Detailed information for compound 1374915

Basic information

Technical information
  • TDR Targets ID: 1374915
  • Name: 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrr olo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin -10-ylethanone chloride
  • MW: 528.88 | Formula: C26H20Cl3N3OS
  • H donors: 0 H acceptors: 1 LogP: 7.12 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N1c2ccccc2Sc2c1cccc2)C[n+]1cc(n2c1CCC2)c1ccc(c(c1)Cl)Cl.[Cl-]
  • InChi: 1S/C26H20Cl2N3OS.ClH/c27-18-12-11-17(14-19(18)28)22-15-29(25-10-5-13-30(22)25)16-26(32)31-20-6-1-3-8-23(20)33-24-9-4-2-7-21(24)31;/h1-4,6-9,11-12,14-15H,5,10,13,16H2;1H/q+1;/p-1
  • InChiKey: BGFUDTHFVLYPMU-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone chloride
  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-(10-phenothiazinyl)ethanone chloride
  • SMR000220459
  • 3-(3,4-Dichloro-phenyl)-1-(2-oxo-2-phenothiazin-10-yl-ethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium
  • MLS000580307

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Candida albicans Major Facilitator Transporter Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Mus musculus transient receptor potential cation channel, subfamily C, member 4 Starlite/ChEMBL No references
Homo sapiens thyroid hormone receptor, beta Starlite/ChEMBL No references
Homo sapiens glucosidase, alpha Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Candida albicans Major Facilitator Transporter Get druggable targets OG5_133773 All targets in OG5_133773
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus granulosus transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum ko:K08362 nuclear receptor, subfamily 1, group A, member 2, putative Get druggable targets OG5_134830 All targets in OG5_134830
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni hypothetical protein Get druggable targets OG5_134830 All targets in OG5_134830
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_134830 All targets in OG5_134830
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma mansoni transient receptor potential channel 4 Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis thyroid hormone receptor alpha Get druggable targets OG5_134830 All targets in OG5_134830
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus multilocularis TRP (transient receptor potential) channel Get druggable targets OG5_128782 All targets in OG5_128782
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Major Facilitator Transporter Get druggable targets OG5_133773 All targets in OG5_133773
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus TRP transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi Transient-receptor-potential like protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum Transient receptor potential-gamma protein, putative Get druggable targets OG5_128782 All targets in OG5_128782
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi photoreceptor-specific nuclear receptor thyroid hormone receptor, beta 461 aa 414 aa 24.6 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Echinococcus multilocularis short transient receptor potential channel 6 transient receptor potential cation channel, subfamily C, member 4 890 aa 799 aa 31.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0005 0.0003
Echinococcus granulosus cpg binding protein 0.0031 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0133
Trypanosoma cruzi malate dehydrogenase, putative 0.0231 0.2805 0.2801
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.016 0.0158
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Plasmodium vivax vivapain-3 0.0008 0.0026 0.003
Toxoplasma gondii lactate dehydrogenase LDH2 0.054 0.6655 1
Schistosoma mansoni transient receptor potential channel 0.0117 0.1383 0.1381
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Onchocerca volvulus 0.0016 0.0123 0.0424
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0012 0.0071 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0078 0.089 0.0888
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0074 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.025 0.0248
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0005 0.0003
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.0166 0.0241
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0464 0.1479
Mycobacterium ulcerans hypothetical protein 0.0023 0.0207 0.0651
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0163 0.0237
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Schistosoma mansoni zinc finger protein 0.0017 0.0131 0.0129
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0057 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0021 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Schistosoma mansoni Smad4 0.001 0.0044 0.0042
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0074 0.0246
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0464 0.0462
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0026 0.0024
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Onchocerca volvulus 0.0016 0.0123 0.0424
Schistosoma mansoni ferritin 0.0008 0.0024 0.0022
Brugia malayi lactate dehydrogenase. 0.054 0.6655 0.6654
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0135 0.0195
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Schistosoma mansoni alpha glucosidase 0.0044 0.0466 0.0464
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0753 0.0751
Plasmodium vivax SET domain protein, putative 0.0029 0.0289 0.0426
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Echinococcus granulosus bloom syndrome protein 0.0029 0.0283 0.0281
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.016 0.0158
Onchocerca volvulus 0.0016 0.0123 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0289 0.0287
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0133
Loa Loa (eye worm) MBCTL1 0.0066 0.0739 0.0737
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Brugia malayi Bromodomain containing protein 0.0084 0.0968 0.0966
Schistosoma mansoni hypothetical protein 0.0017 0.0131 0.0129
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0465 0.0463
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0123 0.0118
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0464 0.1356
Onchocerca volvulus 0.0012 0.0074 0.0246
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0207 0.0597
Trichomonas vaginalis esterase, putative 0.0043 0.0464 0.1494
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0464 0.1356
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0473
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0124 0.0122
Echinococcus multilocularis zinc finger protein 0.0023 0.0209 0.0207
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Echinococcus multilocularis cathepsin L 0.0008 0.0026 0.0024
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Brugia malayi nuclear hormone receptor 0.0012 0.0074 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0473
Plasmodium vivax malate dehydrogenase, putative 0.054 0.6655 1
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Trichomonas vaginalis malate dehydrogenase, putative 0.0231 0.2805 0.9034
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.016 0.0232
Echinococcus multilocularis Smad4 0.001 0.0044 0.0042
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0024 0.0059
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0255 0.3105 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0522 0.052
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0249 0.3023 0.3019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0071 0.0069
Plasmodium falciparum malate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Leishmania major malate dehydrogenase, putative 0.0231 0.2805 0.2801
Echinococcus granulosus ferritin 0.0008 0.0024 0.0022
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0044 0.0042
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Loa Loa (eye worm) hypothetical protein 0.0058 0.064 0.0638
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Echinococcus multilocularis L lactate dehydrogenase 0.0309 0.3771 0.377
Schistosoma mansoni zinc finger protein 0.0023 0.0209 0.0207
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0123 0.0424
Loa Loa (eye worm) hypothetical protein 0.0146 0.1741 0.174
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis malate dehydrogenase, putative 0.0137 0.1626 0.5238
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0465 0.0463
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.1968
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0464 0.1356
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.016 0.0456
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0044 0.0042
Leishmania major malate dehydrogenase, putative 0.054 0.6655 0.6653
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0466 0.0464
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0024
Loa Loa (eye worm) ctsf protein 0.0016 0.0123 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0074 0.0072
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2032
Loa Loa (eye worm) fibroinase 0.0016 0.0123 0.0121
Schistosoma mansoni hypothetical protein 0.0395 0.4849 0.4848
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3104
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0024
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.1383 0.1381
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Toxoplasma gondii ABC1 family protein 0.0043 0.0464 0.0689
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0466 0.1501
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0289 0.0426
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.1383 0.1381
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0751
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Schistosoma mansoni ferritin 0.0008 0.0024 0.0022
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0074 0.0072
Onchocerca volvulus 0.0029 0.0289 0.102
Echinococcus granulosus neuropeptide receptor A26 0.0448 0.5514 0.5513
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0024 0.0054
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0475 0.0473
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0123 0.0121
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Loa Loa (eye worm) malate dehydrogenase 0.0249 0.3023 0.3022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0072
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0005 0.0018
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Loa Loa (eye worm) hypothetical protein 0.0117 0.1383 0.1381
Echinococcus multilocularis smad 0.001 0.0044 0.0042
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Echinococcus multilocularis expressed protein 0.0008 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.0283 0.0912
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.2375 0.2373
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0289 0.0287
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0074 0.0072
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma brucei ISWI complex protein 0.0017 0.0131 0.0126
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Echinococcus multilocularis ferritin 0.0008 0.0024 0.0022
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Onchocerca volvulus 0.0028 0.0268 0.0944
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0623 0.0928
Brugia malayi nuclear receptor NHR-88 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0205
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Schistosoma mansoni ferritin 0.0008 0.0024 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Schistosoma mansoni cpg binding protein 0.0031 0.0313 0.0312
Onchocerca volvulus 0.0016 0.0123 0.0424
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Onchocerca volvulus 0.0016 0.0123 0.0424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1719 0.1718
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.4849 0.4848
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0135 0.0383
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0808 1 1
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0464 0.1356
Schistosoma mansoni malate dehydrogenase 0.054 0.6655 0.6654
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Mycobacterium ulcerans beta-lactamase 0.0043 0.0464 0.1479
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0522 0.052
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0464 0.0462
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0074 0.0072
Trypanosoma brucei cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0133
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0074 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0074 0.0072
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Loa Loa (eye worm) hypothetical protein 0.0042 0.0447 0.0445
Schistosoma mansoni cpg binding protein 0.0028 0.0268 0.0266
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.0638
Giardia lamblia Malate dehydrogenase 0.0255 0.3105 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Echinococcus granulosus expressed protein 0.0008 0.0024 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2436 0.2435
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0133
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0024 0.0059
Trypanosoma cruzi cysteine protease, putative 0.0008 0.0026 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0074 0.0246
Trypanosoma cruzi cysteine peptidase, putative 0.0008 0.0026 0.002
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0024 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0072
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Schistosoma mansoni hypothetical protein 0.0438 0.5379 0.5379
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0008 0.0026 0.002
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0055
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Entamoeba histolytica cysteine protease, putative 0.0016 0.0123 0.0177
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0464 0.0689
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Brugia malayi hypothetical protein 0.0035 0.0357 0.0355
Schistosoma mansoni DNA helicase recq1 0.0012 0.0071 0.0069
Echinococcus multilocularis bloom syndrome protein 0.0029 0.0283 0.0281
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0526 0.052
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Chlamydia trachomatis malate dehydrogenase 0.0255 0.3105 1
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0115 0.037
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0022
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0074 0.0072
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0753 0.1124
Loa Loa (eye worm) beta-lactamase 0.0043 0.0464 0.0462
Onchocerca volvulus 0.0043 0.0464 0.165
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0123 0.0121
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3385 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Loa Loa (eye worm) hypothetical protein 0.0066 0.0739 0.0737
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni hypothetical protein 0.0035 0.0357 0.0355
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0067 0.0065
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0739 0.0737
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Onchocerca volvulus 0.0023 0.0207 0.0726
Echinococcus granulosus zinc finger protein 0.0023 0.0209 0.0207
Schistosoma mansoni L-lactate dehydrogenase 0.054 0.6655 0.6654
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0124 0.0428
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0042
Schistosoma mansoni coup transcription factor 0.0012 0.0074 0.0072
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0123 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0753 0.2211
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0042
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Echinococcus granulosus L lactate dehydrogenase 0.0309 0.3771 0.377
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.197 0.1968
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0739 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0122
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0207 0.0651
Leishmania major cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.064 0.0638
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni cpg binding protein 0.0031 0.0313 0.0312
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0074 0.0072
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0466 0.0464
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0751
Schistosoma mansoni DNA helicase recq5 0.0012 0.0071 0.0069
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0123 0.0118
Echinococcus granulosus cathepsin l1 0.0016 0.0123 0.0121
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Onchocerca volvulus 0.0016 0.0123 0.0424
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.016 0.0158
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0005 0.0018
Plasmodium falciparum cysteine proteinase falcipain 1 0.0008 0.0026 0.003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.0283 0.0281
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0044 0.0042
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0005 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0124 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0289 0.0287
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Trypanosoma cruzi malate dehydrogenase, putative 0.0249 0.3023 0.3019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Brugia malayi Bromodomain containing protein 0.0042 0.0446 0.0444
Loa Loa (eye worm) Smad1 0.001 0.0044 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Brugia malayi Pre-SET motif family protein 0.0202 0.2436 0.2435
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0072
Schistosoma mansoni smad 0.001 0.0044 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0473
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Plasmodium falciparum lactate dehydrogenase, putative 0.0231 0.2805 0.421
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.2752 0.2751
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0072
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.064 0.0638
Trichomonas vaginalis malate dehydrogenase, putative 0.0113 0.1326 0.4272
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0072
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0074 0.0246
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0074 0.0072
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.064 0.0638
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.016 0.0158
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0005 0.0003
Echinococcus granulosus cathepsin l1 0.0011 0.0057 0.0055
Onchocerca volvulus 0.0114 0.1341 0.4807
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium ulcerans hypothetical protein 0.0043 0.0464 0.1479
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0887
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0123 0.0177
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0887
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0115 0.0164
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.1817 0.1816
Plasmodium falciparum carbonic anhydrase 0.0438 0.5379 0.8082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.8235 0.8235
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.1968
Echinococcus granulosus Smad4 0.001 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0525 0.0523
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Echinococcus granulosus smad 0.001 0.0044 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0207 0.0597
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Leishmania major carbonic anhydrase-like protein 0.0808 1 1
Schistosoma mansoni ferritin 0.0008 0.0024 0.0022
Onchocerca volvulus 0.0016 0.0123 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2783 0.8962
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0055
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0464 0.1479
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0022
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Loa Loa (eye worm) hypothetical protein 0.004 0.0416 0.0415
Echinococcus granulosus cathepsin L 0.0008 0.0026 0.0024
Echinococcus granulosus cysteine protease 0.0008 0.0026 0.0024
Schistosoma mansoni bromodomain containing protein 0.0071 0.0808 0.0806
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Schistosoma mansoni malate dehydrogenase 0.0249 0.3023 0.3022
Brugia malayi steroid hormone receptor 0.0012 0.0074 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0057 0.0055
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0753 0.0751
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0074 0.0072
Loa Loa (eye worm) oxidoreductase 0.0007 0.0005 0.0003
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.1334 0.1333
Loa Loa (eye worm) hypothetical protein 0.0045 0.0479 0.0477
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.052
Brugia malayi Smad1 0.001 0.0044 0.0042
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0005 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Toxoplasma gondii hypothetical protein 0.0438 0.5379 0.8082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0462
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0249 0.3023 0.3022
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1719 0.1718
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus microtubule associated protein 2 0.0667 0.8235 0.8235
Brugia malayi PHD-finger family protein 0.0029 0.0282 0.028
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3104
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0268 0.0266
Brugia malayi beta-lactamase 0.0043 0.0464 0.0462
Mycobacterium ulcerans malate dehydrogenase 0.0255 0.3105 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0623 0.0618
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Schistosoma mansoni hypothetical protein 0.0152 0.1817 0.1816
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0357 0.0355
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0669 0.0667
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.1334 0.1333
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0204 0.0202
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0163 0.0161
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0123 0.0121
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Brugia malayi ecdysteroid receptor 0.0012 0.0074 0.0072
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0022
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Onchocerca volvulus 0.0043 0.0464 0.165
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0055
Leishmania major hypothetical protein, conserved 0.0043 0.0464 0.0459
Toxoplasma gondii malate dehydrogenase MDH 0.054 0.6655 1
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0255 0.3105 0.3104
Entamoeba histolytica cysteine proteinase 2 0.0008 0.0026 0.003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0057 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Brugia malayi MH2 domain containing protein 0.0144 0.1719 0.1718
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Plasmodium vivax vivapain-1 0.0008 0.0026 0.003
Plasmodium falciparum L-lactate dehydrogenase 0.054 0.6655 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0123 0.0177
Loa Loa (eye worm) RecQ helicase 0.0029 0.0283 0.0281
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.025 0.0248
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0074 0.0072
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0012 0.0071 0.0098
Mycobacterium ulcerans lipase LipD 0.0043 0.0464 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0123 0.0177
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.025 0.0248
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Echinococcus multilocularis L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0074 0.0072
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni hypothetical protein 0.035 0.4288 0.4287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Brugia malayi isocitrate dehydrogenase 0.0019 0.016 0.0158
Plasmodium vivax unspecified product 0.0008 0.0026 0.003
Toxoplasma gondii cathepsin CPL 0.0016 0.0123 0.0177
Trichomonas vaginalis ferritin, putative 0.0008 0.0024 0.0076
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0135 0.0195
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Leishmania major hypothetical protein, conserved 0.0017 0.0131 0.0126
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0357 0.0355
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0239 0.0352
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Onchocerca volvulus 0.0229 0.2783 1
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0121
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.064 0.2284
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0808 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Echinococcus multilocularis carbonic anhydrase II 0.0808 1 1
Onchocerca volvulus 0.0011 0.0057 0.0184
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.016 0.0232
Echinococcus granulosus dnaJ subfamily B 0.0395 0.4849 0.4848
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Leishmania major malate dehydrogenase 0.0249 0.3023 0.3019
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Schistosoma mansoni L-lactate dehydrogenase 0.0231 0.2805 0.2804
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.064 0.0638
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus granulosus lactate dehydrogenase protein 0.054 0.6655 0.6654
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0135 0.0418
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0205
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0207 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0072
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0283 0.0912
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0268 0.0266
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0464 0.1356
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0074 0.0072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0074 0.0072
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.069 0.0685
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0124 0.0401
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.064 0.0638
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0231 0.2805 0.421
Loa Loa (eye worm) malate dehydrogenase 0.0255 0.3105 0.3104
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0357 0.0355
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0464 0.0459
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0072
Schistosoma mansoni hypothetical protein 0.0023 0.0204 0.0202
Brugia malayi Pre-SET motif family protein 0.0029 0.0289 0.0287
Leishmania major mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Entamoeba histolytica malate dehydrogenase, putative 0.054 0.6655 1
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0465 0.0463
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0022
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Echinococcus multilocularis lactate dehydrogenase protein 0.054 0.6655 0.6654
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0024 0.0054
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0153
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0464 0.1356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.8235 0.8235
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0522 0.052
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Brugia malayi CXXC zinc finger family protein 0.0028 0.0268 0.0266
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Brugia malayi cathepsin L-like precursor 0.0011 0.0057 0.0055
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Loa Loa (eye worm) carbonic anhydrase 3 0.0808 1 1
Schistosoma mansoni carbonic anhydrase 0.0438 0.5379 0.5379
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0207 0.0205
Loa Loa (eye worm) histone methyltransferase 0.001 0.0042 0.004
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0462
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0466 0.0461
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.0638
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Echinococcus multilocularis neuropeptide receptor A26 0.0448 0.5514 0.5513
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0074 0.0072
Trypanosoma brucei malate dehydrogenase-related 0.0231 0.2805 0.2801
Echinococcus multilocularis cpg binding protein 0.0031 0.0313 0.0312
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.2375 0.2373
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Echinococcus granulosus neuropeptide s receptor 0.0448 0.5514 0.5513
Trypanosoma brucei carbonic anhydrase-like protein 0.0808 1 1
Loa Loa (eye worm) hypothetical protein 0.054 0.6655 0.6654
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0042
Entamoeba histolytica malate dehydrogenase, putative 0.0255 0.3105 0.4661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) hypothetical protein 0.0074 0.084 0.0838
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0255 0.3105 0.4661
Echinococcus multilocularis neuropeptide s receptor 0.0448 0.5514 0.5513
Loa Loa (eye worm) hypothetical protein 0.0044 0.0465 0.0463
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Onchocerca volvulus 0.0058 0.064 0.2284
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Mycobacterium leprae Probable lipase LipE 0.0043 0.0464 0.1479
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.1383 0.1381
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0123 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0475 0.0473
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0753 0.0748
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Leishmania major glycosomal malate dehydrogenase 0.0249 0.3023 0.3019
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0074 0.0072
Treponema pallidum bacterioferrin (TpF1) 0.0008 0.0024 0.5
Trypanosoma brucei glucosidase, putative 0.0044 0.0466 0.0461
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Echinococcus granulosus carbonic anhydrase II 0.0808 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0462
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0044 0.0042
Plasmodium vivax lactate dehydrogenase 0.054 0.6655 1
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0044 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0074 0.0072
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.064 0.0638
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.2752 0.2751
Entamoeba histolytica cysteine proteinase 1, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) cysteine protease 0.0016 0.0123 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Onchocerca volvulus 0.0043 0.0464 0.165
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0003
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Toxoplasma gondii lactate dehydrogenase LDH1 0.054 0.6655 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0464 0.1356
Trypanosoma brucei glycosomal malate dehydrogenase 0.0249 0.3023 0.3019
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0466 0.1501
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0464 0.1479
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.052
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0207 0.0651
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.1817 0.1816
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0153
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0255 0.3105 0.917
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000006153 0.00000000019817
Brugia malayi Isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0074 0.0072
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0074 0.0072
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 0.014 uM PUBCHEM_BIOASSAY: Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1. (Class of assay: confirmatory) ChEMBL. No reference
EC50 (functional) 1.884 uM PUBCHEM_BIOASSAY: Confirmation dose response assay for compounds that inhibit transient receptor potential cation channel C4 (TRPC4). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2247, AID2256] ChEMBL. No reference
IC50 (functional) > 20 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485273, AID485343, AID493182] ChEMBL. No reference
Potency (functional) = 0.0316 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.4716 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 2.6169 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (binding) 199.5262 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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