Detailed information for compound 1600718

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 441.563 | Formula: C18H20FN3O3S3
  • H donors: 0 H acceptors: 3 LogP: 5.57 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(OC(=O)CSc1sc2c(n1)cc(c(c2)F)n1nc(sc1=O)C(C)(C)C)C
  • InChi: 1S/C18H20FN3O3S3/c1-9(2)25-14(23)8-26-16-20-11-7-12(10(19)6-13(11)27-16)22-17(24)28-15(21-22)18(3,4)5/h6-7,9H,8H2,1-5H3
  • InChiKey: WEGUJSFAXMHLLX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protoporphyrinogen oxidase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus protoporphyrinogen oxidase Get druggable targets OG5_129066 All targets in OG5_129066
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) Get druggable targets OG5_129066 All targets in OG5_129066
Schistosoma japonicum ko:K00231 protoporphyrinogen oxidase [EC1.3.3.4B], putative Get druggable targets OG5_129066 All targets in OG5_129066
Mycobacterium tuberculosis Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) Get druggable targets OG5_129066 All targets in OG5_129066
Candida albicans protoporphyrinogen oxidase Get druggable targets OG5_129066 All targets in OG5_129066
Echinococcus multilocularis protoporphyrinogen oxidase Get druggable targets OG5_129066 All targets in OG5_129066
Chlamydia trachomatis protoporphyrinogen oxidase Get druggable targets OG5_129066 All targets in OG5_129066
Mycobacterium ulcerans protoporphyrinogen oxidase Get druggable targets OG5_129066 All targets in OG5_129066
Candida albicans protoporphyrinogen oxidase, heme biosynthesis Get druggable targets OG5_129066 All targets in OG5_129066
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor Get druggable targets OG5_129066 All targets in OG5_129066
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0108 0.0349 0.7411
Brugia malayi hypothetical protein 0.0027 0.0067 0.0428
Echinococcus multilocularis thyroid hormone receptor alpha 0.0174 0.0577 0.0577
Schistosoma mansoni neuropeptide receptor 0.0108 0.0349 0.0349
Schistosoma mansoni peptidase 0.001 0.0009 0.0009
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Onchocerca volvulus 0.0033 0.0089 0.1773
Brugia malayi hypothetical protein 0.0024 0.0057 0.0365
Onchocerca volvulus 0.0143 0.0468 1
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0153 0.0153
Loa Loa (eye worm) beta-lactamase 0.0143 0.0468 0.2987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0087 0.1367
Brugia malayi putative neuropeptide receptor 0.0108 0.0349 0.2226
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.03 0.1912
Echinococcus granulosus snurportin 1 0.0298 0.1004 0.1004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.0007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Leishmania major phosphatidylinositol 3-kinase, putative 0.0172 0.0568 0.1852
Schistosoma mansoni neuropeptide receptor 0.0108 0.0349 0.0349
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0057 0.1082
Echinococcus granulosus integrin alpha ps 0.0026 0.0066 0.0066
Echinococcus multilocularis G protein coupled receptor 139 0.2902 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0153 0.0153
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0057 0.0057
Loa Loa (eye worm) neuropeptide F receptor 0.0108 0.0349 0.2226
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0033 0.0089 0.1457
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0033 0.0089 0.0089
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0172 0.0568 0.1852
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0149 0.0149
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0007 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0132 0.0845
Toxoplasma gondii FATC domain-containing protein 0.0097 0.031 0.5447
Toxoplasma gondii ABC1 family protein 0.0143 0.0468 0.8237
Entamoeba histolytica hypothetical protein 0.0071 0.022 0.3796
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.01 0.034
Schistosoma mansoni tar DNA-binding protein 0.032 0.1079 0.1079
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0172 0.0568 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0058 0.0058
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0108 0.0349 0.2226
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0149 0.0149
Toxoplasma gondii hypothetical protein 0.0009 0.0007 0.0129
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Schistosoma mansoni neuropeptide F-like receptor 0.0108 0.0349 0.0349
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0033 0.0089 0.1567
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0149 0.0149
Brugia malayi neuropeptide F receptor 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0011 0.0011
Echinococcus multilocularis geminin 0.0347 0.1174 0.1174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 0.0349 0.0349
Schistosoma mansoni cpg binding protein 0.0031 0.0081 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0149 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0149 0.0953
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0089
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0009 0.0007 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0149 0.0953
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0097 0.031 0.5447
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0132 0.0132
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0073
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.003 0.0535
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0062 0.0397
Toxoplasma gondii ubiquitin-specific protease USP4 0.0009 0.0007 0.0129
Echinococcus granulosus smad 0.0008 0.0003 0.0003
Echinococcus multilocularis tar DNA binding protein 0.032 0.1079 0.1079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0161
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0033 0.0089 0.1457
Loa Loa (eye worm) RNA binding protein 0.032 0.1079 0.6885
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0108 0.0349 0.0349
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus bloom syndrome protein 0.0024 0.0058 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0149 0.0953
Entamoeba histolytica hypothetical protein 0.0071 0.022 0.3796
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Onchocerca volvulus 0.0094 0.03 0.6344
Echinococcus multilocularis allatostatin A receptor 0.0108 0.0349 0.0349
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0009 0.0007 0.0007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0149 0.3082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.0443 0.2824
Brugia malayi G protein-coupled receptor F59B2.13 0.0108 0.0349 0.2226
Schistosoma mansoni amine GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni amine GPCR 0.0108 0.0349 0.0349
Brugia malayi Tachykinin-like peptides receptor 99D 0.0108 0.0349 0.2226
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0033 0.0089 0.0089
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0428
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0108 0.0349 0.0349
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0011 0.0011
Mycobacterium tuberculosis Conserved protein 0.0143 0.0468 0.1497
Plasmodium falciparum protoporphyrinogen oxidase 0.0025 0.0062 0.6703
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0062 0.0975
Onchocerca volvulus 0.0051 0.0149 0.3082
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0149 0.0953
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Schistosoma mansoni ran 0.0021 0.0046 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0149 0.0953
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0149 0.0953
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0149 0.0149
Onchocerca volvulus 0.0108 0.0349 0.7411
Echinococcus multilocularis Smad4 0.0008 0.0003 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0009 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0009 0.0058
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0108 0.0348 0.612
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Entamoeba histolytica hypothetical protein 0.0033 0.0089 0.1457
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0033 0.0089 0.1457
Onchocerca volvulus 0.0108 0.0349 0.7411
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0089 0.0301
Schistosoma mansoni tar DNA-binding protein 0.032 0.1079 0.1079
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0172 0.0568 0.1852
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0132 0.0132
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.01 0.1766
Echinococcus multilocularis serotonin receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0028 0.0095
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0089 0.0568
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0149 0.0149
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.0007
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0033 0.0089 0.1457
Echinococcus granulosus Smad4 0.0008 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0349 0.0349
Echinococcus granulosus GPCR family 2 0.0047 0.0137 0.0137
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.1773
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0149 0.0953
Schistosoma mansoni ets-related 0.0222 0.0741 0.0741
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0155
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) melatonin receptor type 1A 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Brugia malayi GnHR receptor homolog 0.0108 0.0349 0.2226
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0073
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0097 0.031 0.1975
Entamoeba histolytica hypothetical protein 0.0071 0.022 0.3796
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.007 0.7725
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0132 0.2331
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0019 0.0339
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0062 0.0062
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0108 0.0349 0.0349
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0009 0.0009
Schistosoma mansoni amine GPCR 0.0108 0.0349 0.0349
Brugia malayi CXXC zinc finger family protein 0.0031 0.0081 0.0514
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0033 0.0089 0.1567
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0009 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Brugia malayi conserved hypotetical protein 0.0024 0.0057 0.0365
Brugia malayi RNA, U transporter 1 0.0079 0.0249 0.1589
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0057 0.0057
Schistosoma mansoni alpha-1 adrenergic receptor 0.0108 0.0349 0.0349
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0009 0.0009
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.01 0.1659
Plasmodium falciparum importin beta, putative 0.0028 0.0071 0.7824
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0011 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.029
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.0301
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0067 0.0428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0227 0.145
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Leishmania major phosphatidylinositol kinase, putative 0.0033 0.0089 0.029
Brugia malayi beta-lactamase family protein 0.0143 0.0468 0.2987
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0108 0.0349 0.2226
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0806
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0009 0.0007 0.0007
Echinococcus multilocularis protoporphyrinogen oxidase 0.0192 0.0638 0.0638
Brugia malayi Dopamine receptor 0.0108 0.0349 0.2226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Mycobacterium ulcerans monoamine oxidase 0.0025 0.0062 0.0974
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.0007
Toxoplasma gondii histone lysine-specific demethylase 0.0025 0.0062 0.1093
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.1457
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.0007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus granulosus neuropeptide Y receptor 0.0108 0.0349 0.0349
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0033 0.0089 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0486 0.31
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0057 0.0057
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0848 0.2905 0.2905
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi MH2 domain containing protein 0.012 0.0388 0.2476
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0025 0.0062 0.0974
Brugia malayi beta-lactamase family protein 0.0143 0.0468 0.2987
Loa Loa (eye worm) G-protein coupled receptor 0.0108 0.0349 0.2226
Echinococcus granulosus serotonin receptor 0.0108 0.0349 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni hypothetical protein 0.0347 0.1174 0.1174
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0132 0.0132
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0062 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0153 0.2588
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0108 0.0349 0.7411
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0007 0.0046
Entamoeba histolytica hypothetical protein 0.0071 0.022 0.3796
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1457
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0153 0.0497
Schistosoma mansoni hypothetical protein 0.0124 0.0403 0.0403
Echinococcus granulosus survival motor neuron protein 1 0.0461 0.1567 0.1567
Echinococcus granulosus alpha 1A adrenergic receptor 0.0108 0.0349 0.0349
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0292
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0009 0.0007 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0388 0.2476
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0011 0.0011
Echinococcus multilocularis serine protein kinase ATM 0.0097 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Onchocerca volvulus 0.0108 0.0349 0.7411
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0009 0.0224
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.0301
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0025 0.0062 0.1188
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.0007
Schistosoma mansoni DNA helicase recq5 0.001 0.0009 0.0009
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0067 0.0428
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0172 0.0568 0.1924
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0349 0.0349
Echinococcus granulosus g protein coupled receptor 0.0108 0.0349 0.0349
Mycobacterium ulcerans beta-lactamase 0.0143 0.0468 0.734
Echinococcus granulosus neuropeptides capa receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0132 0.0448
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0033 0.0089 0.0089
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Loa Loa (eye worm) Smad1 0.0008 0.0003 0.0019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0443 0.0443
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0108 0.0349 0.2226
Echinococcus multilocularis neuropeptide Y receptor 0.0108 0.0349 0.0349
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0067 0.0067
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.007 0.124
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0011 0.0011
Schistosoma mansoni ets 0.0011 0.0011 0.0011
Onchocerca volvulus 0.0108 0.0349 0.7411
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0172 0.0568 0.0568
Brugia malayi Dopamine receptor protein 1 0.0108 0.0349 0.2226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0149 0.3082
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0149 0.0149
Brugia malayi hypothetical protein 0.0025 0.0062 0.0396
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0009 0.0009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0172 0.0568 0.3626
Schistosoma mansoni hypothetical protein 0.0101 0.0324 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Entamoeba histolytica hypothetical protein 0.0033 0.0089 0.1457
Loa Loa (eye worm) RecQ helicase 0.0024 0.0058 0.037
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Mycobacterium ulcerans dehydrogenase 0.0025 0.0062 0.0974
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Brugia malayi nuclear receptor NHR-67 0.0024 0.0057 0.0365
Brugia malayi Ets-domain containing protein 0.0073 0.0227 0.145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0057 0.0057
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0057 0.0365
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Brugia malayi TAR-binding protein 0.032 0.1079 0.6885
Echinococcus multilocularis g-protein coupled receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Mycobacterium tuberculosis Conserved protein 0.0143 0.0468 0.1497
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0149 0.0953
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0028 0.0178
Schistosoma mansoni elf1 0.0011 0.0011 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0057 0.0057
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.2466 0.8493 0.8493
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0172 0.0568 0.1924
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0027 0.0069 0.1206
Brugia malayi hypothetical protein 0.0018 0.0037 0.0233
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0468 1
Echinococcus multilocularis neuropeptides capa receptor 0.0108 0.0349 0.0349
Mycobacterium ulcerans esterase/lipase LipP 0.0143 0.0468 0.734
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.0007
Brugia malayi sulfakinin receptor protein 0.0108 0.0349 0.2226
Echinococcus multilocularis beta LACTamase domain containing family member 0.0143 0.0468 0.0468
Schistosoma mansoni biogenic amine receptor 0.0108 0.0349 0.0349
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0075 0.0234 0.1491
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0025 0.0062 0.0974
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0019 0.0212
Echinococcus granulosus neuropeptide FF receptor 2 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0568
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0057 0.0057
Onchocerca volvulus 0.0108 0.0349 0.7411
Brugia malayi nuclear hormone receptor 0.0051 0.0149 0.0953
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Echinococcus granulosus neuropeptide receptor 0.0108 0.0349 0.0349
Schistosoma mansoni neuropeptide receptor 0.2902 1 1
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0089 0.1567
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0149
Brugia malayi MH2 domain containing protein 0.0008 0.0003 0.0019
Schistosoma mansoni hypothetical protein 0.0071 0.022 0.022
Echinococcus multilocularis survival motor neuron protein 1 0.0461 0.1567 0.1567
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0033 0.0089 0.0089
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.01 0.01
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0835
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Echinococcus multilocularis neuropeptides capa receptor 0.0108 0.0349 0.0349
Echinococcus granulosus 7tm_1 domain containing protein 0.0108 0.0349 0.0349
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0025
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0062 0.0211
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0009 0.0007 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.032 0.1079 0.6885
Onchocerca volvulus Huntingtin homolog 0.0119 0.0387 0.8231
Schistosoma mansoni smad 0.0008 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0149 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0149 0.0953
Mycobacterium tuberculosis Probable lipase LipE 0.0143 0.0468 0.1497
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.0815
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.0007
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0062 0.021
Onchocerca volvulus 0.0108 0.0349 0.7411
Schistosoma mansoni amine oxidase 0.0025 0.0062 0.0062
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0153 0.0516
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0349 0.0349
Brugia malayi nuclear hormone receptor 0.0024 0.0057 0.0365
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 0.0349 0.0349
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.0007
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Entamoeba histolytica hypothetical protein 0.0097 0.031 0.5388
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0403 0.0403
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0033 0.0089 0.0568
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0149 0.0953
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0007 0.0007
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0349 0.0349
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0149 0.0149
Brugia malayi hypothetical protein 0.0024 0.0057 0.0365
Schistosoma mansoni integrin alpha 0.0055 0.0164 0.0164
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0132 0.0432
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0062 0.1188
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Brugia malayi ubiquitin specific protease 14 0.0009 0.0007 0.0047
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0089 0.0285
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0108 0.0349 0.2226
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 0.0349 0.0349
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0227 0.0227
Schistosoma mansoni ets-related 0.0011 0.0011 0.0011
Schistosoma mansoni coup transcription factor 0.0051 0.0149 0.0149
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0028 0.0178
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0033 0.0089 0.0089
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0071 0.0455
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0033 0.0089 0.0089
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0108 0.0349 0.0349
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0058 0.0902
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0062 0.6703
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0172 0.0568 1
Echinococcus multilocularis sex peptide receptor 0.0108 0.0349 0.0349
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0033 0.0089 0.1457
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.0007
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0033 0.0089 0.1457
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Brugia malayi transcription factor E74 isoform 0.0011 0.0011 0.0073
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Schistosoma mansoni biogenic amine receptor 0.0108 0.0349 0.0349
Echinococcus granulosus neuropeptide s receptor 0.0108 0.0349 0.0349
Echinococcus granulosus peptide allatostatin:somatostatin 0.0108 0.0349 0.0349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0137 0.0137
Echinococcus granulosus serine protein kinase ATM 0.0097 0.031 0.031
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0062 0.0062
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0008 0.0048
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0089 0.0568
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Brugia malayi Smad1 0.0008 0.0003 0.0019
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0108 0.0349 0.2226
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0047
Brugia malayi Serotonin receptor 0.0108 0.0349 0.2226
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0019 0.0063
Brugia malayi G-protein coupled receptor 0.0108 0.0349 0.2226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0149 0.0953
Loa Loa (eye worm) hypothetical protein 0.0064 0.0195 0.1247
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0033 0.0089 0.0089
Echinococcus multilocularis GPCR, family 2 0.0047 0.0137 0.0137
Schistosoma mansoni Smad4 0.0008 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0062 0.1188
Mycobacterium tuberculosis Probable esterase LipL 0.0143 0.0468 0.1497
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0161
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1457
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0443 0.0443
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0057 0.0057
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0033 0.0089 0.0301
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1457
Schistosoma mansoni tar DNA-binding protein 0.032 0.1079 0.1079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0031 0.0515
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0155
Leishmania major hypothetical protein, conserved 0.0028 0.007 0.023
Brugia malayi hypothetical protein 0.0009 0.0007 0.0047
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0143 0.0468 0.734
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0686
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 0.0349 0.0349
Brugia malayi MH2 domain containing protein 0.0008 0.0003 0.0019
Echinococcus multilocularis smad 0.0008 0.0003 0.0003
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0033 0.0089 0.0301
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 0.0349 0.0349
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0048 0.4959
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1457
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 0.0349 0.0349
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 0.0349 0.0349
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0349 0.0349
Brugia malayi beta-lactamase 0.0143 0.0468 0.2987
Brugia malayi AKH receptor 0.0108 0.0349 0.2226
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0033 0.0089 0.1567
Brugia malayi ecdysteroid receptor 0.0051 0.0149 0.0953
Echinococcus multilocularis fmrfamide receptor 0.0108 0.0349 0.0349
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0108 0.0348 0.612
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0108 0.0349 0.0349
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0172 0.0568 0.1924
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0149 0.0953
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0153 0.0973
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.2466 0.8493 0.8493
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0686
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0149 0.0953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0172 0.0568 0.1852
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0428
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0023 0.0053 0.0815
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0388 0.2476
Echinococcus granulosus allatostatin A receptor 0.0108 0.0349 0.0349
Onchocerca volvulus 0.0108 0.0349 0.7411
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0033 0.0089 0.0089
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0172 0.0568 0.0568
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0067 0.0067
Brugia malayi Dopamine receptor protein 2 0.0108 0.0349 0.2226
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0089 0.1457
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0806
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0153 0.0516
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0121 0.0393 0.2508
Loa Loa (eye worm) fli-1 protein 0.0222 0.0741 0.473
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0143 0.0468 0.1497
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0058
Plasmodium vivax importin-beta 2, putative 0.0028 0.0071 0.1387
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Echinococcus multilocularis Zinc finger, PHD finger 0.0033 0.0089 0.0089
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0001 0.0001
Schistosoma mansoni fkbp-rapamycin associated protein 0.0097 0.031 0.031
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0097 0.031 0.031
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Trypanosoma brucei protein kinase, putative 0.0051 0.0153 0.2683
Schistosoma mansoni tar DNA-binding protein 0.032 0.1079 0.1079
Echinococcus multilocularis neuropeptide receptor A26 0.0108 0.0349 0.0349
Loa Loa (eye worm) inositol-1 0.0036 0.01 0.064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.0062 0.0199
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0003 0.0019
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0009 0.0009
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Echinococcus multilocularis 0.0025 0.0062 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0349 0.0349
Schistosoma mansoni adenoreceptor 0.0108 0.0349 0.0349
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.0301
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0149 0.0149
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.1004 0.6406
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.0007
Plasmodium vivax hypothetical protein 0.0033 0.0089 0.1773
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0073 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.007 0.124
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0057 0.0365
Schistosoma mansoni cpg binding protein 0.0032 0.0087 0.0087
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0058 0.037
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0292
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0108 0.0349 0.0349
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0009 0.0007 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.007 0.0239
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0028 0.0028
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0468 0.0468
Onchocerca volvulus 0.0108 0.0349 0.7411
Brugia malayi ecdysone receptor 0.0024 0.0057 0.0365
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0033 0.0089 0.0089
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0097 0.031 0.031
Onchocerca volvulus 0.0033 0.0089 0.1773
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0149 0.0149
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0057 0.0057
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.2319 0.2319
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0468 0.8214
Echinococcus multilocularis fmrfamide receptor 0.0108 0.0349 0.0349
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0028 0.0091
Schistosoma mansoni hypothetical protein 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0137 0.0871
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0009 0.0007 0.0129
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0057 0.0057
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0132 0.0132
Brugia malayi follicle stimulating hormone receptor 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0132 0.0132
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0033 0.0089 0.1457
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0149 0.0149
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0089 0.0568
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0033 0.0089 1
Giardia lamblia Hypothetical protein 0.0033 0.0089 0.1457
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0195 0.3352
Trypanosoma cruzi hypothetical protein, conserved 0.0862 0.2954 1
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.007 0.137
Echinococcus granulosus tachykinin peptides receptor 99D 0.0108 0.0349 0.0349
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni nuclear receptor 0.0024 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Echinococcus granulosus sex peptide receptor 0.0108 0.0349 0.0349
Brugia malayi Ets-domain containing protein 0.0011 0.0011 0.0073
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0149 0.3082
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0011 0.0011
Leishmania major importin beta-1 subunit, putative 0.0023 0.0053 0.0173
Leishmania major hypothetical protein, unknown function 0.0033 0.0089 0.029
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0108 0.0349 0.2226
Mycobacterium leprae Probable lipase LipE 0.0143 0.0468 0.734
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0443 0.0443
Schistosoma mansoni hypothetical protein 0.0108 0.0349 0.0349
Onchocerca volvulus 0.0024 0.0057 0.1082
Echinococcus granulosus protein C ets 2 0.0011 0.0011 0.0011
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0192 0.0638 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Echinococcus multilocularis 0.0033 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0428
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.0007
Echinococcus granulosus integrin alpha ps 0.0055 0.0164 0.0164
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.0443 0.2824
Brugia malayi amine oxidase, flavin-containing family protein 0.0025 0.0062 0.0396
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Trypanosoma cruzi target of rapamycin kinase 3 0.0172 0.0568 0.1924
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Brugia malayi Integrin alpha pat-2 precursor 0.0055 0.0164 0.1048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 0.0349 0.0349
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0025
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0033 0.0089 0.0089
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0033 0.0089 1
Schistosoma mansoni survival motor neuron protein 0.0094 0.03 0.03
Echinococcus granulosus g-protein coupled receptor 0.0108 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0026 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0149 0.0953
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0033 0.0089 0.1457
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.1457
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Echinococcus multilocularis orexin receptor type 2 0.0108 0.0349 0.0349
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0067 0.0428
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0018 0.0018
Schistosoma mansoni histamine h1 receptor 0.0108 0.0349 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0003 0.0003
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0149 0.0953
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0007 0.0047
Echinococcus multilocularis integrin alpha ps 0.0026 0.0066 0.0066
Mycobacterium leprae conserved hypothetical protein 0.0143 0.0468 0.734
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0349 0.0349
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0089 0.1457
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0172 0.0568 0.3626
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0064 0.0195 0.0661
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0149 0.0953
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0149 0.0953
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0172 0.0568 1
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0468 0.1585
Schistosoma mansoni hypothetical protein 0.0047 0.0137 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Schistosoma mansoni opsin-like receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Leishmania major UDP-galactopyranose mutase 0.0025 0.0062 0.0202
Echinococcus granulosus g protein coupled receptor 0.0108 0.0349 0.0349
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.0007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0062 0.021
Loa Loa (eye worm) neuropeptide F receptor 0.0108 0.0349 0.2226
Brugia malayi Inositol-1 0.0036 0.01 0.064
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0153 0.0516
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0172 0.0568 0.0568
Echinococcus granulosus neuropeptide Y receptor 0.0108 0.0349 0.0349
Echinococcus granulosus importin subunit beta 1 0.0028 0.0071 0.0071
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0153 0.0497
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0486 0.31
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0028 0.0448
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0172 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0009 0.0007 0.0007
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.2319 0.2319
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0033 0.0089 0.1457
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.0686
Brugia malayi isocitrate dehydrogenase 0.0015 0.0028 0.0178
Onchocerca volvulus Neuropeptide F receptor homolog 0.0108 0.0349 0.7411
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0066 0.0419
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Echinococcus multilocularis expressed protein 0.0009 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0298 0.1004 0.1004
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Entamoeba histolytica hypothetical protein 0.0033 0.0089 0.1457
Onchocerca volvulus Huntingtin homolog 0.0119 0.0387 0.8231
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0009 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0143 0.0468 0.734
Schistosoma mansoni tar DNA-binding protein 0.032 0.1079 0.1079
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.0348 0.6069
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0234 0.4034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0237
Loa Loa (eye worm) phosphatidylinositol kinase 0.0033 0.0089 0.0568
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0033 0.0089 0.1773
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Schistosoma mansoni integrin alpha-ps 0.0055 0.0164 0.0164
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0172 0.0568 0.0568
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0081 0.0514
Echinococcus multilocularis somatostatin receptor 0.0108 0.0349 0.0349
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0057 0.0057
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0033 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0101 0.0324 0.2068
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) G-protein coupled receptor 0.0108 0.0349 0.2226
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0009 0.0007 0.0129
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0132 0.0132
Echinococcus granulosus g protein coupled receptor 0.0108 0.0349 0.0349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0132 0.223
Entamoeba histolytica hypothetical protein 0.0033 0.0089 0.1457
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0001 0.0001
Giardia lamblia Phosphatidylinositol 4-kinase 0.0033 0.0089 0.1457
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0443 0.0443
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.1567
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0153 0.2683
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0092 0.0294 0.1878
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.0007
Leishmania major hypothetical protein, conserved 0.0143 0.0468 0.1526
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0468 0.1585
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Brugia malayi MH1 domain containing protein 0.0008 0.0003 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0132 0.0845
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trichomonas vaginalis esterase, putative 0.0143 0.0468 0.8214
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0073 0.0469
Echinococcus granulosus G protein coupled receptor 139 0.0108 0.0349 0.0349
Echinococcus granulosus neuropeptide receptor A26 0.0108 0.0349 0.0349
Brugia malayi hypothetical protein 0.0119 0.0387 0.2467
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0053 0.0815
Brugia malayi Ets-domain containing protein 0.0073 0.0227 0.145
Loa Loa (eye worm) DR-78 0.0024 0.0057 0.0365
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0149 0.0149
Brugia malayi ORL1-like opioid receptor 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0028 0.007 0.045
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0912 0.3126 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.01 0.1574
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0468 0.8214
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0003 0.0003
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0033 0.0089 0.1457
Echinococcus multilocularis ets variant gene 4 0.0011 0.0011 0.0011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0108 0.0349 0.2226
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0143 0.0468 0.1497
Echinococcus multilocularis neuropeptide Y receptor 0.0108 0.0349 0.0349
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0033 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0428
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Onchocerca volvulus 0.0025 0.0062 0.1188
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0108 0.0349 0.0349
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Onchocerca volvulus 0.0108 0.0349 0.7411
Schistosoma mansoni hypothetical protein 0.0047 0.0137 0.0137
Leishmania major phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.029
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0011 0.0073
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.01 0.1659
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0149 0.0953
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0348 0.2219
Toxoplasma gondii target of rapamycin (TOR), putative 0.0172 0.0568 1
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0033 0.0089 0.0301
Echinococcus multilocularis integrin alpha 3 0.0026 0.0066 0.0066
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0071 0.1254
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0132 0.0448
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Echinococcus multilocularis neuropeptide receptor 0.0108 0.0349 0.0349
Schistosoma mansoni inositol monophosphatase 0.0036 0.01 0.01
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0003 0.0019
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0025 0.0062 0.6703
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0033 0.0089 0.1457
Onchocerca volvulus 0.0108 0.0349 0.7411
Echinococcus granulosus beta LACTamase domain containing family member 0.0143 0.0468 0.0468
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Loa Loa (eye worm) TYRA-2 protein 0.0108 0.0349 0.2226
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0137 0.0137
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0058 0.0902
Onchocerca volvulus 0.0031 0.0081 0.1589
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0129
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0172 0.0568 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0153 0.0153
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0089 0.0568
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0046
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0009 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.022 0.022
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0149 0.0953
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0011 0.0011
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0033 0.0089 0.0089
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.0007
Brugia malayi nuclear receptor NHR-88 0.0051 0.0149 0.0953
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0132 0.223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0132 0.223
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0028 0.2526
Mycobacterium tuberculosis Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) 0.0167 0.0551 0.1761
Onchocerca volvulus 0.0108 0.0349 0.7411
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0001 0.0001
Schistosoma mansoni neuropeptide f receptor 76f 0.0108 0.0349 0.0349
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0028 0.0492
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0071 0.1254
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0192 0.0638 0.0638
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0033 0.0089 0.0089
Echinococcus granulosus tar DNA binding protein 0.032 0.1079 0.1079
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0153 0.0516
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0028 0.0089
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Mycobacterium tuberculosis Probable hydrolase 0.0143 0.0468 0.1497
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0568
Echinococcus granulosus integrin alpha 3 0.0026 0.0066 0.0066
Echinococcus granulosus ubiquitin specific peptidase c family 0.0009 0.0007 0.0007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0137 0.0871
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0028 0.0028
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0003 0.0003
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0153 0.2588
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0199 0.0199
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0009 0.0007 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.007 0.0239
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1457
Mycobacterium tuberculosis Conserved protein 0.0143 0.0468 0.1497
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0033 0.0089 0.0089
Trypanosoma brucei hypothetical protein, conserved 0.0143 0.0468 0.8237
Brugia malayi tailless protein 0.0024 0.0057 0.0365
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0057 0.0057
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0019 0.0065
Brugia malayi larval opioid receptor 0.0108 0.0349 0.2226
Schistosoma mansoni zinc finger protein 0.0024 0.0057 0.0057
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0033 0.0089 0.0089
Schistosoma mansoni opsin-like receptor 0.0108 0.0349 0.0349
Echinococcus multilocularis neuropeptide FF receptor 2 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0009 0.0007 0.0007
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0033 0.0089 0.1567
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0468 0.8214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0149 0.0149
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0057 0.0365
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0149 0.0149
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0149 0.0149
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Echinococcus granulosus geminin 0.0347 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0047 0.0137 0.0871
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0403 0.0403
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0175 0.3082
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0143 0.0468 0.2987
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0153 0.2588
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Echinococcus multilocularis neuropeptide receptor 0.2902 1 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.0007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Echinococcus granulosus dro:myosuppressin receptor 0.0108 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0108 0.0349 0.0349
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0028 0.0492
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0028 0.0492
Echinococcus granulosus neuropeptides capa receptor 0.0108 0.0349 0.0349
Schistosoma mansoni importin beta-1 0.0028 0.0071 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0108 0.0349 0.0349
Onchocerca volvulus 0.0108 0.0349 0.7411
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0033 0.0089 0.0568
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1773
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0062 0.0397
Schistosoma mansoni inositol monophosphatase 0.0036 0.01 0.01
Mycobacterium ulcerans lipase LipD 0.0143 0.0468 0.734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0025 0.0062 0.1188
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi G-protein coupled receptor 0.0108 0.0349 0.2226
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0011 0.0011
Brugia malayi RE15519p 0.0108 0.0349 0.2226
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0051 0.0149 0.0953
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0153 0.2588
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0033 0.0089 0.1457
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.01 0.1766
Mycobacterium leprae conserved hypothetical protein 0.0033 0.0089 0.1396
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0057 0.0057
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0137 0.0137
Leishmania major phosphatidylinositol kinase related protein, putative 0.0033 0.0089 0.029
Leishmania major cytochrome p450-like protein 0.0025 0.0062 0.0203
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Echinococcus multilocularis integrin alpha ps 0.0055 0.0164 0.0164
Schistosoma mansoni hypothetical protein 0.0108 0.0349 0.0349
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0071 0.0071
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0019 0.0212
Loa Loa (eye worm) integrin alpha pat-2 0.0121 0.0393 0.2507
Schistosoma mansoni hypothetical protein 0.0012 0.0018 0.0018
Onchocerca volvulus 0.0108 0.0349 0.7411
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0149 0.0953
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0011 0.0073
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.01 0.034
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0011 0.0073
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.0007
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0149 0.0149
Brugia malayi G protein-coupled receptor 0.0108 0.0349 0.2226
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0137 0.0871
Echinococcus granulosus somatostatin receptor 0.0108 0.0349 0.0349
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0137 0.0137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0097 0.031 0.1975
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0033 0.0089 0.1457
Schistosoma mansoni hypothetical protein 0.0075 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0143 0.0468 0.2987
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0097 0.031 0.1048
Leishmania major hypothetical protein, conserved 0.0896 0.3068 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0033 0.0089 0.1773
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0057 0.0057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0047 0.0137 0.0137
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0028 0.0028
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0108 0.0349 0.0349
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.01 0.0327
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0143 0.0468 0.1497
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0089 0.1567
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Schistosoma mansoni biogenic amine receptor 0.0108 0.0349 0.0349
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0028 0.0028
Echinococcus multilocularis snurportin 1 0.0298 0.1004 0.1004
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0089 0.0301
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0149 0.0149
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0062 0.1095
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Onchocerca volvulus 0.0108 0.0349 0.7411
Brugia malayi steroid hormone receptor 0.0051 0.0149 0.0953
Onchocerca volvulus 0.0143 0.0468 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0087 0.0279
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0149 0.0149
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0011 0.0011
Schistosoma mansoni opsin-like receptor 0.0108 0.0349 0.0349
Brugia malayi Cytochrome P450 family protein 0.0025 0.0062 0.0397
Onchocerca volvulus 0.0024 0.0057 0.1082
Brugia malayi nuclear receptor NHR-88 0.0024 0.0057 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0149 0.0953
Loa Loa (eye worm) hypothetical protein 0.0119 0.0387 0.2467
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0011 0.0073
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0149 0.0149
Brugia malayi Cytochrome P450 family protein 0.0025 0.0062 0.0397
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0028 0.0028
Brugia malayi Melatonin receptor type 1A 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.01 0.1659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0089 0.1457
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0033 0.0089 0.1457
Schistosoma mansoni growth hormone secretagogue receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0025 0.0062 0.0062
Schistosoma mansoni nuclear receptor 0.0024 0.0057 0.0057
Brugia malayi hypothetical protein 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0097 0.031 0.031
Brugia malayi hypothetical protein 0.0071 0.022 0.1406
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0349 0.0349
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0089 0.029
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0067 0.0067
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0009 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0149 0.0953
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.032 0.1079 0.6885
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0149 0.0953
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0001 0.0001
Echinococcus granulosus protoporphyrinogen oxidase 0.0167 0.0551 0.0551
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0324 0.2068
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0486 0.31
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.01 0.01
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0008
Schistosoma mansoni myosin xvIII 0.0108 0.0349 0.0349
Echinococcus granulosus microtubule associated protein 2 0.0679 0.2319 0.2319
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0089 0.0301
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0108 0.0349 0.2226
Brugia malayi SWIRM domain containing protein 0.0025 0.0062 0.0396
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0132 0.223
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0428
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0047
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.01 0.5
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Onchocerca volvulus 0.0143 0.0468 1
Brugia malayi Importin beta-1 subunit 0.0028 0.0071 0.0455
Schistosoma mansoni hypothetical protein 0.0047 0.0137 0.0137
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0075 0.0234 0.0234
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Echinococcus multilocularis cpg binding protein 0.0032 0.0087 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0153 0.2588
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0149 0.0149
Brugia malayi FAT domain containing protein 0.0075 0.0234 0.1491
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0153 0.0153
Mycobacterium ulcerans oxidoreductase 0.0025 0.0062 0.0974
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Onchocerca volvulus 0.0108 0.0349 0.7411
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0097 0.031 0.1048
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 0.0349 0.0349
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0033 0.0089 0.1457
Loa Loa (eye worm) TAR-binding protein 0.032 0.1079 0.6885
Loa Loa (eye worm) phosphatidylinositol 3 0.0172 0.0568 0.3626
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0149 0.0953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0172 0.0568 0.1852
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0174 0.0577 0.0577
Schistosoma mansoni integrin alpha-ps 0.0029 0.0073 0.0073
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0033 0.0089 0.0089
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0108 0.0349 0.0349
Chlamydia trachomatis protoporphyrinogen oxidase 0.0192 0.0638 0.5
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0075 0.0234 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0468 0.8214
Schistosoma mansoni hypothetical protein 0.0347 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0143 0.0468 0.2987
Echinococcus multilocularis integrin alpha ps 0.0055 0.0164 0.0164
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0028 0.0028
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0089 0.0568
Loa Loa (eye worm) hypothetical protein 0.0148 0.0486 0.31
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0033 0.0089 0.1567
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Giardia lamblia GTOR 0.0172 0.0568 1
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0192 0.0638 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0028 0.0095
Brugia malayi nuclear receptor RXR 0.0024 0.0057 0.0365
Brugia malayi RNA binding protein 0.032 0.1079 0.6885
Brugia malayi neuropeptide F receptor 0.0108 0.0349 0.2226
Brugia malayi hypothetical protein 0.0028 0.007 0.045
Echinococcus granulosus 7TM GPCR rhodopsin 0.0108 0.0349 0.0349
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0097 0.031 0.1975
Loa Loa (eye worm) hypothetical protein 0.0062 0.0191 0.1217
Loa Loa (eye worm) phosphatidylinositol 3 0.0172 0.0568 0.3626
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0172 0.0568 0.0568
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0149 0.0149
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0143 0.0468 0.1497
Echinococcus granulosus fmrfamide receptor 0.0108 0.0349 0.0349
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0092 0.0294 0.1878
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0053 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0443 0.0443
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0057 0.0365
Schistosoma mansoni amine oxidase 0.0025 0.0062 0.0062
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.01 0.1659
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0172 0.0568 0.0568
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.022 0.022
Schistosoma mansoni amine GPCR 0.0108 0.0349 0.0349
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0033 0.0089 0.0089
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0057 0.0365
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0011 0.0073
Brugia malayi hypothetical protein 0.0027 0.0067 0.0428
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0396
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0062 0.0397
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0349 0.0349
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0108 0.0349 0.0349
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.007 0.7725
Loa Loa (eye worm) hypothetical protein 0.0119 0.0387 0.2467
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0003 0.0003
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0057 0.0365
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0097 0.031 0.5388
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0024
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0057 0.0365
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.0007
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0033 0.0089 0.1567
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0057 0.0365
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0108 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0461 0.1567 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0468 0.0468
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0149 0.0149
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0349 0.0349
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0129
Brugia malayi MH1 domain containing protein 0.0008 0.0003 0.0019
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0108 0.0349 0.0349
Echinococcus granulosus cpg binding protein 0.0032 0.0087 0.0087
Brugia malayi Fli-1 protein 0.0222 0.0741 0.473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi Serotonin receptor 0.0108 0.0349 0.2226
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0009 0.0007 0.0007
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0033 0.0089 0.1457
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0153 0.2683
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0365
Echinococcus multilocularis serotonin receptor 0.0108 0.0349 0.0349
Schistosoma mansoni neuropeptide receptor 0.0108 0.0349 0.0349
Entamoeba histolytica protein kinase rad3, putative 0.0097 0.031 0.5388
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0071 0.1254
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0025 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0195 0.3352
Brugia malayi hypothetical protein 0.0461 0.1567 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.471
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0057 0.0057
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0132 0.223
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0033 0.0089 0.1567
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0149 0.0149
Schistosoma mansoni ran 0.0021 0.0046 0.0046
Schistosoma mansoni thyroid hormone receptor 0.0174 0.0577 0.0577
Brugia malayi nuclear receptor RXR 0.0027 0.0067 0.0428
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0149 0.0149
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0062 0.0211
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0468 0.8214
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0089 0.0568
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0028 0.0492
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0172 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0172 0.0568 1
Brugia malayi MAP kinase sur-1 0.0051 0.0153 0.0973
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0132 0.0132
Echinococcus multilocularis protein C ets 2 0.0011 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0094 0.03 0.03
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.004 0.004
Schistosoma mansoni DNA helicase recq1 0.001 0.0009 0.0009
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0348 0.6069
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0057 0.0057
Echinococcus multilocularis G-protein coupled receptor, putative 0.0108 0.0349 0.0349
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.022 0.022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.0815
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0172 0.0568 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 0.0349 0.0349
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0033 0.0089 0.0301
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0057 0.0057
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0057 0.0365
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0172 0.0568 0.1924
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Schistosoma mansoni gabp alpha 0.0073 0.0227 0.0227
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0089 0.1773
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0108 0.0349 0.0349
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0009 0.0007 0.0007
Echinococcus granulosus orexin receptor type 2 0.0108 0.0349 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0349 0.0349
Schistosoma mansoni cpg binding protein 0.0032 0.0087 0.0087
Schistosoma mansoni amine GPCR 0.0108 0.0349 0.0349
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0129
Loa Loa (eye worm) hypothetical protein 0.0108 0.0349 0.2226
Brugia malayi putative neuropeptide receptor NPR1 0.0108 0.0349 0.2226
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0132 0.0132
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0227 0.0227
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0033 0.0089 0.0089
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0057 0.1082
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047
Onchocerca volvulus 0.0108 0.0349 0.7411
Echinococcus granulosus hypothetical protein 0.0108 0.0349 0.0349
Echinococcus multilocularis neuropeptide s receptor 0.0108 0.0349 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.031 0.5388
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0443 0.0443
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0149 0.0149
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0047

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1.26 uM Inhibition of human PPO by capillary electrophoresis method ChEMBL. 22130420

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.