Detailed information for compound 172672

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 411.277 | Formula: C18H22INO2
  • H donors: 0 H acceptors: 1 LogP: 3.78 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: I/C=C\COC(=O)C1C2CCC(N2C)CC1c1ccccc1
  • InChi: 1S/C18H22INO2/c1-20-14-8-9-16(20)17(18(21)22-11-5-10-19)15(12-14)13-6-3-2-4-7-13/h2-7,10,14-17H,8-9,11-12H2,1H3/b10-5-
  • InChiKey: PTARSFHGDDMYOJ-YHYXMXQVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Dopamine transporter   619 aa 509 aa 40.1 %
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Dopamine transporter   619 aa 604 aa 37.9 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Dopamine transporter   619 aa 599 aa 44.2 %
Plasmodium vivax hypothetical protein, conserved Dopamine transporter   619 aa 657 aa 20.1 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Dopamine transporter   619 aa 522 aa 36.0 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Dopamine transporter   619 aa 557 aa 23.9 %
Echinococcus multilocularis sodium and chloride dependent glycine Dopamine transporter   619 aa 599 aa 41.9 %
Neospora caninum sodium-dependent transporter, putative Dopamine transporter   619 aa 498 aa 32.3 %
Schistosoma mansoni sodium/chloride dependent transporter Dopamine transporter   619 aa 588 aa 40.3 %
Brugia malayi Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 578 aa 33.4 %
Onchocerca volvulus Transmembrane protein 120 homolog Dopamine transporter   619 aa 578 aa 32.9 %
Schistosoma mansoni sodium/chloride dependent transporter Dopamine transporter   619 aa 558 aa 41.8 %
Onchocerca volvulus Dopamine transporter   619 aa 612 aa 23.5 %
Echinococcus granulosus sodium and chloride dependent glycine Dopamine transporter   619 aa 594 aa 41.4 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 578 aa 32.9 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 636 aa 31.8 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Dopamine transporter   619 aa 551 aa 39.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi hypothetical protein 0.0198 0.1072 0.2095
Echinococcus multilocularis N chimaerin 0.0528 0.2979 0.2979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Leishmania major protein kinase, putative 0.0016 0.0024 0.0082
Echinococcus multilocularis tensin 0.0528 0.2979 0.2979
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis nuclear factor of activated T cells 5 0.004 0.0165 0.0165
Loa Loa (eye worm) phosphofructokinase 0.0055 0.0248 0.0475
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0371 0.2071 0.2071
Mycobacterium ulcerans 6-phosphofructokinase 0.0055 0.0248 0.3312
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0227 0.0444
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Schistosoma mansoni tensin-related 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi cytochrome P450 0.0013 0.0007 0.0013
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0249 0.1175
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi ecdysteroid receptor 0.0041 0.017 0.0332
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0019 0.017
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0204 0.0953
Brugia malayi nuclear hormone receptor 0.0019 0.0044 0.0087
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis kinase suppressor of Ras 1 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0899 0.5117 1
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.017 0.0323
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable reductase 0.0054 0.0245 0.3278
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi protein kinase, putative 0.0371 0.2071 0.9986
Leishmania major cysteine peptidase A (CPA) 0.0019 0.004 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.017 0.0323
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus tyrosine kinase 0.0899 0.5117 0.5117
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.004 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Echinococcus granulosus expressed conserved protein 0.0528 0.2979 0.2979
Leishmania major protein kinase, putative 0.0016 0.0024 0.0082
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0044 0.0044
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0371 0.2071 0.2071
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0183 0.0183
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis rotamase, putative 0.0036 0.0138 0.0647
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Schistosoma mansoni cytochrome P450 0.0013 0.0007 0.0007
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0019 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Echinococcus multilocularis RUN 0.0013 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0058 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus serotonin transporter 0.0109 0.0564 0.0564
Brugia malayi conserved hypotetical protein 0.0019 0.0044 0.0087
Echinococcus multilocularis 0.0013 0.0007 0.0007
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.015 0.015
Entamoeba histolytica ankyrin repeat protein 0.0371 0.2071 0.4047
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0899 0.5117 0.5117
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.0564 0.1094
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Onchocerca volvulus Cathepsin L homolog 0.0019 0.004 0.007
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0528 0.2979 0.5818
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Brugia malayi ephrin receptor 1 precursor 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0054 0.0245 0.3278
Brugia malayi nuclear receptor RXR 0.0019 0.0044 0.0087
Echinococcus granulosus receptor type guanylyl cyclase 0.0371 0.2071 0.2071
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0899 0.5117 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0019 0.017
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.017 0.017
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0047 0.0193
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0019 0.0012
Schistosoma mansoni nuclear receptor 0.0019 0.0044 0.0044
Schistosoma mansoni SH2A 0.0528 0.2979 0.2979
Schistosoma mansoni flap endonuclease-1 0.0012 0.0001 0.0001
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0044 0.0044
Trichomonas vaginalis protein tyrosine kinase, putative 0.0371 0.2071 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0019 0.017
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis growth factor receptor bound protein 2 0.0528 0.2979 0.2979
Leishmania major ATP-dependent phosphofructokinase 0.0055 0.0248 0.1166
Echinococcus granulosus inositol monophosphatase 1 0.0018 0.0036 0.0036
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0528 0.2979 0.2979
Echinococcus multilocularis insulin receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Schistosoma mansoni tyrosine protein kinase 0.0371 0.2071 0.2071
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0019 0.004 0.0079
Toxoplasma gondii hypothetical protein 0.0019 0.004 0.0033
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Echinococcus granulosus Polycystic kidney disease protein 0.0013 0.0006 0.0006
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0044 0.0044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0036 0.0154
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Entamoeba histolytica receptor protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni adapter molecule crk 0.0528 0.2979 0.2979
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.004 0.004
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.1746 1 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0899 0.5117 0.5117
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0249 0.1175
Onchocerca volvulus Tyrosine kinase homolog 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Echinococcus granulosus flap endonuclease 1 0.0013 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Schistosoma mansoni ephrin receptor 0.0371 0.2071 0.2071
Trypanosoma brucei trypanothione reductase 0.0024 0.0069 0.0304
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0539 0.732
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0068
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0133 0.0614
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Echinococcus granulosus tyrosine protein kinase Blk 0.0899 0.5117 0.5117
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0015 0.0018 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.006 0.028 0.3758
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Brugia malayi SH2 domain containing protein 0.0899 0.5117 1
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0139 0.0734 0.0734
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0112 0.0112
Brugia malayi Cytochrome P450 family protein 0.0013 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.007
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0019 0.0453
Echinococcus granulosus c src tyrosine kinase 0.0899 0.5117 0.5117
Loa Loa (eye worm) protein kinase domain-containing protein 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0019 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.006 0.028 1
Schistosoma mansoni GTPase activating protein 0.0528 0.2979 0.2979
Schistosoma mansoni DNA polymerase eta 0.0091 0.0457 0.0457
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0371 0.2071 0.4047
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Plasmodium falciparum protein kinase, putative 0.0371 0.2071 0.9986
Schistosoma mansoni growth factor receptor-bound protein 0.0528 0.2979 0.2979
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0371 0.2071 0.2071
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0019 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Toxoplasma gondii thioredoxin reductase 0.0024 0.0069 0.0063
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0139 0.0734 0.352
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0899 0.5118 0.5118
Echinococcus granulosus insulin receptor 0.0371 0.2071 0.2071
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0013 0.0008 0.0001
Schistosoma mansoni glutaminase 0.0133 0.0702 0.0702
Onchocerca volvulus 0.0019 0.004 0.0068
Echinococcus multilocularis protein kinase 0.0371 0.2071 0.2071
Trypanosoma brucei Flagellum attachment zone protein 20 0.0371 0.2071 0.9986
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0539 0.732
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0024 0.0069 0.0864
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.036 0.1708
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0371 0.2071 0.2071
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0249 0.0249
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0044 0.0044
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0018 0.0053
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.017 0.0332
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0371 0.2071 0.2071
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0138 0.027
Echinococcus granulosus SH2 domain containing adapter protein F 0.0528 0.2979 0.2979
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Onchocerca volvulus Alhambra homolog 0.0031 0.0112 0.021
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0019 0.004 0.016
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.017 0.017
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0153 0.0709
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.03 0.0587
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Echinococcus multilocularis dna polymerase eta 0.0091 0.0457 0.0457
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0031 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.017 0.0323
Toxoplasma gondii cathepsin CPL 0.0019 0.004 0.0034
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/EPH protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica Flap nuclease, putative 0.0013 0.0008 0.0015
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.002 0.0038
Echinococcus granulosus activated cdc42 kinase 1 0.0371 0.2071 0.2071
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0371 0.2071 0.4047
Brugia malayi Pre-SET motif family protein 0.0102 0.052 0.1016
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0371 0.2071 0.2071
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0139 0.0734 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0227 0.3034
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0272 0.0272
Loa Loa (eye worm) DR-78 0.0019 0.0044 0.0078
Loa Loa (eye worm) TK/Met protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Brugia malayi jmjC domain containing protein 0.0039 0.0155 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Giardia lamblia Kinase, NEK 0.0371 0.2071 1
Brugia malayi Bromodomain containing protein 0.0031 0.0112 0.0219
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0899 0.5117 0.5117
Schistosoma mansoni signal transduction protein lnk-related 0.0528 0.2979 0.2979
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0021 0.0078
Onchocerca volvulus 0.0024 0.0072 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.004 0.004
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0019 0.017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Trichomonas vaginalis rotamase, putative 0.0035 0.0133 0.0624
Schistosoma mansoni ephrin receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0018 0.0053
Echinococcus granulosus fibroblast growth factor receptor 4 0.0371 0.2071 0.2071
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0371 0.2074 0.2074
Schistosoma mansoni 6-phosphofructokinase 0.0055 0.0248 0.0248
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0371 0.2071 0.2071
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0068
Leishmania major cytochrome p450-like protein 0.0017 0.0031 0.0119
Brugia malayi hypothetical protein 0.0013 0.0006 0.0013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0087 0.0436 0.0844
Loa Loa (eye worm) hypothetical protein 0.0198 0.1072 0.2088
Echinococcus multilocularis tyrosine protein kinase Blk 0.0899 0.5117 0.5117
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0371 0.2071 1
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0371 0.2071 0.2071
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0044 0.0078
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus epidermal growth factor receptor 0.0371 0.2071 0.2071
Echinococcus granulosus suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0227 0.8074
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0371 0.2071 0.4047
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0031 0.0119
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Giardia lamblia Kinase, NEK 0.0371 0.2071 0.9998
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.004 0.004
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0019 0.0028
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.0021 0.0232
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.017 0.017
Onchocerca volvulus 0.0371 0.2071 0.4041
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0371 0.2071 0.4047
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0047 0.0193
Loa Loa (eye worm) flap endonuclease-1 0.0013 0.0008 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus single minded 2 0.0044 0.0184 0.0184
Schistosoma mansoni single-minded 0.0059 0.0272 0.0272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0044 0.0087
Brugia malayi Guanylyl cyclase protein 23 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0019 0.004 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni loxhd1 0.0013 0.0006 0.0006
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.03 0.4038
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0005 0.0009
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0183 0.0183
Echinococcus multilocularis tumor protein p63 0.0165 0.0884 0.0884
Giardia lamblia DINP protein human, muc B family 0.0074 0.036 0.1705
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0044 0.0087
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0371 0.2071 0.2071
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Echinococcus granulosus cpg binding protein 0.0015 0.002 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus tyrosine kinase 0.0899 0.5117 0.5117
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus dna polymerase eta 0.0091 0.0457 0.0457
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Plasmodium falciparum DNA repair protein REV1, putative 0.002 0.0047 0.0194
Echinococcus granulosus tyrosine protein kinase Src42A 0.0899 0.5117 0.5117
Brugia malayi hypothetical protein 0.0528 0.2979 0.5821
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0133 0.0614
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus multilocularis transfer RNA-Lys 0.0044 0.0184 0.0184
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0155 0.0155
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.03 0.0587
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Schistosoma mansoni protein tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi RhoGAP domain containing protein 0.0528 0.2979 0.5821
Onchocerca volvulus 0.0015 0.0021 0.0031
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0371 0.2074 0.2068
Echinococcus multilocularis tensin 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0528 0.2979 0.2979
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.03 0.03
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.017 0.017
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis epidermal growth factor receptor 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0528 0.2979 0.5818
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0227 0.0444
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0371 0.2071 1
Schistosoma mansoni nuclear receptor 0.0019 0.0044 0.0044
Brugia malayi glutaminase DH11.1 0.0133 0.0702 0.1372
Brugia malayi protein-tyrosine kinase 0.0899 0.5117 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0015 0.0018 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0018 0.0053
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114
Echinococcus granulosus integrin linked protein kinase 0.0371 0.2071 0.2071
Trypanosoma brucei unspecified product 0.0044 0.0186 0.0869
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni coup transcription factor 0.0041 0.017 0.017
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0044 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.004 0.0079
Echinococcus granulosus cathepsin l1 0.0019 0.004 0.004
Echinococcus multilocularis epidermal growth factor receptor 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis FL cytokine receptor 0.0371 0.2071 0.2071
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0528 0.2979 0.5818
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0528 0.2979 0.5818
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.004 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.017 0.0332
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.017 0.017
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0133 0.0261
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0014 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Onchocerca volvulus 0.0528 0.2979 0.5818
Plasmodium falciparum flap endonuclease 1 0.0013 0.0008 0.0007
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0144 0.0764 0.1486
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Onchocerca volvulus 0.0528 0.2979 0.5818
Echinococcus multilocularis NCK adaptor protein 0.0528 0.2979 0.2979
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0004
Schistosoma mansoni hypothetical protein 0.0206 0.1118 0.1118
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0042 0.0042
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0528 0.2979 0.5818
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0031 0.0052
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0539 0.2577
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.03 0.0579
Echinococcus granulosus peregrin 0.0031 0.0112 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0047 0.0193
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0013 0.0006 0.0004
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0528 0.2979 0.2979
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0018 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.017 0.0332
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0112 0.0106
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Schistosoma mansoni zinc finger protein 0.0019 0.0044 0.0044
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis cysteine protease 0.0019 0.004 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Brugia malayi hypothetical protein 0.0193 0.1043 0.2037
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0044 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0371 0.2071 0.4041
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0058 0.0058
Entamoeba histolytica receptor protein kinase, putative 0.0371 0.2071 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Plasmodium vivax DNA repair protein REV1, putative 0.002 0.0047 0.0194
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Doublecortin family protein 0.0013 0.0006 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.03 0.03
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) TK/EGFR protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.017 0.017
Onchocerca volvulus 0.0019 0.004 0.007
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0019 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Plasmodium vivax tyrosine kinase-like protein, putative 0.0371 0.2071 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0031 0.0052
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0112 0.0112
Brugia malayi bHLH-PAS transcription factor 0.0044 0.0184 0.0359
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0102 0.052 0.1008
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0044 0.0078
Schistosoma mansoni 6-phosphofructokinase 0.0055 0.0248 0.0248
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.004 0.007
Leishmania major protein kinase, putative 0.0371 0.2071 0.9986
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.017 0.0323
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0051 0.0227 0.0436
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.004 0.0163
Plasmodium vivax thioredoxin reductase, putative 0.0024 0.0069 0.0305
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Echinococcus granulosus tyrosine protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus tyrosine protein kinase shark 0.0899 0.5118 0.5118
Echinococcus multilocularis survival motor neuron protein 1 0.0193 0.1043 0.1043
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Giardia lamblia Protein 21.1 0.0371 0.2071 0.9998
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0153 0.2009
Echinococcus multilocularis tyrosine kinase 0.0899 0.5117 0.5117
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0019 0.017
Brugia malayi polk-prov protein 0.0061 0.0285 0.0558
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0371 0.2074 0.2074
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0371 0.2071 0.4041
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0249 0.1175
Onchocerca volvulus 0.0371 0.2071 0.4041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.017 0.0323
Echinococcus multilocularis transfer RNA-Thr 0.0371 0.2071 0.2071
Schistosoma mansoni thyroid hormone receptor 0.0041 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis protein kinase atn1, putative 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi tRNA modification GTPase TrmE family protein 0.0528 0.2979 0.5821
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni hypothetical protein 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/DDR protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.017 0.0332
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2074 0.4052
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0155 0.0155
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Plasmodium falciparum thioredoxin reductase 0.0024 0.0069 0.0305
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0054 0.0245 0.8724
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0112 0.0112
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0021 0.0078
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Onchocerca volvulus 0.0899 0.5117 1
Entamoeba histolytica SH2 domain containing protein 0.0528 0.2979 0.5821
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0112 0.0512
Brugia malayi Furin-like cysteine rich region family protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0227 0.3034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans hypothetical protein 0.0051 0.0227 0.3034
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi hypoxia-induced factor 1 0.0182 0.0984 0.1923
Schistosoma mansoni cpg binding protein 0.0015 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Onchocerca volvulus 0.0899 0.5117 1
Brugia malayi nuclear receptor RXR 0.0022 0.0058 0.0113
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0133 0.0614
Loa Loa (eye worm) TK/ROR protein kinase 0.0371 0.2071 0.4041
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0133 0.0614
Trichomonas vaginalis DNA polymerase eta, putative 0.0105 0.0539 0.2588
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.017 0.0323
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Echinococcus multilocularis receptor type guanylyl cyclase 0.0371 0.2071 0.2071
Plasmodium vivax tyrosine kinase-like protein, putative 0.0371 0.2071 1
Echinococcus multilocularis dnaJ subfamily B 0.0206 0.1118 0.1118
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Loa Loa (eye worm) hypothetical protein 0.0087 0.0436 0.0844
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Echinococcus granulosus tyrosine protein kinase Src42A 0.0528 0.2979 0.2979
Leishmania major DNA polymerase kappa, putative 0.002 0.0047 0.0193
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Leishmania major trypanothione reductase 0.0024 0.0069 0.0304
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0249 0.0479
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.017 0.0332
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0528 0.2979 0.5818
Loa Loa (eye worm) glutathione reductase 0.0024 0.0069 0.0127
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0371 0.2071 0.4041
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0019 0.0012
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0899 0.5117 0.5117
Onchocerca volvulus 0.0015 0.0019 0.0028
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0054 0.0245 0.3278
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.0564 0.0564
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0371 0.2071 0.2071
Onchocerca volvulus Cathepsin F homolog 0.0019 0.004 0.007
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Schistosoma mansoni DNA polymerase IV / kappa 0.002 0.0047 0.0047
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0155 0.0155
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0285 0.1349
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Plasmodium vivax protein kinase, putative 0.0371 0.2071 1
Brugia malayi Sex muscle abnormal protein 5 0.0528 0.2979 0.5821
Brugia malayi 6-phosphofructokinase 0.0055 0.0248 0.0484
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Loa Loa (eye worm) cytochrome P450 0.0013 0.0007 0.0004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus hypothetical protein 0.0528 0.2979 0.2979
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0227 0.3034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) doublecortin family protein 0.0013 0.0006 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Schistosoma mansoni suppressor of cytokine signaling 0.0528 0.2979 0.2979
Echinococcus granulosus tyrosine protein kinase pr2 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0371 0.2071 0.4041
Schistosoma mansoni inositol monophosphatase 0.0018 0.0036 0.0036
Loa Loa (eye worm) SRC-1 0.0899 0.5117 1
Trichomonas vaginalis glutaminase, putative 0.0133 0.0702 0.3375
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni rotamase 0.0036 0.0138 0.0138
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Toxoplasma gondii STE kinase 0.0371 0.2071 0.2065
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0054 0.0245 0.3278
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0899 0.5117 0.5117
Trichomonas vaginalis flap endonuclease-1, putative 0.0013 0.0008 0.0016
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) 6-phosphofructokinase 0.0055 0.0248 0.0475
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0371 0.2071 0.2071
Echinococcus multilocularis 6 phosphofructokinase 0.0055 0.0248 0.0248
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Schistosoma mansoni hypothetical protein 0.0031 0.0112 0.0112
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Echinococcus granulosus N chimaerin 0.0528 0.2979 0.2979
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0005 0.0009
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0258 0.0258
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0112 0.0106
Trypanosoma brucei chrX additional, unordered contigs 0.002 0.0047 0.0193
Echinococcus granulosus SHC transforming protein 3 0.0528 0.2979 0.2979
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.017 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Brugia malayi hypothetical protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0044 0.0078
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0112 0.0112
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.004 0.004
Brugia malayi nuclear receptor NHR-88 0.0019 0.0044 0.0087
Loa Loa (eye worm) 6-phosphofructokinase 0.0055 0.0248 0.0475
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0204 0.0197
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0138 0.0647
Entamoeba histolytica cysteine surface protein, putative 0.0371 0.2071 0.4047
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.017 0.017
Leishmania major DNA polymerase eta, putative 0.0091 0.0457 0.2181
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.0457 0.2181
Schistosoma mansoni cellular tumor antigen P53 0.0024 0.0072 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0058 0.0058
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Leishmania major DNA polymerase kappa, putative 0.0074 0.036 0.1708
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0044 0.0087
Schistosoma mansoni rab6-interacting 0.0013 0.0006 0.0006
Echinococcus granulosus NCK adaptor protein 0.0528 0.2979 0.2979
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0227 0.8074
Brugia malayi jmjC domain containing protein 0.0102 0.0521 0.1018
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) TK/ABL protein kinase 0.0899 0.5117 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0899 0.5117 0.5117
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0047 0.0193
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0528 0.2979 0.5818
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Trypanosoma brucei DNA polymerase eta, putative 0.0091 0.0457 0.2181
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0067 0.0317 0.0317
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi PHD-finger family protein 0.0031 0.0112 0.0219
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0242 0.0465
Echinococcus multilocularis tyrosine protein kinase 0.0371 0.2071 0.2071
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0074 0.036 0.1708
Loa Loa (eye worm) serine/threonine protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis set domain proteins, putative 0.0116 0.0601 0.2887
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi Cytochrome P450 family protein 0.0037 0.0147 0.0288
Toxoplasma gondii histone lysine methyltransferase SET1 0.0028 0.0093 0.0087
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0105 0.0539 0.2588
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0227 0.0444
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0528 0.2979 0.5821
Echinococcus multilocularis peregrin 0.0031 0.0112 0.0112
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0528 0.2979 0.2979
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0019 0.0044 0.0078
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0227 0.3034
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0249 0.0249
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica hypothetical protein, conserved 0.0371 0.2071 0.4047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0371 0.2071 0.4047
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0047 0.0193
Brugia malayi glutathione reductase 0.0024 0.0069 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Onchocerca volvulus 0.0015 0.0018 0.0027
Echinococcus granulosus FTZ F1 alpha 0.0041 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0019 0.0019
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0019 0.0019
Plasmodium falciparum protein kinase, putative 0.0371 0.2071 0.9986
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Echinococcus granulosus ephrin type A receptor 4 A 0.0371 0.2071 0.2071
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0112 0.0112
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.017 0.017
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0528 0.2979 0.2979
Echinococcus granulosus 6 phosphofructokinase 0.0055 0.0248 0.0248
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi bone morphogenetic protein type 1 receptor 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0155 0.0294
Mycobacterium ulcerans glutaminase 0.0133 0.0702 0.9558
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0371 0.2071 0.2071
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0047 0.0193
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi Tyrosine-protein kinase abl-1 0.0899 0.5117 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0015 0.0018 0.0047
Giardia lamblia DNA damage repair protein 0.002 0.0047 0.0188
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0227 0.3034
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0371 0.2071 0.4047
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0528 0.2979 0.2979
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.004 0.0079
Brugia malayi Thioredoxin reductase 0.0024 0.0069 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Loa Loa (eye worm) STAT protein 0.0528 0.2979 0.5818
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.017 0.0332
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Inositol-1 0.0018 0.0036 0.0071
Loa Loa (eye worm) hypothetical protein 0.0061 0.0285 0.0549
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0028
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.004 0.004
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0074 0.036 0.4852
Leishmania major DNA polymerase eta, putative 0.0047 0.0204 0.0953
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Brugia malayi SRC-1 0.0899 0.5117 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0021 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.017 0.017
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.0564 1
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0371 0.2071 0.9986
Giardia lamblia PHD finger protein 15 0.0031 0.0112 0.0505
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0113
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0019 0.0037
Echinococcus multilocularis SH2 domain containing protein 7 0.0528 0.2979 0.2979
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi cathepsin L-like precursor 0.0013 0.0005 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Brugia malayi hypothetical protein 0.0371 0.2071 0.4047
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus multilocularis Polycystic kidney disease protein 0.0013 0.0006 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Loa Loa (eye worm) TK/ACK protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.017 0.017
Toxoplasma gondii aldehyde dehydrogenase 0.0139 0.0734 0.0728
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0044 0.0044
Plasmodium falciparum amino acid transporter, putative 0.0019 0.004 0.016
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Schistosoma mansoni suppressor of cytokine signaling 0.0528 0.2979 0.2979
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0019 0.004 0.0163
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0304 0.0585
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0016 0.0025 0.0259
Brugia malayi integrin-linked kinase 0.0371 0.2071 0.4047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.004 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0528 0.2979 0.5818
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Brugia malayi hypothetical protein 0.0019 0.0044 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0019 0.004 0.007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Trichomonas vaginalis inositol monophosphatase, putative 0.0018 0.0036 0.0154
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Brugia malayi hypothetical protein 0.0019 0.004 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.004 0.0079
Echinococcus multilocularis tyrosine protein kinase shark 0.0899 0.5118 0.5118
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) inositol-1 0.0018 0.0036 0.0062
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0044 0.0087
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.017 0.017
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0015 0.0018 0.0063
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Schistosoma mansoni lipoxygenase 0.0056 0.0258 0.0258
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.017 0.0332
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0044 0.0044
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.004 0.004
Onchocerca volvulus 0.0109 0.0564 0.1094
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0147 0.0279
Loa Loa (eye worm) glutaminase 2 0.0133 0.0702 0.1364
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0055 0.0248 0.4211
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0019 0.017
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Brugia malayi SH2 domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0528 0.2979 0.2979
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0016 0.0026 0.0042
Loa Loa (eye worm) oxidoreductase 0.0015 0.0019 0.0028
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0019 0.004 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0734 0.0734
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0255 0.1203
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.004 0.0165 0.0165
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni hypothetical protein 0.0528 0.2979 0.2979
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.004 0.004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0242 0.0473
Schistosoma mansoni hypothetical protein 0.0039 0.0159 0.0159
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0031 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0249 0.0249
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0528 0.2979 0.2979
Toxoplasma gondii MAPEG family protein 0.1746 1 1
Echinococcus multilocularis heat shock protein 70 0.0371 0.2071 0.2071
Echinococcus multilocularis 0.0528 0.2979 0.2979
Mycobacterium ulcerans hypothetical protein 0.002 0.0047 0.055
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0371 0.2071 1
Schistosoma mansoni vav2 0.0528 0.2979 0.2979
Toxoplasma gondii ImpB/MucB/SamB family protein 0.002 0.0047 0.004
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) CXXC zinc finger family protein 0.0014 0.0016 0.0022
Echinococcus granulosus raf serine:threonine protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0013 0.0007 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0734 0.0734
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0153 0.0708
Echinococcus granulosus SH2 motif 0.0528 0.2979 0.2979
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni serine/threonine RGC 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus tumor protein p63 0.0165 0.0884 0.0884
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0242 0.0473
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Tyrosine-protein kinase PR2 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0899 0.5117 1
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Echinococcus granulosus activated cdc42 kinase 1 0.0371 0.2071 0.2071
Schistosoma mansoni inositol monophosphatase 0.0018 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0014 0.0016 0.0022
Echinococcus granulosus cytochrome P450 2K1 0.0013 0.0007 0.0007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Echinococcus multilocularis c src tyrosine kinase 0.0899 0.5117 0.5117
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0017 0.0033 0.0055
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0249 0.1175
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Brugia malayi ecdysone receptor 0.0019 0.0044 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Loa Loa (eye worm) hypothetical protein 0.0039 0.0156 0.0295
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0249 0.1175
Brugia malayi PAS domain containing protein 0.0059 0.0272 0.0532
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Plasmodium vivax vivapain-2 0.0019 0.004 0.0163
Brugia malayi steroid hormone receptor 0.0041 0.017 0.0332
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0019 0.004 0.0068
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0019 0.004 0.1629
Schistosoma mansoni hypothetical protein 0.0528 0.2979 0.2979
Echinococcus granulosus protein tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis tyrosine protein kinase Abl 0.0899 0.5117 0.5117
Plasmodium falciparum protein kinase, putative 0.0371 0.2074 1
Schistosoma mansoni tensin-related 0.0528 0.2979 0.2979
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0899 0.5117 0.5117
Onchocerca volvulus 0.0528 0.2979 0.5818
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TK family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0024 0.0069 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0899 0.5117 0.5117
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Toxoplasma gondii protein kinase 0.0371 0.2071 0.2065
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.017 0.0332
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Echinococcus multilocularis activated cdc42 kinase 1 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0529 0.2982 0.5827
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0021 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Echinococcus multilocularis tyrosine protein kinase pr2 0.0371 0.2071 0.2071
Loa Loa (eye worm) ctsf protein 0.0019 0.004 0.007
Echinococcus granulosus tensin 0.0528 0.2979 0.2979
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0249 0.117
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0371 0.2071 0.4041
Brugia malayi STAT protein, DNA binding domain containing protein 0.0528 0.2979 0.5821
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0031 0.0119
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Loa Loa (eye worm) serotonin transporter b 0.0109 0.0564 0.1094
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0528 0.2979 0.5818
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.004 0.004
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0153 1
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0053 0.0241 0.0462
Brugia malayi Flap endonuclease-1 0.0013 0.0008 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0078 0.0379 0.0733
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0015 0.0018 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0044 0.0044
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Plasmodium vivax glutathione reductase, putative 0.0024 0.0069 0.0305
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0249 0.1175
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0058 0.0104
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0343 0.1629
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0016 0.0025 0.069
Echinococcus multilocularis protein kinase 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis integrin linked protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0899 0.5117 0.5117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.017 0.017
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.017 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.0564 0.0564
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0044 0.0044
Schistosoma mansoni polycystin 1-related 0.0013 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) TK/INSR protein kinase 0.0371 0.2071 0.4041
Plasmodium falciparum transporter, putative 0.0019 0.004 0.016
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0021 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0044 0.0078
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0308 0.1456
Brugia malayi Cytochrome P450 family protein 0.0017 0.0031 0.0061
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0528 0.2979 0.2979
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0015 0.0018 0.0018
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0044 0.0044
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0249 0.0249
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Entamoeba histolytica protein kinase, putative 0.0529 0.2982 0.5827
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0019 0.017
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.017 0.017
Trichomonas vaginalis AGC family protein kinase 0.0371 0.2071 1
Brugia malayi Tensin 0.0528 0.2979 0.5821
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0371 0.2071 0.2071
Brugia malayi hypothetical protein 0.0022 0.0058 0.0113
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0371 0.2071 0.4041
Giardia lamblia Kinase 0.0371 0.2071 0.9998
Leishmania major hypothetical protein, conserved 0.0371 0.2071 0.9986
Echinococcus multilocularis tyrosine protein kinase HCK 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Plasmodium falciparum phd finger protein, putative 0.0031 0.0112 0.0511
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi nuclear receptor NHR-88 0.0041 0.017 0.0332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0153 0.2009
Mycobacterium tuberculosis Probable dehydrogenase 0.0054 0.0245 0.3278
Echinococcus multilocularis SHC transforming protein 3 0.0528 0.2979 0.2979
Mycobacterium leprae Possible regulatory protein 0.0015 0.0021 0.0515
Onchocerca volvulus 0.0044 0.0184 0.0351
Onchocerca volvulus 0.0899 0.5117 1
Plasmodium vivax amine transporter, putative 0.0019 0.004 0.016
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0019 0.017
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0091 0.0457 0.0886
Schistosoma mansoni nuclear hormone receptor 0.0041 0.017 0.017
Mycobacterium tuberculosis Probable oxidoreductase 0.006 0.028 0.3758
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Trypanosoma brucei unspecified product 0.0095 0.048 0.229
Onchocerca volvulus 0.0899 0.5117 1
Brugia malayi hypothetical protein 0.0087 0.0436 0.0852
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0058 0.0058
Schistosoma mansoni cpg binding protein 0.0015 0.002 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.017 0.0332
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0055 0.0248 0.3312
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0539 0.2577
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis dna polymerase kappa 0.0105 0.0539 0.0539
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0047 0.0193
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0015 0.0018 0.0012
Onchocerca volvulus 0.0019 0.0044 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0371 0.2071 1
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Schistosoma mansoni survival motor neuron protein 0.0039 0.0159 0.0159
Loa Loa (eye worm) glutaminase 0.0133 0.0702 0.1364
Echinococcus multilocularis signal transduction protein lnk realted 0.0528 0.2979 0.2979
Mycobacterium ulcerans putative regulatory protein 0.0044 0.0184 0.2436
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0133 0.0127
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0258 0.0258
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.017 0.017
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0242 0.114
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Schistosoma mansoni microsomal glutathione s-transferase 0.1746 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0138 0.0262
Toxoplasma gondii 6-phosphofructokinase 0.0015 0.0018 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0024 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) fibroinase 0.0019 0.004 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0019 0.0037
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.017 0.017
Echinococcus granulosus tyrosine protein kinase ABL1 0.0899 0.5117 0.5117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0112 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Onchocerca volvulus 0.0528 0.2979 0.5818
Echinococcus granulosus kinase suppressor of Ras 1 0.0371 0.2071 0.2071
Brugia malayi Cytochrome P450 family protein 0.0017 0.0031 0.0061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0005 0.0005
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0018 0.0036 0.003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.004 0.0163
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.017 0.0323
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Plasmodium falciparum glutathione reductase 0.0024 0.0069 0.0305
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) TK/ALK protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0899 0.5117 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0159 0.031
Onchocerca volvulus 0.0019 0.004 0.007
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0106 0.0099
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.004 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.017 0.0323
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0139 0.0734 0.0734
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0044 0.0078
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0899 0.5117 0.5117
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.004 0.004
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.017 0.0332
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.017 0.0332
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Echinococcus granulosus natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) cysteine protease 0.0019 0.004 0.007
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0528 0.2979 0.5818
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis protein tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0371 0.2071 0.4047
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0242 0.0242
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.017 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0285 0.1349
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.017 0.0323
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0112 0.021
Echinococcus multilocularis cysteine protease 0.0019 0.004 0.004
Brugia malayi 6-phosphofructokinase 0.0055 0.0248 0.0484
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0047 0.0193
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0044 0.0044
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0371 0.2071 0.4041
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0031 0.0339
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Brugia malayi Receptor family ligand binding region containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0021 0.0031
Echinococcus multilocularis inositol monophosphatase 1 0.0018 0.0036 0.0036
Echinococcus granulosus survival motor neuron protein 1 0.0193 0.1043 0.1043
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus SH2 domain containing protein 7 0.0528 0.2979 0.2979
Echinococcus multilocularis protein KINase family member (kin 25) 0.0371 0.2071 0.2071
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Plasmodium falciparum tyrosine kinase-like protein 0.0371 0.2071 0.9986
Brugia malayi hypothetical protein 0.0899 0.5117 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0249 0.1175
Brugia malayi Raf kinase 0.0371 0.2071 0.4047
Plasmodium vivax flap endonuclease 1, putative 0.0013 0.0008 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0521 0.0521
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Schistosoma mansoni thyroid hormone receptor 0.0041 0.017 0.017
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0528 0.2979 0.2979
Plasmodium vivax SET domain protein, putative 0.0015 0.0018 0.0057
Trypanosoma brucei Pseudokinase, putative 0.0371 0.2071 0.9986
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.03 0.03
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.017 0.0332
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0036 0.0154
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0021 0.0078
Echinococcus granulosus activin receptor type 0.0371 0.2074 0.2074
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0027
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.017 0.017
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Brugia malayi nuclear receptor NHR-67 0.0019 0.0044 0.0087
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0055 0.0248 0.8812
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Onchocerca volvulus 0.0015 0.0019 0.0028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0112 0.021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi hypothetical protein 0.0013 0.0006 0.0013
Echinococcus granulosus suppressor of cytokine signaling 6 0.0528 0.2979 0.2979
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0528 0.2979 0.2979
Schistosoma mansoni rab6-interacting 0.0013 0.0006 0.0006
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0371 0.2071 0.4047
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Onchocerca volvulus Cathepsin L homolog 0.0019 0.004 0.007
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0019 0.017
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0371 0.2071 0.2065
Echinococcus granulosus RUN 0.0013 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.017 0.0332
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0055 0.0248 0.1166
Loa Loa (eye worm) TK protein kinase 0.0899 0.5117 1
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0528 0.2979 0.2979
Echinococcus granulosus epidermal growth factor receptor 0.0371 0.2071 0.2071
Brugia malayi cytokine inducible SH2-containing protein 5 0.0528 0.2979 0.5821
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Echinococcus multilocularis cpg binding protein 0.0015 0.002 0.002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Toxoplasma gondii phosphofructokinase PFKII 0.0015 0.0018 0.0011
Onchocerca volvulus 0.0015 0.0019 0.0028
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.017 0.0323
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.017 0.017
Echinococcus granulosus expressed protein 0.0036 0.0138 0.0138
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Toxoplasma gondii hypothetical protein 0.0019 0.004 0.0033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0055 0.0248 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.017 0.0332
Echinococcus granulosus protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0019 0.007
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni cpg binding protein 0.0014 0.0016 0.0016
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.0453
Onchocerca volvulus 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0018 0.0036 0.5
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.0564 0.1102
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0371 0.2071 0.2071
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.0564 0.1094
Onchocerca volvulus 0.0019 0.004 0.007
Echinococcus granulosus growth factor receptor bound protein 2 0.0528 0.2979 0.2979
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0242 0.0242
Echinococcus granulosus cathepsin l1 0.0013 0.0005 0.0005
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0183 0.0988 0.1931
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Leishmania major DNA damage repair protein, putative 0.002 0.0047 0.0193
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Echinococcus granulosus dnaJ subfamily B 0.0206 0.1118 0.1118
Echinococcus multilocularis ephrin type A receptor 4 A 0.0371 0.2071 0.2071
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0044 0.0044
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Trypanosoma brucei unspecified product 0.0044 0.0186 0.0869
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni nck2/grb4 0.0528 0.2979 0.2979
Brugia malayi hypothetical protein 0.0022 0.0058 0.0113
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi hypothetical protein 0.0019 0.0044 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0018 0.0036 0.0071
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0899 0.5117 0.5117
Echinococcus granulosus signal transduction protein lnk realted 0.0528 0.2979 0.2979
Onchocerca volvulus 0.0019 0.004 0.007
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Schistosoma mansoni eyes absent homolog 0.0087 0.0436 0.0436
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Entamoeba histolytica cysteine protease, putative 0.0019 0.004 0.0079
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0021 0.0078
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.004 0.004
Trypanosoma cruzi protein kinase, putative 0.0371 0.2071 0.9986
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni lipoxygenase 0.0033 0.0124 0.0124
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.004 0.004
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0019 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0019 0.004 0.004
Onchocerca volvulus 0.0013 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Brugia malayi tailless protein 0.0019 0.0044 0.0087
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.0457 0.0894
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0227 0.3034
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Echinococcus granulosus tyrosine protein kinase Srms 0.0899 0.5117 0.5117
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0249 0.0243
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0015 0.0018 0.0034
Echinococcus granulosus tyrosine protein kinase HCK 0.0371 0.2071 0.2071
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0899 0.5117 0.5117
Echinococcus multilocularis activin receptor type 0.0371 0.2074 0.2074
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0899 0.5117 0.5117
Leishmania major protein kinase, putative 0.0371 0.2074 1
Onchocerca volvulus 0.0116 0.0601 0.1167
Echinococcus multilocularis tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis microsomal glutathione S transferase 3 0.1746 1 1
Brugia malayi MAP kinase sur-1 0.0055 0.0249 0.0487
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0521 0.0521
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0984 0.1915
Entamoeba histolytica ankyrin repeat protein 0.0371 0.2071 0.4047
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0019 0.017
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0371 0.2071 0.2065
Schistosoma mansoni shc transforming protein 0.0528 0.2979 0.2979
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.006 0.028 0.3758
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0019 0.017
Echinococcus multilocularis flap endonuclease 1 0.0013 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Echinococcus multilocularis raf serine:threonine protein kinase 0.0371 0.2071 0.2071
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0019 0.0453
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0019 0.0019
Brugia malayi nuclear hormone receptor 0.0041 0.017 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0041 0.017 0.0323
Onchocerca volvulus 0.0019 0.004 0.007
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0069 0.0304
Loa Loa (eye worm) TK/CSK protein kinase 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0039 0.0159 0.0302
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Brugia malayi C-terminal src kinase protein 1 0.0371 0.2071 0.4047
Plasmodium vivax vivapain-2 0.0019 0.004 0.0163
Brugia malayi Immunoglobulin I-set domain containing protein 0.0371 0.2071 0.4047
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.004 0.004
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Echinococcus multilocularis serotonin transporter 0.0109 0.0564 0.0564
Trypanosoma brucei protein kinase, putative 0.0055 0.0249 0.1175
Schistosoma mansoni jumonji domain containing protein 0.0081 0.04 0.04
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis expressed protein 0.0036 0.0138 0.0138
Loa Loa (eye worm) thioredoxin reductase 0.0024 0.0069 0.0127
Brugia malayi CXXC zinc finger family protein 0.0014 0.0016 0.0031
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.048 0.229
Brugia malayi phosphofructokinase 0.0055 0.0248 0.0484
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trypanosoma brucei protein kinase, putative 0.0371 0.2074 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Brugia malayi Pre-SET motif family protein 0.0015 0.0018 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0193 0.1043 0.203
Echinococcus granulosus dna polymerase kappa 0.0105 0.0539 0.0539
Trichomonas vaginalis STE family protein kinase 0.0371 0.2071 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Echinococcus granulosus SH2 motif 0.0528 0.2979 0.2979
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0018 0.0036 0.0409
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus histone lysine methyltransferase setb 0.0015 0.0018 0.0018
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0019 0.017
Toxoplasma gondii protein kinase domain-containing protein 0.0371 0.2071 0.2065
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0899 0.5117 0.5117
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0044 0.0044
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.017 0.0332
Echinococcus granulosus tyrosine protein kinase Lyn 0.09 0.512 0.512
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.017 0.0332
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0019 0.017
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0054 0.0245 0.3278
Plasmodium falciparum tyrosine kinase-like protein 0.0371 0.2071 0.9986
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.004 0.0163
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni growth factor receptor-bound protein 0.0528 0.2979 0.2979
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 308.1 nM Inhibition of [3H]-WIN- 35,428 binding to Dopamine transporter in rat striatal synaptic membranes ChEMBL. 11714614
IC50 (binding) = 308.1 nM Inhibition of [3H]-WIN- 35,428 binding to Dopamine transporter in rat striatal synaptic membranes ChEMBL. 11714614
Ratio (binding) = 2.84 Ratio of binding affinity of E isomer to that of Z isomer towards the dopamine transporter expressed as IC50(E)/IC50(Z) ChEMBL. 11714614
Ratio (binding) = 2.84 Ratio of binding affinity of E isomer to that of Z isomer towards the dopamine transporter expressed as IC50(E)/IC50(Z) ChEMBL. 11714614

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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