Detailed information for compound 1409667

Basic information

Technical information
  • TDR Targets ID: 1409667
  • Name: 3-methyl-N-(4-methyl-3-nitrophenyl)thiophene- 2-carboxamide
  • MW: 276.311 | Formula: C13H12N2O3S
  • H donors: 1 H acceptors: 3 LogP: 3.33 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1sccc1C)Nc1ccc(c(c1)[N+](=O)[O-])C
  • InChi: 1S/C13H12N2O3S/c1-8-3-4-10(7-11(8)15(17)18)14-13(16)12-9(2)5-6-19-12/h3-7H,1-2H3,(H,14,16)
  • InChiKey: WSGKNENCCOTIEG-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 3-methyl-N-(4-methyl-3-nitro-phenyl)thiophene-2-carboxamide
  • 3-methyl-N-(4-methyl-3-nitrophenyl)-2-thiophenecarboxamide
  • IVK/9162208
  • AK-968/40708691
  • MLS000698759
  • N-{3-nitro-4-methylphenyl}-3-methyl-2-thiophenecarboxamide
  • SMR000227755
  • ZINC01002167

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Leishmania mexicana pyruvate kinase, putative Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, putative 498 aa 515 aa 27.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0251
Brugia malayi Heterochromatin protein 1 0.0068 0.0363 0.047
Brugia malayi Melatonin receptor type 1A 0.0052 0.0258 0.0334
Echinococcus granulosus brain tumor protein 0.0031 0.0118 0.0117
Plasmodium vivax plasmepsin V, putative 0.0098 0.0562 0.1879
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0102 0.0584 0.0757
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0251 0.0324
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0102 0.0584 0.196
Schistosoma mansoni hypothetical protein 0.018 0.1101 0.1336
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.0584 0.2516
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0092 0.0287
Trypanosoma brucei unspecified product 0.0019 0.0039 0.0103
Brugia malayi fibroinase precursor 0.0102 0.0584 0.0757
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0138 0.0823 0.1066
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0634 0.2211
Trypanosoma cruzi cysteine peptidase, putative 0.0581 0.3741 0.6383
Echinococcus multilocularis hypothetical protein 0.0041 0.0183 0.0183
Leishmania major cathepsin L-like protease 0.0442 0.2825 0.7527
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0109 0.0345
Entamoeba histolytica cysteine proteinase, putative 0.0239 0.1493 0.5219
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1183 0.771 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0258 0.0258
Toxoplasma gondii aspartyl protease ASP3 0.0098 0.0562 0.1879
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0899 0.584 1
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Schistosoma mansoni chromobox protein 0.0068 0.0363 0.044
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0419 0.0418
Echinococcus multilocularis cathepsin L 0.0102 0.0584 0.0583
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0103
Schistosoma mansoni hypothetical protein 0.0049 0.0238 0.0289
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0399 0.0484
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0103 0.1096
Loa Loa (eye worm) calpain family protein 1 0.0108 0.0628 0.0813
Schistosoma mansoni survival motor neuron protein 0.0058 0.0298 0.0361
Giardia lamblia DINP protein human, muc B family 0.0019 0.0039 0.0004
Schistosoma mansoni Mername-AA248 (C02 family) 0.0041 0.0183 0.0222
Loa Loa (eye worm) B-box zinc finger family protein 0.0031 0.0119 0.0153
Trypanosoma brucei kinesin, putative 0.0029 0.0103 0.0274
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0249 0.0757
Schistosoma mansoni neuropeptide receptor 0.0052 0.0258 0.0313
Brugia malayi cathepsin F-like cysteine proteinase 0.0138 0.0823 0.1066
Schistosoma mansoni amine GPCR 0.0052 0.0258 0.0313
Mycobacterium ulcerans pyruvate kinase 0.004 0.018 0.2384
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0102 0.0584 0.196
Trypanosoma cruzi kinesin, putative 0.0029 0.0103 0.0112
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1183 0.771 0.771
Echinococcus granulosus orexin receptor type 2 0.0052 0.0258 0.0258
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0133
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0442 0.2825 1
Echinococcus granulosus cathepsin L 0.0239 0.1493 0.1492
Giardia lamblia Cathepsin B precursor 0.0102 0.0584 0.2516
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0249 0.0364
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0258 0.0258
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0183 0.0251
Brugia malayi cathepsin Z-like cysteine proteinase 0.0102 0.0584 0.0757
Giardia lamblia Hypothetical protein 0.0063 0.033 0.1347
Leishmania major DNA polymerase eta, putative 0.0019 0.0039 0.0002
Entamoeba histolytica calpain large subunit domain III containing protein 0.0029 0.0103 0.0233
Schistosoma mansoni amine GPCR 0.0052 0.0258 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.033 0.1132
Trypanosoma brucei antigen, putative 0.0041 0.0183 0.049
Leishmania major cathepsin L-like protease 0.0442 0.2825 0.7527
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0258 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0304 0.1917 0.6771
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0258 0.0334
Plasmodium falciparum cysteine proteinase falcipain 1 0.0239 0.1493 0.5219
Mycobacterium tuberculosis Conserved protein 0.0036 0.0154 0.0825
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Brugia malayi beta-lactamase 0.0036 0.0154 0.0198
Schistosoma mansoni chromobox protein 0.0068 0.0363 0.044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0822 0.0998
Echinococcus granulosus sex peptide receptor 0.0052 0.0258 0.0258
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0258 0.0736
Echinococcus granulosus chromobox protein 1 0.0068 0.0363 0.0362
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0415 0.2652 0.2652
Brugia malayi Papain family cysteine protease containing protein 0.0442 0.2825 0.3664
Onchocerca volvulus 0.0052 0.0258 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.0584 0.0709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0822 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.1493 0.5264
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.071 0.0862
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0128
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1797 0.1796
Giardia lamblia Cathepsin B precursor 0.0102 0.0584 0.2516
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0363 0.047
Echinococcus granulosus calpain A 0.0041 0.0183 0.0183
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0085 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Trypanosoma cruzi cysteine proteinase, putative 0.0239 0.1493 0.2508
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Onchocerca volvulus 0.0098 0.0562 0.1829
Schistosoma mansoni hypothetical protein 0.0058 0.0298 0.0361
Onchocerca volvulus Matrilysin homolog 0.0047 0.0226 0.0617
Loa Loa (eye worm) NCL-1 protein 0.0031 0.0118 0.0152
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0055 0.0063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.0584 0.2034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0102 0.0584 0.196
Brugia malayi Hemopexin family protein 0.003 0.0113 0.0146
Giardia lamblia Cathepsin L-like protease 0.0102 0.0584 0.2516
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0419 0.0507
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0183 0.049
Brugia malayi G-protein coupled receptor 0.0052 0.0258 0.0334
Schistosoma mansoni amine GPCR 0.0052 0.0258 0.0313
Brugia malayi Cathepsin L-like cysteine proteinase 0.0304 0.1917 0.2485
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0229 0.1427 0.1732
Trypanosoma cruzi cruzipain precursor, putative 0.0581 0.3741 0.6383
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0154 0.0825
Onchocerca volvulus Cathepsin L homolog 0.0442 0.2825 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0258 0.0258
Onchocerca volvulus 0.0052 0.0258 0.0736
Plasmodium falciparum plasmepsin VI 0.0415 0.2652 0.9379
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0113 0.066 0.0659
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0698 0.0697
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0415 0.2652 0.3221
Entamoeba histolytica prefoldin subunit 6, putative 0.0063 0.033 0.105
Loa Loa (eye worm) hypothetical protein 0.0138 0.0823 0.1066
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.033 0.0504
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0258 0.0258
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0102 0.0584 0.196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Echinococcus granulosus pyruvate kinase 0.0021 0.0051 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0102 0.0584 0.0709
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0258 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0039 0.0095
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0185 0.047
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0096 0.0547 0.0708
Trichomonas vaginalis esterase, putative 0.0036 0.0154 0.0504
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0109 0.0255
Plasmodium vivax plasmepsin IV, putative 0.0415 0.2652 0.9379
Echinococcus multilocularis protein dispatched 1 0.0058 0.0298 0.0297
Toxoplasma gondii aspartyl protease 0.0098 0.0562 0.1879
Echinococcus multilocularis serotonin receptor 0.0052 0.0258 0.0258
Schistosoma mansoni hypothetical protein 0.0052 0.0258 0.0313
Trypanosoma cruzi cysteine proteinase, putative 0.0239 0.1493 0.2508
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.0584 0.0709
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0634 0.161
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.1096
Brugia malayi Pepsin A precursor 0.0098 0.0562 0.0727
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.0584 0.0709
Brugia malayi cathepsin F-like cysteine proteinase 0.0102 0.0584 0.0757
Schistosoma mansoni adenoreceptor 0.0052 0.0258 0.0313
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0092
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0183 0.0222
Schistosoma mansoni hypothetical protein 0.0049 0.0238 0.0289
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0102 0.0584 0.196
Echinococcus multilocularis sex peptide receptor 0.0052 0.0258 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0098 0.0562 0.1879
Echinococcus granulosus cpg binding protein 0.0037 0.0156 0.0155
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0039 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0239 0.1493 0.5219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Plasmodium vivax aspartyl proteinase, putative 0.0098 0.0562 0.1879
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0109 0.0255
Plasmodium falciparum plasmepsin VII 0.0098 0.0562 0.1879
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0183 0.0251
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0304 0.1917 0.2485
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0258 0.0313
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0108 0.0628 0.0762
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Schistosoma mansoni dopamine-beta-monooxygenase 0.0628 0.4055 0.4924
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0183 0.0251
Echinococcus granulosus cathepsin l cysteine peptidase 0.0442 0.2825 0.2825
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0038 0.0037
Onchocerca volvulus 0.0442 0.2825 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0103 0.0322
Echinococcus multilocularis chromobox protein 1 0.0068 0.0363 0.0362
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0249 0.0665
Schistosoma mansoni hypothetical protein 0.0043 0.0201 0.0243
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.004 0.0099
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0109 0.0255
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0823 0.1353
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.2825 0.2825
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Plasmodium falciparum serine repeat antigen 6 0.0102 0.0584 0.196
Echinococcus multilocularis brain tumor protein 0.0031 0.0118 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Brugia malayi MH2 domain containing protein 0.012 0.0708 0.0917
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0102 0.0584 0.196
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0419 0.0542
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0185 0.0615
Echinococcus granulosus pyruvate kinase 0.004 0.018 0.0179
Brugia malayi Pyruvate kinase, muscle isozyme 0.004 0.018 0.0232
Echinococcus granulosus tripartite motif containing protein 3 0.0031 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Probable conserved membrane protein 0.0031 0.0118 0.0572
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS18 0.0031 0.0118 0.0572
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0102 0.0584 0.2516
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0016 0.0013
Echinococcus granulosus expressed conserved protein 0.0112 0.065 0.065
Entamoeba histolytica cysteine proteinase, putative 0.0239 0.1493 0.5219
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0138 0.0823 0.1066
Onchocerca volvulus 0.0052 0.0258 0.0736
Plasmodium vivax aspartyl protease, putative 0.0098 0.0562 0.1879
Plasmodium vivax serine-repeat antigen (SERA) 0.0102 0.0584 0.196
Echinococcus multilocularis chromobox protein 1 0.0068 0.0363 0.0362
Schistosoma mansoni histamine h1 receptor 0.0052 0.0258 0.0313
Plasmodium vivax aspartyl protease, putative 0.0098 0.0562 0.1879
Schistosoma mansoni hypothetical protein 0.0031 0.0118 0.0142
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0258 0.0258
Mycobacterium ulcerans hydrolase 0.0026 0.0085 0.0799
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0698 0.0697
Loa Loa (eye worm) hypothetical protein 0.006 0.0308 0.0398
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0249 0.0757
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0309 0.1954 0.2533
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0183 0.049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0822 0.0822
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0258 0.0258
Leishmania major hypothetical protein, conserved 0.0051 0.0249 0.057
Brugia malayi sulfakinin receptor protein 0.0679 0.4391 0.5694
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0154 0.0186
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0077 0.0425 0.0424
Schistosoma mansoni neuropeptide receptor 0.0052 0.0258 0.0313
Onchocerca volvulus 0.0098 0.0562 0.1829
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.007
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0415 0.2652 0.9384
Echinococcus granulosus tumor protein p63 0.0408 0.2604 0.2603
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0154 0.0825
Toxoplasma gondii cathepsin CPC1 0.0102 0.0584 0.196
Plasmodium falciparum cysteine proteinase falcipain 3 0.0442 0.2825 1
Brugia malayi phosphofructokinase 0.0109 0.0634 0.0821
Schistosoma mansoni hypothetical protein 0.0049 0.0238 0.0289
Loa Loa (eye worm) B-box zinc finger family protein 0.0031 0.0118 0.0152
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0419 0.0507
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0154 0.0198
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Giardia lamblia Cathepsin B precursor 0.0102 0.0584 0.2516
Onchocerca volvulus 0.003 0.0113 0.0212
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0348 0.221 0.3743
Loa Loa (eye worm) aspartyl protease 6 0.0098 0.0562 0.0727
Echinococcus granulosus calpain 5 0.0041 0.0183 0.0183
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.004 0.018 0.1012
Brugia malayi Serotonin receptor 0.0052 0.0258 0.0334
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Echinococcus granulosus neuropeptide s receptor 0.0052 0.0258 0.0258
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.6369 0.6369
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0183 0.0222
Schistosoma mansoni hypothetical protein 0.0031 0.0118 0.0142
Giardia lamblia Cathepsin L-like protease 0.0102 0.0584 0.2516
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.1034 0.1034
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Loa Loa (eye worm) RING finger protein nhl-1 0.0031 0.0118 0.0152
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0038 0.0037
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0258 0.0313
Brugia malayi B-box type zinc-finger protein ncl-1 0.0031 0.0118 0.0152
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0039 0.0002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0258 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0348 0.221 0.7812
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0103 0.0465
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0258 0.0313
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0258 0.0334
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0415 0.2652 0.3439
Leishmania major pyruvate kinase 0.004 0.018 0.0384
Echinococcus granulosus tar DNA binding protein 0.0076 0.0419 0.0418
Trypanosoma cruzi cysteine protease, putative 0.0239 0.1493 0.2508
Onchocerca volvulus 0.0052 0.0258 0.0736
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0319 0.2015 0.2613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Entamoeba histolytica hypothetical protein 0.0102 0.0584 0.196
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0258 0.0313
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0154 0.0153
Brugia malayi GnHR receptor homolog 0.0052 0.0258 0.0334
Entamoeba histolytica pyruvate kinase, putative 0.0028 0.0099 0.0222
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0258 0.0313
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0258 0.0258
Trypanosoma brucei pyruvate kinase 1, putative 0.004 0.018 0.0481
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0109 0.0255
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0634 0.0633
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi Dopamine receptor protein 1 0.0052 0.0258 0.0334
Echinococcus multilocularis pyruvate kinase 0.004 0.018 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.0584 0.2034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.0584 0.2034
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0039 0.0103
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0634 0.2139
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0249 0.0757
Brugia malayi beta-lactamase family protein 0.0036 0.0154 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0154 0.0504
Schistosoma mansoni biogenic amine receptor 0.0052 0.0258 0.0313
Brugia malayi hypothetical protein 0.0098 0.0562 0.0727
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0258 0.0258
Echinococcus granulosus dna polymerase kappa 0.0019 0.0039 0.0038
Echinococcus granulosus g protein coupled receptor 0.0052 0.0258 0.0258
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.0584 0.2034
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0154 0.0825
Echinococcus granulosus g protein coupled receptor 0.0052 0.0258 0.0258
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.066 0.0801
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1262 0.8233 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.033 0.0504
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0176
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0176
Plasmodium falciparum plasmepsin IX 0.0098 0.0562 0.1879
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0251 0.0849
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0133
Giardia lamblia Pyruvate kinase 0.0021 0.0051 0.006
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0822 0.1066
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0899 0.584 0.7093
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0258 0.0334
Leishmania major prefoldin subunit, putative 0.0063 0.033 0.079
Onchocerca volvulus 0.0035 0.0143 0.0318
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0183 0.0251
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.066 0.0801
Onchocerca volvulus 0.0052 0.0258 0.0736
Brugia malayi RE15519p 0.0052 0.0258 0.0334
Brugia malayi RNA binding protein 0.0076 0.0419 0.0542
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.0152
Leishmania major pyruvate kinase 0.004 0.018 0.0384
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.0152
Onchocerca volvulus 0.0442 0.2825 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0154 0.0186
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0103 0.0176
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0258 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0102 0.0584 0.196
Loa Loa (eye worm) hypothetical protein 0.0138 0.0823 0.1066
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.018 0.0452
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0154 0.0504
Mycobacterium ulcerans hypothetical protein 0.0036 0.0154 0.1944
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.2825 0.2825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Plasmodium vivax vivapain-2 0.0442 0.2825 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0039 0.0049
Entamoeba histolytica cysteine proteinase, putative 0.0239 0.1493 0.5219
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0708 0.0917
Echinococcus multilocularis protein patched 0.0051 0.0251 0.025
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0251 0.025
Trypanosoma cruzi cysteine peptidase, putative 0.0442 0.2825 0.4804
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0166 0.0401
Echinococcus granulosus cathepsin b 0.0899 0.584 0.584
Onchocerca volvulus 0.003 0.0111 0.0205
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0258 0.0334
Echinococcus granulosus cathepsin L cysteine proteinase 0.0442 0.2825 0.2825
Onchocerca volvulus 0.0304 0.1917 0.6721
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Plasmodium vivax vivapain-1 0.0239 0.1493 0.5219
Loa Loa (eye worm) hypothetical protein 0.0062 0.0326 0.0422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.1493 0.5264
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Plasmodium vivax aspartyl proteinase, putative 0.0415 0.2652 0.9379
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.0584 0.0709
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Echinococcus multilocularis tachykinin peptides receptor 99D 0.153 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0102 0.0584 0.2034
Onchocerca volvulus 0.0052 0.0258 0.0736
Plasmodium falciparum plasmepsin X 0.0098 0.0562 0.1879
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Plasmodium falciparum prefoldin subunit 6, putative 0.0063 0.033 0.105
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0251 0.025
Giardia lamblia Cathepsin B precursor 0.0102 0.0584 0.2516
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) ctsf protein 0.0442 0.2825 0.3664
Brugia malayi KE2 family protein 0.0063 0.033 0.0427
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0064 0.0064
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0258 0.0313
Brugia malayi Cathepsin L-like precursor 0.0138 0.0823 0.1066
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0109 0.0255
Brugia malayi Matrixin family protein 0.0021 0.0055 0.007
Brugia malayi cathepsin Z-like cysteine proteinase 0.0102 0.0584 0.0757
Brugia malayi hypothetical protein 0.0033 0.013 0.0168
Plasmodium falciparum plasmepsin I 0.0415 0.2652 0.9379
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0109 0.429
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0419 0.0507
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0103
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0258 0.0313
Loa Loa (eye worm) hypothetical protein 0.0138 0.0823 0.1066
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0634 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0049
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Loa Loa (eye worm) hypothetical protein 0.0063 0.033 0.0427
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0251 0.025
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0133
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0258 0.0313
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0634 0.1028
Entamoeba histolytica hypothetical protein 0.0043 0.0201 0.0585
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0258 0.0258
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0628 0.4055 0.5259
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0258 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0016 0.0013
Echinococcus multilocularis pyruvate kinase 0.0021 0.0051 0.005
Schistosoma mansoni opsin-like receptor 0.0052 0.0258 0.0313
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.018 0.0245
Echinococcus multilocularis neuropeptide receptor A26 0.0052 0.0258 0.0258
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0102 0.0584 0.0757
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0822 0.0998
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0258 0.0334
Leishmania major kinesin, putative 0.0029 0.0103 0.0175
Entamoeba histolytica cysteine protease, putative 0.0442 0.2825 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0258 0.0313
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0103 0.0234
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0899 0.584 0.7093
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0049
Mycobacterium leprae Probable lipase LipE 0.0036 0.0154 0.1244
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0183 0.049
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0109 0.429
Brugia malayi G protein-coupled receptor 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0304 0.1917 0.2485
Toxoplasma gondii ABC1 family protein 0.0036 0.0154 0.0416
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0055 0.0066
Leishmania major DNA polymerase kappa, putative 0.0019 0.0039 0.0002
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0442 0.2825 1
Echinococcus multilocularis tumor protein p63 0.0408 0.2604 0.2603
Plasmodium vivax pyruvate kinase, putative 0.004 0.018 0.051
Leishmania major cathepsin L-like protease 0.0442 0.2825 0.7527
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0102 0.0584 0.196
Plasmodium falciparum pyruvate kinase 0.004 0.018 0.051
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0584 0.2034
Mycobacterium tuberculosis Conserved protein 0.0036 0.0154 0.0825
Onchocerca volvulus Cathepsin L homolog 0.0102 0.0584 0.1911
Echinococcus granulosus calpain 7 C02 family 0.0041 0.0183 0.0183
Brugia malayi Pyruvate kinase, M2 isozyme 0.004 0.018 0.0232
Brugia malayi cathepsin B-like cysteine proteinase 0.0899 0.584 0.7575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.0584 0.0757
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0102 0.0584 0.196
Onchocerca volvulus 0.0442 0.2825 1
Leishmania major cathepsin L-like protease 0.0581 0.3741 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni DNA polymerase eta 0.0019 0.0039 0.0046
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0258 0.0258
Trypanosoma cruzi major cysteine proteinase, putative 0.0241 0.15 0.252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Toxoplasma gondii cathepsin B 0.0348 0.221 0.7791
Loa Loa (eye worm) hypothetical protein 0.0051 0.0249 0.0322
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0154 0.0825
Brugia malayi Papain family cysteine protease containing protein 0.0239 0.1493 0.1935
Plasmodium falciparum serine repeat antigen 1 0.0102 0.0584 0.196
Plasmodium falciparum pyruvate kinase 2 0.0021 0.0051 0.0046
Brugia malayi cathepsin L-like precursor 0.0304 0.1917 0.2485
Schistosoma mansoni hypothetical protein 0.0052 0.0258 0.0313
Schistosoma mansoni cpg binding protein 0.0035 0.0143 0.0173
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0055 0.0296
Schistosoma mansoni cathepsin s 0.0138 0.0823 0.0999
Entamoeba histolytica protein kinase, putative 0.0029 0.0103 0.0233
Onchocerca volvulus 0.0052 0.0258 0.0736
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0258 0.0258
Entamoeba histolytica hypothetical protein 0.0043 0.0201 0.0585
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.2825 0.2825
Plasmodium vivax serine-repeat antigen (SERA) 0.0102 0.0584 0.196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Onchocerca volvulus 0.0052 0.0258 0.0736
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0154 0.0153
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0249 0.0364
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0899 0.584 0.7093
Loa Loa (eye worm) hypothetical protein 0.0679 0.4391 0.5694
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0258 0.0258
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Echinococcus multilocularis calpain 0.0041 0.0183 0.0183
Toxoplasma gondii cathepsin CPL 0.0442 0.2825 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0092
Loa Loa (eye worm) pyruvate kinase 0.004 0.018 0.0232
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Schistosoma mansoni pyruvate kinase 0.004 0.018 0.0217
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0258 0.0313
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0031 0.0118 0.0315
Brugia malayi CHE-14 protein 0.0051 0.0251 0.0324
Echinococcus granulosus dnaJ subfamily B 0.0494 0.317 0.317
Echinococcus granulosus neuropeptide receptor A26 0.0052 0.0258 0.0258
Schistosoma mansoni neuropeptide receptor 0.0052 0.0258 0.0313
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0363 0.1248
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0039 0.0038
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0258 0.0258
Trypanosoma brucei cysteine peptidase C (CPC) 0.0348 0.221 0.5906
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0039 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Plasmodium falciparum plasmepsin VIII, putative 0.0098 0.0562 0.1879
Schistosoma mansoni hypothetical protein 0.003 0.0113 0.0137
Onchocerca volvulus 0.0029 0.0103 0.0174
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0258 0.0258
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0038
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0185 0.0615
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0258 0.0313
Loa Loa (eye worm) hypothetical protein 0.1183 0.771 1
Echinococcus granulosus pyruvate kinase 0.0021 0.0051 0.005
Loa Loa (eye worm) calpain family protein 1 0.008 0.044 0.0569
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1183 0.771 0.9364
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0308 0.0373
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0258 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Brugia malayi aspartic protease BmAsp-2, identical 0.0098 0.0562 0.0727
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0258 0.0334
Giardia lamblia Pyruvate kinase 0.004 0.018 0.0655
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Echinococcus multilocularis cysteine protease 0.0442 0.2825 0.2825
Leishmania major cathepsin L-like protease 0.0442 0.2825 0.7527
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0258 0.0258
Leishmania major cysteine peptidase A (CPA) 0.0442 0.2825 0.7527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0634 0.0821
Schistosoma mansoni brat protein 0.0031 0.0118 0.0142
Schistosoma mansoni microtubule-associated protein tau 0.0733 0.4746 0.5764
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Schistosoma mansoni amine GPCR 0.0052 0.0258 0.0313
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0258 0.0334
Giardia lamblia Cysteine protease 0.0102 0.0584 0.2516
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Brugia malayi larval opioid receptor 0.0052 0.0258 0.0334
Echinococcus multilocularis pyruvate kinase 0.0032 0.0124 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0109 0.0255
Loa Loa (eye worm) hypothetical protein 0.0067 0.0359 0.0464
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0258 0.0313
Onchocerca volvulus 0.0058 0.0298 0.0879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Brugia malayi chromobox protein homolog 3 0.0038 0.0166 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Giardia lamblia Haloacid dehalogenase-like hydrolase family 0.0031 0.0118 0.037
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0634 1
Echinococcus granulosus allatostatin A receptor 0.0052 0.0258 0.0258
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0634 0.2139
Onchocerca volvulus 0.0052 0.0258 0.0736
Onchocerca volvulus 0.0052 0.0258 0.0736
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0038 0.0101
Brugia malayi G-protein coupled receptor 0.0052 0.0258 0.0334
Echinococcus multilocularis prefoldin subunit 6 0.0063 0.033 0.0329
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0348 0.221 0.2683
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0102 0.0584 0.0709
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0394
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0258 0.0258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0154 0.02
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0419 0.0507
Schistosoma mansoni cathepsin C 0.0102 0.0584 0.0709
Brugia malayi Cathepsin L-like precursor 0.0442 0.2825 0.3664
Brugia malayi Matrixin family protein 0.0021 0.0055 0.007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.1096
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.018 0.0452
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0258 0.0258
Echinococcus granulosus cysteine protease 0.0239 0.1493 0.1492
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Plasmodium falciparum plasmepsin III 0.0098 0.0562 0.1879
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0144
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0286 0.1797 0.2329
Brugia malayi calpain family protein 1 0.0108 0.0628 0.0813
Brugia malayi AKH receptor 0.0052 0.0258 0.0334
Leishmania major cathepsin L-like protease 0.0442 0.2825 0.7527
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0258 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Echinococcus multilocularis cysteine protease 0.0442 0.2825 0.2825
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0103 0.1096
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0415 0.2652 0.2652
Echinococcus granulosus somatostatin receptor 0.0052 0.0258 0.0258
Schistosoma mansoni cpg binding protein 0.0037 0.0156 0.0188
Brugia malayi Dopamine receptor protein 2 0.0052 0.0258 0.0334
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0258 0.0258
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0415 0.2652 0.9379
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0103 0.0322
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0251
Schistosoma mansoni opsin-like receptor 0.0052 0.0258 0.0313
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0258 0.0258
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS17 0.0031 0.0118 0.0572
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0214
Onchocerca volvulus 0.0067 0.0359 0.1097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0071
Toxoplasma gondii prefoldin subunit 6, putative 0.0063 0.033 0.105
Onchocerca volvulus 0.0102 0.0584 0.1911
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0258 0.0736
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0822 0.0822
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0038
Echinococcus granulosus dna polymerase eta 0.0019 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Echinococcus granulosus serotonin receptor 0.0052 0.0258 0.0258
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0239 0.1493 0.1812
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Echinococcus multilocularis cathepsin b 0.0899 0.584 0.584
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0249 0.0757
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0071
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0258 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.0584 0.2034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0039 0.0007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0239 0.1493 0.1812
Brugia malayi Papain family cysteine protease containing protein 0.0239 0.1493 0.1935
Loa Loa (eye worm) pyruvate kinase 0.004 0.018 0.0232
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0103 0.0465
Schistosoma mansoni hypothetical protein 0.0052 0.0258 0.0313
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.0584 0.2516
Echinococcus multilocularis cathepsin b 0.0899 0.584 0.584
Plasmodium falciparum plasmepsin V 0.0098 0.0562 0.1879
Mycobacterium ulcerans beta-lactamase 0.0036 0.0154 0.1944
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0039 0.0095
Plasmodium falciparum plasmepsin II 0.0415 0.2652 0.9379
Brugia malayi Serotonin receptor 0.0052 0.0258 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0102 0.0584 0.2034
Echinococcus granulosus cathepsin L cysteine protease 0.0239 0.1493 0.1492
Brugia malayi CXXC zinc finger family protein 0.0035 0.0143 0.0184
Mycobacterium tuberculosis Conserved protein 0.0036 0.0154 0.0825
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0258 0.0258
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0258 0.0258
Schistosoma mansoni myosin xvIII 0.0052 0.0258 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0239 0.1493 0.399
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0085 0.011
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0258 0.0258
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0258 0.0258
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0258 0.0334
Echinococcus granulosus neuropeptide receptor 0.0052 0.0258 0.0258
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0102 0.0584 0.196
Schistosoma mansoni hypothetical protein 0.0023 0.0064 0.0077
Entamoeba histolytica cysteine proteinase 2 0.0239 0.1493 0.5219
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0154 0.0825
Echinococcus multilocularis cpg binding protein 0.0037 0.0156 0.0155
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0634 0.0821
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0201 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.007
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.018 0.0245
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Schistosoma mansoni calpain C (C02 family) 0.0041 0.0183 0.0222
Brugia malayi 6-phosphofructokinase 0.0109 0.0634 0.0821
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0002
Plasmodium falciparum serine repeat antigen 2 0.0102 0.0584 0.196
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0103 0.1096
Schistosoma mansoni peptidylglycine monooxygenase 0.0031 0.0118 0.0142
Loa Loa (eye worm) beta-lactamase 0.0036 0.0154 0.0198
Loa Loa (eye worm) hypothetical protein 0.0628 0.4055 0.5259
Echinococcus granulosus cathepsin l1 0.0304 0.1917 0.1916
Onchocerca volvulus 0.0052 0.0258 0.0736
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Entamoeba histolytica cysteine proteinase, putative 0.0304 0.1917 0.6741
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0363 0.1248
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0103
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.2825 0.2825
Schistosoma mansoni neuropeptide receptor 0.0052 0.0258 0.0313
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0258 0.0313
Schistosoma mansoni cathepsin S (C01 family) 0.0102 0.0584 0.0709
Brugia malayi Hypothetical RING finger protein F54G8.4 in chromosome III 0.0031 0.0118 0.0152
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0031 0.0118 0.0315
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0822 0.1066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Brugia malayi B-box zinc finger family protein 0.0031 0.0118 0.0152
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0258 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0584 0.2034
Giardia lamblia Hypothetical protein 0.0102 0.0584 0.2516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.0584 0.2034
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0154 0.0504
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0258 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.2825 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0038 0.5
Schistosoma mansoni pyruvate kinase 0.004 0.018 0.0217
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0048 0.0071
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0154 0.1244
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.0584 0.0709
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Onchocerca volvulus 0.0442 0.2825 1
Loa Loa (eye worm) cathepsin B 0.0348 0.221 0.2865
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0098 0.0562 0.0727
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0258 0.0258
Onchocerca volvulus 0.0036 0.0154 0.0357
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0183 0.049
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0039 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0102 0.0584 0.2034
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0443 0.2833 0.4817
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0634 0.0633
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0258 0.0334
Onchocerca volvulus Cathepsin F homolog 0.0442 0.2825 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) calpain 0.0041 0.0183 0.0237
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0102 0.0584 0.196
Plasmodium vivax unspecified product 0.0138 0.0823 0.2817
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0347 0.1111
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0102 0.0584 0.196
Schistosoma mansoni biogenic amine receptor 0.0052 0.0258 0.0313
Echinococcus granulosus pyruvate kinase 0.0021 0.0051 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0166 0.0548
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.317 0.317
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0258 0.0334
Onchocerca volvulus 0.0052 0.0258 0.0736
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Plasmodium falciparum serine repeat antigen 3 0.0102 0.0584 0.196
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0039 0.0046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0048 0.0071
Brugia malayi aspartic protease BmAsp-1, identical 0.0098 0.0562 0.0727
Giardia lamblia Hypothetical protein 0.0031 0.0118 0.037
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0419 0.0507
Plasmodium vivax unspecified product 0.0239 0.1493 0.5219
Onchocerca volvulus 0.0036 0.0154 0.0357
Schistosoma mansoni cathepsin F (C01 family) 0.0304 0.1917 0.2327
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0102 0.0584 0.0757
Loa Loa (eye worm) hypothetical protein 0.0098 0.0562 0.0727
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0708 0.0917
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.018 0.0597
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.2825 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0092 0.0287
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0634 0.0769
Onchocerca volvulus 0.0052 0.0258 0.0736
Echinococcus multilocularis tripartite motif containing protein 3 0.0031 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.004 0.018 0.0232
Echinococcus multilocularis dna polymerase eta 0.0019 0.0039 0.0038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0103 0.1096
Brugia malayi TAR-binding protein 0.0076 0.0419 0.0542
Leishmania major cathepsin L-like protease 0.0581 0.3741 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.0152
Schistosoma mansoni hypothetical protein 0.0031 0.0118 0.0142
Giardia lamblia Cathepsin B precursor 0.0348 0.221 1
Mycobacterium leprae Probable pyruvate kinase PykA 0.004 0.018 0.1722
Brugia malayi 6-phosphofructokinase 0.0109 0.0634 0.0821
Loa Loa (eye worm) matrixin family protein 0.0052 0.0254 0.0328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0239 0.1493 0.399
Echinococcus multilocularis somatostatin receptor 0.0052 0.0258 0.0258
Schistosoma mansoni hypothetical protein 0.0031 0.0118 0.0142
Echinococcus multilocularis expressed conserved protein 0.0112 0.065 0.065
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0041 0.0183 0.0251
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0102 0.0584 0.0757
Schistosoma mansoni cathepsin B (C01 family) 0.0102 0.0584 0.0709
Toxoplasma gondii aspartyl protease ASP1 0.0415 0.2652 0.9379
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) pyruvate kinase-PB 0.0028 0.0099 0.0128
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Plasmodium falciparum serine repeat antigen 9 0.0102 0.0584 0.196
Loa Loa (eye worm) matrixin family protein 0.0047 0.0226 0.0292
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0055 0.007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Schistosoma mansoni cpg binding protein 0.0037 0.0156 0.0188
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0077 0.0425 0.0424
Echinococcus multilocularis serotonin receptor 0.0052 0.0258 0.0258
Onchocerca volvulus 0.0036 0.0154 0.0357
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0201 0.02
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0634 0.2211
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0016
Mycobacterium ulcerans hypothetical protein 0.0029 0.0103 0.1096
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0038 0.0048
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0698 0.0904
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0154 0.0504
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0109 0.0255
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0258 0.0313
Loa Loa (eye worm) hypothetical protein 0.0899 0.584 0.7575
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0258 0.0258
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Loa Loa (eye worm) cysteine protease 0.0442 0.2825 0.3664
Entamoeba histolytica hypothetical protein 0.0031 0.0118 0.0288
Echinococcus granulosus pyruvate kinase 0.004 0.018 0.0179
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0258 0.0258
Toxoplasma gondii pyruvate kinase PyK1 0.004 0.018 0.051
Entamoeba histolytica cysteine proteinase 1, putative 0.0239 0.1493 0.5219
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0102 0.0584 0.196
Echinococcus granulosus calpain A 0.0113 0.066 0.0659
Brugia malayi cathepsin L precursor 0.0102 0.0584 0.0757
Echinococcus multilocularis pyruvate kinase 0.0021 0.0051 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0394
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0102 0.0584 0.0757
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0258 0.0313
Echinococcus granulosus fmrfamide receptor 0.0052 0.0258 0.0258
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0258 0.0258
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0258 0.0313
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0154 0.0825
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Plasmodium vivax calpain, putative 0.0041 0.0183 0.0523
Echinococcus multilocularis geminin 0.018 0.1101 0.11
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0258 0.0313
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Brugia malayi B-box type zinc-finger protein ncl-1 0.0031 0.0118 0.0152
Schistosoma mansoni calpain (C02 family) 0.0041 0.0183 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0154 0.0198
Schistosoma mansoni hypothetical protein 0.0052 0.0258 0.0313
Plasmodium falciparum serine repeat antigen 8 0.0102 0.0584 0.196
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0154 0.0416
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0634 0.2211
Plasmodium vivax unspecified product 0.0102 0.0584 0.196
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Onchocerca volvulus Cathepsin L homolog 0.0442 0.2825 1
Plasmodium vivax pyruvate kinase 2, putative 0.0021 0.0051 0.0046
Loa Loa (eye worm) fibroinase 0.0442 0.2825 0.3664
Schistosoma mansoni hypothetical protein 0.0049 0.0238 0.0289
Leishmania major cathepsin L-like protease 0.0581 0.3741 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0102 0.0584 0.196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Schistosoma mansoni hypothetical protein 0.0063 0.033 0.04
Echinococcus granulosus prefoldin subunit 6 0.0063 0.033 0.0329
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.1443 1
Giardia lamblia Encystation-specific protease 0.0102 0.0584 0.2516
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Echinococcus multilocularis brain tumor protein 0.0031 0.0118 0.0117
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0183 0.0251
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0258 0.0334
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0154 0.1944
Entamoeba histolytica hypothetical protein 0.0043 0.0201 0.0585
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0634 0.2139
Schistosoma mansoni hypothetical protein 0.0494 0.317 0.385
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Brugia malayi Eukaryotic aspartyl protease family protein 0.0098 0.0562 0.0727
Plasmodium vivax vivapain-2 0.0442 0.2825 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi calpain 7 0.0041 0.0183 0.0237
Echinococcus granulosus geminin 0.018 0.1101 0.11
Giardia lamblia Hypothetical protein 0.0102 0.0584 0.2516
Trypanosoma cruzi cysteine peptidase, putative 0.0239 0.1493 0.2508
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Plasmodium falciparum serine repeat antigen 4 0.0102 0.0584 0.196
Brugia malayi hypothetical protein 0.0098 0.0562 0.0727
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0634 0.1694
Echinococcus granulosus cathepsin b 0.0899 0.584 0.584
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0442 0.2825 0.3664
Trypanosoma cruzi cysteine peptidase, putative 0.0581 0.3741 0.6383
Echinococcus multilocularis neuropeptide s receptor 0.0052 0.0258 0.0258
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0899 0.584 0.7093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0258 0.0313
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0039 0.0003
Giardia lamblia Cysteine protease 0.0102 0.0584 0.2516
Toxoplasma gondii preprocathepsin c precursor, putative 0.0102 0.0584 0.196
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0038 0.0048
Loa Loa (eye worm) hypothetical protein 0.0108 0.0628 0.0813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0304 0.1917 0.6771
Loa Loa (eye worm) RNA binding protein 0.0076 0.0419 0.0542
Brugia malayi neuropeptide F receptor 0.0052 0.0258 0.0334
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0239 0.1493 0.2508
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0041 0.0183 0.049
Giardia lamblia Cathepsin B precursor 0.0348 0.221 1
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.0584 0.0757
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0258 0.0334
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0419 0.0542
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni cathepsin D (A01 family) 0.1085 0.7063 0.8579
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.007
Chlamydia trachomatis pyruvate kinase 0.004 0.018 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0258 0.0313
Echinococcus multilocularis pyruvate kinase 0.004 0.018 0.0179
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0258 0.0313
Onchocerca volvulus 0.0442 0.2825 1
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0226 0.0617
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0103
Brugia malayi calpain family protein 1 0.0108 0.0628 0.0813
Plasmodium falciparum serine repeat antigen 7 0.0102 0.0584 0.196
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0822 0.0822
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.0584 0.2034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0581 0.3741 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0442 0.2825 0.3664
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0258 0.0313
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0103 0.0234
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0239 0.1493 0.1812
Echinococcus granulosus cathepsin l1 0.0442 0.2825 0.2825
Trypanosoma brucei pyruvate kinase 1 0.004 0.018 0.0481
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Trypanosoma cruzi cysteine peptidase, putative 0.0581 0.3741 0.6383
Schistosoma mansoni amine GPCR 0.0052 0.0258 0.0313
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0698 0.2369
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0201 0.02
Leishmania major hypothetical protein, conserved 0.0036 0.0154 0.0313
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0634 0.2211
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0109 0.0255
Echinococcus multilocularis microtubule associated protein 2 0.0733 0.4746 0.4746
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0102 0.0584 0.196
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0348 0.221 0.5865
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0109 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0102 0.0584 0.2034
Entamoeba histolytica hypothetical protein 0.0043 0.0201 0.0585
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0166 0.0548
Echinococcus granulosus calpain 0.0041 0.0183 0.0183
Echinococcus multilocularis cathepsin L 0.0239 0.1493 0.1492
Brugia malayi B-box zinc finger family protein 0.0031 0.0119 0.0153
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0258 0.0258
Brugia malayi Matrixin family protein 0.0021 0.0055 0.007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0143 0.0184
Loa Loa (eye worm) calpain 5 0.0029 0.0103 0.0132
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0394
Schistosoma mansoni hypothetical protein 0.018 0.1101 0.1336
Schistosoma mansoni cathepsin D (A01 family) 0.1085 0.7063 0.8579
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0258 0.0258
Toxoplasma gondii cathepsin CPC2 0.0102 0.0584 0.196
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0098 0.0562 0.0727
Giardia lamblia Cysteine protease 0.0102 0.0584 0.2516
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0258 0.0334
Echinococcus granulosus chromobox protein 1 0.0068 0.0363 0.0362
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0154 0.0825
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0113 0.066 0.0659
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1183 0.771 0.771
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0154 0.0504
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0251
Loa Loa (eye worm) pyruvate kinase 0.004 0.018 0.0232
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0016
Onchocerca volvulus 0.0052 0.0258 0.0736
Loa Loa (eye worm) hypothetical protein 0.0415 0.2652 0.3439
Brugia malayi ORL1-like opioid receptor 0.0052 0.0258 0.0334
Schistosoma mansoni biogenic amine receptor 0.0052 0.0258 0.0313
Loa Loa (eye worm) hypothetical protein 0.008 0.044 0.0569
Brugia malayi Matrixin family protein 0.0021 0.0055 0.007
Toxoplasma gondii pyruvate kinase PyKII 0.0021 0.0051 0.0046
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0064 0.0064
Brugia malayi neuropeptide F receptor 0.0052 0.0258 0.0334
Brugia malayi Cathepsin L-like precursor 0.0304 0.1917 0.2485
Brugia malayi calpain 5 0.0029 0.0103 0.0132
Loa Loa (eye worm) hypothetical protein 0.0304 0.1917 0.2485
Brugia malayi putative neuropeptide receptor 0.0052 0.0258 0.0334
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.0584 0.2516
Schistosoma mansoni patched 1 0.0051 0.0251 0.0303
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.2825 0.3431
Entamoeba histolytica cysteine protease, putative 0.0102 0.0584 0.196
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0634 0.0769
Echinococcus granulosus cathepsin L 0.0102 0.0584 0.0583
Echinococcus granulosus microtubule associated protein 2 0.0733 0.4746 0.4746
Echinococcus multilocularis calpain 5 0.0041 0.0183 0.0183
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.2825 0.3431
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0154 0.041
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0258 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0048 0.0071
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Trypanosoma cruzi major cysteine proteinase, putative 0.0102 0.0584 0.0942
Loa Loa (eye worm) hypothetical protein 0.0119 0.0698 0.0904
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0154 0.1944
Onchocerca volvulus 0.0442 0.2825 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0103 0.0234
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0258 0.0258
Plasmodium vivax vivapain-3 0.0239 0.1493 0.5219
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0822 0.0998
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0103 0.1096
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Echinococcus granulosus hypothetical protein 0.0052 0.0258 0.0258
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.0584 0.0757
Onchocerca volvulus 0.0442 0.2825 1
Trypanosoma cruzi kinesin, putative 0.0029 0.0103 0.0112
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0258 0.0334
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0345
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0055 0.0126
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0634 0.4243
Echinococcus granulosus neuropeptide receptor 0.0052 0.0258 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.2825 1
Schistosoma mansoni pyruvate kinase 0.0021 0.0051 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0258 0.0258
Brugia malayi hypothetical protein 0.0286 0.1797 0.2329
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.2825 1
Brugia malayi hypothetical protein 0.0043 0.0201 0.0259
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0258 0.0258
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0258 0.0334
Brugia malayi hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0298 0.0386
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Loa Loa (eye worm) hypothetical protein 0.0036 0.0154 0.0198
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0634 0.0821
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0634 1
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0258 0.0258
Brugia malayi Matrixin family protein 0.0052 0.0254 0.0328
Brugia malayi Dopamine receptor 0.0052 0.0258 0.0334
Giardia lamblia Cathepsin B precursor 0.0348 0.221 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0258 0.0258
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0258 0.0258
Schistosoma mansoni peptidylglycine monooxygenase 0.0628 0.4055 0.4924
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0055 0.0063
Echinococcus multilocularis calpain A 0.0113 0.066 0.0659
Giardia lamblia Cysteine protease 0.0102 0.0584 0.2516
Brugia malayi hypothetical protein 0.0051 0.0249 0.0322
Onchocerca volvulus 0.0052 0.0258 0.0736
Onchocerca volvulus 0.0052 0.0258 0.0736
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0098 0.0562 0.0681
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.0002
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0258 0.0258
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0102 0.0584 0.0709
Plasmodium vivax prefoldin subunit 6, putative 0.0063 0.033 0.105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.004 0.0099
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0183 0.0251
Echinococcus multilocularis calpain 7 (C02 family) 0.0041 0.0183 0.0183
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0823 0.1353
Echinococcus granulosus g protein coupled receptor 0.0052 0.0258 0.0258
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0419 0.0542
Brugia malayi Cathepsin L-like precursor 0.0304 0.1917 0.2485
Giardia lamblia Cathepsin L precursor 0.0102 0.0584 0.2516
Entamoeba histolytica cysteine protease, putative 0.0239 0.1493 0.5219
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0109 0.1192
Plasmodium falciparum plasmepsin IV 0.0415 0.2652 0.9379
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0103 0.0133
Trypanosoma brucei prefoldin subunit, putative 0.0063 0.033 0.0883
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0133
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.018 0.0597
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.004 0.0099
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.1034 0.1034
Schistosoma mansoni memapsin-2 (A01 family) 0.0098 0.0562 0.0681
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0334
Brugia malayi beta-lactamase family protein 0.0036 0.0154 0.0198
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0102 0.0584 0.0709
Plasmodium vivax aspartyl protease, putative 0.0098 0.0562 0.1879
Onchocerca volvulus 0.0052 0.0258 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0258 0.0258
Giardia lamblia Cathepsin B precursor 0.0102 0.0584 0.2516
Onchocerca volvulus 0.006 0.0308 0.0914
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.0584 0.2034
Echinococcus multilocularis pyruvate kinase 0.0021 0.0051 0.005
Plasmodium falciparum serine repeat antigen 5 0.0102 0.0584 0.196
Loa Loa (eye worm) hypothetical protein 0.0442 0.2825 0.3664
Echinococcus multilocularis calpain family protein 1, d 0.008 0.044 0.0439
Brugia malayi hypothetical protein 0.0679 0.4391 0.5694
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1797 0.1796
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0258 0.0258
Mycobacterium ulcerans lipase LipD 0.0036 0.0154 0.1944
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0071
Brugia malayi cathepsin L-like cysteine proteinase 0.0102 0.0584 0.0757
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0048 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0251 0.0324
Schistosoma mansoni opsin-like receptor 0.0052 0.0258 0.0313
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.018 0.0452

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.6511 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.2213 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.3582 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 11.5821 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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