Detailed information for compound 1568112

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 919.195 | Formula: C49H82N4O12
  • H donors: 6 H acceptors: 7 LogP: 4.56 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 3
  • SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(CCCNc2ccnc3c2cccc3)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O
  • InChi: 1S/C49H82N4O12/c1-14-38-49(10,59)42(55)32(6)53(12)27-28(2)25-47(8,58)44(30(4)41(31(5)45(57)63-38)64-39-26-48(9,60-13)43(56)33(7)62-39)65-46-40(54)37(24-29(3)61-46)52(11)23-17-21-50-36-20-22-51-35-19-16-15-18-34(35)36/h15-16,18-20,22,28-33,37-44,46,54-56,58-59H,14,17,21,23-27H2,1-13H3,(H,50,51)/t28-,29-,30+,31-,32-,33+,37+,38-,39+,40-,41+,42-,43+,44-,46+,47-,48-,49-/m1/s1
  • InChiKey: WGDLZZQEARLPRC-YFFKGRPLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Desert hedgehog protein 0.0212 0.2152 0.2514
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.003 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0164 0.1494
Schistosoma mansoni tar DNA-binding protein 0.007 0.0619 0.0662
Entamoeba histolytica hypothetical protein 0.0022 0.0095 0.0436
Echinococcus multilocularis dna polymerase eta 0.0023 0.0108 0.0084
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.021 0.022
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0099 0.0263
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.152 1
Echinococcus multilocularis tubulin alpha chain 0.0018 0.0061 0.0036
Echinococcus granulosus tubulin alpha chain 0.0018 0.0061 0.0043
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.0314 0.2063
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0099 0.0163
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0019 0.0072 0.01
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0099 0.0263
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0099 0.0463
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0164 0.1494
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.0475
Mycobacterium tuberculosis Mycolic acid synthase PcaA (cyclopropane synthase) 0.0041 0.0309 0.3746
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0019 0.0072 0.008
Schistosoma mansoni DNA helicase recq1 0.0022 0.0099 0.0046
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0068 0.0158
Trypanosoma brucei unspecified product 0.0023 0.0108 0.0116
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0042 0.0029
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0099 0.0103
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.003 0.0197
Onchocerca volvulus 0.0022 0.0095 0.0439
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0042 0.0099
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0164 0.0199
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0068 0.1459
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0095 0.0624
Echinococcus multilocularis Tubulin alpha 1 chain 0.0018 0.0061 0.0036
Brugia malayi intermediate filament protein 0.0031 0.0199 0.0398
Schistosoma mansoni lamin 0.0031 0.0199 0.0164
Brugia malayi Synaptic glycoprotein SC2 0.0022 0.0095 0.0153
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0309 0.0724
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0018 0.0061 0.0399
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0099 0.0103
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1509 0.2199
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0164 0.0165
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0108 0.0253
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0108 0.0057
Brugia malayi tubulin alpha-2 chain 0.0018 0.0061 0.0072
Echinococcus multilocularis muscleblind protein 0.0151 0.1497 0.1476
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0068 0.5
Trypanosoma brucei alpha tubulin 0.0018 0.0061 0.0045
Mycobacterium leprae POSSIBLE FATTY ACID SYNTHASE 0.0041 0.0309 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0484 0.1133
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0108 0.0057
Brugia malayi TAR-binding protein 0.007 0.0619 0.1388
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0444
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0164 0.1494
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0041 0.0309 0.3746
Loa Loa (eye worm) hypothetical protein 0.0311 0.3222 0.7543
Echinococcus granulosus lamin 0.0031 0.0199 0.0206
Trypanosoma brucei alpha tubulin 0.0018 0.0061 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.007
Echinococcus granulosus microtubule associated protein 2 0.0797 0.8489 1
Mycobacterium tuberculosis Possible mycolic acid synthase UmaA 0.0041 0.0309 0.3746
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0963 0.2255
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0164 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0072 0.0063
Trypanosoma brucei unspecified product 0.0016 0.0032 0.0003
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.0475
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0068 0.0056
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0019 0.0072 0.0169
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0043
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0108 0.0184
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0314 0.2063
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0057
Mycobacterium leprae MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE) 0.0041 0.0309 1
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0019 0.0072 0.0169
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0451
Echinococcus granulosus tubulin alpha chain 0.0018 0.0061 0.0043
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0314 0.2063
Leishmania major cytochrome p450-like protein 0.0028 0.0164 0.0199
Echinococcus multilocularis lamin dm0 0.0031 0.0199 0.0175
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0099 0.0163
Echinococcus multilocularis 0.0028 0.0164 0.014
Plasmodium falciparum geranylgeranyltransferase, putative 0.0019 0.0072 0.3032
Echinococcus granulosus synaptic glycoprotein sc2 0.0022 0.0095 0.0083
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0099 0.8065
Schistosoma mansoni hypothetical protein 0.0032 0.021 0.0178
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0164 0.0664
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0164 0.0664
Echinococcus multilocularis tubulin alpha chain 0.0018 0.0061 0.0036
Brugia malayi Latrophilin receptor protein 2 0.0032 0.021 0.0425
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0022 0.0095 0.0624
Schistosoma mansoni hypothetical protein 0.0383 0.4006 0.468
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0164 0.1494
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.0314 0.1734
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0019 0.0072 0.0057
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0022 0.0095 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0169
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0314 0.2063
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.152 0.2215
Schistosoma mansoni hypothetical protein 0.0032 0.021 0.0178
Trypanosoma brucei C-8 sterol isomerase, putative 0.0408 0.4272 0.6305
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0108 0.0084
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0019 0.0072 0.0475
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0332 0.3458 0.5095
Trypanosoma brucei alpha tubulin 0.0018 0.0061 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Leishmania major DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0019 0.0072 0.3032
Loa Loa (eye worm) RNA binding protein 0.007 0.0619 0.1449
Trypanosoma cruzi protein farnesyltransferase, putative 0.0019 0.0072 0.0063
Trypanosoma cruzi protein farnesyltransferase, putative 0.0019 0.0072 0.0063
Echinococcus multilocularis tubulin alpha 1C chain 0.0018 0.0061 0.0036
Schistosoma mansoni alpha-glucosidase 0.0162 0.1615 0.1844
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.021 0.0492
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0164 0.1494
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0164 0.0664
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0164 0.0384
Loa Loa (eye worm) hypothetical protein 0.0153 0.152 0.3559
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0314 0.2063
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0022 0.0095 0.0041
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0153 0.152 1
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0099 0.0651
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0351 0.0385
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.0314 0.029
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.0475
Entamoeba histolytica tubulin alpha-1 chain 0.0018 0.0061 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0164 0.1494
Plasmodium vivax polyprenol reductase, putative 0.0022 0.0095 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0164 0.1494
Loa Loa (eye worm) hypothetical protein 0.0031 0.0199 0.0465
Trypanosoma cruzi lanosterol synthase, putative 0.0142 0.14 0.2037
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0108 0.0099
Loa Loa (eye worm) hypothetical protein 0.0023 0.0108 0.0253
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0022 0.0095 0.0097
Schistosoma mansoni DNA polymerase eta 0.0023 0.0108 0.0057
Mycobacterium leprae CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC AC 0.0041 0.0309 1
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0108 0.0184
Schistosoma mansoni DNA helicase recq5 0.0022 0.0099 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0164 0.0664
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0351 0.0327
Loa Loa (eye worm) tubulin alpha 2 0.0014 0.0014 0.0033
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0314 0.1903
Loa Loa (eye worm) hypothetical protein 0.0408 0.4272 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.0314 0.0342
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.021 0.0186
Echinococcus multilocularis hypothetical protein 0.0018 0.0061 0.0036
Trypanosoma brucei lanosterol synthase 0.0142 0.14 0.2037
Brugia malayi Cytochrome P450 family protein 0.0028 0.0164 0.0316
Echinococcus multilocularis tar DNA binding protein 0.007 0.0619 0.0596
Echinococcus multilocularis tubulin alpha chain 0.0018 0.0061 0.0036
Schistosoma mansoni hypothetical protein 0.0028 0.0164 0.0123
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Echinococcus granulosus intermediate filament protein 0.0031 0.0199 0.0206
Loa Loa (eye worm) tubulin alpha-2 chain 0.0018 0.0061 0.0142
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0019 0.0072 0.0014
Echinococcus multilocularis Tubulin alpha 1 chain 0.0018 0.0061 0.0036
Echinococcus granulosus lamin dm0 0.0031 0.0199 0.0206
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0108 0.0116
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.2024
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0022 0.0095 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0444
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0019 0.0072 0.0283
Echinococcus granulosus muscleblind protein 0.0151 0.1497 0.174
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Echinococcus granulosus tubulin alpha 3 chain 0.0018 0.0061 0.0043
Leishmania major lanosterol synthase, putative 0.0123 0.119 0.1724
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0019 0.0072 0.0014
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Echinococcus granulosus tubulin alpha 1C chain 0.0018 0.0061 0.0043
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0164 0.0709
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Echinococcus multilocularis musashi 0.0031 0.0199 0.0175
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0142
Loa Loa (eye worm) hypothetical protein 0.0032 0.021 0.0492
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0314 0.2063
Trypanosoma brucei glucosidase, putative 0.0042 0.0314 0.0422
Brugia malayi Glycosyl hydrolases family 31 protein 0.0188 0.1899 0.4405
Leishmania major cytochrome p450-like protein 0.0028 0.0164 0.0199
Trypanosoma cruzi alpha tubulin, putative 0.0018 0.0061 0.0045
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0153 0.152 1
Giardia lamblia Rab geranylgeranyltransferase 0.0019 0.0072 0.2445
Echinococcus granulosus tubulin subunit TubB 0.0018 0.0061 0.0043
Echinococcus granulosus tubulin alpha 1C chain 0.0018 0.0061 0.0043
Trypanosoma brucei unspecified product 0.0016 0.0032 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0108 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Echinococcus granulosus dna polymerase kappa 0.0023 0.0108 0.0099
Schistosoma mansoni tar DNA-binding protein 0.007 0.0619 0.0662
Leishmania major geranylgeranyltransferase, putative 0.0019 0.0072 0.0063
Echinococcus multilocularis tubulin alpha chain 0.0018 0.0061 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0003
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0041 0.0309 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0164 0.0664
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.021 0.022
Schistosoma mansoni microtubule-associated protein tau 0.0797 0.8489 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0164 0.1494
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0164 0.0664
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Loa Loa (eye worm) transcription factor SMAD2 0.0138 0.1354 0.317
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0164 0.0199
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0164 0.0664
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0003
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0014 0.0014 0.0093
Trichomonas vaginalis tubulin epsilon chain, putative 0.0018 0.0061 0.0399
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.003 0.0197
Echinococcus multilocularis muscleblind protein 1 0.0151 0.1497 0.1476
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0164 0.0664
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0068 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0164 0.1494
Schistosoma mansoni intermediate filament proteins 0.0031 0.0199 0.0164
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0019 0.0072 0.3032
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0108 0.028
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.152 1
Brugia malayi MH2 domain containing protein 0.0138 0.1354 0.3122
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0153 0.152 0.2215
Leishmania major C-8 sterol isomerase-like protein 0.0408 0.4272 0.6305
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0164 0.0664
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0164 0.1494
Mycobacterium ulcerans hypothetical protein 0.0153 0.152 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0099 0.0232
Schistosoma mansoni hypothetical protein 0.0032 0.021 0.0178
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0164 0.0664
Echinococcus granulosus Tubulin alpha 1 chain 0.0018 0.0061 0.0043
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0079 0.0713 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0108 0.0116
Schistosoma mansoni tar DNA-binding protein 0.007 0.0619 0.0662
Echinococcus multilocularis tubulin alpha 1C chain 0.0018 0.0061 0.0036
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.008
Loa Loa (eye worm) tubulin alpha chain 0.0018 0.0061 0.0142
Mycobacterium ulcerans methoxy mycolic acid synthase 4, MmaA4 0.0041 0.0309 0.1665
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0099 0.0651
Mycobacterium ulcerans mycolic acid synthase PcaA 0.0041 0.0309 0.1665
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0314 0.2063
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.003 0.0197
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0019 0.0072 0.0283
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0099 0.0075
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0164 0.0199
Loa Loa (eye worm) alpha-tubulin 0.0018 0.0061 0.0142
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0188 0.1899 0.4445
Echinococcus granulosus geminin 0.0383 0.4006 0.4703
Giardia lamblia Prenyltransferase 0.0019 0.0072 0.2445
Mycobacterium ulcerans methoxy mycolic acid synthase 5 MmaA5 0.0041 0.0309 0.1665
Leishmania major cytochrome p450-like protein 0.0028 0.0164 0.0199
Schistosoma mansoni cytochrome P450 0.0028 0.0164 0.0123
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0068 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0095 0.0624
Brugia malayi Hint module family protein 0.0058 0.0484 0.107
Loa Loa (eye worm) hypothetical protein 0.0102 0.0963 0.2255
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0019 0.0072 0.0475
Onchocerca volvulus 0.0031 0.0199 0.1141
Schistosoma mansoni lamin 0.0031 0.0199 0.0164
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0619 0.1388
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0019 0.0072 0.0048
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0108 0.0712
Echinococcus granulosus dna polymerase eta 0.0023 0.0108 0.0099
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0022 0.0095 0.0624
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0019 0.0072 0.0475
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0164 0.0199
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0014 0.0014 0.0033
Echinococcus multilocularis tubulin subunit TubB 0.0018 0.0061 0.0036
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0019 0.0072 0.008
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0019 0.0072 0.3391
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0019 0.0072 0.0475
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.0314 0.0734
Leishmania major farnesyltransferase beta subunit 0.0019 0.0072 0.0063
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0022 0.0095 0.0624
Giardia lamblia DINP protein human, muc B family 0.0023 0.0108 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0351 0.0385
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0099 1
Trypanosoma brucei Emopamil binding protein, putative 0.0152 0.1509 0.2199
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0314 0.0422
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0019 0.0072 0.0169
Onchocerca volvulus 0.0109 0.104 0.6827
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0068 0.0089
Echinococcus multilocularis tubulin alpha 3 chain 0.0018 0.0061 0.0036
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1509 0.2199
Loa Loa (eye worm) hypothetical protein 0.0022 0.0095 0.0222
Mycobacterium tuberculosis Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) 0.0041 0.0309 0.3746
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0022 0.0095 0.0235
Echinococcus granulosus tubulin alpha chain 0.0018 0.0061 0.0043
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0164 0.0199
Onchocerca volvulus 0.0041 0.0309 0.1889
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0164 0.0664
Schistosoma mansoni hypothetical protein 0.0032 0.021 0.0178
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0022 0.0095 0.0235
Mycobacterium ulcerans methoxy mycolic acid synthase 2, MmaA2 0.0041 0.0309 0.1665
Loa Loa (eye worm) hypothetical protein 0.007 0.0615 0.1439
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0619 0.1449
Leishmania major hypothetical protein, conserved 0.0152 0.1509 0.2199
Loa Loa (eye worm) TAR-binding protein 0.007 0.0619 0.1449
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0022 0.0095 0.8941
Loa Loa (eye worm) alpha-tubulin 0.0018 0.0061 0.0142
Echinococcus granulosus alpha tubulin 0.0018 0.0061 0.0043
Brugia malayi alpha-tubulin 0.0018 0.0061 0.0072
Echinococcus multilocularis GPCR, family 2 0.0032 0.021 0.0186
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.0311 0.3222 0.7526
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0963 0.22
Mycobacterium ulcerans mycolic acid synthase UmaA 0.0041 0.0309 0.1665
Loa Loa (eye worm) tubulin alpha chain 0.0018 0.0061 0.0142
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0108 0.063
Mycobacterium tuberculosis Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) 0.0041 0.0309 0.3746
Echinococcus multilocularis lamin 0.0031 0.0199 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0164 0.1494
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0108 0.0084
Loa Loa (eye worm) hypothetical protein 0.0041 0.0309 0.0724
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0108 0.0116
Loa Loa (eye worm) hypothetical protein 0.0041 0.0309 0.0724
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0199 0.0398
Loa Loa (eye worm) tubulin alpha 2 0.0014 0.0014 0.0033
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0615 0.1379
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0408 0.4272 0.6305
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0351 0.0821
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.1899 0.1879
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0068 0.0252
Entamoeba histolytica tubulin alpha chain, putative 0.0018 0.0061 0.0205
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.1809
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0043
Schistosoma mansoni tar DNA-binding protein 0.007 0.0619 0.0662
Leishmania major sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Loa Loa (eye worm) hypothetical protein 0.0058 0.0484 0.1133
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0022 0.0095 0.0083
Echinococcus granulosus tubulin alpha chain 0.0018 0.0061 0.0043
Trypanosoma cruzi lanosterol synthase, putative 0.0142 0.14 0.2037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0095 0.0222
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.003 0.0197
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0153 0.152 0.3514
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0068 0.0051
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0019 0.0072 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0963 0.22
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0108 0.0116
Mycobacterium ulcerans methoxy mycolic acid synthase 3, MmaA3 0.0041 0.0309 0.1665
Echinococcus granulosus tubulin alpha 3 chain 0.0018 0.0061 0.0043
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0041 0.0309 0.0415
Echinococcus multilocularis Tubulin alpha 1 chain 0.0018 0.0061 0.0036
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0008
Echinococcus granulosus bloom syndrome protein 0.0022 0.0099 0.0088
Trichomonas vaginalis tubulin epsilon chain, putative 0.0018 0.0061 0.0399
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0019 0.0072 0.0283
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0199 0.0465
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0314 0.1903
Echinococcus granulosus GPCR family 2 0.0032 0.021 0.022
Onchocerca volvulus 0.0031 0.0199 0.1141
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0164 0.1494
Brugia malayi Cytochrome P450 family protein 0.0028 0.0164 0.0316
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0019 0.0072 0.0475
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.021 0.0186
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0164 0.0664
Loa Loa (eye worm) hypothetical protein 0.0208 0.2116 0.4953
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0019 0.0072 0.0048
Echinococcus multilocularis hedgehog 0.0212 0.2152 0.2133
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0022 0.0095 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0351 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0164 0.0664
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0099 0.0075
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.152 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0164 0.0664
Leishmania major DNA polymerase eta, putative 0.0023 0.0108 0.0116
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0164 0.0664
Echinococcus multilocularis tubulin alpha 3 chain 0.0018 0.0061 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.003 0.0197
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0164 0.0384
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0164 0.1494
Brugia malayi RNA binding protein 0.007 0.0619 0.1388
Echinococcus granulosus Tubulin alpha 1 chain 0.0018 0.0061 0.0043
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0019 0.0072 0.01
Loa Loa (eye worm) hypothetical protein 0.0151 0.1497 0.3505
Schistosoma mansoni alpha glucosidase 0.0042 0.0314 0.03
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0164 0.1494
Loa Loa (eye worm) RecQ helicase 0.0022 0.0099 0.0232
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0314 0.0669
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0351 0.0327
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0099 1
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0019 0.0072 0.3391
Plasmodium vivax geranylgeranyltransferase, putative 0.0019 0.0072 0.3391
Giardia lamblia Synaptic glycoprotein SC2 0.0022 0.0095 0.7211
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0164 0.1494
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0164 0.1494
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0164 0.1494
Echinococcus multilocularis geminin 0.0383 0.4006 0.3991
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0108 0.0712
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0022 0.0095 0.0436
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0099 0.0103
Schistosoma mansoni hypothetical protein 0.0383 0.4006 0.468
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0138 0.1354 0.317
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0199 0.0465
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0108 0.063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0351 0.0756
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0164 0.0199
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.0063
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0408 0.4272 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0314 0.2063
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0164 0.1494
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0164 0.0384
Loa Loa (eye worm) cytochrome P450 0.0028 0.0164 0.0384
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0108 0.0116
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0164 0.0199
Brugia malayi Tubulin alpha-2 chain 0.0018 0.0061 0.0072
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0099 0.0088
Echinococcus granulosus tubulin alpha chain 0.0018 0.0061 0.0043
Echinococcus multilocularis microtubule associated protein 2 0.0797 0.8489 0.8486
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0108 0.028
Brugia malayi Muscleblind-like protein 0.0151 0.1497 0.3459
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0008
Mycobacterium tuberculosis Possible fatty acid synthase 0.0041 0.0309 0.3746
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0019 0.0072 0.0063
Echinococcus multilocularis tubulin alpha chain 0.0018 0.0061 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0314 0.2063
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0019 0.0072 0.0057
Brugia malayi Cytochrome P450 family protein 0.0028 0.0164 0.0316
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.021 0.0425
Mycobacterium tuberculosis Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase) 0.0041 0.0309 0.3746
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0041 0.0309 0.3746
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.003 0.0197
Onchocerca volvulus 0.0152 0.1509 1
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Toxoplasma gondii exonuclease III APE 0.0019 0.0068 0.0048
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0019 0.0072 0.0014
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0164 0.0664
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1509 0.2199
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0164 0.1494
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0099 0.0075
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0351 0.0344
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.152 0.2215
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0164 0.0664
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 0.0041 0.0309 0.1665
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0099 0.0088
Echinococcus multilocularis synaptic glycoprotein sc2 0.0022 0.0095 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0351 0.0344
Mycobacterium tuberculosis Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase) 0.0041 0.0309 0.3746
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0099 0.0651
Brugia malayi Tubulin alpha chain 0.0018 0.0061 0.0072
Loa Loa (eye worm) hypothetical protein 0.0151 0.1497 0.3505
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 0.0041 0.0309 0.1665
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1509 0.2199
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0072 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0314 0.0422
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1509 0.2199
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0153 0.152 0.2215
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0099 0.0232
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0019 0.0072 0.01
Trypanosoma brucei alpha tubulin 0.0018 0.0061 0.0045
Brugia malayi cytochrome P450 0.0028 0.0164 0.0316
Leishmania major sterol 24-c-methyltransferase, putative 0.0637 0.6757 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0164 0.0664
Echinococcus granulosus peroxisome assembly protein 26 0.0018 0.0061 0.0043
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0041 0.0309 1
Echinococcus multilocularis peroxisome assembly protein 26 0.0018 0.0061 0.0036
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0365 0.0855
Echinococcus granulosus Tubulin alpha 1 chain 0.0018 0.0061 0.0043
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0108 0.0525
Schistosoma mansoni alpha-glucosidase 0.0162 0.1615 0.1844
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0019 0.0072 0.0014
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.1899 0.1879
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0022 0.0095 0.0436
Brugia malayi Cytochrome P450 family protein 0.0047 0.0365 0.0791
Brugia malayi Hint module family protein 0.0058 0.0484 0.107
Schistosoma mansoni tar DNA-binding protein 0.007 0.0619 0.0662
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0022 0.0095 0.0624
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0056
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0019 0.0072 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Brugia malayi tubulin alpha chain - mouse 0.0018 0.0061 0.0072
Schistosoma mansoni hypothetical protein 0.0154 0.153 0.1744
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0022 0.0095 0.0041
Brugia malayi Tubulin alpha-2 chain 0.0018 0.0061 0.0072
Trypanosoma brucei Sterol methyltransferase, putative 0.0637 0.6757 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0108 0.0116
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0164 0.1494
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0061 0.0399
Leishmania major alpha tubulin 0.0018 0.0061 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.003 0.0197
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0068 0.0056
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0164 0.0664
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0099 0.0163
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0164 0.0664
Echinococcus granulosus lysosomal alpha glucosidase 0.0188 0.1899 0.2214
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.0314 0.0422
Echinococcus granulosus tar DNA binding protein 0.007 0.0619 0.0702
Plasmodium falciparum polyprenol reductase, putative 0.0022 0.0095 0.8941
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0019 0.0072 0.0475
Schistosoma mansoni hypothetical protein 0.007 0.0615 0.0657
Mycobacterium tuberculosis Methoxy mycolic acid synthase 1 MmaA1 (methyl mycolic acid synthase 1) (MMA1) (hydroxy mycolic acid synthase) 0.0041 0.0309 0.3746

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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