Detailed information for compound 1220836

Basic information

Technical information
  • TDR Targets ID: 1220836
  • Name: 1-(4-fluorophenyl)-5-oxo-N-[2-(4-phenylpipera zin-1-yl)sulfonylethyl]pyrrolidine-3-carboxam ide
  • MW: 474.548 | Formula: C23H27FN4O4S
  • H donors: 1 H acceptors: 4 LogP: 1.25 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1CC(=O)N(C1)c1ccc(cc1)F)NCCS(=O)(=O)N1CCN(CC1)c1ccccc1
  • InChi: 1S/C23H27FN4O4S/c24-19-6-8-21(9-7-19)28-17-18(16-22(28)29)23(30)25-10-15-33(31,32)27-13-11-26(12-14-27)20-4-2-1-3-5-20/h1-9,18H,10-17H2,(H,25,30)
  • InChiKey: QAKCKHMJNACMND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-fluorophenyl)-5-oxo-N-[2-[(4-phenyl-1-piperazinyl)sulfonyl]ethyl]-3-pyrrolidinecarboxamide
  • 1-(4-fluorophenyl)-5-keto-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]pyrrolidine-3-carboxamide
  • G678-0668
  • NCGC00141626-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0048 0.0102 0.0617
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0181 0.0548 0.3502
Brugia malayi Variant SH3 domain containing protein 0.0131 0.0378 0.0378
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Trypanosoma brucei glucose transporter 2A 0.0035 0.0058 0.0149
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0102 0.0077
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Entamoeba histolytica phospholipase D, putative 0.3007 1 1
Brugia malayi hypothetical protein 0.0048 0.0102 0.0102
Schistosoma mansoni inositol monophosphatase 0.0044 0.0088 0.0082
Plasmodium vivax CDK-related protein kinase 6, putative 0.0476 0.1534 0.9886
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0015
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0051 0.006
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0048 0.0102 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Echinococcus multilocularis phospholipase d3 0.0567 0.1839 0.1832
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0395 0.0388
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0028 0.006
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0009 0.0002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0055 0.0144
Brugia malayi Bromodomain containing protein 0.006 0.0141 0.0141
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.016 0.0151
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0055 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Onchocerca volvulus 0.0048 0.0102 0.051
Schistosoma mansoni sorting nexin 0.0131 0.0378 0.0372
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0048 0.0102 0.051
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Leishmania major hypothetical protein, conserved 0.0036 0.0062 0.0204
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Plasmodium falciparum phosphoinositide-binding protein, putative 0.0131 0.0378 0.2404
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0055 0.014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0386 0.0379
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0073 0.0192
Trichomonas vaginalis centaurin gamma, putative 0.0048 0.0102 0.1049
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0009 0.001
Onchocerca volvulus 0.0131 0.0378 0.2019
Onchocerca volvulus Alhambra homolog 0.006 0.0141 0.0723
Brugia malayi jmjC domain containing protein 0.0036 0.0062 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0009 0.0009
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0141 0.0132
Echinococcus granulosus phd:f box containing protein 0.0036 0.0062 0.0054
Brugia malayi Cytohesin 3 0.0048 0.0102 0.0102
Entamoeba histolytica phospholipase D active site domain-containing protein 0.2525 0.839 0.8385
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0034 0.0057 0.0322
Echinococcus multilocularis sorting nexin 0.0131 0.0378 0.037
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0058 0.0517
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0102 0.0095
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0081 0.022
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0081 0.0679
Echinococcus granulosus phospholipase d3 0.0567 0.1839 0.1832
Trypanosoma brucei rac serine-threonine kinase, putative 0.005 0.0109 0.0298
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0055 0.0046
Echinococcus granulosus RUN 0.0021 0.0013 0.0004
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Giardia lamblia Liver stage antigen-like protein 0.0131 0.0378 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0049 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0135 0.0395 0.047
Schistosoma mansoni hypothetical protein 0.0048 0.0102 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Schistosoma mansoni rab6-interacting 0.0021 0.0013 0.0006
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0034 0.0057 0.0144
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.0631 0.0631
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0481 0.1552 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0259 0.0806 0.0798
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0058 0.0153
Schistosoma mansoni lipoxygenase 0.0089 0.0238 0.0232
Leishmania major protein kinase, putative 0.0034 0.0057 0.0172
Echinococcus multilocularis sorting nexin 2 0.0131 0.0378 0.037
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0071 0.0676
Leishmania major serine/threonine-protein kinase a, putative 0.005 0.0109 0.0463
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0131 0.0378 0.0378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0009 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0071 0.0558
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0427 0.0419
Echinococcus granulosus lamin 0.0033 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.2525 0.839 1
Trypanosoma brucei cardiolipin synthetase, putative 0.1049 0.3449 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0427 0.0419
Loa Loa (eye worm) Plekhf2 protein 0.0048 0.0102 0.0122
Brugia malayi Pre-SET motif family protein 0.0032 0.0049 0.0049
Loa Loa (eye worm) PX domain-containing protein 0.0131 0.0378 0.0451
Plasmodium falciparum mitogen-activated protein kinase 2 0.0181 0.0548 0.3502
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0049 0.004
Echinococcus granulosus calcium dependent secretion activator 1 0.0048 0.0102 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0317 0.3636
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.005 0.0109 0.0302
Trypanosoma brucei PX domain containing protein, putative 0.0131 0.0378 0.1079
Loa Loa (eye worm) hypothetical protein 0.0481 0.1552 0.185
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Toxoplasma gondii hypothetical protein 0.0131 0.0378 0.1079
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0034 0.0054 0.0045
Brugia malayi RNA binding protein 0.0133 0.0386 0.0386
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0071 0.0772
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0401 0.0395
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0481 0.1552 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.0378 0.0451
Entamoeba histolytica ARF GTPase activating protein, putative 0.0048 0.0102 0.0077
Echinococcus multilocularis GPCR, family 2 0.0065 0.016 0.0151
Loa Loa (eye worm) hypothetical protein 0.006 0.0141 0.0168
Echinococcus multilocularis RUN 0.0021 0.0013 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0044 0.0088 0.0241
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.0631 0.0752
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0048 0.0102 0.0093
Echinococcus multilocularis beta 1 syntrophin 0.0048 0.0102 0.0093
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0071 0.0558
Echinococcus granulosus tumor protein p63 0.0361 0.115 0.1142
Echinococcus granulosus phospholipase D1 0.3007 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0065
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0055 0.0066
Loa Loa (eye worm) syntrophin-1 0.0048 0.0102 0.0122
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Loa Loa (eye worm) beta-lactamase 0.0039 0.0071 0.0085
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.005 0.0109 0.0298
Schistosoma mansoni vav2 0.0048 0.0102 0.0095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Loa Loa (eye worm) TRAF4-associated factor 2 0.0131 0.0378 0.0451
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Trypanosoma cruzi cardiolipin synthetase, putative 0.1049 0.3449 1
Brugia malayi Sugar transporter family protein 0.0112 0.0317 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0057 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0009 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0401 0.0395
Trypanosoma cruzi cardiolipin synthetase, putative 0.1049 0.3449 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.016 0.0151
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0102 0.1049
Trypanosoma brucei cardiolipin synthetase 0.1049 0.3449 1
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0102 0.0122
Toxoplasma gondii hypothetical protein 0.0048 0.0102 0.0277
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0058 0.0153
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0062 0.0056
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0481 0.1552 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.016 0.019
Brugia malayi PHD-finger family protein 0.0019 0.0007 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0025 0.0017
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Giardia lamblia Prolyl-tRNA synthetase 0.0034 0.0054 0.0817
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0009 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0401 0.4584
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus multilocularis inositol monophosphatase 1 0.0044 0.0088 0.008
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Brugia malayi jmjC domain containing protein 0.0036 0.0062 0.0062
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.005 0.0109 0.0302
Echinococcus granulosus oxysterol binding protein 9 0.0048 0.0102 0.0093
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0062 0.0056
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0102 0.0281
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0074
Brugia malayi TBC domain containing protein 0.0048 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0048 0.0102 0.0095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0011 0.0004
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0048 0.0102 0.0102
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0028 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Echinococcus multilocularis nischarin 0.0131 0.0378 0.037
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0048 0.0102 0.0093
Loa Loa (eye worm) PX domain-containing protein 0.0131 0.0378 0.0451
Schistosoma mansoni dynamin 0.0048 0.0102 0.0095
Schistosoma mansoni myotubularin-related protein 0.0048 0.0102 0.0095
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0034 0.0054 0.6893
Echinococcus multilocularis musashi 0.0033 0.0051 0.0042
Schistosoma mansoni serine/threonine-protein kinase 0.005 0.0109 0.0103
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0025 0.0124
Echinococcus granulosus GRB2 associated binding protein 3 0.0048 0.0102 0.0093
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0025 0.0025
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0102 0.0281
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0102 0.0077
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0034 0.0057 0.0145
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0071 0.0191
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Plasmodium falciparum phd finger protein, putative 0.006 0.0141 0.0869
Plasmodium vivax hypothetical protein, conserved 0.006 0.0141 0.0869
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0102 0.0077
Brugia malayi jmjC domain containing protein 0.0036 0.0062 0.0062
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0055 0.0163
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0427 0.0427
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0427 0.0419
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0395 0.0388
Echinococcus granulosus tar DNA binding protein 0.0133 0.0386 0.0377
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0025 0.0019
Brugia malayi Inositol-1 0.0044 0.0088 0.0088
Echinococcus multilocularis sorting nexin 4 0.0131 0.0378 0.037
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0481 0.1552 0.4489
Onchocerca volvulus 0.0048 0.0102 0.051
Trypanosoma cruzi rac serine-threonine kinase, putative 0.005 0.0109 0.0302
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0102 0.0102
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0013 0.0037
Leishmania major cardiolipin synthetase, putative 0.0481 0.1552 0.8418
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0048 0.0102 0.051
Schistosoma mansoni thyroid hormone receptor 0.002 0.0009 0.0002
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0025 0.012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0081 0.0307
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0071 0.0416
Echinococcus granulosus pdz domain containing protein 0.0048 0.0102 0.0093
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0055 0.0144
Echinococcus granulosus pleckstrin y domain containing family A 0.0048 0.0102 0.0093
Echinococcus granulosus Oxysterol binding protein 11 0.0048 0.0102 0.0093
Brugia malayi hypothetical protein 0.0021 0.0013 0.0013
Schistosoma mansoni rab6-interacting 0.0021 0.0013 0.0006
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0054 0.0047
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0259 0.0806 0.0798
Entamoeba histolytica hypothetical protein 0.0048 0.0102 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0386 0.0379
Schistosoma mansoni hypothetical protein 0.0037 0.0064 0.0058
Echinococcus multilocularis phospholipase D1 0.3007 1 1
Schistosoma mansoni lamin 0.0033 0.0051 0.0044
Schistosoma mansoni lipoxygenase 0.0127 0.0366 0.0359
Loa Loa (eye worm) PH domain-containing protein 0.0048 0.0102 0.0122
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0102 0.1049
Brugia malayi MAX-1A 0.0048 0.0102 0.0102
Echinococcus multilocularis phospholipase D 0.2656 0.8826 0.8825
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0034 0.0057 0.0067
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0051 0.0051
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0025 0.0019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0071 0.0071
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0048 0.0102 0.0093
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0481 0.1552 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0062 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0048 0.0102 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0081 0.0795
Mycobacterium ulcerans glutaminase 0.027 0.0845 1
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Loa Loa (eye worm) TAR-binding protein 0.0133 0.0386 0.046
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.005 0.0109 0.0302
Toxoplasma gondii aldehyde dehydrogenase 0.0137 0.0401 0.1145
Echinococcus multilocularis rac serine:threonine kinase 0.005 0.0109 0.0101
Onchocerca volvulus 0.0048 0.0102 0.051
Brugia malayi glutaminase DH11.1 0.027 0.0845 0.0845
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus multilocularis GRB2 associated binding protein 3 0.0048 0.0102 0.0093
Mycobacterium tuberculosis Conserved protein 0.0039 0.0071 0.0772
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0048 0.0102 0.0093
Schistosoma mansoni sorting nexin 0.0131 0.0378 0.0372
Brugia malayi Phospholipase D. Active site motif family protein 0.0567 0.1839 0.1839
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0102 0.0122
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.0769 1
Echinococcus granulosus geminin 0.0679 0.2213 0.2206
Onchocerca volvulus 0.0053 0.0119 0.06
Echinococcus granulosus lysine specific demethylase 5A 0.0135 0.0395 0.0386
Schistosoma mansoni coup transcription factor 0.002 0.0009 0.0002
Plasmodium falciparum calcium-dependent protein kinase 7 0.005 0.0109 0.0663
Schistosoma mansoni polycystin 1-related 0.0021 0.0013 0.0006
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Trichomonas vaginalis inositol monophosphatase, putative 0.0044 0.0088 0.0882
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0049 0.004
Plasmodium falciparum oxysterol-binding protein, putative 0.0048 0.0102 0.0617
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0055 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0009 0.0009
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0048 0.0102 0.0095
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0062 0.0056
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Trichomonas vaginalis esterase, putative 0.0039 0.0071 0.0676
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0071 0.0064
Brugia malayi Phospholipase D. Active site motif family protein 0.1049 0.3449 0.3449
Trypanosoma brucei glucose transporter 1E 0.0035 0.0058 0.0149
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0048 0.0102 0.0093
Leishmania major phosphoinositide-binding protein, putative 0.0131 0.0378 0.1946
Leishmania major hypothetical protein, conserved 0.0048 0.0102 0.0423
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0025 0.012
Trypanosoma brucei PH domain containing protein, putative 0.0048 0.0102 0.0277
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0081 0.0072
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.005 0.0109 0.1135
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0119 0.0112
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.0631 0.0631
Entamoeba histolytica protein kinase, putative 0.0034 0.0057 0.0031
Entamoeba histolytica hypothetical protein 0.0037 0.0064 0.0039
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0006
Onchocerca volvulus Putative phospholipase D 0.0567 0.1839 1
Loa Loa (eye worm) sorting nexin 12 0.0131 0.0378 0.0451
Schistosoma mansoni ap endonuclease 0.0042 0.0081 0.0074
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0044 0.0088 0.0237
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0048 0.0102 0.0095
Echinococcus granulosus intermediate filament protein 0.0033 0.0051 0.0042
Trichomonas vaginalis alpha chimerin, putative 0.0048 0.0102 0.1049
Entamoeba histolytica hypothetical protein 0.0048 0.0102 0.0077
Echinococcus granulosus lamin dm0 0.0033 0.0051 0.0042
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0062 0.0162
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Toxoplasma gondii protein kinase, putative 0.0317 0.1002 0.289
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0058 0.0149
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Schistosoma mansoni hypothetical protein 0.0065 0.016 0.0153
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Chlamydia trachomatis phospholipase D superfamily protein 0.0481 0.1552 1
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0102 0.0281
Brugia malayi beta-lactamase 0.0039 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0048 0.0102 0.0077
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Echinococcus multilocularis cytohesin 1 0.0048 0.0102 0.0093
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0081 0.0795
Trypanosoma cruzi hexose transporter 0.0035 0.0058 0.0153
Echinococcus granulosus oxysterol binding protein 1 0.0048 0.0102 0.0093
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0127 0.0366 0.0358
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0062 0.0054
Entamoeba histolytica protein kinase, putative 0.0034 0.0057 0.0031
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.0057 0.0322
Echinococcus multilocularis Ras associated and pleckstrin y 0.0048 0.0102 0.0093
Onchocerca volvulus 0.0131 0.0378 0.2019
Echinococcus granulosus serine/threonine protein kinase 0.005 0.0109 0.0101
Trypanosoma cruzi Autophagy-related protein 24 0.0131 0.0378 0.1083
Loa Loa (eye worm) hypothetical protein 0.0131 0.0378 0.0451
Echinococcus granulosus Rho GTPase activating protein 24 0.0048 0.0102 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0009 0.0009
Echinococcus multilocularis pleckstrin y domain containing family A 0.0048 0.0102 0.0093
Echinococcus multilocularis myotubularin protein 13 0.0048 0.0102 0.0093
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0427 0.0419
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.005 0.0109 0.0302
Loa Loa (eye worm) hypothetical protein 0.1958 0.6492 0.7738
Echinococcus granulosus peregrin 0.006 0.0141 0.0132
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.006
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Leishmania major glucose transporter, lmgt1 0.0035 0.0058 0.018
Entamoeba histolytica hypothetical protein 0.0181 0.0546 0.0522
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0028 0.0065
Loa Loa (eye worm) hypothetical protein 0.0206 0.0631 0.0752
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0034 0.0054 0.0029
Brugia malayi Muscleblind-like protein 0.0177 0.0535 0.0535
Loa Loa (eye worm) phospholipase D 0.0567 0.1839 0.2192
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0062 0.0162
Echinococcus multilocularis muscleblind protein 0.0177 0.0535 0.0526
Wolbachia endosymbiont of Brugia malayi cardiolipin synthase 0.0481 0.1552 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0062 0.0054
Loa Loa (eye worm) RNA binding protein 0.0133 0.0386 0.046
Trypanosoma cruzi PX domain containing protein, putative 0.0131 0.0378 0.1083
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Brugia malayi TAR-binding protein 0.0133 0.0386 0.0386
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0013 0.0004
Schistosoma mansoni hypothetical protein 0.0065 0.016 0.0153
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0065
Schistosoma mansoni serine/threonine-protein kinase 0.005 0.0109 0.0103
Mycobacterium ulcerans lipase LipD 0.0039 0.0071 0.0558
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0427 0.0421
Echinococcus granulosus sorting nexin 0.0131 0.0378 0.037
Loa Loa (eye worm) cytohesin 3 0.0048 0.0102 0.0122
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0131 0.0378 0.1079
Brugia malayi Uncoordinated protein 104 0.0048 0.0102 0.0102
Brugia malayi jmjC domain containing protein 0.0036 0.0062 0.0062
Echinococcus granulosus sorting nexin 14 0.0131 0.0378 0.037
Brugia malayi TRAF4-associated factor 2 0.0131 0.0378 0.0378
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Brugia malayi PXA domain containing protein 0.0131 0.0378 0.0378
Brugia malayi hypothetical protein 0.0021 0.0013 0.0013
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0112 0.0317 0.0308
Mycobacterium ulcerans beta-lactamase 0.0039 0.0071 0.0558
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0048 0.0102 0.0095
Brugia malayi jmjC domain containing protein 0.0135 0.0395 0.0395
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.005 0.0109 0.0463
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0071 0.0772
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0386 0.0379
Plasmodium falciparum calcium-dependent protein kinase 1 0.0034 0.0057 0.0322
Leishmania major glucose transporter, lmgt3 0.0035 0.0058 0.018
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Brugia malayi hypothetical protein 0.0037 0.0064 0.0064
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0081 0.048
Giardia lamblia Hypothetical protein 0.0131 0.0378 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.0535 0.0637
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0058 0.0149
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0062 0.0054
Schistosoma mansoni zinc finger protein 0.0048 0.0102 0.0095
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0137 0.0401 0.2072
Schistosoma mansoni hypothetical protein 0.0065 0.016 0.0153
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0081 0.0081
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0062 0.0056
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Toxoplasma gondii facilitative glucose transporter GT1 0.0112 0.0317 0.0901
Onchocerca volvulus 0.0039 0.0071 0.0341
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0034 0.0057 0.0048
Onchocerca volvulus 0.0048 0.0102 0.051
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0048 0.0102 0.0617
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Echinococcus multilocularis muscleblind protein 1 0.0177 0.0535 0.0526
Loa Loa (eye worm) oxysterol binding protein 0.0048 0.0102 0.0122
Entamoeba histolytica phospholipase D, putative 0.3007 1 1
Schistosoma mansoni hypothetical protein 0.0065 0.016 0.0153
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0028 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Toxoplasma gondii AtPH1 family protein 0.0048 0.0102 0.0277
Brugia malayi AF-10 protein 0.0019 0.0007 0.0007
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0073 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0058 0.0517
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0071 0.0064
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.0049 0.0041
Schistosoma mansoni protein kinase 0.0034 0.0057 0.005
Schistosoma mansoni growth factor receptor-bound protein 0.0048 0.0102 0.0095
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0102 0.0281
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0062 0.0054
Onchocerca volvulus 0.0021 0.0013 0.0021
Schistosoma mansoni rho gtpase activating protein 0.0048 0.0102 0.0095
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0034 0.0054 0.0054
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0025 0.0017
Toxoplasma gondii ABC1 family protein 0.0039 0.0071 0.0187
Plasmodium vivax WD domain, G-beta repeat domain containing protein 0.0131 0.0378 0.2404
Toxoplasma gondii phospholipase D active site domain-containing protein 0.1049 0.3449 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Schistosoma mansoni hypothetical protein 0.0048 0.0102 0.0095
Giardia lamblia Hypothetical protein 0.0131 0.0378 1
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Brugia malayi jmjC domain containing protein 0.0259 0.0806 0.0806
Onchocerca volvulus 0.0033 0.0051 0.0228
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Trichomonas vaginalis glutaminase, putative 0.027 0.0845 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0055 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Toxoplasma gondii Oxysterol-binding protein 0.0048 0.0102 0.0277
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0055 0.0046
Trypanosoma cruzi NIMA-related kinase, putative 0.005 0.0109 0.0302
Echinococcus multilocularis dynamin 1 0.0048 0.0102 0.0093
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0071 0.0062
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0013 0.0037
Schistosoma mansoni syntrophin 0.0048 0.0102 0.0095
Toxoplasma gondii hypothetical protein 0.0048 0.0102 0.0277
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0048 0.0102 0.0093
Schistosoma mansoni sorting nexin 0.0131 0.0378 0.0372
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0009 0.0009
Trypanosoma brucei differentiation inhibitory kinase 0.0133 0.0386 0.11
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0033
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0102 0.0077
Echinococcus multilocularis sorting nexin 6 0.0131 0.0378 0.037
Leishmania major zinc finger protein kinase-like 0.0133 0.0386 0.1986
Schistosoma mansoni dynamin 0.0048 0.0102 0.0095
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0013 0.0015
Plasmodium falciparum protein kinase 6 0.0476 0.1534 0.9886
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0131 0.0378 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Echinococcus granulosus Pleckstrin y 0.0048 0.0102 0.0093
Trypanosoma brucei PX domain containing protein, putative 0.0131 0.0378 0.1079
Echinococcus granulosus beta 1 syntrophin 0.0048 0.0102 0.0093
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Plasmodium vivax JmjC domain containing protein 0.0036 0.0062 0.036
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0081 0.048
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0048 0.0102 0.0077
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0028 0.0134
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0137 0.0401 0.5134
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0048 0.0102 0.0617
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.016 0.016
Echinococcus multilocularis tar DNA binding protein 0.0133 0.0386 0.0377
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0058 0.0517
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0048 0.0102 0.0093
Echinococcus multilocularis Phox 0.0131 0.0378 0.037
Schistosoma mansoni glucose transport protein 0.0112 0.0317 0.031
Brugia malayi Sorting nexin 12 0.0131 0.0378 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0062 0.0054
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0071 0.0772
Brugia malayi Latrophilin receptor protein 2 0.0065 0.016 0.016
Trichomonas vaginalis kinesin light chain, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus granulosus cytohesin 1 0.0048 0.0102 0.0093
Plasmodium vivax PH domain containing protein 0.0048 0.0102 0.0617
Schistosoma mansoni protein kinase 0.0034 0.0057 0.005
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0055 0.0558
Loa Loa (eye worm) hypothetical protein 0.0053 0.0119 0.0141
Leishmania major hypothetical protein, conserved 0.0026 0.0028 0.0012
Brugia malayi hypothetical protein 0.0026 0.0028 0.0028
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0137 0.0401 0.0393
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0081 0.0097
Trypanosoma cruzi hypothetical protein 0.0131 0.0378 0.1083
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0081 0.5
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Onchocerca volvulus 0.0039 0.0071 0.0341
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0141 0.0132
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0055 0.0046
Plasmodium vivax cardiolipin synthetase, putative 0.0481 0.1552 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0034 0.0057 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.005 0.0109 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0427 0.0421
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0048 0.0102 0.0281
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0071 0.0191
Brugia malayi nuclear receptor NHR-88 0.002 0.0009 0.0009
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0102 0.1049
Echinococcus granulosus nischarin 0.0131 0.0378 0.037
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Onchocerca volvulus 0.0021 0.0013 0.0021
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Plasmodium vivax calcium-dependent protein kinase, putative 0.0034 0.0057 0.0322
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0028 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0058 0.0517
Leishmania major glucose transporter, lmgt2 0.0035 0.0058 0.018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0102 0.0617
Onchocerca volvulus 0.0048 0.0102 0.051
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0048 0.0102 0.0093
Plasmodium falciparum hexose transporter 0.0112 0.0317 0.2007
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0048 0.0102 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0013 0.0004
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0025 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0009 0.0009
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0062 0.0054
Plasmodium vivax hexose transporter 0.0112 0.0317 0.2007
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Brugia malayi Pre-SET motif family protein 0.0224 0.069 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus multilocularis geminin 0.0679 0.2213 0.2206
Schistosoma mansoni sortingnexin-related 0.0131 0.0378 0.0372
Brugia malayi Cam kinase protein 1 0.0034 0.0057 0.0057
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Entamoeba histolytica PX domain protein 0.0131 0.0378 0.0354
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0071 0.0772
Schistosoma mansoni hypothetical protein 0.0112 0.0317 0.031
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Schistosoma mansoni glucose transport protein 0.0112 0.0317 0.031
Echinococcus multilocularis sorting nexin 0.0131 0.0378 0.037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0044 0.0088 0.0241
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0424 0.0505
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0062 0.0054
Onchocerca volvulus 0.0039 0.0071 0.0341
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0055 0.0046
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0102 0.1049
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Loa Loa (eye worm) PX domain-containing protein 0.0131 0.0378 0.0451
Schistosoma mansoni hypothetical protein 0.0141 0.0413 0.0406
Brugia malayi Oxysterol-binding protein 0.0048 0.0102 0.0102
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0073 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0071 0.0676
Onchocerca volvulus Putative zinc finger protein 0.0048 0.0102 0.051
Schistosoma mansoni nuclear hormone receptor 0.002 0.0009 0.0002
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0048 0.0102 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0009 0.001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0009 0.0002
Brugia malayi beta-lactamase family protein 0.0039 0.0071 0.0071
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0049 0.0123
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.005 0.0109 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Echinococcus granulosus Phox 0.0131 0.0378 0.037
Echinococcus multilocularis actin binding protein anillin 0.0048 0.0102 0.0093
Schistosoma mansoni hypothetical protein 0.0679 0.2213 0.2208
Schistosoma mansoni hypothetical protein 0.0048 0.0102 0.0095
Loa Loa (eye worm) uncoordinated protein 104 0.0048 0.0102 0.0122
Schistosoma mansoni protein kinase 0.0034 0.0057 0.005
Onchocerca volvulus outspread protein homolog 0.0048 0.0102 0.051
Echinococcus granulosus Pleckstrin y 0.0048 0.0102 0.0093
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0055 0.0055
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Schistosoma mansoni jumonji domain containing protein 0.0218 0.0672 0.0666
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0009 0.001
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Giardia lamblia Hypothetical protein 0.0131 0.0378 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0044 0.0088 0.0882
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0071 0.0676
Onchocerca volvulus 0.0032 0.0049 0.022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0039 0.0071 0.0772
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0071 0.9712
Echinococcus granulosus phospholipase D 0.2656 0.8826 0.8825
Trypanosoma cruzi serine/threonine protein kinase, putative 0.005 0.0109 0.0302
Leishmania major protein kinase, putative 0.005 0.0109 0.0463
Brugia malayi Plekhf2 protein 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0049 0.0042
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0102 0.0102
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0427 0.0509
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Trichomonas vaginalis hypothetical protein 0.0048 0.0102 0.1049
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0102 0.0095
Giardia lamblia hypothetical protein 0.0131 0.0378 1
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.005 0.0109 0.0298
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0073 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0044 0.0088 0.0063
Schistosoma mansoni inositol monophosphatase 0.0044 0.0088 0.0082
Echinococcus multilocularis lysine specific demethylase 5A 0.0135 0.0395 0.0386
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0013 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0071 0.0187
Loa Loa (eye worm) inositol-1 0.0044 0.0088 0.0105
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0102 0.0077
Trypanosoma cruzi Autophagy-related protein 24 0.0131 0.0378 0.1083
Schistosoma mansoni glutaminase 0.027 0.0845 0.0839
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0071 0.0772
Onchocerca volvulus 0.0314 0.0991 0.5367
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0045 0.0036
Trichomonas vaginalis centaurin alpha, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0034 0.0054 0.0472
Leishmania major protein kinase, putative 0.005 0.0109 0.0463
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0044 0.0088 0.0767
Echinococcus granulosus sorting nexin 0.0131 0.0378 0.037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0401 0.4584
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0062 0.0074
Echinococcus granulosus ribosomal protein S6 kinase delta 1 0.0133 0.0386 0.0377
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0071 0.0062
Echinococcus multilocularis Rho GTPase activating protein 24 0.0048 0.0102 0.0093
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0048 0.0102 0.0095
Giardia lamblia Hypothetical protein 0.0131 0.0378 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0064 0.0056
Loa Loa (eye worm) glutaminase 2 0.027 0.0845 0.1007
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0034 0.0054 0.0045
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0071 0.0676
Brugia malayi Syntrophin-1 0.0048 0.0102 0.0102
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0048 0.0102 0.1049
Brugia malayi MH2 domain containing protein 0.0144 0.0424 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0102 0.0095
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0034 0.0057 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0048 0.0102 0.1049
Echinococcus multilocularis Pleckstrin y 0.0048 0.0102 0.0093
Brugia malayi probable spectrin beta chain 0.0048 0.0102 0.0102
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Plasmodium falciparum phosphoinositide-binding protein, putative 0.0131 0.0378 0.2404
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.005 0.0109 0.1135
Plasmodium falciparum calcium-dependent protein kinase 4 0.0034 0.0057 0.0322
Onchocerca volvulus 0.0048 0.0102 0.051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0049 0.0042
Echinococcus granulosus inositol monophosphatase 1 0.0044 0.0088 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0427 0.0421
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0141 0.0168
Brugia malayi ecdysteroid receptor 0.002 0.0009 0.0009
Echinococcus multilocularis tumor protein p63 0.0361 0.115 0.1142
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0481 0.1552 1
Brugia malayi PHD-finger family protein 0.006 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0405
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0062 0.0054
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0141 0.039
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0044 0.0088 0.0347
Brugia malayi Protein K4 0.0481 0.1552 0.1552
Echinococcus multilocularis sorting nexin 14 0.0131 0.0378 0.037
Schistosoma mansoni phospholipase D 0.3007 1 1
Loa Loa (eye worm) glutaminase 0.027 0.0845 0.1007
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0048 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0131 0.0378 0.0451
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0062 0.0074
Echinococcus granulosus DCC interacting protein 13 beta 0.0048 0.0102 0.0093
Leishmania major hypothetical protein, conserved 0.0048 0.0102 0.0423
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0058 0.0517
Onchocerca volvulus 0.0255 0.0794 0.429
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0034 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.1958 0.6492 0.7738
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus multilocularis Oxysterol binding protein 11 0.0048 0.0102 0.0093
Echinococcus granulosus Pleckstrin y 0.0048 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.003
Trypanosoma cruzi PX domain containing protein, putative 0.0131 0.0378 0.1083
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0424 0.0505
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0071 0.0772
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0055 0.014
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Entamoeba histolytica PH domain containing protein 0.0048 0.0102 0.0077
Echinococcus multilocularis Pleckstrin y 0.0048 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0034 0.0057 0.0145
Echinococcus granulosus myotubularin protein 13 0.0048 0.0102 0.0093
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0062 0.0162
Loa Loa (eye worm) hypothetical protein 0.2525 0.839 1
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Trypanosoma cruzi Protein kinase B 0.005 0.0109 0.0302
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0049 0.0042
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0048 0.0102 0.0095
Onchocerca volvulus 0.0048 0.0102 0.051
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0102 0.0617
Echinococcus multilocularis oxysterol binding protein 9 0.0048 0.0102 0.0093
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0055 0.0046
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.005 0.0109 0.0663
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.005 0.0109 0.0463
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0071 0.0676
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0127 0.0366 0.0358
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0009 0.001
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0009 0.0002
Schistosoma mansoni hypothetical protein 0.006 0.0141 0.0134
Brugia malayi PX domain containing protein 0.0131 0.0378 0.0378
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0081 0.0072
Plasmodium falciparum calcium-dependent protein kinase 5 0.0034 0.0057 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0009 0.0002
Schistosoma mansoni hypothetical protein 0.0679 0.2213 0.2208
Echinococcus granulosus dynamin 1 0.0048 0.0102 0.0093
Brugia malayi steroid hormone receptor 0.002 0.0009 0.0009
Echinococcus multilocularis jumonji domain containing protein 0.0083 0.0219 0.0211
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0013 0.0004
Mycobacterium leprae Probable lipase LipE 0.0039 0.0071 0.9712
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0102 0.1049
Leishmania major hypothetical protein, conserved 0.0131 0.0378 0.1946
Brugia malayi isocitrate dehydrogenase 0.0034 0.0055 0.0055
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0131 0.0378 0.0451
Echinococcus granulosus oxysterol binding protein 3 0.0048 0.0102 0.0093
Schistosoma mansoni intermediate filament proteins 0.0033 0.0051 0.0044
Toxoplasma gondii phosphatidylinositol transfer protein 0.0048 0.0102 0.0277
Onchocerca volvulus 0.0033 0.0051 0.0228
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0048 0.0102 0.0281
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0137 0.0401 0.0393
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0044 0.0088 0.0882
Trypanosoma cruzi hypothetical protein 0.0131 0.0378 0.1083
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0081 0.0056
Trichomonas vaginalis centaurin beta, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Echinococcus granulosus sorting nexin 4 0.0131 0.0378 0.037
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0062 0.0056
Entamoeba histolytica hypothetical protein 0.0131 0.0378 0.0354
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.016 0.0151
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.005 0.0109 0.0298
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0044 0.0088 0.0237
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0071 0.0772
Brugia malayi Oxysterol binding protein 0.0048 0.0102 0.0102
Trypanosoma brucei protein kinase, putative 0.005 0.0109 0.0298
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0034 0.0057 0.0322
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Brugia malayi hypothetical protein 0.0481 0.1552 0.1552
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0055 0.0312
Brugia malayi intermediate filament protein 0.0033 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0177 0.0535 0.0637
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0081 0.0216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0009 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0064 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Loa Loa (eye worm) hypothetical protein 0.0131 0.0378 0.0451
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Echinococcus granulosus jumonji domain containing protein 0.0083 0.0219 0.0211
Schistosoma mansoni thyroid hormone receptor 0.002 0.0009 0.0002
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0567 0.1839 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0058 0.0517
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0058 0.0149
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0064 0.0056
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0141 0.0134
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Echinococcus granulosus sorting nexin 6 0.0131 0.0378 0.037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0102 0.0102
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0048 0.0102 0.0122
Trichomonas vaginalis set domain proteins, putative 0.0255 0.0794 0.9382
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0025 0.21
Echinococcus multilocularis lamin 0.0033 0.0051 0.0042
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0055 0.014
Echinococcus granulosus sorting nexin 13 0.0131 0.0378 0.037
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0141 0.039
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0314 0.0991 0.1181
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0009 0.0002
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0481 0.1552 1
Loa Loa (eye worm) rho-GTPase-activating 0.0048 0.0102 0.0122
Leishmania major folate/biopterin transporter, putative 0.005 0.0109 0.0463
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0102 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0131 0.0378 0.2404
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0013 0.0004
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0048 0.0102 0.0122
Plasmodium vivax SET domain protein, putative 0.0032 0.0049 0.0273
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0073 0.0196
Entamoeba histolytica hypothetical protein 0.0048 0.0102 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Echinococcus granulosus GPCR family 2 0.0065 0.016 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0037 0.0064 0.0039
Brugia malayi PXA domain containing protein 0.0131 0.0378 0.0378
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.069 0.0823
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0073 0.0427
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0015
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0081 0.0903
Echinococcus multilocularis peregrin 0.006 0.0141 0.0132
Brugia malayi Doublecortin family protein 0.0021 0.0013 0.0013
Plasmodium falciparum calcium-dependent protein kinase 2 0.0034 0.0057 0.0322
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Schistosoma mansoni sorting nexin 0.0131 0.0378 0.0372
Plasmodium falciparum PH domain-containing protein, putative 0.0048 0.0102 0.0617
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0034 0.0057 0.0145
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0058 0.0517
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0081 0.1577
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0048 0.0102 0.0093
Giardia lamblia PHD finger protein 15 0.006 0.0141 0.3278
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0481 0.1552 1
Brugia malayi hypothetical protein 0.0314 0.0991 0.0991
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0386 0.0379
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0048 0.0102 0.0093
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0181 0.0548 0.1572
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0071 0.0085
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0073 0.0192
Trypanosoma cruzi hypothetical protein 0.0048 0.0102 0.0281
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0481 0.1552 0.1546
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0401 0.4584
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0386 0.0379
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0353 0.0421
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Trypanosoma cruzi zinc finger protein kinase, putative 0.0133 0.0386 0.1104
Echinococcus granulosus muscleblind protein 0.0177 0.0535 0.0526
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0102 0.0617
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.001
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.005 0.0109 0.0298
Schistosoma mansoni glucose transport protein 0.0112 0.0317 0.031
Entamoeba histolytica PH domain containing protein kinase, putative 0.005 0.0109 0.0084
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0054 0.0047
Entamoeba histolytica hypothetical protein 0.0037 0.0064 0.0039
Entamoeba histolytica PH domain containing protein 0.0048 0.0102 0.0077
Echinococcus multilocularis pdz domain containing protein 0.0048 0.0102 0.0093
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0102 0.1049
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Plasmodium falciparum protein kinase 7 0.0317 0.1002 0.644
Echinococcus granulosus General substrate transporter 0.0096 0.0264 0.0256
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.0049 0.0041
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0048 0.0102 0.0281
Trypanosoma brucei glucose transporter, putative 0.0035 0.0058 0.0149
Brugia malayi Dynamin 0.0048 0.0102 0.0102
Schistosoma mansoni lamin 0.0033 0.0051 0.0044
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Entamoeba histolytica p21-activated kinase 0.005 0.0109 0.0084
Entamoeba histolytica PH domain containing protein 0.0048 0.0102 0.0077
Brugia malayi nuclear hormone receptor 0.002 0.0009 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0009 0.0009
Brugia malayi Dynamin 0.0048 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0039 0.0071 0.0252
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0051 0.006
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.016 0.0151
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0009 0.0002
Echinococcus multilocularis calcium dependent secretion activator 1 0.0048 0.0102 0.0093
Echinococcus multilocularis General substrate transporter 0.0096 0.0264 0.0256
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Trypanosoma cruzi NIMA-related kinase, putative 0.005 0.0109 0.0302
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0048 0.0102 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0058 0.0153
Loa Loa (eye worm) AGC/AKT protein kinase 0.005 0.0109 0.013
Trypanosoma brucei Autophagy-related protein 24 0.0131 0.0378 0.1079
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Loa Loa (eye worm) sugar transporter 0.0112 0.0317 0.0378
Entamoeba histolytica hypothetical protein 0.0131 0.0378 0.0354
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0131 0.0378 0.0354
Echinococcus multilocularis DCC interacting protein 13 beta 0.0048 0.0102 0.0093
Mycobacterium tuberculosis Conserved protein 0.0039 0.0071 0.0772
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0102 0.0077
Echinococcus granulosus sorting nexin 2 0.0131 0.0378 0.037
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0062 0.0054
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0058 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Chlamydia trachomatis phospholipase D superfamily protein 0.0481 0.1552 1
Schistosoma mansoni loxhd1 0.0021 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0048 0.0102 0.0093
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.005 0.0109 0.0302
Brugia malayi PH domain containing protein 0.0048 0.0102 0.0102
Echinococcus multilocularis ribosomal protein S6 kinase delta 1 0.0133 0.0386 0.0377
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0102 0.0077
Loa Loa (eye worm) hypothetical protein 0.0065 0.016 0.019
Brugia malayi Pleckstrin Homology Domain 0.0048 0.0102 0.0102
Loa Loa (eye worm) PXA domain-containing protein 0.0131 0.0378 0.0451
Trypanosoma cruzi rac serine-threonine kinase, putative 0.005 0.0109 0.0302
Trypanosoma cruzi hypothetical protein 0.0131 0.0378 0.1083
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.0317 0.0308
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0009 0.0009
Echinococcus multilocularis 0.0131 0.0378 0.037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0009 0.0009
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0073 0.0427
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.005 0.0109 0.1135
Schistosoma mansoni zinc finger protein 0.0048 0.0102 0.0095
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0062 0.0166
Echinococcus multilocularis Pleckstrin y 0.0048 0.0102 0.0093
Onchocerca volvulus Protein melted homolog 0.0048 0.0102 0.051
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.005 0.0109 0.0298
Mycobacterium ulcerans hypothetical protein 0.0039 0.0071 0.0558
Schistosoma mansoni ap endonuclease 0.0042 0.0081 0.0074
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0084
Echinococcus multilocularis oxysterol binding protein 1 0.0048 0.0102 0.0093
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0057 0.0048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0081 0.022
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.0413 0.0413
Entamoeba histolytica hypothetical protein 0.0037 0.0064 0.0039
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0028 0.006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0013 0.0004
Echinococcus multilocularis oxysterol binding protein 3 0.0048 0.0102 0.0093
Toxoplasma gondii exonuclease III APE 0.0042 0.0081 0.0216
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0057 0.05
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.0386 0.046
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0073 0.0795
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0073 0.0196
Entamoeba histolytica hypothetical protein 0.0048 0.0102 0.0077
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0062 0.0166
Toxoplasma gondii protein kinase domain-containing protein 0.005 0.0109 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0102 0.1049
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.0492
Trypanosoma cruzi PX domain containing protein, putative 0.0131 0.0378 0.1083
Echinococcus multilocularis lamin dm0 0.0033 0.0051 0.0042
Plasmodium falciparum calcium-dependent protein kinase 3 0.0034 0.0057 0.0322
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0055 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0567 0.1839 0.2192
Brugia malayi beta-lactamase family protein 0.0039 0.0071 0.0071
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0044 0.0088 0.0049
Brugia malayi Cadps2 protein 0.0048 0.0102 0.0102
Entamoeba histolytica hypothetical protein 0.005 0.0109 0.0084
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0378 0.4376
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0131 0.0378 0.0372
Schistosoma mansoni centaurin alpha 0.0048 0.0102 0.0095

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1683 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 32.6427 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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