Detailed information for compound 112355

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 397.472 | Formula: C24H23N5O
  • H donors: 0 H acceptors: 4 LogP: 4.39 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(n1)COc1nn2c(nnc2c2c1C1CCC2CC1)c1ccccc1
  • InChi: 1S/C24H23N5O/c1-15-6-5-9-19(25-15)14-30-24-21-17-12-10-16(11-13-17)20(21)23-27-26-22(29(23)28-24)18-7-3-2-4-8-18/h2-9,16-17H,10-14H2,1H3
  • InChiKey: OFFQUPKDTOZERU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131775 All targets in OG5_131775
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor Get druggable targets OG5_129441 All targets in OG5_129441
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, gamma 2 467 aa 449 aa 27.6 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, alpha 2 451 aa 393 aa 25.9 %
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, beta 3 473 aa 441 aa 29.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0064 0.0407 0.0874
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0064 0.0407 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0036 0.0056
Entamoeba histolytica cysteine proteinase, putative 0.0064 0.0407 0.5419
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0064 0.0404 0.0625
Loa Loa (eye worm) cysteine protease 0.0108 0.0751 0.0751
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0044 0.0068
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0579 0.4407 0.6817
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0466 0.1274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Brugia malayi sulfakinin receptor protein 0.008 0.0532 0.0532
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.0204 0.0204
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0064 0.0404 0.0625
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0191 0.0296
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.008 0.0532 0.0532
Entamoeba histolytica hypothetical protein 0.0049 0.0294 0.3918
Plasmodium falciparum DNase I-like protein, putative 0.0015 0.0029 0.0383
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0177 0.2344
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0517 0.1174
Echinococcus granulosus neuropeptide receptor 0.008 0.0532 0.0822
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0064 0.0404 0.0404
Echinococcus granulosus 7TM GPCR rhodopsin 0.008 0.0532 0.0822
Schistosoma mansoni ap endonuclease 0.0076 0.0498 0.077
Loa Loa (eye worm) hypothetical protein 0.0078 0.0517 0.0517
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.0204 0.0353
Onchocerca volvulus 0.0064 0.0404 0.2195
Brugia malayi CCR4 0.0015 0.0029 0.0029
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0294 0.0669
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.0517 0.1174
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0206 0.0358
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.008 0.0532 0.0822
Echinococcus multilocularis neuropeptide FF receptor 2 0.008 0.0532 0.0822
Echinococcus granulosus G protein coupled receptor 139 0.008 0.0532 0.0822
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0309 0.4074
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0064 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0123 0.0864 0.0864
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Echinococcus multilocularis thioredoxin glutathione reductase 0.0109 0.0757 0.1171
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.0958 0.0958
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Echinococcus granulosus neuropeptide Y receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Schistosoma mansoni ap endonuclease 0.0076 0.0498 0.077
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.2218 0.5005
Onchocerca volvulus 0.0049 0.0292 0.1541
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0108 0.0751 0.1708
Onchocerca volvulus 0.0078 0.0517 0.285
Toxoplasma gondii hypothetical protein 0.0048 0.0283 0.1907
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0064 0.0404 0.0625
Schistosoma mansoni importin beta-1 0.0061 0.0384 0.0594
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Giardia lamblia Encystation-specific protease 0.0034 0.0172 0.0987
Echinococcus granulosus cathepsin l cysteine peptidase 0.0108 0.0751 0.1162
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0498 0.2243
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0064 0.0404 0.0625
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0498 0.6623
Schistosoma mansoni smad1 5 8 and 0.0016 0.0036 0.0056
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.017 0.0832
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Brugia malayi RE15519p 0.008 0.0532 0.0532
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.017 0.0766
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0231 0.0231
Plasmodium falciparum serine repeat antigen 4 0.0034 0.0172 0.2277
Onchocerca volvulus 0.008 0.0532 0.2937
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0099 0.0154
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0015 0.0029 0.0011
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0089 0.0138
Schistosoma mansoni hypothetical protein 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0025 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0794 0.7634
Echinococcus granulosus bloom syndrome protein 0.0041 0.0231 0.0357
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0206 0.093
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0206 0.0416
Schistosoma mansoni hypothetical protein 0.0844 0.6466 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) RNA binding protein 0.0061 0.0388 0.0388
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0204 0.0411
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0259 0.04
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0294 0.0669
Brugia malayi Bromodomain containing protein 0.0039 0.021 0.021
Leishmania major GTP-binding protein, putative 0.0045 0.0259 0.1167
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.1003 0.2232
Brugia malayi Melatonin receptor type 1A 0.008 0.0532 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Mycobacterium tuberculosis Probable oxidoreductase 0.0298 0.2224 0.6394
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0064 0.0404 0.0404
Trypanosoma cruzi trypanothione reductase, putative 0.0109 0.0757 0.1673
Schistosoma mansoni cathepsin B (C01 family) 0.0034 0.0172 0.0267
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.0018
Echinococcus multilocularis neuropeptide Y receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0068
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0206 0.0319
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0211 0.278
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0061 0.0023
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0098 0.0109
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0498 1
Loa Loa (eye worm) G-protein coupled receptor 0.008 0.0532 0.0532
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Echinococcus multilocularis g protein coupled receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0108 0.0751 0.0751
Schistosoma mansoni hypothetical protein 0.008 0.0532 0.0822
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0044 0.0068
Echinococcus granulosus cathepsin l1 0.0108 0.0751 0.1162
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0206 0.2746
Giardia lamblia Cysteine protease 0.0034 0.0172 0.0987
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0466 0.0466
Schistosoma mansoni cpg binding protein 0.0032 0.0162 0.025
Schistosoma mansoni lamin 0.0054 0.0327 0.0505
Echinococcus granulosus synaptojanin 1 0.0015 0.0029 0.0045
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Onchocerca volvulus 0.008 0.0532 0.2937
Brugia malayi TAR-binding protein 0.0061 0.0388 0.0388
Schistosoma mansoni pyruvate kinase 0.0017 0.0044 0.0068
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Brugia malayi Cathepsin L-like precursor 0.0078 0.0517 0.0517
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.092
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0034 0.0172 0.2277
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0064 0.0404 0.0404
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0036 0.0056
Plasmodium falciparum thioredoxin reductase 0.0038 0.0204 0.2693
Plasmodium falciparum serine repeat antigen 6 0.0034 0.0172 0.2277
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0259 0.1167
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0091 0.1217
Plasmodium vivax importin-beta 2, putative 0.0061 0.0384 0.5069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.008 0.0532 0.2937
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0029 0.0138 0.0138
Giardia lamblia Cathepsin B precursor 0.0034 0.0172 0.0987
Leishmania major pyruvate kinase 0.0033 0.017 0.0766
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0032 0.0216
Schistosoma mansoni neuropeptide receptor 0.008 0.0532 0.0822
Schistosoma mansoni alpha-1 adrenergic receptor 0.008 0.0532 0.0822
Echinococcus granulosus neuropeptide s receptor 0.008 0.0532 0.0822
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0395 0.0611
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0034 0.0172 0.2277
Mycobacterium tuberculosis Conserved protein 0.0072 0.0466 0.1274
Brugia malayi beta-lactamase 0.0072 0.0466 0.0466
Echinococcus multilocularis orexin receptor type 2 0.008 0.0532 0.0822
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0175 0.0849
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0172 0.0339
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.0751 0.0751
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0259 0.1582
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0191 0.0296
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0051
Treponema pallidum hypothetical protein 0.0015 0.0029 0.0105
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0029 0.0066
Echinococcus granulosus glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Schistosoma mansoni hypothetical protein 0.0135 0.0958 0.1481
Schistosoma mansoni cathepsin F (C01 family) 0.0108 0.0751 0.1162
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0024 0.0162
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Schistosoma mansoni amine GPCR 0.008 0.0532 0.0822
Schistosoma mansoni hypothetical protein 0.0062 0.0395 0.0611
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.008 0.0532 0.0532
Echinococcus multilocularis neuropeptides capa receptor 0.008 0.0532 0.0822
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Schistosoma mansoni hypothetical protein 0.0062 0.0395 0.0611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Loa Loa (eye worm) hypothetical protein 0.0078 0.0517 0.0517
Echinococcus granulosus tm gpcr rhodopsin 0.0582 0.4435 0.6859
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0457 0.3461 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0794 0.2228
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.092
Giardia lamblia Cathepsin L-like protease 0.0034 0.0172 0.0987
Brugia malayi cathepsin L precursor 0.0034 0.0172 0.0172
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0259 0.3418
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Onchocerca volvulus 0.0024 0.0098 0.0412
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Leishmania major importin beta-1 subunit, putative 0.0049 0.0294 0.1327
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Mycobacterium tuberculosis Conserved protein 0.0072 0.0466 0.1274
Schistosoma mansoni neuropeptide f receptor 76f 0.008 0.0532 0.0822
Schistosoma mansoni hypothetical protein 0.008 0.0532 0.0822
Giardia lamblia Hypothetical protein 0.0034 0.0172 0.0987
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0032 0.0144
Schistosoma mansoni opsin-like receptor 0.008 0.0532 0.0822
Toxoplasma gondii cathepsin B 0.0202 0.1482 1
Schistosoma mansoni inositol monophosphatase 0.0038 0.0206 0.0319
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.008 0.0532 0.0822
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0395 0.0611
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0061 0.0808
Echinococcus multilocularis nAChR subunit 0.0034 0.0176 0.0273
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1516 0.1516
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.003 0.0145 0.0145
Giardia lamblia Cathepsin B precursor 0.0202 0.1482 1
Echinococcus multilocularis glycine receptor subunit beta 0.0064 0.0404 0.0625
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.2218 1
Onchocerca volvulus Huntingtin homolog 0.0123 0.0864 0.4871
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0036 0.0056
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Plasmodium vivax unspecified product 0.0064 0.0407 0.5375
Onchocerca volvulus 0.0064 0.0404 0.2195
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0466 0.1274
Schistosoma mansoni glutaminase 0.0578 0.4399 0.6803
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Brugia malayi hypothetical protein 0.0029 0.0138 0.0138
Trypanosoma cruzi ISWI complex protein 0.0015 0.003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0257 0.0257
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0172 0.0267
Schistosoma mansoni cathepsin C 0.0034 0.0172 0.0267
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0029 0.0029
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.008 0.0532 0.0532
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0172 0.2277
Schistosoma mansoni synaptojanin 0.0015 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.0172 0.0172
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.1299 1 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.008 0.0532 0.0822
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0064 0.0407 0.063
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0068
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0034 0.0172 0.2277
Onchocerca volvulus 0.0064 0.0404 0.2195
Loa Loa (eye worm) inositol-1 0.0038 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.008 0.0532 0.0532
Brugia malayi AKH receptor 0.008 0.0532 0.0532
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0029 0.0029
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0051 0.0063
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.004
Leishmania major cysteine peptidase A (CPA) 0.0108 0.0751 0.3387
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0384 0.1731
Schistosoma mansoni biogenic amine (dopamine) receptor 0.008 0.0532 0.0822
Onchocerca volvulus 0.0072 0.0466 0.2557
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0061 0.0061
Schistosoma mansoni smad1 5 8 and 0.0016 0.0036 0.0056
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0177 0.1198
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0498 0.2243
Brugia malayi Thioredoxin reductase 0.0109 0.0757 0.0757
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0015 0.0029 0.0011
Schistosoma mansoni neuropeptide receptor 0.008 0.0532 0.0822
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0061 0.0023
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0061 0.0274
Loa Loa (eye worm) hypothetical protein 0.0039 0.021 0.021
Plasmodium falciparum serine repeat antigen 1 0.0034 0.0172 0.2277
Loa Loa (eye worm) hypothetical protein 0.0078 0.0517 0.0517
Echinococcus granulosus dnaJ subfamily B 0.041 0.3094 0.4786
Echinococcus granulosus lamin 0.0054 0.0327 0.0505
Brugia malayi MH2 domain containing protein 0.0016 0.0036 0.0036
Toxoplasma gondii ABC1 family protein 0.0072 0.0466 0.3146
Entamoeba histolytica cysteine protease, putative 0.0108 0.0751 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0034 0.0172 0.2277
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0145 0.0224
Trypanosoma cruzi ISWI complex protein 0.0015 0.003 0.0014
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0466 0.0721
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0034 0.0172 0.2277
Onchocerca volvulus 0.008 0.0532 0.2937
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Plasmodium falciparum serine repeat antigen 9 0.0034 0.0172 0.2277
Brugia malayi hypothetical protein 0.0033 0.0167 0.0167
Echinococcus multilocularis dna polymerase eta 0.0019 0.0061 0.0094
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni biogenic amine (5HT) receptor 0.008 0.0532 0.0822
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0466 0.0466
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.0204 0.1376
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0034 0.0172 0.0392
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0029 0.0133 0.0133
Entamoeba histolytica recQ family DNA helicase 0.0015 0.0024 0.0319
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0015 0.0029 0.0029
Plasmodium vivax SET domain protein, putative 0.003 0.0145 0.1914
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0388 0.0388
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0498 0.1131
Trypanosoma brucei cysteine peptidase C (CPC) 0.0202 0.1482 0.6683
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0134 0.0134
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0064 0.0404 0.0625
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni opsin-like receptor 0.008 0.0532 0.0822
Trypanosoma brucei RNA editing exonuclease 2 0.0015 0.0029 0.0131
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.1442 0.1442
Entamoeba histolytica cysteine proteinase 1, putative 0.0064 0.0407 0.5419
Trichomonas vaginalis glutaminase, putative 0.0578 0.4399 1
Trypanosoma cruzi cysteine proteinase, putative 0.0064 0.0407 0.0874
Echinococcus multilocularis somatostatin receptor 0.008 0.0532 0.0822
Entamoeba histolytica cysteine proteinase, putative 0.0064 0.0407 0.5419
Brugia malayi Cation transporter family protein 0.0064 0.0404 0.0404
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.008 0.0532 0.0822
Plasmodium falciparum serine repeat antigen 5 0.0034 0.0172 0.2277
Echinococcus granulosus neuropeptide FF receptor 2 0.008 0.0532 0.0822
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0061 0.0094
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0231 0.0524
Echinococcus granulosus neuropeptide Y receptor 0.008 0.0532 0.0822
Brugia malayi neuropeptide F receptor 0.008 0.0532 0.0532
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0114 0.0114
Brugia malayi neuropeptide F receptor 0.008 0.0532 0.0532
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0064 0.0404 0.0404
Echinococcus granulosus microtubule associated protein 2 0.0699 0.5342 0.8263
Echinococcus multilocularis serotonin receptor 0.008 0.0532 0.0822
Echinococcus granulosus glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Plasmodium vivax vivapain-2 0.0108 0.0751 0.9919
Giardia lamblia Cysteine protease 0.0034 0.0172 0.0987
Brugia malayi Serotonin receptor 0.008 0.0532 0.0532
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0015 0.0029 0.0383
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Brugia malayi Bromodomain containing protein 0.0077 0.051 0.051
Schistosoma mansoni neurotransmitter gated ion channel 0.0034 0.0176 0.0273
Onchocerca volvulus 0.008 0.0532 0.2937
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.0126 0.0126
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Echinococcus granulosus cathepsin L 0.0064 0.0407 0.063
Schistosoma mansoni intermediate filament proteins 0.0054 0.0327 0.0505
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0015 0.0029 0.0066
Echinococcus granulosus traf and tnf receptor associated protein 0.0015 0.0029 0.0045
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0206 0.093
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.0046
Loa Loa (eye worm) hypothetical protein 0.0241 0.178 0.178
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0131
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0271 0.0418
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Onchocerca volvulus 0.008 0.0532 0.2937
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0204 0.092
Echinococcus multilocularis allatostatin A receptor 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Echinococcus multilocularis pyruvate kinase 0.0033 0.017 0.0263
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0141 0.1009 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0259 0.1747
Loa Loa (eye worm) glutaminase 0.0578 0.4399 0.4399
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0206 0.0469
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0388 0.0388
Giardia lamblia Cathepsin B precursor 0.0202 0.1482 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0034 0.0172 0.0172
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0015 0.0029 0.0386
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0032 0.0018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.008 0.0532 0.0822
Onchocerca volvulus 0.0015 0.0029 0.0011
Brugia malayi Dopamine receptor protein 2 0.008 0.0532 0.0532
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0172 0.0172
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0078 0.0517 0.1124
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0384 0.1731
Brugia malayi glutaminase DH11.1 0.0578 0.4399 0.4399
Schistosoma mansoni carbon catabolite repressor protein 0.0015 0.0029 0.0045
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0029 0.0138 0.0214
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0271 0.0418
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0015 0.0029 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0061 0.0084
Plasmodium vivax vivapain-2 0.0108 0.0751 0.9919
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0172 0.0267
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.0204 0.092
Giardia lamblia Cysteine protease 0.0034 0.0172 0.0987
Entamoeba histolytica recQ family helicase, putative 0.0014 0.002 0.0262
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0015 0.0029 0.0066
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0498 0.3224
Echinococcus multilocularis smad 0.0016 0.0036 0.0056
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0051
Onchocerca volvulus 0.008 0.0532 0.2937
Toxoplasma gondii cathepsin CPL 0.0108 0.0751 0.5068
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0271 0.0418
Loa Loa (eye worm) beta-lactamase 0.0072 0.0466 0.0466
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Echinococcus multilocularis dnaJ subfamily B 0.041 0.3094 0.4786
Brugia malayi Papain family cysteine protease containing protein 0.0064 0.0407 0.0407
Schistosoma mansoni cathepsin F (C01 family) 0.0078 0.0517 0.0799
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0271 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Schistosoma mansoni opsin-like receptor 0.008 0.0532 0.0822
Entamoeba histolytica hypothetical protein 0.0034 0.0176 0.2349
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0579 0.4407 0.4407
Echinococcus multilocularis neuropeptide receptor A26 0.008 0.0532 0.0822
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0278 0.043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0582 0.4435 0.6859
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0108 0.0751 0.9919
Onchocerca volvulus 0.0108 0.0751 0.4215
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0133 0.0206
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Schistosoma mansoni nAChR subunit 0.0029 0.0138 0.0214
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.008 0.0532 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0172 0.0392
Echinococcus granulosus dna polymerase kappa 0.0019 0.0061 0.0094
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Schistosoma mansoni neuropeptide F-like receptor 0.008 0.0532 0.0822
Echinococcus granulosus fmrfamide receptor 0.008 0.0532 0.0822
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Loa Loa (eye worm) neuropeptide F receptor 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni histamine h1 receptor 0.008 0.0532 0.0822
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0064 0.0404 0.0625
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0029 0.0045
Brugia malayi Pre-SET motif family protein 0.003 0.0145 0.0145
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0206 0.1391
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi RNA binding protein 0.0061 0.0388 0.0388
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.0204 0.2693
Mycobacterium tuberculosis Probable oxidoreductase 0.0141 0.1009 0.2856
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.005
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0384 0.0594
Onchocerca volvulus 0.0072 0.0466 0.2557
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.008 0.0532 0.0822
Toxoplasma gondii cathepsin CPC2 0.0034 0.0172 0.1163
Onchocerca volvulus 0.0108 0.0751 0.4215
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0172 0.2277
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0259 0.0536
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0011
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0064 0.0404 0.0404
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0388 0.06
Brugia malayi PHD-finger family protein 0.0027 0.0118 0.0118
Onchocerca volvulus 0.003 0.0145 0.0686
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0061 0.0094
Leishmania major RNA-editing complex protein MP100, putative 0.0015 0.0029 0.0131
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0133 0.1759
Giardia lamblia Cathepsin B precursor 0.0034 0.0172 0.0987
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0089 0.0138
Onchocerca volvulus 0.0054 0.0327 0.1745
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0259 0.3418
Echinococcus granulosus thioredoxin glutathione reductase 0.0109 0.0757 0.1171
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0051 0.0667
Brugia malayi hypothetical protein 0.0029 0.0138 0.0138
Echinococcus multilocularis snurportin 1 0.0651 0.4965 0.7678
Leishmania major hypothetical protein, conserved 0.0051 0.0309 0.1391
Brugia malayi N-terminal motif family protein 0.0181 0.1316 0.1316
Giardia lamblia Cathepsin B precursor 0.0034 0.0172 0.0987
Onchocerca volvulus 0.0015 0.0029 0.0011
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.017 0.0791
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.017 0.1147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0036 0.0036
Schistosoma mansoni synaptojanin 0.0015 0.0029 0.0045
Loa Loa (eye worm) fibroinase 0.0108 0.0751 0.0751
Giardia lamblia Cathepsin B precursor 0.0202 0.1482 1
Echinococcus multilocularis dro:myosuppressin receptor 0.008 0.0532 0.0822
Echinococcus multilocularis biogenic amine (5HT) receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) ctsf protein 0.0108 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Plasmodium falciparum glutathione reductase 0.0109 0.0757 1
Echinococcus granulosus orexin receptor type 2 0.008 0.0532 0.0822
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Mycobacterium ulcerans short chain dehydrogenase 0.0298 0.2224 0.4998
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0498 0.0498
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.0204 0.092
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0029 0.0386
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0029 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0466 0.106
Plasmodium falciparum pyruvate kinase 0.0033 0.017 0.2244
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0108 0.0751 0.0751
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0061 0.0094
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0172 0.0267
Giardia lamblia Hypothetical protein 0.0034 0.0172 0.0987
Schistosoma mansoni amine GPCR 0.008 0.0532 0.0822
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0466 0.0721
Echinococcus multilocularis fmrfamide receptor 0.008 0.0532 0.0822
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0794 0.2228
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0466 0.6156
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0172 0.2295
Echinococcus granulosus neuropeptides capa receptor 0.008 0.0532 0.0822
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Echinococcus granulosus g protein coupled receptor 0.008 0.0532 0.0822
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0498 0.0498
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0172 0.2295
Schistosoma mansoni acetylcholine receptor-related 0.0029 0.0138 0.0214
Schistosoma mansoni hypothetical protein 0.0015 0.0029 0.0045
Onchocerca volvulus 0.0029 0.0138 0.0647
Echinococcus multilocularis cathepsin L cysteine protease 0.0108 0.0751 0.1162
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0026 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0388 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0177 0.0177
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Onchocerca volvulus 0.0034 0.0172 0.0846
Brugia malayi cathepsin L-like cysteine proteinase 0.0034 0.0172 0.0172
Brugia malayi Cytochrome P450 family protein 0.0026 0.0114 0.0114
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0794 0.2228
Brugia malayi gonadotropin-releasing hormone receptor 2 0.008 0.0532 0.0532
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0037 0.0165
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.0204 0.092
Giardia lamblia Cathepsin B precursor 0.0034 0.0172 0.0987
Brugia malayi ORL1-like opioid receptor 0.008 0.0532 0.0532
Schistosoma mansoni acetylcholine receptor subunit beta 0.0029 0.0138 0.0214
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0294 0.0617
Onchocerca volvulus 0.008 0.0532 0.2937
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0034 0.0172 0.0392
Loa Loa (eye worm) pyruvate kinase 0.0033 0.017 0.017
Plasmodium falciparum glutathione reductase 0.0038 0.0204 0.2693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Loa Loa (eye worm) glutaminase 2 0.0578 0.4399 0.4399
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0172 0.0987
Echinococcus granulosus sex peptide receptor 0.008 0.0532 0.0822
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0466 0.106
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.017 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0172 0.0267
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0064 0.0404 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Brugia malayi putative neuropeptide receptor NPR1 0.008 0.0532 0.0532
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0029 0.0383
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0064 0.0404 0.0625
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.178 0.2753
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0108 0.0751 0.1162
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Loa Loa (eye worm) hypothetical protein 0.0033 0.017 0.017
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0141 0.1009 0.2856
Onchocerca volvulus Cathepsin L homolog 0.0108 0.0751 0.4215
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.008 0.0532 0.0822
Echinococcus granulosus pyruvate kinase 0.0033 0.017 0.0263
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0029 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0172 0.0392
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0175 0.0426
Echinococcus granulosus importin subunit beta 1 0.0061 0.0384 0.0594
Entamoeba histolytica hypothetical protein 0.0034 0.0172 0.2295
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Echinococcus granulosus dna polymerase eta 0.0019 0.0061 0.0094
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0034 0.0172 0.2277
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0064 0.0404 0.0625
Echinococcus multilocularis g protein coupled receptor 0.008 0.0532 0.0822
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0177 0.035
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Brugia malayi Smad1 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0029
Echinococcus multilocularis cathepsin L cysteine protease 0.0108 0.0751 0.1162
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0029 0.0138 0.0214
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.1316 0.7502
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.1751 0.1751
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0032 0.0032
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0206 0.0319
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0235 0.1059
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0138 0.0214
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0024
Brugia malayi isocitrate dehydrogenase 0.0016 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0156 0.1126 0.2473
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.1442 0.1442
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.0204 0.0315
Leishmania major endonuclease/exonuclease protein-like protein 0.0015 0.0029 0.0131
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.0204 0.1376
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0235 0.0481
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.0204 0.092
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.0204 0.0315
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0015 0.0029 0.0045
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0011
Plasmodium vivax pyruvate kinase, putative 0.0033 0.017 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0108 0.0751 0.1708
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0751 0.1659
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0029 0.0383
Echinococcus multilocularis neuropeptide receptor 0.008 0.0532 0.0822
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0032 0.0423
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0153 0.0349
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0498 0.1365
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0131
Giardia lamblia Pyruvate kinase 0.0033 0.017 0.097
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0063
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0498 0.077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0466 0.1009
Loa Loa (eye worm) hypothetical protein 0.023 0.17 0.17
Leishmania major hypothetical protein, conserved 0.0034 0.0177 0.08
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0036 0.0036
Echinococcus multilocularis Smad4 0.0016 0.0036 0.0056
Echinococcus granulosus Smad4 0.0016 0.0036 0.0056
Onchocerca volvulus 0.0108 0.0751 0.4215
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0068
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0034 0.0172 0.2277
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.0204 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0061 0.0084
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.017 0.0832
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.1126 0.3196
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0037 0.0029
Loa Loa (eye worm) hypothetical protein 0.0135 0.0958 0.0958
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1737 0.395
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.1303
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.026 0.1927 0.1927
Onchocerca volvulus 0.0108 0.0751 0.4215
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.005
Schistosoma mansoni hypothetical protein 0.041 0.3094 0.4786
Schistosoma mansoni hypothetical protein 0.008 0.0532 0.0822
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0172 0.0987
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.008 0.0532 0.0822
Schistosoma mansoni zinc finger protein 0.0021 0.0076 0.0118
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.5342 0.8263
Brugia malayi beta-lactamase family protein 0.0072 0.0466 0.0466
Echinococcus multilocularis fmrfamide receptor 0.008 0.0532 0.0822
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Loa Loa (eye worm) pyruvate kinase 0.0033 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Brugia malayi RNA, U transporter 1 0.0173 0.1257 0.1257
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0466 0.0721
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0138 0.0138
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0309 0.1391
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0061 0.0138
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0064 0.0404 0.0625
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0015 0.0029 0.0131
Mycobacterium tuberculosis Conserved protein 0.0072 0.0466 0.1274
Echinococcus granulosus glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0099 0.0154
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0306 0.0643
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0029 0.0011
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0111 0.0172
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0202 0.1482 0.2292
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0138 0.0214
Echinococcus granulosus tm gpcr rhodopsin 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Schistosoma mansoni DNA polymerase eta 0.0019 0.0061 0.0094
Schistosoma mansoni amine GPCR 0.008 0.0532 0.0822
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0181 0.1316 0.1316
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0061 0.0092
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0271 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0172 0.0392
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.0751 1
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0015 0.0029 0.0131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0407 0.1835
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0407 0.0874
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0064 0.0404 0.0404
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0109
Echinococcus granulosus g-protein coupled receptor 0.008 0.0532 0.0822
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0131
Schistosoma mansoni cathepsin S (C01 family) 0.0034 0.0172 0.0267
Onchocerca volvulus 0.0108 0.0751 0.4215
Echinococcus multilocularis G protein coupled receptor 139 0.008 0.0532 0.0822
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0172 0.0392
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0172 0.2277
Mycobacterium tuberculosis Probable reductase 0.0114 0.0794 0.2228
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0034 0.0172 0.0392
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Echinococcus multilocularis neuropeptide receptor 0.008 0.0532 0.0822
Onchocerca volvulus 0.008 0.0532 0.2937
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0177 0.0275
Schistosoma mansoni survival motor neuron protein 0.0049 0.0292 0.0451
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Echinococcus granulosus cysteine protease 0.0064 0.0407 0.063
Giardia lamblia Cysteine protease 0.0034 0.0172 0.0987
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0145 0.0224
Brugia malayi Serotonin/octopamine receptor family protein 7 0.008 0.0532 0.0532
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni smad1 5 8 and 0.0016 0.0036 0.0056
Echinococcus multilocularis deoxyribonuclease 1 2 0.0015 0.0029 0.0045
Echinococcus granulosus cathepsin b 0.0579 0.4407 0.6817
Mycobacterium leprae Probable lipase LipE 0.0072 0.0466 0.4042
Leishmania major hypothetical protein, conserved 0.0015 0.0029 0.0131
Trypanosoma cruzi cysteine protease, putative 0.0064 0.0407 0.0874
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0044 0.0068
Loa Loa (eye worm) pax transcription factor protein 2 0.0236 0.1745 0.1745
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0466 0.0956
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Schistosoma mansoni biogenic amine (5HT) receptor 0.008 0.0532 0.0822
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0061 0.0274
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.017 0.0411
Schistosoma mansoni zinc finger protein 0.0015 0.003 0.0046
Echinococcus granulosus cathepsin L 0.0034 0.0172 0.0267
Schistosoma mansoni cathepsin F (C01 family) 0.0108 0.0751 0.1162
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0061 0.0138
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0098 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Schistosoma mansoni ran 0.0045 0.0259 0.04
Leishmania major DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Brugia malayi hypothetical protein 0.0029 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Echinococcus granulosus glycine receptor subunit beta 0.0064 0.0404 0.0625
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.008 0.0532 0.0822
Schistosoma mansoni hypothetical protein 0.0062 0.0395 0.0611
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.017 0.0333
Schistosoma mansoni hypothetical protein 0.0062 0.0395 0.0611
Echinococcus granulosus intermediate filament protein 0.0054 0.0327 0.0505
Schistosoma mansoni cpg binding protein 0.0032 0.0162 0.025
Loa Loa (eye worm) hypothetical protein 0.0071 0.0463 0.0463
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0015 0.0029 0.0131
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0133 0.0206
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.017 0.017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.039 0.0603
Echinococcus granulosus dro:myosuppressin receptor 0.008 0.0532 0.0822
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0032 0.0423
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.008 0.0532 0.0822
Plasmodium vivax vivapain-3 0.0064 0.0407 0.5375
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0278 0.043
Schistosoma mansoni Smad4 0.0016 0.0036 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Brugia malayi G protein-coupled receptor 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni amine GPCR 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Plasmodium vivax vivapain-1 0.0064 0.0407 0.5375
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0015 0.0029 0.0011
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0064 0.0404 0.0625
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0132 0.0204
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0498 0.077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.003 0.0145 0.0145
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0029 0.0383
Echinococcus granulosus 7tm_1 domain containing protein 0.008 0.0532 0.0822
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0061 0.0084
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Onchocerca volvulus 0.008 0.0532 0.2937
Mycobacterium ulcerans pyruvate kinase 0.0033 0.017 0.0275
Onchocerca volvulus Putative neutral sphingomyelinase 0.0015 0.0029 0.0011
Leishmania major hypothetical protein, conserved 0.0015 0.0029 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0172 0.0392
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0015 0.0029 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Schistosoma mansoni neuropeptide F-like receptor 0.008 0.0532 0.0822
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0029 0.0011
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0466 0.1274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0309 0.0649
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0395 0.0611
Giardia lamblia Pyruvate kinase 0.0017 0.0044 0.0101
Trypanosoma brucei trypanothione reductase 0.0109 0.0757 0.3415
Schistosoma mansoni adenoreceptor 0.008 0.0532 0.0822
Onchocerca volvulus 0.008 0.0532 0.2937
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0177 0.035
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0015 0.0029 0.0045
Schistosoma mansoni peptide (allatostatin)-like receptor 0.008 0.0532 0.0822
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0015 0.0029 0.0383
Entamoeba histolytica cysteine proteinase 2 0.0064 0.0407 0.5419
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0024 0.0037
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0466 0.1274
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0029 0.0131
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0015 0.0029 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Echinococcus multilocularis cathepsin b 0.0579 0.4407 0.6817
Brugia malayi hypothetical protein 0.0123 0.0864 0.0864
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.2218 1
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0064 0.0404 0.0404
Trypanosoma cruzi cruzipain precursor, putative 0.003 0.0145 0.0276
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0138 0.0138
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.017 0.0386
Giardia lamblia Cathepsin L-like protease 0.0034 0.0172 0.0987
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0231 0.0524
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0153 0.2042
Toxoplasma gondii preprocathepsin c precursor, putative 0.0034 0.0172 0.1163
Echinococcus granulosus peptide allatostatin:somatostatin 0.008 0.0532 0.0822
Echinococcus granulosus cathepsin b 0.0579 0.4407 0.6817
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0061 0.0274
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0176 0.0176
Echinococcus granulosus snurportin 1 0.0651 0.4965 0.7678
Brugia malayi CXXC zinc finger family protein 0.0029 0.0134 0.0134
Schistosoma mansoni biogenic amine receptor 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0361 0.2435
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0206 0.0079
Onchocerca volvulus 0.0072 0.0466 0.2557
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0064 0.0407 0.063
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Onchocerca volvulus 0.0034 0.0176 0.087
Echinococcus multilocularis glycine receptor subunit beta 0.0064 0.0404 0.0625
Brugia malayi Cation transporter family protein 0.0064 0.0404 0.0404
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.0144
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0202 0.1482 0.6683
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0388 0.06
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0029 0.0011
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Echinococcus multilocularis lamin dm0 0.0054 0.0327 0.0505
Plasmodium falciparum serine repeat antigen 7 0.0034 0.0172 0.2277
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0466 0.106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0098 0.0109
Brugia malayi hypothetical protein 0.0029 0.0138 0.0138
Schistosoma mansoni DNA helicase recq5 0.0029 0.0133 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Echinococcus multilocularis neutral sphingomyelinase 0.0015 0.0029 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0015 0.0029 0.0045
Plasmodium falciparum importin beta, putative 0.0061 0.0384 0.5069
Schistosoma mansoni nocturnin 0.0015 0.0029 0.0045
Brugia malayi putative neuropeptide receptor 0.008 0.0532 0.0532
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0029 0.0383
Onchocerca volvulus 0.008 0.0532 0.2937
Echinococcus granulosus g protein coupled receptor 0.008 0.0532 0.0822
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.008 0.0532 0.0822
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.2218 0.5005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0278 0.043
Loa Loa (eye worm) GABA receptor subunit 0.0034 0.0176 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Schistosoma mansoni biogenic amine (dopamine) receptor 0.008 0.0532 0.0822
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Entamoeba histolytica cysteine proteinase, putative 0.0078 0.0517 0.6876
Leishmania major trypanothione reductase 0.0109 0.0757 0.3415
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0029 0.0138 0.0138
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0064 0.0407 0.0925
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.0204 0.0464
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.039 0.0603
Brugia malayi excitatory GABA receptor EXP-1A 0.0064 0.0404 0.0404
Echinococcus multilocularis pyruvate kinase 0.0033 0.017 0.0263
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0259 0.0259
Echinococcus multilocularis alpha 1A adrenergic receptor 0.008 0.0532 0.0822
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0271 0.0418
Echinococcus multilocularis cysteine protease 0.0108 0.0751 0.1162
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0388 0.06
Brugia malayi cathepsin F-like cysteine proteinase 0.003 0.0145 0.0145
Brugia malayi Serotonin receptor 0.008 0.0532 0.0532
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0029 0.0138 0.0214
Echinococcus multilocularis musashi 0.0054 0.0327 0.0505
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0032 0.0009
Loa Loa (eye worm) hypothetical protein 0.0061 0.0384 0.0384
Echinococcus granulosus neutral sphingomyelinase 0.0015 0.0029 0.0045
Loa Loa (eye worm) pyruvate kinase 0.0033 0.017 0.017
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0015 0.0029 0.0131
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0044 0.0295
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0064 0.0404 0.0625
Loa Loa (eye worm) hypothetical protein 0.0434 0.3281 0.3281
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0098 0.0201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0271 0.0418
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0145 0.0224
Echinococcus multilocularis G-protein coupled receptor, putative 0.008 0.0532 0.0822
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0138 0.0138
Echinococcus granulosus somatostatin receptor 0.008 0.0532 0.0822
Echinococcus granulosus neuropeptide receptor A26 0.008 0.0532 0.0822
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0172 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.008 0.0532 0.0532
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0044 0.0068
Brugia malayi Augmenter of liver regeneration 0.0034 0.0177 0.0177
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0138 0.0214
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0032 0.0032
Schistosoma mansoni myosin xvIII 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0044 0.0576
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0064 0.0404 0.0404
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0153 0.0692
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0064 0.0404 0.0625
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0172 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Echinococcus multilocularis neuropeptide Y receptor 0.008 0.0532 0.0822
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.017 0.0832
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0466 0.1009
Toxoplasma gondii cathepsin CPC1 0.0034 0.0172 0.1163
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0064 0.0404 0.0625
Echinococcus granulosus cathepsin l1 0.0078 0.0517 0.0799
Loa Loa (eye worm) RecQ helicase 0.0041 0.0231 0.0231
Plasmodium falciparum cysteine proteinase falcipain 3 0.0108 0.0751 0.9919
Schistosoma mansoni bromodomain containing protein 0.0065 0.0418 0.0646
Brugia malayi G-protein coupled receptor 0.008 0.0532 0.0532
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0172 0.0987
Echinococcus granulosus pyruvate kinase 0.0033 0.017 0.0263
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0015 0.0029 0.0066
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0061 0.0084
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0466 0.2102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Echinococcus multilocularis tachykinin peptides receptor 99D 0.037 0.2786 0.4309
Trypanosoma brucei ISWI complex protein 0.0015 0.003 0.0136
Trichomonas vaginalis ran, putative 0.0045 0.0259 0.0589
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0794 0.2228
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0064 0.0404 0.0404
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0579 0.4407 0.6817
Echinococcus multilocularis nAChR subunit 0.0064 0.0404 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0063
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0034 0.0172 0.2277
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.0204 0.2693
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Plasmodium vivax exodeoxyribonuclease III, putative 0.0015 0.0029 0.0383
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0034 0.0172 0.0267
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0206 0.0416
Echinococcus multilocularis cpg binding protein 0.0032 0.0162 0.025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0498 0.108
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0029 0.0383
Echinococcus granulosus thyrotropin releasing hormone receptor 0.008 0.0532 0.0822
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.0204 0.2693
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Leishmania major hypothetical protein, conserved 0.0015 0.003 0.0136
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0064 0.0404 0.0625
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0172 0.0172
Leishmania major hypothetical protein, conserved 0.0072 0.0466 0.2102
Schistosoma mansoni hypothetical protein 0.0844 0.6466 1
Schistosoma mansoni amine GPCR 0.008 0.0532 0.0822
Brugia malayi Tachykinin-like peptides receptor 99D 0.008 0.0532 0.0532
Plasmodium falciparum cysteine proteinase falcipain 1 0.0064 0.0407 0.5375
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Leishmania major DNA polymerase eta, putative 0.0019 0.0061 0.0274
Echinococcus multilocularis neuropeptide s receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0498 0.108
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0034 0.0172 0.2277
Trypanosoma cruzi cruzipain precursor, putative 0.0108 0.0751 0.1659
Echinococcus granulosus hypothetical protein 0.008 0.0532 0.0822
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.0204 0.1204
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0153 0.0692
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0498 0.6569
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0029 0.0029
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0015 0.0029 0.0386
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0064 0.0404 0.0625
Echinococcus granulosus GPCR family 2 0.0062 0.0395 0.0611
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0117 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0034 0.0176 0.0273
Echinococcus granulosus alpha 1A adrenergic receptor 0.008 0.0532 0.0822
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0064 0.0404 0.0404
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0153 0.0295
Schistosoma mansoni pyruvate kinase 0.0033 0.017 0.0263
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.003 0.0145 0.0145
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.008 0.0532 0.0822
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0204 0.0411
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0579 0.4407 0.6817
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0172 0.2277
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0309 0.2082
Loa Loa (eye worm) hypothetical protein 0.0025 0.0104 0.0104
Plasmodium falciparum thioredoxin reductase 0.0109 0.0757 1
Schistosoma mansoni biogenic amine receptor 0.008 0.0532 0.0822
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0138 0.0138
Onchocerca volvulus Cathepsin L homolog 0.0108 0.0751 0.4215
Echinococcus multilocularis g-protein coupled receptor 0.008 0.0532 0.0822
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0133 0.0899
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0034 0.0176 0.0273
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0109 0.0757 0.2122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Brugia malayi Importin beta-1 subunit 0.0061 0.0384 0.0384
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.0204 0.0353
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0098 0.0109
Echinococcus granulosus nAChR subunit 0.0034 0.0176 0.0273
Onchocerca volvulus 0.0064 0.0404 0.2195
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Onchocerca volvulus 0.008 0.0532 0.2937
Brugia malayi hypothetical protein 0.0241 0.178 0.178
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi larval opioid receptor 0.008 0.0532 0.0532
Schistosoma mansoni growth hormone secretagogue receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0259 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0063
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0172 0.0392
Echinococcus granulosus glycine receptor subunit beta 0.0064 0.0404 0.0625
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0798 0.6106 0.9443
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0407 0.1835
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.008 0.0532 0.0822
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0064 0.0404 0.0625
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0751 0.1659
Echinococcus granulosus lamin dm0 0.0054 0.0327 0.0505
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0032 0.0216
Echinococcus granulosus biogenic amine 5HT receptor 0.008 0.0532 0.0822
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Schistosoma mansoni ran 0.0045 0.0259 0.04
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.5342 0.8263
Brugia malayi G protein-coupled receptor F59B2.13 0.008 0.0532 0.0532
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0064 0.0404 0.0625
Plasmodium vivax thioredoxin reductase, putative 0.0109 0.0757 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.008 0.0532 0.0822
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0204 0.092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0064 0.0407 0.0925
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Loa Loa (eye worm) neuropeptide F receptor 0.008 0.0532 0.0532
Brugia malayi Pre-SET motif family protein 0.0207 0.1516 0.1516
Mycobacterium ulcerans hypothetical protein 0.0024 0.0098 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Echinococcus granulosus cathepsin L cysteine protease 0.0064 0.0407 0.063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0384 0.259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Brugia malayi intermediate filament protein 0.0054 0.0327 0.0327
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0172 0.0172
Schistosoma mansoni nAChR subunit 0.0064 0.0404 0.0625
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0309 0.0649
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0177 0.1198
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0441
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.008 0.0532 0.0822
Trypanosoma brucei unspecified product 0.0013 0.0014 0.0063
Echinococcus granulosus allatostatin A receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0498 0.1028
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Echinococcus granulosus zinc finger protein 0.0021 0.0076 0.0118
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Echinococcus multilocularis cathepsin L 0.0034 0.0172 0.0267
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0395 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0172 0.0392
Loa Loa (eye worm) glutathione reductase 0.0109 0.0757 0.0757
Brugia malayi G-protein coupled receptor 0.008 0.0532 0.0532
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0138 0.0138
Echinococcus granulosus smad 0.0016 0.0036 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0172 0.0172
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0206 0.0469
Brugia malayi Pax transcription factor protein 2 0.0236 0.1745 0.1745
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0014 0.002 0.026
Plasmodium falciparum serine repeat antigen 8 0.0034 0.0172 0.2277
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.008 0.0532 0.0822
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0061 0.0084
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0121
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0395 0.0395
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0133 0.0206
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.004
Mycobacterium ulcerans glutaminase 0.0578 0.4399 1
Leishmania major pyruvate kinase 0.0033 0.017 0.0766
Loa Loa (eye worm) TYRA-2 protein 0.008 0.0532 0.0532
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0172 0.0267
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0177 0.2344
Loa Loa (eye worm) ACC-1 protein 0.0064 0.0404 0.0404
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0034 0.0176 0.0176
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0108 0.0751 0.1162
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0172 0.0172
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0108 0.0751 0.9919
Loa Loa (eye worm) G-protein coupled receptor 0.008 0.0532 0.0532
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0395 0.0611
Plasmodium falciparum serine repeat antigen 3 0.0034 0.0172 0.2277
Echinococcus multilocularis cysteine protease 0.0108 0.0751 0.1162
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0206 0.0469
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0091 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.0204 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0034 0.0172 0.0392
Brugia malayi hypothetical protein 0.0029 0.0138 0.0138
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0029 0.0386
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.1003 0.452
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0064 0.0404 0.0625
Echinococcus granulosus serotonin receptor 0.008 0.0532 0.0822
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0204 0.0411
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) LGC-31 protein 0.0064 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Onchocerca volvulus 0.0235 0.1737 0.9957
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0061 0.0061
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0133 0.0206
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0145 0.0978
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.0751 1
Echinococcus granulosus neuropeptide receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0051 0.0309 0.0309
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0034 0.0172 0.2277
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.1003 0.452
Brugia malayi fibroinase precursor 0.0034 0.0172 0.0172
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0271 0.0271
Schistosoma mansoni hypothetical protein 0.0021 0.0072 0.0111
Onchocerca volvulus 0.0108 0.0751 0.4215
Echinococcus multilocularis cathepsin L 0.0064 0.0407 0.063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.0204 0.0353
Schistosoma mansoni nAChR subunit 0.0029 0.0138 0.0214
Onchocerca volvulus 0.0029 0.0138 0.0647
Schistosoma mansoni cript-related 0.0015 0.0029 0.0045
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0098 0.1303
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Echinococcus granulosus tachykinin peptides receptor 99D 0.037 0.2786 0.4309
Schistosoma mansoni biogenic amine receptor 0.008 0.0532 0.0822
Plasmodium vivax glutathione reductase, putative 0.0109 0.0757 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0579 0.4407 0.6817
Onchocerca volvulus 0.008 0.0532 0.2937
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0032 0.005
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.0051
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.1303
Loa Loa (eye worm) hypothetical protein 0.0062 0.0395 0.0395
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Onchocerca volvulus 0.0064 0.0404 0.2195
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0138 0.0214
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0466 0.0956
Echinococcus multilocularis geminin 0.0844 0.6466 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0064 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0051 0.0667
Echinococcus multilocularis sex peptide receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0034 0.0172 0.0172
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0036 0.0056
Echinococcus multilocularis pyruvate kinase 0.0026 0.0115 0.0178
Echinococcus multilocularis cathepsin b 0.0579 0.4407 0.6817
Schistosoma mansoni DNA helicase recq1 0.0029 0.0133 0.0206
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0034 0.0176 0.0176
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0172 0.0846
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.178 0.2753
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0098 0.0201
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.003 0.0145 0.0145
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0034 0.0172 0.0267
Brugia malayi Cathepsin L-like precursor 0.0108 0.0751 0.0751
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0309 0.4074
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0751 0.1708
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0498 0.6569
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0172 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Loa Loa (eye worm) hypothetical protein 0.0041 0.0229 0.0229
Toxoplasma gondii thioredoxin reductase 0.0109 0.0757 0.511
Onchocerca volvulus 0.0054 0.0327 0.1745
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0441
Plasmodium vivax unspecified product 0.0034 0.0172 0.2277
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0034 0.0172 0.0987
Echinococcus multilocularis rhodopsin orphan GPCR 0.008 0.0532 0.0822
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0015 0.0029 0.0386
Toxoplasma gondii exonuclease III APE 0.0076 0.0498 0.3357
Echinococcus multilocularis serotonin receptor 0.008 0.0532 0.0822
Trypanosoma cruzi cysteine proteinase, putative 0.0064 0.0407 0.0874
Loa Loa (eye worm) hypothetical protein 0.0054 0.0327 0.0327
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0029 0.0045
Schistosoma mansoni biogenic amine (dopamine) receptor 0.008 0.0532 0.0822
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0466 0.1274
Schistosoma mansoni neuropeptide receptor 0.008 0.0532 0.0822
Brugia malayi Cathepsin L-like precursor 0.0078 0.0517 0.0517
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Echinococcus granulosus neuropeptides capa receptor 0.008 0.0532 0.0822
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0259 0.0536
Onchocerca volvulus 0.0034 0.0176 0.087
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0064 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0023 0.0091 0.0091
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0172 0.0172
Entamoeba histolytica cysteine proteinase, putative 0.0064 0.0407 0.5419
Schistosoma mansoni pyruvate kinase 0.0033 0.017 0.0263
Brugia malayi MH1 domain containing protein 0.0016 0.0036 0.0036
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0172 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0043 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0145 0.0276
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.0204 0.0315
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0111 0.0172
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0466 0.0721
Echinococcus granulosus tm gpcr rhodopsin 0.008 0.0532 0.0822
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0061 0.0274
Echinococcus multilocularis lamin 0.0054 0.0327 0.0505
Echinococcus multilocularis zinc finger protein 0.0021 0.0076 0.0118
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0099 0.0154
Echinococcus multilocularis traf and tnf receptor associated protein 0.0015 0.0029 0.0045
Loa Loa (eye worm) ACC-1 protein 0.0064 0.0404 0.0404
Echinococcus granulosus geminin 0.0844 0.6466 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Brugia malayi hypothetical protein 0.0051 0.0309 0.0309
Schistosoma mansoni hypothetical protein 0.0023 0.0089 0.0138
Entamoeba histolytica cysteine proteinase, putative 0.0064 0.0407 0.5419
Trypanosoma brucei pyruvate kinase 1 0.0033 0.017 0.0766
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0235 0.0481
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0032 0.005
Echinococcus granulosus pyruvate kinase 0.0017 0.0044 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0751 0.1708
Giardia lamblia Cathepsin B precursor 0.0034 0.0172 0.0987
Echinococcus multilocularis GPCR, family 2 0.0062 0.0395 0.0611
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0061 0.0061
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0029 0.0386
Onchocerca volvulus 0.008 0.0532 0.2937
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0064 0.0404 0.0625
Loa Loa (eye worm) acetylcholine receptor protein 0.0029 0.0138 0.0138
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.017 0.0333
Brugia malayi glutathione reductase 0.0109 0.0757 0.0757
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.2321 0.2321
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0466 0.1274
Plasmodium falciparum serine repeat antigen 2 0.0034 0.0172 0.2277
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0466 0.106
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0466 0.1274
Brugia malayi Papain family cysteine protease containing protein 0.0064 0.0407 0.0407
Brugia malayi MH2 domain containing protein 0.0237 0.1751 0.1751
Onchocerca volvulus 0.0064 0.0404 0.2195
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0177 0.08
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0235 0.0481
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0202 0.1482 0.3327
Onchocerca volvulus Neuropeptide F receptor homolog 0.008 0.0532 0.2937
Loa Loa (eye worm) melatonin receptor type 1A 0.008 0.0532 0.0532
Brugia malayi Dopamine receptor 0.008 0.0532 0.0532
Schistosoma mansoni smad 0.0016 0.0036 0.0056
Loa Loa (eye worm) hypothetical protein 0.0197 0.1442 0.1442
Echinococcus multilocularis g protein coupled receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) thioredoxin reductase 0.0109 0.0757 0.0757
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0064 0.0404 0.0404
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.008 0.0532 0.0822
Trichomonas vaginalis Phospholipase C precursor, putative 0.0015 0.0029 0.0066
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0015 0.0029 0.0045
Plasmodium vivax unspecified product 0.003 0.0145 0.1916
Giardia lamblia Cathepsin L precursor 0.0034 0.0172 0.0987
Mycobacterium ulcerans hypothetical protein 0.0072 0.0466 0.0956
Brugia malayi follicle stimulating hormone receptor 0.031 0.2321 0.2321
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0109
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0327 0.0327
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0061 0.0274
Loa Loa (eye worm) Smad1 0.0016 0.0036 0.0036
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.1442 0.1442
Onchocerca volvulus Putative nachr subunit 0.0064 0.0404 0.2195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0172 0.0392
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0172 0.0267
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0061 0.0094
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0097 0.0654
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0393 0.0608
Schistosoma mansoni cpg binding protein 0.0029 0.0134 0.0207
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0751 0.1659
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.0751 0.0751
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0133 0.0899
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0029 0.0029
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0044 0.0576
Brugia malayi cathepsin L-like precursor 0.0078 0.0517 0.0517
Echinococcus multilocularis synaptojanin 1 0.0015 0.0029 0.0045
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0034 0.0172 0.2277
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.005
Brugia malayi Cathepsin L-like precursor 0.003 0.0145 0.0145
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0015 0.0029 0.0066
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0133 0.0133
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.008 0.0532 0.0822
Mycobacterium ulcerans lipase LipD 0.0072 0.0466 0.0956
Trichomonas vaginalis esterase, putative 0.0072 0.0466 0.106
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma brucei unspecified product 0.0013 0.0014 0.0063
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0177 0.035
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0101 0.1338
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0064 0.0404 0.0625
Onchocerca volvulus 0.0029 0.0134 0.0623
Entamoeba histolytica cysteine protease, putative 0.0064 0.0407 0.5419
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0064 0.0404 0.0625
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0098
Brugia malayi Cathepsin L-like cysteine proteinase 0.0078 0.0517 0.0517
Giardia lamblia DINP protein human, muc B family 0.0019 0.0061 0.0218
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0029 0.0066
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0327 0.0327
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Loa Loa (eye worm) hypothetical protein 0.0029 0.0138 0.0138
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.008 0.0532 0.0822
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0172
Brugia malayi Cation transporter family protein 0.0064 0.0404 0.0404
Schistosoma mansoni neuropeptide receptor 0.008 0.0532 0.0822
Echinococcus multilocularis pyruvate kinase 0.0017 0.0044 0.0068
Onchocerca volvulus 0.0029 0.0138 0.0647
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0278 0.043
Echinococcus granulosus cathepsin L cysteine proteinase 0.0108 0.0751 0.1162
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0011
Entamoeba histolytica Ran family GTPase 0.0045 0.0259 0.3446
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0231 0.0357
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0133 0.0717
Onchocerca volvulus 0.008 0.0532 0.2937
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0034 0.0176 0.0176
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0036 0.0056
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0309 0.4074
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0579 0.4407 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0751 0.3387
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0061 0.0274
Chlamydia trachomatis pyruvate kinase 0.0033 0.017 0.7786
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0271 0.0418
Brugia malayi beta-lactamase family protein 0.0072 0.0466 0.0466
Brugia malayi Inositol-1 0.0038 0.0206 0.0206
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.008 0.0532 0.0822
Echinococcus multilocularis neuropeptides capa receptor 0.008 0.0532 0.0822
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0498 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0794 0.2228
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0133 0.0133
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0029 0.0029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0141 0.1009 0.2856
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0651 0.4965 0.4965
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0029 0.0011
Onchocerca volvulus 0.0108 0.0751 0.4215
Loa Loa (eye worm) hypothetical protein 0.003 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.026 0.1927 0.1927
Trypanosoma brucei unspecified product 0.0019 0.0061 0.0274
Brugia malayi MH2 domain containing protein 0.0016 0.0036 0.0036
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0259 0.04
Echinococcus granulosus cpg binding protein 0.0032 0.0162 0.025
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0395 0.0395
Onchocerca volvulus 0.008 0.0532 0.2937
Loa Loa (eye worm) hypothetical protein 0.008 0.0532 0.0532
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0388 0.06
Treponema pallidum NADH oxidase 0.0038 0.0204 0.38
Loa Loa (eye worm) cathepsin B 0.0202 0.1482 0.1482
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0204 0.0411
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0072 0.0072
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0177 0.0275
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0133 0.0133
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0451
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0064 0.0404 0.0625
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0202 0.1482 0.337
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0061 0.0092
Echinococcus granulosus tar DNA binding protein 0.0061 0.0388 0.06
Mycobacterium ulcerans beta-lactamase 0.0072 0.0466 0.0956
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0388 0.06
Leishmania major cathepsin L-like protease 0.0108 0.0751 0.3387
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0029 0.0066
Leishmania major hypothetical protein, conserved 0.0015 0.0029 0.0131
Brugia malayi cathepsin B-like cysteine proteinase 0.0579 0.4407 0.4407
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0172 0.0267
Brugia malayi hypothetical protein 0.008 0.0532 0.0532
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0061 0.0094
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0294 0.0669
Echinococcus granulosus biogenic amine 5HT receptor 0.008 0.0532 0.0822
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0064 0.0404 0.0404
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.1751 0.1751
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0133 0.0133
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0176 0.0176
Onchocerca volvulus 0.008 0.0532 0.2937
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0441
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0064 0.0404 0.0404
Onchocerca volvulus Cathepsin F homolog 0.0108 0.0751 0.4215
Loa Loa (eye worm) hypothetical protein 0.0123 0.0864 0.0864
Entamoeba histolytica cysteine protease, putative 0.0034 0.0172 0.2295
Onchocerca volvulus 0.0236 0.1745 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0032 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0751 0.1659
Schistosoma mansoni neutral sphingomyelinase 0.0015 0.0029 0.0045
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0466 0.4042
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0327 0.0327
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0466 0.106
Schistosoma mansoni lamin 0.0054 0.0327 0.0505
Echinococcus granulosus nAChR subunit 0.0064 0.0404 0.0625
Schistosoma mansoni cathepsin s 0.003 0.0145 0.0224
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.0204 0.2693
Schistosoma mansoni inositol monophosphatase 0.0038 0.0206 0.0319
Schistosoma mansoni hypothetical protein 0.0651 0.4965 0.7678
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0498 0.1131
Loa Loa (eye worm) hypothetical protein 0.0072 0.0466 0.0466
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.008 0.0532 0.0532
Brugia malayi GnHR receptor homolog 0.008 0.0532 0.0532
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0029 0.0131
Echinococcus granulosus g protein coupled receptor 0.008 0.0532 0.0822
Onchocerca volvulus Huntingtin homolog 0.0123 0.0864 0.4871
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0133 0.0133
Brugia malayi MH1 domain containing protein 0.0016 0.0036 0.0036
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.0204 0.0464

Activities

Activity type Activity value Assay description Source Reference
Efficacy (functional) = 14 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha5-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (functional) = 14 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha5-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 15 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha5-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (binding) = 15 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha5-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 15 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha5-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (binding) = 15 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha5-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (functional) = 35 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha2-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (functional) = 35 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha2-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 36 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha2-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (binding) = 36 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha2-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 36 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha2-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (binding) = 36 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha2-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 44 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha3-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (functional) = 44 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha3-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 44 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha3-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 44 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha3-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (functional) = 44 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha3-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 44 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha3-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 53 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha1-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (functional) = 53 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha1-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 53 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha1-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Efficacy (binding) = 53 % Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha1-beta3-gamma2 subunits ChEMBL. 15084116
Efficacy (functional) = 53 % Percent change in electrophysiological response in Xenopus oocytes expressing Alpha1-beta3-gamma2 GABA-A receptor ChEMBL. 15214791
Efficacy (binding) = 53 % Efficacy of the compound was measured as modulation of the current in response to GABA at hGABA alpha1-beta3-gamma2 receptor expressed in Xenopus oocytes ChEMBL. 15743180
Ki (binding) = 2.6 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 2.6 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 2.9 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha5-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 2.9 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha5-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 3 nM Binding affinity towards human alpha5-beta3-gamma2 GABA-A receptor using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 3 nM Binding affinity towards human alpha5-beta3-gamma2 GABA-A receptor using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 20 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 20 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 23.7 nM Binding affinity towards human gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 23.7 nM Binding affinity towards human gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 25 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha3-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 25 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha3-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 36 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric acid A receptor alpha2-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 36 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric acid A receptor alpha2-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 44.5 nM Binding affinity towards human gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 44.5 nM Binding affinity towards human gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 46 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha2-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 46 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha2-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 122.2 nM Binding affinity towards human alpha1-beta3-gamma2 GABA-A receptor using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 122.2 nM Binding affinity towards human alpha1-beta3-gamma2 GABA-A receptor using [3H]-Ro-15-1788 expressed in L(tk-) cells ChEMBL. 15214791
Ki (binding) = 160 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 160 nM Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 subtype expressed in L (tk-) cells ChEMBL. 15743180
Ki (binding) = 170 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha1-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116
Ki (binding) = 170 nM Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha1-beta3-gamma2 receptor subunits expressed in Xenopus oocytes ChEMBL. 15084116

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.