Detailed information for compound 1240614

Basic information

Technical information
  • TDR Targets ID: 1240614
  • Name: ethyl 1-[(1-acetyl-3,4-dihydro-2H-quinolin-6- yl)sulfonyl]piperidine-4-carboxylate
  • MW: 394.485 | Formula: C19H26N2O5S
  • H donors: 0 H acceptors: 4 LogP: 1.53 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1CCN(CC1)S(=O)(=O)c1ccc2c(c1)CCCN2C(=O)C
  • InChi: 1S/C19H26N2O5S/c1-3-26-19(23)15-8-11-20(12-9-15)27(24,25)17-6-7-18-16(13-17)5-4-10-21(18)14(2)22/h6-7,13,15H,3-5,8-12H2,1-2H3
  • InChiKey: YPAWXGCRKRCTOJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[(1-acetyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester
  • 1-[(1-acetyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]isonipecotic acid ethyl ester
  • ethyl 1-[(1-ethanoyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]piperidine-4-carboxylate
  • ethyl 1-[(1-acetyl-1,2,3,4-tetrahydroquinolin-6-yl)sulfonyl]piperidine-4-carboxylate
  • ZINC04035064
  • EU-0092990
  • MLS000045250
  • SMR000026842

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0159 0.0534 0.0709
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0042 0.0099 0.0099
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0064 0.0085
Brugia malayi RE15519p 0.0159 0.0534 0.1808
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0228 0.0772
Schistosoma mansoni amine GPCR 0.0159 0.0534 0.0709
Echinococcus multilocularis dna polymerase kappa 0.004 0.0092 0.0092
Plasmodium falciparum transporter, putative 0.0137 0.0454 1
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0114 0.0369 0.1251
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0099 0.0733
Loa Loa (eye worm) hypothetical protein 0.0192 0.0659 0.2232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0053 0.014 0.0474
Loa Loa (eye worm) hypothetical protein 0.0286 0.1007 0.3412
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0023 0.0029 0.0274
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0098
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0033 0.0728
Leishmania major DNA polymerase eta, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0023 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Leishmania major C-8 sterol isomerase-like protein 0.0376 0.1344 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0072 0.0209 0.1185
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0031 0.0041
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0015 0.0015
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0015 0.002
Schistosoma mansoni neuropeptide receptor 0.0159 0.0534 0.0709
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0092 0.0686
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0064 0.0085
Schistosoma mansoni hypothetical protein 0.0049 0.0124 0.0164
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.0019 0.0025
Brugia malayi hypothetical protein 0.0019 0.0015 0.0051
Onchocerca volvulus Putative neutral sphingomyelinase 0.0023 0.0029 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0159 0.0534 0.0534
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0836 0.1111
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Brugia malayi beta-lactamase 0.0076 0.0228 0.0772
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.014 0.3079
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0137 0.0454 0.1537
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0033 0.0044
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0114 0.0369 0.2746
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0159 0.0534 0.0709
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0159 0.0534 0.0534
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0064 0.0217
Brugia malayi hypothetical protein 0.0286 0.1007 0.3412
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0019 0.0025
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0092 0.0123
Loa Loa (eye worm) hypothetical protein 0.0062 0.0173 0.0586
Brugia malayi CHE-14 protein 0.005 0.0131 0.0443
Schistosoma mansoni hypothetical protein 0.0126 0.0413 0.0549
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0018 0.0008 0.0011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0033 0.0246
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0029 0.0213
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0099 0.2174
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Echinococcus granulosus neutral sphingomyelinase 0.0023 0.0029 0.0038
Brugia malayi Blistered cuticle protein 3 0.0081 0.0243 0.0824
Schistosoma mansoni slit 0.0018 0.0008 0.0011
Echinococcus granulosus tumor protein p63 0.0389 0.1392 0.1849
Echinococcus granulosus slit 2 protein 0.0018 0.0008 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Onchocerca volvulus 0.0018 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0015 0.002
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0056 0.0152 0.0202
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Schistosoma mansoni DNA polymerase eta 0.004 0.0092 0.0123
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0019 0.0019
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0023 0.0029 0.0213
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.0019 0.0064
Echinococcus granulosus tachykinin peptides receptor 99D 0.0159 0.0534 0.0709
Loa Loa (eye worm) melatonin receptor type 1A 0.0159 0.0534 0.1808
Schistosoma mansoni opsin-like receptor 0.0159 0.0534 0.0709
Echinococcus granulosus serotonin receptor 0.0159 0.0534 0.0709
Leishmania major hypothetical protein, conserved 0.0023 0.0029 0.0213
Echinococcus multilocularis somatostatin receptor 0.0159 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni sex comb on midleg homolog 0.0056 0.0152 0.0202
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Brugia malayi GCC2 and GCC3 family protein 0.0018 0.0008 0.0027
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0126 0.0413 0.0549
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Brugia malayi Dopamine receptor 0.0159 0.0534 0.1808
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0228 0.0228
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0064 0.0085
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0033 0.0113
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0209 0.0278
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Brugia malayi G protein-coupled receptor F59B2.13 0.0159 0.0534 0.1808
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Echinococcus granulosus neuropeptide s receptor 0.0159 0.0534 0.0709
Brugia malayi putative neuropeptide receptor 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1007 0.1007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0099 0.0335
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0029 0.063
Echinococcus granulosus neurogenic locus notch protein 4 0.0018 0.0008 0.0011
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0137 0.0454 0.1537
Schistosoma mansoni opsin-like receptor 0.0159 0.0534 0.0709
Plasmodium vivax exodeoxyribonuclease III, putative 0.0023 0.0029 0.063
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0064 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0023
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0056 0.0152 0.0516
Plasmodium falciparum glutathione reductase 0.007 0.0204 0.4494
Brugia malayi N-terminal motif family protein 0.0196 0.0674 0.2284
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0064 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Trichomonas vaginalis ap endonuclease, putative 0.0114 0.0369 0.1651
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0159 0.0534 0.0709
Giardia lamblia Inositol 5-phosphatase 4 0.0023 0.0029 0.0577
Schistosoma mansoni amine GPCR 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0023 0.0029 0.0098
Brugia malayi hypothetical protein 0.0017 0.0007 0.0023
Loa Loa (eye worm) latrophilin receptor protein 2 0.0126 0.0413 0.1401
Loa Loa (eye worm) beta-lactamase 0.0076 0.0228 0.0772
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0159 0.0534 0.0709
Onchocerca volvulus 0.002 0.0019 0.0064
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0228 0.129
Onchocerca volvulus 0.0159 0.0534 0.1808
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0092 0.2033
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.005 0.0131 0.0443
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0092 0.0686
Toxoplasma gondii calcium binding egf domain-containing protein 0.0046 0.0114 0.2504
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Echinococcus granulosus lamin dm0 0.0026 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0228 0.129
Loa Loa (eye worm) hypothetical protein 0.005 0.0131 0.0443
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0092 0.0308
Echinococcus granulosus peptide allatostatin:somatostatin 0.0159 0.0534 0.0709
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.007 0.0204 0.1155
Onchocerca volvulus Peroxidase homolog 0.0081 0.0243 0.0824
Plasmodium falciparum thioredoxin reductase 0.007 0.0204 0.4494
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0007 0.0009
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0228 0.129
Schistosoma mansoni sex comb on midleg homolog 0.0056 0.0152 0.0202
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0033 0.0021
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Echinococcus multilocularis neuropeptide Y receptor 0.0159 0.0534 0.0534
Loa Loa (eye worm) glutathione reductase 0.007 0.0204 0.0691
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1007 0.1338
Brugia malayi hypothetical protein 0.0081 0.0243 0.0824
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0159 0.0534 0.0534
Echinococcus multilocularis nAChR subunit 0.002 0.0019 0.0019
Mycobacterium tuberculosis Conserved protein 0.0076 0.0228 0.129
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0099 0.0335
Loa Loa (eye worm) ACC-1 protein 0.002 0.0019 0.0064
Onchocerca volvulus 0.0137 0.0454 0.1537
Echinococcus multilocularis lamin dm0 0.0026 0.0041 0.0041
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.0019 0.0064
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0023 0.0029 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0228 0.0965
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Schistosoma mansoni cell polarity protein 0.0018 0.0008 0.0011
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.0019 0.0019
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0022 0.0164
Schistosoma mansoni polycystin 1-related 0.0019 0.0015 0.002
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.002 0.0019 0.0025
Echinococcus granulosus peroxidasin 0.0081 0.0243 0.0323
Echinococcus granulosus somatostatin receptor 0.0159 0.0534 0.0709
Echinococcus granulosus expressed conserved protein 0.011 0.0354 0.047
Onchocerca volvulus 0.0137 0.0454 0.1537
Echinococcus multilocularis histone acetyltransferase MYST2 0.0064 0.0181 0.0181
Loa Loa (eye worm) blistered cuticle protein 3 0.0081 0.0243 0.0824
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0836 0.1111
Onchocerca volvulus 0.0026 0.0041 0.0138
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0033 0.0246
Loa Loa (eye worm) hypothetical protein 0.0273 0.096 0.3251
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0007 0.0023
Echinococcus multilocularis neurogenic locus notch protein 4 0.0018 0.0008 0.0008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0159 0.0534 0.0709
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Schistosoma mansoni myelin transcription factor 1 myt1 0.0064 0.0181 0.0241
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0836 0.0836
Leishmania major hypothetical protein, conserved 0.0076 0.0228 0.1694
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0029 0.063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0064 0.0217
Onchocerca volvulus 0.0159 0.0534 0.1808
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0064 0.0217
Brugia malayi putative neuropeptide receptor NPR1 0.0159 0.0534 0.1808
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0041 0.0138
Schistosoma mansoni alpha-1 adrenergic receptor 0.0159 0.0534 0.0709
Echinococcus granulosus dna polymerase kappa 0.004 0.0092 0.0123
Schistosoma mansoni cript-related 0.0023 0.0029 0.0038
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Leishmania major pantothenate kinase subunit, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) thioredoxin reductase 0.007 0.0204 0.0691
Loa Loa (eye worm) norepinephrine transporter 0.0807 0.2952 1
Onchocerca volvulus 0.0137 0.0454 0.1537
Mycobacterium ulcerans hypothetical protein 0.0076 0.0228 0.0946
Loa Loa (eye worm) G-protein coupled receptor 0.0159 0.0534 0.1808
Brugia malayi Thioredoxin reductase 0.007 0.0204 0.0691
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Treponema pallidum exodeoxyribonuclease (exoA) 0.0114 0.0369 0.1184
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0064 0.0217
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0126 0.0413 0.1401
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0064 0.0085
Loa Loa (eye worm) hypothetical protein 0.0399 0.143 0.4846
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0209 0.0278
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0807 0.2952 0.392
Brugia malayi AKH receptor 0.0159 0.0534 0.1808
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.014 0.1039
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Echinococcus granulosus histone acetyltransferase MYST2 0.0064 0.0181 0.0241
Leishmania major RNA-editing complex protein MP100, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0064 0.0217
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0099 0.0335
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0064 0.0217
Echinococcus granulosus sterol regulatory element binding protein 0.005 0.0131 0.0173
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0019 0.0025
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0228 0.0772
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.0019 0.0025
Echinococcus multilocularis neuropeptides capa receptor 0.0159 0.0534 0.0534
Schistosoma mansoni lamin 0.0026 0.0041 0.0054
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0375 0.0498
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0228 0.129
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0159 0.0534 0.0709
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0033 0.0044
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.0064 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Echinococcus multilocularis expressed conserved protein 0.011 0.0354 0.0354
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0137 0.0454 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0114 0.0369 0.0369
Plasmodium vivax amine transporter, putative 0.0137 0.0454 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0228 0.0965
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0011 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0098
Loa Loa (eye worm) hypothetical protein 0.0283 0.0997 0.3377
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0092 0.0288
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0008 0.0008
Onchocerca volvulus Huntingtin homolog 0.0121 0.0394 0.1335
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0159 0.0534 0.0709
Schistosoma mansoni lipoxygenase 0.0081 0.0245 0.0325
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0018 0.0009 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0228 0.0965
Schistosoma mansoni neuropeptide F-like receptor 0.0159 0.0534 0.0709
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0092 0.0686
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Mycobacterium tuberculosis Probable exported protein 0.0023 0.0029 0.0162
Loa Loa (eye worm) animal heme peroxidase 0.0081 0.0243 0.0824
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0376 0.1344 0.4552
Onchocerca volvulus 0.0018 0.0008 0.0027
Echinococcus multilocularis musashi 0.0026 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0117 0.0381 0.1289
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.0019 0.0019
Schistosoma mansoni coup transcription factor 0.0033 0.0064 0.0085
Brugia malayi Calcium binding EGF domain containing protein 0.0046 0.0114 0.0385
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0209 0.0856
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Onchocerca volvulus 0.002 0.0019 0.0064
Brugia malayi Cation transporter family protein 0.002 0.0019 0.0064
Schistosoma mansoni neuropeptide receptor 0.0159 0.0534 0.0709
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0376 0.1344 0.4552
Echinococcus multilocularis GPCR, family 2 0.0126 0.0413 0.0413
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0159 0.0534 0.1808
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0159 0.0534 0.1808
Entamoeba histolytica recQ family DNA helicase 0.0021 0.0022 0.0093
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0022 0.0164
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Onchocerca volvulus 0.0018 0.0008 0.0027
Brugia malayi Niemann-Pick C1 protein precursor 0.0117 0.0381 0.1289
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0126 0.0413 0.0413
Onchocerca volvulus 0.0159 0.0534 0.1808
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Onchocerca volvulus 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Loa Loa (eye worm) mbt repeat family protein 0.0056 0.0152 0.0516
Brugia malayi Dopamine receptor protein 2 0.0159 0.0534 0.1808
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0114 0.0369 0.2091
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0029 0.0098
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0159 0.0534 0.0709
Echinococcus granulosus biogenic amine 5HT receptor 0.0283 0.0997 0.1324
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.001 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0064 0.0217
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0029 0.0098
Onchocerca volvulus Putative nachr subunit 0.002 0.0019 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Loa Loa (eye worm) serotonin transporter b 0.0807 0.2952 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0119 0.0387 0.0514
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0099 0.2174
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0064 0.0217
Echinococcus granulosus Protein patched homolog 1 0.005 0.0131 0.0173
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0029 0.0029
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Plasmodium vivax glutathione reductase, putative 0.007 0.0204 0.4494
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0209 0.0856
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0064 0.0217
Schistosoma mansoni hypothetical protein 0.0159 0.0534 0.0709
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) G-protein coupled receptor 0.0159 0.0534 0.1808
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0029 0.063
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0244 0.0854 0.0854
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0092 0.0123
Loa Loa (eye worm) solute carrier family 6 member 4 0.0807 0.2952 1
Onchocerca volvulus 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni sodium-dependent amino acid transporter 0.0137 0.0454 0.0602
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0385
Brugia malayi Serotonin receptor 0.0159 0.0534 0.1808
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.0019 0.0025
Schistosoma mansoni ap endonuclease 0.0114 0.0369 0.049
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Echinococcus granulosus sodium and chloride dependent glycine 0.0137 0.0454 0.0602
Echinococcus multilocularis g protein coupled receptor 0.0159 0.0534 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0064 0.0217
Schistosoma mansoni hypothetical protein 0.0159 0.0534 0.0709
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0099 0.0099
Onchocerca volvulus Peroxidase homolog 0.0081 0.0243 0.0824
Echinococcus granulosus GPCR family 2 0.0126 0.0413 0.0549
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Onchocerca volvulus Neuropeptide F receptor homolog 0.0159 0.0534 0.1808
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0019 0.0025
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0064 0.0085
Brugia malayi larval opioid receptor 0.0159 0.0534 0.1808
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0015 0.0325
Echinococcus multilocularis polycomb protein SCMH1 0.0056 0.0152 0.0152
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0155 0.0206
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0137 0.0454 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.0019 0.0025
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0029 0.063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0099 0.0339
Schistosoma mansoni biogenic amine receptor 0.0159 0.0534 0.0709
Brugia malayi nuclear hormone receptor 0.0033 0.0064 0.0217
Echinococcus granulosus SAM and MBT domain containing protein 0.0056 0.0152 0.0202
Loa Loa (eye worm) notch protein 0.0018 0.0008 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Mycobacterium leprae Probable lipase LipE 0.0076 0.0228 1
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Echinococcus multilocularis nAChR subunit 0.002 0.0019 0.0019
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0064 0.0085
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0114 0.0369 0.1633
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0058 0.016 0.0212
Echinococcus granulosus thioredoxin glutathione reductase 0.007 0.0204 0.0271
Brugia malayi notch-like transmembrane receptor 0.0018 0.0008 0.0027
Schistosoma mansoni lamin 0.0026 0.0041 0.0054
Treponema pallidum NADH oxidase 0.0024 0.0033 0.0037
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Echinococcus granulosus lamin 0.0026 0.0041 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Schistosoma mansoni amine GPCR 0.0159 0.0534 0.0709
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0033 0.0246
Echinococcus multilocularis notch 0.0018 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0228 0.1694
Schistosoma mansoni lipoxygenase 0.0116 0.0375 0.0498
Echinococcus multilocularis serotonin receptor 0.0283 0.0997 0.0997
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0008 0.0027
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0159 0.0534 0.0709
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0159 0.0534 0.0709
Mycobacterium tuberculosis Conserved protein 0.0076 0.0228 0.129
Echinococcus multilocularis neuropeptide receptor 0.0159 0.0534 0.0534
Schistosoma mansoni biogenic amine (5HT) receptor 0.0283 0.0997 0.1324
Onchocerca volvulus Dual oxidase homolog 0.0081 0.0243 0.0824
Brugia malayi Cytochrome P450 family protein 0.0033 0.0067 0.0228
Onchocerca volvulus 0.0159 0.0534 0.1808
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0019 0.0419
Schistosoma mansoni cpg binding protein 0.0063 0.0176 0.0234
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis lamin 0.0026 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Schistosoma mansoni rab6-interacting 0.0019 0.0015 0.002
Schistosoma mansoni hypothetical protein 0.0529 0.1916 0.2544
Onchocerca volvulus Putative cubilin 0.0018 0.0008 0.0027
Brugia malayi mbt repeat family protein 0.0056 0.0152 0.0516
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Schistosoma mansoni hypothetical protein 0.0049 0.0124 0.0164
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0163 0.0553
Echinococcus multilocularis SAM and MBT domain containing protein 0.0056 0.0152 0.0152
Loa Loa (eye worm) pax transcription factor protein 2 0.0233 0.0812 0.275
Brugia malayi follicle stimulating hormone receptor 0.0159 0.0534 0.1808
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Echinococcus multilocularis neutral sphingomyelinase 0.0023 0.0029 0.0029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0836 0.2833
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0023 0.0029 0.063
Trichomonas vaginalis esterase, putative 0.0076 0.0228 0.0965
Echinococcus granulosus alpha 1A adrenergic receptor 0.0159 0.0534 0.0709
Echinococcus multilocularis protein jagged 2 0.0018 0.0008 0.0008
Onchocerca volvulus Peroxidasin homolog 0.0081 0.0243 0.0824
Echinococcus granulosus G protein coupled receptor 139 0.0159 0.0534 0.0709
Echinococcus granulosus neuropeptides capa receptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0092 0.0313
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0018 0.0008 0.0027
Entamoeba histolytica recQ family helicase, putative 0.0042 0.0099 0.2209
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0836 0.1111
Loa Loa (eye worm) neuropeptide F receptor 0.0159 0.0534 0.1808
Echinococcus multilocularis fibrillin 1 0.0046 0.0114 0.0114
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0064 0.0085
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0033 0.0728
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0092 0.0686
Onchocerca volvulus Neurogenic locus notch homolog 0.0018 0.0008 0.0027
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0019 0.0019
Echinococcus multilocularis allatostatin A receptor 0.0159 0.0534 0.0534
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0064 0.0217
Echinococcus multilocularis sodium and chloride dependent glycine 0.0137 0.0454 0.0454
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0159 0.0534 0.1808
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0228 0.1694
Echinococcus granulosus protein jagged 1 0.0018 0.0008 0.0011
Brugia malayi beta-lactamase family protein 0.0076 0.0228 0.0772
Onchocerca volvulus 0.0019 0.0015 0.0051
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0008 0.0011
Schistosoma mansoni synaptojanin 0.0023 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Brugia malayi Cadherin domain containing protein 0.0018 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis microtubule associated protein 2 0.2035 0.753 0.753
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0064 0.0064
Brugia malayi hypothetical protein 0.0017 0.0007 0.0023
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0019 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0159 0.0534 0.0709
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0064 0.0217
Loa Loa (eye worm) animal heme peroxidase 0.0081 0.0243 0.0824
Echinococcus granulosus Niemann Pick C1 protein 0.0168 0.0568 0.0755
Brugia malayi hypothetical protein 0.0019 0.0015 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0159 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Echinococcus granulosus tm gpcr rhodopsin 0.0159 0.0534 0.0709
Echinococcus granulosus neuropeptide FF receptor 2 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Echinococcus multilocularis geminin 0.0529 0.1916 0.1916
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0019 0.0015 0.0051
Echinococcus granulosus g protein coupled receptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Brugia malayi exodeoxyribonuclease III family protein 0.0114 0.0369 0.1251
Echinococcus multilocularis neuropeptide s receptor 0.0159 0.0534 0.0534
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Onchocerca volvulus 0.0059 0.0163 0.0553
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Echinococcus multilocularis RUN 0.0019 0.0015 0.0015
Leishmania major DNA polymerase kappa, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0064 0.0064
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0033 0.0187
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0019 0.0025
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0099 0.0733
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Onchocerca volvulus 0.002 0.0019 0.0064
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0114 0.0369 0.2746
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Echinococcus multilocularis Tolloid protein 1 0.0046 0.0114 0.0114
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0092 0.0686
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0159 0.0534 0.1808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Echinococcus multilocularis synaptojanin 1 0.0023 0.0029 0.0029
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.014 0.3079
Brugia malayi Cation transporter family protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Onchocerca volvulus 0.0057 0.0155 0.0525
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0029 0.0213
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0019 0.0025
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0137 0.0454 0.0602
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0228 0.129
Brugia malayi G protein-coupled receptor 0.0159 0.0534 0.1808
Leishmania major hypothetical protein, conserved 0.0023 0.0029 0.0213
Mycobacterium ulcerans beta-lactamase 0.0076 0.0228 0.0946
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0159 0.0534 0.0534
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0029 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0023 0.0029 0.0213
Schistosoma mansoni sodium/chloride dependent transporter 0.0137 0.0454 0.0602
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.0274
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0019 0.001
Loa Loa (eye worm) RecQ helicase 0.0042 0.0099 0.0335
Onchocerca volvulus Slit protein homolog 0.0018 0.0008 0.0027
Echinococcus multilocularis orexin receptor type 2 0.0159 0.0534 0.0534
Echinococcus granulosus neuropeptide receptor 0.0159 0.0534 0.0709
Onchocerca volvulus 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0056 0.0152 0.0516
Schistosoma mansoni hypothetical protein 0.0273 0.096 0.1274
Brugia malayi Delta serrate ligand family protein 0.0018 0.0008 0.0027
Echinococcus multilocularis G protein coupled receptor 139 0.0159 0.0534 0.0534
Schistosoma mansoni laminin gamma-3 chain 0.0018 0.0008 0.0011
Brugia malayi hypothetical protein 0.0137 0.0454 0.1537
Schistosoma mansoni biogenic amine receptor 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0081 0.0243 0.0824
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0064 0.0064
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0159 0.0534 0.1808
Onchocerca volvulus 0.0058 0.016 0.0542
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0015 0.0015
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0023 0.0029 0.0098
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0064 0.0064
Trichomonas vaginalis glutaminase, putative 0.0576 0.2091 1
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0023 0.0029 0.0213
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0033 0.0021
Mycobacterium ulcerans glutaminase 0.0576 0.2091 1
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus granulosus synaptojanin 1 0.0023 0.0029 0.0038
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.0019 0.0064
Toxoplasma gondii hypothetical protein 0.0137 0.0454 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Echinococcus multilocularis neuropeptide FF receptor 2 0.0159 0.0534 0.0534
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0807 0.2952 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0019 0.0064
Onchocerca volvulus 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0137 0.0454 0.0602
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.0064 0.0085
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus granulosus serotonin transporter 0.0807 0.2952 0.392
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Schistosoma mansoni hypothetical protein 0.0126 0.0413 0.0549
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0021 0.0022 0.0486
Schistosoma mansoni DNA helicase recq5 0.0042 0.0099 0.0131
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.0019 0.0064
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0023 0.0029 0.0274
Echinococcus granulosus geminin 0.0529 0.1916 0.2544
Brugia malayi ORL1-like opioid receptor 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0076
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0399 0.143 0.4846
Trypanosoma brucei unspecified product 0.004 0.0092 0.0686
Schistosoma mansoni synaptojanin 0.0023 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0385
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0033 0.0033
Echinococcus granulosus allatostatin A receptor 0.0159 0.0534 0.0709
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0008 0.0027
Schistosoma mansoni hypothetical protein 0.0843 0.3085 0.4096
Trichomonas vaginalis ap endonuclease, putative 0.0114 0.0369 0.1651
Loa Loa (eye worm) animal heme peroxidase 0.0081 0.0243 0.0824
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0159 0.0534 0.0534
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0029 0.0213
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0033 0.0246
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0023
Echinococcus multilocularis neural cadherin 0.0018 0.0008 0.0008
Giardia lamblia DINP protein human, muc B family 0.004 0.0092 0.2337
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) hypothetical protein 0.0076 0.0228 0.0772
Echinococcus granulosus g-protein coupled receptor 0.0159 0.0534 0.0709
Echinococcus multilocularis cpg binding protein 0.0063 0.0176 0.0176
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0064 0.0085
Onchocerca volvulus 0.0159 0.0534 0.1808
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0092 0.0522
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0283 0.0997 0.3377
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.0313
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus g protein coupled receptor 0.0159 0.0534 0.0709
Echinococcus granulosus fibropellin Ia 0.0018 0.0008 0.0011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0064 0.0085
Schistosoma mansoni neuropeptide f receptor 76f 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0385
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0046 0.0114 0.0151
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0019 0.0025
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Onchocerca volvulus 0.002 0.0019 0.0064
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0159 0.0534 0.1808
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.0019 0.0064
Loa Loa (eye worm) animal heme peroxidase 0.0081 0.0243 0.0824
Schistosoma mansoni DNA helicase recq1 0.0042 0.0099 0.0131
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0029 0.0213
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Brugia malayi Melatonin receptor type 1A 0.0159 0.0534 0.1808
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.014 0.1039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis neuropeptide receptor 0.0159 0.0534 0.0534
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0137 0.0454 0.1537
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Onchocerca volvulus 0.0076 0.0228 0.0772
Brugia malayi latrophilin 2 splice variant baaae 0.0273 0.096 0.3251
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0019 0.0019
Echinococcus granulosus orexin receptor type 2 0.0159 0.0534 0.0709
Echinococcus granulosus polycomb protein SCMH1 0.0056 0.0152 0.0202
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0159 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Onchocerca volvulus 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus neuropeptide Y receptor 0.0159 0.0534 0.0709
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0228 0.129
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0159 0.0534 0.1808
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0092 0.0313
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0023 0.0029 0.0213
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Onchocerca volvulus 0.0159 0.0534 0.1808
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0114 0.0369 0.8139
Echinococcus multilocularis serotonin transporter 0.0807 0.2952 0.2952
Leishmania major trypanothione reductase 0.007 0.0204 0.1516
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0098
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0072 0.0209 0.1556
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0137 0.0454 0.0602
Echinococcus multilocularis sterol regulatory element binding protein 0.005 0.0131 0.0131
Schistosoma mansoni neuropeptide receptor 0.0159 0.0534 0.0709
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0064 0.0181 0.0614
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0228 0.1694
Brugia malayi Pax transcription factor protein 2 0.0233 0.0812 0.275
Trypanosoma brucei unspecified product 0.0028 0.0046 0.034
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Echinococcus granulosus 7tm_1 domain containing protein 0.0159 0.0534 0.0709
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0137 0.0454 0.0454
Loa Loa (eye worm) MBCTL1 0.0064 0.0181 0.0614
Brugia malayi Dopamine receptor protein 1 0.056 0.2029 0.6872
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0117 0.0381 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0228 0.0965
Echinococcus multilocularis deoxyribonuclease 1 2 0.0023 0.0029 0.0029
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0137 0.0454 0.1537
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0033 0.0246
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0092 0.0313
Schistosoma mansoni cpg binding protein 0.0063 0.0176 0.0234
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Loa Loa (eye worm) hypothetical protein 0.0807 0.2952 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0092 0.0288
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0021 0.0019 0.0419
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Echinococcus granulosus fmrfamide receptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Brugia malayi ecdysteroid receptor 0.0033 0.0064 0.0217
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0064 0.0085
Plasmodium falciparum amino acid transporter, putative 0.0137 0.0454 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0196 0.0674 0.2284
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0092 0.0686
Brugia malayi Animal haem peroxidase family protein 0.0081 0.0243 0.0824
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0015 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0064 0.0085
Echinococcus multilocularis protein jagged 1 0.0018 0.0008 0.0008
Schistosoma mansoni ap endonuclease 0.0114 0.0369 0.049
Echinococcus multilocularis sex peptide receptor 0.0159 0.0534 0.0534
Echinococcus granulosus sodium and chloride dependent glycine 0.0137 0.0454 0.0602
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Brugia malayi neuropeptide F receptor 0.0159 0.0534 0.1808
Brugia malayi hypothetical protein 0.0121 0.0394 0.1335
Onchocerca volvulus 0.002 0.0019 0.0064
Echinococcus granulosus Niemann Pick C1 protein 0.0117 0.0381 0.0505
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0126 0.0413 0.0413
Toxoplasma gondii thioredoxin reductase 0.007 0.0204 0.4494
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0137 0.0454 0.1537
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0836 0.0836
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0361 0.7952
Schistosoma mansoni neuropeptide receptor 0.0159 0.0534 0.0709
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Echinococcus granulosus protein jagged 2 0.0018 0.0008 0.0011
Brugia malayi Serotonin receptor 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Brugia malayi glutathione reductase 0.007 0.0204 0.0691
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0064 0.0085
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Echinococcus multilocularis Niemann Pick C1 protein 0.0168 0.0568 0.0568
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0072 0.0209 0.0278
Echinococcus granulosus delta-like protein 1 0.0018 0.0008 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Treponema pallidum hypothetical protein 0.0023 0.0029 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0056 0.0152 0.0516
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0018 0.0009 0.0031
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0008 0.0008
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0126 0.0413 0.1401
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0137 0.0454 0.0454
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0137 0.0454 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus granulosus nAChR subunit 0.002 0.0019 0.0025
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0228 0.0946
Echinococcus multilocularis g protein coupled receptor 0.0159 0.0534 0.0534
Brugia malayi Animal haem peroxidase family protein 0.0081 0.0243 0.0824
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0019 0.0064
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0137 0.0454 0.0602
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0335
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0033 0.0728
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0067 0.0228
Plasmodium falciparum thioredoxin reductase 0.0024 0.0033 0.0728
Leishmania major endonuclease/exonuclease protein-like protein 0.0023 0.0029 0.0213
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Onchocerca volvulus Huntingtin homolog 0.0121 0.0394 0.1335
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Brugia malayi neuropeptide F receptor 0.0159 0.0534 0.1808
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0064 0.0217
Trypanosoma brucei C-8 sterol isomerase, putative 0.0376 0.1344 1
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.014 0.3079
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0023 0.0029 0.063
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0159 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.0019 0.0025
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0007 0.0023
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0033 0.0728
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.014 0.1039
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0051
Brugia malayi Peroxidasin 0.0081 0.0243 0.0824
Echinococcus granulosus notch 0.0018 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Brugia malayi isocitrate dehydrogenase 0.0015 0 0.0001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0019 0.0064
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0126 0.0413 0.0549
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0155 0.0525
Onchocerca volvulus Chorion peroxidase homolog 0.0081 0.0243 0.0824
Onchocerca volvulus 0.0076 0.0228 0.0772
Echinococcus multilocularis laminin 0.0046 0.0114 0.0114
Brugia malayi EGF-like domain containing protein 0.0018 0.0008 0.0027
Loa Loa (eye worm) LGC-31 protein 0.002 0.0019 0.0064
Brugia malayi Animal haem peroxidase family protein 0.0081 0.0243 0.0824
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0033 0.0728
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0064 0.0217
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0092 0.0308
Echinococcus multilocularis g protein coupled receptor 0.0159 0.0534 0.0534
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0092 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Echinococcus multilocularis neuropeptides capa receptor 0.0159 0.0534 0.0534
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0137 0.0454 0.0602
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0023 0.0029 0.0029
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0228 0.129
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0159 0.0534 0.0709
Echinococcus granulosus nAChR subunit 0.002 0.0019 0.0025
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.0019 0.0064
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0159 0.0534 0.0709
Schistosoma mansoni patched 1 0.005 0.0131 0.0173
Echinococcus granulosus cpg binding protein 0.0063 0.0176 0.0234
Schistosoma mansoni amine GPCR 0.0159 0.0534 0.0709
Echinococcus granulosus traf and tnf receptor associated protein 0.0023 0.0029 0.0038
Brugia malayi GnHR receptor homolog 0.0159 0.0534 0.1808
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.0019 0.0025
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni histamine h1 receptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0807 0.2952 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0489 0.1764 1
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0126 0.0413 0.0549
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0114 0.0369 0.049
Schistosoma mansoni septate junction protein 0.0018 0.0008 0.0011
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0046 0.0114 0.0385
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0137 0.0454 0.1537
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0029 0.0098
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0023
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0023 0.0029 0.0213
Giardia lamblia hypothetical protein 0.0023 0.0029 0.0577
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0064 0.0064
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0019 0.0025
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Schistosoma mansoni sodium/chloride dependent transporter 0.0137 0.0454 0.0602
Brugia malayi nuclear receptor NHR-88 0.0033 0.0064 0.0217
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0137 0.0454 1
Onchocerca volvulus Arrow homolog 0.0046 0.0114 0.0385
Echinococcus granulosus dnaJ subfamily B 0.0843 0.3085 0.4096
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0033 0.0187
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0159 0.0534 0.0709
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0033 0.0246
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0114 0.0369 0.9686
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0159 0.0534 0.0534
Schistosoma mansoni rab6-interacting 0.0019 0.0015 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0092 0.0686
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis traf and tnf receptor associated protein 0.0023 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Onchocerca volvulus 0.0233 0.0812 0.275
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0046 0.034
Schistosoma mansoni microtubule-associated protein tau 0.2035 0.753 1
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.0019 0.0025
Echinococcus granulosus neuropeptide receptor 0.0159 0.0534 0.0709
Echinococcus granulosus protein jagged 1 0.0018 0.0008 0.0011
Brugia malayi G-protein coupled receptor 0.0159 0.0534 0.1808
Schistosoma mansoni sodium/chloride dependent transporter 0.0807 0.2952 0.392
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0064 0.0217
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Echinococcus multilocularis Niemann Pick C1 protein 0.0117 0.0381 0.0381
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.0064 0.0064
Schistosoma mansoni opsin-like receptor 0.0159 0.0534 0.0709
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0114 0.0369 0.8139
Leishmania major hypothetical protein, conserved 0.0023 0.0029 0.0213
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.0019 0.0064
Echinococcus multilocularis dnaJ subfamily B 0.0843 0.3085 0.3085
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0092 0.0123
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni peroxidasin 0.0081 0.0243 0.0323
Echinococcus multilocularis slit 2 protein 0.0018 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0028 0.0046 0.034
Brugia malayi Animal haem peroxidase family protein 0.0081 0.0243 0.0824
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Echinococcus multilocularis serotonin receptor 0.0283 0.0997 0.0997
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0042 0.0099 0.0099
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0019 0.0064
Brugia malayi sulfakinin receptor protein 0.0159 0.0534 0.1808
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0228 1
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0064 0.0085
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0033 0.0246
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.056 0.2029 0.6872
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0159 0.0534 0.0534
Echinococcus multilocularis fmrfamide receptor 0.0159 0.0534 0.0534
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0064 0.0217
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0114 0.0369 0.2746
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Brugia malayi Calcitonin receptor-like protein seb-1 0.0399 0.143 0.4846
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0029 0.0213
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0137 0.0454 0.1537
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0046 0.034
Schistosoma mansoni carbon catabolite repressor protein 0.0023 0.0029 0.0038
Onchocerca volvulus 0.002 0.0019 0.0064
Schistosoma mansoni hypothetical protein 0.0159 0.0534 0.0709
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0064 0.0181 0.0241
Schistosoma mansoni myosin xvIII 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0385
Echinococcus granulosus neurogenic locus protein delta 0.0018 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Onchocerca volvulus 0.0018 0.0008 0.0027
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.0019 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0411 0.0545
Brugia malayi Muscle positioning protein 4 0.0018 0.0008 0.0027
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0228 0.502
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0041 0.0138
Brugia malayi CCR4 0.0023 0.0029 0.0098
Onchocerca volvulus 0.0159 0.0534 0.1808
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0029 0.0038
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0019 0.0019
Onchocerca volvulus 0.0159 0.0534 0.1808
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0024 0.0033 0.0187
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0064 0.0181 0.0614
Echinococcus granulosus RUN 0.0019 0.0015 0.002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0836 0.2833
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0019 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Trypanosoma brucei trypanothione reductase 0.007 0.0204 0.1516
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni hypothetical protein 0.0049 0.0124 0.0164
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0015 0.0325
Echinococcus multilocularis fmrfamide receptor 0.0159 0.0534 0.0534
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) GABA receptor subunit 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Brugia malayi intermediate filament protein 0.0026 0.0041 0.0138
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0046 0.034
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0064 0.0085
Echinococcus granulosus microtubule associated protein 2 0.2035 0.753 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0114 0.0369 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0159 0.0534 0.0709
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0114 0.0369 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0159 0.0534 0.1808
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0228 0.0965
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Brugia malayi nuclear receptor RXR 0.0017 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0385
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Onchocerca volvulus 0.0023 0.0029 0.0098
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0046 0.0114 0.0385
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.0019 0.0064
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Brugia malayi Tachykinin-like peptides receptor 99D 0.0159 0.0534 0.1808
Plasmodium vivax hypothetical protein, conserved 0.0137 0.0454 1
Leishmania major hypothetical protein, conserved 0.0053 0.014 0.1039
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0046 0.0114 0.0385
Plasmodium vivax thioredoxin reductase, putative 0.007 0.0204 0.4494
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0029 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0064 0.0217
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0019 0.0019
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0064 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Schistosoma mansoni adenoreceptor 0.0159 0.0534 0.0709
Loa Loa (eye worm) neuropeptide F receptor 0.0159 0.0534 0.1808
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0042 0.0099 0.2174
Echinococcus multilocularis protein dispatched 1 0.0058 0.0157 0.0157
Loa Loa (eye worm) glutaminase 0.0576 0.2091 0.7082
Schistosoma mansoni neutral sphingomyelinase 0.0023 0.0029 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0019 0.0064
Brugia malayi hypothetical protein 0.0053 0.014 0.0474
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0375 0.0375
Mycobacterium ulcerans lipase LipD 0.0076 0.0228 0.0946
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.0019 0.0064
Schistosoma mansoni hypothetical protein 0.0529 0.1916 0.2544
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0064 0.0085
Schistosoma mansoni neuropeptide F-like receptor 0.0159 0.0534 0.0709
Brugia malayi Fibulin-1 precursor 0.0046 0.0114 0.0385
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0064 0.0217
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0024 0.0033 0.0187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0836 0.1111
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0228 0.0303
Echinococcus multilocularis neuropeptide receptor A26 0.0159 0.0534 0.0534
Brugia malayi steroid hormone receptor 0.0033 0.0064 0.0217
Brugia malayi hypothetical protein 0.0034 0.007 0.0237
Echinococcus granulosus neural cadherin 0.0018 0.0008 0.0011
Treponema pallidum sodium- and chloride- dependent transporter 0.0807 0.2952 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0228 0.0946
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0023 0.0029 0.0213
Plasmodium falciparum DNase I-like protein, putative 0.0023 0.0029 0.063
Schistosoma mansoni nocturnin 0.0023 0.0029 0.0038
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0041 0.0138
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Echinococcus multilocularis G-protein coupled receptor, putative 0.0159 0.0534 0.0534
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0064 0.0085
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0159 0.0534 0.1808
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0023 0.0029 0.0213
Toxoplasma gondii calcium binding egf domain-containing protein 0.0046 0.0114 0.2504
Echinococcus multilocularis dro:myosuppressin receptor 0.0159 0.0534 0.0534
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0011
Toxoplasma gondii hypothetical protein 0.0137 0.0454 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0033 0.0728
Loa Loa (eye worm) TYRA-2 protein 0.0159 0.0534 0.1808
Schistosoma mansoni cpg binding protein 0.0059 0.0163 0.0217
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0064 0.0085
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0029 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0159 0.0534 0.0534
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0042 0.0099 0.0335
Loa Loa (eye worm) glutaminase 2 0.0576 0.2091 0.7082
Schistosoma mansoni intermediate filament proteins 0.0026 0.0041 0.0054
Loa Loa (eye worm) ACC-1 protein 0.002 0.0019 0.0064
Onchocerca volvulus Peroxidasin homolog 0.0081 0.0243 0.0824
Brugia malayi mbt repeat family protein 0.0056 0.0152 0.0516
Brugia malayi G-protein coupled receptor 0.0159 0.0534 0.1808
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0023 0.0029 0.0274
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0159 0.0534 0.1808
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0029 0.0274
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Echinococcus multilocularis fat cadherin tumor suppressor 0.0018 0.0008 0.0008
Brugia malayi glutaminase DH11.1 0.0576 0.2091 0.7082
Schistosoma mansoni survival motor neuron protein 0.0058 0.016 0.0212
Echinococcus multilocularis protein patched 0.005 0.0131 0.0131
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0064 0.0064
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0019 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0064 0.0217
Plasmodium falciparum glutathione reductase 0.0024 0.0033 0.0728
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0022 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0064 0.0217
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0131 0.0494
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.002
Giardia lamblia Sgs1 DNA helicase, putative 0.0042 0.0099 0.2514
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0033 0.0246
Onchocerca volvulus 0.0076 0.0228 0.0772
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0008 0.0008
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.0019 0.0064
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0137 0.0454 0.0454
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0244 0.0854 0.1134
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0399 0.143 0.4846
Loa Loa (eye worm) hypothetical protein 0.0807 0.2952 1
Echinococcus granulosus neuropeptide Y receptor 0.0159 0.0534 0.0709
Schistosoma mansoni hypothetical protein 0.0365 0.1302 0.1729
Onchocerca volvulus 0.0026 0.0041 0.0138
Loa Loa (eye worm) hypothetical protein 0.0196 0.0674 0.2284
Echinococcus granulosus neuropeptide receptor A26 0.0159 0.0534 0.0709
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0132
Echinococcus granulosus sex peptide receptor 0.0159 0.0534 0.0709
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0019 0.0064
Echinococcus granulosus protein jagged 2 0.0018 0.0008 0.0011
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0018 0.0008 0.0027
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0029 0.0213
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Trypanosoma brucei RNA editing exonuclease 2 0.0023 0.0029 0.0213
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0159 0.0534 0.0534
Brugia malayi Doublecortin family protein 0.0019 0.0015 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0022 0.0486
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0023 0.0029 0.0213
Schistosoma mansoni biogenic amine receptor 0.0159 0.0534 0.0709
Mycobacterium tuberculosis Conserved protein 0.0076 0.0228 0.129
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0099 0.0339
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0064 0.0217
Echinococcus multilocularis dna polymerase eta 0.004 0.0092 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0033 0.0246
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0159 0.0534 0.0709
Brugia malayi Animal haem peroxidase family protein 0.0081 0.0243 0.0824
Echinococcus granulosus rhodopsin orphan GPCR 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0081 0.0243 0.0824
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Toxoplasma gondii exonuclease III APE 0.0114 0.0369 0.8139
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0033 0.0246
Echinococcus multilocularis sodium and chloride dependent glycine 0.0137 0.0454 0.0454
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0159 0.0534 0.0534
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0099 0.2174
Echinococcus multilocularis peroxidasin 0.0081 0.0243 0.0243
Toxoplasma gondii ABC1 family protein 0.0076 0.0228 0.502
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0114 0.0369 0.2746
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0159 0.0534 0.0709
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0159 0.0534 0.0709
Echinococcus multilocularis protein jagged 1 0.0018 0.0008 0.0008
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0042 0.0099 0.0131
Trypanosoma cruzi trypanothione reductase, putative 0.007 0.0204 0.1516
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.0019 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.014 0.3079
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0209 0.0856
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0064 0.0085
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0836 0.1111
Echinococcus multilocularis fibropellin Ia 0.0018 0.0008 0.0008
Schistosoma mansoni loxhd1 0.0019 0.0015 0.002
Onchocerca volvulus 0.0159 0.0534 0.1808
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus multilocularis thioredoxin glutathione reductase 0.007 0.0204 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Toxoplasma gondii EGF family domain-containing protein 0.0018 0.0008 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0092 0.0686
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0046 0.0114 0.0385
Schistosoma mansoni egf-like domain protein 0.0046 0.0114 0.0151
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0007 0.0023
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0099 0.0339
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0029 0.063
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0072 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0029 0.063
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0007 0.0009
Echinococcus multilocularis g-protein coupled receptor 0.0159 0.0534 0.0534
Schistosoma mansoni glutaminase 0.0576 0.2091 0.2776
Loa Loa (eye worm) hypothetical protein 0.0081 0.0243 0.0824
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0031 0.0031
Echinococcus multilocularis tumor protein p63 0.0389 0.1392 0.1392
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0033 0.07
Echinococcus granulosus biogenic amine 5HT receptor 0.0159 0.0534 0.0709
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Echinococcus granulosus neuropeptides capa receptor 0.0159 0.0534 0.0709
Schistosoma mansoni notch 0.0018 0.0008 0.0011
Loa Loa (eye worm) Notch2 0.0018 0.0008 0.0027
Brugia malayi hypothetical protein 0.0159 0.0534 0.1808
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0137 0.0454 0.0602
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.0019 0.0025
Echinococcus granulosus dna polymerase eta 0.004 0.0092 0.0123
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0376 0.1344 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0121 0.0394 0.1335
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0019 0.0019
Echinococcus granulosus intermediate filament protein 0.0026 0.0041 0.0054
Schistosoma mansoni nAChR subunit 0.002 0.0019 0.0025
Schistosoma mansoni amine GPCR 0.0159 0.0534 0.0709
Echinococcus granulosus g protein coupled receptor 0.0159 0.0534 0.0709
Echinococcus granulosus Tolloid protein 1 0.0046 0.0114 0.0151
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0027
Brugia malayi Cation transporter family protein 0.002 0.0019 0.0064
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Onchocerca volvulus 0.0159 0.0534 0.1808
Brugia malayi Cadherin domain containing protein 0.0018 0.0008 0.0027
Schistosoma mansoni growth hormone secretagogue receptor 0.0159 0.0534 0.0709
Echinococcus granulosus hypothetical protein 0.0159 0.0534 0.0709
Schistosoma mansoni biogenic amine (5HT) receptor 0.0159 0.0534 0.0709
Onchocerca volvulus 0.0807 0.2952 1
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0008 0.0011
Echinococcus granulosus bloom syndrome protein 0.0042 0.0099 0.0131
Onchocerca volvulus 0.0081 0.0243 0.0824
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Onchocerca volvulus 0.0018 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0126 0.0413 0.1401
Schistosoma mansoni hypothetical protein 0.0049 0.0124 0.0164
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0159 0.0534 0.0709
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0228 0.0303
Echinococcus granulosus dro:myosuppressin receptor 0.0159 0.0534 0.0709
Echinococcus granulosus laminin 0.0046 0.0114 0.0151
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0099 0.0733
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0159 0.0534 0.0709
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0159 0.0534 0.0534
Schistosoma mansoni hypothetical protein 0.0126 0.0413 0.0549
Schistosoma mansoni peroxidasin 0.0081 0.0243 0.0323
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.0159 0.0534 0.1808
Toxoplasma gondii aldehyde dehydrogenase 0.0072 0.0209 0.4612
Brugia malayi beta-lactamase family protein 0.0076 0.0228 0.0772
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0092 0.0522
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0064 0.0217
Echinococcus multilocularis neuropeptide Y receptor 0.0159 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0121 0.0394 0.1335
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0042 0.0099 0.0131
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.016 0.0542
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0076
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0029 0.0098
Brugia malayi CXXC zinc finger family protein 0.0059 0.0163 0.0553
Brugia malayi Isocitrate dehydrogenase 0.0015 0 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0228 0.0303
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0159 0.0534 0.0534

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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