Detailed information for compound 1537759

Basic information

Technical information
  • TDR Targets ID: 1537759
  • Name: methyl 3,4,5-trihydroxycyclohexane-1-carboxyl ate
  • MW: 190.194 | Formula: C8H14O5
  • H donors: 3 H acceptors: 4 LogP: -1.28 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1CC(O)C(C(C1)O)O
  • InChi: 1S/C8H14O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h4-7,9-11H,2-3H2,1H3
  • InChiKey: BHBGXBOEMPWGLO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3,4,5-trihydroxy-1-cyclohexanecarboxylic acid methyl ester
  • 3,4,5-trihydroxycyclohexane-1-carboxylic acid methyl ester
  • NCIOpen2_000125
  • NSC62511

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0007 0.003 0.0046
Schistosoma mansoni smad1 5 8 and 0.0008 0.0045 0.0079
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0622 0.1342
Brugia malayi Cytochrome P450 family protein 0.0007 0.002 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0622 0.5092
Echinococcus granulosus single minded 2 0.0071 0.1363 0.1363
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0327 0.0327
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0399 1
Schistosoma mansoni glucose transport protein 0.0208 0.4209 0.7315
Loa Loa (eye worm) hypothetical protein 0.0009 0.0063 0.0095
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0622 0.1276
Schistosoma mansoni amine GPCR 0.0025 0.0402 0.0698
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0874 0.0874
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0198 0.4013 0.6072
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0364 0.9126
Brugia malayi Pre-SET motif family protein 0.003 0.0507 0.0767
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Plasmodium vivax CDK-related protein kinase 6, putative 0.0443 0.9132 1
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.1363 0.1363
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0045 0.0045
Toxoplasma gondii ABC1 family protein 0.0036 0.0622 0.103
Schistosoma mansoni opsin-like receptor 0.0025 0.0402 0.0698
Brugia malayi Latrophilin receptor protein 2 0.0063 0.1186 0.1794
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.1221 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0364 0.0551
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0199 0.1628
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi AKH receptor 0.0025 0.0402 0.0607
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Leishmania major cytochrome p450-like protein 0.0007 0.002 0.0164
Loa Loa (eye worm) hypoxia-induced factor 1 0.0298 0.6089 0.9211
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Echinococcus multilocularis General substrate transporter 0.0178 0.36 0.36
Onchocerca volvulus 0.0025 0.0402 0.0766
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0402 0.0402
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0402 0.0402
Echinococcus granulosus peptide allatostatin:somatostatin 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0015 0.0183 0.0277
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0844 0.0844
Onchocerca volvulus 0.0046 0.0844 0.168
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Brugia malayi sulfakinin receptor protein 0.0025 0.0402 0.0607
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0118 0.0964
Schistosoma mansoni amine GPCR 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus granulosus g protein coupled receptor 0.0025 0.0402 0.0402
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.1186 0.1794
Echinococcus granulosus g protein coupled receptor 0.0025 0.0402 0.0402
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Loa Loa (eye worm) hypothetical protein 0.0032 0.0545 0.0824
Brugia malayi mbt repeat family protein 0.0046 0.0844 0.1277
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.003 0.0046
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0545 0.0903
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Echinococcus granulosus serotonin receptor 0.0025 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Onchocerca volvulus 0.0025 0.0402 0.0766
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0531 0.9752
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.064 0.5241
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0025 0.0402 0.0607
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0223 0.0337
Schistosoma mansoni thyroid hormone receptor 0.0007 0.003 0.0052
Onchocerca volvulus 0.0036 0.0622 0.1221
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0223 0.0244
Loa Loa (eye worm) sugar transporter 0.0029 0.0486 0.0736
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0007 0.002 0.0043
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0486 0.357
Brugia malayi Steroid receptor seven-up type 2 0.0007 0.003 0.0046
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0063 0.1186
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.4633 1
Echinococcus multilocularis serotonin receptor 0.0025 0.0402 0.0402
Onchocerca volvulus 0.0025 0.0402 0.0766
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0399 0.3267
Onchocerca volvulus 0.0029 0.0486 0.0942
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0007 0.002 0.0043
Onchocerca volvulus 0.0025 0.0402 0.0766
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.4266 0.6453
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0911 0.7464
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.2152 0.8945
Onchocerca volvulus 0.0029 0.0486 0.0942
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Schistosoma mansoni protein kinase 0.0032 0.0545 0.0947
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0484 0.0484
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.1884 0.3274
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Leishmania major glucose transporter, lmgt3 0.0064 0.1221 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0118 0.0964
Schistosoma mansoni glucose transport protein 0.0208 0.4209 0.7315
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0223 0.0457
Schistosoma mansoni sugar transporter 0.0029 0.0486 0.0845
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0364 0.0399
Echinococcus multilocularis somatostatin receptor 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0622 0.1342
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0025 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.0063 0.1186 0.2061
Trichomonas vaginalis set domain proteins, putative 0.0239 0.4872 1
Giardia lamblia Hypothetical protein 0.0009 0.0058 0.1097
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.2345 0.3548
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0441 0.3609
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0007 0.002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0007 0.003 0.003
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0007 0.002 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0007 0.002 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0402 0.0698
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0007 0.003 0.0052
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Brugia malayi ORL1-like opioid receptor 0.0025 0.0402 0.0607
Echinococcus granulosus solute carrier family 22 0.0029 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0009 0.0058 0.0088
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0007 0.002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Schistosoma mansoni single-minded 0.0096 0.1884 0.3274
Toxoplasma gondii sugar transporter ST2 0.0029 0.0486 0.0806
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0037 0.0644 0.0644
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Brugia malayi hypothetical protein 0.0029 0.0486 0.0736
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0199 0.0301
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0223 0.1825
Brugia malayi hypothetical protein 0.0029 0.0486 0.0736
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.002 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0622 0.1276
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0911 0.1509
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0.002 0.0164
Echinococcus granulosus alpha 1A adrenergic receptor 0.0025 0.0402 0.0402
Brugia malayi G protein-coupled receptor 0.0025 0.0402 0.0607
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0622 0.1342
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0007 0.003 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Onchocerca volvulus 0.0025 0.0402 0.0766
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Treponema pallidum NADH oxidase 0.0017 0.0223 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Echinococcus multilocularis Smad4 0.0008 0.0045 0.0045
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0399 0.0819
Loa Loa (eye worm) glutathione reductase 0.0048 0.0874 0.1323
Brugia malayi MH1 domain containing protein 0.0008 0.0045 0.0069
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.2405 0.5192
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0025 0.0402 0.0402
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0486 0.3985
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0507 0.0881
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0364 0.2982
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0007 0.002 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0402 0.0402
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0545 0.0597
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.2152 0.4644
Trichomonas vaginalis sugar transporter, putative 0.0064 0.1221 0.2506
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0545 0.4464
Schistosoma mansoni biogenic amine receptor 0.0025 0.0402 0.0698
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0007 0.002 0.0147
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0622 0.4562
Echinococcus multilocularis solute carrier family 22 0.0029 0.0486 0.0486
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.064 0.5241
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0402 0.0698
Brugia malayi Tachykinin-like peptides receptor 99D 0.0025 0.0402 0.0607
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0402 0.0402
Onchocerca volvulus 0.0025 0.0399 0.0761
Schistosoma mansoni coup transcription factor 0.0007 0.003 0.0052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0007 0.003 0.0052
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0025 0.0402 0.0607
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0844 0.1467
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0402 0.0698
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0545 0.0597
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0364 0.2982
Loa Loa (eye worm) hypothetical protein 0.003 0.0507 0.0767
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0223 0.0244
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0007 0.003 0.003
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0874 0.0957
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0063 0.0095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0223 0.0223
Echinococcus multilocularis dro:myosuppressin receptor 0.0025 0.0402 0.0402
Schistosoma mansoni Smad4 0.0008 0.0045 0.0079
Trypanosoma cruzi hexose transporter, putative 0.0064 0.1221 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0118 0.0964
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0118 0.216
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0007 0.003 0.0052
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0007 0.002 0.0147
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Onchocerca volvulus 0.0036 0.0622 0.1221
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0327 0.0672
Echinococcus granulosus hypothetical protein 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0135 0.2705 0.4092
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0622 0.1276
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0233 0.0404
Schistosoma mansoni hypothetical protein 0.0007 0.002 0.0035
Brugia malayi MH2 domain containing protein 0.0008 0.0045 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Leishmania major protein kinase, putative 0.0027 0.0441 0.3609
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Echinococcus granulosus g-protein coupled receptor 0.0025 0.0402 0.0402
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0025 0.0402 0.0698
Mycobacterium ulcerans hydrolase 0.0009 0.0058 0.0428
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.002 0.0083
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0399 0.0819
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.2345 0.3548
Trypanosoma brucei trypanothione reductase 0.0048 0.0874 0.7162
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0364 0.2671
Brugia malayi major facilitator superfamily protein 0.0029 0.0486 0.0736
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.1221 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0198 0.4013 0.6072
Brugia malayi hypothetical protein 0.0009 0.0058 0.0088
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0486 0.0999
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0911 0.0998
Brugia malayi Cam kinase protein 1 0.0032 0.0545 0.0824
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0486 0.357
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0199 0.1628
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0486 0.0999
Leishmania major glucose transporter/membrane transporter D2, putative 0.0064 0.1221 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0291 0.0627
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.018 0.0273
Brugia malayi beta-lactamase 0.0036 0.0622 0.094
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0007 0.002 0.0147
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0223 0.1635
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0007 0.003 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0007 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0053 0.0978 0.1479
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0402 0.0402
Leishmania major cytochrome p450-like protein 0.0007 0.002 0.0164
Trypanosoma cruzi hexose transporter, putative 0.0064 0.1221 1
Brugia malayi nuclear receptor NHR-88 0.0007 0.003 0.0046
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0545 0.0824
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0399 0.0399
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0063 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0007 0.003 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0.002 0.0164
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0486 0.3985
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.4209 0.864
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0025 0.0402 0.0607
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Brugia malayi hypothetical protein 0.0032 0.0545 0.0824
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Loa Loa (eye worm) cytochrome P450 0.0007 0.002 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0007 0.002 0.0043
Onchocerca volvulus 0.0025 0.0402 0.0766
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0978 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.1221 0.2506
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.018 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0874 0.1887
Loa Loa (eye worm) steroid hormone receptor 0.0007 0.003 0.0046
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0399 0.0819
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.1186 0.1186
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0007 0.003 0.003
Brugia malayi nuclear hormone receptor 0.0007 0.003 0.0046
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Schistosoma mansoni smad 0.0008 0.0045 0.0079
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0007 0.002 0.0147
Brugia malayi major facilitator superfamily protein 0.0029 0.0486 0.0736
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0108 0.4865
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0402 0.0402
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0486 0.0736
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Plasmodium falciparum mitogen-activated protein kinase 2 0.0169 0.3401 0.3724
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0364 0.0633
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Onchocerca volvulus 0.0025 0.0402 0.0766
Brugia malayi Cytochrome P450 family protein 0.0007 0.002 0.003
Onchocerca volvulus 0.0029 0.0486 0.0942
Brugia malayi RE15519p 0.0025 0.0402 0.0607
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0223 0.0387
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0007 0.002 0.0043
Brugia malayi hypoxia-induced factor 1 0.0298 0.6089 0.9211
Schistosoma mansoni hypothetical protein 0.0282 0.5754 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0399 0.3267
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Onchocerca volvulus Netrin receptor homolog 0.0015 0.018 0.031
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0118 0.0242
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0223 0.1825
Schistosoma mansoni biogenic amine receptor 0.0025 0.0402 0.0698
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0223 0.1635
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0978 0.0978
Schistosoma mansoni glucose transport protein 0.0208 0.4209 0.7315
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Brugia malayi Dopamine receptor 0.0025 0.0402 0.0607
Echinococcus granulosus allatostatin A receptor 0.0025 0.0402 0.0402
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0007 0.002 0.0147
Mycobacterium ulcerans beta-lactamase 0.0036 0.0622 0.4562
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0025 0.0402 0.0402
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0441 0.3609
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0507 0.0881
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0025 0.0402 0.0698
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0545 0.0597
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0199 0.0345
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0507 0.0839
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0323 0.661 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0486 0.105
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0025 0.0402 0.0607
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0486 0.0999
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0025 0.0402 0.0607
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0007 0.002 0.0043
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0531 0.221
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0108 0.0795
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0545 0.0824
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0486 0.0486
Brugia malayi Pre-SET motif family protein 0.021 0.4266 0.6453
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0199 0.0199
Echinococcus granulosus solute carrier family 22 0.0029 0.0486 0.0486
Plasmodium falciparum hexose transporter 0.0208 0.4209 0.461
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0223 0.0481
Plasmodium falciparum glutathione reductase 0.0048 0.0874 0.0957
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0025 0.0402 0.0698
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0199 0.0199
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0545 0.0597
Echinococcus multilocularis ecdysone induced protein 78C 0.0007 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0545 0.0903
Mycobacterium ulcerans lipase LipD 0.0036 0.0622 0.4562
Brugia malayi larval opioid receptor 0.0025 0.0402 0.0607
Schistosoma mansoni neuropeptide receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0178 0.0295
Onchocerca volvulus 0.0029 0.0486 0.0942
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.064 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi MH2 domain containing protein 0.0008 0.0045 0.0069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0402 0.0698
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0063 0.0095
Echinococcus granulosus neuropeptide receptor 0.0025 0.0402 0.0402
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0007 0.002 0.0043
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0007 0.002 0.0147
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0486 0.3985
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0025 0.0402 0.0698
Echinococcus granulosus neuropeptide receptor A26 0.0485 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0025 0.0402 0.0607
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0545 0.0903
Plasmodium falciparum thioredoxin reductase 0.0048 0.0874 0.0957
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.143 0.143
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0364 0.1513
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0402 0.0402
Leishmania major protein kinase, putative 0.0032 0.0545 0.4464
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0402 0.0402
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0223 0.0369
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0364 0.0364
Echinococcus granulosus FTZ F1 alpha 0.0007 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Loa Loa (eye worm) hypothetical protein 0.005 0.0911 0.1379
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0364 0.0633
Giardia lamblia Hexose transporter 0.0029 0.0486 0.9153
Echinococcus granulosus GPCR family 2 0.0063 0.1186 0.1186
Echinococcus granulosus Ankyrin 0.0015 0.0183 0.0183
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0007 0.002 0.0147
Onchocerca volvulus 0.0029 0.0486 0.0942
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0978 0.1699
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.002 0.003
Trichomonas vaginalis glucose transporter, putative 0.0064 0.1221 0.2506
Schistosoma mansoni protein kinase 0.0032 0.0545 0.0947
Brugia malayi Uncoordinated protein 44 0.0015 0.018 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0486 0.0999
Schistosoma mansoni hypothetical protein 0.0022 0.0341 0.0593
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) hypothetical protein 0.0009 0.0058 0.0088
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.143 0.143
Schistosoma mansoni hypothetical protein 0.0208 0.4209 0.7315
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) hypothetical protein 0.032 0.6566 0.9934
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0007 0.003 0.0046
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0063 0.0069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Schistosoma mansoni DNA helicase recq5 0.0009 0.0063 0.011
Onchocerca volvulus 0.0025 0.0402 0.0766
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.018 0.018
Brugia malayi bHLH-PAS transcription factor 0.0071 0.1363 0.2061
Onchocerca volvulus 0.0029 0.0486 0.0942
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0622 0.108
Onchocerca volvulus 0.0025 0.0402 0.0766
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.1186 0.1794
Echinococcus multilocularis thyroid hormone receptor alpha 0.0007 0.003 0.003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0199 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0531 1
Onchocerca volvulus 0.0025 0.0402 0.0766
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0399 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0399 0.0819
Onchocerca volvulus 0.0029 0.0486 0.0942
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0399 0.0819
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0063 0.0104
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0025 0.0402 0.0607
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0486 0.0533
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0304 0.0624
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.064 0.5241
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0486 0.0999
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0402 0.0698
Echinococcus granulosus dro:myosuppressin receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.1186 0.1186
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0622 0.1342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0007 0.002 0.0043
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0486 0.357
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0058 0.0428
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.003 0.003
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.002 0.0164
Echinococcus granulosus sex peptide receptor 0.0025 0.0402 0.0402
Giardia lamblia Sugar-proton symporter 0.0029 0.0486 0.9153
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0844 0.1467
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Mycobacterium ulcerans sulfatase 0.0009 0.0058 0.0428
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Onchocerca volvulus 0.0029 0.0486 0.0942
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0007 0.002 0.0043
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0058 0.0428
Loa Loa (eye worm) beta-lactamase 0.0036 0.0622 0.094
Trypanosoma brucei glucose transporter 2A 0.0064 0.1221 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0402 0.0607
Onchocerca volvulus 0.0029 0.0486 0.0942
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.064 0.5241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Echinococcus granulosus neuropeptide receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0531 0.0531
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0291 0.0627
Brugia malayi Nuclear hormone receptor-like 1 0.0007 0.003 0.0046
Echinococcus granulosus fmrfamide receptor 0.0025 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.0025 0.0402 0.0698
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0007 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0036 0.0622 0.094
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.1186 0.1186
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0399 0.0399
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0007 0.002 0.0043
Mycobacterium tuberculosis Probable reductase 0.0109 0.2152 0.4644
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0399 0.0603
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0402 0.0402
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0223 0.1825
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0507 0.0507
Echinococcus granulosus g protein coupled receptor 0.0025 0.0402 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0007 0.003 0.0052
Brugia malayi Dopamine receptor protein 1 0.0025 0.0402 0.0607
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0399 0.0819
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0441 0.3609
Brugia malayi ecdysteroid receptor 0.0007 0.003 0.0046
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0199 0.0301
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0327 0.0672
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.2152 0.4644
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0199 0.0429
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0223 0.458
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0399 0.0399
Plasmodium vivax SET domain protein, putative 0.003 0.0507 0.0555
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0007 0.003 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0622 0.108
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0199 0.0329
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0622 0.1276
Echinococcus multilocularis Ankyrin 0.0015 0.0183 0.0183
Brugia malayi Thioredoxin reductase 0.0048 0.0874 0.1323
Schistosoma mansoni netrin receptor unc5 0.0015 0.018 0.0314
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.5041 0.7626
Schistosoma mansoni smad1 5 8 and 0.0008 0.0045 0.0079
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0911 0.0998
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.3687 0.3687
Schistosoma mansoni alpha-1 adrenergic receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0007 0.003 0.0046
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0486 0.3985
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0486 0.0845
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0223 0.0244
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0007 0.003 0.003
Brugia malayi neuropeptide F receptor 0.0025 0.0402 0.0607
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0486 0.0736
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Giardia lamblia Hypothetical protein 0.0009 0.0058 0.1097
Schistosoma mansoni smad1 5 8 and 0.0008 0.0045 0.0079
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Schistosoma mansoni neuropeptide receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Schistosoma mansoni protein kinase 0.0032 0.0545 0.0947
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.003 0.003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0045 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0007 0.003 0.0046
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0199 0.1628
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0223 0.0223
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.003 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.0025 0.0402 0.0402
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0364 0.2671
Toxoplasma gondii protein kinase, putative 0.0295 0.6038 1
Trichomonas vaginalis sugar transporter, putative 0.0064 0.1221 0.2506
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0622 0.1342
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0199 0.0329
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0182 0.0199
Mycobacterium leprae Possible regulatory protein 0.0025 0.0399 0.1658
Schistosoma mansoni hypothetical protein 0.0135 0.2705 0.47
Onchocerca volvulus 0.003 0.0507 0.0984
Echinococcus multilocularis neuropeptide receptor A26 0.0485 1 1
Onchocerca volvulus 0.0025 0.0402 0.0766
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.002 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0007 0.002 0.0147
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0507 0.0507
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0622 0.5092
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0341 0.0341
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0007 0.003 0.0046
Plasmodium falciparum proline--tRNA ligase 0.0037 0.064 0.0701
Onchocerca volvulus 0.0025 0.0402 0.0766
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0007 0.002 0.0147
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0622 0.2584
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0007 0.003 0.0046
Schistosoma mansoni hypothetical protein 0.0063 0.1186 0.2061
Brugia malayi beta-lactamase family protein 0.0036 0.0622 0.094
Mycobacterium tuberculosis Conserved protein 0.0036 0.0622 0.1342
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Echinococcus granulosus G protein coupled receptor 139 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0063 0.1186 0.1794
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0402 0.0698
Echinococcus multilocularis sodium channel protein 0.0037 0.0644 0.0644
Brugia malayi GnHR receptor homolog 0.0025 0.0402 0.0607
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Entamoeba histolytica protein kinase, putative 0.0032 0.0545 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.3687 0.3687
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus granulosus 7TM GPCR rhodopsin 0.0025 0.0402 0.0402
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0007 0.002 0.0147
Plasmodium vivax hexose transporter 0.0208 0.4209 0.461
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0622 0.094
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0622 0.4562
Trichomonas vaginalis esterase, putative 0.0036 0.0622 0.1276
Brugia malayi glutathione reductase 0.0048 0.0874 0.1323
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0486 0.0999
Brugia malayi beta-lactamase family protein 0.0036 0.0622 0.094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Brugia malayi Sugar transporter family protein 0.0029 0.0486 0.0736
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0025 0.0402 0.0402
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0007 0.003 0.003
Brugia malayi Serotonin receptor 0.0025 0.0402 0.0607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0025 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.0063 0.1186 0.2061
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0223 0.1825
Onchocerca volvulus 0.0029 0.0486 0.0942
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0007 0.002 0.0147
Mycobacterium tuberculosis Conserved protein 0.0036 0.0622 0.1342
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0844 0.0844
Schistosoma mansoni thyroid hormone receptor 0.0007 0.003 0.0052
Schistosoma mansoni hypothetical protein 0.0015 0.018 0.0314
Echinococcus multilocularis solute carrier family 22 0.0029 0.0486 0.0486
Trypanosoma cruzi hexose transporter, putative 0.0064 0.1221 1
Mycobacterium ulcerans putative regulatory protein 0.0071 0.1363 1
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0402 0.0698
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0545 0.0597
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.018 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Onchocerca volvulus 0.0025 0.0402 0.0766
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0531 0.0804
Echinococcus multilocularis serotonin receptor 0.0025 0.0402 0.0402
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0402 0.0402
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0025 0.0402 0.0402
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Schistosoma mansoni cytochrome P450 0.0007 0.002 0.0035
Loa Loa (eye worm) melatonin receptor type 1A 0.0025 0.0402 0.0607
Mycobacterium tuberculosis Probable sulfatase 0.0009 0.0058 0.0126
Brugia malayi G-protein coupled receptor 0.0025 0.0402 0.0607
Schistosoma mansoni steroid hormone receptor ad4bp 0.0007 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0531 0.0804
Onchocerca volvulus 0.0029 0.0486 0.0942
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.003 0.0046
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0911 0.0998
Mycobacterium leprae Probable lipase LipE 0.0036 0.0622 0.2584
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0045 0.0069
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0183 0.0318
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0223 0.0457
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0007 0.002 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Trypanosoma brucei glucose transporter 1E 0.0064 0.1221 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi hypothetical protein 0.0123 0.2444 0.3697
Brugia malayi G-protein coupled receptor 0.0025 0.0402 0.0607
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Plasmodium falciparum glutathione reductase 0.0017 0.0223 0.0244
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0025 0.0402 0.0698
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0223 0.1825
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0058 0.0126
Brugia malayi hypothetical protein 0.0323 0.661 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0486 0.0736
Echinococcus multilocularis 0.0007 0.002 0.002
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0058 0.0058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0622 0.1342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0131 0.0198
Echinococcus multilocularis neuropeptide s receptor 0.0485 1 1
Echinococcus multilocularis GPCR, family 2 0.0063 0.1186 0.1186
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0486 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.003 0.0046
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Schistosoma mansoni sugar transporter 0.0029 0.0486 0.0845
Schistosoma mansoni glucose transporter 0.0029 0.0486 0.0845
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Echinococcus multilocularis neuropeptide FF receptor 2 0.0025 0.0402 0.0402
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0545 0.1119
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0545 0.0597
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0622 0.094
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0978 0.1479
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.003 0.0046
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0531 0.0924
Onchocerca volvulus 0.0025 0.0402 0.0766
Schistosoma mansoni opsin-like receptor 0.0025 0.0402 0.0698
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0199 0.1628
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Toxoplasma gondii sugar transporter ST1 0.0029 0.0486 0.0806
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus multilocularis smad 0.0008 0.0045 0.0045
Toxoplasma gondii facilitative glucose transporter GT1 0.0208 0.4209 0.6972
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0007 0.002 0.0043
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0058 0.012
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0364 0.0399
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Leishmania major hypothetical protein, conserved 0.005 0.0911 0.7464
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0504 0.0504
Leishmania major trypanothione reductase 0.0048 0.0874 0.7162
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0364 0.0364
Brugia malayi Protein kinase domain containing protein 0.0017 0.0222 0.0336
Mycobacterium tuberculosis Conserved protein 0.0036 0.0622 0.1342
Loa Loa (eye worm) hypothetical protein 0.0025 0.0399 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0545 0.0947
Brugia malayi steroid hormone receptor 0.0007 0.003 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Echinococcus granulosus sodium channel protein 0.0037 0.0644 0.0644
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0545 0.0545
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0007 0.002 0.0147
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0223 0.1825
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0169 0.3401 0.3724
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.2152 0.4644
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0045 0.0045
Onchocerca volvulus 0.0025 0.0402 0.0766
Echinococcus multilocularis solute carrier family 22 0.0029 0.0486 0.0486
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0531 0.0531
Onchocerca volvulus 0.0029 0.0486 0.0942
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0622 0.5092
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0486 0.3985
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.2152 0.4644
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0399 0.0819
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0007 0.003 0.0046
Echinococcus multilocularis solute carrier family 22 0.0029 0.0486 0.0486
Echinococcus multilocularis sex peptide receptor 0.0025 0.0402 0.0402
Schistosoma mansoni opsin-like receptor 0.0025 0.0402 0.0698
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.2705 0.4092
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0622 0.0681
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0025 0.0402 0.0766
Schistosoma mansoni growth hormone secretagogue receptor 0.0025 0.0402 0.0698
Onchocerca volvulus 0.0025 0.0402 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.1221 0.2506
Schistosoma mansoni amine GPCR 0.0025 0.0402 0.0698
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0441 0.3609
Onchocerca volvulus 0.0029 0.0486 0.0942
Onchocerca volvulus 0.0071 0.1363 0.2751
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.2405 0.5192
Echinococcus granulosus Smad4 0.0008 0.0045 0.0045
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0007 0.003 0.0046
Brugia malayi hypothetical protein 0.0029 0.0486 0.0736
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi hypothetical protein 0.005 0.0911 0.1379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0025 0.0409 0.0618
Schistosoma mansoni hypothetical protein 0.0025 0.0402 0.0698
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0007 0.002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0486 0.0736
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0911 0.7464
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0844 0.0844
Schistosoma mansoni histamine h1 receptor 0.0025 0.0402 0.0698
Schistosoma mansoni neuropeptide receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0199 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0007 0.003 0.0046
Onchocerca volvulus Neuropeptide F receptor homolog 0.0025 0.0402 0.0766
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0223 0.0244
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0063 0.0063
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0531 0.1091
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0223 0.1825
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0844 0.1467
Brugia malayi follicle stimulating hormone receptor 0.0247 0.5041 0.7626
Echinococcus multilocularis FTZ F1 alpha 0.0007 0.003 0.003
Schistosoma mansoni adenoreceptor 0.0025 0.0402 0.0698
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0874 0.7162
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0063 0.0063
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0058 0.0428
Schistosoma mansoni nuclear hormone receptor 0.0007 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.002 0.0164
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0223 0.5586
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0007 0.003 0.003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0399 0.0819
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) Smad1 0.0008 0.0045 0.0069
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0063 0.0104
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Loa Loa (eye worm) TYRA-2 protein 0.0025 0.0402 0.0607
Echinococcus multilocularis G-protein coupled receptor, putative 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0291 0.1208
Brugia malayi Cytochrome P450 family protein 0.0007 0.002 0.003
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Echinococcus granulosus tachykinin peptides receptor 99D 0.0025 0.0402 0.0402
Entamoeba histolytica protein kinase, putative 0.0032 0.0545 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0223 0.1825
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0007 0.002 0.0147
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0364 0.6849
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0402 0.0698
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0058 0.0126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.003 0.0046
Echinococcus multilocularis allatostatin A receptor 0.0025 0.0402 0.0402
Echinococcus granulosus bloom syndrome protein 0.0022 0.0327 0.0327
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0486 0.0486
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Brugia malayi isocitrate dehydrogenase 0.0015 0.0199 0.0301
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.2405 1
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0504 0.0504
Schistosoma mansoni neuropeptide receptor 0.0025 0.0402 0.0698
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0007 0.003 0.0052
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0199 0.0199
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.1186 0.1186
Toxoplasma gondii sugar transporter ST3 0.0029 0.0486 0.0806
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0622 0.0622
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0507 0.0881
Schistosoma mansoni hypothetical protein 0.0063 0.1186 0.2061
Echinococcus granulosus neuropeptide FF receptor 2 0.0025 0.0402 0.0402
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0007 0.002 0.0147
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0531 0.0924
Schistosoma mansoni myosin xvIII 0.0025 0.0402 0.0698
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0399 0.0399
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0844 0.1277
Schistosoma mansoni biogenic amine receptor 0.0025 0.0402 0.0698
Trichomonas vaginalis glucose transporter, putative 0.0064 0.1221 0.2506
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0273 0.0299
Brugia malayi Serotonin receptor 0.0025 0.0402 0.0607
Leishmania major protein kinase, putative 0.0027 0.0441 0.3609
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0223 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0007 0.003 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0007 0.003 0.003
Brugia malayi Sugar transporter family protein 0.0029 0.0486 0.0736
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0402 0.0402
Echinococcus granulosus solute carrier family 22 0.0029 0.0486 0.0486
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.064 0.5241
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0199 0.0199
Trypanosoma brucei cytochrome P450, putative 0.0007 0.002 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0364 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Brugia malayi Death domain containing protein 0.0015 0.018 0.0273
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0402 0.0607
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.2152 0.4644
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0007 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0364 0.0551
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0545 0.0597
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0045 0.0045
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0486 0.105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0131 0.0198
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0025 0.0402 0.0402
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0622 0.0622
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0223 0.1635
Plasmodium falciparum protein kinase 7 0.0295 0.6038 0.6612
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0025 0.0402 0.0607
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0507 0.0881
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.1221 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0063 0.0063
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0486 1
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0874 0.1323
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0007 0.002 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0399 0.0819
Brugia malayi Dopamine receptor protein 2 0.0025 0.0402 0.0607
Schistosoma mansoni amine GPCR 0.0025 0.0402 0.0698
Entamoeba histolytica hypothetical protein 0.0023 0.0364 0.6679
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0978 0.0978
Brugia malayi mbt repeat family protein 0.0046 0.0844 0.1277
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0978 0.0978
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0402 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus multilocularis g-protein coupled receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0844 0.0844
Loa Loa (eye worm) CYP4Cod1 0.0007 0.002 0.003
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0169 0.3401 0.5632
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0874 0.0874
Schistosoma mansoni amine GPCR 0.0025 0.0402 0.0698
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0223 0.458
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0402 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0007 0.002 0.0043
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0063 0.0095
Trichomonas vaginalis sugar transporter, putative 0.0064 0.1221 0.2506
Brugia malayi putative neuropeptide receptor NPR1 0.0025 0.0402 0.0607
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0364 0.2982
Echinococcus granulosus solute carrier family 22 0.0029 0.0486 0.0486
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.2405 0.5192
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0045 0.0069
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Brugia malayi G protein-coupled receptor F59B2.13 0.0025 0.0402 0.0607
Schistosoma mansoni RAR-like nuclear receptor 0.0007 0.003 0.0052
Brugia malayi putative neuropeptide receptor 0.0025 0.0402 0.0607
Toxoplasma gondii thioredoxin reductase 0.0048 0.0874 0.1448
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0223 0.1825
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0622 0.1276
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Mycobacterium leprae putative cytochrome p450 0.0007 0.002 0.0083
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0402 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0007 0.003 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Echinococcus granulosus orexin receptor type 2 0.0025 0.0402 0.0402
Schistosoma mansoni sugar transporter 0.0029 0.0486 0.0845
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0199 0.1628
Echinococcus granulosus 7tm_1 domain containing protein 0.0025 0.0402 0.0402
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0223 0.4192
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0911 0.7464
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0025 0.0402 0.0698
Loa Loa (eye worm) hypothetical protein 0.0017 0.0236 0.0357
Onchocerca volvulus 0.0029 0.0486 0.0942
Brugia malayi neuropeptide F receptor 0.0025 0.0402 0.0607
Echinococcus granulosus netrin receptor unc 5 0.0015 0.018 0.018
Leishmania major hypothetical protein, conserved 0.0036 0.0622 0.5092
Onchocerca volvulus 0.0029 0.0486 0.0942
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.064 0.106
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0622 0.1342
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0007 0.002 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0025 0.0402 0.0402
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0399 0.0819
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0402 0.0607
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.002 0.003
Brugia malayi Smad1 0.0008 0.0045 0.0069
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0545 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0007 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.0736
Leishmania major glucose transporter, lmgt2 0.0064 0.1221 1
Onchocerca volvulus 0.0036 0.0622 0.1221
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Leishmania major glucose transporter, lmgt1 0.0064 0.1221 1
Onchocerca volvulus 0.0029 0.0486 0.0942
Echinococcus granulosus ecdysone induced protein 78C 0.0007 0.003 0.003
Echinococcus multilocularis orexin receptor type 2 0.0025 0.0402 0.0402
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0058 0.012
Mycobacterium ulcerans sugar transporter 0.0029 0.0486 0.357
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0198 0.4013 0.6072
Mycobacterium ulcerans hypothetical protein 0.0036 0.0622 0.4562
Brugia malayi cytochrome P450 0.0007 0.002 0.003
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0037 0.0644 0.5273
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.018 0.018
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.002 0.0164
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0007 0.002 0.0147
Echinococcus granulosus somatostatin receptor 0.0025 0.0402 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0486 0.0999
Schistosoma mansoni neuropeptide f receptor 76f 0.0025 0.0402 0.0698
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0108 0.2717
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0025 0.0402 0.0607
Trypanosoma cruzi hexose transporter 0.0064 0.1221 1
Echinococcus granulosus General substrate transporter 0.0178 0.36 0.36
Loa Loa (eye worm) hypothetical protein 0.0007 0.003 0.0046
Plasmodium vivax sugar transporter, putative 0.0029 0.0486 0.0533
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0146 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Brugia malayi MH1 domain containing protein 0.0008 0.0045 0.0069
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.4209 0.4209
Loa Loa (eye worm) hypothetical protein 0.0198 0.4013 0.6072
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0007 0.002 0.0147
Leishmania major cytochrome p450-like protein 0.0007 0.002 0.0164
Onchocerca volvulus 0.0239 0.4874 1
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0058 0.0428
Echinococcus granulosus death domain containing protein 0.0015 0.018 0.018
Trypanosoma brucei glucose transporter, putative 0.0064 0.1221 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0007 0.002 0.0043
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.0025 0.0402 0.0698
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0007 0.003 0.0052
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0402 0.0607
Trypanosoma brucei sugar transporter, putative 0.0029 0.0486 0.3985
Brugia malayi Sugar transporter family protein 0.0208 0.4209 0.6368
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0.002 0.0164
Brugia malayi PAS domain containing protein 0.0096 0.1884 0.285
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0025 0.0402 0.0698
Loa Loa (eye worm) RecQ helicase 0.0022 0.0327 0.0495
Mycobacterium tuberculosis Possible hydrolase 0.0009 0.0058 0.0126
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0531 0.0804
Loa Loa (eye worm) hypothetical protein 0.0015 0.018 0.0273
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0844 0.168
Schistosoma mansoni retinoic acid receptor RXR 0.0007 0.003 0.0052
Onchocerca volvulus 0.0025 0.0402 0.0766
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0402 0.0698
Leishmania major hypothetical protein, conserved 0.0029 0.0486 0.3985
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0402 0.0402
Loa Loa (eye worm) sugar transporter 0.0208 0.4209 0.6368
Plasmodium falciparum thioredoxin reductase 0.0017 0.0223 0.0244
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0223 0.1825
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0612 0.5011
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0208 0.4209 0.4209
Schistosoma mansoni sugar transporter 0.0029 0.0486 0.0845
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Schistosoma mansoni hypothetical protein 0.0025 0.0402 0.0698
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0545 0.0545
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0402 0.0402
Brugia malayi photoreceptor-specific nuclear receptor 0.0007 0.003 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0402 0.0402
Brugia malayi Cytochrome P450 family protein 0.0007 0.002 0.003
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0199 0.0218
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0486 0.0486
Echinococcus granulosus smad 0.0008 0.0045 0.0045
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0046 0.0844 0.1277
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0545 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0402 0.0402
Schistosoma mansoni DNA helicase recq1 0.0009 0.0063 0.011
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0327 0.0495
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0486 0.0806
Plasmodium falciparum protein kinase 6 0.0443 0.9132 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.018 0.0273
Loa Loa (eye worm) hypothetical protein 0.0031 0.0531 0.0804
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0007 0.002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0486 0.0999
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0364 0.0747
Brugia malayi hypothetical protein 0.0025 0.0402 0.0607
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0545 0.0597
Loa Loa (eye worm) MBCTL1 0.0053 0.0978 0.1479
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.0607
Brugia malayi MH2 domain containing protein 0.0118 0.2345 0.3548
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0486 0.0999
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0399 0.3267
Plasmodium vivax glutathione reductase, putative 0.0048 0.0874 0.0957
Brugia malayi Sulfatase family protein 0.0009 0.0058 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0507 0.0507
Brugia malayi Melatonin receptor type 1A 0.0025 0.0402 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0058 0.012
Onchocerca volvulus Putative transporter 0.0029 0.0486 0.0942

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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