Detailed information for compound 1723264

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.505 | Formula: C24H28N4O2
  • H donors: 0 H acceptors: 2 LogP: 4.14 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(C)nc(n1)OCCCn1c2ccc(cc2c2c1CCCC2)C1=NCCO1
  • InChi: 1S/C24H28N4O2/c1-16-14-17(2)27-24(26-16)30-12-5-11-28-21-7-4-3-6-19(21)20-15-18(8-9-22(20)28)23-25-10-13-29-23/h8-9,14-15H,3-7,10-13H2,1-2H3
  • InChiKey: AWOIMEWPFPEKTG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens scavenger receptor class B, member 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Lysosome membrane protein 2, putative Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129842 All targets in OG5_129842
Schistosoma mansoni CD36-like class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) Get druggable targets OG5_129842 All targets in OG5_129842
Schistosoma mansoni CD36-like class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus lysosome membrane protein 2 Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus granulosus CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Brugia malayi CD36 family protein Get druggable targets OG5_129842 All targets in OG5_129842
Schistosoma japonicum Lysosome membrane protein 2, putative Get druggable targets OG5_129842 All targets in OG5_129842
Schistosoma japonicum Lysosome membrane protein 2, putative Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis lysosome membrane protein 2 Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Echinococcus multilocularis CD36 class B scavenger receptor Get druggable targets OG5_129842 All targets in OG5_129842
Onchocerca volvulus Lysosome membrane protein 2 homolog Get druggable targets OG5_129842 All targets in OG5_129842
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0619 0.0619
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0468 0.1923
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.145 0.3424
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0476 0.1016
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0632 0.0632
Trypanosoma brucei DNA polymerase IV, putative 0.0086 0.1023 0.2304
Loa Loa (eye worm) hypothetical protein 0.0046 0.0485 0.0761
Onchocerca volvulus 0.0089 0.1064 0.1671
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0194 0.0209
Schistosoma mansoni inositol monophosphatase 0.004 0.0395 0.0395
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0619 0.1353
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0055 0.0596 0.0936
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0308 0.0346
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0383 0.0383
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.145 0.2278
Loa Loa (eye worm) DOMON domain-containing protein 0.0071 0.0823 0.1293
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0098 0.1182 0.2678
Trypanosoma brucei metacaspase MCA3 0.0057 0.0632 0.1384
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Giardia lamblia PHD finger protein 15 0.0031 0.028 0.0575
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0504 0.0504
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0098 0.1187 0.5003
Onchocerca volvulus 0.0033 0.0302 0.0474
Entamoeba histolytica cyclin, putative 0.008 0.0947 0.111
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Echinococcus granulosus death domain containing protein 0.0014 0.0041 0.0041
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0395 0.0395
Leishmania major DNA polymerase kappa, putative 0.0064 0.0729 0.1612
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0049 0.0036
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0338 0.127
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0307 0.1231
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0342 0.0386
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0822 0.1292
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0094 0.0116
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0093 0.112 0.4285
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0504 0.0792
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0342 0.0537
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0744 0.1829
Schistosoma mansoni cyclin B 0.008 0.0947 0.0947
Loa Loa (eye worm) hypothetical protein 0.0027 0.022 0.0346
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0064 0.0729 0.1612
Loa Loa (eye worm) hypothetical protein 0.0042 0.0426 0.0669
Onchocerca volvulus 0.0021 0.0141 0.0222
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0098 0.1187 0.5003
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0042 0.0042
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0234 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0057 0.0632 0.0632
Echinococcus multilocularis lysosome membrane protein 2 0.0135 0.1694 0.1694
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0209
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0504 0.1082
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.022 0.0415
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0033 0.0308 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Echinococcus multilocularis pyruvate kinase 0.0018 0.0103 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0085 0.1006 0.1581
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0194 0.0304
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0103 0.036
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0499 0.1071
Treponema pallidum fructose-bisphosphate aldolase 0.0315 0.415 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.1422 0.2234
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.065 0.065
Schistosoma mansoni caspase-7 (C14 family) 0.0136 0.1702 0.1702
Trypanosoma cruzi DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Echinococcus granulosus pyruvate kinase 0.0018 0.0103 0.0103
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0822 0.0822
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Echinococcus granulosus chromobox protein 1 0.0075 0.0876 0.0876
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0632 0.2544
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.145 0.3309
Echinococcus multilocularis pyruvate kinase 0.0036 0.0342 0.0342
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0047 0.0074
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0395 0.0825
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0619 0.14
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0234 0.0922
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0283 0.1131
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0037 0.0349 0.0349
Toxoplasma gondii hypothetical protein 0.0025 0.0198 0.0766
Loa Loa (eye worm) hypothetical protein 0.0478 0.6365 1
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0013 0.0024 0.0024
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.022 0.0862
Mycobacterium tuberculosis Probable reductase 0.0093 0.112 0.4659
Brugia malayi MAP kinase sur-1 0.0056 0.0619 0.0972
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0632 0.0993
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0822 0.0822
Schistosoma mansoni lipoxygenase 0.006 0.0663 0.0663
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0822 0.1831
Brugia malayi Bromodomain containing protein 0.0041 0.0415 0.0651
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0619 0.0718
Schistosoma mansoni troponin I 0.0115 0.1422 0.1422
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0619 0.1353
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.145 0.1712
Entamoeba histolytica recQ family DNA helicase 0.0021 0.014 0.0145
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0613 0.1338
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0128 0.013
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0094 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0094 0.0116
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.065 0.065
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0095 0.1147 0.1802
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0135 0.1694 0.1694
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0195 0.0395
Mycobacterium ulcerans DNA polymerase IV 0.0086 0.1023 0.2557
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0413 0.0413
Brugia malayi hypothetical protein 0.0064 0.072 0.1132
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Giardia lamblia Pyruvate kinase 0.0018 0.0103 0.0144
Echinococcus granulosus pyruvate kinase 0.0036 0.0342 0.0342
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0822 0.1831
Schistosoma mansoni chromobox protein 0.0012 0.0019 0.0019
Plasmodium vivax JmjC domain containing protein 0.0027 0.022 0.0862
Chlamydia trachomatis phosphoglycerate kinase 0.0184 0.2354 1
Schistosoma mansoni hypothetical protein 0.0031 0.028 0.028
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0326 0.4293 1
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.1064 0.1671
Loa Loa (eye worm) hypothetical protein 0.008 0.0947 0.1488
Echinococcus multilocularis caspase 3 0.0078 0.0921 0.0921
Loa Loa (eye worm) hypothetical protein 0.0184 0.2354 0.3699
Schistosoma mansoni cyclin B3 0.0033 0.0308 0.0308
Echinococcus granulosus lysosomal alpha glucosidase 0.0176 0.2247 0.2247
Echinococcus granulosus troponin i 0.0115 0.1422 0.1422
Leishmania major DNA polymerase kappa, putative 0.0018 0.0094 0.0116
Trypanosoma brucei unspecified product 0.0039 0.039 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0485 0.1037
Echinococcus granulosus L aminoadipate semialdehyde 0.009 0.1074 0.1074
Schistosoma mansoni jumonji domain containing protein 0.0145 0.1832 0.1832
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0128 0.0128
Onchocerca volvulus 0.0055 0.0596 0.0936
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0395 0.0449
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0133 0.0133
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0468 0.0998
Loa Loa (eye worm) hypothetical protein 0.0085 0.1006 0.1581
Loa Loa (eye worm) hypothetical protein 0.0135 0.1694 0.2662
Entamoeba histolytica hypothetical protein 0.0021 0.0133 0.0137
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0133 0.0133
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0098 0.1187 0.1187
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0128 0.0197
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0342 0.0537
Trypanosoma brucei polo-like protein kinase 0.0103 0.1261 0.2864
Loa Loa (eye worm) hypothetical protein 0.0021 0.0141 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0395 0.1608
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.145 0.1712
Leishmania major DNA polymerase eta, putative 0.0085 0.1006 0.2265
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Echinococcus granulosus chromobox protein 2 0.0012 0.0019 0.0019
Schistosoma mansoni phd finger protein 0.0013 0.0026 0.0026
Brugia malayi jmjC domain containing protein 0.0104 0.1263 0.1985
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0619 0.0718
Trypanosoma cruzi metacaspase, putative 0.0057 0.0632 0.1384
Schistosoma mansoni hypothetical protein 0.0115 0.1422 0.1422
Schistosoma mansoni glutaminase 0.0295 0.3872 0.3872
Echinococcus granulosus oncosphere protein Tso22e 0.0143 0.18 0.18
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0822 0.0822
Entamoeba histolytica protein kinase, putative 0.0098 0.1182 0.1391
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Echinococcus multilocularis pyruvate kinase 0.0018 0.0103 0.0103
Trichomonas vaginalis cyclin B, putative 0.0033 0.0308 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Echinococcus granulosus CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0395 0.0825
Loa Loa (eye worm) hypothetical protein 0.0051 0.0547 0.086
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0504 0.1082
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0234 0.0258
Loa Loa (eye worm) hypothetical protein 0.0161 0.2048 0.3218
Mycobacterium ulcerans hypothetical protein 0.0172 0.2191 0.5609
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0094 0.0319
Echinococcus multilocularis expressed protein 0.0402 0.5341 0.5341
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0234 0.0448
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0049 0.0036
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.065 0.065
Trypanosoma cruzi ISWI complex protein 0.0016 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0302 0.0474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0141 0.0222
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.145 0.5811
Loa Loa (eye worm) DOMON domain-containing protein 0.0071 0.0823 0.1293
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0342 0.0701
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0822 0.1292
Schistosoma mansoni hypothetical protein 0.0317 0.4172 0.4172
Loa Loa (eye worm) hypothetical protein 0.0095 0.1147 0.1802
Echinococcus multilocularis cyclin b3 0.0033 0.0308 0.0308
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.1064 0.1671
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.022 0.022
Echinococcus granulosus zinc finger protein 0.0021 0.0139 0.0139
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0019 0.0019
Brugia malayi mbt repeat family protein 0.0051 0.0553 0.0869
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0195 0.0368
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0207 0.2672 0.2672
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0264 0.0264
Mycobacterium ulcerans phosphoglycerate kinase 0.0184 0.2354 0.6036
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1261 0.2864
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0209
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0553 0.0553
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0448 0.0448
Brugia malayi bZIP transcription factor family protein 0.0081 0.0958 0.1505
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0383 0.0436
Echinococcus granulosus expressed protein 0.0402 0.5341 0.5341
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0098 0.1187 0.2691
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0133 0.0133
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0155 0.0243
Schistosoma mansoni SET domain protein 0.0037 0.0349 0.0349
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0103 0.036
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0133 0.0209
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0098 0.1187 0.2691
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.022 0.0415
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0283 0.1035
Schistosoma mansoni chromobox protein 0.0075 0.0876 0.0876
Trichomonas vaginalis cyclins, putative 0.008 0.0947 0.111
Onchocerca volvulus 0.0089 0.1064 0.1671
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0383 0.0436
Brugia malayi hypothetical protein 0.0012 0.0021 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0027 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0071 0.0817 0.1284
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0504 0.1082
Loa Loa (eye worm) hypothetical protein 0.0027 0.022 0.0346
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0049 0.0012
Brugia malayi hypothetical protein 0.0021 0.0141 0.0222
Brugia malayi Protein kinase domain containing protein 0.0048 0.0504 0.0792
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0103 0.1262 0.4941
Brugia malayi fructose-bisphosphate aldolase 1 0.0098 0.1187 0.1865
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0619 0.1353
Plasmodium falciparum thioredoxin reductase 0.0041 0.0408 0.1664
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.022 0.022
Brugia malayi hypothetical protein 0.0051 0.0547 0.086
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0619 0.0619
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0283 0.1131
Loa Loa (eye worm) hypothetical protein 0.0025 0.0194 0.0304
Schistosoma mansoni hypothetical protein 0.0021 0.0141 0.0141
Echinococcus granulosus bloom syndrome protein 0.007 0.081 0.081
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0395 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.1182 0.2678
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Onchocerca volvulus 0.0257 0.3353 0.5267
Brugia malayi Cyclin, N-terminal domain containing protein 0.008 0.0947 0.1488
Entamoeba histolytica cyclin family protein 0.0033 0.0308 0.0346
Schistosoma mansoni caspase-3 (C14 family) 0.0136 0.1702 0.1702
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0094 0.0116
Echinococcus granulosus CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0744 0.3031
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0408 0.1664
Trypanosoma cruzi DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Schistosoma mansoni chromobox protein 0.0075 0.0876 0.0876
Brugia malayi Protein kinase domain containing protein 0.0098 0.1182 0.1857
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.1263 0.1263
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0283 0.0582
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0426 0.0669
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0042 0.0418 0.0657
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0184 0.2354 0.2794
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0744 0.0744
Brugia malayi DOMON domain containing protein 0.0071 0.0823 0.1293
Loa Loa (eye worm) hypothetical protein 0.0195 0.2506 0.3937
Loa Loa (eye worm) hypothetical protein 0.0089 0.1064 0.1671
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0049 0.0036
Trichomonas vaginalis cyclin B, putative 0.008 0.0947 0.111
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0822 0.1831
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0553 0.0553
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0041 0.0064
Schistosoma mansoni alpha-glucosidase 0.0151 0.1914 0.1914
Loa Loa (eye worm) hypothetical protein 0.0372 0.4925 0.7738
Trypanosoma brucei unspecified product 0.0039 0.039 0.0813
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.2928 0.46
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0013 0.0024 0.0024
Echinococcus granulosus tumor protein p63 0.0364 0.4821 0.4821
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0143 0.18 0.2827
Loa Loa (eye worm) hypothetical protein 0.009 0.1074 0.1687
Onchocerca volvulus 0.0021 0.0141 0.0222
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.0064
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0234 0.0922
Schistosoma mansoni lipoxygenase 0.0021 0.0141 0.0141
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0338 0.0659
Brugia malayi Common central domain of tyrosinase family protein 0.0089 0.1064 0.1671
Schistosoma mansoni ap endonuclease 0.002 0.0128 0.0128
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0183 0.235 0.3693
Plasmodium falciparum flap endonuclease 1 0.0028 0.0234 0.0922
Echinococcus multilocularis peregrin 0.0044 0.0455 0.0455
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0504 0.112
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0283 0.0316
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0041 0.0041
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.009 0.1074 0.1074
Brugia malayi PXA domain containing protein 0.0021 0.0133 0.0209
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0383 0.0383
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0042 0.0418 0.0418
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.1182 0.2678
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.1064 0.1671
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0234 0.0368
Schistosoma mansoni zinc finger protein 0.0021 0.0139 0.0139
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.145 0.1712
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0133 0.0133
Brugia malayi Pre-SET motif family protein 0.0226 0.2928 0.46
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0638 0.1003
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0089 0.1064 0.1671
Loa Loa (eye worm) cyclin domain-containing protein 0.0033 0.0308 0.0484
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0037 0.0349 0.0349
Brugia malayi jmjC domain containing protein 0.0027 0.022 0.0346
Loa Loa (eye worm) MBCTL1 0.0059 0.065 0.1021
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0031
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0064 0.0729 0.2964
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0619 0.1353
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0032
Trichomonas vaginalis cyclin B3, putative 0.0033 0.0308 0.0346
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0102 0.0102
Trichomonas vaginalis DNA polymerase eta, putative 0.0086 0.1023 0.1201
Loa Loa (eye worm) inositol-1 0.004 0.0395 0.062
Onchocerca volvulus 0.0064 0.072 0.1132
Echinococcus multilocularis CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Trichomonas vaginalis cyclin B, putative 0.008 0.0947 0.111
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0128 0.0466
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0383 0.0436
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Trypanosoma cruzi DNA polymerase eta, putative 0.0085 0.1006 0.2265
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0559 0.0646
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0504 0.0504
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0383 0.0798
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0033 0.0308 0.0308
Trichomonas vaginalis glutaminase, putative 0.0295 0.3872 0.461
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0141 0.0141
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Echinococcus granulosus pyruvate kinase 0.0018 0.0103 0.0103
Echinococcus granulosus dna polymerase eta 0.0085 0.1006 0.1006
Loa Loa (eye worm) hypothetical protein 0.008 0.0947 0.1488
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0093 0.112 0.4659
Onchocerca volvulus 0.0102 0.1237 0.1944
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0504 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0258 0.0286
Entamoeba histolytica hypothetical protein 0.0012 0.0019 0.00000000031556
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0264 0.0264
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1261 0.1981
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0499 0.0574
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0143 0.18 0.18
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0133 0.0133
Echinococcus multilocularis tumor protein p63 0.0364 0.4821 0.4821
Echinococcus granulosus RUN 0.0021 0.0141 0.0141
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0504 0.0504
Plasmodium falciparum thioredoxin reductase 0.0014 0.0044 0.0107
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0195 0.0654
Brugia malayi hypothetical protein 0.0095 0.1147 0.1802
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0128 0.0197
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0044 0.003
Brugia malayi hypothetical protein 0.0021 0.0133 0.0209
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0049 0.0012
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0098 0.1187 0.1865
Brugia malayi PXA domain containing protein 0.0021 0.0133 0.0209
Brugia malayi hypothetical protein 0.0021 0.0133 0.0209
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.1235 0.1235
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0504 0.1082
Brugia malayi cell division control protein 2 homolog 0.0048 0.0504 0.0792
Trichomonas vaginalis cyclins, putative 0.008 0.0947 0.111
Schistosoma mansoni CD36-like class B scavenger receptor 0.0135 0.1694 0.1694
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Giardia lamblia Kinase, PLK 0.0103 0.1261 0.2964
Trypanosoma brucei ISWI complex protein 0.0016 0.0076 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0057 0.0632 0.2625
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.145 0.145
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0342 0.0701
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0383 0.0436
Brugia malayi Troponin I 0.0115 0.1422 0.2234
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0195 0.0755
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Echinococcus multilocularis cyclin B3 1 0.0033 0.0308 0.0308
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0395 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0047 0.049 0.077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.145 0.1712
Schistosoma mansoni lozenge 0.006 0.0668 0.0668
Loa Loa (eye worm) hypothetical protein 0.0135 0.1694 0.2662
Trichomonas vaginalis cyclin A, putative 0.008 0.0947 0.111
Schistosoma mansoni pyruvate kinase 0.0036 0.0342 0.0342
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.022 0.0346
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.003 0.0264 0.0415
Mycobacterium ulcerans hypothetical protein 0.0018 0.0094 0.0129
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0049 0.0036
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.1953 0.4494
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0383 0.0436
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0195 0.0356
Brugia malayi Troponin T 0.0068 0.0783 0.123
Echinococcus multilocularis bloom syndrome protein 0.007 0.081 0.081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0876 0.1025
Brugia malayi hypothetical protein 0.0068 0.0783 0.123
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0469 0.0539
Trypanosoma cruzi ISWI complex protein 0.0016 0.0076 0.0076
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0189 0.2426 0.3812
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.022 0.0415
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0094 0.0116
Loa Loa (eye worm) hypothetical protein 0.0051 0.0547 0.086
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Schistosoma mansoni caspase-7 (C14 family) 0.0057 0.0632 0.0632
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.1182 0.1391
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.028 0.028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0383 0.0436
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Schistosoma mansoni hypothetical protein 0.0016 0.0076 0.0076
Brugia malayi glutaminase DH11.1 0.0295 0.3872 0.6082
Loa Loa (eye worm) hypothetical protein 0.0135 0.1694 0.2662
Schistosoma mansoni tyrosinase precursor 0.0089 0.1064 0.1064
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0042 0.0418 0.1709
Loa Loa (eye worm) troponin T 0.0068 0.0783 0.123
Plasmodium falciparum phosphoglycerate kinase 0.0184 0.2354 1
Brugia malayi glutathione reductase 0.0041 0.0408 0.064
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0044 0.0044
Brugia malayi Inositol-1 0.004 0.0395 0.062
Onchocerca volvulus 0.008 0.0947 0.1488
Loa Loa (eye worm) hypothetical protein 0.0096 0.1157 0.1818
Loa Loa (eye worm) runx1 0.006 0.0668 0.105
Trypanosoma brucei phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.145 0.3673
Trypanosoma brucei metacaspase 0.0057 0.0632 0.1384
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1261 0.1981
Schistosoma mansoni hypothetical protein 0.0022 0.0155 0.0155
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0752 0.0752
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.014 0.014
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0044 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Giardia lamblia DNA damage repair protein 0.0018 0.0094 0.012
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0504 0.1082
Echinococcus multilocularis caspase 2 0.0057 0.0632 0.0632
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0342 0.0778
Leishmania major mitochondrial DNA polymerase beta 0.0326 0.4293 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0729 0.0729
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1261 0.2864
Loa Loa (eye worm) glutathione reductase 0.0041 0.0408 0.064
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0499 0.1071
Brugia malayi CHD4 protein 0.0014 0.0047 0.0074
Brugia malayi Death domain containing protein 0.0014 0.0041 0.0064
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0098 0.1187 0.1187
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0752 0.3063
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0342 0.0537
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0195 0.0755
Brugia malayi jmjC domain containing protein 0.0027 0.022 0.0346
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0632 0.0632
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0102 0.0102
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.014 0.0226
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0103 0.036
Plasmodium falciparum pyruvate kinase 0.0036 0.0342 0.1383
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0283 0.1131
Loa Loa (eye worm) hypothetical protein 0.0053 0.0579 0.0909
Schistosoma mansoni hypothetical protein 0.0066 0.0751 0.0751
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0326 0.4293 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0822 0.0822
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0504 0.0504
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0133 0.0133
Echinococcus granulosus flap endonuclease 1 0.0028 0.0234 0.0234
Echinococcus granulosus lysine specific demethylase 5A 0.0104 0.1263 0.1263
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1261 0.2864
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0042 0.0418 0.0418
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0102 0.0102
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0395 0.1517
Loa Loa (eye worm) RecQ helicase 0.007 0.081 0.1272
Echinococcus granulosus cyclins 0.0033 0.0308 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0426 0.0487
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0094 0.0319
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0504 0.0792
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1261 0.1261
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0383 0.0436
Schistosoma mansoni DNA helicase recq5 0.0042 0.0418 0.0418
Schistosoma mansoni alpha-glucosidase 0.0151 0.1914 0.1914
Trypanosoma brucei protein kinase, putative 0.0056 0.0619 0.1353
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0128 0.0204
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0098 0.1187 0.2691
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0504 0.058
Schistosoma mansoni cd36 antigen 0.0051 0.0547 0.0547
Loa Loa (eye worm) hypothetical protein 0.0046 0.0479 0.0752
Schistosoma mansoni protein phosphatase 2C 0.0027 0.022 0.022
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0158 0.0158
Onchocerca volvulus 0.0055 0.0596 0.0936
Echinococcus multilocularis CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Loa Loa (eye worm) troponin 0.0068 0.0783 0.123
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1261 0.1486
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0195 0.0395
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0041 0.0041
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.014 0.0519
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0128 0.0363
Echinococcus granulosus dna polymerase kappa 0.0086 0.1023 0.1023
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0049 0.0036
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0089 0.1064 0.1671
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Schistosoma mansoni DNA helicase recq1 0.0042 0.0418 0.0418
Schistosoma mansoni kinase 0.0053 0.0578 0.0578
Trichomonas vaginalis cyclin D, putative 0.0033 0.0308 0.0346
Schistosoma mansoni z-protein (S1r protein) 0.003 0.0264 0.0264
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0094 0.0116
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.022 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.022 0.0862
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0448 0.0448
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Trypanosoma brucei unspecified product 0.0079 0.0926 0.2075
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0128 0.0204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0504 0.0792
Schistosoma mansoni hypothetical protein 0.0012 0.0019 0.0019
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0619 0.1353
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0476 0.1016
Loa Loa (eye worm) tyrosinase 1 0.0089 0.1064 0.1671
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0342 0.0386
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.1064 0.1671
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0133 0.0133
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0049 0.0012
Leishmania major hypothetical protein, conserved 0.0027 0.022 0.0415
Brugia malayi Muscleblind-like protein 0.0161 0.2048 0.3218
Echinococcus multilocularis muscleblind protein 1 0.0161 0.2048 0.2048
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0632 0.2625
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0557 0.0557
Loa Loa (eye worm) hypothetical protein 0.0057 0.0632 0.0993
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0553 0.0553
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0133 0.0209
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0019 0.0019
Trypanosoma brucei Metacaspase-4 0.0057 0.0632 0.1384
Giardia lamblia G2/mitotic-specific cyclin B 0.008 0.0947 0.2199
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.016 0.2027 0.3185
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0103 0.1262 0.5272
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0019 0.0000000011294
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0395 0.0916
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0019 0.0019
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0307 0.0307
Echinococcus granulosus cyclin B 0.008 0.0947 0.0947
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.145 0.145
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Onchocerca volvulus Cell death protein 3 homolog 0.0057 0.0632 0.0993
Loa Loa (eye worm) hypothetical protein 0.0036 0.0342 0.0537
Echinococcus multilocularis pyruvate kinase 0.0018 0.0103 0.0103
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0055 0.0596 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Loa Loa (eye worm) troponin I 0.0115 0.1422 0.2234
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0487 0.1041
Toxoplasma gondii thioredoxin reductase 0.0041 0.0408 0.1664
Loa Loa (eye worm) hypothetical protein 0.0079 0.0928 0.1457
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0161 0.2048 0.3218
Schistosoma mansoni jun-related protein 0.0066 0.0751 0.0751
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1261 0.1261
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1261 0.1981
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0476 0.1016
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0415 0.0415
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0128 0.0197
Echinococcus multilocularis pyruvate kinase 0.0028 0.0239 0.0239
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0395 0.0825
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0111 0.0175
Entamoeba histolytica phosphoglycerate kinase, putative 0.0184 0.2354 0.2794
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0653
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0415 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Echinococcus multilocularis CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0395 0.0449
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0729 0.1612
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0619 0.0718
Brugia malayi PHD-finger family protein 0.0027 0.0218 0.0342
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0474 0.0474
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.1607 0.2525
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0128 0.0197
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0383 0.0436
Echinococcus multilocularis caspase 0.0136 0.1702 0.1702
Brugia malayi Protein kinase domain containing protein 0.0016 0.0066 0.0103
Leishmania major phosphoglycerate kinase C, glycosomal 0.0184 0.2354 0.5437
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0413 0.0413
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Loa Loa (eye worm) hypothetical protein 0.003 0.0264 0.0415
Brugia malayi Flap endonuclease-1 0.0028 0.0234 0.0368
Schistosoma mansoni netrin receptor unc5 0.0014 0.0041 0.0041
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0044 0.0044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0383 0.0436
Giardia lamblia Phosphoglycerate kinase 0.0184 0.2354 0.5627
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.028 0.028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Loa Loa (eye worm) hypothetical protein 0.0372 0.4925 0.7738
Plasmodium falciparum fructose-bisphosphate aldolase 0.0098 0.1187 0.5003
Brugia malayi Cyclin, N-terminal domain containing protein 0.0033 0.0308 0.0484
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0195 0.0755
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0426 0.0487
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0128 0.0201
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0133 0.0133
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0752 0.1849
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0078
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0166 0.2121 0.2121
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0383 0.0436
Brugia malayi 6-phosphofructokinase 0.0117 0.145 0.2278
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0067
Echinococcus granulosus Chromobox protein 3 0.0012 0.0019 0.0019
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0057 0.0632 0.0993
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0553 0.0553
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0469 0.0539
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0195 0.2506 0.3937
Plasmodium vivax SET domain protein, putative 0.0033 0.0307 0.1231
Schistosoma mansoni blooms syndrome DNA helicase 0.0049 0.0521 0.0521
Brugia malayi Doublecortin family protein 0.0021 0.0141 0.0222
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0479 0.0753
Leishmania major phosphoglycerate kinase B, cytosolic 0.0184 0.2354 0.5437
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0876 0.1025
Brugia malayi CD36 family protein 0.0135 0.1694 0.2662
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0029 0.0249 0.0249
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0752 0.1849
Leishmania major trypanothione reductase 0.0041 0.0408 0.0856
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0383 0.0602
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.065 0.065
Brugia malayi hypothetical protein 0.0478 0.6365 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0094 0.0116
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0041 0.0064
Brugia malayi PHD-finger family protein 0.0031 0.028 0.044
Loa Loa (eye worm) hypothetical protein 0.0478 0.6365 1
Onchocerca volvulus 0.0051 0.0553 0.0869
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0383 0.0436
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0141 0.0524
Giardia lamblia DINP protein human, muc B family 0.0064 0.0729 0.1668
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0619 0.0718
Echinococcus multilocularis cyclin B 0.008 0.0947 0.0947
Echinococcus granulosus chromobox protein 1 0.0075 0.0876 0.0876
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0504 0.1082
Plasmodium vivax glutathione reductase, putative 0.0041 0.0408 0.1664
Schistosoma mansoni phosphoglycerate kinase 0.0184 0.2354 0.2354
Onchocerca volvulus 0.0089 0.1064 0.1671
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0141 0.0524
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0326 0.4293 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.1953 0.4494
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0184 0.2354 0.5437
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0141 0.0141
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0418 0.1709
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.022 0.0346
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0049 0.0036
Schistosoma mansoni peptidylglycine monooxygenase 0.0372 0.4925 0.4925
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0019 0.003
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0133 0.0209
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0557 0.0557
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0729 0.0729
Brugia malayi Glycosyl hydrolases family 31 protein 0.0176 0.2247 0.3531
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0395 0.0449
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0141 0.0141
Trypanosoma brucei phosphoglycerate kinase 0.0067 0.077 0.1709
Giardia lamblia Sgs1 DNA helicase, putative 0.0042 0.0418 0.0911
Echinococcus granulosus dual specificity 0.0098 0.1182 0.1182
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0342 0.0701
Schistosoma mansoni regulator of G protein signaling 0.003 0.0264 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0504 0.0504
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0283 0.1035
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0752 0.1666
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0158 0.0248
Onchocerca volvulus 0.0071 0.0823 0.1293
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.028 0.028
Echinococcus granulosus jun protein 0.0081 0.0958 0.0958
Brugia malayi Phosphoglycerate kinase 0.0184 0.2354 0.3699
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0258 0.0286
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0049 0.0078
Trypanosoma brucei phosphoglycerate kinase 0.0184 0.2354 0.5437
Brugia malayi 6-phosphofructokinase 0.0117 0.145 0.2278
Leishmania major DNA damage repair protein, putative 0.0018 0.0094 0.0116
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.022 0.022
Schistosoma mansoni troponin I 0.0115 0.1422 0.1422
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0055 0.0596 0.0596
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Echinococcus granulosus cyclin B3 1 0.0033 0.0308 0.0308
Mycobacterium tuberculosis Conserved hypothetical protein 0.0172 0.2191 0.9293
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.145 0.145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Echinococcus multilocularis troponin i 0.0115 0.1422 0.1422
Echinococcus multilocularis lysosomal alpha glucosidase 0.0176 0.2247 0.2247
Trichomonas vaginalis set domain proteins, putative 0.0257 0.3351 0.3987
Schistosoma mansoni pyruvate kinase 0.0036 0.0342 0.0342
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0049 0.0078
Echinococcus granulosus CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.008 0.0947 0.2125
Mycobacterium ulcerans DNA polymerase IV 0.0086 0.1023 0.2557
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0176 0.2247 0.3531
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0019 0.0000000011294
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0372 0.4925 0.4925
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0264 0.0264
Chlamydia trachomatis pyruvate kinase 0.0036 0.0342 0.1289
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0504 0.0504
Brugia malayi Protein cec-1. 0.0012 0.0019 0.003
Trypanosoma brucei mitotic cyclin 6 0.008 0.0947 0.2125
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0136 0.1702 0.1702
Echinococcus multilocularis pyruvate kinase 0.0036 0.0342 0.0342
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0383 0.0602
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0021 0.014 0.022
Brugia malayi chromobox protein homolog 3 0.0042 0.0426 0.0669
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0098 0.1187 0.1187
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0102 0.0102
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0158 0.0248
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.145 0.2278
Brugia malayi mbt repeat family protein 0.0051 0.0553 0.0869
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.1263 0.1985
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0128 0.0201
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0086 0.1023 0.1201
Onchocerca volvulus 0.0023 0.0163 0.0256
Echinococcus granulosus cyclins 0.0033 0.0308 0.0308
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0184 0.2354 1
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0098 0.1187 0.2691
Entamoeba histolytica cyclin, putative 0.0033 0.0308 0.0346
Loa Loa (eye worm) hypothetical protein 0.0096 0.1157 0.1818
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0184 0.2354 0.2794
Plasmodium falciparum glutathione reductase 0.0014 0.0044 0.0107
Loa Loa (eye worm) glutaminase 0.0295 0.3872 0.6082
Echinococcus granulosus caspase 0.0136 0.1702 0.1702
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0183 0.0183
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0876 0.1376
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0195 0.0356
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0098 0.1187 0.1865
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.022 0.0862
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0133 0.0133
Trichomonas vaginalis cyclin B, putative 0.008 0.0947 0.111
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0135 0.1694 0.2662
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0098 0.1182 0.2678
Loa Loa (eye worm) glutaminase 2 0.0295 0.3872 0.6082
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Mycobacterium tuberculosis Probable oxidoreductase 0.0103 0.1262 0.5272
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0133 0.0133
Schistosoma mansoni troponin I 0.0115 0.1422 0.1422
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0184 0.2354 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0418 0.1709
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0141 0.0141
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0372 0.4925 0.4925
Brugia malayi jmjC domain containing protein 0.0027 0.022 0.0346
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0158 0.0158
Echinococcus multilocularis dna polymerase eta 0.0085 0.1006 0.1006
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.1182 0.1182
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0019 0.0019
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0094 0.0319
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0209
Plasmodium vivax protein kinase Crk2 0.0048 0.0504 0.2076
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0632 0.0733
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0128 0.013
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0136 0.1702 0.1702
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0476 0.1016
Echinococcus multilocularis chromobox protein 1 0.0075 0.0876 0.0876
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0057 0.0632 0.0632
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0019 0.003
Echinococcus granulosus cyclins 0.0033 0.0308 0.0308
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0752 0.1181
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0042 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.0068 0.0783 0.123
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0342 0.0537
Schistosoma mansoni dopamine-beta-monooxygenase 0.0704 0.9458 0.9458
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0128 0.013
Echinococcus multilocularis Ankyrin 0.0014 0.0042 0.0042
Echinococcus granulosus pyruvate kinase 0.0018 0.0103 0.0103
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0619 0.1353
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0469 0.0737
Giardia lamblia Fructose-bisphosphate aldolase 0.0315 0.415 1
Echinococcus multilocularis cyclins 0.0033 0.0308 0.0308
Onchocerca volvulus 0.009 0.1074 0.1687
Onchocerca volvulus 0.0053 0.0579 0.0909
Echinococcus granulosus cyclin b3 0.0033 0.0308 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0019 0.003
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0044 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Schistosoma mansoni tyrosinase precursor 0.0089 0.1064 0.1064
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0098 0.1182 0.1857
Loa Loa (eye worm) hypothetical protein 0.0051 0.0553 0.0869
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0047 0.0047
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0133 0.0133
Plasmodium falciparum metacaspase 1 0.0057 0.0632 0.2625
Echinococcus multilocularis CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0408 0.064
Plasmodium falciparum glutathione reductase 0.0041 0.0408 0.1664
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0342 0.0537
Schistosoma mansoni zinc finger protein 0.0016 0.0076 0.0076
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.1064 0.1671
Onchocerca volvulus 0.0071 0.0823 0.1293
Trichomonas vaginalis DNA helicase recq1, putative 0.007 0.081 0.0946
Echinococcus multilocularis Chromo domain 0.0012 0.0019 0.0019
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0234 0.0463
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0619 0.0619
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0055 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0209
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0234 0.0448
Trypanosoma brucei DNA polymerase IV, putative 0.0086 0.1023 0.2304
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0342 0.0701
Leishmania major pyruvate kinase 0.0036 0.0342 0.0701
Toxoplasma gondii exonuclease III APE 0.002 0.0128 0.0466
Brugia malayi hypothetical protein 0.0051 0.0547 0.086
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0183 0.0183
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0619 0.0619
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0557 0.0557
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0504 0.058
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0183 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0504 0.058
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0184 0.2354 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0024 0.0024
Brugia malayi Troponin T 0.0068 0.0783 0.123
Brugia malayi Uncoordinated protein 44 0.0014 0.0041 0.0064
Onchocerca volvulus 0.0046 0.0474 0.0745
Loa Loa (eye worm) helicase 0.0012 0.0019 0.003
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.022 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0485 0.1037
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0744 0.1648
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0553 0.0553
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0195 0.0654
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0166 0.2121 0.2121
Echinococcus granulosus muscleblind protein 0.0161 0.2048 0.2048
Schistosoma mansoni chromobox protein 0.0012 0.0019 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.022 0.0346
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0619 0.0972
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0098 0.1187 0.1187
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0372 0.4925 0.4925
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0094 0.0116
Echinococcus granulosus cyclins 0.0033 0.0308 0.0308
Echinococcus multilocularis zinc finger protein 0.0021 0.0139 0.0139
Treponema pallidum ATP-dependent DNA helicase 0.0021 0.014 0.0234
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0752 0.0752
Entamoeba histolytica hypothetical protein 0.0021 0.0133 0.0137
Brugia malayi polk-prov protein 0.0046 0.0485 0.0761
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0632 0.0632
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0418 0.0657
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0625 0.8377 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0093 0.112 0.4659
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0044 0.0107
Entamoeba histolytica hypothetical protein 0.0025 0.0195 0.0211
Entamoeba histolytica recQ family helicase, putative 0.0047 0.0499 0.0574
Trypanosoma cruzi cyclin, putative 0.008 0.0947 0.2125
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.038 0.038
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0133 0.0133
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.022 0.022
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0133 0.0133
Echinococcus granulosus CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0049 0.0036
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0133 0.0133
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0041 0.0064
Onchocerca volvulus Alhambra homolog 0.0031 0.028 0.044
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0342 0.0537
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.065 0.065
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0619 0.1353
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0093 0.112 0.4659
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0283 0.1131
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0158 0.0248
Echinococcus granulosus caspase 8 0.0057 0.0632 0.0632
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0094 0.0094
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.145 0.6085
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0553 0.0869
Echinococcus multilocularis Protein lozenge 0.006 0.0668 0.0668
Schistosoma mansoni phosphoglycerate kinase 0.0184 0.2354 0.2354
Loa Loa (eye worm) hypothetical protein 0.0059 0.065 0.1021
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.022 0.022
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Plasmodium falciparum cyclin 0.0033 0.0308 0.1238
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0044 0.0107
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.038 0.038
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.028 0.044
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0098 0.1187 0.1187
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.145 0.1712
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0307 0.0307
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Schistosoma mansoni eyes absent homolog 0.0095 0.1147 0.1147
Entamoeba histolytica recQ family helicase, putative 0.002 0.0129 0.0132
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0383 0.1559
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0133 0.0209
Plasmodium falciparum phd finger protein, putative 0.0031 0.028 0.1118
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0663 0.0663
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.145 0.145
Onchocerca volvulus 0.0012 0.0019 0.003
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0133 0.0133
Echinococcus granulosus phosphoglycerate kinase 1 0.0184 0.2354 0.2354
Echinococcus multilocularis chromobox protein 1 0.0075 0.0876 0.0876
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0025 0.0191 0.0735
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0195 0.0654
Loa Loa (eye worm) hypothetical protein 0.0045 0.0468 0.0735
Loa Loa (eye worm) hypothetical protein 0.0042 0.0418 0.0657
Plasmodium falciparum metacaspase-like protein 0.0057 0.0632 0.2625
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0133 0.0133
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0068 0.0783 0.123
Entamoeba histolytica cyclin family protein 0.0033 0.0308 0.0346
Brugia malayi ShTK domain containing protein 0.0089 0.1064 0.1671
Trypanosoma brucei phosphoglycerate kinase 0.0184 0.2354 0.5437
Brugia malayi Bromodomain containing protein 0.0081 0.0954 0.1499
Trichomonas vaginalis cyclins, putative 0.0055 0.0601 0.0696
Brugia malayi phosphofructokinase 0.0117 0.145 0.2278
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0044 0.045 0.0708
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.145 0.1712
Brugia malayi PHD-finger family protein 0.0012 0.002 0.0031
Brugia malayi SET domain containing protein 0.0015 0.0051 0.0081
Brugia malayi hypothetical protein 0.0021 0.0141 0.0222
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0553 0.0553
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0041 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0133 0.0133
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0504 0.1082
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0133 0.0209
Loa Loa (eye worm) DOMON domain-containing protein 0.0071 0.0823 0.1293
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0098 0.1187 0.5003
Loa Loa (eye worm) hypothetical protein 0.0076 0.0891 0.14
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Echinococcus granulosus caspase 3 0.0078 0.0921 0.0921
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0504 0.058
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0372 0.4925 0.7738
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0234 0.0234
Onchocerca volvulus 0.0055 0.0596 0.0936
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0926 0.2075
Echinococcus multilocularis chromobox protein 2 0.0012 0.0019 0.0019
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.044 0.1802
Trichomonas vaginalis DNA helicase recq, putative 0.007 0.081 0.0946
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.1263 0.1263
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.145 0.1712
Giardia lamblia Pyruvate kinase 0.0036 0.0342 0.0725
Trypanosoma brucei metacaspase MCA2 0.0057 0.0632 0.1384
Brugia malayi regulator of G-protein signaling egl-10 0.003 0.0264 0.0415
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.145 0.3309
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0553 0.0869
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0619 0.2568
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0133 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0408 0.0856
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0418 0.0657
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0049 0.0036
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0504 0.2076
Trypanosoma brucei DNA polymerase eta, putative 0.0085 0.1006 0.2265
Brugia malayi Cyclin, N-terminal domain containing protein 0.008 0.0947 0.1488
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0744 0.3106
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0128 0.0363
Trypanosoma brucei RNA helicase, putative 0.0112 0.1374 0.3129
Trichomonas vaginalis cyclins, putative 0.008 0.0947 0.111
Loa Loa (eye worm) hypothetical protein 0.0051 0.0547 0.086
Echinococcus multilocularis L aminoadipate semialdehyde 0.009 0.1074 0.1074
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0383 0.0798
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0744 0.0744
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0283 0.0582
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0019 0.0000000011294
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Echinococcus granulosus Chromo domain 0.0012 0.0019 0.0019
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0141 0.0141
Schistosoma mansoni troponin I 0.0115 0.1422 0.1422
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0504 0.058
Loa Loa (eye worm) hypothetical protein 0.0052 0.0557 0.0876
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0133 0.0137
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0752 0.0752
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0283 0.1131
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0042 0.0418 0.0418
Schistosoma mansoni inositol monophosphatase 0.004 0.0395 0.0395
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0744 0.1829
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0154 0.1951 0.8255
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Schistosoma mansoni SET domain protein 0.0015 0.0052 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0019 0.00000000031556
Brugia malayi jmjC domain containing protein 0.0027 0.022 0.0346
Leishmania major DNA polymerase eta, putative 0.0045 0.0468 0.0998
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0744 0.0744
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0958 0.0958
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0342 0.0537
Echinococcus granulosus peregrin 0.0044 0.0455 0.0455
Brugia malayi Thioredoxin reductase 0.0041 0.0408 0.064
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Giardia lamblia Hypothetical protein 0.0033 0.0308 0.0643
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0044 0.0107
Leishmania major cyclin 0.008 0.0947 0.2125
Leishmania major metacaspase, putative 0.0057 0.0632 0.1384
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0098 0.1187 0.1187
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0019 0.0019
Schistosoma mansoni rab6-interacting 0.0021 0.0141 0.0141
Echinococcus multilocularis lysosomal alpha glucosidase 0.0176 0.2247 0.2247
Trypanosoma cruzi DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Brugia malayi Troponin T 0.0068 0.0783 0.123
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0154 0.1951 0.8132
Plasmodium falciparum protein kinase 5 0.0048 0.0504 0.2076
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Schistosoma mansoni CD36-like class B scavenger receptor 0.0135 0.1694 0.1694
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0098 0.1187 0.1187
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0044 0.0107
Trichomonas vaginalis cyclin D, putative 0.0033 0.0308 0.0346
Plasmodium vivax metacaspase 1, putative 0.0057 0.0632 0.2625
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0133 0.0137
Brugia malayi Bromodomain containing protein 0.0034 0.0315 0.0495
Echinococcus granulosus lysosome membrane protein 2 0.0135 0.1694 0.1694
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0044 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Echinococcus multilocularis phosphoglycerate kinase 1 0.0184 0.2354 0.2354
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0744 0.0744
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0504 0.0504
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0057 0.0632 0.2625
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0342 0.1289
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0064 0.0729 0.3039
Trypanosoma cruzi cyclin 6, putative 0.008 0.0947 0.2125
Echinococcus multilocularis dual specificity 0.0098 0.1182 0.1182
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.009 0.1074 0.1687
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0047 0.0047
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.014 0.0226
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0133 0.0209
Brugia malayi DOMON domain containing protein 0.0071 0.0823 0.1293
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0395 0.0825
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0264 0.0264
Schistosoma mansoni rab6-interacting 0.0021 0.0141 0.0141
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.028 0.1118
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0029 0.0249 0.0249
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0822 0.1831
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0057 0.0632 0.2625
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0115 0.1422 0.2234
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0283 0.0316
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.002 0.0129 0.0472
Leishmania major fructose-1,6-bisphosphate aldolase 0.0098 0.1187 0.2691
Trichomonas vaginalis cyclins, putative 0.008 0.0947 0.111
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0098 0.1187 0.1187
Entamoeba histolytica hypothetical protein 0.0098 0.1182 0.1391
Echinococcus granulosus pyruvate kinase 0.0036 0.0342 0.0342
Echinococcus multilocularis muscleblind protein 0.0161 0.2048 0.2048
Treponema pallidum phosphoglycerate kinase 0.0184 0.2354 0.5627
Brugia malayi Cell death protein 3 precursor 0.0057 0.0632 0.0993
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.145 0.3309
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0504 0.112
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0342 0.0537
Trypanosoma cruzi metacaspase 5, putative 0.0057 0.0632 0.1384
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0047 0.0047
Echinococcus granulosus phd:f box containing protein 0.0027 0.022 0.022
Entamoeba histolytica protein kinase, putative 0.0098 0.1182 0.1391
Schistosoma mansoni pyruvate kinase 0.0018 0.0103 0.0103
Onchocerca volvulus Troponin I homolog 0.0115 0.1422 0.2234
Schistosoma mansoni jumonji domain containing protein 0.0027 0.022 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0619 0.0619
Trypanosoma brucei metacaspase 5, putative 0.0057 0.0632 0.1384
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.028 0.1118
Echinococcus multilocularis caspase 8 0.0057 0.0632 0.0632
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0822 0.0961
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0133 0.0133
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0019 0.0019
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0408 0.1574
Trypanosoma cruzi CYC2-like cyclin, putative 0.008 0.0947 0.2125
Schistosoma mansoni bromodomain containing protein 0.0068 0.0782 0.0782
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0041 0.0041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0128 0.0219
Schistosoma mansoni loxhd1 0.0021 0.0141 0.0141
Trichomonas vaginalis cyclins, putative 0.0033 0.0308 0.0346
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.1953 0.4494
Schistosoma mansoni hypothetical protein 0.0112 0.1374 0.1374
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0663 0.0663
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1261 0.1486
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0579 0.0579
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0098 0.1187 0.5003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0093 0.112 0.4659
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.1607 0.2525
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0057 0.0632 0.0733
Echinococcus multilocularis CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Mycobacterium tuberculosis Probable dehydrogenase 0.0093 0.112 0.4659
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0342 0.0679
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0342 0.1383
Echinococcus granulosus Ankyrin 0.0014 0.0042 0.0042
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0067 0.077 0.1709
Onchocerca volvulus 0.0012 0.0019 0.003
Schistosoma mansoni phd/f-box containing protein 0.0027 0.022 0.022
Echinococcus granulosus CD36 class B scavenger receptor 0.0135 0.1694 0.1694
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0207 0.2672 0.2672
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0504 0.0504
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0098 0.1187 0.2691
Loa Loa (eye worm) phosphofructokinase 0.0117 0.145 0.2278
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0632 0.0993
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0209
Brugia malayi MH2 domain containing protein 0.0129 0.1607 0.2525
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0195 0.0755
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.065 0.1021
Schistosoma mansoni hypothetical protein 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0031 0.028 0.044
Trypanosoma brucei trypanothione reductase 0.0041 0.0408 0.0856
Leishmania major pyruvate kinase 0.0036 0.0342 0.0701
Mycobacterium ulcerans glutaminase 0.0295 0.3872 1
Brugia malayi jmjC domain containing protein 0.0166 0.2121 0.3331
Trichomonas vaginalis cyclin B, putative 0.008 0.0947 0.111
Schistosoma mansoni troponin t invertebrate 0.0143 0.18 0.18
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0094 0.0116
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Echinococcus multilocularis jun protein 0.0081 0.0958 0.0958
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0044 0.0451 0.1849
Echinococcus granulosus caspase 2 0.0057 0.0632 0.0632
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0625 0.8377 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0103 0.1262 0.5272
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.415 0.4942
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0184 0.2354 0.5437
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0133 0.0133
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0274 0.0274
Onchocerca volvulus 0.0089 0.1064 0.1671
Brugia malayi N-terminal motif family protein 0.0195 0.2506 0.3937
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0098 0.1187 0.1187
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0044 0.0044
Schistosoma mansoni ap endonuclease 0.002 0.0128 0.0128
Echinococcus multilocularis dna polymerase kappa 0.0086 0.1023 0.1023
Brugia malayi fructose-bisphosphate aldolase 2 0.0098 0.1187 0.1865
Brugia malayi Heterochromatin protein 1 0.0075 0.0876 0.1376
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0958 0.0958
Echinococcus granulosus cyclins 0.0033 0.0308 0.0308
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0047 0.0499 0.1071
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.077 0.1709
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0744 0.1829
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0133 0.0133
Onchocerca volvulus 0.0055 0.0596 0.0936
Trypanosoma cruzi metacaspase 5, putative 0.0057 0.0632 0.1384
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0283 0.1131
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0019 0.00000000031556
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0128 0.0466
Leishmania major hypothetical protein, conserved 0.0016 0.0076 0.0076
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0041 0.0041
Giardia lamblia Cyclin A 0.0033 0.0308 0.0643
Trypanosoma cruzi metacaspase, putative 0.0057 0.0632 0.1384
Trypanosoma cruzi metacaspase, putative 0.0057 0.0632 0.1384
Brugia malayi Phosphoglycerate kinase 0.0067 0.077 0.121
Trypanosoma cruzi metacaspase, putative 0.0057 0.0632 0.1384
Brugia malayi Bloom's syndrome protein homolog 0.007 0.081 0.1272
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0049 0.0012
Plasmodium vivax phosphoglycerate kinase, putative 0.0184 0.2354 1
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0372 0.4925 0.7738
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0737 0.1157
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0342 0.1383
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0504 0.0504
Echinococcus multilocularis RUN 0.0021 0.0141 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0487 0.1041
Trypanosoma brucei glucosidase, putative 0.0039 0.0383 0.0798
Entamoeba histolytica hypothetical protein 0.0021 0.0133 0.0137
Onchocerca volvulus 0.0478 0.6365 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0557 0.0557
Trypanosoma cruzi cyclin, putative 0.008 0.0947 0.2125
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0559 0.0646
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0098 0.1187 0.1187
Toxoplasma gondii hypothetical protein 0.0053 0.0568 0.235
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0234 0.0258
Schistosoma mansoni cyclins 0.0033 0.0308 0.0308
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0133 0.0133
Schistosoma mansoni polycystin 1-related 0.0021 0.0141 0.0141
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0044 0.0107
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.003
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0283 0.0316
Loa Loa (eye worm) hypothetical protein 0.0057 0.0632 0.0993
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.1023 0.2304
Schistosoma mansoni alpha glucosidase 0.0039 0.0383 0.0383
Brugia malayi Troponin family protein 0.0115 0.1422 0.2234
Plasmodium vivax hypothetical protein, conserved 0.0031 0.028 0.1118
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0184 0.2354 1
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0504 0.1082
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0141 0.0222
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0052 0.0082
Schistosoma mansoni DNA polymerase eta 0.0085 0.1006 0.1006
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0283 0.1131
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0632 0.0733
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0154 0.1951 0.4982
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0383 0.0798
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0487 0.1041
Schistosoma mansoni flap endonuclease-1 0.0025 0.0198 0.0198
Brugia malayi Pre-SET motif family protein 0.0033 0.0307 0.0482
Brugia malayi DOMON domain containing protein 0.0071 0.0823 0.1293
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0049 0.0036
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0184 0.2354 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1261 0.1261

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 50 nM Inhibition of human SRB1-mediated Hepatitis C virus genotype 2a entry into human HuH7.5 cells by luciferase reporter gene assay ChEMBL. 22784640

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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