Detailed information for compound 1343281

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 289.436 | Formula: C17H23NOS
  • H donors: 2 H acceptors: 1 LogP: 4.33 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][S+](C12CC3CC(C2)CC(C1)C3)NCc1ccccc1
  • InChi: 1S/C17H23NOS/c19-20(18-12-13-4-2-1-3-5-13)17-9-14-6-15(10-17)8-16(7-14)11-17/h1-5,14-16,18H,6-12H2
  • InChiKey: VMNLISQDQZBLRN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Entamoeba histolytica protein kinase, putative 0.0144 0.0107 0.0238
Echinococcus granulosus calcium activated potassium channel 0.0304 0.0837 0.0812
Brugia malayi protein kinase C3,putative 0.0356 0.1073 0.1161
Brugia malayi Protein kinase domain containing protein 0.1023 0.4112 0.4471
Echinococcus granulosus activin receptor type 0.0182 0.0278 0.0252
Schistosoma mansoni tyrosine kinase 0.02 0.0361 0.0612
Brugia malayi SRC-1 0.0532 0.1875 0.2035
Echinococcus granulosus casein kinase i 0.0245 0.0566 0.054
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0153 0.0149 0.0162
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0183 0.0285 0.0258
Echinococcus multilocularis SH2 motif 0.013 0.0044 0.0045
Echinococcus multilocularis 0.0274 0.07 0.0843
Echinococcus multilocularis protein kinase c epsilon type 0.0446 0.148 0.1793
Brugia malayi Protein kinase domain containing protein 0.0647 0.2395 0.2601
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0458 0.1538 0.1668
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0201 0.0367 0.1521
Echinococcus multilocularis c src tyrosine kinase 0.0332 0.0965 0.1166
Loa Loa (eye worm) hypothetical protein 0.0126 0.0027 0.0029
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0225 0.0477 0.4033
Schistosoma mansoni protein kinase C mu 0.0492 0.1693 0.2914
Onchocerca volvulus 0.0171 0.0229 0.0359
Echinococcus granulosus casein kinase I gamma 0.0417 0.1351 0.1327
Echinococcus multilocularis tyrosine protein kinase Abl 0.0513 0.1786 0.2165
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0027 0.0121
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.013 0.0044 0.0017
Echinococcus multilocularis calcium dependent protein kinase 0.0154 0.0153 0.0178
Schistosoma mansoni hypothetical protein 0.013 0.0044 0.0064
Plasmodium falciparum calcium-dependent protein kinase 4 0.0227 0.0485 0.2743
Leishmania major protein kinase, putative 0.0182 0.0278 0.1136
Echinococcus multilocularis epidermal growth factor receptor 0.092 0.364 0.4423
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0611 0.1044
Loa Loa (eye worm) TK/ABL protein kinase 0.071 0.2686 0.2923
Entamoeba histolytica protein kinase, putative 0.0164 0.02 0.0513
Loa Loa (eye worm) STAT protein 0.013 0.0044 0.0048
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0532 0.1875 0.2274
Giardia lamblia Kinase, CMGC GSK 0.029 0.0773 0.2435
Onchocerca volvulus 0.0158 0.0169 0.0243
Giardia lamblia Kinase, CMGC CLK 0.0347 0.1031 0.3769
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0126 0.0027 0.0024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0278 0.1217
Trypanosoma brucei protein kinase, putative 0.0182 0.0278 0.1126
Schistosoma mansoni tyrosine-protein kinase zap-70 0.013 0.0044 0.0064
Brugia malayi STAT protein, DNA binding domain containing protein 0.013 0.0044 0.004
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0188 0.0308 0.1258
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0327 0.094 0.1136
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0532 0.1875 0.2274
Schistosoma mansoni growth factor receptor-bound protein 0.0228 0.049 0.0834
Schistosoma mansoni serine/threonine protein kinase 0.0532 0.1873 0.3225
Brugia malayi Protein kinase domain containing protein 0.0371 0.1139 0.1233
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Entamoeba histolytica protein kinase, putative 0.0193 0.0331 0.0906
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0203 0.0375 0.1036
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0201 0.0367 0.1612
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.013 0.0044 0.0017
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0535 0.1887 0.2289
Giardia lamblia Kinase, CK1 Casein kinase 0.0245 0.0566 0.1365
Echinococcus multilocularis raf serine:threonine protein kinase 0.0204 0.038 0.0454
Giardia lamblia Kinase, STE STE20 0.0193 0.0331 0.0155
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0799 0.309 0.3363
Leishmania major protein kinase A catalytic subunit isoform 2 0.0255 0.0611 0.264
Echinococcus granulosus rho-associated protein kinase 1 0.0737 0.2806 0.2786
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Loa Loa (eye worm) AUR protein kinase 0.0328 0.0947 0.1031
Echinococcus granulosus suppressor of cytokine signaling 6 0.013 0.0044 0.0017
Loa Loa (eye worm) hypothetical protein 0.028 0.0728 0.0793
Schistosoma mansoni protein kinase 0.06 0.2183 0.3759
Onchocerca volvulus 0.0315 0.0887 0.1636
Echinococcus multilocularis SH2 domain containing adapter protein F 0.013 0.0044 0.0045
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.029 0.0773 0.1324
Trichomonas vaginalis AGC family protein kinase 0.0328 0.0947 0.4194
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.019 0.0317 0.0864
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0314 0.088 0.3855
Echinococcus multilocularis mitogen activated protein kinase 0.0188 0.0308 0.0366
Schistosoma mansoni SH2A 0.013 0.0044 0.0064
Loa Loa (eye worm) AGC/PKA protein kinase 0.0255 0.0611 0.0665
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0757 0.2898 0.3154
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0894 0.3521 0.3503
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0348 0.1034 0.101
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0527 0.1851 0.1829
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0027 0.0121
Loa Loa (eye worm) hypothetical protein 0.0275 0.0705 0.0767
Plasmodium falciparum casein kinase 2, alpha subunit 0.0225 0.0477 0.2642
Schistosoma mansoni vav2 0.0246 0.0569 0.0971
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0751 0.2871 0.3124
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0122 0.0007 0.0008
Schistosoma mansoni tyrosine kinase 0.0811 0.3144 0.542
Echinococcus granulosus nervana 2 0.0248 0.0582 0.0557
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0347 0.1031 0.4501
Echinococcus granulosus mitogen activated protein kinase 14 0.0359 0.1088 0.1064
Brugia malayi Protein kinase domain containing protein 0.0454 0.1519 0.1647
Brugia malayi Protein kinase domain containing protein 0.0239 0.054 0.058
Brugia malayi Protein kinase domain containing protein 0.0276 0.0706 0.0762
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Leishmania major casein kinase II, putative 0.0225 0.0477 0.2036
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0735
Brugia malayi Protein kinase domain 0.0193 0.0331 0.0354
Echinococcus granulosus mitogen activated protein kinase 0.0188 0.0308 0.0282
Brugia malayi STE20-like kinase MST 0.0582 0.2099 0.2279
Entamoeba histolytica protein kinase, putative 0.0276 0.0706 0.2023
Schistosoma mansoni protein kinase 0.0831 0.3237 0.5581
Brugia malayi hypothetical protein 0.0503 0.1741 0.1888
Echinococcus granulosus defective proboscis extension response 0.019 0.0314 0.0288
Echinococcus multilocularis insulin receptor 0.1023 0.4112 0.4998
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.1139 0.1957
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0159 0.0174 0.0204
Echinococcus multilocularis dual specificity 0.0276 0.0706 0.0851
Loa Loa (eye worm) TK/EGFR protein kinase 0.1393 0.5794 0.6306
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0314 0.088 0.0957
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0321 0.0914 0.1104
Schistosoma mansoni serine/threonine protein kinase 0.0737 0.2806 0.4837
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0929 0.3679 0.4471
Loa Loa (eye worm) hypothetical protein 0.0663 0.247 0.2688
Schistosoma mansoni tyrosine kinase 0.085 0.3321 0.5727
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0539 0.1905 0.2073
Brugia malayi Tyrosine-protein kinase abl-1 0.0513 0.1786 0.1937
Loa Loa (eye worm) hypothetical protein 0.0473 0.1605 0.1747
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0446 0.148 0.1611
Echinococcus granulosus tyrosine protein kinase Srms 0.1166 0.4759 0.4744
Echinococcus granulosus survival motor neuron protein 1 0.0275 0.0705 0.068
Schistosoma mansoni protein kinase 0.0225 0.0477 0.0813
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0285 0.126
Echinococcus granulosus Protein kinase C brain isozyme 0.0536 0.189 0.1868
Loa Loa (eye worm) hypothetical protein 0.0254 0.0607 0.0661
Brugia malayi hypothetical protein 0.0128 0.0035 0.0031
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0175 0.029
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Trichomonas vaginalis AGC family protein kinase 0.0392 0.1237 0.5479
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Echinococcus multilocularis cyclin dependent kinase 0.0268 0.0671 0.0808
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0894 0.3521 0.4278
Brugia malayi cell division control protein 2 homolog 0.0268 0.0671 0.0723
Brugia malayi casein kinase 1, delta 0.0245 0.0566 0.0609
Echinococcus multilocularis mitogen activated protein kinase 11 0.0359 0.1088 0.1316
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0525 0.1843 0.2006
Brugia malayi phosphoinositide-dependent protein kinase I 0.0183 0.0285 0.0302
Echinococcus granulosus tyrosine protein kinase Src42A 0.0532 0.1875 0.1853
Echinococcus granulosus dual specificity 0.0314 0.088 0.0855
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0757 0.2898 0.3148
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0268 0.0671 0.073
Echinococcus multilocularis nervana 2 0.0248 0.0582 0.07
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0559 0.1999 0.2425
Brugia malayi Variant SH3 domain containing protein 0.0153 0.0149 0.0155
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0259 0.0632 0.0607
Echinococcus multilocularis cyclin dependent kinase 1 0.0268 0.0671 0.0808
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0346 0.1026 0.1117
Loa Loa (eye worm) CAMK protein kinase 0.0158 0.0169 0.0184
Plasmodium falciparum serine/threonine protein kinase 0.0187 0.0301 0.0304
Schistosoma mansoni suppressor of cytokine signaling 0.013 0.0044 0.0064
Giardia lamblia Kinase, NEK 0.0307 0.085 0.2834
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0307 0.085 0.8049
Trichomonas vaginalis STE family protein kinase 0.0144 0.0107 0.0474
Schistosoma mansoni serine/threonine protein kinase 0.0642 0.2376 0.4094
Brugia malayi tRNA modification GTPase TrmE family protein 0.013 0.0044 0.004
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0304 0.0834 0.1007
Onchocerca volvulus 0.0239 0.054 0.0962
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1059 0.4274 0.4258
Echinococcus multilocularis Immunoglobulin 0.019 0.0314 0.0374
Brugia malayi Protein kinase domain containing protein 0.0138 0.0082 0.0081
Echinococcus granulosus serine threonine protein kinase nrc 0.0321 0.0914 0.0889
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0458 0.1538 0.1864
Loa Loa (eye worm) hypothetical protein 0.0225 0.0476 0.0518
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0201 0.0367 0.1612
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.0301 0.132
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0582 0.2099 0.2284
Entamoeba histolytica protein kinase, putative 0.0159 0.0175 0.0439
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0227 0.0485 0.4114
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0735
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0254 0.0607 0.0731
Brugia malayi putative serine/threonine kinase SADA gamma 0.0201 0.0367 0.0392
Echinococcus granulosus epidermal growth factor receptor 0.092 0.364 0.3623
Echinococcus granulosus protein kinase C gamma type 0.0441 0.1458 0.1434
Loa Loa (eye worm) hypothetical protein 0.0185 0.0294 0.032
Echinococcus granulosus cGMP dependent protein kinase 0.0304 0.0834 0.0809
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.029 0.0773 0.262
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0254 0.0607 0.1038
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Echinococcus multilocularis tyrosine protein kinase shark 0.0724 0.2749 0.3339
Schistosoma mansoni tyrosine kinase 0.1023 0.4112 0.7093
Schistosoma mansoni growth factor receptor-bound protein 0.0224 0.0469 0.0798
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0227 0.0485 0.2052
Schistosoma mansoni tyrosine kinase 0.0811 0.3144 0.542
Echinococcus granulosus geminin 0.0197 0.0349 0.0323
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0225 0.0477 0.0572
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0321 0.0914 0.0889
Trypanosoma brucei SNF1-related protein kinases, putative 0.0201 0.0367 0.1521
Loa Loa (eye worm) hypothetical protein 0.0254 0.0607 0.0661
Plasmodium falciparum cGMP-dependent protein kinase 0.0304 0.0834 0.7382
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1361 0.565 0.6149
Trypanosoma brucei polo-like protein kinase 0.0612 0.2238 0.9912
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0503 0.1741 0.1895
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0183 0.0285 0.0338
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1121 0.4557 0.554
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0307 0.085 0.303
Schistosoma mansoni ephrin receptor 0.0145 0.0109 0.0176
Echinococcus granulosus tyrosine kinase 0.0439 0.145 0.1427
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Loa Loa (eye worm) AGC/NDR protein kinase 0.0348 0.1034 0.1125
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0122 0.0007 0.0031
Echinococcus multilocularis roundabout 2 0.0126 0.0027 0.0024
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0348 0.1034 0.1251
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0837 0.1434
Onchocerca volvulus 0.029 0.0773 0.1415
Echinococcus multilocularis dual specificity 0.0314 0.088 0.1062
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0439 0.145 0.1427
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0225 0.0477 0.052
Echinococcus granulosus serine:threonine protein kinase 3 0.0582 0.2099 0.2078
Trypanosoma brucei cdc2-related kinase 3 0.0268 0.0671 0.2885
Echinococcus multilocularis cyclin dependent kinase 5 0.0268 0.0671 0.0808
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1017 0.4083 0.4443
Loa Loa (eye worm) hypothetical protein 0.042 0.1362 0.1482
Echinococcus multilocularis serine:threonine protein kinase N2 0.0295 0.0793 0.0957
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0227 0.0485 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Echinococcus multilocularis casein kinase ii subunit alpha 0.0225 0.0477 0.0573
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.013 0.0044 0.0064
Schistosoma mansoni protein kinase 0.0182 0.0278 0.0469
Echinococcus multilocularis activin receptor type 0.0182 0.0278 0.033
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0027 0.0035
Entamoeba histolytica protein kinase, putative 0.0159 0.0175 0.0439
Trichomonas vaginalis AGC family protein kinase 0.0328 0.0947 0.4194
Loa Loa (eye worm) SH2 domain-containing protein 0.013 0.0044 0.0048
Echinococcus granulosus tensin C1 domain containing phosphatase 0.013 0.0044 0.0017
Schistosoma mansoni protein kinase 0.0535 0.1887 0.325
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0127 0.0027 0.5
Loa Loa (eye worm) hypothetical protein 0.1361 0.565 0.6149
Loa Loa (eye worm) TK protein kinase 0.0798 0.3087 0.3359
Trypanosoma brucei Casein kinase II 0.0225 0.0477 0.2018
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.0947 0.1624
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0321 0.0914 0.8734
Schistosoma mansoni hypothetical protein 0.0232 0.0505 0.0861
Echinococcus granulosus mitogen activated protein kinase 11 0.0359 0.1088 0.1064
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0327 0.0939 0.0914
Onchocerca volvulus 0.0325 0.0929 0.1718
Echinococcus multilocularis tensin 0.013 0.0044 0.0045
Echinococcus multilocularis casein kinase I alpha 0.0245 0.0566 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Brugia malayi Sex muscle abnormal protein 5 0.0224 0.0469 0.0503
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0188 0.0308 0.0335
Echinococcus granulosus casein kinase I delta 0.0245 0.0566 0.054
Mycobacterium ulcerans hypothetical protein 0.0231 0.0503 1
Giardia lamblia Aurora kinase 0.0328 0.0947 0.3333
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0255 0.0611 0.2707
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0127 0.0027 0.5
Echinococcus multilocularis rho associated protein kinase 0.0737 0.2806 0.3408
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Giardia lamblia Kinase, CMGC CDK 0.0268 0.0671 0.1907
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0227 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0527 0.1851 0.2014
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0188 0.0308 0.0156
Echinococcus granulosus roundabout 2 0.0316 0.089 0.0866
Loa Loa (eye worm) hypothetical protein 0.044 0.1454 0.1583
Echinococcus multilocularis survival motor neuron protein 1 0.0275 0.0705 0.0849
Schistosoma mansoni tyrosine kinase 0.018 0.0272 0.0457
Entamoeba histolytica PH domain containing protein kinase, putative 0.0275 0.0704 0.2015
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0182 0.028 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1031 0.177
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0321 0.0914 0.8439
Loa Loa (eye worm) TK/ALK protein kinase 0.0646 0.2394 0.2606
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0532 0.1875 0.2274
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0314 0.088 0.3911
Brugia malayi Protein kinase domain containing protein 0.0799 0.309 0.3358
Loa Loa (eye worm) hypothetical protein 0.0315 0.0887 0.0965
Echinococcus multilocularis serine:threonine protein kinase N2 0.0642 0.2376 0.2884
Entamoeba histolytica protein kinase, putative 0.0328 0.0947 0.274
Leishmania major protein kinase, putative 0.0347 0.1031 0.4541
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0939 0.3726 0.3709
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0532 0.1873 0.2272
Schistosoma mansoni shc transforming protein 0.013 0.0044 0.0064
Loa Loa (eye worm) hypothetical protein 0.0274 0.07 0.0762
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0532 0.1875 0.2274
Plasmodium vivax serine/threonine protein kinase, putative 0.0187 0.0301 0.2136
Toxoplasma gondii histone kinase SNF1, putative 0.0201 0.0367 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.0749 0.3318
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0341 0.1002 0.1091
Schistosoma mansoni serine/threonine protein kinase 0.042 0.1364 0.2345
Echinococcus granulosus cyclin dependent kinase 5 0.0268 0.0671 0.0646
Toxoplasma gondii CMGC kinase, CK2 family 0.0225 0.0477 0.1054
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0182 0.028 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0417 0.1351 0.2322
Echinococcus granulosus serine/threonine protein kinase 0.0342 0.1006 0.0982
Schistosoma mansoni tyrosine kinase 0.0811 0.3144 0.542
Brugia malayi P38 map kinase family protein 2 0.0359 0.1088 0.1177
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0188 0.0308 0.1269
Schistosoma mansoni adapter molecule crk 0.0224 0.0469 0.0798
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0327 0.0939 0.1134
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0264 0.0653 0.0704
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0831 0.3237 0.3522
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.013 0.0044 0.0045
Echinococcus multilocularis casein kinase I delta 0.0245 0.0566 0.068
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0939 0.3726 0.4527
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0799 0.309 0.3358
Loa Loa (eye worm) TK protein kinase 0.0654 0.2428 0.2642
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Brugia malayi Protein kinase domain containing protein 0.0438 0.1446 0.1568
Schistosoma mansoni hypothetical protein 0.013 0.0044 0.0064
Onchocerca volvulus 0.0239 0.054 0.0962
Entamoeba histolytica protein kinase domain containing protein 0.0182 0.0278 0.0748
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0491 0.1687 0.1836
Onchocerca volvulus 0.0664 0.2474 0.4716
Schistosoma mansoni serine/threonine protein kinase 0.0577 0.208 0.3583
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.029 0.0773 0.3372
Echinococcus granulosus insulin receptor 0.1023 0.4112 0.4096
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1361 0.565 0.6149
Loa Loa (eye worm) AGC/PKN protein kinase 0.0642 0.2376 0.2586
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0201 0.0367 0.2839
Schistosoma mansoni titin 0.0158 0.0169 0.028
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0159 0.0175 0.0148
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0436 0.1437 0.1563
Loa Loa (eye worm) hypothetical protein 0.0239 0.054 0.0587
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0314 0.088 0.3821
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0492 0.1693 0.1837
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Trypanosoma cruzi polo-like protein kinase, putative 0.0612 0.2238 1
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Leishmania major casein kinase, putative 0.0245 0.0566 0.2436
Schistosoma mansoni vesicular amine transporter 0.019 0.0314 0.0531
Schistosoma mansoni protein kinase 0.0193 0.0331 0.0561
Brugia malayi Protein kinase domain containing protein 0.0239 0.054 0.058
Brugia malayi Protein kinase domain containing protein 0.0491 0.1687 0.1829
Echinococcus multilocularis myosin iiia 0.019 0.0317 0.0378
Echinococcus multilocularis mitogen activated protein kinase 3 0.0188 0.0308 0.0366
Brugia malayi Protein kinase domain containing protein 0.2138 0.9189 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0255 0.0611 0.2707
Echinococcus granulosus dual specificity protein kinase clk2 0.0347 0.1031 0.1007
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0612 0.2238 0.2717
Plasmodium falciparum calcium-dependent protein kinase 1 0.0227 0.0485 0.2743
Echinococcus multilocularis tyrosine protein kinase Srms 0.0439 0.145 0.1757
Loa Loa (eye worm) hypothetical protein 0.0325 0.0929 0.1011
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.148 0.2546
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0611 0.1044
Echinococcus granulosus tyrosine kinase 0.0239 0.054 0.0514
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0276 0.0706 0.3135
Brugia malayi probable protein kinase 0.06 0.2183 0.2369
Trypanosoma cruzi casein kinase, putative 0.0245 0.0566 0.2505
Entamoeba histolytica protein kinase, putative 0.0187 0.0301 0.0816
Entamoeba histolytica p21-activated kinase 0.0214 0.0424 0.1182
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0301 0.0509
Trichomonas vaginalis CAMK family protein kinase 0.0491 0.1687 0.747
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1059 0.4274 0.5195
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0027 0.0022
Loa Loa (eye worm) TK protein kinase 0.0439 0.145 0.1578
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0308 0.1364
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0559 0.1999 0.2425
Echinococcus multilocularis suppressor of cytokine signaling 7 0.013 0.0044 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0308 0.1364
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0671 0.1147
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0837 0.1434
Echinococcus multilocularis PAK box P21 Rho binding 0.0144 0.0107 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.1538 0.2646
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Entamoeba histolytica protein kinase , putative 0.0328 0.0947 0.274
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0536 0.189 0.2293
Schistosoma mansoni Neurotrimin precursor (hNT) 0.019 0.0314 0.0531
Schistosoma mansoni protein kinase 0.0328 0.0947 0.1624
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.013 0.0044 0.0017
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0276 0.0706 0.0769
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0359 0.1088 0.4755
Echinococcus granulosus glycogen synthase kinase 3 beta 0.029 0.0773 0.0748
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0285 0.126
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0371 0.1139 0.1115
Entamoeba histolytica protein kinase, putative 0.0596 0.2165 0.637
Entamoeba histolytica cell division protein kinase 2, putative 0.0268 0.0671 0.1917
Brugia malayi Protein kinase domain containing protein 0.1017 0.4083 0.4439
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0485 0.0826
Entamoeba histolytica PH domain containing protein kinase, putative 0.0275 0.0704 0.2015
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0458 0.1538 0.1515
Echinococcus multilocularis CDC7 cell division cycle 7 0.0202 0.037 0.0442
Trypanosoma brucei protein kinase, putative 0.029 0.0773 0.3343
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0317 0.1392
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.0331 0.0395
Plasmodium vivax serine/threonine kinase-1, putative 0.0347 0.1031 1
Schistosoma mansoni protein kinase 0.0245 0.0566 0.0966
Echinococcus granulosus CDC7 cell division cycle 7 0.0202 0.037 0.0344
Trypanosoma cruzi casein kinase, putative 0.0245 0.0566 0.2505
Entamoeba histolytica protein kinase 2, putative 0.0321 0.0914 0.2641
Echinococcus granulosus epidermal growth factor receptor 0.1393 0.5794 0.5783
Echinococcus multilocularis serine:threonine protein kinase 3 0.0582 0.2099 0.2547
Trichomonas vaginalis AGC family protein kinase 0.0255 0.0611 0.2706
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0182 0.028 0.0332
Echinococcus granulosus protein kinase 0.0346 0.1026 0.1002
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0458 0.1538 0.1674
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1677 0.2885
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.0749 0.3318
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0831 0.3237 0.3932
Echinococcus multilocularis 0.013 0.0044 0.0045
Schistosoma mansoni hypothetical protein 0.0232 0.0505 0.0861
Loa Loa (eye worm) hypothetical protein 0.1049 0.4226 0.4599
Onchocerca volvulus 0.0254 0.0607 0.1094
Loa Loa (eye worm) hypothetical protein 0.0315 0.0887 0.0965
Trichomonas vaginalis CMGC family protein kinase 0.0268 0.0671 0.2971
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0254 0.0607 0.1038
Echinococcus granulosus tyrosine protein kinase HCK 0.0309 0.0857 0.0832
Schistosoma mansoni cell adhesion molecule 0.0267 0.0666 0.1138
Loa Loa (eye worm) hypothetical protein 0.0255 0.0611 0.0665
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0371 0.1139 0.124
Schistosoma mansoni tyrosine kinase 0.0332 0.0965 0.1655
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0799 0.309 0.3753
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.1034 0.1775
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.029 0.0773 0.3433
Loa Loa (eye worm) CMGC/GSK protein kinase 0.029 0.0773 0.0841
Brugia malayi hypothetical protein 0.0239 0.054 0.058
Schistosoma mansoni protein kinase 0.0193 0.0331 0.0561
Leishmania major protein kinase A catalytic subunit isoform 1 0.0255 0.0611 0.264
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1031 0.177
Loa Loa (eye worm) hypothetical protein 0.0257 0.0622 0.0677
Brugia malayi Casein kinase II, alpha chain 0.0225 0.0477 0.0512
Brugia malayi Fes/CIP4 homology domain containing protein 0.0266 0.0662 0.0713
Echinococcus granulosus tyrosine protein kinase 0.0654 0.2428 0.2408
Brugia malayi serine/threonine protein kinase 6 0.0328 0.0947 0.1024
Entamoeba histolytica protein kinase, putative 0.0314 0.088 0.2539
Plasmodium falciparum glycogen synthase kinase 3 0.029 0.0773 0.6568
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.0331 0.0305
Echinococcus granulosus N chimaerin 0.0225 0.0477 0.0451
Plasmodium falciparum NIMA related kinase 1 0.0307 0.085 0.7595
Loa Loa (eye worm) casein kinase 0.0344 0.1019 0.1109
Echinococcus granulosus cyclin dependent kinase 0.0268 0.0671 0.0646
Onchocerca volvulus Tyrosine kinase homolog 0.1262 0.5198 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0268 0.0671 0.073
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0611 0.1044
Echinococcus granulosus calcium dependent protein kinase 0.0154 0.0153 0.0127
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0248 0.0582 0.0557
Leishmania major protein kinase A catalytic subunit 0.0255 0.0611 0.264
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0532 0.1875 0.2274
Plasmodium vivax unspecified product 0.0225 0.0477 0.4033
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.0301 0.1229
Brugia malayi Tyrosine-protein kinase abl-1 0.0291 0.0777 0.0838
Trypanosoma cruzi cdc2-related kinase 3 0.0268 0.0671 0.2975
Schistosoma mansoni ste20-related kinase 0.0464 0.1564 0.2691
Schistosoma mansoni serine/threonine protein kinase 0.0536 0.189 0.3255
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.1006 0.2917
Trichomonas vaginalis STE family protein kinase 0.0193 0.0331 0.1468
Echinococcus multilocularis casein kinase I alpha 0.0245 0.0566 0.068
Loa Loa (eye worm) hypothetical protein 0.0203 0.0375 0.0408
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.019 0.0317 0.1301
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Giardia lamblia Kinase, NEK 0.0307 0.085 0.2834
Loa Loa (eye worm) hypothetical protein 0.0254 0.0607 0.0661
Echinococcus granulosus casein kinase I delta 0.0245 0.0566 0.054
Schistosoma mansoni rap gtpase-activating protein 0.0254 0.0607 0.1038
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0489 0.1677 0.1654
Loa Loa (eye worm) SH2 domain-containing protein 0.013 0.0044 0.0048
Echinococcus granulosus tyrosine protein kinase Lyn 0.0605 0.2207 0.2186
Echinococcus granulosus tyrosine protein kinase Fyn 0.0532 0.1875 0.1853
Loa Loa (eye worm) protein-tyrosine phosphatase 0.013 0.0044 0.0048
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0201 0.0367 0.1534
Echinococcus multilocularis death associated protein kinase 1 0.1926 0.822 1
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0621
Entamoeba histolytica serine/threonine protein kinase, putative 0.0201 0.0367 0.1011
Brugia malayi Cam kinase protein 1 0.0227 0.0485 0.0521
Echinococcus granulosus dual specificity 0.0314 0.088 0.0855
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0225 0.0477 0.0451
Echinococcus granulosus raf serine:threonine protein kinase 0.0204 0.038 0.0354
Brugia malayi hypothetical protein 0.013 0.0044 0.004
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0359 0.1088 0.1184
Echinococcus granulosus serine:threonine protein kinase N2 0.0642 0.2376 0.2355
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0328 0.0947 0.1144
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Brugia malayi Protein kinase domain containing protein 0.0202 0.037 0.0396
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0347 0.1031 0.4591
Echinococcus multilocularis tyrosine protein kinase ABL1 0.071 0.2686 0.3262
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0929 0.3679 0.3662
Trypanosoma cruzi cdc2-related kinase 1 0.0268 0.0671 0.2975
Trichomonas vaginalis CMGC family protein kinase 0.029 0.0773 0.3423
Entamoeba histolytica casein kinase, putative 0.0225 0.0477 0.1341
Echinococcus granulosus tyrosine protein kinase Fyn 0.0532 0.1875 0.1853
Entamoeba histolytica protein kinase domain containing protein 0.0225 0.0477 0.1341
Brugia malayi intracellular kinase 0.029 0.0773 0.0834
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0596 0.2165 0.2357
Loa Loa (eye worm) AGC/AKT protein kinase 0.0616 0.2258 0.2457
Echinococcus granulosus casein kinase I alpha 0.0245 0.0566 0.054
Echinococcus granulosus protein kinase shaggy 0.029 0.0773 0.0748
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0245 0.0566 0.0616
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.029 0.0773 0.0932
Echinococcus granulosus growth factor receptor bound protein 2 0.0228 0.049 0.0464
Toxoplasma gondii AGC kinase 0.0255 0.0611 0.1762
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0255 0.0611 0.2707
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0159 0.0175 0.0204
Echinococcus granulosus fibroblast growth factor receptor 4 0.0559 0.1999 0.1977
Toxoplasma gondii AGC kinase 0.0596 0.2165 1
Schistosoma mansoni tyrosine kinase 0.0559 0.1999 0.3442
Trypanosoma cruzi cdc2-related kinase 1 0.0268 0.0671 0.2975
Brugia malayi protein unc-22 0.0158 0.0169 0.0177
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0201 0.0367 0.0399
Giardia lamblia Kinase, AGC PKA 0.0321 0.0914 0.3162
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0328 0.0947 0.0922
Entamoeba histolytica protein kinase, putative 0.029 0.0773 0.2221
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0182 0.028 0.0007
Brugia malayi Protein kinase domain containing protein 0.0435 0.1433 0.1553
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0532 0.1875 0.2274
Loa Loa (eye worm) hypothetical protein 0.0232 0.0505 0.055
Echinococcus multilocularis expressed conserved protein 0.0304 0.0834 0.1007
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0621
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0612 0.2238 0.2436
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0227 0.0485 0.4114
Loa Loa (eye worm) SH2 domain-containing protein 0.013 0.0044 0.0048
Echinococcus granulosus cGMP dependent protein kinase 1 0.0304 0.0834 0.0809
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Echinococcus granulosus tyrosine protein kinase shark 0.0724 0.2749 0.273
Echinococcus multilocularis tyrosine protein kinase HCK 0.0309 0.0857 0.1035
Brugia malayi serine/threonine-protein kinase plk-2 0.0612 0.2238 0.243
Echinococcus granulosus protein kinase c epsilon type 0.0446 0.148 0.1457
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0622 0.2756
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0984 0.3932 0.4778
Entamoeba histolytica protein kinase, putative 0.0616 0.2258 0.6646
Loa Loa (eye worm) CDC7 protein kinase 0.0202 0.037 0.0403
Brugia malayi Variant SH3 domain containing protein 0.0224 0.0469 0.0503
Trypanosoma cruzi Protein kinase B 0.0342 0.1006 0.4479
Brugia malayi Protein kinase domain containing protein 0.0183 0.0285 0.0302
Loa Loa (eye worm) hypothetical protein 0.0315 0.0887 0.0965
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Trypanosoma brucei aurora B kinase 0.0328 0.0947 0.4123
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.1031 0.4567
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.037 0.164
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0276 0.0706 0.3135
Entamoeba histolytica protein kinase, putative 0.0276 0.0706 0.2023
Schistosoma mansoni tensin-related 0.013 0.0044 0.0064
Entamoeba histolytica protein kinase, putative 0.0309 0.0857 0.2472
Onchocerca volvulus 0.0239 0.054 0.0962
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0308 0.1364
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0268 0.0671 0.2911
Loa Loa (eye worm) AGC/PKA protein kinase 0.0255 0.0611 0.0665
Loa Loa (eye worm) hypothetical protein 0.0224 0.0469 0.051
Schistosoma mansoni tyrosine kinase 0.0594 0.2156 0.3714
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.019 0.0317 0.0864
Trichomonas vaginalis STE family protein kinase 0.0193 0.0331 0.1468
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0199 0.0359 0.039
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.0331 0.0395
Brugia malayi ephrin receptor 1 precursor 0.0177 0.0259 0.0275
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0231 0.0504 0.0478
Echinococcus multilocularis N chimaerin 0.0225 0.0477 0.0572
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0187 0.0301 0.124
Trypanosoma cruzi casein kinase, putative 0.0245 0.0566 0.2505
Echinococcus multilocularis tyrosine protein kinase Blk 0.0439 0.145 0.1757
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.042 0.1364 0.1478
Schistosoma mansoni serine/threonine kinase 0.0348 0.1034 0.1775
Entamoeba histolytica casein kinase, putative 0.0245 0.0566 0.1604
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0027 0.0121
Brugia malayi serine/threonine-protein kinase 6 0.0328 0.0947 0.1024
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0837 0.1434
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0166 0.0206 0.0224
Echinococcus granulosus SH2 motif 0.013 0.0044 0.0017
Loa Loa (eye worm) hypothetical protein 0.0128 0.0035 0.0038
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0335 0.0975 0.1178
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0454 0.1519 0.1496
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0799 0.309 0.591
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0371 0.1139 0.1379
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0632 0.2801
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Schistosoma mansoni serine/threonine protein kinase 0.0314 0.088 0.1508
Loa Loa (eye worm) TK/ROR protein kinase 0.0158 0.0172 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0285 0.048
Brugia malayi Protein kinase domain containing protein 0.0239 0.054 0.058
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0799 0.309 0.3363
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0671 0.1147
Schistosoma mansoni protein kinase 0.0984 0.3932 0.6782
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0169 0.028
Entamoeba histolytica protein kinase, putative 0.0227 0.0485 0.1363
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Echinococcus granulosus cGMP dependent protein kinase 1 0.0304 0.0834 0.0809
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0255 0.0611 0.1762
Loa Loa (eye worm) hypothetical protein 0.0203 0.0375 0.0408
Schistosoma mansoni tyrosine kinase 0.0332 0.0965 0.1655
Onchocerca volvulus 0.0239 0.054 0.0962
Schistosoma mansoni serine/threonine protein kinase 0.0539 0.1905 0.3279
Onchocerca volvulus 0.0172 0.0234 0.037
Brugia malayi SH2 domain containing protein 0.0239 0.054 0.058
Brugia malayi map kinase activated protein kinase protein 2 0.0894 0.3521 0.3827
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0257 0.0622 0.0677
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0276 0.0706 0.3071
Entamoeba histolytica protein kinase, putative 0.0203 0.0375 0.1036
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.019 0.0314 0.0531
Echinococcus multilocularis calcium activated potassium channel 0.0304 0.0837 0.101
Loa Loa (eye worm) hypothetical protein 0.082 0.3183 0.3464
Echinococcus granulosus expressed conserved protein 0.013 0.0044 0.0017
Entamoeba histolytica protein kinase, putative 0.0616 0.2258 0.6646
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0984 0.3932 0.3915
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0317 0.1392
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0276 0.0706 0.3044
Schistosoma mansoni serine/threonine protein kinase 0.0274 0.0697 0.1192
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0299 0.0813 0.3601
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0255 0.0611 0.0658
Echinococcus granulosus Vam6:Vps39 protein 0.0254 0.0607 0.0582
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0254 0.0607 0.2691
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0224 0.0469 0.051
Trichomonas vaginalis AGC family protein kinase 0.0307 0.085 0.3766
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.037 0.164
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0188 0.0308 0.1269
Giardia lamblia Kinase, PLK 0.0612 0.2238 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0227 0.0485 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0632 0.2801
Brugia malayi cytokine inducible SH2-containing protein 5 0.013 0.0044 0.004
Brugia malayi Protein kinase domain containing protein 0.0372 0.1145 0.1239
Loa Loa (eye worm) hypothetical protein 0.041 0.132 0.1436
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0559 0.1999 0.1977
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0304 0.0834 0.1007
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0027 0.0029
Brugia malayi Stress-activated protein kinase jnk-1 0.0598 0.2176 0.2362
Loa Loa (eye worm) SRC-1 0.0532 0.1875 0.2041
Schistosoma mansoni nephrin 0.0126 0.0027 0.0035
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0027 0.003
Brugia malayi Protein kinase domain containing protein 0.0268 0.0671 0.0723
Plasmodium falciparum protein kinase 5 0.0268 0.0671 0.5212
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Trichomonas vaginalis AGC family protein kinase 0.0328 0.0947 0.4194
Trichomonas vaginalis STE family protein kinase 0.019 0.0317 0.1406
Giardia lamblia Kinase, CMGC MAPK 0.0188 0.0308 0.0034
Echinococcus multilocularis suppressor of cytokine signaling 7 0.013 0.0044 0.0045
Brugia malayi phosphofructokinase 0.0127 0.0027 0.0022
Schistosoma mansoni tyrosine kinase 0.092 0.364 0.6278
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0224 0.0469 0.051
Brugia malayi Protein kinase domain containing protein 0.1361 0.565 0.6146
Echinococcus granulosus tyrosine protein kinase ABL1 0.071 0.2686 0.2666
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.1741 0.2996
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1677 0.2885
Schistosoma mansoni suppressor of cytokine signaling 0.013 0.0044 0.0064
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0225 0.0477 0.0811
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0245 0.0566 0.0616
Echinococcus multilocularis aurora kinase A 0.0328 0.0947 0.1144
Brugia malayi Egg laying defective protein 4 0.0304 0.0834 0.0901
Echinococcus multilocularis neuroglian 0.0239 0.0539 0.0647
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Loa Loa (eye worm) hypothetical protein 0.0231 0.0504 0.0548
Loa Loa (eye worm) hypothetical protein 0.0201 0.0367 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0621
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0799 0.309 0.3071
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Entamoeba histolytica hypothetical protein 0.0276 0.0706 0.2023
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Brugia malayi Fibronectin type III domain containing protein 0.0225 0.0476 0.0511
Brugia malayi Protein kinase domain containing protein 0.1273 0.5247 0.5707
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0612 0.2238 0.2217
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0328 0.0947 0.274
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Schistosoma mansoni protein kinase 0.0436 0.1437 0.2471
Echinococcus multilocularis protein kinase shaggy 0.029 0.0773 0.0932
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0126 0.0027 0.0035
Brugia malayi Hr1 repeat family protein 0.0642 0.2376 0.258
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0227 0.0485 0.4114
Loa Loa (eye worm) hypothetical protein 0.0128 0.0035 0.0038
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0735
Entamoeba histolytica hypothetical protein 0.0864 0.3384 1
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0598 0.2176 0.2368
Brugia malayi hypothetical protein 0.0275 0.0705 0.076
Plasmodium vivax calcium-dependent protein kinase, putative 0.0227 0.0485 0.4114
Echinococcus granulosus hypothetical protein 0.0274 0.07 0.0675
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.1034 0.1775
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0027 0.0022
Echinococcus multilocularis tyrosine protein kinase 0.0654 0.2428 0.2948
Schistosoma mansoni hypothetical protein 0.0197 0.0349 0.0592
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Loa Loa (eye worm) hypothetical protein 0.0289 0.0768 0.0835
Echinococcus multilocularis epidermal growth factor receptor 0.1393 0.5794 0.7046
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0454 0.1519 0.1653
Echinococcus granulosus aurora kinase A 0.0328 0.0947 0.0922
Trypanosoma brucei cdc2-related kinase 1 0.0268 0.0671 0.2885
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0227 0.0485 0.1094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0609 0.2223 0.2414
Entamoeba histolytica protein kinase, putative 0.0187 0.0301 0.0816
Loa Loa (eye worm) TK/FAK protein kinase 0.1273 0.5247 0.571
Echinococcus granulosus casein kinase ii subunit alpha 0.0225 0.0477 0.0452
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0489 0.1677 0.2033
Schistosoma mansoni serine/threonine protein kinase 0.0799 0.309 0.5327
Plasmodium falciparum calcium-dependent protein kinase 5 0.0227 0.0485 0.2743
Plasmodium vivax protein kinase Crk2 0.0268 0.0671 0.6116
Toxoplasma gondii casein kinase I 0.0245 0.0566 0.1523
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0503 0.1741 0.1718
Schistosoma mansoni kinase 0.0654 0.2429 0.4186
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0278 0.1217
Schistosoma mansoni serine/threonine protein kinase 0.0894 0.3521 0.6072
Leishmania major protein kinase, putative 0.0347 0.1031 0.4541
Echinococcus granulosus serine:threonine protein kinase 0.0257 0.0622 0.0597
Loa Loa (eye worm) AGC/PKG protein kinase 0.0304 0.0834 0.0908
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0188 0.0308 0.1349
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0532 0.1875 0.2274
Trypanosoma brucei protein kinase, putative 0.0188 0.0308 0.1258
Trypanosoma cruzi polo-like protein kinase, putative 0.0612 0.2238 1
Schistosoma mansoni tyrosine kinase 0.1023 0.4112 0.7093
Loa Loa (eye worm) AUR protein kinase 0.0328 0.0947 0.1031
Echinococcus granulosus SHC transforming protein 3 0.013 0.0044 0.0017
Echinococcus granulosus expressed protein 0.0187 0.0301 0.0275
Loa Loa (eye worm) hypothetical protein 0.019 0.0314 0.0342
Brugia malayi casein kinase I 0.0245 0.0566 0.0609
Trichomonas vaginalis STE family protein kinase 0.0193 0.0331 0.1468
Loa Loa (eye worm) hypothetical protein 0.0195 0.0339 0.0369
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0532 0.1875 0.2274
Entamoeba histolytica serine/threonine protein kinase, putative 0.0612 0.2238 0.6587
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0158 0.0172 0.0145
Plasmodium falciparum serine/threonine protein kinase KIN 0.0201 0.0367 0.117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0027 0.0022
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0327 0.094 0.0916
Leishmania major protein kinase, putative 0.019 0.0317 0.1312
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Loa Loa (eye worm) hypothetical protein 0.015 0.0136 0.0148
Echinococcus multilocularis 6 phosphofructokinase 0.0127 0.0027 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0492 0.1693 0.1843
Echinococcus granulosus tyrosine protein kinase Fyn 0.0532 0.1875 0.1853
Entamoeba histolytica protein kinase domain containing protein 0.0328 0.0947 0.274
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0342 0.1006 0.4479
Schistosoma mansoni tensin 0.013 0.0044 0.0064
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0284 0.0745 0.3248
Brugia malayi serine/threonine kinase 12 0.0328 0.0947 0.1024
Schistosoma mansoni tensin 0.013 0.0044 0.0064
Echinococcus granulosus titin 0.0158 0.0169 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0239 0.054 0.1527
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0122 0.0007 0.0008
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0188 0.0308 0.1349
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0359 0.1088 0.4845
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0894 0.3521 0.3831
Schistosoma mansoni hypothetical protein 0.0197 0.0349 0.0592
Echinococcus multilocularis neuroglian 0.0126 0.0027 0.0024
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0193 0.0331 0.0305
Echinococcus multilocularis casein kinase I delta 0.0245 0.0566 0.068
Brugia malayi serine/threonine-protein kinase PAK 7 0.0525 0.1843 0.2
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0314 0.088 0.095
Brugia malayi Protein kinase domain containing protein 0.0239 0.054 0.058
Echinococcus multilocularis tyrosine kinase 0.0239 0.054 0.0649
Giardia lamblia Kinase, CAMK CAMKL 0.0201 0.0367 0.0337
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1444 0.6026 0.6558
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0268 0.0671 0.2079
Brugia malayi Protein kinase c protein 2 0.0261 0.0639 0.0688
Schistosoma mansoni neuroglian 0.0126 0.0027 0.0035
Brugia malayi Protein kinase domain containing protein 0.0417 0.1351 0.1464
Schistosoma mansoni protein kinase 0.0984 0.3932 0.6782
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0566 0.0966
Schistosoma mansoni tyrosine kinase 0.0532 0.1875 0.3228
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Echinococcus granulosus protein tyrosine kinase 0.1259 0.5185 0.5172
Trichomonas vaginalis STE family protein kinase 0.0307 0.085 0.3766
Brugia malayi Protein kinase domain containing protein 0.0831 0.3237 0.3518
Schistosoma mansoni serine/threonine protein kinase 0.0532 0.1873 0.3225
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0245 0.0566 0.0616
Schistosoma mansoni tyrosine kinase 0.0724 0.2749 0.4739
Giardia lamblia Kinase, CAMK CAMKL 0.0201 0.0367 0.0337
Echinococcus multilocularis serine:threonine protein kinase 38 0.0348 0.1034 0.1251
Trypanosoma brucei casein kinase I, isoform 2 0.0245 0.0566 0.2414
Entamoeba histolytica protein kinase, putative 0.0348 0.1034 0.3
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0254 0.0607 0.0582
Echinococcus granulosus mitogen activated protein kinase 3 0.0188 0.0308 0.0282
Loa Loa (eye worm) hypothetical protein 0.0225 0.0476 0.0518
Loa Loa (eye worm) hypothetical protein 0.019 0.0314 0.0342
Onchocerca volvulus 0.0737 0.2806 0.5359
Echinococcus multilocularis tensin 0.013 0.0044 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Loa Loa (eye worm) hypothetical protein 0.0545 0.1932 0.2103
Brugia malayi Variant SH3 domain containing protein 0.0225 0.0477 0.0511
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0348 0.1034 0.101
Onchocerca volvulus 0.0145 0.0113 0.0135
Trichomonas vaginalis AGC family protein kinase 0.0372 0.1145 0.5069
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0485 0.0582
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0245 0.0566 0.2505
Plasmodium vivax glycogen synthase kinase 3, putative 0.029 0.0773 0.7216
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0532 0.1875 0.1853
Giardia lamblia Kinase, CMGC GSK 0.029 0.0773 0.2435
Trichomonas vaginalis CMGC family protein kinase 0.0314 0.088 0.3895
Echinococcus granulosus dual specificity 0.0314 0.088 0.0855
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0268 0.0671 0.073
Plasmodium falciparum calcium-dependent protein kinase 2 0.0227 0.0485 0.2743
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.1006 0.1727
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0485 0.0582
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.037 0.164
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0159 0.0174 0.0148
Entamoeba histolytica protein kinase, putative 0.0183 0.0285 0.0766
Brugia malayi Tensin 0.013 0.0044 0.004
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0126 0.0027 0.0024
Onchocerca volvulus 0.1104 0.4478 0.8602
Echinococcus multilocularis serine:threonine protein kinase 0.0257 0.0622 0.0749
Schistosoma mansoni GTPase activating protein 0.013 0.0044 0.0064
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.092 0.364 0.3623
Leishmania major protein kinase, putative 0.0328 0.0947 0.4159
Echinococcus granulosus tyrosine protein kinase Src42A 0.0335 0.0975 0.095
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0439 0.145 0.1757
Brugia malayi p70 ribosomal S6 kinase beta 0.0596 0.2165 0.2351
Echinococcus granulosus twitchin 0.0312 0.087 0.0846
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0127 0.0027 0.5
Echinococcus granulosus SH2 motif 0.013 0.0044 0.0017
Brugia malayi Protein kinase domain containing protein 0.0187 0.0301 0.0321
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0598 0.2176 0.2641
Schistosoma mansoni nephrin 0.0274 0.0701 0.1199
Echinococcus multilocularis serine:threonine protein kinase N2 0.0348 0.1034 0.1251
Loa Loa (eye worm) hypothetical protein 0.0227 0.0485 0.0528
Plasmodium falciparum serine/threonine protein kinase, putative 0.0328 0.0947 0.8879
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.013 0.0044 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.1444 0.6026 0.6556
Trypanosoma cruzi casein kinase, putative 0.0245 0.0566 0.2505
Echinococcus granulosus c src tyrosine kinase 0.0332 0.0965 0.094
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0485 0.0582
Brugia malayi hypothetical protein 0.0225 0.0476 0.0511
Echinococcus multilocularis ephrin type A receptor 4 A 0.0254 0.0609 0.0733
Echinococcus granulosus hypothetical protein 0.013 0.0044 0.0017
Trichomonas vaginalis CK1 family protein kinase 0.0245 0.0566 0.2506
Brugia malayi Variant SH3 domain containing protein 0.0224 0.0469 0.0503
Schistosoma mansoni tensin-related 0.013 0.0044 0.0064
Echinococcus multilocularis mitogen activated protein kinase 14 0.0359 0.1088 0.1316
Trypanosoma cruzi casein kinase, putative 0.0245 0.0566 0.2505
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0268 0.0671 0.0646
Echinococcus multilocularis mitogen activated protein kinase 14 0.0359 0.1088 0.1316
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0621
Echinococcus granulosus serine:threonine protein kinase N2 0.0295 0.0793 0.0768
Echinococcus multilocularis casein kinase I gamma 0.0417 0.1351 0.1636
Loa Loa (eye worm) hypothetical protein 0.019 0.0317 0.0345
Echinococcus granulosus ephrin type A receptor 4 A 0.0254 0.0609 0.0584
Echinococcus granulosus Immunoglobulin 0.019 0.0314 0.0288
Echinococcus granulosus signal transduction protein lnk realted 0.013 0.0044 0.0017
Brugia malayi C1-like domain containing protein 0.0492 0.1693 0.1837
Trichomonas vaginalis CMGC family protein kinase 0.0268 0.0671 0.2971
Entamoeba histolytica protein kinase, putative 0.0164 0.02 0.0513
Echinococcus granulosus tensin 0.013 0.0044 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0706 0.1209
Loa Loa (eye worm) TK/EPH protein kinase 0.0294 0.0791 0.0861
Giardia lamblia Kinase, CDC7 0.0202 0.037 0.0356
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0612 0.2238 1
Schistosoma mansoni atypical protein kinase C 0.0645 0.2388 0.4114
Plasmodium falciparum calcium-dependent protein kinase 3 0.0227 0.0485 0.2743
Schistosoma mansoni hypothetical protein 0.0254 0.0607 0.1038
Schistosoma mansoni protein kinase 0.0984 0.3932 0.6782
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0532 0.1873 0.1851
Echinococcus multilocularis growth factor receptor bound protein 2 0.0224 0.0469 0.0562
Entamoeba histolytica casein kinase 1, putative 0.0245 0.0566 0.1604
Schistosoma mansoni serine/threonine kinase 0.0491 0.1687 0.2903
Echinococcus granulosus serine:threonine protein kinase 0.0257 0.0622 0.0597
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.042 0.1364 0.1341
Echinococcus multilocularis basement membrane specific heparan sulfate 0.019 0.0314 0.0374
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0126 0.0027 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0276 0.0706 0.2023
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Loa Loa (eye worm) TK protein kinase 0.0309 0.0857 0.0933
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0586
Brugia malayi MAP kinase sur-1 0.0188 0.0308 0.0328
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.013 0.0044 0.0045
Toxoplasma gondii aurora kinase 0.0328 0.0947 0.3542
Trichomonas vaginalis CK1 family protein kinase 0.0245 0.0566 0.2506
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0158 0.0169 0.0184
Loa Loa (eye worm) hypothetical protein 0.0145 0.0113 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0268 0.0671 0.2971
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.1519 0.2613
Trichomonas vaginalis CK1 family protein kinase 0.0245 0.0566 0.2506
Entamoeba histolytica protein kinase domain containing protein 0.0314 0.088 0.2539
Schistosoma mansoni serine/threonine protein kinase 0.0536 0.189 0.3255
Schistosoma mansoni tensin 0.013 0.0044 0.0064
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0586
Echinococcus granulosus dual specificity 0.0276 0.0706 0.0681
Onchocerca volvulus Serine\/threonine kinase homolog 0.0371 0.1139 0.2126
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2138 0.9189 1
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0347 0.1031 0.1122
Echinococcus multilocularis suppressor of cytokine signaling 6 0.013 0.0044 0.0045
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0201 0.0367 0.0438
Plasmodium falciparum casein kinase 1 0.0245 0.0566 0.3817
Entamoeba histolytica protein kinase domain containing protein 0.029 0.0773 0.2221
Trichomonas vaginalis STE family protein kinase 0.0193 0.0331 0.1468
Schistosoma mansoni serine/threonine protein kinase 0.0598 0.2176 0.3748
Echinococcus granulosus titin 0.0158 0.0169 0.0142
Onchocerca volvulus 0.0202 0.037 0.0634
Echinococcus granulosus casein kinase I alpha 0.0245 0.0566 0.054
Schistosoma mansoni serine/threonine protein kinase 0.0612 0.2238 0.3856
Echinococcus multilocularis serine:threonine protein kinase 0.0257 0.0622 0.0749
Schistosoma mansoni tyrosine kinase 0.1259 0.5185 0.8947
Echinococcus multilocularis casein kinase i 0.0245 0.0566 0.068
Onchocerca volvulus 0.0202 0.037 0.0634
Echinococcus granulosus serine:threonine kinase SAD 1 0.0201 0.0367 0.034
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0187 0.0301 0.0121
Echinococcus multilocularis SH2 motif 0.013 0.0044 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.029 0.0773 0.2221
Echinococcus multilocularis dual specificity protein kinase clk2 0.0347 0.1031 0.1247
Schistosoma mansoni protein kinase 0.0535 0.1887 0.325
Brugia malayi RhoGAP domain containing protein 0.0225 0.0477 0.0511
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Echinococcus multilocularis protein tyrosine kinase 0.1259 0.5185 0.6304
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0372 0.1145 0.1246
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0308 0.1364
Echinococcus multilocularis expressed protein 0.0187 0.0301 0.0358
Schistosoma mansoni cell adhesion molecule 0.0126 0.0027 0.0035
Echinococcus multilocularis protein kinase c iota type 0.0631 0.2325 0.2822
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Echinococcus granulosus protein kinase c iota type 0.0631 0.2325 0.2304
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0172 0.0234 0.1019
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0397 0.1261 0.1372
Brugia malayi Serine/threonine-protein kinase SULU 0.0503 0.1741 0.1888
Echinococcus multilocularis dual specificity 0.0314 0.088 0.1062
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Onchocerca volvulus 0.0245 0.0566 0.1013
Onchocerca volvulus 0.044 0.1454 0.2737
Trichomonas vaginalis CMGC family protein kinase 0.029 0.0773 0.3423
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0027 0.0091
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.042 0.1364 0.1652
Giardia lamblia Kinase, AGC AKT 0.0264 0.0653 0.1815
Echinococcus multilocularis 0.0346 0.1026 0.1241
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0187 0.0301 0.0328
Echinococcus granulosus SH2 domain containing adapter protein F 0.013 0.0044 0.0017
Echinococcus multilocularis SHC transforming protein 3 0.013 0.0044 0.0045
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0225 0.0477 0.0811
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0254 0.0607 0.26
Echinococcus multilocularis Glutaredoxin protein 5 0.0248 0.0582 0.07
Trichomonas vaginalis AGC family protein kinase 0.0616 0.2258 1
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0201 0.0367 0.1534
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0359 0.1088 0.4845
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0831 0.3237 0.3218
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0328 0.0947 0.274
Loa Loa (eye worm) TK protein kinase 0.0609 0.2223 0.2419
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.2238 0.9913
Echinococcus granulosus NCK adaptor protein 0.0224 0.0469 0.0443
Schistosoma mansoni tyrosine kinase 0.1393 0.5794 1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0489 0.1677 0.2033
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0255 0.0611 0.2707
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0188 0.0308 0.1349
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0227 0.0485 0.1094
Trypanosoma cruzi cdc2-related kinase 3 0.0268 0.0671 0.2975
Brugia malayi Immunoglobulin I-set domain containing protein 0.0225 0.0476 0.0511
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0308 0.052
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0347 0.1031 0.4591
Echinococcus multilocularis mitogen activated protein kinase 11 0.0359 0.1088 0.1316
Brugia malayi Temporarily assigned gene name protein 59 0.0254 0.0607 0.0654
Echinococcus multilocularis hypothetical protein 0.0232 0.0505 0.0607
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0535 0.1887 0.1866
Echinococcus granulosus tyrosine protein kinase Src64B 0.0532 0.1875 0.1853
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0539 0.1905 0.1883
Brugia malayi Protein kinase domain containing protein 0.0347 0.1031 0.1116
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0328 0.0947 0.9091
Echinococcus granulosus tyrosine protein kinase Blk 0.0439 0.145 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0458 0.1538 0.4501
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.038 0.0644
Brugia malayi SH2 domain containing protein 0.013 0.0044 0.004
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0254 0.0607 0.2691
Echinococcus multilocularis titin 0.0158 0.0169 0.0197
Loa Loa (eye worm) hypothetical protein 0.0326 0.0937 0.1019
Brugia malayi Kinase associated domain 1 family protein 0.0232 0.0505 0.0543
Brugia malayi protein kinase C II. 0.0446 0.148 0.1604
Echinococcus granulosus neuroglian 0.0239 0.0539 0.0513
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0285 0.031
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.0331 0.0305
Schistosoma mansoni tyrosine kinase 0.092 0.364 0.6278
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0304 0.0834 0.2945
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0328 0.0947 0.274
Echinococcus granulosus c-Jun N-terminal kinases 0.0598 0.2176 0.2155
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0227 0.0485 0.0459
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0347 0.1031 0.4591
Brugia malayi Furin-like cysteine rich region family protein 0.1393 0.5794 0.6303
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0255 0.0611 0.0735
Plasmodium falciparum protein serine/threonine kinase-1 0.0347 0.1031 1
Echinococcus multilocularis nervana 2 0.0248 0.0582 0.07
Loa Loa (eye worm) AUR protein kinase 0.0328 0.0947 0.1031
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0255 0.0611 0.5472
Trypanosoma cruzi aurora B kinase, putative 0.0328 0.0947 0.4213
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0255 0.0611 0.2617
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0454 0.1519 0.184
Trichomonas vaginalis AGC family protein kinase 0.0372 0.1145 0.5069
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.1006 0.2917
Loa Loa (eye worm) hypothetical protein 0.0325 0.0929 0.1011
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0255 0.0611 0.4417
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0278 0.1126
Echinococcus granulosus nervana 2 0.0248 0.0582 0.0557
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.013 0.0044 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0834 0.143
Schistosoma mansoni protein kinase 0.0144 0.0107 0.0173
Brugia malayi 6-phosphofructokinase 0.0127 0.0027 0.0022
Loa Loa (eye worm) CMGC/GSK protein kinase 0.029 0.0773 0.0841
Brugia malayi Protein kinase domain containing protein 0.0348 0.1034 0.1119
Loa Loa (eye worm) phosphofructokinase 0.0127 0.0027 0.003
Echinococcus granulosus casein kinase I alpha 0.0245 0.0566 0.054
Giardia lamblia Kinase, AGC PKA 0.0255 0.0611 0.1599
Echinococcus granulosus NDR protein kinase 0.0348 0.1034 0.101
Schistosoma mansoni tyrosine kinase 0.058 0.2093 0.3605
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0285 0.031
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0224 0.0469 0.0798
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0532 0.1875 0.1853
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0347 0.1031 0.4591
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0255 0.0611 0.2617
Brugia malayi Protein kinase domain containing protein 0.0436 0.1437 0.1557
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0227 0.0485 0.0459
Echinococcus granulosus suppressor of cytokine signaling 7 0.013 0.0044 0.0017
Giardia lamblia Kinase, CMGC CDK 0.0268 0.0671 0.1907
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Echinococcus granulosus SH2 domain containing protein 7 0.013 0.0044 0.0017
Onchocerca volvulus 0.0239 0.054 0.0962
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0477 0.2114
Echinococcus multilocularis rac serine:threonine kinase 0.0342 0.1006 0.1217
Echinococcus multilocularis 0.0395 0.1248 0.1511
Echinococcus granulosus cyclin dependent kinase 1 0.0268 0.0671 0.0646
Schistosoma mansoni vam6/vps39 related 0.0254 0.0607 0.1038
Echinococcus multilocularis SH2 motif 0.013 0.0044 0.0045
Echinococcus multilocularis dual specificity 0.0314 0.088 0.1062
Schistosoma mansoni serine/threonine protein kinase 0.1082 0.4377 0.7552
Brugia malayi Protein kinase domain containing protein 0.0654 0.2428 0.2637
Brugia malayi SH2 domain containing protein 0.0929 0.3679 0.4
Schistosoma mansoni cell adhesion molecule 0.0126 0.0027 0.0035
Brugia malayi Protein kinase domain containing protein 0.0257 0.0622 0.067
Echinococcus multilocularis signal transduction protein lnk realted 0.013 0.0044 0.0045
Entamoeba histolytica SH2 domain containing protein 0.013 0.0044 0.0049
Plasmodium vivax casein kinase 1, putative 0.0245 0.0566 0.4985
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.037 0.0628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0158 0.0169 0.0177
Onchocerca volvulus 0.042 0.1362 0.2557
Loa Loa (eye worm) hypothetical protein 0.028 0.0728 0.0793
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Trypanosoma brucei rac serine-threonine kinase, putative 0.0616 0.2258 1
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0359 0.1088 0.4798
Giardia lamblia Kinase, NEK 0.0307 0.085 0.2834
Giardia lamblia Kinase, STE STE20 0.019 0.0317 0.0083
Trypanosoma cruzi casein kinase II, putative 0.0225 0.0477 0.2109
Brugia malayi Doublecortin family protein 0.0341 0.1002 0.1084
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0539 0.1905 0.231
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0027 0.003
Echinococcus multilocularis roundabout 2 0.0126 0.0027 0.0024
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0348 0.1034 0.1251
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0485 0.2148
Schistosoma mansoni tyrosine kinase 0.0532 0.1875 0.3228
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0193 0.0331 0.0395
Loa Loa (eye worm) hypothetical protein 0.027 0.0682 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0834 0.143
Trichomonas vaginalis AGC family protein kinase 0.0348 0.1034 0.458
Onchocerca volvulus 0.0239 0.054 0.0962
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0489 0.1677 0.1654
Brugia malayi Protein kinase domain containing protein 0.1361 0.565 0.6146
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0188 0.0308 0.1349
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.042 0.1364 0.1484
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0027 0.0121
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0227 0.0485 0.1094
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0367 0.1623
Schistosoma mansoni ephrin receptor 0.0254 0.0609 0.1041
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0347 0.1031 0.4501
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1121 0.4557 0.4543
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0285 0.126
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0503 0.1741 0.2111
Entamoeba histolytica protein kinase, putative 0.023 0.0498 0.1402
Trichomonas vaginalis AGC family protein kinase 0.0328 0.0947 0.4194
Onchocerca volvulus Serine\/threonine kinase homolog 0.0612 0.2238 0.4258
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0268 0.0671 0.2911
Entamoeba histolytica protein kinase, putative 0.0328 0.0947 0.274
Entamoeba histolytica cell division protein kinase 2, putative 0.0268 0.0671 0.1917
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0255 0.0611 0.2617
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0332 0.0965 0.1655
Schistosoma mansoni signal transduction protein lnk-related 0.013 0.0044 0.0064
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0259 0.0632 0.0761
Brugia malayi Protein kinase domain containing protein 0.0239 0.054 0.058
Loa Loa (eye worm) hypothetical protein 0.082 0.3183 0.3464
Toxoplasma gondii AGC kinase 0.0255 0.0611 0.1762
Brugia malayi hypothetical protein 0.0254 0.0607 0.0654
Loa Loa (eye worm) hypothetical protein 0.0225 0.0476 0.0518
Loa Loa (eye worm) TK/INSR protein kinase 0.1023 0.4112 0.4475
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Leishmania major protein kinase, putative 0.0227 0.0485 0.207
Echinococcus multilocularis Immunoglobulin 0.019 0.0314 0.0374
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0314 0.088 0.3185
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.1006 0.1727
Echinococcus granulosus Glutaredoxin protein 5 0.0248 0.0582 0.0557
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0027 0.0035
Giardia lamblia Kinase, CMGC DYRK 0.0314 0.088 0.2985
Brugia malayi 6-phosphofructokinase 0.0127 0.0027 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0347 0.1031 0.399
Schistosoma mansoni protein kinase 0.0346 0.1026 0.1761
Loa Loa (eye worm) thyroid receptor interactor 0.0266 0.0662 0.072
Plasmodium vivax tyrosine kinase-like protein, putative 0.0182 0.028 0.1903
Brugia malayi Protein kinase domain containing protein 0.0616 0.2258 0.2452
Loa Loa (eye worm) TK/FER protein kinase 0.0239 0.054 0.0587
Echinococcus multilocularis geminin 0.0197 0.0349 0.0417
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0248 0.0582 0.07
Loa Loa (eye worm) hypothetical protein 0.013 0.0044 0.0048
Echinococcus multilocularis cyclin dependent kinase 1 0.0268 0.0671 0.0808
Schistosoma mansoni nck2/grb4 0.0224 0.0469 0.0798
Brugia malayi protein-tyrosine kinase 0.0439 0.145 0.1572
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.037 0.1136 0.1236
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0321 0.0914 0.4064
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0158 0.0172 0.02
Giardia lamblia Kinase, CMGC CK2 0.0225 0.0477 0.0909
Loa Loa (eye worm) TK/FER protein kinase 0.0929 0.3679 0.4004
Loa Loa (eye worm) protein kinase domain-containing protein 0.0417 0.1351 0.147
Brugia malayi Protein-tyrosine phosphatase containing protein 0.013 0.0044 0.004
Brugia malayi Temporarily assigned gene name protein 59 0.0293 0.0786 0.0848
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0126 0.0027 0.0024
Echinococcus multilocularis casein kinase I alpha 0.0245 0.0566 0.068
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0227 0.0485 0.0528
Echinococcus multilocularis roundabout 2 0.0316 0.089 0.1075
Echinococcus multilocularis NCK adaptor protein 0.0228 0.049 0.0588
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0532 0.1875 0.2274
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0225 0.0477 0.0519
Echinococcus multilocularis serine threonine protein kinase 0.0441 0.1458 0.1766
Echinococcus multilocularis SH2 domain containing protein 7 0.013 0.0044 0.0045

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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