Detailed information for compound 1578991

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 406.734 | Formula: C17H22Cl3N3O2
  • H donors: 2 H acceptors: 2 LogP: 4.02 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H](COc1c(Cl)ccc(c1C(=C)n1cncc1)Cl)CNC(C)C.Cl
  • InChi: 1S/C17H21Cl2N3O2.ClH/c1-11(2)21-8-13(23)9-24-17-15(19)5-4-14(18)16(17)12(3)22-7-6-20-10-22;/h4-7,10-11,13,21,23H,3,8-9H2,1-2H3;1H/t13-;/m1./s1
  • InChiKey: DGLQZJPSOFSWLE-BTQNPOSSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adrenoceptor beta 1 References
Homo sapiens adrenoceptor beta 3 Starlite/ChEMBL References
Homo sapiens adrenoceptor beta 2, surface References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0123 0.0227
Brugia malayi GH02984p 0.0384 0.0544 0.5391
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0047 0.0402
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0039 0.0861
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0018 0.0138
Schistosoma mansoni microtubule-associated protein tau 0.3634 0.5375 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0047 0.1031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0008
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0051 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0077 0.0667
Loa Loa (eye worm) thioredoxin reductase 0.0088 0.0104 0.1031
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.0019 0.024
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.0019 0.144
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0011 0.0882
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Brugia malayi Protein cec-1. 0.0025 0.0011 0.0093
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0011 0.0882
Echinococcus granulosus Protein patched homolog 1 0.0219 0.0299 0.0555
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0629 0.0908 0.1688
Brugia malayi CXXC zinc finger family protein 0.0065 0.0069 0.0674
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0019 0.0159
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0022 0.0005 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0629 0.0908 0.1688
Echinococcus granulosus mixed lineage leukemia protein mll 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0027 0.0232
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0131 0.0167 0.031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0116 0.0213
Brugia malayi hypothetical protein 0.0069 0.0076 0.0741
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0006
Brugia malayi Pre-SET motif family protein 0.0696 0.1007 1
Entamoeba histolytica hypothetical protein 0.0036 0.0027 0.0355
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0018 0.0138
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Schistosoma mansoni ran 0.0045 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0011 0.0882
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.004 0.0072
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0054 0.3179
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0054 0.1182
Brugia malayi CHE-14 protein 0.0219 0.0299 0.2962
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0021 0.0205
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.011 0.0137 0.307
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0046 0.0083
Brugia malayi Glutamate receptor 1 precursor 0.0336 0.0473 0.4688
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0019 0.0159
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0509 0.0729 0.1355
Echinococcus multilocularis neuropeptide receptor 0.0629 0.0908 0.0907
Schistosoma mansoni glutamate receptor AMPA 0.0336 0.0473 0.0878
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0153 0.1211
Echinococcus granulosus epidermal growth factor receptor 0.0058 0.0059 0.0108
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0038 0.0036
Onchocerca volvulus 0.0629 0.0908 0.7874
Brugia malayi DKFZp564C0469 protein 0.0031 0.0019 0.0175
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0069 0.0076 0.0752
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0051 0.0502
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0629 0.0908 0.0907
Brugia malayi putative neuropeptide receptor NPR1 0.0629 0.0908 0.9011
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0079 0.0091 0.009
Schistosoma mansoni hypothetical protein 0.0629 0.0908 0.1688
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Brugia malayi Dopamine receptor 0.0629 0.0908 0.9011
Toxoplasma gondii rhodanese family domain-containing protein 0.0036 0.0027 0.1578
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Echinococcus granulosus hypothetical protein 0.0629 0.0908 0.1688
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0005 0.0006
Echinococcus multilocularis serine protein kinase ATM 0.0043 0.0038 0.0036
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0018 0.1047
Loa Loa (eye worm) neuropeptide F receptor 0.0629 0.0908 0.9012
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0629 0.0908 0.9012
Schistosoma mansoni tar DNA-binding protein 0.0204 0.0276 0.0512
Echinococcus granulosus 7TM GPCR rhodopsin 0.0629 0.0908 0.1688
Schistosoma mansoni polycystin 1-related 0.0069 0.0076 0.0139
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis neuropeptide Y receptor 0.0629 0.0908 0.0907
Echinococcus multilocularis solute carrier family 5 0.0042 0.0036 0.0035
Schistosoma mansoni rab6-interacting 0.0069 0.0076 0.0139
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0629 0.0908 0.1688
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0034 0.0643
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Echinococcus multilocularis geminin 0.0695 0.1006 0.1005
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0006
Echinococcus granulosus neuropeptide s receptor 0.1118 0.1635 0.304
Mycobacterium ulcerans hypothetical protein 0.0025 0.001 0.0068
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.01 0.079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0051 0.0491
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.005 0.0047 0.1031
Loa Loa (eye worm) hypothetical protein 0.0429 0.0611 0.6064
Toxoplasma gondii hypothetical protein 0.0031 0.0019 0.1094
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0026 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Brugia malayi Calcitonin receptor-like protein seb-1 0.037 0.0522 0.5179
Echinococcus multilocularis dro:myosuppressin receptor 0.0629 0.0908 0.0907
Echinococcus granulosus g protein coupled receptor 0.0629 0.0908 0.1688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0109 0.0946
Brugia malayi Sodium:solute symporter family protein 0.0042 0.0036 0.0346
Toxoplasma gondii target of rapamycin (TOR), putative 0.0087 0.0102 0.6141
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.0291 0.6536
Echinococcus multilocularis nmda type glutamate receptor 0.2268 0.3344 0.3343
Onchocerca volvulus 0.0069 0.0076 0.0579
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Plasmodium vivax rhodanese like protein, putative 0.0036 0.0027 0.2127
Mycobacterium tuberculosis Conserved protein 0.0025 0.001 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0015 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0198 0.0197
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.001 0.0016
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0036 0.0026 0.0197
Brugia malayi GnHR receptor homolog 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0193
Echinococcus granulosus Niemann Pick C1 protein 0.0511 0.0733 0.1362
Schistosoma mansoni glutamate receptor kainate 0.0336 0.0473 0.0878
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0109 0.0946
Loa Loa (eye worm) hypothetical protein 0.009 0.0107 0.1067
Loa Loa (eye worm) DR-78 0.0025 0.001 0.0096
Brugia malayi hypothetical protein 0.018 0.0241 0.2383
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.001 0.008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0117 0.0147 0.0146
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0696 0.1007 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0088 0.0104 0.0819
Schistosoma mansoni hypothetical protein 0.0212 0.0287 0.0533
Schistosoma mansoni hypothetical protein 0.0117 0.0147 0.0271
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.004 0.0876
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0153 0.1211
Trypanosoma cruzi extracellular receptor, putative 0.0172 0.0229 0.5154
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0039 0.0861
Echinococcus granulosus G protein coupled receptor 139 0.0629 0.0908 0.1688
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.001 0.0016
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0018 0.0389
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.0036 0.0027 0.2127
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.001 0.0008
Echinococcus multilocularis g-protein coupled receptor 0.0629 0.0908 0.0907
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0336 0.0473 0.0472
Toxoplasma gondii patched family protein 0.0031 0.0019 0.1094
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Loa Loa (eye worm) TK/INSR protein kinase 0.0127 0.0162 0.1606
Echinococcus granulosus glutamate receptor 2 0.0509 0.0729 0.1355
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0047 0.1031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.001 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0051 0.0092
Plasmodium falciparum rhodanese like protein, putative 0.0036 0.0027 0.2443
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0629 0.0908 0.0907
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.0444 1
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) patched family protein 0.0031 0.0019 0.0191
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.001 0.0068
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0021 0.044
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0153 0.1211
Brugia malayi Uncoordinated protein 44 0.0031 0.002 0.0185
Brugia malayi Niemann-Pick C1 protein precursor 0.0511 0.0733 0.7273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0026 0.0257
Toxoplasma gondii patched family protein 0.0031 0.0019 0.1094
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0043 0.0038 0.082
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0629 0.0908 0.1688
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.001 0.0068
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0051 0.0491
Leishmania major phosphatidylinositol 3-related kinase, putative 0.005 0.0047 0.1031
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0172 0.0229 0.2276
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0011 0.0087
Brugia malayi PXA domain containing protein 0.0021 0.0005 0.0034
Echinococcus multilocularis somatostatin receptor 0.0629 0.0908 0.0907
Onchocerca volvulus 0.0126 0.0161 0.1324
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0652 0.0943 0.9356
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0063 0.3757
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0005 0.0045
Entamoeba histolytica protein kinase rad3, putative 0.0028 0.0015 0.0185
Trichomonas vaginalis chromobox protein, putative 0.009 0.0106 0.0919
Echinococcus multilocularis allatostatin A receptor 0.0629 0.0908 0.0907
Brugia malayi Rhodanese-like domain containing protein 0.0036 0.0027 0.0258
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Schistosoma mansoni protein kinase 0.0173 0.0231 0.0427
Echinococcus multilocularis chromobox protein 1 0.009 0.0106 0.0105
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0026 0.0197
Loa Loa (eye worm) hypothetical protein 0.0083 0.0096 0.0955
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0011 0.0569
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0051 0.0491
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.005 0.0047 0.1031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0005 0.0034
Mycobacterium tuberculosis Probable oxidoreductase 0.0223 0.0305 0.2421
Schistosoma mansoni biogenic amine (5HT) receptor 0.0629 0.0908 0.1688
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0036 0.0027 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0051 0.0491
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0018 0.0389
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0026 0.0197
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0019 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0231
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.0036 0.0027 0.0207
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0005 0.0034
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0509 0.0729 0.0728
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0051 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.007 0.0606
Loa Loa (eye worm) TAR-binding protein 0.0204 0.0276 0.2742
Schistosoma mansoni tyrosine kinase 0.0057 0.0057 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0007 0.0055
Schistosoma mansoni single-minded 0.0054 0.0053 0.0096
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0011 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0051 0.0491
Echinococcus multilocularis microtubule associated protein 2 0.3634 0.5375 0.5374
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0046
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0051 0.0092
Schistosoma mansoni opsin-like receptor 0.0629 0.0908 0.1688
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0096 0.0177
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0005 0.0003
Echinococcus granulosus somatostatin receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Brugia malayi chromobox protein homolog 3 0.0056 0.0056 0.0544
Brugia malayi intermediate filament protein 0.0056 0.0056 0.0547
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0172 0.0229 0.2276
Onchocerca volvulus 0.0466 0.0665 0.5744
Schistosoma mansoni myosin xvIII 0.0629 0.0908 0.1688
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0018 0.0389
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0153 0.4892
Brugia malayi hypoxia-induced factor 1 0.0166 0.022 0.2177
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0034 0.3069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0087
Echinococcus granulosus neuropeptide Y receptor 0.0629 0.0908 0.1688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0645
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0101 0.0123 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0123 0.0227
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0008 0.0399
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0198 0.1958
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0172 0.0229 0.0228
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0079 0.0091 0.0785
Giardia lamblia GTOR 0.011 0.0137 0.2677
Schistosoma mansoni nuclear hormone receptor 0.0025 0.001 0.0016
Brugia malayi Pre-SET motif family protein 0.0101 0.0123 0.1213
Echinococcus granulosus expressed protein 0.0412 0.0586 0.1088
Loa Loa (eye worm) glutamate receptor 0.0172 0.0229 0.2276
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.022 0.2186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0082 0.0708
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0051 0.0049
Brugia malayi Rhodanese-like domain containing protein 0.0466 0.0665 0.6596
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0361 0.0509 0.6938
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0051 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0201 0.0271 0.2156
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0018 0.6635
Schistosoma mansoni tyrosine kinase 0.0057 0.0057 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Brugia malayi Guanylyl cyclase protein 23 0.0173 0.0231 0.2282
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0008 0.0066
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0117 0.0147 0.0146
Loa Loa (eye worm) glutamate receptor 1 0.0336 0.0473 0.4694
Schistosoma mansoni biogenic amine receptor 0.0629 0.0908 0.1688
Schistosoma mansoni tyrosine kinase 0.0058 0.0059 0.0108
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0014 0.0024
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0036 0.0026 0.0197
Mycobacterium ulcerans putative regulatory protein 0.004 0.0032 0.0248
Brugia malayi glutathione reductase 0.0088 0.0104 0.102
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0629 0.0908 0.9012
Plasmodium vivax SET domain protein, putative 0.0101 0.0123 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0087
Schistosoma mansoni hypothetical protein 0.0117 0.0147 0.0271
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0099 0.0121 0.0222
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0153 0.1211
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0862 0.1254 1
Echinococcus granulosus death domain containing protein 0.0031 0.002 0.0035
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0005 0.0006
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0051 0.0092
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0051 0.0359
Schistosoma mansoni glutamate receptor kainate 0.0336 0.0473 0.0878
Loa Loa (eye worm) hypothetical protein 0.0079 0.0091 0.09
Echinococcus multilocularis fmrfamide receptor 0.0629 0.0908 0.0907
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0629 0.0908 0.9012
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0153 0.4892
Loa Loa (eye worm) patched family protein 0.0031 0.0019 0.0191
Schistosoma mansoni tyrosine kinase 0.0057 0.0057 0.0105
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.004 0.2355
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0105
Loa Loa (eye worm) hypothetical protein 0.0069 0.0076 0.0752
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.004 0.0876
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.018 0.0241 0.2392
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0011 0.0768
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0008 0.0052
Echinococcus granulosus insulin receptor 0.0127 0.0162 0.0299
Schistosoma mansoni hypothetical protein 0.0131 0.0167 0.031
Onchocerca volvulus 0.0052 0.0051 0.0359
Brugia malayi nuclear receptor RXR 0.0028 0.0014 0.0128
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.002 0.0035
Echinococcus granulosus neuropeptide FF receptor 2 0.0629 0.0908 0.1688
Brugia malayi hypothetical protein 0.0054 0.0054 0.052
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0036 0.0026 0.0197
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.005 0.0047 0.0085
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0109 0.0946
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0011 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0153 0.1508
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0028 0.0015 0.0014
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0039 0.2317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Echinococcus multilocularis Ankyrin 0.0032 0.002 0.0019
Echinococcus granulosus cpg binding protein 0.0068 0.0075 0.0136
Echinococcus multilocularis musashi 0.0056 0.0056 0.0055
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Toxoplasma gondii hypothetical protein 0.0051 0.0049 0.2908
Schistosoma mansoni sodium/solute symporter 0.0042 0.0036 0.0065
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.0036 0.0027 0.0048
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0006
Echinococcus multilocularis tyrosine kinase 0.0173 0.0231 0.023
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0336 0.0473 0.0472
Echinococcus granulosus sodium:glucose cotransporter 2 0.0042 0.0036 0.0065
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0128
Brugia malayi hypothetical protein 0.0079 0.0091 0.089
Echinococcus multilocularis neuropeptide FF receptor 2 0.0629 0.0908 0.0907
Brugia malayi Rhodanese-like domain containing protein 0.0466 0.0665 0.6596
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0201 0.0271 0.2156
Echinococcus granulosus single minded 2 0.0043 0.0037 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Leishmania major mitochondrial DNA polymerase beta 0.0317 0.0444 1
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.0291 0.6536
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0172 0.0229 0.0228
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0018 0.1412
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0629 0.0908 0.1688
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0035 0.0063
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0153 0.2074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0051 0.0502
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0009 0.0015
Echinococcus granulosus allatostatin A receptor 0.0629 0.0908 0.1688
Echinococcus granulosus netrin receptor unc 5 0.0031 0.002 0.0035
Brugia malayi metabotropic glutamate receptor type 2 0.0172 0.0229 0.2267
Echinococcus granulosus g protein coupled receptor 0.0629 0.0908 0.1688
Echinococcus granulosus fmrfamide receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0016 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0026 0.0246
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0063 0.1397
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0051 0.0092
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Echinococcus granulosus metabotropic glutamate receptor 5 0.0172 0.0229 0.0425
Echinococcus granulosus nibrin 0.0031 0.0019 0.0033
Schistosoma mansoni cpg binding protein 0.0068 0.0075 0.0136
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.002 0.0035
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.0036 0.0027 0.0269
Onchocerca volvulus 0.0056 0.0056 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0051 0.0491
Giardia lamblia DNA repair protein RAD52 0.0361 0.0509 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.011 0.0137 0.1857
Brugia malayi G-protein coupled receptor 0.0629 0.0908 0.9011
Schistosoma mansoni neuropeptide receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Schistosoma mansoni amine GPCR 0.0629 0.0908 0.1688
Brugia malayi Receptor family ligand binding region containing protein 0.0173 0.0231 0.2282
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0006
Echinococcus granulosus neuropeptides capa receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis G protein coupled receptor 139 0.0629 0.0908 0.0907
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.0019 0.1068
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0051 0.0491
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0003
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.004 0.0397
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Brugia malayi RNA binding protein 0.0204 0.0276 0.2733
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0157
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0336 0.0473 0.0878
Echinococcus granulosus high affinity choline transporter 1 0.0384 0.0544 0.101
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0021 0.044
Onchocerca volvulus 0.0031 0.0019 0.0084
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0051 0.0502
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0011 0.0087
Echinococcus multilocularis protein dispatched 1 0.025 0.0345 0.0344
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0051 0.0049
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0053 0.0096
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0101 0.0123 0.7416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.001 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.002 0.0197
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0051 0.0491
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Plasmodium falciparum glutathione reductase 0.003 0.0018 0.1621
Echinococcus granulosus equilibrative nucleoside transporter 0.0079 0.0091 0.0167
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0051 0.0092
Mycobacterium leprae Conserved hypothetical protein 0.0036 0.0027 0.0654
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.0019 0.0159
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.002 0.0019
Entamoeba histolytica hypothetical protein 0.0259 0.0358 0.4871
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Echinococcus granulosus peptide allatostatin:somatostatin 0.0629 0.0908 0.1688
Brugia malayi TAR-binding protein 0.0204 0.0276 0.2733
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0006 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.001 0.0084
Schistosoma mansoni topbp1 0.0031 0.0019 0.0033
Echinococcus granulosus chromobox protein 2 0.0025 0.0011 0.0017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0196 0.4399
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0036 0.0027 0.0207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.001 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0109 0.0946
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0039 0.0861
Entamoeba histolytica hypothetical protein 0.005 0.0047 0.0623
Schistosoma mansoni tar DNA-binding protein 0.0204 0.0276 0.0512
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0466 0.0665 0.1235
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0629 0.0908 0.9011
Brugia malayi steroid hormone receptor 0.0052 0.0051 0.0491
Chlamydia trachomatis DNA ligase 0.0031 0.0019 0.0088
Echinococcus granulosus glutamate receptor subunit protein glur 0.0336 0.0473 0.0878
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus epidermal growth factor receptor 0.0058 0.0059 0.0108
Trichomonas vaginalis cdc25c, putative 0.0036 0.0027 0.0232
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0042 0.0036 0.0065
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0629 0.0908 0.1688
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0629 0.0908 0.0907
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0096 0.0177
Brugia malayi hypothetical protein 0.0039 0.0031 0.03
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0153 0.1211
Onchocerca volvulus 0.0044 0.0039 0.0259
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0026 0.0559
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0629 0.0908 0.0907
Brugia malayi Myosin head containing protein 0.0031 0.0019 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0027 0.0587
Brugia malayi Receptor family ligand binding region containing protein 0.0172 0.0229 0.2267
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.0036 0.0027 0.2443
Echinococcus multilocularis dnaJ subfamily B 0.049 0.0702 0.0701
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0373
Schistosoma mansoni hypothetical protein 0.0695 0.1006 0.187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0051 0.0502
Schistosoma mansoni neuropeptide f receptor 76f 0.0629 0.0908 0.1688
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus sodium:myo inositol cotransporter 0.0042 0.0036 0.0065
Treponema pallidum NADH oxidase 0.003 0.0018 0.0138
Brugia malayi G protein-coupled receptor F59B2.13 0.0629 0.0908 0.9011
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0099 0.0121 0.0119
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0026 0.0559
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0032 0.0031
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0014 0.0024
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0043 0.0038 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0644
Onchocerca volvulus 0.0629 0.0908 0.7874
Loa Loa (eye worm) TYRA-2 protein 0.0629 0.0908 0.9012
Echinococcus granulosus centrosomal protein of 41 kDa 0.0036 0.0027 0.0048
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Onchocerca volvulus 0.0172 0.0229 0.1926
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0007 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Schistosoma mansoni high-affinity choline transporter 0.0384 0.0544 0.101
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0036 0.0027 0.0232
Schistosoma mansoni hypothetical protein 0.0043 0.0038 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0157
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.0036 0.0027 0.0207
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0018 0.0138
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Onchocerca volvulus Neuropeptide F receptor homolog 0.0629 0.0908 0.7874
Schistosoma mansoni patched 1 0.0219 0.0299 0.0555
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Chlamydia trachomatis hypothetical protein 0.0036 0.0027 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0645
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Echinococcus multilocularis centrosomal protein of 41 kDa 0.0036 0.0027 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0047 0.0465
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0038 0.2982
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0027 0.0207
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus multilocularis chromobox protein 1 0.009 0.0106 0.0105
Echinococcus multilocularis Chromo domain 0.0025 0.0011 0.0009
Schistosoma mansoni dual specificity protein phosphatase 0.0036 0.0027 0.0048
Trypanosoma cruzi target of rapamycin kinase 3 0.0092 0.0109 0.2445
Loa Loa (eye worm) hypothetical protein 0.0042 0.0036 0.0358
Echinococcus multilocularis epidermal growth factor receptor 0.0058 0.0059 0.0058
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0038 0.0362
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.001 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0022 0.0005 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0126 0.0161 0.0297
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0862 0.1254 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0629 0.0908 0.0907
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0153 0.2074
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0117 0.0147 0.0271
Onchocerca volvulus 0.0031 0.0019 0.008
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0159
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0001 0.0012
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0026 0.0197
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Onchocerca volvulus 0.0629 0.0908 0.7874
Brugia malayi RIKEN cDNA 4930451A13 0.0036 0.0027 0.0258
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0629 0.0908 0.1688
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0117 0.0147 0.0271
Plasmodium vivax thioredoxin reductase, putative 0.0088 0.0104 0.8408
Echinococcus granulosus alpha 1A adrenergic receptor 0.0629 0.0908 0.1688
Onchocerca volvulus 0.004 0.0032 0.0198
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.0019 0.0018
Schistosoma mansoni growth hormone secretagogue receptor 0.0629 0.0908 0.1688
Echinococcus granulosus lamin dm0 0.0056 0.0056 0.0102
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.0019 0.6768
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0039 0.0338
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0204 0.0276 0.2742
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.002 0.0019
Brugia malayi Cytochrome P450 family protein 0.0032 0.0021 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Schistosoma mansoni hypothetical protein 0.049 0.0702 0.1304
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.004 0.0385
Schistosoma mansoni nuclear receptor 0.0025 0.001 0.0016
Echinococcus granulosus receptor type guanylyl cyclase 0.0173 0.0231 0.0427
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0026 0.0559
Schistosoma mansoni tyrosine kinase 0.0173 0.0231 0.0427
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.0026 0.2327
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0629 0.0908 0.1688
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0032 0.0276
Loa Loa (eye worm) hypothetical protein 0.0117 0.0147 0.1458
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.011 0.0137 0.307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.037 0.0522 0.5184
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0002 0.0001
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0105 0.0192
Echinococcus multilocularis mixed lineage leukemia protein mll 0.002 0.0002 0.0001
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Brugia malayi hypothetical protein 0.0031 0.0019 0.0179
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0027 0.0355
Loa Loa (eye worm) hypothetical protein 0.0125 0.0158 0.1573
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0031
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0064 0.0063
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0061 0.0525
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0018 0.1621
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.009 0.0107 0.0848
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0232
Echinococcus multilocularis heat shock protein 67b2 0.0036 0.0027 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0082 0.0706
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0131 0.0167 0.0166
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0008 0.0399
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0011 0.0569
Onchocerca volvulus 0.0031 0.0019 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Echinococcus multilocularis glutamate receptor 2 0.0509 0.0729 0.0728
Echinococcus multilocularis neuropeptides capa receptor 0.0629 0.0908 0.0907
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.0036 0.0027 0.0232
Brugia malayi AKH receptor 0.0629 0.0908 0.9011
Leishmania major trypanothione reductase 0.0088 0.0104 0.2319
Trichomonas vaginalis cdc25b, putative 0.0466 0.0665 0.578
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Entamoeba histolytica hypothetical protein 0.0031 0.0019 0.024
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Loa Loa (eye worm) hypothetical protein 0.0031 0.002 0.0197
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0047 0.0454
Schistosoma mansoni tyrosine kinase 0.0127 0.0162 0.0299
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0006
Echinococcus granulosus neuropeptide receptor 0.0629 0.0908 0.1688
Brugia malayi Patched protein homolog 1 0.0031 0.0019 0.0179
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0051 0.0049
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0047 0.0043 0.0939
Leishmania major cytochrome p450-like protein 0.0032 0.0021 0.044
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) patched family protein 0.0031 0.0019 0.0191
Schistosoma mansoni neuropeptide receptor 0.0629 0.0908 0.1688
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0026 0.0246
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0189
Brugia malayi neuropeptide F receptor 0.0629 0.0908 0.9011
Brugia malayi neuropeptide F receptor 0.0629 0.0908 0.9011
Schistosoma mansoni biogenic amine receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0127 0.0162 0.0161
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0019 0.0397
Echinococcus granulosus glutamate receptor NMDA 0.2096 0.3088 0.5744
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0193 0.026 0.0483
Brugia malayi SET domain containing protein 0.003 0.0018 0.0168
Schistosoma mansoni hypothetical protein 0.0212 0.0287 0.0533
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Echinococcus granulosus snurportin 1 0.0652 0.0943 0.1752
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0005 0.0006
Onchocerca volvulus 0.0042 0.0036 0.0231
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0519 0.0745 0.1384
Trichomonas vaginalis set domain proteins, putative 0.0792 0.115 1
Schistosoma mansoni tyrosine kinase 0.0173 0.0231 0.0427
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0019 0.0159
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0038 0.0361
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni amine GPCR 0.0629 0.0908 0.1688
Schistosoma mansoni lamin 0.0056 0.0056 0.0102
Echinococcus granulosus neuropeptide receptor A26 0.1118 0.1635 0.304
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0026 0.0221
Trichomonas vaginalis cdc25c, putative 0.0466 0.0665 0.578
Trichomonas vaginalis cdc25a, putative 0.0036 0.0027 0.0232
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0018 0.0171
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0051 0.0092
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0466 0.0665 0.578
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.003 0.0282
Brugia malayi Death domain containing protein 0.0031 0.002 0.0185
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Echinococcus multilocularis neuropeptides capa receptor 0.0629 0.0908 0.0907
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0014 0.0139
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0198 0.0367
Brugia malayi conserved hypotetical protein 0.0025 0.001 0.0084
Onchocerca volvulus 0.0173 0.0231 0.1939
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Schistosoma mansoni netrin receptor unc5 0.0031 0.002 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0159
Echinococcus multilocularis snurportin 1 0.0652 0.0943 0.0942
Echinococcus granulosus GPCR family 2 0.0117 0.0147 0.0271
Onchocerca volvulus 0.0629 0.0908 0.7874
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Entamoeba histolytica hypothetical protein 0.0172 0.0229 0.3118
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0056 0.0558
Echinococcus granulosus neuropeptides capa receptor 0.0629 0.0908 0.1688
Schistosoma mansoni chromobox protein 0.0025 0.0011 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0153 0.3428
Echinococcus granulosus intermediate filament protein 0.0056 0.0056 0.0102
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0245 0.0454
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Leishmania major hypothetical protein, conserved 0.0214 0.0291 0.6536
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0036 0.0027 0.0207
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0008 0.2528
Echinococcus multilocularis neuropeptide receptor 0.0629 0.0908 0.0907
Brugia malayi nuclear receptor NHR-88 0.0025 0.001 0.0084
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0015 0.0134
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0047 0.0402
Echinococcus multilocularis lipoxygenase domain containing protein 0.0069 0.0076 0.0075
Echinococcus multilocularis Niemann Pick C1 protein 0.0731 0.1059 0.1058
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0026 0.0197
Trichomonas vaginalis hypothetical protein 0.0025 0.0011 0.0087
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0006
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0046
Schistosoma mansoni metabotropic glutamate receptor 0.0172 0.0229 0.0425
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0018 0.0175
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0051 0.0491
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0039 0.2317
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0011 0.0093
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0629 0.0908 0.1688
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0042 0.0036 0.0035
Schistosoma mansoni zinc finger protein 0.0025 0.001 0.0016
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.0036 0.0027 0.0207
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0056 0.0482
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Trichomonas vaginalis ran, putative 0.0045 0.004 0.0343
Brugia malayi hypothetical protein 0.0172 0.0229 0.2267
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0036 0.0026 0.0197
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.009 0.0107 0.08
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Echinococcus multilocularis G-protein coupled receptor, putative 0.0629 0.0908 0.0907
Plasmodium falciparum thioredoxin reductase 0.0088 0.0104 0.9657
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0051 0.0092
Brugia malayi follicle stimulating hormone receptor 0.0629 0.0908 0.9011
Plasmodium falciparum thioredoxin reductase 0.003 0.0018 0.1621
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0139
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0064 0.1417
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0014 0.0024
Brugia malayi Heterochromatin protein 1 0.009 0.0106 0.1044
Brugia malayi hypothetical protein 0.0028 0.0014 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0105 0.0908
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0051 0.0491
Trypanosoma brucei hypothetical protein, conserved 0.0214 0.0291 0.6536
Loa Loa (eye worm) RGC/RGC protein kinase 0.0173 0.0231 0.2291
Echinococcus multilocularis nibrin 0.0031 0.0019 0.0018
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Echinococcus multilocularis lamin dm0 0.0056 0.0056 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0054 0.4924
Schistosoma mansoni hypothetical protein 0.0695 0.1006 0.187
Brugia malayi Melatonin receptor type 1A 0.0629 0.0908 0.9011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.007 0.0606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0051 0.0502
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0026 0.0246
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0018 0.6635
Schistosoma mansoni hypothetical protein 0.0629 0.0908 0.1688
Schistosoma mansoni inositol transporter 0.0042 0.0036 0.0065
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.001 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0629 0.0908 0.0907
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.001 0.0008
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0158 0.1559
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0011 0.0768
Schistosoma mansoni neuropeptide receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0219 0.0299 0.297
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0006
Brugia malayi hypothetical protein 0.0125 0.0158 0.1563
Toxoplasma gondii FATC domain-containing protein 0.0043 0.0038 0.2206
Echinococcus multilocularis expressed protein 0.0412 0.0586 0.0585
Brugia malayi FAT domain containing protein 0.0022 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0018 0.0156
Loa Loa (eye worm) hypothetical protein 0.0466 0.0665 0.66
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0629 0.0908 0.9011
Echinococcus granulosus g protein coupled receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni tar DNA-binding protein 0.0204 0.0276 0.0512
Brugia malayi RNA recognition motif domain containing protein 0.0204 0.0276 0.2733
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0259 0.0358 0.0663
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0026 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0015 0.0126
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0051 0.0092
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0196 0.4399
Schistosoma mansoni ran 0.0045 0.004 0.0072
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Leishmania major hypothetical protein, unknown function 0.0036 0.0027 0.0587
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0153 0.1211
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0018 0.1621
Brugia malayi hypothetical protein 0.0025 0.001 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0629 0.0908 0.9012
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0038 0.0322
Onchocerca volvulus 0.0031 0.0019 0.0084
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0042 0.0036 0.2118
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0008 0.0148
Schistosoma mansoni hypothetical protein 0.0036 0.0027 0.0048
Echinococcus multilocularis lamin 0.0056 0.0056 0.0055
Schistosoma mansoni adenoreceptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0105
Plasmodium vivax patched family protein, putative 0.0031 0.0019 0.1476
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0021 0.0155
Loa Loa (eye worm) hypothetical protein 0.0061 0.0064 0.0635
Schistosoma mansoni neuropeptide F-like receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0063 0.0062
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0026 0.0046
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.1198 0.1754 0.1753
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0016 0.0028
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0011 0.0093
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0042 0.0036 0.0035
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0011 0.0017
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0026 0.0246
Entamoeba histolytica hypothetical protein 0.0259 0.0358 0.4871
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0026 0.1502
Brugia malayi hypothetical protein 0.0021 0.0005 0.0034
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0016 0.0159
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0079 0.0091 0.0785
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0051 0.0092
Echinococcus granulosus Chromo domain 0.0025 0.0011 0.0017
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0509 0.0729 0.0728
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0223 0.0305 0.2421
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0219 0.0299 0.297
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0336 0.0473 0.0472
Echinococcus multilocularis protein patched 0.0219 0.0299 0.0298
Onchocerca volvulus 0.0069 0.0076 0.0579
Onchocerca volvulus 0.0121 0.0153 0.1256
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0069 0.0685
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni hypothetical protein 0.0212 0.0287 0.0533
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0629 0.0908 0.1688
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0051 0.0502
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Onchocerca volvulus 0.0083 0.0096 0.0759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0645
Entamoeba histolytica hypothetical protein 0.0259 0.0358 0.4871
Echinococcus granulosus histone lysine methyltransferase setb 0.0101 0.0123 0.0227
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.0019 0.0175
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.0026 0.0197
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0036 0.0027 0.0048
Onchocerca volvulus 0.0056 0.0056 0.0408
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.004 0.0876
Onchocerca volvulus Protein patched homolog 0.0031 0.0019 0.0084
Brugia malayi Protein kinase domain containing protein 0.0127 0.0162 0.1596
Loa Loa (eye worm) hypothetical protein 0.0511 0.0733 0.7276
Echinococcus granulosus microtubule associated protein 2 0.3634 0.5375 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0092 0.0109 0.2445
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Brugia malayi protein C24B5.3 0.0031 0.0019 0.0179
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0079 0.0091 0.0167
Echinococcus multilocularis tar DNA binding protein 0.0204 0.0276 0.0275
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0005 0.0045
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0117 0.0147 0.0271
Echinococcus multilocularis g protein coupled receptor 0.0629 0.0908 0.0907
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0051 0.0359
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0036 0.0027 0.0232
Echinococcus multilocularis chromobox protein 2 0.0025 0.0011 0.0009
Echinococcus granulosus orexin receptor type 2 0.0629 0.0908 0.1688
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0009 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.01 0.079
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0172 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Loa Loa (eye worm) hypothetical protein 0.0384 0.0544 0.5397
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0026 0.0612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0051 0.0502
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0862 0.1254 1
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0079 0.0091 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0137 0.1188
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0096 0.0095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0018 0.0032
Echinococcus granulosus g-protein coupled receptor 0.0629 0.0908 0.1688
Brugia malayi bHLH-PAS transcription factor 0.004 0.0032 0.0308
Brugia malayi nuclear hormone receptor 0.0025 0.001 0.0084
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0051 0.0491
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0026 0.0246
Echinococcus multilocularis glutamate receptor 2 0.0172 0.0229 0.0228
Echinococcus multilocularis high affinity choline transporter 1 0.0384 0.0544 0.0543
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0051 0.0092
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0039 0.3124
Onchocerca volvulus 0.0031 0.0019 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0051 0.0491
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0051 0.0491
Schistosoma mansoni histamine h1 receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0172 0.0229 0.2276
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0026 0.0559
Brugia malayi Patched related family protein 4 0.0031 0.0019 0.0179
Toxoplasma gondii histone lysine methyltransferase SET1 0.013 0.0166 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0117 0.0147 0.1448
Echinococcus granulosus solute carrier family 5 0.0042 0.0036 0.0065
Brugia malayi PAS domain containing protein 0.0054 0.0053 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Brugia malayi G-protein coupled receptor 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni cpg binding protein 0.0065 0.0069 0.0126
Loa Loa (eye worm) heterochromatin protein 1 0.009 0.0106 0.1054
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0005 0.0006
Schistosoma mansoni neuropeptide receptor 0.0629 0.0908 0.1688
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0026 0.0221
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0007 0.0055
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.005 0.0047 0.104
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.002 0.0035
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0018 0.0164
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.011 0.0137 0.0253
Echinococcus granulosus replication factor c subunit 1 0.0031 0.0019 0.0033
Onchocerca volvulus 0.0629 0.0908 0.7874
Loa Loa (eye worm) patched family protein 0.0031 0.0019 0.0191
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.0019 0.0371
Loa Loa (eye worm) histone methyltransferase 0.0024 0.0008 0.0082
Brugia malayi Nucleoside transporter family protein 0.0079 0.0091 0.089
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0629 0.0908 0.9012
Giardia lamblia Hypothetical protein 0.0079 0.0091 0.1764
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.003 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.0036 0.0027 0.0654
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0336 0.0473 0.0472
Schistosoma mansoni tyrosine kinase 0.0127 0.0162 0.0299
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.0036 0.0027 0.0258
Brugia malayi RNA, U transporter 1 0.0174 0.0231 0.2287
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0092 0.0109 0.2445
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0046 0.0455
Echinococcus granulosus nmda type glutamate receptor 0.2268 0.3344 0.6221
Echinococcus multilocularis serotonin receptor 0.0629 0.0908 0.0907
Echinococcus granulosus neuropeptide receptor 0.0629 0.0908 0.1688
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0054 0.1188
Brugia malayi Tachykinin-like peptides receptor 99D 0.0629 0.0908 0.9011
Schistosoma mansoni hypothetical protein 0.0259 0.0358 0.0663
Echinococcus granulosus serotonin receptor 0.0629 0.0908 0.1688
Brugia malayi topoisomerase 0.0031 0.0019 0.0175
Echinococcus granulosus Ankyrin 0.0032 0.002 0.0035
Schistosoma mansoni chromobox protein 0.009 0.0106 0.0195
Brugia malayi Thioredoxin reductase 0.0088 0.0104 0.102
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0051 0.0491
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0509 0.0729 0.1355
Schistosoma mansoni biogenic amine (5HT) receptor 0.0629 0.0908 0.1688
Schistosoma mansoni cpg binding protein 0.0068 0.0075 0.0136
Loa Loa (eye worm) melatonin receptor type 1A 0.0629 0.0908 0.9012
Onchocerca volvulus 0.0466 0.0665 0.5744
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0629 0.0908 0.9012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Echinococcus granulosus chromobox protein 1 0.009 0.0106 0.0195
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0046 0.0045
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0005 0.0045
Onchocerca volvulus 0.0036 0.0026 0.0143
Echinococcus granulosus dnaJ subfamily B 0.049 0.0702 0.1304
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.001 0.0084
Onchocerca volvulus 0.0466 0.0665 0.5744
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0123 0.0227
Plasmodium falciparum importin beta, putative 0.0061 0.0064 0.5903
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0046 0.0083
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0059 0.0061 0.0449
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0153 0.2074
Brugia malayi Doublecortin family protein 0.0069 0.0076 0.0741
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0051 0.0049
Brugia malayi Cytochrome P450 family protein 0.0032 0.0021 0.0193
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0038 0.0362
Brugia malayi RE15519p 0.0629 0.0908 0.9011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.0444 1
Loa Loa (eye worm) helicase 0.0025 0.0011 0.0105
Echinococcus multilocularis receptor type guanylyl cyclase 0.0173 0.0231 0.023
Echinococcus granulosus sterol regulatory element binding protein 0.0219 0.0299 0.0555
Echinococcus multilocularis RUN 0.0069 0.0076 0.0075
Echinococcus multilocularis g protein coupled receptor 0.0629 0.0908 0.0907
Brugia malayi nuclear receptor RXR 0.0025 0.001 0.0084
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0018 0.1412
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0054 0.4287
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0026 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Schistosoma mansoni chromobox protein 0.009 0.0106 0.0195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0629 0.0908 0.0907
Echinococcus multilocularis glutamate receptor 2 0.0336 0.0473 0.0472
Echinococcus multilocularis neuropeptide Y receptor 0.0629 0.0908 0.0907
Schistosoma mansoni glutamate receptor NMDA 0.2604 0.3844 0.7151
Plasmodium vivax glutathione reductase, putative 0.0088 0.0104 0.8408
Plasmodium vivax acyl-CoA synthetase, putative 0.009 0.0107 0.8707
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0466 0.0665 0.578
Loa Loa (eye worm) hypothetical protein 0.0253 0.0349 0.346
Onchocerca volvulus 0.0466 0.0665 0.5744
Echinococcus granulosus biogenic amine 5HT receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0064 0.3811
Chlamydia trachomatis glutamine binding protein 0.0862 0.1254 1
Onchocerca volvulus 0.0629 0.0908 0.7874
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0087
Leishmania major GTP-binding protein, putative 0.0045 0.004 0.0876
Schistosoma mansoni coup transcription factor 0.0052 0.0051 0.0092
Schistosoma mansoni tyrosine kinase 0.0058 0.0059 0.0108
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.0036 0.0027 0.0207
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0193 0.026 0.0259
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni amine GPCR 0.0629 0.0908 0.1688
Schistosoma mansoni inositol transporter 0.0042 0.0036 0.0065
Onchocerca volvulus 0.0629 0.0908 0.7874
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0051 0.0092
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0039 0.0338
Giardia lamblia Hypothetical protein 0.0036 0.0027 0.0512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Brugia malayi hypothetical protein 0.0035 0.0025 0.0237
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.001 0.0016
Mycobacterium ulcerans hypothetical protein 0.0167 0.0221 0.1755
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.0036 0.0027 0.0207
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0629 0.0908 0.0907
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0014 0.0128
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0079 0.0091 0.0711
Echinococcus granulosus RUN 0.0069 0.0076 0.0139
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0192
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0003
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.0036 0.0027 0.0587
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0026 0.0612
Loa Loa (eye worm) TK/EGFR protein kinase 0.0058 0.0059 0.0585
Echinococcus granulosus Chromobox protein 3 0.0025 0.0011 0.0017
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0007 0.0006
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.011 0.0137 0.307
Loa Loa (eye worm) hypothetical protein 0.037 0.0522 0.5184
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.004 0.0764
Schistosoma mansoni hypothetical protein 0.0036 0.0027 0.0048
Onchocerca volvulus 0.0629 0.0908 0.7874
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0153 0.1211
Loa Loa (eye worm) hypothetical protein 0.009 0.0107 0.1067
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0018 0.0086
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.0019 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.0041
Brugia malayi Nuclear hormone receptor E75 0.0025 0.001 0.0084
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Onchocerca volvulus 0.0629 0.0908 0.7874
Schistosoma mansoni lamin 0.0056 0.0056 0.0102
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0008 0.0052
Schistosoma mansoni ATP-binding cassette transporter 0.0336 0.0473 0.0878
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.01 0.079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0051 0.0491
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0035 0.0063
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0629 0.0908 0.9011
Echinococcus granulosus Niemann Pick C1 protein 0.0731 0.1059 0.1969
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0629 0.0908 0.1688
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.001 0.0016
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0003
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0036 0.0026 0.0197
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0018 0.0389
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0027 0.0355
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.0026 0.0612
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.011 0.0137 0.0253
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0245 0.0454
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.0036 0.0027 0.0654
Schistosoma mansoni nuclear hormone receptor 0.0025 0.001 0.0016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0007
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.001 0.0068
Schistosoma mansoni hypothetical protein 0.0031 0.002 0.0035
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0003
Onchocerca volvulus 0.0629 0.0908 0.7874
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0192 0.0355
Onchocerca volvulus 0.0031 0.0019 0.0084
Schistosoma mansoni glutamate receptor NMDA 0.0336 0.0473 0.0878
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0061 0.0525
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0008 0.0052
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0509 0.0729 0.1355
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0011 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0047 0.0403
Echinococcus granulosus tyrosine kinase 0.0173 0.0231 0.0427
Schistosoma mansoni hypothetical protein 0.0069 0.0076 0.0139
Giardia lamblia Replication factor C, subunit 1 0.0031 0.0019 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Onchocerca volvulus 0.0629 0.0908 0.7874
Loa Loa (eye worm) hypothetical protein 0.0036 0.0027 0.0269
Brugia malayi Glutamate receptor 2 precursor 0.0336 0.0473 0.4688
Loa Loa (eye worm) phosphatidylinositol 3 0.011 0.0137 0.1361
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0299 0.2598
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0043 0.0038 0.2211
Loa Loa (eye worm) patched family protein 0.0031 0.0019 0.0191
Brugia malayi PXA domain containing protein 0.0021 0.0005 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.002 0.0185
Echinococcus granulosus lamin 0.0056 0.0056 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0629 0.0908 0.0907
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0034
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0005 0.0003
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0036 0.0026 0.0197
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0121 0.0222
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0103 0.0126 0.17
Echinococcus multilocularis NMDA receptor 0.0336 0.0473 0.0472
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0018 0.0389
Brugia malayi protein C24B5.3 0.0031 0.0019 0.0179
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0036 0.0027 0.0048
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0018 0.0339
Echinococcus granulosus nuclear factor of activated T cells 5 0.0161 0.0212 0.0393
Echinococcus granulosus expressed conserved protein 0.048 0.0687 0.1276
Brugia malayi nuclear receptor NHR-67 0.0025 0.001 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0139
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.003 0.0028
Onchocerca volvulus 0.0031 0.0019 0.0084
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.009
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0104 0.2319
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0046
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0173 0.0231 0.1939
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.0036 0.0027 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0021 0.0205
Brugia malayi Protein kinase domain containing protein 0.0031 0.002 0.0185
Leishmania major hypothetical protein, conserved 0.0054 0.0054 0.1182
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0005 0.0045
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0018 0.0017
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0038 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Schistosoma mansoni nuclear receptor 0.0025 0.001 0.0016
Entamoeba histolytica rodhanase-like domain containing protein 0.0466 0.0665 0.907
Entamoeba histolytica rodhanase-like domain containing protein 0.0036 0.0027 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0109 0.0946
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0096 0.0945
Onchocerca volvulus 0.0036 0.0026 0.0143
Brugia malayi Latrophilin receptor protein 2 0.0117 0.0147 0.1448
Brugia malayi Rhodanese-like domain containing protein 0.0036 0.0027 0.0258
Trypanosoma cruzi As/Sb Reductase, putative 0.0036 0.0027 0.0587
Loa Loa (eye worm) hypothetical protein 0.0069 0.0076 0.0754
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0036 0.0026 0.0197
Schistosoma mansoni rab6-interacting 0.0069 0.0076 0.0139
Schistosoma mansoni loxhd1 0.0069 0.0076 0.0139
Plasmodium vivax importin-beta 2, putative 0.0061 0.0064 0.514
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0466 0.0665 0.0664
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.011 0.0137 0.0136
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0629 0.0908 0.0907
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0026 0.0559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.007 0.0606
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0028 0.0015 0.0305
Trichomonas vaginalis chromobox protein, putative 0.009 0.0106 0.0919
Toxoplasma gondii patched family protein 0.0031 0.0019 0.1094
Loa Loa (eye worm) hypothetical protein 0.0056 0.0056 0.0558
Schistosoma mansoni hypothetical protein 0.0652 0.0943 0.1752
Mycobacterium tuberculosis Conserved protein 0.0036 0.0027 0.0207
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0121 0.0222
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.037 0.0522 0.5179
Brugia malayi hypothetical protein 0.0025 0.001 0.0084
Echinococcus multilocularis GPCR, family 2 0.0117 0.0147 0.0146
Trypanosoma brucei trypanothione reductase 0.0088 0.0104 0.2319
Echinococcus granulosus heat shock protein 67b2 0.0036 0.0027 0.0048
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0036 0.0027 0.0048
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0201 0.0271 0.2156
Loa Loa (eye worm) hypothetical protein 0.0429 0.0611 0.6064
Schistosoma mansoni tar DNA-binding protein 0.0204 0.0276 0.0512
Echinococcus multilocularis tumor protein p63 0.0354 0.05 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0047 0.0403
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Echinococcus multilocularis serotonin receptor 0.0629 0.0908 0.0907
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.001 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Echinococcus multilocularis Niemann Pick C1 protein 0.0511 0.0733 0.0732
Echinococcus multilocularis sterol regulatory element binding protein 0.0219 0.0299 0.0298
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0629 0.0908 0.7874
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0026 0.0197
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0056 0.0547
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0026 0.0246
Loa Loa (eye worm) latrophilin receptor protein 2 0.0117 0.0147 0.1458
Loa Loa (eye worm) hypothetical protein 0.0055 0.0055 0.0543
Entamoeba histolytica hypothetical protein 0.0043 0.0038 0.0496
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0148
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0026 0.0257
Schistosoma mansoni hypothetical protein 0.0629 0.0908 0.1688
Echinococcus granulosus Polycystic kidney disease protein 0.0069 0.0076 0.0139
Toxoplasma gondii thioredoxin reductase 0.0088 0.0104 0.6235
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0629 0.0908 0.0907
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0026 0.1502
Schistosoma mansoni hypothetical protein 0.0212 0.0287 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0644
Loa Loa (eye worm) neuropeptide F receptor 0.0629 0.0908 0.9012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0035
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0056 0.0558
Loa Loa (eye worm) hypothetical protein 0.0079 0.0091 0.09
Mycobacterium ulcerans hypothetical protein 0.0025 0.001 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0027 0.0232
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0006
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0019 0.0159
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0064 0.1417
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0021 0.044
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Echinococcus granulosus importin subunit beta 1 0.0061 0.0064 0.0117
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0153 0.3428
Onchocerca volvulus 0.0052 0.005 0.0356
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Entamoeba histolytica hypothetical protein 0.0036 0.0027 0.0355
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0026 0.0221
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0466 0.0665 0.578
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0192
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0018 0.0138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0629 0.0908 0.0907
Echinococcus multilocularis lipoxygenase domain containing protein 0.0069 0.0076 0.0075
Brugia malayi hypothetical protein 0.0028 0.0014 0.0128
Entamoeba histolytica rodhanase-like domain containing protein 0.0466 0.0665 0.907
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0016 0.0028
Leishmania major extracellular receptor, putative 0.0172 0.0229 0.5154
Loa Loa (eye worm) G-protein coupled receptor 0.0629 0.0908 0.9012
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0862 0.1254 1
Trichomonas vaginalis cdc25b, putative 0.0466 0.0665 0.578
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0043 0.0038 0.082
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0018 0.1047
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Loa Loa (eye worm) hypothetical protein 0.009 0.0107 0.1067
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0051 0.0092
Onchocerca volvulus 0.0065 0.0069 0.0521
Echinococcus granulosus tm gpcr rhodopsin 0.1799 0.2647 0.4923
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.001 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0046 0.0083
Onchocerca volvulus 0.0629 0.0908 0.7874
Echinococcus granulosus Rhodanese 0.0036 0.0027 0.0048
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.011 0.0137 0.135
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0159
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0079 0.0091 0.0711
Brugia malayi Dopamine receptor protein 1 0.0629 0.0908 0.9011
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.001 0.0096
Entamoeba histolytica hypothetical protein 0.0103 0.0126 0.17
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0336 0.0473 0.0878
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0153 0.1211
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0034
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0128
Leishmania major As/Sb Reductase 0.0036 0.0027 0.0587
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Echinococcus granulosus tachykinin peptides receptor 99D 0.0629 0.0908 0.1688
Brugia malayi hypothetical protein 0.0259 0.0358 0.3542
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0153 0.1508
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0644
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0259 0.0358 0.0356
Mycobacterium ulcerans fatty-acid-CoA ligase 0.009 0.0107 0.0848
Onchocerca volvulus 0.0036 0.0027 0.0154
Echinococcus granulosus chromobox protein 1 0.009 0.0106 0.0195
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0026 0.0197
Mycobacterium ulcerans acetyl-CoA synthetase 0.0036 0.0026 0.0197
Loa Loa (eye worm) hypothetical protein 0.0101 0.0123 0.1224
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.001 0.0016
Echinococcus granulosus glutamate receptor 2 0.0172 0.0229 0.0425
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0146
Brugia malayi hypothetical protein 0.0031 0.0019 0.0179
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0011 0.0768
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0159
Onchocerca volvulus 0.0629 0.0908 0.7874
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Schistosoma mansoni intermediate filament proteins 0.0056 0.0056 0.0102
Loa Loa (eye worm) hypothetical protein 0.0036 0.0026 0.0257
Echinococcus granulosus 7tm_1 domain containing protein 0.0629 0.0908 0.1688
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0063 0.0115
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.011 0.0137 0.307
Onchocerca volvulus 0.0629 0.0908 0.7874
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.0036 0.0027 0.0207
Loa Loa (eye worm) RGC/RGC protein kinase 0.0173 0.0231 0.2291
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0036 0.0027 0.0232
Brugia malayi nuclear receptor NHR-88 0.0052 0.0051 0.0491
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0046 0.0444
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0018 0.0389
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0054 0.1182
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.0036 0.0027 0.0512
Giardia lamblia Thiosulfate sulfurtransferase 0.0036 0.0027 0.0512
Echinococcus granulosus tm gpcr rhodopsin 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus atrial natriuretic peptide receptor 0.0172 0.0229 0.0425
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.0019 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0018 0.0389
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0039 0.0861
Leishmania major phosphatidylinositol kinase related protein, putative 0.0025 0.001 0.0202
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0026 0.1502
Brugia malayi Nuclear hormone receptor E75 0.0025 0.001 0.0084
Brugia malayi latrophilin 2 splice variant baaae 0.0253 0.0349 0.3452
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0008 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Trichomonas vaginalis importin beta-1, putative 0.005 0.0047 0.0402
Entamoeba histolytica hypothetical protein 0.0036 0.0027 0.0355
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0153 0.3428
Loa Loa (eye worm) hypothetical protein 0.0121 0.0153 0.1518
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0201 0.0271 0.2156
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.011 0.0137 0.307
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0629 0.0908 0.1688
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0511 0.0733 1
Echinococcus granulosus tar DNA binding protein 0.0204 0.0276 0.0512
Brugia malayi hypothetical protein 0.0021 0.0005 0.0034
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0014 0.0013
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.001 0.0096
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0629 0.0908 0.0907
Schistosoma mansoni glutamate receptor kainate 0.0336 0.0473 0.0878
Schistosoma mansoni opsin-like receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0186
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0014 0.0128
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0026 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0063 0.0115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0021 0.0175
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0629 0.0908 0.9011
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0153 0.1211
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0034 0.0446
Schistosoma mansoni lipoxygenase 0.0069 0.0076 0.0139
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0023 0.05
Brugia malayi Patched related family protein 12 0.0031 0.0019 0.0179
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0011 0.0017
Brugia malayi hypothetical protein 0.0031 0.0019 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0082 0.0706
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.004 0.0039
Schistosoma mansoni amine GPCR 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Treponema pallidum DNA ligase (lig) 0.0031 0.0019 0.014
Echinococcus multilocularis Polycystic kidney disease protein 0.0069 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus sodium:glucose cotransporter 0.0042 0.0036 0.0065
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Brugia malayi ecdysteroid receptor 0.0052 0.0051 0.0491
Schistosoma mansoni glutamate receptor AMPA 0.0336 0.0473 0.0878
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.0036 0.0027 0.0207
Brugia malayi Metabotropic glutamate receptor precursor. 0.0172 0.0229 0.2267
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0101 0.0123 0.0122
Brugia malayi hypothetical protein 0.0031 0.0019 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0015 0.0123
Leishmania major phosphatidylinositol 3-kinase, putative 0.005 0.0047 0.1031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0141 0.0182 0.0337
Onchocerca volvulus 0.0124 0.0158 0.1301
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0036 0.0027 0.0232
Schistosoma mansoni opsin-like receptor 0.0629 0.0908 0.1688
Brugia malayi ORL1-like opioid receptor 0.0629 0.0908 0.9011
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.0036 0.0027 0.0587
Schistosoma mansoni metabotropic glutamate receptor 0.0172 0.0229 0.0425
Brugia malayi G protein-coupled receptor 0.0629 0.0908 0.9011
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0137 0.1188
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0629 0.0908 0.9011
Brugia malayi Protein kinase domain containing protein 0.007 0.0077 0.0758
Brugia malayi hypothetical protein 0.0134 0.0173 0.1707
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0054 0.4924
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0047 0.1029
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Echinococcus multilocularis insulin receptor 0.0127 0.0162 0.0161
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0063 0.0494
Onchocerca volvulus 0.0124 0.0158 0.1301
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Brugia malayi larval opioid receptor 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Brugia malayi CHD4 protein 0.0029 0.0016 0.0147
Echinococcus granulosus dro:myosuppressin receptor 0.0629 0.0908 0.1688
Schistosoma mansoni hypothetical protein 0.0036 0.0027 0.0048
Plasmodium falciparum acyl-CoA synthetase 0.009 0.0107 1
Brugia malayi Importin beta-1 subunit 0.0061 0.0064 0.0624
Loa Loa (eye worm) acetyltransferase 0.0151 0.0198 0.1968
Echinococcus multilocularis glutamate receptor NMDA 0.2096 0.3088 0.3087
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0629 0.0908 0.0907
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0153 0.1508
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0317 0.0444 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Loa Loa (eye worm) hypothetical protein 0.0052 0.005 0.0498
Echinococcus multilocularis expressed conserved protein 0.048 0.0687 0.0686
Onchocerca volvulus 0.0031 0.0019 0.0084
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0629 0.0908 0.1688
Entamoeba histolytica rodhanase-like domain containing protein 0.0036 0.0027 0.0355
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0006
Toxoplasma gondii patched family protein 0.0031 0.0019 0.1094
Echinococcus multilocularis cpg binding protein 0.0068 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.0121 0.0153 0.1518
Brugia malayi Serotonin receptor 0.0629 0.0908 0.9011
Entamoeba histolytica Ran family GTPase 0.0045 0.004 0.053
Echinococcus multilocularis neuropeptide receptor A26 0.1118 0.1635 0.1634
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.001 0.0016
Schistosoma mansoni hypothetical protein 0.0057 0.0058 0.0106
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.0019 0.1068
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0629 0.0908 0.0907
Echinococcus granulosus tm gpcr rhodopsin 0.0629 0.0908 0.1688
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0065 0.007 0.0069
Onchocerca volvulus Netrin receptor homolog 0.0031 0.002 0.0089
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0139
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0172 0.0229 0.2267
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0046 0.0083
Onchocerca volvulus 0.0036 0.0026 0.0143
Brugia malayi sulfakinin receptor protein 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0466 0.0665 0.66
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.011 0.0137 0.1857
Loa Loa (eye worm) oxidoreductase 0.0036 0.0026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Echinococcus granulosus serine protein kinase ATM 0.0043 0.0038 0.0068
Schistosoma mansoni neuropeptide F-like receptor 0.0629 0.0908 0.1688
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.001 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Onchocerca volvulus Protein patched homolog 0.0031 0.0019 0.0084
Schistosoma mansoni alpha-1 adrenergic receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1799 0.2647 0.2646
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0054 0.1182
Schistosoma mansoni hypothetical protein 0.0036 0.0027 0.0048
Loa Loa (eye worm) RecQ helicase 0.0023 0.0007 0.0068
Brugia malayi hypothetical protein 0.0031 0.0019 0.0175
Brugia malayi putative neuropeptide receptor 0.0629 0.0908 0.9011
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0019 0.0397
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0051 0.0092
Brugia malayi Serotonin receptor 0.0629 0.0908 0.9011
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0223 0.0305 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0069 0.0076 0.0139
Loa Loa (eye worm) hypothetical protein 0.0173 0.0231 0.2291
Brugia malayi MoeZ/MoeB domain containing protein 0.0036 0.0027 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0075 0.0645
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0051 0.0502
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0011 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0058 0.0059 0.0058
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0128
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0079 0.0091 0.0785
Echinococcus multilocularis fmrfamide receptor 0.0629 0.0908 0.0907
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.0026 0.0559
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Schistosoma mansoni tyrosine kinase 0.0058 0.0059 0.0108
Echinococcus multilocularis neuropeptide s receptor 0.1118 0.1635 0.1634
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0629 0.0908 0.1688
Schistosoma mansoni transcription factor LCR-F1 0.0259 0.0358 0.0663
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0127 0.0162 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0056 0.0482
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0051 0.0092
Trypanosoma cruzi As/Sb Reductase, putative 0.0036 0.0027 0.0587
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0161 0.0212 0.0211
Entamoeba histolytica hypothetical protein 0.0036 0.0027 0.0355
Schistosoma mansoni biogenic amine receptor 0.0629 0.0908 0.1688
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0006 0.0052
Schistosoma mansoni lipoxygenase 0.0193 0.026 0.0483
Echinococcus multilocularis orexin receptor type 2 0.0629 0.0908 0.0907
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0131
Loa Loa (eye worm) hypothetical protein 0.0079 0.0091 0.09
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.0019 0.0397
Echinococcus granulosus bloom syndrome protein 0.0023 0.0007 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0189
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0018 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0027 0.0232
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0052
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0862 0.1254 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0008 0.0618
Loa Loa (eye worm) RGC/RGC protein kinase 0.0173 0.0231 0.2291
Brugia malayi tailless protein 0.0025 0.001 0.0084
Onchocerca volvulus 0.0629 0.0908 0.7874
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.01 0.079
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0629 0.0908 0.1688
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Plasmodium falciparum LCCL domain-containing protein 0.0069 0.0076 0.7015
Onchocerca volvulus 0.0034 0.0023 0.012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0051 0.0092
Loa Loa (eye worm) doublecortin family protein 0.0069 0.0076 0.0752
Loa Loa (eye worm) hypothetical protein 0.0121 0.0153 0.1518
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.011 0.0137 0.307
Echinococcus multilocularis nmda type glutamate receptor 0.3294 0.4869 0.4868
Giardia lamblia Hypothetical protein 0.0036 0.0027 0.0512
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Schistosoma mansoni topbp1 0.0031 0.0019 0.0033
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0003 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0204 0.0276 0.0512
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0018 0.0389
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0466 0.0665 0.578
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0051 0.0092
Entamoeba histolytica rodhanase-like domain containing protein 0.0466 0.0665 0.907
Loa Loa (eye worm) glutathione reductase 0.0088 0.0104 0.1031
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0005 0.0003
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0079 0.0091 0.0785
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0629 0.0908 0.1688
Schistosoma mansoni fkbp-rapamycin associated protein 0.0028 0.0015 0.0025
Brugia malayi Dopamine receptor protein 2 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0128
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0058 0.0059 0.0108
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0466 0.0665 0.1235
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.0026 0.2026
Mycobacterium tuberculosis Probable dehydrogenase 0.0201 0.0271 0.2156
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0026 0.0197
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.0019 0.0175
Echinococcus granulosus rhodopsin orphan GPCR 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.0056 0.0056 0.0555
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0047 0.0403
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0629 0.0908 0.1688
Loa Loa (eye worm) hypothetical protein 0.009 0.0107 0.1067
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.004 0.3648
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0005 0.0045
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0039 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0047 0.0403
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0051 0.0359
Echinococcus granulosus geminin 0.0695 0.1006 0.187
Schistosoma mansoni hypothetical protein 0.0253 0.0349 0.0646
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0026 0.0559
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.005 0.0047 0.0046
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0008 0.0538
Schistosoma mansoni hypothetical protein 0.0629 0.0908 0.1688
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0223 0.0305 0.2421
Leishmania major importin beta-1 subunit, putative 0.005 0.0047 0.1029
Echinococcus granulosus lipoxygenase domain containing protein 0.0069 0.0076 0.0139
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0032 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0051 0.0491
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0005 0.0006
Entamoeba histolytica rodhanase-like domain containing protein 0.0036 0.0027 0.0355
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.0019 0.1654
Echinococcus granulosus sex peptide receptor 0.0629 0.0908 0.1688
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0397
Loa Loa (eye worm) glutamate receptor 2 0.0336 0.0473 0.4694
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Echinococcus granulosus tumor protein p63 0.0354 0.05 0.0928
Loa Loa (eye worm) hypothetical protein 0.0269 0.0373 0.3698
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.001 0.0016
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.0036 0.0027 0.0587
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0196 0.4399
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0629 0.0908 0.1688
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.0026 0.0338
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Plasmodium vivax multidomain scavenger receptor, putative 0.0069 0.0076 0.6107
Brugia malayi hypothetical protein 0.0039 0.0031 0.03
Brugia malayi ecdysone receptor 0.0025 0.001 0.0084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0046 0.0083
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0509 0.0729 0.1355
Leishmania major protein kinase, putative 0.0019 0.0001 0.0003
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Brugia malayi hypothetical protein 0.0069 0.0076 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0165
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0026 0.0221
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0116
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0032 0.0276
Mycobacterium ulcerans hypothetical protein 0.0036 0.0027 0.0207
Mycobacterium tuberculosis Probable reductase 0.0201 0.0271 0.2156
Brugia malayi Patched related family protein 10 0.0031 0.0019 0.0179
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.0036 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0502
Entamoeba histolytica hypothetical protein 0.0259 0.0358 0.4871
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0019 0.0159
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.0036 0.0027 0.0654
Brugia malayi Patched family protein 0.0031 0.0019 0.0179
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0128
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0063 0.0115
Schistosoma mansoni hypothetical protein 0.0022 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0124 0.0158 0.1569
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0466 0.0665 0.578
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0397
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0018 0.0389
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0005 0.0034
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0021 0.0205
Brugia malayi Furin-like cysteine rich region family protein 0.0058 0.0059 0.0574
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Plasmodium falciparum glutathione reductase 0.0088 0.0104 0.9657
Echinococcus granulosus nmda type glutamate receptor 0.3294 0.4869 0.9059
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.001 0.0202
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0105 0.0103
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0336 0.0473 0.0878
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0063 0.0494
Echinococcus granulosus metabotropic glutamate receptor 2 0.0172 0.0229 0.0425
Onchocerca volvulus 0.0629 0.0908 0.7874
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0006
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0192
Mycobacterium ulcerans hypothetical protein 0.0121 0.0153 0.1211
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0509 0.0729 0.0728
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.005 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Entamoeba histolytica nucleoside transporter, putative 0.0079 0.0091 0.1224
Leishmania major hypothetical protein, conserved 0.0036 0.0027 0.0587
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0056 0.0056 0.0406
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0509 0.0729 0.0728
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0018 0.0389
Schistosoma mansoni chromobox protein 0.0025 0.0011 0.0017
Plasmodium falciparum lipid/sterol:H+ symporter 0.0031 0.0019 0.1695
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0028 0.0015 0.0025
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0011 0.0569
Loa Loa (eye worm) hypothetical protein 0.009 0.0107 0.1067
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.005 0.0047 0.0085
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0026 0.0559
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0047 0.0403
Loa Loa (eye worm) hypothetical protein 0.0629 0.0908 0.9012
Loa Loa (eye worm) hypothetical protein 0.0172 0.0229 0.2276
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0063 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0102 0.0885
Onchocerca volvulus 0.0629 0.0908 0.7874
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.003 0.0294
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0027 0.0232
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0013 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0063 0.0494
Schistosoma mansoni amine GPCR 0.0629 0.0908 0.1688
Brugia malayi nuclear hormone receptor 0.0052 0.0051 0.0491
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0038 0.3425
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0042 0.0036 0.0035
Onchocerca volvulus 0.0036 0.0027 0.0154
Loa Loa (eye worm) hypothetical protein 0.035 0.0494 0.4902
Brugia malayi hypothetical protein 0.0031 0.0019 0.0179
Schistosoma mansoni importin beta-1 0.0061 0.0064 0.0117
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.0221 0.1755
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0201 0.0271 0.8879
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0028 0.0015 0.0185
Loa Loa (eye worm) RNA binding protein 0.0204 0.0276 0.2742
Schistosoma mansoni hypothetical protein 0.0117 0.0147 0.0271
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0045
Schistosoma mansoni hypothetical protein 0.0336 0.0473 0.0878
Echinococcus multilocularis sex peptide receptor 0.0629 0.0908 0.0907
Echinococcus granulosus biogenic amine 5HT receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis thyroid hormone receptor alpha 0.0183 0.0245 0.0244
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0031 0.0019 0.1109
Echinococcus granulosus glutamate NMDA receptor subunit 0.0336 0.0473 0.0878
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0137 0.1188
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0026 0.0559
Schistosoma mansoni DNA ligase IV 0.0031 0.0019 0.0033
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0026 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0087
Brugia malayi hypothetical protein 0.0629 0.0908 0.9011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0026 0.0197
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0027 0.0232
Onchocerca volvulus 0.0792 0.115 1
Echinococcus multilocularis Rhodanese 0.0036 0.0027 0.0026
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0026 0.0197
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.004 0.3176
Echinococcus granulosus neuropeptide Y receptor 0.0629 0.0908 0.1688
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0005 0.0003
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.0036 0.0027 0.0048
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0036 0.0027 0.0587
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0011 0.0087

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Compound was evaluated for ventricular tachycardia activity in perorally administered mice, 30 min before aconitine infusion, at a dose of 10 mg/kg; S=significant antiarrhythmic effect ChEMBL. 6147415
Activity (functional) Compound was evaluated for ventricular extrasystole activity, 3 min before aconitine infusion, at a dose of 3 mg/kg, intravenously administered in mice; S=significant antiarrhythmic effect ChEMBL. 6147415
Activity (functional) Compound was evaluated for ventricular tachycardia activity in intravenously administered mice, 3 min before aconitine infusion, at a dose of 3 mg/kg; S=significant antiarrhythmic effect ChEMBL. 6147415
Kd (binding) = 4.46 Beta adrenergic receptor blocking activity measured by the chronotropic effect was determined 1 hr after pretreatment of the right atria in guinea pig ChEMBL. 6147415
Kd (binding) = 5.19 Beta adrenergic receptor blocking activity measured by the inotropic effect was determined 1 hr after pretreament of the right atria in guinea pig ChEMBL. 6147415

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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