Detailed information for compound 1024498

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 304.467 | Formula: C20H32O2
  • H donors: 1 H acceptors: 2 LogP: 4.77 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1C[C@@]23C[C@@H]1CC[C@H]3[C@]1([C@H](CC2)[C@](C)(C=O)CCC1)C
  • InChi: 1S/C20H32O2/c1-18(13-22)7-3-8-19(2)16(18)6-9-20-10-14(4-5-17(19)20)15(11-20)12-21/h13-17,21H,3-12H2,1-2H3/t14-,15-,16+,17-,18-,19+,20-/m0/s1
  • InChiKey: ACXLVKYMISNUFD-ZPNXQJJCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0061 0.0119
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0084 0.0172 0.0202
Brugia malayi MH1 domain containing protein 0.0019 0.0022 0.0026
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.001 0.001
Loa Loa (eye worm) pyruvate kinase 0.0023 0.003 0.0035
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0029 0.0045 0.0093
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.006 0.0117 0.0317
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0034 0.0056 0.0065
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0042 0.0215
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.003 0.0326
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0034 0.0476
Brugia malayi MAP kinase sur-1 0.0034 0.0056 0.0065
Echinococcus multilocularis GPCR, family 2 0.0084 0.0172 0.0172
Schistosoma mansoni zinc finger protein 0.0014 0.001 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0029 0.0045 0.0045
Giardia lamblia Replication factor C, subunit 1 0.0015 0.0012 0.0121
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0029 0.0029
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0027 0.0056
Mycobacterium leprae conserved hypothetical protein 0.006 0.0117 0.2989
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0169 0.0369 0.0369
Mycobacterium ulcerans hypothetical protein 0.006 0.0117 0.2263
Echinococcus multilocularis mitogen activated protein kinase 0.0034 0.0056 0.0056
Plasmodium falciparum plasmepsin V 0.001 0 0.0008
Schistosoma mansoni cpg binding protein 0.0086 0.0177 0.0478
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0029 0.0045 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0045 0.0093
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.007 0.0139 0.3947
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0221 0.0598
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0265 0.0591 0.0696
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0042 0.0809
Brugia malayi Steroid receptor seven-up type 2 0.0029 0.0045 0.0053
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0034 0.0973
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0042 0.0081
Loa Loa (eye worm) thioredoxin reductase 0.0071 0.0141 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0114 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0042 0.0081
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0029 0.0045 0.0045
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.003 0.0061
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.001 0.002
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.001 0.002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.006 0.0117 0.1351
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Schistosoma mansoni hypothetical protein 0.0084 0.0172 0.0465
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0042 0.1069
Loa Loa (eye worm) choline O-acetyltransferase 0.0454 0.1028 0.121
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0042 0.1184
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0132 0.152
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0042 0.1069
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0014 0.0016
Echinococcus granulosus choline O acetyltransferase 0.0454 0.1028 0.2101
Brugia malayi CHE-14 protein 0.0064 0.0125 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0034
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0454 0.1028 0.6329
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.001 0.0011
Schistosoma mansoni tar DNA-binding protein 0.007 0.0139 0.0376
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0048 0.3407
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.006 0.0117 0.0138
Echinococcus granulosus chromobox protein 1 0.0036 0.0061 0.0125
Echinococcus multilocularis sterol regulatory element binding protein 0.0064 0.0125 0.0125
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0029 0.0045 0.0123
Echinococcus granulosus lamin 0.0022 0.0029 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0029 0.0045 0.0053
Chlamydia trachomatis glycogen phosphorylase 0.006 0.0116 0.809
Brugia malayi regulator of G-protein signaling rgs-7 0.0015 0.0013 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0014 0.0157
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0015 0.0012 0.0133
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0527 0.1196 0.1408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Echinococcus multilocularis p2X purinoceptor 4 0.0043 0.0077 0.0077
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0454 0.1028 0.2097
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0034 0.0056 0.0109
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0161 0.035 0.4039
Schistosoma mansoni ap endonuclease 0.0034 0.0056 0.0151
Brugia malayi nuclear hormone receptor 0.0029 0.0045 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0039 0.0428
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0042 0.0483
Schistosoma mansoni hypothetical protein 0.0084 0.0172 0.0465
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.006 0.0117 0.1351
Plasmodium falciparum plasmepsin I 0.001 0 0.0008
Loa Loa (eye worm) hypothetical protein 0.3685 0.8494 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0029 0.0045 0.0439
Trypanosoma cruzi hypothetical protein, conserved 0.0454 0.1028 0.2097
Schistosoma mansoni cpg binding protein 0.0081 0.0166 0.0449
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0042 0.0483
Brugia malayi MH1 domain containing protein 0.0035 0.0058 0.0068
Schistosoma mansoni chromobox protein 0.0036 0.0061 0.0166
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0034 0.0056 0.088
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0015 0.0012 0.0192
Mycobacterium ulcerans glutaminase 0.0234 0.0518 1
Trypanosoma cruzi histone deacetylase, putative 0.0013 0.0007 0.001
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.003 0.0326
Schistosoma mansoni nuclear receptor 0.0014 0.001 0.0026
Echinococcus granulosus beta LACTamase domain containing family member 0.006 0.0117 0.0239
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.001 0.002
Onchocerca volvulus 0.006 0.0117 0.1138
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0034 0.2437
Echinococcus multilocularis pyruvate kinase 0.0023 0.003 0.003
Plasmodium falciparum plasmepsin VIII, putative 0.001 0 0.0008
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.071 0.162 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0029 0.0079
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0058 0.0068
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0196 0.0395
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0013 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0048 0.0094
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0134 0.0286 0.311
Echinococcus granulosus histone deacetylase 6 0.0013 0.0007 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0012 0.0133
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.003 0.029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0028 0.0306
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Brugia malayi nuclear receptor NHR-88 0.0029 0.0045 0.0053
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.001 0.002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0034 0.2431
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0134 0.0286 0.311
Brugia malayi Choline O-acetyltransferase 0.0454 0.1028 0.121
Loa Loa (eye worm) hypothetical protein 0.0094 0.0196 0.023
Loa Loa (eye worm) histone deacetylase 7A 0.0013 0.0007 0.0008
Plasmodium vivax hypothetical protein, conserved 0.006 0.0117 0.8295
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0029 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0029 0.0045 0.0053
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0013 0.0015
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0073 0.0408
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0631 1
Trypanosoma cruzi trypanothione reductase, putative 0.0071 0.0141 0.0284
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0044 0.0081 0.0874
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0082 0.1296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.0369
Brugia malayi Smad1 0.0035 0.0058 0.0068
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0042 0.0049
Echinococcus granulosus mitogen activated protein kinase 3 0.0034 0.0056 0.0114
Brugia malayi hypothetical protein 0.0015 0.0013 0.0015
Brugia malayi Regulator of G protein signaling domain containing protein 0.0015 0.0013 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0082 0.0082
Echinococcus multilocularis pyruvate kinase 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Leishmania major trypanothione reductase 0.0071 0.0141 0.0284
Trypanosoma brucei protein kinase, putative 0.0034 0.0056 0.03
Trypanosoma cruzi histone deacetylase, putative 0.0013 0.0007 0.001
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0022 0.0029 0.028
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0169 0.0369 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.0659
Schistosoma mansoni inositol transporter 0.0169 0.0369 0.0997
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0105 0.0221 0.0452
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0042 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.037
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.071 0.162 0.3307
Onchocerca volvulus 0.0094 0.0196 0.1904
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0196 0.0395
Echinococcus multilocularis regulator of G protein signaling 3 0.0015 0.0013 0.0013
Giardia lamblia Pyruvate kinase 0.0023 0.003 0.0404
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0042 0.2956
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0042 0.0483
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0013 0.0035
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0016 0.0014 0.0016
Schistosoma mansoni zinc finger protein 0.001 0.0002 0.0006
Leishmania major C-8 sterol isomerase-like protein 0.0527 0.1196 0.244
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0196 0.3783
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Brugia malayi N-terminal motif family protein 0.0127 0.0271 0.032
Trichomonas vaginalis esterase, putative 0.006 0.0117 0.1272
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.001 0.001
Mycobacterium tuberculosis Conserved protein 0.006 0.0117 0.1351
Echinococcus multilocularis Smad4 0.0035 0.0058 0.0058
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0043 0.0078 0.0078
Trypanosoma brucei histone deacetylase 1 0.0044 0.0081 0.0455
Brugia malayi acetyltransferase, GNAT family protein 0.0237 0.0526 0.062
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0042 0.0455
Trichomonas vaginalis penicillin-binding protein, putative 0.006 0.0117 0.1272
Echinococcus granulosus histone deacetylase 1 0.0044 0.0081 0.0165
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0042 0.0081
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0033 0.0381
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0048 0.3412
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0015
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0014 0.0028
Echinococcus granulosus sodium:myo inositol cotransporter 0.0169 0.0369 0.0753
Echinococcus granulosus smad 0.0035 0.0058 0.0118
Trypanosoma brucei carnitine O-palmitoyltransferase, putative 0.0454 0.1028 0.6329
Brugia malayi Pre-SET motif family protein 0.0359 0.0807 0.095
Echinococcus multilocularis p2X purinoceptor 4 0.0043 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0132 0.152
Entamoeba histolytica glycogen phosphorylase, putative 0.006 0.0116 0.1839
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0091
Schistosoma mansoni Smad4 0.0035 0.0058 0.0156
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0029 0.0045 0.0045
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0015 0.0012 0.0031
Mycobacterium ulcerans hypothetical protein 0.0094 0.0196 0.3783
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0161 0.035 0.4039
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0015 0.0012 0.0014
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0016 0.0014 0.0016
Brugia malayi Histone deacetylase 1 0.0044 0.0081 0.0095
Echinococcus granulosus Niemann Pick C1 protein 0.0148 0.0321 0.0656
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.0659
Plasmodium falciparum plasmepsin VII 0.001 0 0.0008
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0044 0.0081 0.0874
Giardia lamblia Glycogen phosphorylase 0.006 0.0116 0.178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0196 0.31
Echinococcus multilocularis histone deacetylase 6 0.0013 0.0007 0.0007
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0454 0.1028 0.2097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0015
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0082 0.0162
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0034 0.0169
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0034 0.0056 0.1076
Echinococcus granulosus lamin dm0 0.0022 0.0029 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0454 0.1028 0.2097
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0064 0.0125 0.0147
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0084 0.0172 0.0352
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0015 0.0013 0.0036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0105 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0025 0.0268
Giardia lamblia GTOR 0.0045 0.0082 0.1233
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0084 0.0172 0.0172
Brugia malayi MH1 domain containing protein 0.0019 0.0022 0.0026
Leishmania major pyruvate kinase 0.0023 0.003 0.0056
Trypanosoma cruzi FHA domain containing protein, putative 0.0015 0.0012 0.002
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0042 0.1069
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.007 0.0139 0.1511
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.001 0.0002 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0029 0.0045 0.0439
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.001 0.002
Schistosoma mansoni RAR-like nuclear receptor 0.0029 0.0045 0.0123
Onchocerca volvulus Huntingtin homolog 0.01 0.021 0.204
Schistosoma mansoni Smad4 0.0015 0.0014 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.0117 0.1272
Trypanosoma brucei C-8 sterol isomerase, putative 0.0527 0.1196 0.7371
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0454 0.1028 0.2097
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0134 0.0286 0.0337
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0014 0.0157
Leishmania major histone deacetylase, putative 0.0013 0.0007 0.001
Schistosoma mansoni hypothetical protein 0.0061 0.012 0.0324
Echinococcus multilocularis protein dispatched 1 0.0073 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0061 0.012 0.0324
Plasmodium falciparum plasmepsin IV 0.001 0 0.0008
Mycobacterium tuberculosis Conserved protein 0.006 0.0117 0.1351
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.0002 0.0005
Onchocerca volvulus Histone deacetylase 10 homolog 0.0013 0.0007 0.0068
Plasmodium falciparum thioredoxin reductase 0.0071 0.0141 1
Echinococcus multilocularis chromobox protein 1 0.0036 0.0061 0.0061
Echinococcus granulosus glycogen phosphorylase 0.006 0.0116 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.003 0.003
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.003 0.029
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.003 0.0056
Brugia malayi Nuclear hormone receptor E75 0.0014 0.001 0.0011
Brugia malayi steroid hormone receptor 0.0029 0.0045 0.0053
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0134 0.0286 0.311
Entamoeba histolytica pyruvate kinase, putative 0.0016 0.0014 0.0223
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0015 0.0013 0.0143
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0043 0.0078 0.0159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Leishmania major histone deacetylase, putative 0.0013 0.0007 0.001
Schistosoma mansoni pyruvate kinase 0.0023 0.003 0.0081
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.071 0.162 0.1907
Echinococcus granulosus histone deacetylase 6 0.0013 0.0007 0.0015
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0011 0.0123
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0127 0.0271 0.0319
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0117 0.0234
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.001 0.0011
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0015 0.0012 0.0236
Schistosoma mansoni smad1 5 8 and 0.0035 0.0058 0.0156
Schistosoma mansoni topbp1 0.0015 0.0012 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0029 0.0045 0.0053
Trichomonas vaginalis CMGC family protein kinase 0.0034 0.0056 0.0603
Brugia malayi Bromodomain containing protein 0.001 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0025 0.0268
Onchocerca volvulus Bile acid receptor homolog 0.0029 0.0045 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0666
Brugia malayi Sodium:solute symporter family protein 0.0043 0.0078 0.0091
Schistosoma mansoni steroid hormone receptor ad4bp 0.0029 0.0045 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0012 0.0133
Echinococcus granulosus beta-adrenergic receptor kinase 0.0016 0.0014 0.0028
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.006 0.0117 0.0138
Mycobacterium tuberculosis Probable esterase LipL 0.006 0.0117 0.1351
Plasmodium vivax histone deacetylase 2, putative 0.0013 0.0007 0.0494
Mycobacterium leprae Probable pyruvate kinase PykA 0.0023 0.003 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0631 1
Plasmodium falciparum plasmepsin III 0.001 0 0.0008
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0013 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0105 0.0221 0.0221
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0297 0.3426
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0034 0.0056 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.3685 0.8494 1
Plasmodium falciparum plasmepsin II 0.001 0 0.0008
Schistosoma mansoni tar DNA-binding protein 0.007 0.0139 0.0376
Schistosoma mansoni high-affinity choline transporter 0.0043 0.0078 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0014 0.0038
Onchocerca volvulus 0.0081 0.0166 0.1615
Onchocerca volvulus 0.0043 0.0078 0.0753
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Trichomonas vaginalis glycogen phosphorylase, putative 0.006 0.0116 0.1262
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Treponema pallidum NADH oxidase 0.0024 0.0034 0.0546
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0015 0.0013 0.0027
Brugia malayi nuclear receptor NHR-88 0.0014 0.001 0.0011
Echinococcus multilocularis cpg binding protein 0.0086 0.0177 0.0177
Schistosoma mansoni tar DNA-binding protein 0.007 0.0139 0.0376
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.01 0.0205
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0165
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0056 0.0605
Brugia malayi Heterochromatin protein 1 0.0036 0.0061 0.0072
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0196 0.3783
Trichomonas vaginalis penicillin-binding protein, putative 0.006 0.0117 0.1272
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.006 0.0117 0.2263
Plasmodium vivax histone acetyltransferase GCN5, putative 0.007 0.0139 0.9858
Loa Loa (eye worm) TAR-binding protein 0.007 0.0139 0.0163
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.001 0.0092
Brugia malayi PXA domain containing protein 0.0015 0.0013 0.0015
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0034 0.0056 1
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.2127 0.4892 1
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0048 0.0255
Leishmania major histone deacetylase, putative 0.0044 0.0081 0.016
Leishmania major histone deacetylase, putative 0.0044 0.0081 0.016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0034 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0165
Schistosoma mansoni P2X receptor subunit 0.0043 0.0077 0.0207
Plasmodium falciparum glutathione reductase 0.0071 0.0141 1
Echinococcus granulosus tumor protein p63 0.0561 0.1275 0.2606
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Echinococcus granulosus Niemann Pick C1 protein 0.0212 0.0468 0.0957
Schistosoma mansoni histone deacetylase hda2 0.0013 0.0007 0.0019
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0042 0.0809
Onchocerca volvulus 0.0028 0.0042 0.0406
Toxoplasma gondii histone deacetylase HDAC4 0.0013 0.0007 0.0198
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Brugia malayi PXA domain containing protein 0.0015 0.0013 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0014 0.001 0.0026
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0042 0.0081
Echinococcus multilocularis FTZ F1 alpha 0.0029 0.0045 0.0045
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0015 0.0013 0.0036
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0034 0.0056 0.0814
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0014 0.0016
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0061 0.0332
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0027 0.0032
Brugia malayi CHD4 protein 0.0011 0.0002 0.0003
Toxoplasma gondii histone deacetylase HDAC2 0.0044 0.0081 0.2281
Trichomonas vaginalis set domain proteins, putative 0.0408 0.0921 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.001 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0012 0.0133
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0015 0.0012 0.0133
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0082 0.0162
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0132 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.0015 0.0013 0.0013
Plasmodium falciparum replication factor C subunit 1, putative 0.0015 0.0012 0.0858
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0034 0.0056 0.0109
Brugia malayi hypothetical protein 0.0015 0.0012 0.0014
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0042 0.0483
Loa Loa (eye worm) latrophilin receptor protein 2 0.0084 0.0172 0.0202
Schistosoma mansoni histone deacetylase 4 5 0.0013 0.0007 0.0019
Loa Loa (eye worm) MH2 domain-containing protein 0.0507 0.1149 0.1353
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0139 0.0164
Plasmodium vivax glutathione reductase, putative 0.0071 0.0141 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.161 0.3699 1
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.003 0.029
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Echinococcus granulosus pyruvate kinase 0.0012 0.0005 0.0009
Schistosoma mansoni histone deacetylase 4 5 0.0013 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Toxoplasma gondii pyruvate kinase PyKII 0.0012 0.0005 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0094 0.0196 0.023
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0631 1
Echinococcus granulosus tar DNA binding protein 0.007 0.0139 0.0284
Loa Loa (eye worm) hypothetical protein 0.0084 0.0172 0.0202
Brugia malayi hypothetical protein 0.003 0.0048 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.01 0.0271
Schistosoma mansoni axis inhibition protein axin 0.0015 0.0013 0.0036
Echinococcus granulosus cpg binding protein 0.0086 0.0177 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0045 0.0053
Echinococcus granulosus chromobox protein 1 0.0036 0.0061 0.0125
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0034 0.0056 0.0642
Plasmodium falciparum plasmepsin IX 0.001 0 0.0008
Onchocerca volvulus 0.0022 0.0029 0.028
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0023 0.003 0.0035
Schistosoma mansoni smad1 5 8 and 0.0035 0.0058 0.0156
Echinococcus multilocularis p2X purinoceptor 4 0.0043 0.0077 0.0077
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0034 0.0973
Brugia malayi tailless protein 0.0014 0.001 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0034 0.0092
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0161 0.035 0.4039
Echinococcus multilocularis histone deacetylase 1 0.0044 0.0081 0.0081
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.006 0.0117 0.1351
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Echinococcus granulosus histone deacetylase 0.0013 0.0007 0.0015
Echinococcus multilocularis pyruvate kinase 0.0012 0.0005 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0082 0.0168
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0042 0.0809
Trichomonas vaginalis bromodomain-containing protein, putative 0.007 0.0139 0.1511
Entamoeba histolytica glycogen phosphorylase, putative 0.0026 0.0038 0.0595
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0141 0.2719
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0179 0.0392 0.4518
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.01 0.01
Schistosoma mansoni sodium/solute symporter 0.0043 0.0078 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0012 0.0133
Loa Loa (eye worm) glutaminase 0.0234 0.0518 0.0609
Plasmodium vivax histone deacetylase 1, putative 0.0044 0.0081 0.5698
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0014 0.0038
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0013 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0014 0.0038
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0094 0.0196 0.3783
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0073 0.0793
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0061 0.0666
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.001 0.0026
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.001 0.0011
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0071
Entamoeba histolytica acyl-coA synthetase, putative 0.0094 0.0196 0.31
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.0659
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0058 0.0156
Echinococcus multilocularis dnaJ subfamily B 0.116 0.2659 0.2659
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0045 0.0053
Plasmodium falciparum histone deacetylase, putative 0.0013 0.0007 0.0501
Schistosoma mansoni glycogen phosphorylase 0.0026 0.0038 0.0102
Loa Loa (eye worm) glutathione reductase 0.0071 0.0141 0.0166
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0034 0.0371
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0527 0.1196 0.1407
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0042 0.0483
Schistosoma mansoni smad 0.0015 0.0014 0.0037
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0009 0.0025
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0026 0.0038 0.0435
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014
Plasmodium falciparum histone deacetylase 2 0.0013 0.0007 0.0501
Brugia malayi hypothetical protein 0.0014 0.001 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0518 0.1176 0.1176
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0034 0.0092
Mycobacterium tuberculosis Probable dehydrogenase 0.0161 0.035 0.4039
Echinococcus granulosus glycogen phosphorylase 0.006 0.0116 0.0238
Onchocerca volvulus 0.0134 0.0286 0.2786
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.001 0.0011
Schistosoma mansoni histone deacetylase 1 2 3 0.0013 0.0007 0.0019
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0058 0.0058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0082 0.0096
Echinococcus granulosus Protein patched homolog 1 0.0064 0.0125 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Schistosoma mansoni glycogen phosphorylase 0.006 0.0116 0.0314
Brugia malayi DKFZp564C0469 protein 0.0015 0.0012 0.0014
Schistosoma mansoni tar DNA-binding protein 0.007 0.0139 0.0376
Echinococcus granulosus histone acetyltransferase KAT2B 0.0231 0.0511 0.1044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0026
Brugia malayi Calcitonin receptor-like protein seb-1 0.0265 0.0591 0.0696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.0659
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0042 0.0809
Echinococcus granulosus p2X purinoceptor 4 0.0043 0.0077 0.0157
Echinococcus multilocularis histone deacetylase 6 0.0013 0.0007 0.0007
Brugia malayi hypothetical protein 0.002 0.0023 0.0027
Schistosoma mansoni histone deacetylase hda2 0.0013 0.0007 0.0019
Loa Loa (eye worm) RNA binding protein 0.007 0.0139 0.0163
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0134 0.0286 0.4496
Echinococcus multilocularis thioredoxin glutathione reductase 0.0071 0.0143 0.0143
Trichomonas vaginalis hypothetical protein 0.001 0.0001 0.0009
Loa Loa (eye worm) heterochromatin protein 1 0.0036 0.0061 0.0072
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.071 0.162 0.3311
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0028 0.0306
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0029 0.0045 0.0093
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Echinococcus multilocularis beta LACTamase domain containing family member 0.006 0.0117 0.0117
Onchocerca volvulus 0.006 0.0117 0.1138
Brugia malayi Histone deacetylase family protein 0.0013 0.0007 0.0008
Schistosoma mansoni hypothetical protein 0.0106 0.0222 0.0601
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.006 0.0117 0.1351
Echinococcus granulosus ecdysone induced protein 78C 0.0029 0.0045 0.0093
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0016 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0011 0.012
Echinococcus granulosus histone deacetylase 3 0.0044 0.0081 0.0165
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0029 0.0045 0.0045
Brugia malayi MH2 domain containing protein 0.0035 0.0058 0.0068
Loa Loa (eye worm) pyruvate kinase 0.0023 0.003 0.0035
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0179 0.0392 0.4518
Loa Loa (eye worm) histone deacetylase 3 0.0044 0.0081 0.0095
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014
Echinococcus granulosus axis inhibition protein axin 0.0015 0.0013 0.0027
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0631 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0034 0.0056 0.0109
Schistosoma mansoni pyruvate kinase 0.0012 0.0005 0.0013
Brugia malayi glutaminase DH11.1 0.0234 0.0518 0.0609
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.001 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.0029 0.0045 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0125 0.1359
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Echinococcus multilocularis glycogen phosphorylase 0.006 0.0116 0.0116
Schistosoma mansoni chromobox protein 0.0036 0.0061 0.0166
Brugia malayi MH2 domain containing protein 0.0035 0.0058 0.0068
Loa Loa (eye worm) hypothetical protein 0.0053 0.01 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0084 0.0172 0.0352
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0082 0.0162
Leishmania major hypothetical protein, conserved 0.0041 0.0073 0.0144
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0071 0.0141 0.1627
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Brugia malayi Thioredoxin reductase 0.0071 0.0141 0.0166
Echinococcus granulosus p2X purinoceptor 4 0.0043 0.0077 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0011 0.012
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0134 0.0286 0.5534
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0034 0.0666
Brugia malayi nuclear receptor NHR-67 0.0014 0.001 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0175 0.0382 0.1032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0132 0.152
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0034 0.0169
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0022 0.0028 0.0272
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0042 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0454 0.1028 0.2097
Echinococcus multilocularis pyruvate kinase 0.0023 0.003 0.003
Echinococcus granulosus thioredoxin glutathione reductase 0.0071 0.0143 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0045 0.0053
Echinococcus granulosus solute carrier family 5 0.0169 0.0369 0.0753
Trypanosoma brucei hypothetical protein, conserved 0.006 0.0117 0.0682
Schistosoma mansoni hypothetical protein 0.0181 0.0397 0.1074
Brugia malayi Pyruvate kinase, M2 isozyme 0.0023 0.003 0.0035
Echinococcus granulosus sodium:glucose cotransporter 0.0169 0.0369 0.0753
Schistosoma mansoni topbp1 0.0015 0.0012 0.0033
Echinococcus granulosus expressed protein 0.0297 0.0664 0.1358
Brugia malayi Latrophilin receptor protein 2 0.0084 0.0172 0.0202
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0014 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0029 0.0045 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0139
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.0117 0.1272
Onchocerca volvulus 0.0454 0.1028 1
Trypanosoma brucei trypanothione reductase 0.0071 0.0141 0.0831
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0139
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0042 0.0809
Echinococcus granulosus sodium:glucose cotransporter 2 0.0169 0.0369 0.0753
Echinococcus granulosus p2X purinoceptor 4 0.0043 0.0077 0.0157
Trypanosoma cruzi histone deacetylase, putative 0.0013 0.0007 0.001
Brugia malayi TAR-binding protein 0.007 0.0139 0.0164
Onchocerca volvulus Huntingtin homolog 0.01 0.021 0.204
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0029 0.0045 0.0053
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0029 0.0045 0.0123
Schistosoma mansoni hypothetical protein 0.0084 0.0172 0.0465
Echinococcus multilocularis lamin 0.0022 0.0029 0.0029
Brugia malayi MH2 domain containing protein 0.0507 0.1149 0.1353
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0014 0.0016
Echinococcus multilocularis regulator of G protein signaling 0.0015 0.0013 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Schistosoma mansoni retinoic acid receptor RXR 0.0029 0.0045 0.0123
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0014 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0045 0.0053
Echinococcus multilocularis axis inhibition protein axin 0.0015 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.004 0.0435
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0016
Loa Loa (eye worm) oxidoreductase 0.0028 0.0042 0.0049
Schistosoma mansoni glycogen phosphorylase 0.006 0.0116 0.0314
Entamoeba histolytica hypothetical protein 0.0015 0.0013 0.0207
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Leishmania major carnitine palmitoyltransferase-like protein 0.071 0.162 0.3307
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0056 0.0605
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.001 0.002
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0134 0.0286 0.311
Giardia lamblia Kinase, CMGC MAPK 0.0034 0.0056 0.0813
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.097
Brugia malayi nuclear receptor RXR 0.0014 0.001 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Plasmodium vivax acyl-CoA synthetase, putative 0.007 0.0141 0.997
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Plasmodium falciparum thioredoxin reductase 0.0024 0.0034 0.2437
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0056 0.3935
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0013 0.0035
Entamoeba histolytica glycogen phosphorylase, putative 0.0026 0.0038 0.0595
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0027 0.0074
Plasmodium vivax pyruvate kinase, putative 0.0023 0.003 0.2111
Schistosoma mansoni P2X receptor subunit 0.0043 0.0077 0.0207
Brugia malayi histone deacetylase 1 (HD1) 0.0044 0.0081 0.0095
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.001 0.001
Brugia malayi hypothetical protein 0.01 0.021 0.0247
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0034 0.0056 0.0109
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0013 0.0021
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0027 0.0032
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0073 0.0793
Brugia malayi MH2 domain containing protein 0.0015 0.0014 0.0016
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0055 0.1564
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.007 0.0139 0.3947
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0045 0.0123
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0034 0.0065
Echinococcus multilocularis thyroid hormone receptor alpha 0.0029 0.0045 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0045 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0048 0.3412
Leishmania major pyruvate kinase 0.0023 0.003 0.0056
Mycobacterium ulcerans pyruvate kinase 0.0023 0.003 0.0579
Loa Loa (eye worm) hypothetical protein 0.0078 0.0158 0.0186
Toxoplasma gondii histone deacetylase HDAC1 0.0013 0.0007 0.0198
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0042 0.0483
Entamoeba histolytica acetyltransferase, GNAT family 0.0064 0.0126 0.199
Schistosoma mansoni patched 1 0.0064 0.0125 0.0338
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0064 0.0125 0.0147
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0027 0.0124
Toxoplasma gondii histone deacetylase HDAC3 0.0044 0.0081 0.2281
Brugia malayi MH1 domain containing protein 0.0035 0.0058 0.0068
Loa Loa (eye worm) glutaminase 2 0.0234 0.0518 0.0609
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0023 0.003 0.0035
Onchocerca volvulus 0.0059 0.0114 0.1107
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.001 0.0026
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.2127 0.4892 0.4892
Schistosoma mansoni nuclear receptor 0.0014 0.001 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0039 0.0428
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0181 0.0397 0.0467
Trypanosoma cruzi hypothetical protein, conserved 0.0454 0.1028 0.2097
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0058 0.0118
Echinococcus multilocularis protein patched 0.0064 0.0125 0.0125
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0134 0.0286 0.4535
Plasmodium falciparum plasmepsin X 0.001 0 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.037
Onchocerca volvulus 0.0016 0.0015 0.014
Onchocerca volvulus 0.0454 0.1028 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0034 0.0056 0.0109
Brugia malayi conserved hypotetical protein 0.0014 0.001 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0081 0.0166 0.0195
Onchocerca volvulus 0.0014 0.001 0.0092
Schistosoma mansoni hypothetical protein 0.0061 0.012 0.0324
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0029 0.0045 0.0093
Echinococcus multilocularis tumor protein p63 0.0561 0.1275 0.1275
Echinococcus granulosus histone acetyltransferase KAT2B 0.007 0.0139 0.0285
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0018 0.0019 0.0023
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0034
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0042 0.0809
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0048 0.1364
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0165
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0045 0.0493
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0035
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0002 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Loa Loa (eye worm) hypothetical protein 0.0265 0.0591 0.0696
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0043 0.0078 0.2198
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0034 0.0374
Echinococcus multilocularis zinc finger protein 0.001 0.0002 0.0002
Giardia lamblia Histone deacetylase 0.0044 0.0081 0.1211
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0042 0.0809
Echinococcus granulosus zinc finger protein 0.001 0.0002 0.0004
Echinococcus granulosus high affinity choline transporter 1 0.0043 0.0078 0.0159
Echinococcus multilocularis tar DNA binding protein 0.007 0.0139 0.0139
Plasmodium vivax histone deacetylase, putative 0.0013 0.0007 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.0369
Loa Loa (eye worm) histone methyltransferase 0.0027 0.0041 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0029 0.0045 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Echinococcus multilocularis pyruvate kinase 0.0012 0.0005 0.0005
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.071 0.162 0.162
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0034 0.0371
Entamoeba histolytica hypothetical protein 0.0132 0.0283 0.4476
Brugia malayi A-kinase anchor protein 10, precursor 0.0015 0.0013 0.0015
Echinococcus granulosus geminin 0.0165 0.0359 0.0733
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0034 0.0065
Mycobacterium tuberculosis Probable oxidoreductase 0.0179 0.0392 0.4518
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0029 0.0045 0.0053
Onchocerca volvulus Glycogen phosphorylase homolog 0.006 0.0116 0.1129
Echinococcus multilocularis Regulator of G protein signaling 20 0.0015 0.0013 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0014 0.0037
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0042 0.0483
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0094 0.0196 0.3783
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0012 0.0133
Brugia malayi latrophilin 2 splice variant baaae 0.0181 0.0397 0.0468
Onchocerca volvulus 0.0408 0.0921 0.8962
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0134 0.0286 0.311
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0013 0.0021
Mycobacterium ulcerans lipase LipD 0.006 0.0117 0.2263
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.01 0.0271
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0139 0.0163
Brugia malayi nuclear hormone receptor 0.0014 0.001 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0041 0.0041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0013 0.0021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.007 0.0141 0.1623
Entamoeba histolytica hypothetical protein 0.0015 0.0013 0.0207
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0003 0.0003
Trichomonas vaginalis glycogen phosphorylase, putative 0.006 0.0116 0.1262
Mycobacterium tuberculosis Probable hydrolase 0.006 0.0117 0.1351
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0105 0.0221 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.089
Toxoplasma gondii thioredoxin reductase 0.0071 0.0141 0.4003
Brugia malayi histone deacetylase 11 0.0013 0.0007 0.0008
Schistosoma mansoni histone deacetylase 0.0044 0.0081 0.0218
Plasmodium falciparum plasmepsin VI 0.001 0 0.0008
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0134 0.0286 0.311
Brugia malayi beta-lactamase 0.006 0.0117 0.0138
Echinococcus granulosus mitogen activated protein kinase 0.0034 0.0056 0.0114
Brugia malayi beta-lactamase family protein 0.006 0.0117 0.0138
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0061 0.0666
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0045 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.089
Schistosoma mansoni intermediate filament proteins 0.0022 0.0029 0.0078
Echinococcus multilocularis solute carrier family 5 0.0169 0.0369 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0725
Brugia malayi chromobox protein homolog 3 0.002 0.0025 0.0029
Brugia malayi RNA binding protein 0.007 0.0139 0.0164
Toxoplasma gondii exonuclease III APE 0.0034 0.0056 0.1575
Echinococcus multilocularis expressed conserved protein 0.0139 0.03 0.03
Echinococcus granulosus pyruvate kinase 0.0023 0.003 0.0061
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0029 0.0045 0.0123
Entamoeba histolytica hypothetical protein 0.0132 0.0283 0.4476
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0009 0.0019
Giardia lamblia Histone acetyltransferase GCN5 0.0064 0.0126 0.1932
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0082 0.0464
Schistosoma mansoni cellular tumor antigen P53 0.0082 0.0168 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.037
Treponema pallidum exodeoxyribonuclease (exoA) 0.0034 0.0056 0.0882
Schistosoma mansoni chromosome transmission fidelity factor 0.0015 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0094 0.0196 0.023
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0148 0.0321 0.5083
Echinococcus granulosus pyruvate kinase 0.0023 0.003 0.0061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0034 0.0056 0.0301
Entamoeba histolytica hypothetical protein 0.0015 0.0012 0.0192
Echinococcus granulosus nibrin 0.0015 0.0012 0.0025
Brugia malayi nuclear receptor RXR 0.0015 0.0014 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.006 0.0117 0.0317
Echinococcus granulosus pyruvate kinase 0.0012 0.0005 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0027 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0094 0.0196 0.3783
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0042 0.0455
Echinococcus granulosus histone deacetylase 6 0.0013 0.0007 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0029 0.0045 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.0117 0.1272
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0034 0.6194
Onchocerca volvulus 0.0454 0.1028 1
Brugia malayi PHD-finger family protein 0.001 0.0002 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.001 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0212 0.0468 0.0468
Schistosoma mansoni lamin 0.0022 0.0029 0.0078
Brugia malayi beta-lactamase family protein 0.006 0.0117 0.0138
Schistosoma mansoni bromodomain containing protein 0.001 0.0002 0.0006
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0082 0.0162
Echinococcus multilocularis histone deacetylase 7 0.0013 0.0007 0.0007
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.2127 0.4892 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0012 0.002
Trypanosoma cruzi histone deacetylase, putative 0.0013 0.0007 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0027 0.0293
Chlamydia trachomatis pyruvate kinase 0.0023 0.003 0.1382
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0196 0.0231
Echinococcus multilocularis nibrin 0.0015 0.0012 0.0012
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0014 0.0037
Echinococcus granulosus FTZ F1 alpha 0.0029 0.0045 0.0093
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0084 0.0172 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0139
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0034 0.0056 0.03
Brugia malayi histone deacetylase 3 (HD3) 0.0044 0.0081 0.0095
Brugia malayi carbohydrate phosphorylase 0.006 0.0116 0.0137
Entamoeba histolytica glycogen phosphorylase, putative 0.006 0.0116 0.1839
Brugia malayi ecdysone receptor 0.0014 0.001 0.0011
Onchocerca volvulus 0.006 0.0117 0.1138
Plasmodium vivax replication factor C subunit 1, putative 0.0015 0.0012 0.0851
Mycobacterium leprae Probable lipase LipE 0.006 0.0117 0.2989
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0034 0.0398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Schistosoma mansoni hypothetical protein 0.0132 0.0283 0.0764
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0013 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0034 0.6194
Schistosoma mansoni choline o-acyltransferase 0.0454 0.1028 0.2779
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Trichomonas vaginalis helicase, putative 0.0018 0.0021 0.0223
Brugia malayi ecdysteroid receptor 0.0029 0.0045 0.0053
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0161 0.035 0.894
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0132 0.0283 0.0578
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Brugia malayi hypothetical protein 0.0132 0.0283 0.0333
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Echinococcus multilocularis musashi 0.0022 0.0029 0.0029
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0297 0.5741
Schistosoma mansoni P2X receptor subunit 0.0043 0.0077 0.0207
Echinococcus multilocularis replication factor c subunit 1 0.0015 0.0012 0.0012
Echinococcus multilocularis lamin dm0 0.0022 0.0029 0.0029
Echinococcus granulosus regulator of G protein signaling 3 0.0015 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Schistosoma mansoni axis inhibition protein axin 0.0015 0.0013 0.0036
Echinococcus granulosus histone deacetylase 8 0.0013 0.0007 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0006 0.0063
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0049 0.0092 0.0188
Echinococcus granulosus intermediate filament protein 0.0022 0.0029 0.0059
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0034 0.0041
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.0454 0.1028 0.2097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.037
Leishmania major hypothetical protein, conserved 0.006 0.0117 0.0234
Schistosoma mansoni hypothetical protein 0.0084 0.0172 0.0465
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0029 0.0059
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0385 0.0868 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0023 0.003 0.0141
Plasmodium falciparum acyl-CoA synthetase 0.007 0.0141 0.997
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.2127 0.4892 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0029 0.0045 0.0053
Plasmodium falciparum pyruvate kinase 0.0023 0.003 0.2117
Loa Loa (eye worm) pyruvate kinase 0.0023 0.003 0.0035
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0527 0.1196 0.244
Schistosoma mansoni P2X receptor subunit 0.0043 0.0077 0.0207
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0015 0.0013 0.0013
Plasmodium falciparum glutathione reductase 0.0024 0.0034 0.2437
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0034 0.0056 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0015 0.0012 0.2196
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0042 0.2962
Mycobacterium ulcerans beta-lactamase 0.006 0.0117 0.2263
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Plasmodium falciparum histone acetyltransferase GCN5 0.0064 0.0126 0.8906
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0165
Echinococcus multilocularis histone deacetylase 0.0013 0.0007 0.0007
Onchocerca volvulus 0.0082 0.0168 0.1631
Loa Loa (eye worm) hypothetical protein 0.0269 0.06 0.0707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0055 0.06
Schistosoma mansoni histone deacetylase 0.0044 0.0081 0.0218
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0053 0.01 0.2844
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0033
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.004 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.0369
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0018 0.0019 0.0023
Onchocerca volvulus 0.0014 0.001 0.0092
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0034 0.0065
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0045 0.0053
Entamoeba histolytica hypothetical protein 0.0132 0.0283 0.4476
Brugia malayi hypothetical protein 0.0015 0.0012 0.0014
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0082 0.0464
Echinococcus granulosus Regulator of G protein signaling 20 0.0015 0.0013 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0105 0.0221 0.0452
Schistosoma mansoni inositol transporter 0.0169 0.0369 0.0997
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0061 0.012 0.0324
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0029 0.0045 0.0093
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0359 0.0807 0.095
Loa Loa (eye worm) histone deacetylase 11 0.0013 0.0007 0.0008
Trichomonas vaginalis glutaminase, putative 0.0234 0.0518 0.562
Echinococcus multilocularis high affinity choline transporter 1 0.0043 0.0078 0.0078
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0196 0.4997
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0034 0.2431
Echinococcus multilocularis pyruvate kinase 0.0018 0.0019 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Brugia malayi CXXC zinc finger family protein 0.0081 0.0166 0.0196
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0091
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0151 0.0326 0.0882
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0034 0.0056 0.1572
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0027 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.0454 0.1028 0.2097
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0034 0.2437
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0045 0.0093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.007 0.0141 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0196 0.3783
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0034 0.0666
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0034 0.0065
Onchocerca volvulus 0.0015 0.0012 0.0117
Brugia malayi glutathione reductase 0.0071 0.0141 0.0166
Onchocerca volvulus Heterochromatin protein 1 homolog 0.002 0.0025 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0029 0.0045 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Brugia malayi Pre-SET motif family protein 0.0053 0.01 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0029 0.0045 0.0053
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0029 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0196 0.3783
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0094 0.0196 0.2258
Schistosoma mansoni tar DNA-binding protein 0.007 0.0139 0.0376
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0048 0.0094
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0196 0.0231
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0132 0.152
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0042 0.0215
Trichomonas vaginalis CMGC family protein kinase 0.0034 0.0056 0.0603
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Trypanosoma cruzi histone deacetylase 1, putative 0.0044 0.0081 0.016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0049
Mycobacterium tuberculosis Conserved protein 0.006 0.0117 0.1351
Echinococcus multilocularis beta adrenergic receptor kinase 0.0016 0.0014 0.0014
Mycobacterium tuberculosis Probable reductase 0.0161 0.035 0.4039
Echinococcus granulosus GPCR family 2 0.0084 0.0172 0.0352
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0042 0.0662
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0221 0.0598
Schistosoma mansoni Smad4 0.0015 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Loa Loa (eye worm) pyruvate kinase-PB 0.0016 0.0014 0.0016
Schistosoma mansoni cathepsin D (A01 family) 0.001 0 0.0001
Echinococcus granulosus replication factor c subunit 1 0.0015 0.0012 0.0025
Echinococcus granulosus microtubule associated protein 2 0.161 0.3699 0.756
Trypanosoma cruzi histone deacetylase 1, putative 0.0044 0.0081 0.016
Schistosoma mansoni nuclear hormone receptor 0.0014 0.001 0.0026
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0518 0.1176 0.1384
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0034 0.0056 0.0065
Brugia malayi Nuclear hormone receptor E75 0.0014 0.001 0.0011
Loa Loa (eye worm) Smad1 0.0035 0.0058 0.0068
Echinococcus multilocularis axis inhibition protein axin 0.0015 0.0013 0.0013
Mycobacterium ulcerans esterase/lipase LipP 0.006 0.0117 0.2263
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0196 0.31
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0056 0.3939
Schistosoma mansoni hypothetical protein 0.116 0.2659 0.7189
Loa Loa (eye worm) glycogen phosphorylase 0.006 0.0116 0.0137
Brugia malayi hypothetical protein 0.0015 0.0014 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0454 0.1028 0.6329
Loa Loa (eye worm) beta-lactamase 0.006 0.0117 0.0138
Brugia malayi Choline O-acetyltransferase 0.0454 0.1028 0.121
Onchocerca volvulus 0.0028 0.0042 0.0406
Entamoeba histolytica hypothetical protein 0.0132 0.0283 0.4476
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Schistosoma mansoni smad 0.0035 0.0058 0.0156
Plasmodium vivax SET domain protein, putative 0.0053 0.01 0.7105
Schistosoma mansoni pyruvate kinase 0.0023 0.003 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0073 0.0144
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0045 0.0123
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0034 0.1732
Brugia malayi Pax transcription activation domain interacting protein 0.0015 0.0012 0.0014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.001 0.001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0029 0.0059
Echinococcus granulosus dnaJ subfamily B 0.116 0.2659 0.5435
Schistosoma mansoni cpg binding protein 0.0086 0.0177 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0223
Echinococcus granulosus Smad4 0.0035 0.0058 0.0118
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0179 0.0392 1
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0013 0.0036
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0042 0.1184
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0169
Brugia malayi GH02984p 0.0043 0.0078 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0139
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0042 0.0483
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0009 0.0009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0222 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0029 0.0045 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0013 0.0026
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0042 0.0113
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0148 0.0321 0.0378
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0045 0.0123
Loa Loa (eye worm) transcription factor SMAD2 0.0507 0.1149 0.1353
Treponema pallidum DNA ligase (lig) 0.0015 0.0012 0.0194
Loa Loa (eye worm) hypothetical protein 0.0454 0.1028 0.121
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0042 0.0086
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0029 0.0045 0.0053
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0134 0.0286 0.4535
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0041 0.0083
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0034 0.0065
Trichomonas vaginalis histone deacetylase, putative 0.0044 0.0081 0.0874
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0297 0.7583
Loa Loa (eye worm) steroid hormone receptor 0.0029 0.0045 0.0053
Plasmodium vivax histone deacetylase, putative 0.0013 0.0007 0.0494
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0034 0.0056 0.0109
Echinococcus multilocularis geminin 0.0165 0.0359 0.0359
Schistosoma mansoni transcription factor LCR-F1 0.0132 0.0283 0.0764
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0092 0.0191 0.2206
Schistosoma mansoni smad1 5 8 and 0.0035 0.0058 0.0156
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0042 0.0809
Echinococcus multilocularis microtubule associated protein 2 0.161 0.3699 0.3699
Echinococcus multilocularis histone deacetylase 3 0.0044 0.0081 0.0081
Loa Loa (eye worm) nuclear factor I 0.0019 0.0022 0.0026
Brugia malayi hypothetical protein 0.0518 0.1176 0.1384
Schistosoma mansoni choline o-acyltransferase 0.0454 0.1028 0.2779
Brugia malayi Histone deacetylase family protein 0.0013 0.0007 0.0008
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0021 0.0086
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0265 0.0591 0.0696
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0027 0.0293
Echinococcus granulosus histone deacetylase 7 0.0013 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Entamoeba histolytica histone deacetylase, putative 0.0044 0.0081 0.1274
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0029 0.0029
Trypanosoma brucei carnitine O-acetyltransferase, putative 0.0454 0.1028 0.6329
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0015 0.0012 0.0312
Entamoeba histolytica hypothetical protein 0.0015 0.0013 0.0207
Echinococcus multilocularis chromobox protein 1 0.0036 0.0061 0.0061
Loa Loa (eye worm) acetyltransferase 0.0237 0.0526 0.0619
Echinococcus multilocularis mitogen activated protein kinase 3 0.0034 0.0056 0.0056
Schistosoma mansoni lamin 0.0022 0.0029 0.0078
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0042 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0117 0.0234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0029 0.0045 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0034 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Toxoplasma gondii pyruvate kinase PyK1 0.0023 0.003 0.0845
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0015 0.0012 0.0133
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0015 0.0012 0.0341
Loa Loa (eye worm) hypothetical protein 0.01 0.021 0.0247
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0134 0.0286 0.0337
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0032
Toxoplasma gondii histone deacetylase HDAC5 0.0013 0.0007 0.0198
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.01 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0221 0.0598
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.001 0.0092
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0082 0.1296
Trichomonas vaginalis CMGC family protein kinase 0.0034 0.0056 0.0603
Plasmodium falciparum pyruvate kinase 2 0.0012 0.0005 0.032
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0042 0.0483
Echinococcus multilocularis histone deacetylase 6 0.0013 0.0007 0.0007
Brugia malayi hypothetical protein 0.0015 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Schistosoma mansoni memapsin-2 (A01 family) 0.024 0.0534 0.1443
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0058 0.0118
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0011
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0127 0.0271 0.264
Brugia malayi Pyruvate kinase, muscle isozyme 0.0023 0.003 0.0035
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0161 0.035 0.4039
Leishmania major carnitine/choline acetyltransferase, putative 0.0454 0.1028 0.2097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.089
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0169
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0034 0.0371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.004 0.0435
Schistosoma mansoni ap endonuclease 0.0034 0.0056 0.0151
Echinococcus granulosus axis inhibition protein axin 0.0015 0.0013 0.0027
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0014 0.013
Brugia malayi topoisomerase 0.0015 0.0012 0.0014
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0061 0.0119
Trichomonas vaginalis replication factor C large subunit, putative 0.0015 0.0012 0.0133
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0034 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0048 0.0518
Loa Loa (eye worm) RGS-3 protein 0.0015 0.0013 0.0015
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.0454 0.1028 0.2097
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0014 0.0016
Echinococcus granulosus sterol regulatory element binding protein 0.0064 0.0125 0.0256
Echinococcus granulosus regulator of G protein signaling 3 0.0015 0.0013 0.0027
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0082 0.0096
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0029 0.0034
Brugia malayi Regulator of G protein signaling domain containing protein 0.0015 0.0013 0.0015
Loa Loa (eye worm) histone deacetylase 0.0013 0.0007 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0034 0.0056 0.0603
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0165
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0454 0.1028 0.121
Echinococcus granulosus Glycosyl transferase family 35 0.006 0.0116 0.0238
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0029 0.0045 0.0123
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.001 0.001
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0196 0.0395
Echinococcus multilocularis choline O acetyltransferase 0.0454 0.1028 0.1028
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0042 0.1184
Onchocerca volvulus 0.0106 0.0222 0.216
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0454 0.1028 0.121
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0034 0.0056 0.0109
Schistosoma mansoni bromodomain containing protein 0.001 0.0002 0.0006
Echinococcus multilocularis histone deacetylase 8 0.0013 0.0007 0.0007
Echinococcus multilocularis glycogen phosphorylase 0.006 0.0116 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.0659
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0094 0.0196 0.2258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.004 0.0435
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0196 0.4997
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0237 0.0526 0.0526
Echinococcus granulosus expressed conserved protein 0.0139 0.03 0.0614
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.071 0.162 0.1907
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.001 0 0.0001
Brugia malayi hypothetical protein 0.0014 0.001 0.0011
Entamoeba histolytica glycogenphosphorylase, putative 0.0026 0.0038 0.0595
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0013 0.0036
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0042 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0196 0.0231
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.003 0.0056
Loa Loa (eye worm) hypothetical protein 0.01 0.021 0.0247
Loa Loa (eye worm) hypothetical protein 0.0082 0.0168 0.0197
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0042 0.0483
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0023 0.003 0.0346
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0042 0.0809
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0015 0.0012 0.0133
Loa Loa (eye worm) histone deacetylase 1 0.0044 0.0081 0.0095
Plasmodium falciparum histone deacetylase 1 0.0044 0.0081 0.5701
Leishmania major hypothetical protein, conserved 0.003 0.0048 0.0094
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0044 0.0081 0.0874
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0143
Onchocerca volvulus 0.0029 0.0045 0.0439
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0058 0.0068
Plasmodium vivax thioredoxin reductase, putative 0.0071 0.0141 1
Brugia malayi intermediate filament protein 0.0022 0.0029 0.0034
Brugia malayi Niemann-Pick C1 protein precursor 0.0148 0.0321 0.0378
Toxoplasma gondii ATPase, AAA family protein 0.0015 0.0012 0.0341
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0029
Echinococcus granulosus pyruvate kinase 0.0012 0.0005 0.0009
Echinococcus multilocularis Glycosyl transferase, family 35 0.006 0.0116 0.0116
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0012 0.002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0138
Toxoplasma gondii histone lysine methyltransferase SET1 0.0162 0.0352 1
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.2127 0.4892 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0073 0.0144
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.001 0.0002 0.0002
Plasmodium vivax pyruvate kinase 2, putative 0.0012 0.0005 0.0313
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0105 0.0221 0.026
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0042 0.0049
Onchocerca volvulus 0.0454 0.1028 1
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0014 0.0014
Loa Loa (eye worm) DR-78 0.0014 0.001 0.0011
Onchocerca volvulus 0.0028 0.0042 0.0406
Schistosoma mansoni glutaminase 0.0234 0.0518 0.14
Echinococcus granulosus survival motor neuron protein 1 0.0518 0.1176 0.2403
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0082 0.0222
Schistosoma mansoni cathepsin D (A01 family) 0.001 0 0.0001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0034 0.0093
Schistosoma mansoni DNA ligase IV 0.0015 0.0012 0.0033
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.001 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0053
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0042 0.0483
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0631 0.6856
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0029 0.0045 0.0093
Mycobacterium tuberculosis Probable lipase LipD 0.006 0.0117 0.1351
Echinococcus multilocularis smad 0.0035 0.0058 0.0058
Trypanosoma brucei pyruvate kinase 1 0.0023 0.003 0.0141
Loa Loa (eye worm) PXA domain-containing protein 0.0015 0.0013 0.0015
Brugia malayi hypothetical protein 0.0015 0.0014 0.0016
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0015 0.0012 0.002
Schistosoma mansoni survival motor neuron protein 0.0106 0.0222 0.0601
Schistosoma mansoni coup transcription factor 0.0029 0.0045 0.0123
Trypanosoma cruzi histone deacetylase, putative 0.0013 0.0007 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0053 0.01 0.01
Echinococcus multilocularis Niemann Pick C1 protein 0.0148 0.0321 0.0321
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0095
Brugia malayi exodeoxyribonuclease III family protein 0.0034 0.0056 0.0066
Toxoplasma gondii ABC1 family protein 0.006 0.0117 0.3321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0139
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0026 0.0038 0.0728
Echinococcus multilocularis expressed protein 0.0297 0.0664 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0056 0.015
Onchocerca volvulus 0.0034 0.0057 0.0554
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0123
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0015 0.0013 0.0036
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0237 0.0526 0.1423
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0014

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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