuretic peptide receptor 1 0.0261 0.0016 0.0016
Entamoeba histolytica protein kinase, putative 0.0761 0.0499 0.4894
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0261 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.005 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0049 0.0033
Brugia malayi Protein kinase domain containing protein 0.0475 0.0223 0.0208
Echinococcus granulosus roundabout 2 0.0331 0.0084 0.0068
Plasmodium falciparum protein kinase 5 0.0507 0.0253 0.2553
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Brugia malayi serine/threonine kinase 12 0.0661 0.0402 0.0387
Echinococcus multilocularis casein kinase I alpha 0.0659 0.04 0.04
Trypanosoma cruzi casein kinase, putative 0.0659 0.04 0.04
Echinococcus granulosus insulin receptor 0.1439 0.1153 0.114
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Plasmodium falciparum NIMA related kinase 1 0.0298 0.0052 0.0388
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0595 0.0339 0.0324
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1118 0.0843 0.0843
Echinococcus multilocularis Immunoglobulin 0.0659 0.04 0.04
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Entamoeba histolytica hypothetical protein 0.0264 0.0019 0.0188
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2897 0.256 0.2548
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1122 0.0847 0.0847
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0016 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Loa Loa (eye worm) hypothetical protein 0.1516 0.1228 0.1214
Trichomonas vaginalis CMGC family protein kinase 0.0507 0.0253 0.2401
Echinococcus granulosus serine:threonine protein kinase 3 0.0423 0.0173 0.0158
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0587 0.0331 0.0331
Entamoeba histolytica p21-activated kinase 0.0453 0.0201 0.1974
Loa Loa (eye worm) hypothetical protein 0.457 0.4174 0.4165
Onchocerca volvulus 0.0385 0.0136 0.0176
Plasmodium falciparum cGMP-dependent protein kinase 0.0296 0.005 0.0372
Echinococcus multilocularis tyrosine protein kinase Abl 0.14 0.1116 0.1116
Onchocerca volvulus 0.0488 0.0235 0.0321
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0261 0.0016 0.0016
Echinococcus multilocularis ephrin type A receptor 4 A 0.0327 0.008 0.008
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0367 0.0118 0.0103
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0261 0.0016 0.0016
Loa Loa (eye worm) AGC/PKA protein kinase 0.0812 0.0548 0.0533
Plasmodium falciparum casein kinase 1 0.0659 0.04 0.4127
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Schistosoma mansoni protein kinase 0.0261 0.0016 0.0002
Echinococcus multilocularis N chimaerin 0.0388 0.0139 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Echinococcus multilocularis lachesin 0.0295 0.0049 0.0049
Trypanosoma brucei cdc2-related kinase 3 0.0507 0.0253 0.0253
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 1.0608 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0858 0.0593 0.581
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0659 0.04 0.04
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1057 0.0784 0.077
Entamoeba histolytica protein kinase, putative 0.0595 0.0339 0.3325
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1226 0.0947 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.067 0.0411 0.1128
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.0016 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0483 0.023 0.0215
Echinococcus granulosus casein kinase I alpha 0.0659 0.04 0.0385
Echinococcus multilocularis tyrosine kinase 0.0488 0.0235 0.0235
Echinococcus granulosus dual specificity 0.1301 0.102 0.1006
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0261 0.0016 0.0002
Trypanosoma brucei polo-like protein kinase 0.0339 0.0091 0.0091
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0111 0.105
Loa Loa (eye worm) hypothetical protein 0.0812 0.0548 0.0533
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.0016 0.0001
Echinococcus granulosus defective proboscis extension response 0.0659 0.04 0.0385
Entamoeba histolytica ankyrin repeat protein 0.0261 0.0016 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0016 0.0147
Schistosoma mansoni vav2 0.0434 0.0184 0.0479
Plasmodium falciparum protein kinase, putative 0.0451 0.02 0.1976
Echinococcus granulosus roundabout 2 0.0989 0.0719 0.0705
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0016 0.0158
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0319 0.0072 0.0057
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0812 0.0548 0.0548
Brugia malayi Protein kinase domain containing protein 0.0587 0.0331 0.0316
Echinococcus granulosus calcium dependent protein kinase 0.0405 0.0156 0.014
Brugia malayi Protein kinase domain containing protein 0.0261 0.0016 0.0001
Brugia malayi Variant SH3 domain containing protein 0.0274 0.0029 0.0014
Echinococcus multilocularis 0.0932 0.0664 0.0664
Brugia malayi integrin-linked kinase 0.0261 0.0016 0.0001
Trypanosoma cruzi Protein kinase B 0.0365 0.0117 0.0117
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0331 0.0084 0.0084
Schistosoma mansoni nephrin 0.0893 0.0626 0.174
Echinococcus multilocularis activin receptor type 0.4224 0.3841 0.3841
Echinococcus granulosus serine:threonine protein kinase N2 0.1195 0.0918 0.0904
Entamoeba histolytica ankyrin repeat protein 0.0261 0.0016 0.0158
Brugia malayi Sex muscle abnormal protein 5 0.0405 0.0155 0.014
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0913 0.0646 0.0631
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0301 0.0055 0.0039
Schistosoma mansoni tyrosine kinase 0.1487 0.12 0.3374
Echinococcus granulosus tyrosine protein kinase Fyn 0.1118 0.0843 0.0829
Echinococcus multilocularis c src tyrosine kinase 0.0666 0.0407 0.0407
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.0016 0.0001
Echinococcus granulosus fibroblast growth factor receptor 4 0.1487 0.12 0.1186
Schistosoma mansoni tyrosine kinase 0.0261 0.0016 0.0002
Echinococcus granulosus serine threonine protein kinase nrc 0.0319 0.0072 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0365 0.0117 0.0288
Brugia malayi bone morphogenetic protein type 1 receptor 0.1 0.0729 0.0715
Schistosoma mansoni kinase 0.0425 0.0175 0.0454
Brugia malayi Temporarily assigned gene name protein 59 0.0712 0.0452 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0761 0.0499 0.473
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0661 0.0402 0.394
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2502 0.2178 0.2166
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0301 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0261 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0349 0.0101 0.0086
Schistosoma mansoni protein kinase 0.0451 0.02 0.0525
Schistosoma mansoni tyrosine kinase 0.1058 0.0785 0.2193
Entamoeba histolytica protein kinase, putative 0.0761 0.0499 0.4894
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0969 0.0699 0.0685
Echinococcus granulosus cGMP dependent protein kinase 1 0.0296 0.005 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.0253 0.0678
Loa Loa (eye worm) hypothetical protein 0.0295 0.0049 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0261 0.0016 0.0016
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0715 0.0455 0.044
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0812 0.0548 0.0548
Brugia malayi hypothetical protein 0.0488 0.0235 0.022
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0507 0.0253 0.2553
Echinococcus granulosus mitogen activated protein kinase 11 1.0608 1 1
Brugia malayi Protein kinase domain 0.0407 0.0157 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0261 0.0016 0.0153
Entamoeba histolytica protein kinase, putative 0.1301 0.102 1
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0812 0.0548 0.5717
Trichomonas vaginalis CAMK family protein kinase 0.0388 0.0139 0.1315
Echinococcus granulosus dual specificity mitogen activated protein 0.1338 0.1055 0.1041
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 1.0608 1 1
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1081 0.0808 0.0794
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1453 0.1167 0.1153
Schistosoma mansoni tyrosine kinase 0.0853 0.0587 0.163
Trichomonas vaginalis CAMK family protein kinase 0.038 0.0131 0.1242
Brugia malayi Protein kinase domain containing protein 0.0488 0.0235 0.022
Plasmodium vivax protein kinase Crk2 0.0507 0.0253 0.2553
Entamoeba histolytica cysteine surface protein, putative 0.0261 0.0016 0.0158
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1301 0.102 0.102
Loa Loa (eye worm) hypothetical protein 0.0754 0.0493 0.0478
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2328 0.2011 0.2011
Entamoeba histolytica protein kinase, putative 0.0261 0.0016 0.0158
Echinococcus granulosus cyclin dependent kinase 1 0.0507 0.0253 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.1226 0.0947 0.8976
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1122 0.0847 0.0847
Schistosoma mansoni serine/threonine protein kinase 0.0812 0.0548 0.1518
Brugia malayi Tyrosine-protein kinase abl-1 0.1187 0.091 0.0895
Echinococcus granulosus titin 0.0425 0.0175 0.0159
Brugia malayi Variant SH3 domain containing protein 0.0405 0.0155 0.014
Plasmodium falciparum calcium-dependent protein kinase 1 0.0595 0.0339 0.3474
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0331 0.0084 0.0068
Echinococcus multilocularis raf serine:threonine protein kinase 0.0422 0.0172 0.0172
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0566 0.0311 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0812 0.0548 0.1518
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.0016 0.0158
Brugia malayi Fes/CIP4 homology domain containing protein 0.0844 0.0579 0.0564
Echinococcus granulosus neuroglian 0.0331 0.0084 0.0068

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.003 uM Inhibition of CDK2 ChEMBL. 18996007
IC50 (functional) = 0.003 uM Antiproliferative activity against human LoVo cells assessed as inhibition of BrdU incorporation after 48 hrs ChEMBL. 18996007
IC50 (binding) = 0.029 uM Inhibition of CDK1 ChEMBL. 18996007

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 18996007

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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