Detailed information for compound 971767

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 434.527 | Formula: C26H30N2O4
  • H donors: 4 H acceptors: 3 LogP: 1.56 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1cc(ccc1C(=O)O)c1ccc(cc1)CCNC[C@@H](c1ccc(cc1)N)O)C
  • InChi: 1S/C26H30N2O4/c1-17(2)32-25-15-21(9-12-23(25)26(30)31)19-5-3-18(4-6-19)13-14-28-16-24(29)20-7-10-22(27)11-8-20/h3-12,15,17,24,28-29H,13-14,16,27H2,1-2H3,(H,30,31)/t24-/m0/s1
  • InChiKey: AUGGMUVNPWIEHR-DEOSSOPVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adrenoceptor beta 1 Starlite/ChEMBL References
Homo sapiens adrenoceptor beta 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis jumonji domain containing protein 0.0504 0.1208 0.207
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0033 0.0029 0.0048
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0768 0.1872 0.3208
Echinococcus granulosus caspase 8 0.0024 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Loa Loa (eye worm) hypothetical protein 0.0078 0.0142 0.0241
Schistosoma mansoni sodium/chloride dependent transporter 0.0155 0.0334 0.0572
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0603 0.1457 0.5023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0142 0.0243
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0096 0.0092
Schistosoma mansoni biogenic amine (5HT) receptor 0.0152 0.0328 0.0562
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0061 0.0099 0.0169
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0154 0.0331 0.0565
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Schistosoma mansoni hypothetical protein 0.0056 0.0085 0.0146
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0313 0.073 0.0725
Loa Loa (eye worm) jmjC domain-containing protein 0.0202 0.0452 0.0773
Leishmania major hypothetical protein, conserved 0.0026 0.001 0.0073
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0152 0.0328 0.056
Plasmodium falciparum transporter, putative 0.0154 0.0331 0.1127
Loa Loa (eye worm) jmjC domain-containing protein 0.0768 0.1871 0.3205
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0043 0.0054 0.0678
Schistosoma mansoni alpha-1 adrenergic receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0096
Loa Loa (eye worm) thioredoxin reductase 0.0279 0.0644 0.1102
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1177 0.2895 1
Echinococcus granulosus leukotriene A 4 hydrolase 0.0101 0.0199 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Giardia lamblia Synaptic glycoprotein SC2 0.0061 0.0099 0.1053
Mycobacterium ulcerans glutamate synthase subunit beta 0.0026 0.001 0.0018
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0202 0.0452 0.6191
Loa Loa (eye worm) pre-B cell enhancing factor 0.0485 0.1162 0.199
Echinococcus multilocularis G protein coupled receptor 139 0.0152 0.0328 0.056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0051 0.0087
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0313 0.073 0.0725
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Echinococcus multilocularis apoptotic protease activating factor 1 0.0055 0.0084 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0018 0.0231
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0051 0.0073 0.0237
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0051 0.0087
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Brugia malayi nuclear receptor RXR 0.0022 0.0001 0.0003
Loa Loa (eye worm) matrixin family protein 0.0099 0.0192 0.0328
Echinococcus granulosus alpha 1A adrenergic receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) heat shock protein 75 0.0078 0.0141 0.024
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0152 0.0328 0.056
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0029 0.0018 0.0082
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.001 0.0015
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0051 0.0155
Schistosoma mansoni biogenic amine (5HT) receptor 0.2349 0.5834 1
Schistosoma mansoni glutamate receptor NMDA 0.0084 0.0157 0.0269
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.001 0.0018
Echinococcus granulosus allatostatin A receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) endoplasmin 0.0117 0.024 0.0409
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0152 0.0328 0.0562
Brugia malayi Serine/threonine-protein kinase Pim-3 0.013 0.0272 0.0831
Schistosoma mansoni rab6-interacting 0.0153 0.0329 0.0564
Schistosoma mansoni heat shock protein 0.0078 0.0141 0.0242
Mycobacterium leprae conserved hypothetical protein 0.0051 0.0073 0.0237
Brugia malayi dihydrofolate reductase family protein 0.0028 0.0015 0.0046
Onchocerca volvulus 0.0152 0.0328 0.1479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0051 0.0085
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.003 0.002 0.0266
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0026 0.001 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0073 0.0129 0.0431
Treponema pallidum sodium- and chloride- dependent transporter 0.0905 0.2215 0.7643
Trichomonas vaginalis heat shock protein, putative 0.011 0.0222 0.0217
Echinococcus granulosus tar DNA binding protein 0.0033 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.0118 0.0241 0.0412
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Brugia malayi Thioredoxin reductase 0.0279 0.0644 0.1969
Loa Loa (eye worm) G-protein coupled receptor 0.0152 0.0328 0.056
Echinococcus granulosus sodium channel protein 0.0043 0.0054 0.009
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0181 0.0399 0.122
Loa Loa (eye worm) RNA binding protein 0.0033 0.0029 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Echinococcus granulosus sodium and chloride dependent glycine 0.0154 0.0331 0.0565
Echinococcus granulosus lipoxygenase domain containing protein 0.0153 0.0329 0.0563
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0001 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Leishmania major heat shock protein, putative 0.0078 0.0141 0.1884
Onchocerca volvulus Matrix metalloproteinase homolog 0.0099 0.0192 0.0869
Echinococcus granulosus fmrfamide receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) doublecortin family protein 0.0153 0.0329 0.0563
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0051 0.0085
Brugia malayi AF-10 protein 0.0118 0.0242 0.0741
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0051 0.0155
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.0166
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.009 0.0171 0.1022
Loa Loa (eye worm) CAMK/PIM protein kinase 0.013 0.0272 0.0464
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0321 0.0548
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.001 0.0017
Onchocerca volvulus 0.0026 0.001 0.0044
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0056 0.0085 0.0144
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0061 0.0099 0.0324
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Brugia malayi hypothetical protein 0.0022 0.0001 0.0003
Echinococcus multilocularis prolyl endopeptidase 0.0062 0.0102 0.0172
Trypanosoma cruzi heat shock protein 90, putative 0.0049 0.0069 0.093
Plasmodium vivax ferrodoxin reductase, putative 0.0026 0.001 0.0017
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0152 0.0328 0.1002
Onchocerca volvulus 0.0152 0.0328 0.1479
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0321 0.0548
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.011 0.0222 0.1334
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0028 0.0015 0.0064
Trypanosoma brucei protein kinase, putative 0.006 0.0096 0.1262
Echinococcus multilocularis GPCR, family 2 0.0037 0.0039 0.0065
Schistosoma mansoni heat shock protein 0.0117 0.024 0.0411
Echinococcus granulosus glutamate receptor subunit protein glur 0.0056 0.0086 0.0146
Plasmodium vivax heat shock protein 86, putative 0.0117 0.024 0.0813
Echinococcus granulosus dro:myosuppressin receptor 0.0152 0.0328 0.056
Echinococcus granulosus glutamate receptor 4 0.003 0.002 0.0033
Mycobacterium tuberculosis Probable dehydrogenase 0.0603 0.1457 0.8909
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0362 0.0853 0.1462
Toxoplasma gondii PHD-finger domain-containing protein 0.0362 0.0853 0.2934
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0096 0.131
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0024 0.0006 0.0008
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0025 0.0009 0.0013
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0114 0.0232 0.0395
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0096 0.0092
Toxoplasma gondii PHD-finger domain-containing protein 0.0118 0.0242 0.0821
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Brugia malayi ecdysteroid receptor 0.0042 0.0051 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0142 0.0243
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0051 0.0085
Entamoeba histolytica thioredoxin reductase, putative 0.0026 0.001 0.0073
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0051 0.0073 0.0421
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0152 0.0328 0.056
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0051 0.0073 0.0236
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0024 0.0006 0.0002
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0321 0.0548
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1177 0.2895 1
Schistosoma mansoni sodium-dependent amino acid transporter 0.0154 0.0331 0.0567
Echinococcus multilocularis sodium and chloride dependent glycine 0.0154 0.0331 0.0565
Onchocerca volvulus 0.0057 0.0089 0.0402
Toxoplasma gondii hypothetical protein 0.0034 0.0031 0.0092
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0152 0.0328 0.056
Echinococcus multilocularis heat shock protein 0.0117 0.024 0.0409
Echinococcus granulosus biogenic amine 5HT receptor 0.2349 0.5834 1
Brugia malayi Glutamate receptor 2 precursor 0.0101 0.0198 0.0606
Leishmania major hypothetical protein, conserved 0.0026 0.001 0.0073
Trypanosoma cruzi polo-like protein kinase, putative 0.0052 0.0076 0.1033
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0096 0.0163
Echinococcus multilocularis thioredoxin glutathione reductase 0.028 0.0648 0.111
Onchocerca volvulus Serine\/threonine kinase homolog 0.0052 0.0076 0.0344
Loa Loa (eye worm) hypothetical protein 0.0065 0.0107 0.0182
Echinococcus granulosus glutamate receptor 1 0.003 0.002 0.0033
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0079 0.0133
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0039 0.012
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.2293
Schistosoma mansoni neuropeptide F-like receptor 0.0152 0.0328 0.0562
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0142
Schistosoma mansoni lamin 0.0071 0.0123 0.0211
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0152 0.0328 0.1479
Brugia malayi latrophilin 2 splice variant baaae 0.0081 0.0148 0.0452
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0026 0.001 0.0015
Trypanosoma brucei oligopeptidase b 0.0025 0.0008 0.0037
Echinococcus multilocularis sodium and chloride dependent glycine 0.0154 0.0331 0.0565
Mycobacterium ulcerans NADH dehydrogenase 0.0026 0.001 0.0018
Brugia malayi TAR-binding protein 0.0033 0.0029 0.0089
Echinococcus granulosus serotonin transporter 0.0905 0.2215 0.3795
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.001 0.0017
Echinococcus granulosus jumonji domain containing protein 0.0504 0.1208 0.207
Mycobacterium ulcerans thymidylate synthase 0.0068 0.0116 0.0385
Brugia malayi RNA recognition motif domain containing protein 0.0033 0.0029 0.0089
Schistosoma mansoni gamma-secretase subunit aph-1 0.0096 0.0187 0.0321
Trypanosoma cruzi prolyl endopeptidase 0.0062 0.0102 0.1382
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0152 0.0328 0.056
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0061 0.0099 0.0324
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0026 0.001 0.0018
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0024 0.0006 0.0004
Echinococcus granulosus heat shock protein 90 0.01 0.0197 0.0336
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.1177 0.2895 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0024 0.0006 0.001
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0096 0.1028
Brugia malayi Pre-SET motif family protein 0.0078 0.0142 0.0434
Loa Loa (eye worm) glutaminase 0.0157 0.034 0.0581
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0006 0.0008
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0026 0.0011 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0273 0.063 0.2166
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0096 0.0187 0.0319
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0026 0.001 0.0017
Brugia malayi hypothetical protein 0.0032 0.0027 0.0081
Echinococcus multilocularis L aminoadipate semialdehyde 0.0181 0.0399 0.0682
Giardia lamblia Kinase, PLK 0.0052 0.0076 0.0789
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0051 0.0155
Mycobacterium ulcerans monoxygenase 0.0026 0.001 0.0018
Trichomonas vaginalis apoptosis inducing factor, putative 0.0026 0.001 0.0005
Echinococcus granulosus GPCR family 2 0.0037 0.0039 0.0065
Toxoplasma gondii PHD-finger domain-containing protein 0.0362 0.0853 0.2934
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Mycobacterium tuberculosis Probable oxidoreductase 0.0674 0.1634 1
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0026 0.001 0.0018
Toxoplasma gondii heat shock protein 75, putative 0.0078 0.0141 0.0471
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0006
Leishmania major DNA polymerase eta, putative 0.0054 0.008 0.1036
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Trypanosoma brucei Heat shock protein 83, putative 0.0117 0.024 0.3242
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.001 0.012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0152 0.0328 0.056
Brugia malayi ImpB/MucB/SamB family protein 0.0029 0.0018 0.0054
Echinococcus granulosus endoplasmin 0.011 0.0222 0.0378
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0025 0.0009 0.0015
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0097 0.0187 0.2518
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0062 0.0102 0.0174
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.009 0.0171 0.1022
Echinococcus multilocularis g-protein coupled receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) solute carrier family 6 member 4 0.0905 0.2215 0.3795
Mycobacterium ulcerans hypothetical protein 0.0112 0.0226 0.0766
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Schistosoma mansoni hypothetical protein 0.0308 0.0718 0.123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0152 0.0328 0.0562
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0603 0.1457 0.8909
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0096 0.0185 0.0624
Loa Loa (eye worm) hypothetical protein 0.2349 0.5834 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Echinococcus multilocularis serotonin receptor 0.2349 0.5834 1
Plasmodium falciparum heat shock protein 90, putative 0.0068 0.0117 0.0387
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0032 0.0027 0.0351
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0051 0.0085
Schistosoma mansoni neuropeptide receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) programmed cell death 8 0.0026 0.001 0.0015
Schistosoma mansoni hypothetical protein 0.0026 0.001 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0026 0.0012 0.0007
Schistosoma mansoni opsin-like receptor 0.0152 0.0328 0.0562
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0025 0.0009 0.0026
Onchocerca volvulus 0.0055 0.0084 0.0379
Trypanosoma brucei prolyl oligopeptidase, putative 0.0025 0.0008 0.0037
Onchocerca volvulus 0.0152 0.0328 0.1479
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0152 0.0328 0.056
Onchocerca volvulus Alhambra homolog 0.0362 0.0853 0.3851
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0603 0.1457 0.8909
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2523
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.001 0.0073
Onchocerca volvulus 0.0153 0.0329 0.1487
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.008 0.026
Schistosoma mansoni jumonji domain containing protein 0.1082 0.2658 0.4556
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0546 0.1314 0.2251
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Brugia malayi Matrixin family protein 0.0044 0.0057 0.0174
Leishmania major hypothetical protein, conserved 0.0026 0.001 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0272 0.0466
Brugia malayi Intermediate filament tail domain containing protein 0.0071 0.0123 0.0376
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.001 0.0015
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0043 0.0054 0.009
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.1326 0.3269 0.5602
Brugia malayi MAP kinase sur-1 0.006 0.0096 0.0295
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0067
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0101 0.0199 0.0341
Onchocerca volvulus Huntingtin homolog 0.0065 0.0107 0.0485
Trypanosoma cruzi heat shock protein 85, putative 0.01 0.0197 0.2695
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0154 0.0331 0.0567
Echinococcus granulosus neuropeptide receptor 0.0152 0.0328 0.056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0087 0.0163 0.0277
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.001 0.0005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0029 0.0018 0.0031
Trypanosoma cruzi Heat shock protein 83, putative 0.0117 0.024 0.3279
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Plasmodium falciparum heat shock protein 90, putative 0.0445 0.1061 0.3655
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0052 0.0076 0.0129
Giardia lamblia NADH oxidase lateral transfer candidate 0.0097 0.0187 0.2108
Brugia malayi hypothetical protein 0.0065 0.0107 0.0329
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0026 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0009
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Onchocerca volvulus 0.0071 0.0123 0.0554
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0152 0.0328 0.056
Entamoeba histolytica hypothetical protein 0.0056 0.0085 0.1109
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0026 0.001 0.0066
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0096 0.0317
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0051 0.0085
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0321 0.0548
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0202 0.0452 0.617
Mycobacterium tuberculosis Probable reductase 0.0603 0.1457 0.8909
Mycobacterium ulcerans aldehyde dehydrogenase 0.0273 0.063 0.2166
Trichomonas vaginalis set domain proteins, putative 0.0621 0.1503 0.1499
Trypanosoma cruzi Aph-1 protein, putative 0.0038 0.004 0.0531
Trypanosoma brucei prolyl endopeptidase 0.0062 0.0102 0.1335
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0039 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0087 0.0163 0.0277
Schistosoma mansoni hypothetical protein 0.0733 0.1782 0.3054
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0384 0.0909 0.1557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Echinococcus granulosus thioredoxin glutathione reductase 0.028 0.0648 0.111
Trypanosoma cruzi metacaspase, putative 0.0024 0.0005 0.0054
Echinococcus granulosus histone lysine methyltransferase setb 0.0078 0.0142 0.0241
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0018 0.0178
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0202 0.0452 0.1547
Plasmodium falciparum phd finger protein, putative 0.0362 0.0853 0.2934
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.027 0.0621 0.1065
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.001 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.1326 0.3269 0.5602
Schistosoma mansoni hypothetical protein 0.0063 0.0103 0.0177
Brugia malayi larval opioid receptor 0.0152 0.0328 0.1002
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Plasmodium vivax heat shock protein, putative 0.0445 0.1061 0.3655
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0026 0.001 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0025 0.0009 0.0013
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0073 0.0129 0.0431
Brugia malayi Cell death protein 3 precursor 0.0079 0.0143 0.0438
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0097 0.0187 0.0319
Loa Loa (eye worm) hypothetical protein 0.0313 0.073 0.1249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Brugia malayi N-terminal motif family protein 0.0084 0.0157 0.048
Trypanosoma cruzi heat shock protein 90, putative 0.0117 0.024 0.3279
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0051 0.0087
Brugia malayi sulfakinin receptor protein 0.0152 0.0328 0.1002
Loa Loa (eye worm) hypothetical protein 0.0202 0.0452 0.0773
Toxoplasma gondii TIM10 family protein, putative 0.0025 0.0009 0.0013
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0118 0.0242 0.3272
Brugia malayi CXXC zinc finger family protein 0.0234 0.0533 0.163
Schistosoma mansoni disulfide oxidoreductase 0.0026 0.001 0.0017
Entamoeba histolytica hypothetical protein 0.0056 0.0085 0.1109
Brugia malayi Matrixin family protein 0.0044 0.0057 0.0174
Schistosoma mansoni hypothetical protein 0.0055 0.0084 0.0144
Echinococcus multilocularis dihydrofolate reductase 0.0028 0.0015 0.0024
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0051 0.0085
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0101 0.0197 0.2697
Loa Loa (eye worm) hypothetical protein 0.0529 0.1272 0.2179
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0273 0.063 0.1079
Echinococcus multilocularis fmrfamide receptor 0.0152 0.0328 0.056
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.001 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0051 0.0155
Echinococcus multilocularis somatostatin receptor 0.0152 0.0328 0.056
Brugia malayi jmjC domain containing protein 0.0202 0.0452 0.1383
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0051 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Echinococcus multilocularis musashi 0.0071 0.0123 0.0209
Echinococcus granulosus PHD finger protein rhinoceros 0.0362 0.0853 0.1461
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0087 0.0163 0.0277
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Schistosoma mansoni neuropeptide f receptor 76f 0.0152 0.0328 0.0562
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0154 0.0331 0.0565
Plasmodium falciparum amino acid transporter, putative 0.0154 0.0331 0.1127
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0061 0.0099 0.0167
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0202 0.0452 0.0775
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0026 0.001 0.0005
Onchocerca volvulus 0.0152 0.0328 0.1479
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0096 0.1268
Loa Loa (eye worm) hypothetical protein 0.0034 0.0031 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0152 0.0328 0.056
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0084 0.0157 0.0708
Plasmodium vivax endoplasmin, putative 0.0117 0.024 0.0813
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0097 0.0187 0.0632
Plasmodium falciparum plasmepsin II 0.0024 0.0006 0.0004
Leishmania major cathepsin L-like protease 0.0028 0.0016 0.016
Entamoeba histolytica serine/threonine protein kinase, putative 0.0052 0.0076 0.099
Echinococcus granulosus g protein coupled receptor 0.0152 0.0328 0.056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0152 0.0328 0.056
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0068 0.0116 0.0385
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0075 0.0135 0.0229
Schistosoma mansoni glutamate receptor kainate 0.0136 0.0287 0.0492
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0152 0.0328 0.056
Brugia malayi MH2 domain containing protein 0.0179 0.0395 0.121
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus multilocularis peregrin 0.0362 0.0853 0.1461
Schistosoma mansoni phosphatidylserine receptor 0.0202 0.0452 0.0775
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0051 0.0087
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0011 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0029 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0152 0.0328 0.056
Trypanosoma cruzi polo-like protein kinase, putative 0.0052 0.0076 0.1033
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.001 0.0015
Onchocerca volvulus 0.0154 0.0331 0.1493
Plasmodium vivax glutathione reductase, putative 0.0279 0.0644 0.221
Echinococcus granulosus caspase 2 0.0079 0.0143 0.0244
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0273 0.063 0.3841
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0152 0.0328 0.056
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0154 0.0331 0.0565
Echinococcus granulosus sodium and chloride dependent glycine 0.0154 0.0331 0.0565
Leishmania major cathepsin L-like protease 0.0028 0.0016 0.016
Echinococcus multilocularis synaptic glycoprotein sc2 0.0061 0.0099 0.0167
Plasmodium falciparum thioredoxin reductase 0.0279 0.0644 0.221
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0025 0.0008 0.0091
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0026 0.001 0.0015
Schistosoma mansoni cpg binding protein 0.0234 0.0533 0.0913
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1012
Trypanosoma cruzi heat shock protein 85, putative 0.0117 0.024 0.3279
Schistosoma mansoni jumonji/arid domain-containing protein 0.069 0.1675 0.2871
Trypanosoma cruzi cruzipain precursor, putative 0.0028 0.0016 0.0207
Echinococcus granulosus g protein coupled receptor 0.0152 0.0328 0.056
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0029 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0087 0.0163 0.0279
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0097 0.0187 0.1123
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0034 0.0031 0.0051
Onchocerca volvulus 0.0068 0.0116 0.0523
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0152 0.0328 0.0562
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0026 0.001 0.0018
Brugia malayi PHD-finger family protein 0.0362 0.0853 0.261
Loa Loa (eye worm) jmjC domain-containing protein 0.0748 0.1819 0.3117
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.2297
Echinococcus multilocularis orexin receptor type 2 0.0152 0.0328 0.056
Trypanosoma cruzi metacaspase, putative 0.0024 0.0005 0.0054
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0096 0.0163
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0279 0.0645 0.1104
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0051 0.0073 0.0237
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.001 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0025 0.0008 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0051 0.0085
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0313 0.073 1
Trichomonas vaginalis heat shock protein, putative 0.011 0.0222 0.0217
Brugia malayi Serotonin receptor 0.0152 0.0328 0.1002
Trypanosoma brucei unspecified product 0.0029 0.0018 0.0178
Schistosoma mansoni jumonji/arid domain-containing protein 0.069 0.1675 0.2871
Echinococcus multilocularis lipoxygenase domain containing protein 0.0153 0.0329 0.0563
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0051 0.0155
Brugia malayi neuropeptide F receptor 0.0152 0.0328 0.1002
Loa Loa (eye worm) TAR-binding protein 0.0033 0.0029 0.0048
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0154 0.0331 0.0567
Loa Loa (eye worm) serotonin transporter b 0.0905 0.2215 0.3795
Loa Loa (eye worm) hypothetical protein 0.2349 0.5834 1
Brugia malayi glutaminase DH11.1 0.0157 0.034 0.1041
Loa Loa (eye worm) thymidylate synthase 0.0068 0.0116 0.0197
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0096
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0603 0.1457 0.8909
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0146 0.0311 0.4257
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus dna polymerase eta 0.0054 0.008 0.0135
Giardia lamblia DINP protein human, muc B family 0.0029 0.0018 0.0096
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.001 0.012
Plasmodium falciparum plasmepsin VI 0.0024 0.0006 0.0004
Schistosoma mansoni glutamate receptor kainate 0.0071 0.0123 0.0211
Echinococcus multilocularis allatostatin A receptor 0.0152 0.0328 0.056
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0078 0.0141 0.024
Schistosoma mansoni amine GPCR 0.0152 0.0328 0.0562
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Toxoplasma gondii hypothetical protein 0.0154 0.0331 0.1127
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0152 0.0328 0.056
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Echinococcus granulosus tachykinin peptides receptor 99D 0.0152 0.0328 0.056
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0152 0.0328 0.056
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0051 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0051 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Echinococcus granulosus neuropeptide receptor A26 0.0152 0.0328 0.056
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0078 0.0142 0.0241
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0152 0.0328 0.056
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0051 0.0085
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0029 0.005
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0026 0.001 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0087 0.0163 0.0279
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0008
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0603 0.1458 0.8919
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0028 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus dihydrofolate reductase 0.0028 0.0015 0.0024
Brugia malayi jmjC domain containing protein 0.1326 0.3269 1
Chlamydia trachomatis dihydrofolate reductase 0.0028 0.0015 0.0018
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.013 0.0272 0.0464
Schistosoma mansoni growth hormone secretagogue receptor 0.0152 0.0328 0.0562
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2143 0.5317 0.9114
Leishmania major phosphopantetheinyl transferase-like protein 0.0051 0.0073 0.0945
Plasmodium vivax SET domain protein, putative 0.0078 0.0142 0.0474
Loa Loa (eye worm) hypothetical protein 0.0137 0.0289 0.0494
Brugia malayi Synaptic glycoprotein SC2 0.0061 0.0099 0.0301
Schistosoma mansoni sodium/chloride dependent transporter 0.0154 0.0331 0.0567
Loa Loa (eye worm) CAMK/PIM protein kinase 0.013 0.0272 0.0464
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0051 0.0155
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0024 0.0006 0.0008
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0097 0.0187 0.0616
Entamoeba histolytica heat shock protein 90, putative 0.0117 0.024 0.3246
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0152 0.0328 0.056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Loa Loa (eye worm) intermediate filament protein 0.0071 0.0123 0.0209
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0026 0.001 0.0018
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.003 0.0395
Trypanosoma cruzi metacaspase, putative 0.0024 0.0005 0.0054
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0052 0.0076 0.0129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0052 0.0076 0.099
Trypanosoma cruzi Aph-1 protein, putative 0.0038 0.004 0.0531
Plasmodium falciparum plasmepsin I 0.0024 0.0006 0.0004
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0603 0.1457 0.8909
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0068 0.0116 0.0198
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0212 0.0478 0.6545
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0096 0.0185 0.2488
Brugia malayi Matrixin family protein 0.0044 0.0057 0.0174
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0152 0.0328 0.056
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0057 0.0089 0.0152
Entamoeba histolytica heat shock protein 90, putative 0.0117 0.024 0.3246
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0097 0.0187 0.0633
Mycobacterium ulcerans short chain dehydrogenase 0.0192 0.0428 0.1464
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0674 0.1634 1
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0024 0.0006 0.0001
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0152 0.0328 0.056
Toxoplasma gondii PLU-1 family protein 0.0078 0.0142 0.0473
Echinococcus multilocularis g protein coupled receptor 0.0152 0.0328 0.056
Schistosoma mansoni glutamate receptor AMPA 0.0071 0.0123 0.0211
Brugia malayi GnHR receptor homolog 0.0152 0.0328 0.1002
Echinococcus granulosus phd:f box containing protein 0.0356 0.0837 0.1433
Brugia malayi Hsp90 protein 0.0078 0.0141 0.0432
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0905 0.2215 0.3797
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0068 0.0116 0.0683
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0096 0.0185 0.2529
Leishmania major NADH dehydrogenase, putative 0.0026 0.001 0.0073
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0039 0.0065
Echinococcus multilocularis caspase 8 0.0024 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Trypanosoma brucei heat shock protein 90, putative 0.0117 0.024 0.3242
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Toxoplasma gondii aldehyde dehydrogenase 0.0273 0.063 0.2164
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0096 0.0163
Loa Loa (eye worm) TYRA-2 protein 0.0152 0.0328 0.056
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0024 0.0005 0.0008
Brugia malayi Pre-SET motif family protein 0.0546 0.1314 0.402
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0051 0.0087
Mycobacterium leprae PROBABLE HYDROLASE 0.0054 0.0081 0.0265
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0096 0.0185 0.0624
Plasmodium falciparum JmjC domain-containing protein, putative 0.0242 0.0552 0.1892
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Plasmodium vivax heat shock protein 90, putative 0.0078 0.0141 0.0471
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0026 0.001 0.0015
Onchocerca volvulus 0.0057 0.0089 0.0402
Giardia lamblia Grp94/Hsp90 0.011 0.0222 0.2515
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.001 0.0018
Brugia malayi Cation transporter family protein 0.0057 0.0089 0.0272
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0024 0.0006 0.0002
Schistosoma mansoni adenoreceptor 0.0152 0.0328 0.0562
Brugia malayi Serotonin receptor 0.054 0.13 0.3977
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0069 0.012 0.0203
Leishmania major cathepsin L-like protease 0.0028 0.0016 0.016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.027 0.0621 0.1901
Echinococcus multilocularis lysine specific demethylase 5A 0.0671 0.1627 0.2788
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0078 0.0141 0.024
Schistosoma mansoni polycystin 1-related 0.0153 0.0329 0.0564
Mycobacterium ulcerans aldehyde dehydrogenase 0.0273 0.063 0.2166
Entamoeba histolytica hypothetical protein 0.0056 0.0085 0.1109
Trypanosoma brucei C-8 sterol isomerase, putative 0.0146 0.0311 0.4225
Brugia malayi AKH receptor 0.0152 0.0328 0.1002
Mycobacterium tuberculosis Probable peptidase 0.0025 0.0008 0.0019
Echinococcus granulosus neuropeptide FF receptor 2 0.0152 0.0328 0.056
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0026 0.001 0.0017
Trypanosoma brucei polo-like protein kinase 0.0052 0.0076 0.0984
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.01 0.0197 0.0336
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.008 0.1083
Echinococcus multilocularis dna polymerase eta 0.0054 0.008 0.0135
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0242 0.0821
Mycobacterium tuberculosis Hypothetical protein 0.0032 0.0027 0.0135
Brugia malayi Matrixin family protein 0.0107 0.0215 0.0657
Echinococcus granulosus cpg binding protein 0.0253 0.058 0.0993
Trypanosoma brucei Aph-1 protein, putative 0.0038 0.004 0.0479
Echinococcus granulosus caspase 0.0024 0.0005 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0018 0.0178
Echinococcus multilocularis microtubule associated protein 2 0.1446 0.3571 0.612
Schistosoma mansoni heat shock protein 0.0117 0.024 0.0411
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0071 0.0123 0.0209
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0026 0.0011 0.0017
Echinococcus multilocularis caspase 0.0024 0.0005 0.0006
Plasmodium vivax plasmepsin IV, putative 0.0024 0.0006 0.0004
Brugia malayi PHD-finger family protein 0.0137 0.0289 0.0885
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0061 0.0099 0.0324
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.001 0.0015
Schistosoma mansoni glutamate synthase 0.0026 0.001 0.0017
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0024 0.0006 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Echinococcus granulosus 7TM GPCR rhodopsin 0.0152 0.0328 0.056
Plasmodium vivax hypothetical protein, conserved 0.0154 0.0331 0.1127
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.001 0.012
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0054 0.0081 0.0248
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0026 0.001 0.0017
Echinococcus granulosus serotonin receptor 0.0152 0.0328 0.056
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0101 0.0197 0.2657
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0087 0.0163 0.0277
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0248 0.0566 0.1943
Echinococcus granulosus lysine specific demethylase 6a 0.0202 0.0452 0.0773
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Mycobacterium ulcerans dehydrogenase 0.0026 0.001 0.0018
Schistosoma mansoni biogenic amine receptor 0.0152 0.0328 0.0562
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0016 0.0207
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0026 0.001 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0097 0.0187 0.2518
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0018 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0273 0.063 0.1081
Loa Loa (eye worm) hypothetical protein 0.0065 0.0107 0.0182
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0152 0.0328 0.056
Onchocerca volvulus 0.0152 0.0328 0.1479
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0067
Brugia malayi Glutamate receptor 1 precursor 0.0101 0.0198 0.0606
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0008
Brugia malayi Dopamine receptor protein 2 0.0152 0.0328 0.1002
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0026 0.001 0.0073
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0097 0.0187 0.0633
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Plasmodium vivax multidomain scavenger receptor, putative 0.0153 0.0329 0.1122
Schistosoma mansoni protein phosphatase 2C 0.0202 0.0452 0.0775
Schistosoma mansoni neuropeptide F-like receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0118 0.0241 0.0412
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0051 0.0155
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0001 0.0003
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0026 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus multilocularis heat shock protein 90 0.01 0.0197 0.0336
Echinococcus granulosus lamin 0.0071 0.0123 0.0209
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0097 0.0187 0.0632
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0051 0.0073 0.0219
Echinococcus granulosus G protein coupled receptor 139 0.0152 0.0328 0.056
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0024 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0362 0.0853 0.1461
Loa Loa (eye worm) hypothetical protein 0.0181 0.0399 0.0682
Loa Loa (eye worm) hypothetical protein 0.0905 0.2215 0.3795
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0018 0.0231
Echinococcus multilocularis glutamate receptor 4 0.003 0.002 0.0033
Echinococcus granulosus intermediate filament protein 0.0071 0.0123 0.0209
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.013 0.0272 0.1227
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0152 0.0328 0.1002
Leishmania major hypothetical protein, conserved 0.0202 0.0452 0.6173
Brugia malayi heat shock protein 90 0.0117 0.024 0.0734
Onchocerca volvulus Matrilysin homolog 0.0044 0.0057 0.0257
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.001 0.0073
Echinococcus multilocularis endoplasmin 0.011 0.0222 0.0378
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0097 0.0187 0.2523
Onchocerca volvulus 0.0024 0.0004 0.002
Echinococcus multilocularis glutamate receptor 2 0.0088 0.0166 0.0283
Brugia malayi putative neuropeptide receptor NPR1 0.0152 0.0328 0.1002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0034 0.0031 0.0051
Onchocerca volvulus 0.0078 0.0142 0.064
Loa Loa (eye worm) hypothetical protein 0.0071 0.0123 0.0209
Brugia malayi cytoplasmic intermediate filament protein 0.0038 0.004 0.0124
Loa Loa (eye worm) melatonin receptor type 1A 0.0152 0.0328 0.056
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.011 0.0222 0.2997
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0099 0.0094
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0018 0.0046
Brugia malayi neuropeptide F receptor 0.0152 0.0328 0.1002
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0384 0.0909 0.1557
Brugia malayi serine/threonine-protein kinase plk-2 0.0052 0.0076 0.0233
Echinococcus granulosus tm gpcr rhodopsin 0.0152 0.0328 0.056
Schistosoma mansoni caspase-7 (C14 family) 0.0024 0.0005 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0152 0.0328 0.056
Schistosoma mansoni opsin-like receptor 0.0152 0.0328 0.0562
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.0565
Echinococcus multilocularis serotonin transporter 0.0905 0.2215 0.3795
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0039 0.0065
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0279 0.0644 0.3922
Trypanosoma cruzi heat shock protein, putative 0.0078 0.0141 0.1923
Echinococcus multilocularis dro:myosuppressin receptor 0.0152 0.0328 0.056
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0051 0.0073 0.0236
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0028 0.0015 0.0036
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0485 0.1162 0.199
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Trypanosoma brucei RNA helicase, putative 0.0308 0.0718 0.9834
Entamoeba histolytica hypothetical protein 0.0051 0.0073 0.0945
Plasmodium vivax aspartyl proteinase, putative 0.0024 0.0006 0.0004
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Schistosoma mansoni phd/f-box containing protein 0.0356 0.0837 0.1434
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0073 0.0129 0.0394
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.003 0.0086
Plasmodium falciparum ferrodoxin reductase-like protein 0.0026 0.001 0.0017
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.002 0.0266
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.001 0.0066
Plasmodium falciparum LCCL domain-containing protein 0.0153 0.0329 0.1122
Echinococcus multilocularis neuropeptide Y receptor 0.0152 0.0328 0.056
Trypanosoma cruzi heat shock protein 85, putative 0.0117 0.024 0.3279
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0026 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0154 0.0331 0.1113
Onchocerca volvulus 0.0181 0.0399 0.1801
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) hypothetical protein 0.0079 0.0143 0.0244
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0062 0.0102 0.0174
Brugia malayi thymidylate synthase 0.0068 0.0116 0.0354
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.001 0.0018
Schistosoma mansoni hypothetical protein 0.0026 0.0011 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.008 0.026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Brugia malayi Hemopexin family protein 0.0063 0.0103 0.0316
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0152 0.0328 0.0562
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.008 0.1031
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0054 0.0081 0.047
Brugia malayi intermediate filament protein 0.0071 0.0123 0.0376
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0026 0.001 0.0073
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0018 0.0231
Toxoplasma gondii NADPH-glutathione reductase 0.0097 0.0187 0.0632
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0051 0.0073 0.0236
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Schistosoma mansoni cpg binding protein 0.0253 0.058 0.0995
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0006 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0152 0.0328 0.056
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0212 0.0478 0.6545
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.001 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0202 0.0452 0.0775
Onchocerca volvulus 0.0152 0.0328 0.1479
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0026 0.001 0.0032
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0026 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0033
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0024 0.0006 0.0063
Brugia malayi G-protein coupled receptor 0.0152 0.0328 0.1002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0051 0.0085
Loa Loa (eye worm) hypothetical protein 0.0075 0.0132 0.0225
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0154 0.0331 0.0565
Plasmodium falciparum heat shock protein 90 0.0117 0.024 0.0813
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Plasmodium falciparum glutathione reductase 0.0279 0.0644 0.221
Loa Loa (eye worm) dihydrofolate reductase 0.0028 0.0015 0.0024
Echinococcus granulosus g protein coupled receptor 0.0152 0.0328 0.056
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0313 0.073 1
Schistosoma mansoni lipoxygenase 0.0768 0.1872 0.3209
Onchocerca volvulus Prolyl endopeptidase homolog 0.0062 0.0102 0.0459
Echinococcus granulosus microtubule associated protein 2 0.1446 0.3571 0.612
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0039 0.0065
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Brugia malayi Bromodomain containing protein 0.0362 0.0853 0.261
Echinococcus granulosus peregrin 0.0362 0.0853 0.1461
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0051 0.0085
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0061 0.0099 0.0324
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0905 0.2215 0.6776
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0071 0.0123 0.0377
Echinococcus multilocularis lipoxygenase domain containing protein 0.0153 0.0329 0.0563
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0096 0.1262
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Leishmania major metacaspase, putative 0.0024 0.0005 0.0006
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0073 0.0129 0.0219
Echinococcus granulosus neuropeptide receptor 0.0152 0.0328 0.056
Mycobacterium ulcerans hypothetical protein 0.0026 0.001 0.0018
Echinococcus granulosus glutamate receptor 2 0.0088 0.0166 0.0283
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0152 0.0328 0.056
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0044 0.0057 0.0097
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0273 0.063 0.1079
Loa Loa (eye worm) jmjC domain-containing protein 0.0202 0.0452 0.0773
Echinococcus multilocularis isocitrate dehydrogenase 0.0024 0.0006 0.0008
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0026 0.001 0.0017
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0485 0.1162 0.1991
Schistosoma mansoni hypothetical protein 0.0118 0.0242 0.0415
Brugia malayi hypothetical protein 0.0046 0.0062 0.019
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0118 0.0242 0.0821
Schistosoma mansoni glutamate synthase 0.0026 0.001 0.0017
Brugia malayi prolyl oligopeptidase family protein 0.0062 0.0102 0.0311
Loa Loa (eye worm) hypothetical protein 0.0706 0.1715 0.2939
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.0151
Echinococcus multilocularis NMDA receptor 0.0092 0.0175 0.0299
Echinococcus multilocularis sodium channel protein 0.0043 0.0054 0.009
Schistosoma mansoni lamin 0.0071 0.0123 0.0211
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1127
Schistosoma mansoni microtubule-associated protein tau 0.1446 0.3571 0.6121
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0026 0.001 0.0073
Brugia malayi Melatonin receptor type 1A 0.0152 0.0328 0.1002
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0106 0.021 0.036
Schistosoma mansoni glutamate synthase 0.0026 0.001 0.0017
Brugia malayi hypothetical protein 0.0154 0.0331 0.1012
Entamoeba histolytica hypothetical protein 0.0061 0.0099 0.1297
Onchocerca volvulus 0.0071 0.0123 0.0554
Echinococcus granulosus apoptotic protease activating factor 1 0.0055 0.0084 0.0142
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.008 0.1083
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.0063
Brugia malayi glutamate synthase 0.0026 0.001 0.003
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0051 0.0087
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.2334
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0025 0.0008 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0096 0.0165
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0051 0.0229
Echinococcus multilocularis lamin dm0 0.0071 0.0123 0.0209
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0096 0.131
Schistosoma mansoni biogenic amine receptor 0.0152 0.0328 0.0562
Schistosoma mansoni neuropeptide receptor 0.0152 0.0328 0.0562
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0018 0.0178
Echinococcus multilocularis gamma secretase subunit aph 1 0.0096 0.0187 0.0319
Echinococcus multilocularis RUN 0.0153 0.0329 0.0563
Onchocerca volvulus 0.0152 0.0328 0.1479
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0121 0.025 0.1505
Loa Loa (eye worm) hypothetical protein 0.0061 0.0099 0.0167
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0097 0.0187 0.0632
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0162 0.035 0.0599
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Brugia malayi hypothetical protein 0.0054 0.008 0.0244
Loa Loa (eye worm) glutamate receptor 2 0.0071 0.0123 0.0209
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1127
Echinococcus granulosus tm gpcr rhodopsin 0.0152 0.0328 0.056
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0052 0.0076 0.0129
Treponema pallidum NADH oxidase 0.0097 0.0187 0.0616
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Echinococcus granulosus sex peptide receptor 0.0152 0.0328 0.056
Onchocerca volvulus 0.0152 0.0328 0.1479
Onchocerca volvulus 0.0057 0.0089 0.0402
Schistosoma mansoni glutamate receptor AMPA 0.0071 0.0123 0.0211
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0073 0.0129 0.0219
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.001 0.0066
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0313 0.073 0.0725
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0078 0.0142 0.0241
Trypanosoma brucei trypanothione reductase 0.0279 0.0644 0.8813
Schistosoma mansoni coup transcription factor 0.0042 0.0051 0.0087
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0152 0.0328 0.056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1012
Echinococcus multilocularis G-protein coupled receptor, putative 0.0152 0.0328 0.056
Schistosoma mansoni neuropeptide receptor 0.0152 0.0328 0.0562
Schistosoma mansoni hypothetical protein 0.0733 0.1782 0.3054
Loa Loa (eye worm) hypothetical protein 0.0905 0.2215 0.3795
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0071 0.0123 0.0209
Giardia lamblia Heat shock protein HSP 90-alpha 0.01 0.0197 0.2225
Onchocerca volvulus Matrilysin homolog 0.0099 0.0192 0.0869
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.0008
Brugia malayi RE15519p 0.0152 0.0328 0.1002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2523
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0152 0.0328 0.056
Trypanosoma cruzi metacaspase, putative 0.0024 0.0005 0.0054
Toxoplasma gondii hypothetical protein 0.0154 0.0331 0.1127
Echinococcus granulosus JmjC domain containing protein 4 0.0202 0.0452 0.0773
Schistosoma mansoni hypothetical protein 0.0152 0.0328 0.0562
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0026 0.001 0.0032
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0153 0.0329 0.0563
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0025 0.0009 0.0013
Schistosoma mansoni lipoxygenase 0.0493 0.1181 0.2025
Schistosoma mansoni hypothetical protein 0.0152 0.0328 0.0562
Echinococcus granulosus lysine specific demethylase 5A 0.069 0.1675 0.2869
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.001 0.0005
Echinococcus multilocularis phd:f box containing protein 0.0356 0.0837 0.1433
Leishmania major DNA polymerase eta, putative 0.0034 0.003 0.0349
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0118 0.0241 0.0739
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0039 0.0065
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0152 0.0328 0.1002
Schistosoma mansoni histamine h1 receptor 0.0152 0.0328 0.0562
Schistosoma mansoni hypothetical protein 0.0152 0.0328 0.0562
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0313 0.073 0.2508
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1177 0.2895 1
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0033
Brugia malayi hypothetical protein 0.0153 0.0329 0.1007
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0092 0.0175 0.0299
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1177 0.2895 1
Echinococcus multilocularis geminin 0.0733 0.1782 0.3053
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0026 0.001 0.0123
Onchocerca volvulus 0.0153 0.0329 0.1487
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.0226 0.1359
Brugia malayi G-protein coupled receptor 0.0152 0.0328 0.1002
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.0151
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Loa Loa (eye worm) heat shock protein 90 0.0117 0.024 0.0409
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.011 0.0222 0.0752
Loa Loa (eye worm) hypothetical protein 0.027 0.0621 0.1063
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0321 0.0548
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0024 0.0005 0.0006
Leishmania major nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.2297
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0073 0.0129 0.0764
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0029 0.0018 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0097 0.0187 0.0632
Loa Loa (eye worm) hypothetical protein 0.0146 0.0311 0.0532
Echinococcus multilocularis sex peptide receptor 0.0152 0.0328 0.056
Onchocerca volvulus 0.0152 0.0328 0.1479
Schistosoma mansoni glutamate receptor NMDA 0.0071 0.0123 0.0211
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.001 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0016 0.0207
Plasmodium vivax amine transporter, putative 0.0154 0.0331 0.1127
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Echinococcus multilocularis thymidylate synthase 0.0068 0.0116 0.0197
Echinococcus multilocularis neuropeptide s receptor 0.0152 0.0328 0.056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0029 0.005
Schistosoma mansoni amine GPCR 0.0152 0.0328 0.0562
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.001 0.012
Echinococcus multilocularis glutamate synthase 0.0026 0.001 0.0015
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0024 0.0005 0.0015
Mycobacterium ulcerans glutaminase 0.0157 0.034 0.1162
Brugia malayi isocitrate dehydrogenase 0.0024 0.0006 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0234 0.0533 0.0912
Echinococcus granulosus neuropeptide s receptor 0.0152 0.0328 0.056
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0029 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus g-protein coupled receptor 0.0152 0.0328 0.056
Plasmodium falciparum endoplasmin, putative 0.0085 0.0159 0.0534
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0001 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0078 0.0142 0.0474
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0006 0.0008
Loa Loa (eye worm) norepinephrine transporter 0.0905 0.2215 0.3795
Onchocerca volvulus 0.0154 0.0331 0.1493
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0051 0.0085
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0038 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Trichomonas vaginalis mercuric reductase, putative 0.0097 0.0187 0.0183
Echinococcus multilocularis caspase 2 0.0079 0.0143 0.0244
Toxoplasma gondii selenide, water dikinase 0.0026 0.001 0.0017
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0096 0.131
Trichomonas vaginalis heat shock protein, putative 0.01 0.0197 0.0193
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Onchocerca volvulus Cell death protein 3 homolog 0.0079 0.0143 0.0647
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0152 0.0328 0.0562
Trichomonas vaginalis DNA polymerase eta, putative 0.0029 0.0018 0.0013
Brugia malayi glutathione reductase 0.0279 0.0644 0.1969
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0116
Mycobacterium tuberculosis Conserved hypothetical protein 0.0029 0.0018 0.0082
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0051 0.0073 0.0236
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0062 0.0102 0.0172
Brugia malayi RNA binding protein 0.0033 0.0029 0.0089
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1127
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0051 0.0155
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0011 0.0017
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0051 0.0085
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0056 0.0085 0.0496
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0016 0.0207
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0078 0.0141 0.1884
Echinococcus multilocularis dna polymerase kappa 0.0029 0.0018 0.0029
Trypanosoma cruzi oligopeptidase b 0.0025 0.0008 0.0091
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0061 0.0099 0.0167
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0014
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Brugia malayi Dopamine receptor 0.0152 0.0328 0.1002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0051 0.0085
Brugia malayi putative neuropeptide receptor 0.0152 0.0328 0.1002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0152 0.0328 0.0562
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Brugia malayi jmjC domain containing protein 0.0202 0.0452 0.1383
Schistosoma mansoni sodium/chloride dependent transporter 0.0905 0.2215 0.3797
Schistosoma mansoni hypothetical protein 0.0024 0.0006 0.001
Trypanosoma cruzi metacaspase 5, putative 0.0024 0.0005 0.0054
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0313 0.073 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0061 0.0099 0.1291
Schistosoma mansoni cathepsin D (A01 family) 0.0071 0.0124 0.0213
Onchocerca volvulus 0.0152 0.0328 0.1479
Loa Loa (eye worm) hypothetical protein 0.0081 0.0148 0.0251
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0097 0.0187 0.0616
Echinococcus multilocularis tar DNA binding protein 0.0033 0.0029 0.0048
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0096 0.0163
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.009 0.0171 0.0293
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.001 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0152 0.0328 0.056
Schistosoma mansoni aldehyde dehydrogenase 0.0273 0.063 0.1081
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0024 0.0006 0.0009
Trypanosoma cruzi metacaspase 5, putative 0.0024 0.0005 0.0054
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus 7tm_1 domain containing protein 0.0152 0.0328 0.056
Onchocerca volvulus 0.0154 0.0331 0.1493
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0061 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0033
Echinococcus multilocularis serotonin receptor 0.2349 0.5834 1
Echinococcus granulosus expressed protein 0.0025 0.0009 0.0013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0152 0.0328 0.056
Onchocerca volvulus 0.0152 0.0328 0.1479
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0051 0.0073 0.0219
Plasmodium vivax JmjC domain containing protein 0.0242 0.0552 0.1892
Onchocerca volvulus 0.0152 0.0328 0.1479
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0097 0.0187 0.2518
Schistosoma mansoni opsin-like receptor 0.0152 0.0328 0.0562
Onchocerca volvulus 0.0152 0.0328 0.1479
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0202 0.0452 0.6191
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0321 0.0548
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0025 0.0008 0.0011
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0051 0.0087
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0051 0.0087
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0051 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0087 0.0163 0.0277
Schistosoma mansoni terminal deoxycytidyl transferase 0.0029 0.0018 0.0031
Echinococcus granulosus L aminoadipate semialdehyde 0.0181 0.0399 0.0682
Schistosoma mansoni amine GPCR 0.0152 0.0328 0.0562
Leishmania major DNA polymerase kappa, putative 0.0029 0.0018 0.0184
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Brugia malayi jmjC domain containing protein 0.0286 0.0661 0.2024
Brugia malayi hypothetical protein 0.0056 0.0085 0.026
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0154 0.0331 0.0565
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0026 0.001 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0152 0.0328 0.0562
Echinococcus granulosus Polycystic kidney disease protein 0.0153 0.0329 0.0563
Brugia malayi Pre-B cell enhancing factor precursor 0.0485 0.1162 0.3554
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0078 0.0142 0.0243
Schistosoma mansoni amine GPCR 0.0152 0.0328 0.0562
Trypanosoma brucei NADH dehydrogenase 0.0026 0.001 0.0066
Onchocerca volvulus 0.0061 0.0099 0.0445
Loa Loa (eye worm) hypothetical protein 0.0488 0.1168 0.2001
Trichomonas vaginalis conserved hypothetical protein 0.1 0.2452 0.2449
Trichomonas vaginalis heat shock protein, putative 0.0068 0.0117 0.0112
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0146 0.0311 0.0952
Trypanosoma brucei hypothetical protein, conserved 0.0051 0.0073 0.094
Brugia malayi follicle stimulating hormone receptor 0.0279 0.0645 0.1974
Brugia malayi G protein-coupled receptor 0.0152 0.0328 0.1002
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.011 0.0222 0.0735
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0096
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0097 0.0187 0.0319
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.009 0.0171 0.0575
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0051 0.0085
Brugia malayi jmjC domain containing protein 0.0202 0.0452 0.1383
Leishmania major oligopeptidase b 0.0025 0.0008 0.0043
Toxoplasma gondii Hsp90 domain-containing protein 0.0445 0.1061 0.3655
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0051 0.0087
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0313 0.073 1
Brugia malayi hypothetical protein 0.0153 0.0329 0.1007
Echinococcus multilocularis glutamate receptor 2 0.0114 0.0232 0.0395
Brugia malayi Matrixin family protein 0.0044 0.0057 0.0174
Loa Loa (eye worm) jmjC domain-containing protein 0.0202 0.0452 0.0773
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0087 0.0163 0.0497
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.001 0.012
Onchocerca volvulus 0.0044 0.0057 0.0257
Mycobacterium ulcerans ferredoxin reductase 0.0026 0.001 0.0018
Brugia malayi nuclear hormone receptor 0.0042 0.0051 0.0155
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Brugia malayi Isocitrate dehydrogenase 0.0024 0.0006 0.0017
Brugia malayi hypothetical protein 0.0035 0.0032 0.0099
Echinococcus multilocularis lysine specific demethylase 6a 0.0202 0.0452 0.0773
Loa Loa (eye worm) G-protein coupled receptor 0.0152 0.0328 0.056
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1177 0.2895 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0036 0.0037 0.0491
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0097 0.0187 0.2559
Brugia malayi Protein kinase domain containing protein 0.013 0.0272 0.0831
Echinococcus granulosus lamin dm0 0.0071 0.0123 0.0209
Echinococcus multilocularis expressed protein 0.0025 0.0009 0.0013
Echinococcus multilocularis neuropeptides capa receptor 0.0152 0.0328 0.056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0152 0.0328 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0051 0.0085
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0061 0.0099 0.1297
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0057 0.0089 0.0152
Trypanosoma brucei heat shock protein 84, putative 0.0078 0.0141 0.1879
Echinococcus granulosus neuropeptide Y receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0051 0.0085
Treponema pallidum nicotinate phosphoribosyltransferase 0.009 0.0171 0.0559
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.008 0.026
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0061 0.0099 0.1339
Trypanosoma cruzi heat shock protein 85, putative 0.0117 0.024 0.3279
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Echinococcus multilocularis JmjC domain containing protein 4 0.0202 0.0452 0.0773
Plasmodium falciparum plasmepsin IV 0.0024 0.0006 0.0004
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0026 0.001 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0202 0.0452 0.0773
Trichomonas vaginalis CAMK family protein kinase 0.0026 0.0012 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0152 0.0328 0.056
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1177 0.2895 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0051 0.0085
Trypanosoma cruzi heat shock protein 90, putative 0.01 0.0197 0.2695
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0142 0.0243
Echinococcus multilocularis glutamate receptor 2 0.0101 0.0198 0.0337
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0097 0.0187 0.0573
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0152 0.0328 0.056
Onchocerca volvulus 0.0152 0.0328 0.1479
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0313 0.073 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0051 0.0155
Loa Loa (eye worm) transcription factor SMAD2 0.0179 0.0395 0.0676
Schistosoma mansoni endoplasmin 0.0117 0.024 0.0411
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0101 0.0199 0.0339
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0092 0.0175 0.0299
Echinococcus granulosus expressed protein 0.0186 0.0411 0.0702
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Brugia malayi F/Y-rich N-terminus family protein 0.014 0.0297 0.0908
Toxoplasma gondii thioredoxin reductase 0.0279 0.0644 0.221
Brugia malayi hypothetical protein 0.0055 0.0084 0.0256
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.001 0.012
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0029 0.005
Schistosoma mansoni transcription factor LCR-F1 0.0056 0.0085 0.0146
Toxoplasma gondii heat shock protein HSP90 0.0117 0.024 0.0813
Brugia malayi Calcitonin receptor-like protein seb-1 0.0118 0.0241 0.0739
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0154 0.0331 0.1012
Loa Loa (eye worm) hypothetical protein 0.0061 0.0099 0.0167
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0024 0.0005 0.0006
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0114 0.0232 0.0395
Schistosoma mansoni loxhd1 0.0153 0.0329 0.0564
Schistosoma mansoni glutamate receptor kainate 0.0136 0.0287 0.0492
Loa Loa (eye worm) glutamate receptor 1 0.0101 0.0198 0.0337
Echinococcus multilocularis lamin 0.0071 0.0123 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0051 0.0155
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.008 0.026
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0039 0.012
Brugia malayi G protein-coupled receptor F59B2.13 0.0152 0.0328 0.1002
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0051 0.0087
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0152 0.0328 0.0562
Onchocerca volvulus 0.0152 0.0328 0.1479
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Schistosoma mansoni endoplasmin 0.0117 0.024 0.0411
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0099 0.0094
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0061 0.0099 0.0094
Onchocerca volvulus Huntingtin homolog 0.0065 0.0107 0.0485
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0073 0.0129 0.1717
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0051 0.0085
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0181 0.0399 0.0684
Mycobacterium ulcerans heat shock protein 90 0.011 0.0222 0.0752
Loa Loa (eye worm) hypothetical protein 0.0054 0.008 0.0135
Onchocerca volvulus 0.0905 0.2215 1
Schistosoma mansoni hypothetical protein 0.0153 0.0329 0.0564
Onchocerca volvulus 0.0042 0.0051 0.0229
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0026 0.001 0.012
Loa Loa (eye worm) hypothetical protein 0.0153 0.0329 0.0563
Trichomonas vaginalis heat shock protein, putative 0.0085 0.0159 0.0154
Echinococcus multilocularis heat shock protein 90 0.0117 0.024 0.0409
Giardia lamblia PHD finger protein 15 0.0362 0.0853 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0118 0.0242 0.0821
Toxoplasma gondii hypothetical protein 0.0046 0.006 0.019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0249 0.0427
Echinococcus multilocularis neuropeptide Y receptor 0.0152 0.0328 0.056
Echinococcus multilocularis neuropeptide receptor 0.0152 0.0328 0.056
Schistosoma mansoni caspase-3 (C14 family) 0.0024 0.0005 0.0008
Brugia malayi hypothetical protein 0.0022 0.0001 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0362 0.0853 0.2934
Echinococcus granulosus synaptic glycoprotein sc2 0.0061 0.0099 0.0167
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0096 0.1268
Trichomonas vaginalis glutathione reductase, putative 0.0097 0.0187 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0018 0.0178
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0162 0.035 0.0599
Loa Loa (eye worm) PHD-finger family protein 0.0362 0.0853 0.1461
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0026 0.001 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0018 0.0231
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0152 0.0328 0.0562
Schistosoma mansoni kinase 0.0027 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.027 0.0621 0.1063
Echinococcus multilocularis neuropeptides capa receptor 0.0152 0.0328 0.056
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0051 0.0085
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0267
Onchocerca volvulus 0.0152 0.0328 0.1479
Schistosoma mansoni sulfide quinone reductase 0.0026 0.001 0.0017
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0029 0.0018 0.0184
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0152 0.0328 0.0562
Schistosoma mansoni cathepsin D (A01 family) 0.0071 0.0124 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0097 0.0187 0.2523
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0152 0.0328 0.0562
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Schistosoma mansoni hypothetical protein 0.0362 0.0853 0.1462
Leishmania major C-8 sterol isomerase-like protein 0.0146 0.0311 0.4229
Echinococcus granulosus heat shock protein 0.0117 0.024 0.0409
Brugia malayi ORL1-like opioid receptor 0.0152 0.0328 0.1002
Brugia malayi jmjC domain containing protein 0.0202 0.0452 0.1383
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0051 0.0087
Loa Loa (eye worm) hypothetical protein 0.0529 0.1272 0.2179
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0026 0.001 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0179 0.0395 0.0676
Mycobacterium tuberculosis Probable oxidoreductase 0.0192 0.0428 0.2597
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0097 0.0187 0.0616
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0061 0.0099 0.0169
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0051 0.0155
Trichomonas vaginalis heat shock protein, putative 0.0117 0.024 0.0235
Onchocerca volvulus 0.0027 0.0013 0.006
Plasmodium falciparum glutathione reductase 0.0097 0.0187 0.0632
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0051 0.0073 0.0219
Plasmodium vivax thioredoxin reductase, putative 0.0279 0.0644 0.221
Onchocerca volvulus Neuropeptide F receptor homolog 0.0152 0.0328 0.1479
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.001 0.012
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0187 0.2559
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0097 0.0187 0.2559
Mycobacterium ulcerans hypothetical protein 0.0313 0.073 0.2509
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0097 0.0187 0.2559
Onchocerca volvulus 0.0621 0.1503 0.6787
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0051 0.0085
Echinococcus granulosus glutamate receptor 2 0.0114 0.0232 0.0395
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0273 0.063 0.8631
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0061 0.0099 0.0094
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.001 0.0032
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0026 0.001 0.0017
Brugia malayi nuclear receptor NHR-88 0.0042 0.0051 0.0155
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0092 0.0175 0.0299
Echinococcus granulosus glutamate synthase 0.0026 0.001 0.0015
Schistosoma mansoni caspase-7 (C14 family) 0.0079 0.0143 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0076 0.0131
Echinococcus granulosus lipoxygenase domain containing protein 0.0153 0.0329 0.0563
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0024 0.0006 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0051 0.0155
Plasmodium falciparum polyprenol reductase, putative 0.0061 0.0099 0.0324
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0485 0.1162 0.199
Echinococcus granulosus prolyl endopeptidase 0.0062 0.0102 0.0172
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0025 0.0008 0.0011
Loa Loa (eye worm) matrixin family protein 0.0107 0.0215 0.0366
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0051 0.0155
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0096 0.0185 0.2493
Brugia malayi Doublecortin family protein 0.0153 0.0329 0.1007
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.008 0.0244
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.002 0.0266
Schistosoma mansoni rab6-interacting 0.0153 0.0329 0.0564
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.1012
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0101 0.0199 0.0339
Echinococcus granulosus glutamate NMDA receptor subunit 0.0071 0.0123 0.0209
Toxoplasma gondii heat shock protein 90, putative 0.0117 0.024 0.0813
Mycobacterium ulcerans hydrolase 0.0054 0.0081 0.0265
Schistosoma mansoni cpg binding protein 0.0253 0.058 0.0995
Schistosoma mansoni DNA polymerase eta 0.0054 0.008 0.0136
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0026 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus geminin 0.0733 0.1782 0.3053
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0025 0.0008 0.0019
Trypanosoma cruzi oligopeptidase b 0.0025 0.0008 0.0091
Plasmodium vivax polyprenol reductase, putative 0.0061 0.0099 0.0324
Entamoeba histolytica disulphide oxidoreductase, putative 0.0026 0.001 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Schistosoma mansoni dihydrofolate reductase 0.0028 0.0015 0.0026
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.009 0.0171 0.0293
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0073 0.0129 0.0221
Echinococcus multilocularis Polycystic kidney disease protein 0.0153 0.0329 0.0563
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0056 0.0085 0.0144
Brugia malayi Dihydrofolate reductase 0.0028 0.0015 0.0046
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0061 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus gamma secretase subunit aph 1 0.0096 0.0187 0.0319
Brugia malayi steroid hormone receptor 0.0042 0.0051 0.0155
Loa Loa (eye worm) glutathione reductase 0.0279 0.0644 0.1102
Schistosoma mansoni biogenic amine receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus hypothetical protein 0.0152 0.0328 0.056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Onchocerca volvulus 0.0152 0.0328 0.1479
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0152 0.0328 0.1002
Plasmodium falciparum thioredoxin reductase 0.0097 0.0187 0.0632
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0078 0.0141 0.0637
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0006
Brugia malayi Dopamine receptor protein 1 0.0152 0.0328 0.1002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0051 0.0085
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0154 0.0331 0.0565
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0152 0.0328 0.0562
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0097 0.0187 0.0633
Trypanosoma brucei heat shock protein, putative 0.0117 0.024 0.3242
Brugia malayi Tachykinin-like peptides receptor 99D 0.0152 0.0328 0.1002
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.013 0.0272 0.0464
Schistosoma mansoni intermediate filament proteins 0.0071 0.0123 0.0211
Loa Loa (eye worm) matrix metalloproteinase 0.0044 0.0057 0.0096
Schistosoma mansoni ATP-binding cassette transporter 0.0071 0.0123 0.0211
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0768 0.1872 0.3208
Brugia malayi Endoplasmin precursor 0.0117 0.024 0.0734
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0076 0.0071
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1177 0.2895 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0051 0.0155
Loa Loa (eye worm) hypothetical protein 0.0033 0.0028 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0096 0.0092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0154 0.0331 0.0565
Loa Loa (eye worm) hypothetical protein 0.0033 0.0028 0.0046
Echinococcus granulosus dna polymerase kappa 0.0029 0.0018 0.0029
Trypanosoma brucei heat shock protein 90, putative 0.0117 0.024 0.3242
Onchocerca volvulus 0.0063 0.0103 0.0467
Trichomonas vaginalis glutaminase, putative 0.0157 0.034 0.0336
Schistosoma mansoni sulfide quinone reductase 0.0026 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0054 0.0081 0.0137
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0313 0.073 0.2233
Echinococcus granulosus heat shock protein 90 0.0117 0.024 0.0409
Schistosoma mansoni glutaminase 0.0157 0.034 0.0583
Toxoplasma gondii prolyl endopeptidase 0.0062 0.0102 0.0335
Toxoplasma gondii aspartyl protease ASP1 0.0024 0.0006 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0154 0.0331 0.0565
Loa Loa (eye worm) glutaminase 2 0.0157 0.034 0.0581
Leishmania major hypothetical protein, conserved 0.0054 0.008 0.104
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0006 0.0002
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.008 0.1035
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0051 0.0229
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.008 0.1079
Leishmania major mitochondrial DNA polymerase beta 0.0212 0.0478 0.6528
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0092 0.0175 0.0299
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0212 0.0478 0.6526
Trichomonas vaginalis endoplasmin, putative 0.0085 0.0159 0.0154
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0026 0.001 0.0015
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0152 0.0328 0.056
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0096 0.0163
Loa Loa (eye worm) hypothetical protein 0.0905 0.2215 0.3795
Brugia malayi jmjC domain containing protein 0.0286 0.0661 0.2024
Echinococcus granulosus rhodopsin orphan GPCR 0.0152 0.0328 0.056
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0152 0.0328 0.0562
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246
Entamoeba histolytica deoxycytidyl transferase, putative 0.0029 0.0018 0.0184
Echinococcus multilocularis expressed protein 0.0186 0.0411 0.0702
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0051 0.0085
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0087 0.0163 0.0279
Schistosoma mansoni myosin xvIII 0.0152 0.0328 0.0562
Leishmania major trypanothione reductase 0.0279 0.0644 0.8814
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0051 0.0085
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0062 0.0102 0.1341
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0096 0.131
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0097 0.0187 0.0321
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0056 0.0086 0.0146
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0071 0.0123 0.0377
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus multilocularis cpg binding protein 0.0253 0.058 0.0993
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0029 0.0018 0.0029
Giardia lamblia Heat shock protein HSP 90-alpha 0.0117 0.024 0.273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0016 0.0154
Schistosoma mansoni amine GPCR 0.0152 0.0328 0.0562
Echinococcus granulosus peptide allatostatin:somatostatin 0.0152 0.0328 0.056
Echinococcus granulosus orexin receptor type 2 0.0152 0.0328 0.056
Treponema pallidum heat shock protein 90 0.011 0.0222 0.0735
Echinococcus granulosus biogenic amine 5HT receptor 0.0152 0.0328 0.056
Echinococcus multilocularis PHD finger protein rhinoceros 0.0362 0.0853 0.1461
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0067
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0096 0.0092
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0096 0.0185 0.0624
Echinococcus granulosus thymidylate synthase 0.0068 0.0116 0.0197
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0154 0.0331 0.0567
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Echinococcus multilocularis g protein coupled receptor 0.0152 0.0328 0.056
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0026 0.001 0.0073
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0051 0.0085
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0152 0.0328 0.056
Brugia malayi gamma-secretase subunit aph-1 0.0096 0.0187 0.0572
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0026 0.001 0.0015
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0029 0.0018 0.0029
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0674 0.1634 0.5638
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0051 0.0085
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0051 0.0085
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0118 0.0242 0.3272
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.001 0.012
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0061 0.0099 0.1297
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0674 0.1634 1
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0024 0.0006 0.0009
Echinococcus granulosus somatostatin receptor 0.0152 0.0328 0.056
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0101 0.0197 0.2661
Echinococcus granulosus RUN 0.0153 0.0329 0.0563
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0026 0.001 0.0015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0097 0.0187 0.0632
Loa Loa (eye worm) isocitrate dehydrogenase 0.0024 0.0006 0.0008
Trypanosoma brucei DNA polymerase beta thumb, putative 0.003 0.002 0.0213
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0097 0.0187 0.2518
Brugia malayi jmjC domain containing protein 0.0768 0.1871 0.5723
Trypanosoma cruzi trypanothione reductase, putative 0.0279 0.0644 0.882
Loa Loa (eye worm) hypothetical protein 0.0054 0.008 0.0135
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Echinococcus granulosus neuropeptides capa receptor 0.0152 0.0328 0.056
Schistosoma mansoni neuropeptide receptor 0.0152 0.0328 0.0562
Loa Loa (eye worm) neuropeptide F receptor 0.0152 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0154 0.0331 0.0565
Entamoeba histolytica hypothetical protein 0.0056 0.0085 0.1109
Echinococcus multilocularis jumonji domain containing 1A 0.0202 0.0452 0.0773
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0152 0.0328 0.056
Onchocerca volvulus 0.0234 0.0533 0.2406
Echinococcus multilocularis neuropeptide receptor A26 0.0152 0.0328 0.056
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0025 0.0008 0.0037
Schistosoma mansoni hypothetical protein 0.0081 0.0148 0.0253
Loa Loa (eye worm) hypothetical protein 0.0042 0.0051 0.0085
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0025 0.0009 0.0013
Brugia malayi hypothetical protein 0.0152 0.0328 0.1002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0065
Leishmania major heat shock protein 83-1 0.0117 0.024 0.3246

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay ChEMBL. 18553954
EC50 (functional) = 2.6 nM Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay ChEMBL. 18553954
EC50 (functional) > 1000 nM Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay ChEMBL. 18553954
Intrinsic activity (functional) = 0.98 Intrinsic activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay relative to isoproterenol ChEMBL. 18553954

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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