Detailed information for compound 1405570

Basic information

Technical information
  • TDR Targets ID: 1405570
  • Name: STOCK5S-41079
  • MW: 480.361 | Formula: C22H19Cl2NO5S
  • H donors: 0 H acceptors: 4 LogP: 3.9 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)CN(C(=O)c1cc(=O)c2c(o1)cc(c(c2)Cl)C)C1CCS(=O)(=O)C1
  • InChi: 1S/C22H19Cl2NO5S/c1-13-8-20-17(9-18(13)24)19(26)10-21(30-20)22(27)25(16-6-7-31(28,29)12-16)11-14-2-4-15(23)5-3-14/h2-5,8-10,16H,6-7,11-12H2,1H3
  • InChiKey: ZZYGOIINWVWMDQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-Chloro-7-methyl-4-oxo-4H-chromene-2-carboxylic acid (4-chloro-benzyl)-(1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-amide
  • MLS000559489
  • SMR000149605

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens fatty acid synthase Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae Probable polyketide synthase Pks1 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Polyketide synthase Pks13 Get druggable targets OG5_126633 All targets in OG5_126633
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks8 Get druggable targets OG5_126633 All targets in OG5_126633
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks5 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB Get druggable targets OG5_126633 All targets in OG5_126633
Neospora caninum Soraphen polyketide synthase A, related Get druggable targets OG5_126633 All targets in OG5_126633
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) acyl carrier protein Get druggable targets OG5_126633 All targets in OG5_126633
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium parvum polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE Get druggable targets OG5_126633 All targets in OG5_126633
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae Polyketide synthase Pks13 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC Get druggable targets OG5_126633 All targets in OG5_126633
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium parvum type I fatty acid synthase Get druggable targets OG5_126633 All targets in OG5_126633
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Mycobacterium tuberculosis Polyketide synthase Pks12 Get druggable targets OG5_126633 All targets in OG5_126633
Loa Loa (eye worm) fatty acid synthase Get druggable targets OG5_126633 All targets in OG5_126633
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA Get druggable targets OG5_126633 All targets in OG5_126633
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126633 All targets in OG5_126633
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks7 Get druggable targets OG5_126633 All targets in OG5_126633
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA Get druggable targets OG5_126633 All targets in OG5_126633
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas Get druggable targets OG5_126633 All targets in OG5_126633
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126633 All targets in OG5_126633
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii type I fatty acid synthase, putative Get druggable targets OG5_126633 All targets in OG5_126633
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD Get druggable targets OG5_126633 All targets in OG5_126633
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 Get druggable targets OG5_126633 All targets in OG5_126633
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Polyketide synthase Pks2 Get druggable targets OG5_126633 All targets in OG5_126633
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA Get druggable targets OG5_126633 All targets in OG5_126633
Toxoplasma gondii type I fatty acid synthase, putative Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks1 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans polyketide synthase Pks13 Get druggable targets OG5_126633 All targets in OG5_126633
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein Get druggable targets OG5_126633 All targets in OG5_126633
Toxoplasma gondii type I fatty acid synthase Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans Type I modular polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans polyketide synthase Pks9 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks9 Get druggable targets OG5_126633 All targets in OG5_126633
Neospora caninum KR domain domain-containing protein, putative Get druggable targets OG5_126633 All targets in OG5_126633
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein Get druggable targets OG5_126633 All targets in OG5_126633
Onchocerca volvulus Fatty acid synthase homolog Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium tuberculosis Probable polyketide synthase Pks15 Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans Type I modular polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD Get druggable targets OG5_126633 All targets in OG5_126633
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans Type I modular polyketide synthase Get druggable targets OG5_126633 All targets in OG5_126633
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas Get druggable targets OG5_126633 All targets in OG5_126633
Toxoplasma gondii AMP-binding enzyme domain-containing protein Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE Get druggable targets OG5_126633 All targets in OG5_126633
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126633 All targets in OG5_126633
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB Get druggable targets OG5_126633 All targets in OG5_126633
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Brugia malayi nuclear hormone receptor 0.0019 0.0018 0.0126
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0091 0.0193 0.0189
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0156 0.0227
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0205
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0017 0.0644
Onchocerca volvulus 0.031 0.0725 0.6121
Toxoplasma gondii type I fatty acid synthase, putative 0.0021 0.0024 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.004 0.0547
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0399 0.0395
Mycobacterium ulcerans polyketide synthase 0.003 0.0045 0.0046
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0013 0.0009
Schistosoma mansoni hypothetical protein 0.008 0.0167 0.0657
Loa Loa (eye worm) DR-78 0.0019 0.0018 0.0157
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0058 0.0471
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0052
Loa Loa (eye worm) hypothetical protein 0.0081 0.0168 0.1451
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0068 0.0083
Mycobacterium ulcerans polyketide synthase Pks9 0.002 0.002 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0033 0.1731
Onchocerca volvulus 0.0064 0.0127 0.1048
Echinococcus multilocularis heat shock protein 90 0.0032 0.0049 0.0046
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.007 0.0267
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0687
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0687
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0033 0.0054
Echinococcus granulosus dnaJ subfamily B 0.0401 0.0949 0.3798
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0018 0.0058
Trypanosoma brucei glucosidase, putative 0.0039 0.0067 0.3455
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Entamoeba histolytica hypothetical protein 0.0073 0.015 0.221
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0024 0.0031 0.0017
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.007 0.0267
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0017 0.0687
Brugia malayi CXXC zinc finger family protein 0.0059 0.0116 0.0976
Echinococcus granulosus GPCR family 2 0.008 0.0167 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.015 0.0587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0282
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0073 0.0278
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0214 0.182
Onchocerca volvulus 0.0101 0.0219 0.1826
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Entamoeba histolytica hypothetical protein 0.0073 0.015 0.221
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0284 0.1125
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0011 0.0018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.007 0.0267
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0156 0.0252
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0167 0.0163
Schistosoma mansoni hypothetical protein 0.008 0.0167 0.0657
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.031 0.0479
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0032 0.0435
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0156 0.8044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0007 0.006
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.008 0.4057
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0017 0.0687
Loa Loa (eye worm) hypothetical protein 0.0254 0.0589 0.5088
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0018 0.0741
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.007 0.0267
Trypanosoma brucei heat shock protein 84, putative 0.0013 0.0004 0.0189
Schistosoma mansoni alpha glucosidase 0.0039 0.0067 0.0253
Toxoplasma gondii type I fatty acid synthase, putative 0.0033 0.0052 0.0085
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0011 0.0339
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.002 0.002 0.0005
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0013 0.0039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0068 0.734
Toxoplasma gondii pantoate-beta-alanine ligase 0.253 0.6129 1
Brugia malayi nuclear receptor RXR 0.0021 0.0024 0.0174
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.007 0.0267
Mycobacterium ulcerans polyketide synthase Pks13 0.0045 0.0081 0.0105
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0018 0.0126
Schistosoma mansoni heat shock protein 0.0032 0.0049 0.0184
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0016 0.0011 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.007 0.0267
Mycobacterium ulcerans hypothetical protein 0.0025 0.0032 0.0025
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.0399 0.1589
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Onchocerca volvulus 0.0076 0.0156 0.1291
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0032 0.002
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0032 0.005 0.0048
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0011 0.0018
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0049 0.0693
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0049 0.0081
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0033 0.003
Echinococcus granulosus endoplasmin 0.0025 0.0034 0.0121
Brugia malayi hypothetical protein 0.0019 0.0018 0.0126
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0156 0.0252
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0017 0.0052
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0032 0.1521
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0144
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0045 0.0082 0.0708
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Echinococcus multilocularis heat shock protein 90 0.0025 0.0034 0.003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0018 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0024 0.0174
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0024 0.002
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.007 0.0267
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Onchocerca volvulus 0.0099 0.0214 0.1781
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0068 0.308
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0055 0.0782
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0017 0.0863
Echinococcus multilocularis expressed conserved protein 0.0091 0.0193 0.0189
Schistosoma mansoni endoplasmin 0.0032 0.0049 0.0184
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0067 0.0576
Brugia malayi hypothetical protein 0.031 0.0725 0.6255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0156 0.1318
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0052
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0045 0.0046
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0017 0.0013 0.002
Brugia malayi nuclear receptor NHR-88 0.004 0.007 0.0576
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0007 0.006
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0687
Schistosoma mansoni hypothetical protein 0.008 0.0167 0.0657
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.007 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.007 0.0576
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0099 0.0212 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0205
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.008 0.068
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0091 0.0193 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0123 0.0119
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0091 0.0193 0.0287
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.031 0.0475
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0127 0.0496
Brugia malayi DnaJ domain containing protein 0.0066 0.0132 0.1116
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0664 1
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.0664 1
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0049 0.2565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Onchocerca volvulus 0.0497 0.1183 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0205
Brugia malayi Muscleblind-like protein 0.0162 0.0366 0.3141
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.028
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0196 0.1694
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0099 0.0212 0.3023
Mycobacterium ulcerans thioesterase TesA 0.0025 0.0033 0.0026
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0004 0.0006
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0034 0.0053
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0007 0.003
Schistosoma mansoni thyroid hormone receptor 0.004 0.007 0.0267
Echinococcus granulosus muscleblind protein 0.0162 0.0366 0.1457
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.007 0.0066
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0007 0.0185
Loa Loa (eye worm) hypothetical protein 0.0173 0.0394 0.3401
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0032 0.0025
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0024 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0825
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0055 0.287
Onchocerca volvulus 0.0035 0.0058 0.0461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0022
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0017 0.0687
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0011 0.0375
Echinococcus multilocularis cpg binding protein 0.0065 0.0129 0.0125
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.008 0.068
Echinococcus granulosus heat shock protein 0.0032 0.0049 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0073 0.0615
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.015 0.0587
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.007 0.0576
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0156 0.8081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Schistosoma mansoni endoplasmin 0.0032 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0068 0.0587
Plasmodium falciparum heat shock protein 90 0.0032 0.0049 0.2194
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0029 0.0043 0.2077
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0156 0.1318
Echinococcus granulosus heat shock protein 90 0.0025 0.0034 0.0121
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0156 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Echinococcus granulosus dnaJ subfamily C 6 0.0066 0.0132 0.0517
Schistosoma mansoni patched 1 0.0041 0.0073 0.0278
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0148
Brugia malayi Bromodomain containing protein 0.0038 0.0063 0.0517
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0211 0.0832
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0148
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0034 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Brugia malayi hypothetical protein 0.0021 0.0024 0.0174
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0017 0.0691
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.007 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0156 0.0252
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0029 0.0043 0.0067
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0018 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0007 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.009 0.0777
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0049 0.0693
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0308 0.0304
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.008 0.068
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0011 0.0557
Schistosoma mansoni zinc finger protein 0.0023 0.0027 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.044 0.372
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0017 0.0691
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.025
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0019
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0073 0.0069
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0068 0.0575
Brugia malayi nuclear receptor RXR 0.0019 0.0018 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0205
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0011 0.0028
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0018 0.0126
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0091 0.0193 0.076
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.007 0.0576
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0113
Schistosoma mansoni ap endonuclease 0.0039 0.0068 0.0258
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0099 0.0212 0.1797
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0196 0.0773
Schistosoma mansoni bromodomain containing protein 0.0065 0.0131 0.0513
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0278 0.0649 0.5592
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Echinococcus multilocularis protein dispatched 1 0.0047 0.0087 0.0083
Trichomonas vaginalis protein kinase inhibitor, putative 0.0066 0.0132 0.112
Loa Loa (eye worm) hypothetical protein 0.0041 0.0073 0.0629
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0196 0.0773
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0168 0.0164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.0045 0.0071
Schistosoma mansoni survival motor neuron protein 0.0099 0.0214 0.0844
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0067 0.3329
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0863
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.007 0.0564
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0034 0.0263
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0018 0.0157
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0018 0.0157
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0017 0.0644
Brugia malayi heat shock protein 90 0.0032 0.0049 0.0397
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0069 0.011
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0036
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0018 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0055 0.0468
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0034 0.0285
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0013
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0032 0.005 0.0053
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0011 0.0015
Leishmania major hypothetical protein, conserved 0.0076 0.0156 0.8044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0111
Mycobacterium leprae Probable lipase LipE 0.0076 0.0156 0.0222
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Schistosoma mansoni nuclear receptor 0.0019 0.0018 0.0058
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0055 0.009
Loa Loa (eye worm) hypothetical protein 0.008 0.0167 0.1444
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Schistosoma mansoni hypothetical protein 0.1035 0.2492 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0018 0.0058
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0058 0.0501
Onchocerca volvulus 0.0019 0.0018 0.0123
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0167 0.1417
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0049 0.0418
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0067 0.0563
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0004 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0013 0.0039
Loa Loa (eye worm) fatty acid synthase 0.003 0.0044 0.0381
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0018 0.0058
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.005 0.0053
Brugia malayi ecdysteroid receptor 0.004 0.007 0.0576
Schistosoma mansoni cpg binding protein 0.0065 0.0129 0.0504
Onchocerca volvulus 0.0019 0.0018 0.0123
Loa Loa (eye worm) hypothetical protein 0.0097 0.0207 0.1788
Schistosoma mansoni nuclear hormone receptor 0.004 0.007 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Echinococcus granulosus transcription factor btf3 0.0034 0.0055 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0024 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0032 0.0249
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0069 0.008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0067 0.0953
Schistosoma mansoni hypothetical protein 0.0173 0.0394 0.1567
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0049 0.2422
Mycobacterium ulcerans lipase LipD 0.0076 0.0156 0.0227
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.007 0.0576
Onchocerca volvulus 0.0049 0.009 0.0732
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0049 0.2422
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0004 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.004 0.007 0.0576
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.008 0.4057
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.007 0.0066
Leishmania major basic transcription factor 3a, putative 0.0034 0.0055 0.2732
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0017 0.0863
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.007 0.0066
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0018 0.0157
Schistosoma mansoni thyroid hormone receptor 0.004 0.007 0.0267
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0156 0.0152
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.007 0.0267
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.253 0.6129 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0074
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0058 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.1318
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.0399 0.3447
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0033 0.1571
Trichomonas vaginalis helicase, putative 0.0013 0.0005 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0156 0.8044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0148
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0014 0.0121
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.007 0.0267
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0207 0.0203
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0025 0.1116
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0024 0.0081
Entamoeba histolytica hypothetical protein 0.0073 0.015 0.221
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0308 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Schistosoma mansoni hypothetical protein 0.0073 0.015 0.0587
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0049 0.2194
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0394 0.3381
Brugia malayi beta-lactamase family protein 0.0076 0.0156 0.1319
Onchocerca volvulus 0.0025 0.0032 0.0244
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.007 0.0066
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0049 0.2422
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.1318
Echinococcus granulosus FTZ F1 alpha 0.004 0.007 0.0267
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0018 0.0058
Echinococcus granulosus cpg binding protein 0.0065 0.0129 0.0504
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0196 0.1668
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Mycobacterium ulcerans polyketide synthase 0.0032 0.005 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0068 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0011 0.0375
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0099 0.0212 0.1797
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0026 0.0195
Loa Loa (eye worm) steroid hormone receptor 0.004 0.007 0.0606
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0049 0.0427
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0018 0.0058
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.0949 0.0945
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0059 0.0116 0.0162
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0011 0.0375
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0067 0.0563
Echinococcus multilocularis dnaJ subfamily C 6 0.0066 0.0132 0.0129
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0058 0.0054
Schistosoma mansoni hypothetical protein 0.004 0.0069 0.0263
Echinococcus granulosus expressed conserved protein 0.0091 0.0193 0.076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.007 0.0606
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0017 0.0052
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0156 0.1319
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0168 0.066
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0156 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) acyl carrier protein 0.0014 0.0005 0.0047
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0029 0.0043 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.007 0.0576
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0214
Trichomonas vaginalis set domain proteins, putative 0.0497 0.1183 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.0018 0.0126
Schistosoma mansoni hypothetical protein 0.0401 0.0949 0.3798
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0116 0.1004
Trichomonas vaginalis endoplasmin, putative 0.002 0.0019 0.0165
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0034 0.1586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0067 0.0563
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0156 0.0612
Schistosoma mansoni heat shock protein 0.0032 0.0049 0.0184
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0031 0.0022
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0099 0.0212 0.1797
Brugia malayi nuclear hormone receptor 0.004 0.007 0.0576
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0156 0.0252
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0034 0.1586
Echinococcus multilocularis survival motor neuron protein 1 0.0487 0.1157 0.1154
Schistosoma mansoni hypothetical protein 0.008 0.0167 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.007 0.0576
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0017 0.0027
Schistosoma mansoni ap endonuclease 0.0039 0.0068 0.0258
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.003 0.0045 0.0071
Brugia malayi isocitrate dehydrogenase 0.0016 0.0011 0.0061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0156 0.1346
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0032 0.0051
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.007 0.0267
Entamoeba histolytica hypothetical protein 0.0034 0.0055 0.0782
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.008 0.0104
Schistosoma mansoni inositol monophosphatase 0.0045 0.008 0.0308
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0021 0.0183
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0007 0.0053
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0156 0.0222
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0032 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0437 0.1036 0.8951
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0068 0.0064
Echinococcus multilocularis heat shock protein 0.0032 0.0049 0.0046
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.003 0.0045 0.0041
Plasmodium falciparum endoplasmin, putative 0.002 0.0019 0.0757
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Echinococcus multilocularis FTZ F1 alpha 0.004 0.007 0.0066
Schistosoma mansoni cpg binding protein 0.0065 0.0129 0.0504
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.253 0.6129 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0032 0.002
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.008 0.4057
Plasmodium vivax endoplasmin, putative 0.0032 0.0049 0.2194
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0011 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.007 0.0606
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0068 0.308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0148
Brugia malayi glucose-6-phosphate dehydrogenase 0.0091 0.0193 0.164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.007 0.0267
Echinococcus multilocularis protein patched 0.0041 0.0073 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.007 0.0606
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0032 0.0249
Brugia malayi Endoplasmin precursor 0.0032 0.0049 0.0397
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0127 0.0124
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0034 0.0285
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0091 0.0193 0.076
Echinococcus granulosus zinc finger protein 0.0023 0.0027 0.0093
Brugia malayi hypothetical protein 0.0021 0.0024 0.0174
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0252
Echinococcus multilocularis tumor protein p63 0.0332 0.0779 0.0775
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.1318
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0167 0.0657
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0004 0.0031
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.007 0.0267
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0025 0.0032 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Echinococcus granulosus geminin 0.1035 0.2492 1
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Mycobacterium ulcerans beta-lactamase 0.0076 0.0156 0.0227
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0032 0.0435
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0091 0.0193 0.1666
Loa Loa (eye worm) inositol-1 0.0045 0.008 0.0695
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0032 0.0249
Echinococcus multilocularis transcription factor btf3 0.0034 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.031 0.0725 0.6267
Brugia malayi Bromodomain containing protein 0.0077 0.0159 0.1348
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0017 0.0687
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0068 0.0792
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0007 0.003
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0045 0.0046
Schistosoma mansoni zinc finger protein 0.0019 0.0018 0.0058
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0032 0.005 0.0079
Mycobacterium leprae Polyketide synthase Pks13 0.0045 0.0081 0.01
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0055 0.2732
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0055 0.0468
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0018 0.0015
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0687
Schistosoma mansoni hypothetical protein 0.1035 0.2492 1
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0049 0.2565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0168 0.066
Schistosoma mansoni hypothetical protein 0.004 0.0069 0.0263
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0013 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0049 0.2422
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0018 0.0015
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.007 0.0576
Brugia malayi conserved hypotetical protein 0.0019 0.0018 0.0126
Mycobacterium tuberculosis Probable thioesterase TesA 0.0025 0.0033 0.0051
Plasmodium vivax SET domain protein, putative 0.0064 0.0127 0.5915
Brugia malayi Inositol-1 0.0045 0.008 0.0665
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Loa Loa (eye worm) hypothetical protein 0.0069 0.0141 0.1216
Schistosoma mansoni nuclear receptor 0.0019 0.0018 0.0058
Brugia malayi beta-lactamase family protein 0.0076 0.0156 0.1319
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0548
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0018 0.0015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.007 0.0606
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0057 0.0111 0.0926
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.007 0.0576
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.002 0.0019 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.007 0.0267
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.005 0.0079
Schistosoma mansoni inositol monophosphatase 0.0045 0.008 0.0308
Trichomonas vaginalis heat shock protein, putative 0.002 0.0019 0.0165
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0022 0.0024 0.0037
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0017 0.0197
Schistosoma mansoni zinc finger protein 0.0015 0.0008 0.0019
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0018 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0252
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0013 0.0036
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0018 0.0058
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0055 0.2732
Echinococcus multilocularis muscleblind protein 1 0.0162 0.0366 0.0363
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Onchocerca volvulus Fatty acid synthase homolog 0.0054 0.0104 0.0849
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0067 0.0109
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0156 0.0612
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Onchocerca volvulus 0.004 0.007 0.0564
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0017 0.0197
Brugia malayi Pre-SET motif family protein 0.0064 0.0127 0.1071
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.025
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0589 0.5088
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0416 0.3518
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0099 0.0212 0.0347
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.007 0.0576
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0196 0.0773
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0024 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0011 0.0007
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0011 0.0061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0068 0.0109
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0067 0.0063
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0018 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0067 0.0953
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0017 0.0026
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0099 0.0212 1
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.003 0.0045 0.0041
Mycobacterium ulcerans thioesterase 0.0025 0.0033 0.0026
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.015 0.0146
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0032 0.1521
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0068 0.0558
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0067 0.0563
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0068 0.34
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0036
Onchocerca volvulus 0.0059 0.0116 0.0955
Entamoeba histolytica hypothetical protein 0.0025 0.0033 0.045
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0025 0.0033 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0863
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0011 0.0007
Onchocerca volvulus 0.0076 0.0156 0.1291
Entamoeba histolytica hypothetical protein 0.0073 0.015 0.221
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0018 0.0058
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0068 0.3525
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0013
Echinococcus granulosus survival motor neuron protein 1 0.0487 0.1157 0.4636
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0045 0.0081 0.013
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0091 0.0193 1
Brugia malayi hypothetical protein 0.0019 0.0018 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0049 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0196 0.0192
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0034 0.0285
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.0045 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0032 0.0025
Brugia malayi beta-lactamase 0.0076 0.0156 0.1319
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.0597
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Trypanosoma brucei ISWI complex protein 0.0015 0.0008 0.0435
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.0664 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0032 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.007 0.0576
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0007 0.006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0068 0.34
Toxoplasma gondii ABC1 family protein 0.0076 0.0156 0.0254
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.007 0.0267
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0257 0.0419
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.0416 0.3498
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0022 0.0191
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.031 0.0504
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0067 0.0563
Mycobacterium leprae Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.253 0.6129 1
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0024 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0399 0.0395
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0011 0.0007
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0034 0.0121
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0055 0.2475
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.009 0.0347
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0045 0.0046
Echinococcus multilocularis muscleblind protein 0.0162 0.0366 0.0363
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0067 0.0563
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0032 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0156 0.7286
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0127 0.0207
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0168 0.066
Schistosoma mansoni hypothetical protein 0.004 0.0069 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0049 0.2565
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.008 0.0308
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.008 0.1162
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0067 0.0563
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.007 0.0564
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0207 0.0817
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0068 0.0973
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0007 0.0185
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.084
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0091 0.0193 1
Schistosoma mansoni cpg binding protein 0.0059 0.0116 0.0452
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0649 0.5487
Mycobacterium ulcerans hypothetical protein 0.0076 0.0156 0.0227
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0032 0.1521
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0033 0.0119
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0034 0.0027
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0013 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0167 0.0657
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0483 0.1147 0.187
Schistosoma mansoni hypothetical protein 0.0066 0.0132 0.0517
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.007 0.0576
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.008 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0039
Onchocerca volvulus Bile acid receptor homolog 0.004 0.007 0.0564
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0196 0.0773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Schistosoma mansoni hypothetical protein 0.0099 0.0214 0.0844
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0022
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.008 0.0131
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0049 0.0507
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Loa Loa (eye worm) beta-lactamase 0.0076 0.0156 0.1346
Loa Loa (eye worm) DnaJ domain-containing protein 0.0066 0.0132 0.1144
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0068 0.0575
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0156 0.0252
Echinococcus granulosus tumor protein p63 0.0332 0.0779 0.3115
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0007 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0196 0.0192
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0278 0.0649 0.5606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) hypothetical protein 0.0162 0.0366 0.3163
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.007 0.0066
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0156 0.0227
Brugia malayi tailless protein 0.0019 0.0018 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0091 0.0193 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.1346
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0011 0.0557
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.028
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0156 0.0252
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0018 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0067 0.3329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0059 0.0116 0.019
Brugia malayi Pre-SET motif family protein 0.0437 0.1036 0.8948
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0034 0.003
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0034 0.1586
Echinococcus multilocularis GPCR, family 2 0.008 0.0167 0.0163
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0055 0.2475
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0031 0.0049 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.007 0.0576
Toxoplasma gondii exonuclease III APE 0.0039 0.0068 0.0111
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.007 0.0267
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0144
Schistosoma mansoni alpha-glucosidase 0.0151 0.0339 0.135
Schistosoma mansoni coup transcription factor 0.004 0.007 0.0267
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0067 0.0546
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0017 0.0687
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.007 0.0066
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0091 0.0193 0.2523
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0018 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0196 0.0773
Loa Loa (eye worm) hypothetical protein 0.0162 0.0366 0.3163
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0034 0.0122
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.008 0.0077
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0118 0.0461
Schistosoma mansoni hypothetical protein 0.004 0.0069 0.0263
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0055 0.0468
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0022
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.003 0.0045 0.0359
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0018 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0067 0.0563
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.007 0.0267
Brugia malayi Latrophilin receptor protein 2 0.008 0.0167 0.1417
Loa Loa (eye worm) hypothetical protein 0.0487 0.1157 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.0399 0.3426
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.007
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0207 0.3077
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0687
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0007 0.0371
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0032 0.005 0.0079
Echinococcus granulosus heat shock protein 90 0.0032 0.0049 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0167 0.1444
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0073 0.0278
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0007 0.0185
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0589 0.5073
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0067 0.0253
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0606
Giardia lamblia Grp94/Hsp90 0.0025 0.0034 0.0263
Schistosoma mansoni transcription factor btf3 0.0034 0.0055 0.0208
Trichomonas vaginalis esterase, putative 0.0076 0.0156 0.1318
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.007 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0039
Echinococcus multilocularis geminin 0.1035 0.2492 0.2489
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0034 0.0122
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0055 0.0478
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0011 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.007 0.0576
Echinococcus multilocularis endoplasmin 0.0025 0.0034 0.003
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0011 0.0028
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0018 0.0015
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.003 0.0045 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.007 0.0606
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0127 0.0496
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0067 0.0563
Brugia malayi ecdysone receptor 0.0019 0.0018 0.0126
Brugia malayi hypothetical protein 0.0073 0.015 0.1266
Onchocerca volvulus 0.006 0.0117 0.0961
Brugia malayi nuclear receptor NHR-67 0.0019 0.0018 0.0126
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0007 0.006
Brugia malayi steroid hormone receptor 0.004 0.007 0.0576
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0058 0.0217
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0073 0.0629
Brugia malayi CHE-14 protein 0.0041 0.0073 0.0599
Echinococcus multilocularis zinc finger protein 0.0023 0.0027 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Onchocerca volvulus 0.0076 0.0156 0.1291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0157
Loa Loa (eye worm) endoplasmin 0.0032 0.0049 0.0427
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0018 0.0126
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0664 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0032 0.0025
Brugia malayi PHD-finger family protein 0.0028 0.004 0.0311
Brugia malayi hypothetical protein 0.0487 0.1157 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0062
Mycobacterium leprae Probable polyketide synthase Pks1 0.0032 0.005 0.0048
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Leishmania major heat shock protein 83-1 0.0032 0.0049 0.2422
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0045 0.0081 0.013
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0068 0.0258
Trypanosoma brucei heat shock protein, putative 0.0032 0.0049 0.2565
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0033 0.0258
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.007 0.0576
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0011 0.0339
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0113
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0068 0.34
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0067 0.3329
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0123 0.0478
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.003 0.0045 0.2189
Brugia malayi beta-NAC-like protein 0.0034 0.0055 0.0448
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.008 0.417
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.007 0.0576
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0007 0.006
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.025
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0049 0.2422
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0032 0.0025
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0018 0.0126
Schistosoma mansoni alpha-glucosidase 0.0151 0.0339 0.135
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0207 0.1762
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.007 0.0606
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0167 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.044 0.372
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0863
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0032 0.005 0.0048
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0007 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0141
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0024 0.0031 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.007 0.0066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0589 0.5073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0664 0.5619
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0033 0.0119
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0022

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 10.6 uM PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 12.9 uM PubChem BioAssay. Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.2944 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (binding) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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