Detailed information for compound 1181180

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 346.346 | Formula: C19H17F3N2O
  • H donors: 2 H acceptors: 2 LogP: 4.18 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C(c1[nH]cc(n1)c1cccc(c1)C(F)(F)F)O)C
  • InChi: 1S/C19H17F3N2O/c1-11-6-7-12(2)15(8-11)17(25)18-23-10-16(24-18)13-4-3-5-14(9-13)19(20,21)22/h3-10,17,25H,1-2H3,(H,23,24)
  • InChiKey: VAQBKXHPOYWRNU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0095 0.0376
Echinococcus granulosus solute carrier family 22 0.0016 0.0018 0.0018
Brugia malayi latrophilin 2 splice variant baaae 0.0284 0.1477 0.4597
Echinococcus multilocularis pyruvate kinase 0.0018 0.0033 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0938 0.2919
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0448 0.1393
Onchocerca volvulus 0.0016 0.0018 0.0055
Brugia malayi Bromodomain containing protein 0.0029 0.009 0.0281
Brugia malayi hypothetical protein 0.0018 0.0032 0.0099
Toxoplasma gondii facilitative glucose transporter GT1 0.0112 0.0539 0.3261
Onchocerca volvulus 0.0016 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0049 0.0049
Trichomonas vaginalis esterase, putative 0.004 0.0149 0.0461
Loa Loa (eye worm) hypothetical protein 0.0516 0.2735 0.8512
Brugia malayi Cytochrome P450 family protein 0.0057 0.0241 0.075
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0053 0.0219 0.0682
Brugia malayi MH2 domain containing protein 0.0018 0.0033 0.0103
Brugia malayi major facilitator superfamily protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0049 0.0049
Brugia malayi RasGEF domain containing protein 0.0013 0.0003 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0355 0.1412
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0032 0.0032
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0024 0.0024
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.007 0.1969
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0045 0.018 0.4592
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0049 0.0049
Echinococcus multilocularis neuropeptide receptor A26 0.1051 0.5641 0.5641
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 1
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0014 0.0008 0.0035
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0033 0.0129
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0101 0.0482 0.1499
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0115 0.0356
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0127 0.0395
Schistosoma mansoni survival motor neuron protein 0.0105 0.0504 0.0504
Echinococcus multilocularis solute carrier family 22 0.0016 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0049 0.0153
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.02 0.02
Brugia malayi MH1 domain containing protein 0.0018 0.0033 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Brugia malayi Methyltransferase-like protein 4 0.0017 0.0025 0.0079
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0159 0.0796 0.8431
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0032 0.0097
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0604 0.3213 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus granulosus pyruvate kinase 0.0036 0.0127 0.0127
Echinococcus multilocularis ras GTP exchange factor 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.034 0.1777 0.1777
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0796 0.2476
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0348 0.1084
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.02 0.2115
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0036 0.0378
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0003 0.0011
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.02 0.0793
Onchocerca volvulus Huntingtin homolog 0.0133 0.0653 0.203
Plasmodium vivax hypothetical protein, conserved 0.0029 0.009 0.0358
Brugia malayi nuclear hormone receptor 0.0021 0.0049 0.0153
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0944 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0126 0.0501
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0276 0.1432 0.1432
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.015 0.0465
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0055 0.023 0.1044
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0126 0.0501
Mycobacterium tuberculosis Probable integral membrane protein 0.0021 0.0046 0.021
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.02 0.0623
Loa Loa (eye worm) hypothetical protein 0.0101 0.0482 0.15
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0149 0.0149
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 1
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0032 0.0032
Schistosoma mansoni ran 0.0023 0.006 0.006
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.006 0.0187
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0604 0.3213 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0049 0.0049
Echinococcus multilocularis X box binding protein 1 0.0309 0.1612 0.1612
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0604 0.3213 1
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0796 0.2476
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0056 0.0239 0.6123
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.02 0.2115
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0001 0.0002
Brugia malayi beta-lactamase 0.004 0.0149 0.0463
Entamoeba histolytica hypothetical protein 0.004 0.0149 0.0461
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0095 0.024
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0796 0.0796
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0018 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Echinococcus multilocularis L aminoadipate semialdehyde 0.009 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0078 0.0355 0.1105
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0033 0.0033
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0115 0.0357
Entamoeba histolytica Ran family GTPase 0.0023 0.006 0.0186
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0018 0.0192
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0095 0.0574
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0149
Brugia malayi hypothetical protein 0.004 0.0149 0.0462
Onchocerca volvulus 0.0053 0.0219 0.0681
Schistosoma mansoni loxhd1 0.0021 0.0049 0.0049
Toxoplasma gondii sugar transporter ST2 0.0016 0.0018 0.011
Loa Loa (eye worm) beta-lactamase 0.004 0.0149 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Brugia malayi hypothetical protein 0.0016 0.0018 0.0056
Echinococcus granulosus pyruvate kinase 0.0018 0.0033 0.0033
Onchocerca volvulus 0.0013 0.0003 0.0009
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0355 0.0355
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0121 0.128
Brugia malayi Calcitonin receptor-like protein seb-1 0.0416 0.2192 0.6822
Schistosoma mansoni hypothetical protein 0.0309 0.1612 0.1612
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0149 0.0675
Onchocerca volvulus 0.0021 0.0049 0.015
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0159 0.0796 0.2477
Schistosoma mansoni ras GTP exchange factor 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0132 0.0648 0.0648
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0032 0.0099
Schistosoma mansoni dishevelled 0.0018 0.0032 0.0032
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0115 0.0115
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0461
Brugia malayi hypothetical protein 0.0021 0.0049 0.0152
Trypanosoma cruzi ISWI complex protein 0.0014 0.0007 0.0076
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 0.1105
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0018 0.0029 0.0133
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0018 0.0018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0127 0.3254
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0132 0.0648 0.0648
Onchocerca volvulus 0.0016 0.0018 0.0055
Leishmania major pyruvate kinase 0.0036 0.0127 0.135
Mycobacterium ulcerans hypothetical protein 0.0021 0.0046 0.0144
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0078 0.031
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0149 0.0675
Brugia malayi Sugar transporter family protein 0.0016 0.0018 0.0056
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0126 0.0393
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.006 0.0364
Echinococcus multilocularis survival motor neuron protein 1 0.0516 0.2735 0.2734
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0101 0.0482 0.0482
Schistosoma mansoni protein kinase 0.0036 0.0126 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0796 0.2476
Brugia malayi isocitrate dehydrogenase 0.0049 0.02 0.0621
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Schistosoma mansoni inositol monophosphatase 0.004 0.015 0.015
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0121 0.128
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0025 0.0077
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0048 0.0217
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0003 0.0009
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.02 0.02
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0073 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0049 0.0153
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0121 0.0375
Trypanosoma cruzi hexose transporter 0.0035 0.0121 0.128
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0109 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0034 0.0034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0049 0.0049
Plasmodium falciparum importin beta, putative 0.0032 0.0106 0.0419
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.007 0.0745
Schistosoma mansoni glucose transport protein 0.0112 0.0539 0.0539
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0068 0.0068
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.021 0.0952
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0068 0.0413
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.021 0.021
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0049 0.0153
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0001 0.0003
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0127 0.0397
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.015 0.0465
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0056 0.0235 0.2487
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0418 0.2202 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0112 0.0539 0.0539
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.015 0.0465
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 0.1412
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0126 0.0391
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0099
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0355 0.0355
Leishmania major importin beta-1 subunit, putative 0.0026 0.0073 0.0774
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0032 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0149 0.1575
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0127 0.0395
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0186 0.0944 0.2937
Brugia malayi hypothetical protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0033 0.0103
Echinococcus granulosus survival motor neuron protein 1 0.0516 0.2735 0.2734
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0239 0.0745
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0463
Toxoplasma gondii ABC1 family protein 0.004 0.0149 0.09
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0186 0.0944 0.2937
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0049 0.0049
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0241 0.075
Loa Loa (eye worm) hypothetical protein 0.0133 0.0653 0.2031
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.02 0.02
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0021 0.0046 0.021
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0126 0.0764
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Entamoeba histolytica hypothetical protein 0.004 0.0149 0.0461
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0448 0.0448
Plasmodium falciparum zinc finger protein, putative 0.0015 0.0016 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0348 0.0348
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0014 0.001 0.0031
Brugia malayi jmjC domain containing protein 0.0095 0.0448 0.1396
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0049 0.0049
Onchocerca volvulus 0.0016 0.0018 0.0055
Schistosoma mansoni hypothetical protein 0.0182 0.0921 0.0921
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0101 0.0482 0.5106
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0013 0.0003 0.0003
Schistosoma mansoni coup transcription factor 0.0021 0.0049 0.0049
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0068 0.1744
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0056 0.0239 0.0745
Echinococcus granulosus mitogen activated protein kinase 3 0.0159 0.0796 0.0796
Brugia malayi RasGEF domain containing protein 0.0013 0.0003 0.0011
Echinococcus granulosus importin subunit beta 1 0.0032 0.0106 0.0106
Brugia malayi hypothetical protein 0.0021 0.0049 0.0152
Onchocerca volvulus 0.0016 0.0018 0.0055
Mycobacterium ulcerans thioesterase TesA 0.0047 0.0188 0.0586
Schistosoma mansoni hypothetical protein 0.0025 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0132 0.0648 0.0648
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0018 0.0056
Echinococcus granulosus neuropeptide s receptor 0.1051 0.5641 0.5641
Leishmania major hypothetical protein, conserved 0.0016 0.0018 0.0192
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0235 0.2487
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0115 0.0357
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0126 0.0393
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0461
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0126 0.0501
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Schistosoma mansoni lipoxygenase 0.0128 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0049 0.0153
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0115 0.0356
Mycobacterium tuberculosis Conserved protein 0.0017 0.0025 0.0115
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0033
Echinococcus granulosus RUN 0.0021 0.0049 0.0049
Schistosoma mansoni sugar transporter 0.0016 0.0018 0.0018
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0013 0.0003 0.0036
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0003 0.0003
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0003 0.0003
Schistosoma mansoni protein kinase 0.0036 0.0126 0.0126
Echinococcus granulosus peregrin 0.0029 0.009 0.009
Entamoeba histolytica hypothetical protein 0.004 0.0149 0.0461
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0023 0.0057 0.0258
Loa Loa (eye worm) hypothetical protein 0.0033 0.0115 0.0357
Trypanosoma brucei CAAX amino terminal protease, putative 0.0101 0.0482 0.5106
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0121 0.0375
Loa Loa (eye worm) sugar transporter 0.0112 0.0539 0.1677
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0121 0.0375
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0355 0.2149
Echinococcus multilocularis peregrin 0.0029 0.009 0.009
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0095 0.0294
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.007 0.0426
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0018 0.0192
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus GPCR family 2 0.0132 0.0648 0.0648
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.0107 0.0107
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0152 0.0152
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0448 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0018 0.0055
Toxoplasma gondii hypothetical protein 0.0027 0.0078 0.0474
Loa Loa (eye worm) hypothetical protein 0.009 0.0421 0.1311
Schistosoma mansoni rab6-interacting 0.0021 0.0049 0.0049
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0068 0.0068
Echinococcus granulosus mitogen activated protein kinase 0.0159 0.0796 0.0796
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0121 0.0375
Mycobacterium ulcerans polyketide synthase MbtC 0.0014 0.001 0.0031
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0033 0.0129
Echinococcus multilocularis Smad4 0.0018 0.0033 0.0033
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.021 0.5363
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0018 0.0192
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0018 0.0192
Entamoeba histolytica hypothetical protein 0.0025 0.007 0.0217
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0448 0.0448
Mycobacterium leprae Probable lipase LipE 0.004 0.0149 0.3804
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0036
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0078 0.104
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0121 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0014 0.001 0.001
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.02 0.1208
Schistosoma mansoni multidrug resistance protein 0.0012 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0235 0.0933
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0326
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0068 0.0212
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0145 0.1534
Mycobacterium ulcerans integral membrane protein 0.0021 0.0046 0.0144
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0018 0.0018
Mycobacterium tuberculosis Hypothetical protein 0.0017 0.0025 0.0115
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0127 0.0395
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0049 0.0049
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Schistosoma mansoni smad 0.0018 0.0033 0.0033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0109 0.0109
Onchocerca volvulus 0.0604 0.3213 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0448 0.0448
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0126 0.0764
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0073 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0049 0.0153
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.006 0.0258 0.661
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0068 0.0068
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0003 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0049 0.0153
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0149 0.0463
Leishmania major GTP-binding protein, putative 0.0023 0.006 0.0637
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0049 0.0049
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0145 0.0876
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0604 0.3213 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.015 0.0465
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Leishmania major hypothetical protein, conserved 0.0017 0.0025 0.0267
Onchocerca volvulus 0.0098 0.0466 0.145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0448 0.0448
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0448 0.0448
Echinococcus granulosus L aminoadipate semialdehyde 0.009 0.0421 0.0421
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.007 0.0745
Brugia malayi ecdysteroid receptor 0.0021 0.0049 0.0153
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0014 0.001 0.001
Brugia malayi nuclear receptor NHR-88 0.0021 0.0049 0.0153
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0024 0.0024
Brugia malayi N-terminal motif family protein 0.0013 0.0003 0.0011
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0186 0.0944 1
Schistosoma mansoni importin beta-1 0.0032 0.0106 0.0106
Brugia malayi CAAX amino terminal protease family protein 0.0101 0.0482 0.15
Loa Loa (eye worm) hypothetical protein 0.005 0.0203 0.0631
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0068 0.027
Plasmodium falciparum protease, putative 0.0021 0.0046 0.0182
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.015 0.0907
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0018 0.0056
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.0887 0.2759
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0145 0.0575
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0016 0.0018 0.0082
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0068 0.0212
Schistosoma mansoni cpg binding protein 0.013 0.064 0.064
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0049 0.0049
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0014 0.001 0.006
Schistosoma mansoni cpg binding protein 0.0138 0.068 0.068
Echinococcus multilocularis son of sevenless 1 0.0013 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0049 0.0153
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Brugia malayi Doublecortin family protein 0.0021 0.0049 0.0152
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0049 0.0153
Loa Loa (eye worm) hypothetical protein 0.0132 0.0648 0.2016
Echinococcus multilocularis solute carrier family 22 0.0016 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0049 0.0153
Brugia malayi Cam kinase protein 1 0.0036 0.0126 0.0393
Loa Loa (eye worm) hypothetical protein 0.0033 0.0115 0.0357
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0159 0.0796 0.8431
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Brugia malayi Flap endonuclease-1 0.003 0.0095 0.0295
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0095 0.0295
Onchocerca volvulus 0.0016 0.0018 0.0055
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0068 0.0722
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0055 0.023 0.1044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Loa Loa (eye worm) fatty acid synthase 0.0056 0.0235 0.0732
Loa Loa (eye worm) hypothetical protein 0.037 0.194 0.604
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0013 0.0003 0.0009
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0033 0.0198
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0675
Leishmania major glucose transporter, lmgt3 0.0035 0.0121 0.128
Schistosoma mansoni glucose transport protein 0.0112 0.0539 0.0539
Trypanosoma brucei glucose transporter 2A 0.0035 0.0121 0.128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0049 0.0153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0011
Entamoeba histolytica protein kinase, putative 0.0036 0.0126 0.0391
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.015 0.1588
Brugia malayi hypothetical protein 0.0016 0.0018 0.0056
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0159 0.0796 0.8431
Onchocerca volvulus 0.009 0.0421 0.131
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0049 0.0153
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0127 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0121 0.0375
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0049 0.0152
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0049 0.0153
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.02 0.0793
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0126 0.0501
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.015 0.1588
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0132 0.0648 0.0648
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0014 0.001 0.0264
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0049 0.0049
Onchocerca volvulus 0.004 0.0149 0.0461
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Brugia malayi hypothetical protein 0.0018 0.0032 0.0099
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0219 0.0682
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0049 0.0049
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0016 0.0018 0.0082
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0084 0.0391 0.1775
Echinococcus multilocularis smad 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.0251
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0032 0.0032
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0084 0.0391 0.1775
Loa Loa (eye worm) acyl carrier protein 0.0026 0.0074 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0019 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0796 0.2476
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0604 0.3213 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.009 0.0281
Mycobacterium ulcerans polyketide synthase 0.006 0.0258 0.0804
Schistosoma mansoni sugar transporter 0.0016 0.0018 0.0018
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0014 0.001 0.0037
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.02 0.02
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0095 0.1005
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0073 0.0774
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0049 0.0192
Toxoplasma gondii hypothetical protein 0.0018 0.0032 0.0192
Echinococcus granulosus snurportin 1 0.034 0.1777 0.1777
Onchocerca volvulus 0.0016 0.0018 0.0055
Brugia malayi MH2 domain containing protein 0.0018 0.0033 0.0103
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0047 0.0188 0.4817
Brugia malayi Inositol-1 0.004 0.015 0.0467
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0056 0.0239 0.1087
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0014 0.001 0.0031
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0018 0.0029 0.0747
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0182 0.092 0.5566
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0068 0.0211
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0014 0.001 0.0104
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0017 0.0027 0.0123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Mycobacterium ulcerans polyketide synthase 0.0056 0.0239 0.0745
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0028 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0018 0.0055
Schistosoma mansoni hypothetical protein 0.0112 0.0539 0.0539
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus X box binding protein 1 0.0309 0.1612 0.1612
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0126 0.0126
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.009 0.009
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0032 0.0032
Brugia malayi hypothetical protein 0.0056 0.0235 0.0731
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0049 0.0049
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.006 0.0237
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0355 0.2149
Loa Loa (eye worm) hypothetical protein 0.0056 0.0235 0.0731
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.037 0.194 0.6039
Schistosoma mansoni hypothetical protein 0.0132 0.0648 0.0648
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0056 0.0239 0.0745
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.0213
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0149 0.0149
Loa Loa (eye worm) transcription factor SMAD2 0.0271 0.1402 0.4365
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0052 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0049 0.0153
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0013 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0271 0.1402 0.4365
Mycobacterium ulcerans polyketide synthase MbtD 0.0017 0.0027 0.0085
Brugia malayi PHD-finger family protein 0.0029 0.009 0.0281
Echinococcus granulosus son of sevenless 1 0.0013 0.0003 0.0003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.02 0.02
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.02 0.2115
Giardia lamblia Pyruvate kinase 0.0018 0.0033 0.0046
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0348 0.1084
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0049 0.0049
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0675
Echinococcus multilocularis Protein son of sevenless 0.0013 0.0003 0.0003
Brugia malayi Isocitrate dehydrogenase 0.0049 0.02 0.0621
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0463
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0258 0.0803
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0126 0.0501
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0149 0.0675
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Giardia lamblia Pyruvate kinase 0.0036 0.0127 0.0342
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0448 0.0448
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0037 0.0136 0.0422
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.1575
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0093 0.0288
Onchocerca volvulus 0.004 0.0149 0.0461
Brugia malayi hypothetical protein 0.0133 0.0653 0.2031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0095 0.0448 0.1393
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0127 0.0397
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0107 0.0514 0.1599
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0049 0.0153
Schistosoma mansoni hypothetical protein 0.0021 0.0049 0.0049
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0105 0.0504 0.157
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0416 0.2192 0.6822
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0018 0.0018
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Leishmania major p-glycoprotein 0.0012 0.0001 0.0005
Mycobacterium tuberculosis Polyketide synthase Pks12 0.006 0.0258 0.1173
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0018 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Mycobacterium leprae Polyketide synthase Pks13 0.0084 0.0391 1
Schistosoma mansoni multidrug resistance protein 0.0012 0.0001 0.0001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0159 0.0796 0.8431
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0049 0.0049
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0018 0.0018
Mycobacterium ulcerans beta-lactamase 0.004 0.0149 0.0463
Mycobacterium ulcerans lipase LipD 0.004 0.0149 0.0463
Schistosoma mansoni inositol monophosphatase 0.004 0.015 0.015
Mycobacterium ulcerans hypothetical protein 0.004 0.0149 0.0463
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0068 0.0068
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0032 0.0099
Brugia malayi steroid hormone receptor 0.0021 0.0049 0.0153
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0068 0.0722
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0126 0.0501
Schistosoma mansoni hypothetical protein 0.0132 0.0648 0.0648
Entamoeba histolytica CAAX amino terminal protease family 0.0021 0.0046 0.0142
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.015 0.1588
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0018 0.0056
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0013 0.0003 0.0009
Echinococcus multilocularis pyruvate kinase 0.0018 0.0033 0.0033
Leishmania major lysyl-tRNA synthetase, putative 0.0025 0.0068 0.0722
Echinococcus granulosus inositol monophosphatase 1 0.004 0.015 0.015
Echinococcus multilocularis pyruvate kinase 0.0036 0.0127 0.0127
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0021 0.0046 0.021
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0145 0.1534
Schistosoma mansoni ran 0.0023 0.006 0.006
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0152 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0049 0.0153
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1586 0.8543 0.8543
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0014 0.001 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Mycobacterium ulcerans thioesterase 0.0047 0.0188 0.0586
Brugia malayi TAR-binding protein 0.0076 0.0348 0.1084
Onchocerca volvulus Putative transporter 0.0016 0.0018 0.0055
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0013 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0127 0.0395
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0036
Echinococcus multilocularis mitogen activated protein kinase 3 0.0159 0.0796 0.0796
Leishmania major glucose transporter, lmgt2 0.0035 0.0121 0.128
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0448 0.1393
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0239 0.0745
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0342 0.0342
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.009 0.0547
Entamoeba histolytica hypothetical protein 0.0015 0.0016 0.0049
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0049 0.0153
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0132 0.0648 0.0648
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0121 0.0375
Brugia malayi follicle stimulating hormone receptor 0.0461 0.2435 0.7579
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.007 0.0779
Brugia malayi DIX domain containing protein 0.0018 0.0032 0.0099
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0235 0.1421
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0106 0.0106
Echinococcus multilocularis solute carrier family 22 0.0016 0.0018 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0049 0.0049
Echinococcus multilocularis mitogen activated protein kinase 0.0159 0.0796 0.0796
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0149 0.0149
Schistosoma mansoni glucose transporter 0.0016 0.0018 0.0018
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.006 0.0258 0.1173
Giardia lamblia Methyltransferase like 2 0.0017 0.0025 0.0022
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0049 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.006 0.0258 0.0804
Onchocerca volvulus 0.0021 0.0049 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0944 1
Echinococcus multilocularis snurportin 1 0.034 0.1777 0.1777
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0101 0.0482 0.5106
Plasmodium falciparum mitogen-activated protein kinase 2 0.0182 0.092 0.366
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0068 0.0212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0604 0.3213 1
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0018 0.007
Onchocerca volvulus 0.0016 0.0018 0.0055
Leishmania major hypothetical protein, conserved 0.004 0.0149 0.1575
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0132 0.0648 0.0648
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0355 0.9084
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.034 0.1777 0.5532
Leishmania major glucose transporter, lmgt1 0.0035 0.0121 0.128
Echinococcus multilocularis General substrate transporter 0.0096 0.0454 0.0454
Schistosoma mansoni myst-related protein 0.0015 0.0016 0.0016
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.007 0.1751
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0127 0.0579
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.007 0.0219
Schistosoma mansoni microtubule-associated protein tau 0.1425 0.7671 0.7671
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0056 0.0239 0.1087
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0018 0.0055
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0115 0.0115
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0348 0.0348
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0604 0.3213 1
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0009
Echinococcus multilocularis RUN 0.0021 0.0049 0.0049
Trypanosoma brucei ISWI complex protein 0.0014 0.0007 0.0076
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0018 0.0056
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0037 0.0136 0.3468
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0018 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0049 0.0153
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0123 0.0123
Echinococcus granulosus pyruvate kinase 0.0036 0.0127 0.0127
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0056 0.0239 0.1087
Schistosoma mansoni Smad4 0.0018 0.0033 0.0033
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0018 0.0055
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0127 0.326
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0073 0.0226
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0164 0.051
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Onchocerca volvulus Huntingtin homolog 0.0133 0.0653 0.203
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Toxoplasma gondii sugar transporter ST1 0.0016 0.0018 0.011
Schistosoma mansoni smdr2 0.0012 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0099
Brugia malayi PHD-finger family protein 0.0017 0.0025 0.0077
Brugia malayi Importin beta-1 subunit 0.0032 0.0106 0.0329
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0115 0.0115
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.021 0.0952
Onchocerca volvulus 0.0016 0.0018 0.0055
Onchocerca volvulus 0.0018 0.0032 0.0097
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0049 0.0049
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0021
Entamoeba histolytica Flap nuclease, putative 0.003 0.0095 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0106 0.112
Plasmodium falciparum flap endonuclease 1 0.003 0.0095 0.0376
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.006 0.006
Mycobacterium ulcerans hypothetical protein 0.0021 0.0046 0.0144
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0013 0.0003 0.0003
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0239 0.0745
Loa Loa (eye worm) histone methyltransferase 0.004 0.0152 0.0472
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0149 0.0463
Mycobacterium leprae conserved hypothetical protein 0.0025 0.007 0.1799
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0126 0.0501
Echinococcus multilocularis flap endonuclease 1 0.003 0.0095 0.0095
Schistosoma mansoni sugar transporter 0.0016 0.0018 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0018 0.0056
Echinococcus multilocularis pyruvate kinase 0.0028 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0018 0.0055
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0078 0.031
Loa Loa (eye worm) glutaminase 2 0.0268 0.139 0.4325
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.015 0.0467
Brugia malayi Sugar transporter family protein 0.0016 0.0018 0.0056
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0068 0.027
Schistosoma mansoni pyruvate kinase 0.0036 0.0127 0.0127
Echinococcus multilocularis microtubule associated protein 2 0.1425 0.7671 0.7671
Echinococcus granulosus Protein son of sevenless 0.0013 0.0003 0.0003
Echinococcus granulosus pyruvate kinase 0.0018 0.0033 0.0033
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.009 0.009
Echinococcus granulosus neuropeptide receptor A26 0.1051 0.5641 0.5641
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0049 0.0049
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.007 0.0426
Trichomonas vaginalis glutaminase, putative 0.0268 0.139 0.4324
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0149 0.0149
Echinococcus granulosus cpg binding protein 0.0138 0.068 0.068
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0032 0.0032
Mycobacterium ulcerans polyketide synthase Pks9 0.0037 0.0136 0.0422
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.006 0.0187
Loa Loa (eye worm) hypothetical protein 0.0416 0.2192 0.6822
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0121 0.128
Plasmodium vivax protease, putative 0.0021 0.0046 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0046 0.021
Mycobacterium ulcerans glutaminase 0.0268 0.139 0.4325
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Brugia malayi hypothetical protein 0.0516 0.2735 0.8512
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.021 0.021
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0159 0.0796 0.8431
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0126 0.0764
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0115 0.0302
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0149 0.0463
Schistosoma mansoni hypothetical protein 0.004 0.0149 0.0149
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0604 0.3213 1
Mycobacterium ulcerans polyketide synthase Pks13 0.0084 0.0391 0.1217
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0049 0.0049
Schistosoma mansoni sugar transporter 0.0016 0.0018 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.006 0.0637
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0149 0.0675
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0032 0.0032
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0017 0.0028 0.0107
Schistosoma mansoni polycystin 1-related 0.0021 0.0049 0.0049
Leishmania major hypothetical protein, conserved 0.0186 0.0944 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0099
Plasmodium vivax CDK-related protein kinase 6, putative 0.0475 0.2512 1
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0127 0.0397
Schistosoma mansoni hypothetical protein 0.0029 0.009 0.009
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0068 0.0068
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0049 0.0049
Brugia malayi MH2 domain containing protein 0.0271 0.1402 0.4365
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0088 0.0531
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0037 0.0132 0.0797
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0001 0.0002
Brugia malayi Sugar transporter family protein 0.0112 0.0539 0.1677
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0049 0.0049
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.009 0.0421 0.1311
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.02 0.0621
Schistosoma mansoni hypothetical protein 0.0182 0.0921 0.0921
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0604 0.3213 1
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0032 0.0032
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0048 0.1223
Schistosoma mansoni glucose transport protein 0.0112 0.0539 0.0539
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0101 0.0482 0.0482
Toxoplasma gondii protein kinase, putative 0.0317 0.1652 1
Echinococcus granulosus geminin 0.0182 0.0921 0.0921
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Chlamydia trachomatis hypothetical protein 0.0021 0.0046 0.129
Loa Loa (eye worm) hypothetical protein 0.0133 0.0653 0.2031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0164 0.0164
Onchocerca volvulus 0.0016 0.0018 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0068 0.0212
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0348 0.0348
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Echinococcus granulosus flap endonuclease 1 0.003 0.0095 0.0095
Echinococcus granulosus General substrate transporter 0.0096 0.0454 0.0454
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.02 0.1208
Brugia malayi RasGEF domain containing protein 0.0013 0.0003 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0049 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0164 0.0164
Schistosoma mansoni cpg binding protein 0.0138 0.068 0.068
Schistosoma mansoni rab6-interacting 0.0021 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0152
Brugia malayi MH1 domain containing protein 0.0018 0.0033 0.0103
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0127 0.0771
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0182 0.092 0.366
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0049 0.0153
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0348 0.0348
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.006 0.0637
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0049 0.0153
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0149 0.0675
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0032 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0032 0.0099
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0014 0.001 0.0037
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.007 0.0219
Schistosoma mansoni multidrug resistance protein 0.0012 0.0001 0.0001
Toxoplasma gondii sugar transporter ST3 0.0016 0.0018 0.011
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0604 0.3213 1
Onchocerca volvulus 0.0016 0.0018 0.0055
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0109 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0033 0.0033
Brugia malayi ABC transporter family protein 0.0012 0.0001 0.0002
Schistosoma mansoni glutaminase 0.0268 0.139 0.139
Plasmodium falciparum hexose transporter 0.0112 0.0539 0.2143
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0018 0.011
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0106 0.064
Onchocerca volvulus 0.0105 0.0504 0.1569
Echinococcus granulosus pyruvate kinase 0.0018 0.0033 0.0033
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0145 0.1534
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Loa Loa (eye worm) inositol-1 0.004 0.015 0.0467
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0032 0.0099
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0045 0.018 0.0559
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0049 0.0049
Onchocerca volvulus 0.004 0.0149 0.0461
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0018 0.024
Brugia malayi Latrophilin receptor protein 2 0.0132 0.0648 0.2016
Schistosoma mansoni hypothetical protein 0.0284 0.1477 0.1477
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0355 0.0355
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0348 0.0348
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0235 0.0933
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Brugia malayi CXXC zinc finger family protein 0.013 0.064 0.1992
Loa Loa (eye worm) latrophilin receptor protein 2 0.0132 0.0648 0.2016
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0235 0.2487
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0049 0.0153
Giardia lamblia Kinase, CMGC MAPK 0.0159 0.0796 0.2434
Echinococcus granulosus ras GTP exchange factor 0.0013 0.0003 0.0003
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0069 0.0212
Brugia malayi jmjC domain containing protein 0.0042 0.0164 0.051
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0127 0.0578
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Onchocerca volvulus 0.0016 0.0018 0.0055
Echinococcus multilocularis GPCR, family 2 0.0132 0.0648 0.0648
Echinococcus granulosus solute carrier family 22 0.0016 0.0018 0.0018
Schistosoma mansoni protein kinase 0.0036 0.0126 0.0126
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0033 0.0103
Trichomonas vaginalis ran, putative 0.0023 0.006 0.0186
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0049 0.0049
Plasmodium falciparum protein kinase 7 0.0317 0.1652 0.6577
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0887 0.2759
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.1575
Onchocerca volvulus Alhambra homolog 0.0029 0.009 0.028
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0049 0.0152
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0018 0.0056
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0127 0.0397
Echinococcus granulosus tar DNA binding protein 0.0076 0.0348 0.0348
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Echinococcus granulosus CAAX prenyl protease 2 0.0101 0.0482 0.0482
Brugia malayi major facilitator superfamily protein 0.0016 0.0018 0.0056
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0115 0.0115
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0127 0.0397
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0101 0.0482 0.5106
Echinococcus granulosus Smad4 0.0018 0.0033 0.0033
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0014 0.001 0.0031
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0152 0.0152
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0007 0.0021
Loa Loa (eye worm) RNA binding protein 0.0076 0.0348 0.1084
Brugia malayi Probable ClpP-like protease 0.0078 0.0355 0.1105
Mycobacterium leprae Probable polyketide synthase Pks1 0.006 0.0258 0.661
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.015 0.1588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0049 0.0153
Trypanosoma brucei protein kinase, putative 0.0159 0.0796 0.8431
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0128 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0397
Toxoplasma gondii histone lysine methyltransferase SET1 0.0247 0.1272 0.7699
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.015 0.015
Brugia malayi N-terminal motif family protein 0.0013 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0019 0.0038 0.0174
Entamoeba histolytica CAAX prenyl protease family 0.0101 0.0482 0.1499
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0159 0.0796 0.8431
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.009 0.0421 0.0421
Schistosoma mansoni pyruvate kinase 0.0036 0.0127 0.0127
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0121 0.128
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.0107 0.0107
Echinococcus granulosus smad 0.0018 0.0033 0.0033
Entamoeba histolytica protein kinase, putative 0.0036 0.0126 0.0391
Trypanosoma brucei glucose transporter, putative 0.0035 0.0121 0.128
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0461
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0149 0.0675
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.006 0.0131
Loa Loa (eye worm) sugar transporter 0.0016 0.0018 0.0056
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0018 0.0056
Schistosoma mansoni dep domain containing protein 0.0018 0.0032 0.0032
Trypanosoma brucei glucose transporter 1E 0.0035 0.0121 0.128
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.02 0.2115
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0014 0.001 0.0104
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.007 0.0319
Toxoplasma gondii hypothetical protein 0.0021 0.0046 0.028
Mycobacterium ulcerans sugar transporter 0.0016 0.0018 0.0056
Echinococcus multilocularis neuropeptide s receptor 0.1051 0.5641 0.5641
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0032 0.0107 0.0487
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0041 0.0153 0.0695
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0348 0.0348
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0095 0.1005
Loa Loa (eye worm) hypothetical protein 0.0032 0.0106 0.0329
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0027 0.0085
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0049 0.0049
Mycobacterium tuberculosis Probable thioesterase TesA 0.0047 0.0188 0.0855
Schistosoma mansoni dishevelled 0.0018 0.0032 0.0032
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0121 0.128
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0159 0.0796 0.4816
Toxoplasma gondii hypothetical protein 0.0021 0.0046 0.028
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.007 0.0278
Echinococcus granulosus solute carrier family 22 0.0016 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0012 0.000005437 0.000005437
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0049 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0461
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.1387 0.4316
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0448 0.0448
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0105 0.0504 0.0504
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0032 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0121 0.128
Trichomonas vaginalis helicase, putative 0.0029 0.0093 0.0288
Onchocerca volvulus 0.0016 0.0018 0.0055
Brugia malayi multidrug resistance protein 3 0.0012 0.0001 0.0002
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0149
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.016 0.016
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0048 0.0217
Entamoeba histolytica hypothetical protein 0.0026 0.0073 0.0226
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0145 0.0575
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0127 0.135
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0126 0.0393
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0033
Echinococcus granulosus microtubule associated protein 2 0.1425 0.7671 0.7671
Schistosoma mansoni lipoxygenase 0.0089 0.0417 0.0417
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0416 0.2192 0.6822
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.1387 0.4315
Onchocerca volvulus 0.0016 0.0018 0.0055
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0032 0.0099
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0053 0.0219 0.0996
Loa Loa (eye worm) hypothetical protein 0.0284 0.1477 0.4597
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0348 0.1084
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.02 0.02
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0008 0.0024
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.1387 0.4316
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0604 0.3213 1
Leishmania major protein kinase, putative 0.0036 0.0126 0.1337
Entamoeba histolytica CAAX amino terminal protease family 0.0021 0.0046 0.0142
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0078 0.2005
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0014 0.001 0.0104
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0003 0.0011
Chlamydia trachomatis pyruvate kinase 0.0036 0.0127 0.358
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0049 0.0152
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0145 0.1534
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0127 0.135
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0126 0.0393
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0012 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Plasmodium vivax hypothetical protein, conserved 0.004 0.0149 0.059
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0461
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0355 0.1105
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0033 0.0033
Toxoplasma gondii type I fatty acid synthase, putative 0.004 0.0151 0.0914
Schistosoma mansoni flap endonuclease-1 0.0027 0.0079 0.0079
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0604 0.3213 1
Schistosoma mansoni methyltransferase-related 0.0017 0.0025 0.0025
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0106 0.112
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Giardia lamblia Lysyl-tRNA synthetase 0.0025 0.0068 0.0157
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0012 0.0001 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0019 0.0057
Plasmodium falciparum phd finger protein, putative 0.0029 0.009 0.0358
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0126 0.0501
Onchocerca volvulus 0.013 0.064 0.199
Mycobacterium ulcerans fatty acid synthase Fas 0.0018 0.0029 0.0091
Giardia lamblia PHD finger protein 15 0.0029 0.009 0.0226
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0115 0.2935
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.006 0.006
Mycobacterium leprae conserved hypothetical protein 0.004 0.0149 0.3804
Chlamydia trachomatis lysine--tRNA ligase 0.0025 0.0068 0.1909
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0463
Echinococcus multilocularis CAAX prenyl protease 2 0.0101 0.0482 0.0482
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0049 0.0049
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0121 0.128
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0539 0.1676
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.006 0.0258 0.0804
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0014 0.001 0.001
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0049 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.013 0.064 0.1992
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0003 0.0009
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.009 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0126 0.0126
Loa Loa (eye worm) glutaminase 0.0268 0.139 0.4325
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0127 0.135
Plasmodium vivax sugar transporter, putative 0.0016 0.0018 0.007
Plasmodium falciparum protein kinase 6 0.0475 0.2512 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0049 0.0049
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0049 0.0049
Loa Loa (eye worm) Smad1 0.0018 0.0033 0.0103
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.006 0.0258 0.661
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.006 0.0637
Trypanosoma brucei sugar transporter, putative 0.0016 0.0018 0.0192
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0149 0.0149
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0049 0.0152
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0235 0.0933
Brugia malayi glutaminase DH11.1 0.0268 0.139 0.4325
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0046 0.0184 0.0833
Plasmodium vivax importin-beta 2, putative 0.0032 0.0106 0.0419
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0128 0.0626 0.0626
Trichomonas vaginalis hypothetical protein 0.0016 0.0019 0.0057
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0033 0.0033
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0127 0.0505
Plasmodium vivax hexose transporter 0.0112 0.0539 0.2143
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Echinococcus granulosus jumonji domain containing protein 0.004 0.0152 0.0152
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.1311 0.5956
Echinococcus granulosus solute carrier family 22 0.0016 0.0018 0.0018
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0068 0.0068
Brugia malayi MAP kinase sur-1 0.0159 0.0796 0.2477
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0093 0.0288
Brugia malayi RNA binding protein 0.0076 0.0348 0.1084
Onchocerca volvulus 0.0016 0.0018 0.0055
Echinococcus multilocularis cpg binding protein 0.0138 0.068 0.068
Brugia malayi Smad1 0.0018 0.0033 0.0103
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0126 0.0126
Echinococcus multilocularis solute carrier family 22 0.0016 0.0018 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0049 0.0049
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0132 0.0648 0.2016
Brugia malayi N-terminal motif family protein 0.037 0.194 0.604
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0938 0.2919
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0164 0.0164
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0127 0.0395
Toxoplasma gondii type I fatty acid synthase, putative 0.006 0.0258 0.1564
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0056
Echinococcus multilocularis geminin 0.0182 0.0921 0.0921
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.02 0.2115
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0149 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0018 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Entamoeba histolytica hypothetical protein 0.004 0.0149 0.0461
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0018 0.0055
Echinococcus multilocularis pyruvate kinase 0.0018 0.0033 0.0033
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0049 0.0153
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0032 0.0032
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0033 0.0033
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0127 0.135
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0093 0.0288
Echinococcus multilocularis pyruvate kinase 0.0036 0.0127 0.0127
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0149 0.0675
Brugia malayi RNA, U transporter 1 0.009 0.0424 0.1321
Brugia malayi hypothetical protein 0.0036 0.0128 0.0398
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0153
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.006 0.0258 0.1173
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0235 0.2487
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0014 0.001 0.0104
Giardia lamblia Hypothetical protein 0.0101 0.0482 0.1452
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.015 0.4057
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.009 0.0547
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0056 0.0239 0.6123
Toxoplasma gondii CAAX amino terminal protease family protein 0.0021 0.0046 0.028
Plasmodium falciparum pyruvate kinase 0.0036 0.0127 0.0505
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0069 0.0213
Schistosoma mansoni cytochrome P450 0.0012 0.000005437 0.000005437
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.02 0.02
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0093 0.0288
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0675
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0126 0.0501
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0012 0.0001 0.0003
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0018 0.0192
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.007 0.0278
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0126 0.1337
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0045 0.018 0.0559
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0049 0.0049
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0049 0.0192
Entamoeba histolytica hypothetical protein 0.0025 0.0068 0.0211
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0032 0.0032
Onchocerca volvulus 0.0021 0.0049 0.015
Schistosoma mansoni pyruvate kinase 0.0018 0.0033 0.0033
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0461 0.2435 0.7579
Schistosoma mansoni myst-related protein 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.009 0.0281
Onchocerca volvulus Fatty acid synthase homolog 0.0102 0.0485 0.1509
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.02 0.0907
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0095 0.1005
Onchocerca volvulus 0.0016 0.0018 0.0055
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0145 0.1534
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.006 0.0237
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0033
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0049 0.0153
Leishmania major pyruvate kinase 0.0036 0.0127 0.135
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0159 0.0796 0.8431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0448 0.0448

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5623 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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