Detailed information for compound 175470

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 411.277 | Formula: C18H22INO2
  • H donors: 0 H acceptors: 1 LogP: 3.78 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: I/C=C/COC(=O)C1C2CCC(N2C)CC1c1ccccc1
  • InChi: 1S/C18H22INO2/c1-20-14-8-9-16(20)17(18(21)22-11-5-10-19)15(12-14)13-6-3-2-4-7-13/h2-7,10,14-17H,8-9,11-12H2,1H3/b10-5+
  • InChiKey: PTARSFHGDDMYOJ-BJMVGYQFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Dopamine transporter   619 aa 551 aa 39.9 %
Neospora caninum sodium-dependent transporter, putative Dopamine transporter   619 aa 498 aa 32.3 %
Schistosoma mansoni sodium/chloride dependent transporter Dopamine transporter   619 aa 588 aa 40.3 %
Onchocerca volvulus Dopamine transporter   619 aa 612 aa 23.5 %
Plasmodium vivax hypothetical protein, conserved Dopamine transporter   619 aa 657 aa 20.1 %
Echinococcus multilocularis sodium and chloride dependent glycine Dopamine transporter   619 aa 599 aa 41.9 %
Onchocerca volvulus Transmembrane protein 120 homolog Dopamine transporter   619 aa 578 aa 32.9 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 636 aa 31.8 %
Echinococcus granulosus sodium and chloride dependent glycine Dopamine transporter   619 aa 594 aa 41.4 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Dopamine transporter   619 aa 599 aa 44.2 %
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Dopamine transporter   619 aa 604 aa 37.9 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Dopamine transporter   619 aa 522 aa 36.0 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Dopamine transporter   619 aa 509 aa 40.1 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 578 aa 32.9 %
Schistosoma mansoni sodium/chloride dependent transporter Dopamine transporter   619 aa 558 aa 41.8 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Dopamine transporter   619 aa 557 aa 23.9 %
Brugia malayi Sodium:neurotransmitter symporter family protein Dopamine transporter   619 aa 578 aa 33.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0018 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0242 0.0242
Mycobacterium leprae Possible regulatory protein 0.0015 0.0021 0.0515
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/INSR protein kinase 0.0371 0.2071 0.4041
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0371 0.2071 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.017 0.0332
Echinococcus granulosus activated cdc42 kinase 1 0.0371 0.2071 0.2071
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0153 0.0709
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0528 0.2979 0.2979
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.017 0.0332
Plasmodium falciparum protein kinase, putative 0.0371 0.2074 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.006 0.028 0.3758
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0528 0.2979 0.5818
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Brugia malayi nuclear receptor RXR 0.0022 0.0058 0.0113
Echinococcus granulosus tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus inositol monophosphatase 1 0.0018 0.0036 0.0036
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0371 0.2071 0.2065
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus cathepsin l1 0.0013 0.0005 0.0005
Onchocerca volvulus Cathepsin L homolog 0.0019 0.004 0.007
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0139 0.0734 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.017 0.017
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Brugia malayi ecdysteroid receptor 0.0041 0.017 0.0332
Loa Loa (eye worm) flap endonuclease-1 0.0013 0.0008 0.0006
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0371 0.2071 0.2071
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.017 0.017
Schistosoma mansoni lipoxygenase 0.0033 0.0124 0.0124
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0044 0.0044
Trypanosoma brucei DNA polymerase eta, putative 0.0091 0.0457 0.2181
Echinococcus granulosus receptor type guanylyl cyclase 0.0371 0.2071 0.2071
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0528 0.2979 0.5818
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0019 0.004 0.007
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0528 0.2979 0.2979
Giardia lamblia Protein 21.1 0.0371 0.2071 0.9998
Loa Loa (eye worm) TK/RYK protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Leishmania major cysteine peptidase A (CPA) 0.0019 0.004 0.0163
Schistosoma mansoni serine/threonine RGC 0.0371 0.2071 0.2071
Brugia malayi hypothetical protein 0.0019 0.004 0.0077
Giardia lamblia DNA damage repair protein 0.002 0.0047 0.0188
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0155 0.0155
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Brugia malayi tailless protein 0.0019 0.0044 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0019 0.0044 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0021 0.0021
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0242 0.0242
Echinococcus granulosus N chimaerin 0.0528 0.2979 0.2979
Schistosoma mansoni thyroid hormone receptor 0.0041 0.017 0.017
Brugia malayi glutathione reductase 0.0024 0.0069 0.0136
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0021 0.0078
Brugia malayi hypothetical protein 0.0198 0.1072 0.2095
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0249 0.0249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.017 0.017
Plasmodium vivax vivapain-2 0.0019 0.004 0.0163
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.004 0.0163
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0371 0.2074 0.2068
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.0564 0.1094
Onchocerca volvulus 0.0899 0.5117 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni cytochrome P450 0.0013 0.0007 0.0007
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Mycobacterium ulcerans putative regulatory protein 0.0044 0.0184 0.2436
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0371 0.2071 1
Schistosoma mansoni microsomal glutathione s-transferase 0.1746 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis growth factor receptor bound protein 2 0.0528 0.2979 0.2979
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0044 0.0087
Schistosoma mansoni nuclear receptor 0.0019 0.0044 0.0044
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0044 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) phosphofructokinase 0.0055 0.0248 0.0475
Trypanosoma brucei Flagellum attachment zone protein 20 0.0371 0.2071 0.9986
Giardia lamblia Kinase, NEK 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0015 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0041 0.017 0.017
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0019 0.017
Trichomonas vaginalis set domain proteins, putative 0.0116 0.0601 0.2887
Trypanosoma brucei Pseudokinase, putative 0.0371 0.2071 0.9986
Loa Loa (eye worm) cysteine protease 0.0019 0.004 0.007
Onchocerca volvulus 0.0528 0.2979 0.5818
Echinococcus multilocularis activin receptor type 0.0371 0.2074 0.2074
Echinococcus multilocularis tyrosine kinase 0.0899 0.5117 0.5117
Onchocerca volvulus 0.0019 0.004 0.007
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi nuclear receptor NHR-88 0.0019 0.0044 0.0087
Echinococcus multilocularis receptor type guanylyl cyclase 0.0371 0.2071 0.2071
Brugia malayi Pre-SET motif family protein 0.0102 0.052 0.1016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Onchocerca volvulus 0.0019 0.004 0.007
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) inositol-1 0.0018 0.0036 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0044 0.0044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0015 0.0018 0.0018
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0021 0.0068
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0371 0.2071 0.4047
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.017 0.017
Brugia malayi hypoxia-induced factor 1 0.0182 0.0984 0.1923
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.004 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni hypothetical protein 0.0031 0.0112 0.0112
Echinococcus multilocularis dnaJ subfamily B 0.0206 0.1118 0.1118
Loa Loa (eye worm) TK/EGFR protein kinase 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0019 0.004 0.0068
Mycobacterium ulcerans hypothetical protein 0.002 0.0047 0.055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0055 0.0248 0.3312
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0159 0.031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0028
Echinococcus multilocularis kinase suppressor of Ras 1 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0019 0.017
Entamoeba histolytica hypothetical protein, conserved 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0899 0.5117 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0004
Schistosoma mansoni flap endonuclease-1 0.0012 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.0074 0.036 0.1705
Toxoplasma gondii protein kinase domain-containing protein 0.0371 0.2071 0.2065
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0112 0.0106
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0058 0.0058
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0005 0.0005
Brugia malayi Inositol-1 0.0018 0.0036 0.0071
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Echinococcus multilocularis signal transduction protein lnk realted 0.0528 0.2979 0.2979
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.004 0.0163
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0528 0.2979 0.5818
Echinococcus granulosus tyrosine kinase 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0039 0.0156 0.0295
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0019 0.0012
Onchocerca volvulus 0.0044 0.0184 0.0351
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0036 0.0154
Echinococcus granulosus tyrosine protein kinase Src42A 0.0528 0.2979 0.2979
Schistosoma mansoni inositol monophosphatase 0.0018 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0019 0.017
Echinococcus multilocularis protein KINase family member (kin 25) 0.0371 0.2071 0.2071
Echinococcus multilocularis tumor protein p63 0.0165 0.0884 0.0884
Onchocerca volvulus 0.0013 0.0006 0.0004
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.004 0.004
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0044 0.0087
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0044 0.0078
Echinococcus multilocularis thioredoxin glutathione reductase 0.0024 0.0069 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0528 0.2979 0.5818
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus insulin receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) ctsf protein 0.0019 0.004 0.007
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0371 0.2071 0.4041
Giardia lamblia Kinase, NEK 0.0371 0.2071 0.9998
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0044 0.0044
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi jmjC domain containing protein 0.0102 0.0521 0.1018
Echinococcus multilocularis expressed protein 0.0036 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0019 0.0037
Trichomonas vaginalis inositol monophosphatase, putative 0.0018 0.0036 0.0154
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Brugia malayi cytokine inducible SH2-containing protein 5 0.0528 0.2979 0.5821
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0112 0.0112
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.017 0.017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Schistosoma mansoni hypothetical protein 0.0371 0.2071 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0018 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus tyrosine protein kinase Src42A 0.0899 0.5117 0.5117
Schistosoma mansoni single-minded 0.0059 0.0272 0.0272
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.004 0.004
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0044 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0047 0.0193
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Plasmodium falciparum phd finger protein, putative 0.0031 0.0112 0.0511
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0153 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0249 0.1175
Loa Loa (eye worm) TK/FAK protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis tyrosine protein kinase Blk 0.0899 0.5117 0.5117
Toxoplasma gondii histone lysine methyltransferase SET1 0.0028 0.0093 0.0087
Loa Loa (eye worm) glutathione reductase 0.0024 0.0069 0.0127
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis dna polymerase kappa 0.0105 0.0539 0.0539
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi phosphofructokinase 0.0055 0.0248 0.0484
Schistosoma mansoni polycystin 1-related 0.0013 0.0006 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.03 0.4038
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.004 0.0163
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0249 0.117
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0285 0.1349
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Loa Loa (eye worm) hypothetical protein 0.0198 0.1072 0.2088
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Trichomonas vaginalis protein kinase atn1, putative 0.0371 0.2071 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.004 0.004
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Entamoeba histolytica cysteine surface protein, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) SRC-1 0.0899 0.5117 1
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Brugia malayi 6-phosphofructokinase 0.0055 0.0248 0.0484
Echinococcus granulosus expressed conserved protein 0.0528 0.2979 0.2979
Brugia malayi Cytochrome P450 family protein 0.0017 0.0031 0.0061
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0019 0.0453
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Echinococcus granulosus growth factor receptor bound protein 2 0.0528 0.2979 0.2979
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0018 0.0053
Brugia malayi STAT protein, DNA binding domain containing protein 0.0528 0.2979 0.5821
Loa Loa (eye worm) doublecortin family protein 0.0013 0.0006 0.0004
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.017 0.0332
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.017 0.0332
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0528 0.2979 0.2979
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.017 0.0323
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0019 0.0012
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0016 0.0025 0.0259
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Onchocerca volvulus 0.0899 0.5117 1
Plasmodium falciparum flap endonuclease 1 0.0013 0.0008 0.0007
Schistosoma mansoni tyrosine protein kinase 0.0371 0.2071 0.2071
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0227 0.3034
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Tensin 0.0528 0.2979 0.5821
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0899 0.5117 0.5117
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0014 0.0013 0.0013
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0371 0.2071 0.2071
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Schistosoma mansoni nck2/grb4 0.0528 0.2979 0.2979
Brugia malayi Cytochrome P450 family protein 0.0017 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0139 0.0734 0.0734
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0343 0.1629
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0984 0.1915
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus cpg binding protein 0.0015 0.002 0.002
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.017 0.017
Echinococcus multilocularis flap endonuclease 1 0.0013 0.0008 0.0008
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0019 0.004 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0113
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Schistosoma mansoni rab6-interacting 0.0013 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0015 0.0018 0.0011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.017 0.017
Echinococcus multilocularis tyrosine protein kinase pr2 0.0371 0.2071 0.2071
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0539 0.2577
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0019 0.017
Echinococcus granulosus signal transduction protein lnk realted 0.0528 0.2979 0.2979
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus tumor protein p63 0.0165 0.0884 0.0884
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Toxoplasma gondii phosphofructokinase PFKII 0.0015 0.0018 0.0011
Schistosoma mansoni eyes absent homolog 0.0087 0.0436 0.0436
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Echinococcus granulosus integrin linked protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis protein tyrosine kinase, putative 0.0371 0.2071 1
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0153 0.0708
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Onchocerca volvulus Cathepsin F homolog 0.0019 0.004 0.007
Echinococcus granulosus dna polymerase kappa 0.0105 0.0539 0.0539
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0153 0.2009
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis NCK adaptor protein 0.0528 0.2979 0.2979
Onchocerca volvulus 0.0016 0.0026 0.0042
Brugia malayi polk-prov protein 0.0061 0.0285 0.0558
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0044 0.0078
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0193 0.1043 0.203
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0019 0.017
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0528 0.2979 0.2979
Onchocerca volvulus 0.0015 0.0019 0.0028
Brugia malayi Furin-like cysteine rich region family protein 0.0371 0.2071 0.4047
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0371 0.2071 0.4041
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0105 0.0539 0.2588
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0112 0.0106
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Echinococcus granulosus tyrosine kinase 0.0899 0.5117 0.5117
Brugia malayi hypothetical protein 0.0899 0.5117 1
Echinococcus multilocularis cysteine protease 0.0019 0.004 0.004
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Plasmodium falciparum amino acid transporter, putative 0.0019 0.004 0.016
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0272 0.0272
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0528 0.2979 0.2979
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus multilocularis 6 phosphofructokinase 0.0055 0.0248 0.0248
Onchocerca volvulus 0.0039 0.0159 0.0302
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus thioredoxin glutathione reductase 0.0024 0.0069 0.0069
Trypanosoma brucei unspecified product 0.0095 0.048 0.229
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Leishmania major protein kinase, putative 0.0371 0.2074 1
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.004 0.004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.017 0.0332
Brugia malayi cytochrome P450 0.0013 0.0007 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0019 0.004 0.0068
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0044 0.0044
Loa Loa (eye worm) fibroinase 0.0019 0.004 0.007
Echinococcus granulosus protein kinase 0.0371 0.2071 0.2071
Schistosoma mansoni nuclear hormone receptor 0.0041 0.017 0.017
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Schistosoma mansoni nuclear receptor 0.0019 0.0044 0.0044
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0018 0.0036 0.0409
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0044 0.0078
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0528 0.2979 0.2979
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.0564 0.1102
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Onchocerca volvulus 0.0015 0.0018 0.0027
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi PAS domain containing protein 0.0059 0.0272 0.0532
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.017 0.0323
Echinococcus multilocularis Polycystic kidney disease protein 0.0013 0.0006 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.0453
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0019 0.017
Plasmodium vivax SET domain protein, putative 0.0015 0.0018 0.0057
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0204 0.0197
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Brugia malayi hypothetical protein 0.0019 0.0044 0.0087
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0044 0.0087
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0155 0.0155
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0047 0.0193
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0153 0.2009
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0528 0.2979 0.5818
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Onchocerca volvulus 0.0024 0.0072 0.0131
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Brugia malayi Receptor family ligand binding region containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0019 0.0453
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0019 0.0037
Trypanosoma cruzi protein kinase, putative 0.0371 0.2071 0.9986
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0112 0.0512
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Plasmodium vivax glutathione reductase, putative 0.0024 0.0069 0.0305
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0013 0.0008 0.0001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0074 0.036 0.1708
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0371 0.2071 0.2071
Schistosoma mansoni suppressor of cytokine signaling 0.0528 0.2979 0.2979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0019 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.006 0.028 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0242 0.0242
Brugia malayi bHLH-PAS transcription factor 0.0044 0.0184 0.0359
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi SRC-1 0.0899 0.5117 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0031 0.0339
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi integrin-linked kinase 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0899 0.5117 0.5117
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0255 0.1203
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0055 0.0248 0.1166
Echinococcus multilocularis c src tyrosine kinase 0.0899 0.5117 0.5117
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0138 0.0647
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni 6-phosphofructokinase 0.0055 0.0248 0.0248
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Echinococcus multilocularis RUN 0.0013 0.0006 0.0006
Mycobacterium ulcerans 6-phosphofructokinase 0.0055 0.0248 0.3312
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Loa Loa (eye worm) STAT protein 0.0528 0.2979 0.5818
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.004 0.004
Trypanosoma cruzi protein kinase, putative 0.0371 0.2071 0.9986
Loa Loa (eye worm) TK/Met protein kinase 0.0371 0.2071 0.4041
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0242 0.114
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0457 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0249 0.0249
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0036 0.0154
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0528 0.2979 0.5821
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi nuclear receptor NHR-88 0.0041 0.017 0.0332
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.017 0.0323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0734 0.0734
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0047 0.0193
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.017 0.017
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0528 0.2979 0.2979
Brugia malayi hypothetical protein 0.0371 0.2071 0.4047
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0015 0.0018 0.0063
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0133 0.0127
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Schistosoma mansoni cellular tumor antigen P53 0.0024 0.0072 0.0072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0019 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0058 0.0058
Echinococcus granulosus hypothetical protein 0.0528 0.2979 0.2979
Loa Loa (eye worm) CXXC zinc finger family protein 0.0014 0.0016 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0139 0.0734 0.0734
Brugia malayi nuclear receptor RXR 0.0019 0.0044 0.0087
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.004 0.004
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0285 0.1349
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis glutaminase, putative 0.0133 0.0702 0.3375
Loa Loa (eye worm) serine/threonine protein kinase 0.0371 0.2071 0.4041
Giardia lamblia PHD finger protein 15 0.0031 0.0112 0.0505
Echinococcus multilocularis protein kinase 0.0371 0.2071 0.2071
Schistosoma mansoni inositol monophosphatase 0.0018 0.0036 0.0036
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0371 0.2071 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0042 0.0042
Brugia malayi Sex muscle abnormal protein 5 0.0528 0.2979 0.5821
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0528 0.2979 0.5818
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0018 0.0053
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0044 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.004 0.004
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Plasmodium vivax amine transporter, putative 0.0019 0.004 0.016
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0528 0.2979 0.2979
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0371 0.2071 0.2071
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0204 0.0953
Echinococcus granulosus cytochrome P450 2K1 0.0013 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0051 0.0227 0.0436
Brugia malayi RhoGAP domain containing protein 0.0528 0.2979 0.5821
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0528 0.2979 0.2979
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.017 0.0332
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Plasmodium falciparum thioredoxin reductase 0.0024 0.0069 0.0305
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.0457 0.2181
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trichomonas vaginalis AGC family protein kinase 0.0371 0.2071 1
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis inositol monophosphatase 1 0.0018 0.0036 0.0036
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0183 0.0988 0.1931
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0371 0.2071 0.4047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.017 0.0332
Loa Loa (eye worm) hypothetical protein 0.0899 0.5117 1
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.017 0.017
Brugia malayi nuclear hormone receptor 0.0041 0.017 0.0332
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0258 0.0258
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0371 0.2071 1
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0112 0.0112
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0078 0.0379 0.0733
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0047 0.0193
Echinococcus granulosus tensin 0.0528 0.2979 0.2979
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0227 0.3034
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.004 0.0077
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.0021 0.0232
Schistosoma mansoni DNA polymerase IV / kappa 0.002 0.0047 0.0047
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Echinococcus multilocularis survival motor neuron protein 1 0.0193 0.1043 0.1043
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Schistosoma mansoni DNA polymerase eta 0.0091 0.0457 0.0457
Brugia malayi Cytochrome P450 family protein 0.0037 0.0147 0.0288
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Onchocerca volvulus 0.0371 0.2071 0.4041
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0133 0.0614
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.015 0.015
Echinococcus multilocularis dna polymerase eta 0.0091 0.0457 0.0457
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0019 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0528 0.2979 0.5818
Entamoeba histolytica receptor protein kinase, putative 0.0371 0.2071 0.4047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0044 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0371 0.2071 0.2071
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0021 0.0078
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0036 0.0144
Echinococcus multilocularis integrin linked protein kinase 0.0371 0.2071 0.2071
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0371 0.2074 0.2074
Echinococcus granulosus serotonin transporter 0.0109 0.0564 0.0564
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0899 0.5117 1
Schistosoma mansoni GTPase activating protein 0.0528 0.2979 0.2979
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0183 0.0183
Loa Loa (eye worm) TK protein kinase 0.0899 0.5117 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0155 0.0294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.017 0.0332
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0371 0.2071 0.4047
Brugia malayi nuclear hormone receptor 0.0019 0.0044 0.0087
Leishmania major ATP-dependent phosphofructokinase 0.0055 0.0248 0.1166
Loa Loa (eye worm) TK/ROR protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis cysteine protease 0.0019 0.004 0.004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0018 0.0036 0.5
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0054 0.0245 0.3278
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.017 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2074 0.4052
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.017 0.0332
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0899 0.5117 0.5117
Plasmodium vivax tyrosine kinase-like protein, putative 0.0371 0.2071 1
Echinococcus granulosus FTZ F1 alpha 0.0041 0.017 0.017
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.004 0.004
Brugia malayi Raf kinase 0.0371 0.2071 0.4047
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0227 0.0444
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Leishmania major protein kinase, putative 0.0371 0.2071 0.9986
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) TK/EPH protein kinase 0.0371 0.2071 0.4041
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0031 0.0052
Echinococcus granulosus fibroblast growth factor receptor 4 0.0371 0.2071 0.2071
Entamoeba histolytica phosphofructokinase, putative 0.0055 0.0248 0.0484
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0249 0.1175
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni shc transforming protein 0.0528 0.2979 0.2979
Toxoplasma gondii protein kinase 0.0371 0.2071 0.2065
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0113
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0031 0.0119
Loa Loa (eye worm) hypothetical protein 0.0061 0.0285 0.0549
Schistosoma mansoni survival motor neuron protein 0.0039 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni zinc finger protein 0.0019 0.0044 0.0044
Entamoeba histolytica SH2 domain containing protein 0.0528 0.2979 0.5821
Echinococcus multilocularis SHC transforming protein 3 0.0528 0.2979 0.2979
Echinococcus multilocularis heat shock protein 70 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0015 0.0021 0.0031
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0005 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.004 0.004
Schistosoma mansoni signal transduction protein lnk-related 0.0528 0.2979 0.2979
Plasmodium falciparum protein kinase, putative 0.0371 0.2071 0.9986
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi hypothetical protein 0.0013 0.0006 0.0013
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Toxoplasma gondii hypothetical protein 0.0019 0.004 0.0033
Echinococcus multilocularis FL cytokine receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0087 0.0436 0.0844
Echinococcus multilocularis 0.0013 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Leishmania major DNA polymerase eta, putative 0.0047 0.0204 0.0953
Echinococcus multilocularis tyrosine protein kinase 0.0371 0.2071 0.2071
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Trichomonas vaginalis STE family protein kinase 0.0371 0.2071 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0015 0.0018 0.0012
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Echinococcus granulosus c src tyrosine kinase 0.0899 0.5117 0.5117
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Brugia malayi hypothetical protein 0.0019 0.0044 0.0087
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.004 0.004
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Echinococcus multilocularis N chimaerin 0.0528 0.2979 0.2979
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0138 0.0262
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0371 0.2071 0.9986
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0734 1
Leishmania major hypothetical protein, conserved 0.0371 0.2071 0.9986
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0899 0.5117 1
Schistosoma mansoni SH2A 0.0528 0.2979 0.2979
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0021 0.0078
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0371 0.2071 0.2071
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Onchocerca volvulus 0.0371 0.2071 0.4041
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.036 0.1708
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis insulin receptor 0.0371 0.2071 0.2071
Echinococcus granulosus Polycystic kidney disease protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Brugia malayi cathepsin L-like precursor 0.0013 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica ankyrin repeat protein 0.0371 0.2071 0.4047
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0528 0.2979 0.2979
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus multilocularis protein kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis tensin 0.0528 0.2979 0.2979
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0109 0.0564 0.1094
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus SH2 motif 0.0528 0.2979 0.2979
Plasmodium vivax protein kinase, putative 0.0371 0.2071 1
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0227 0.0444
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0249 0.0249
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0019 0.004 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.017 0.0323
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.004 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Onchocerca volvulus 0.0013 0.0006 0.0004
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0371 0.2071 0.2065
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0371 0.2071 0.4041
Loa Loa (eye worm) serotonin transporter b 0.0109 0.0564 0.1094
Leishmania major protein kinase, putative 0.0016 0.0024 0.0082
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.017 0.017
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0528 0.2979 0.2979
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0054 0.0245 0.3278
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0055 0.0248 0.8812
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Entamoeba histolytica receptor protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0019 0.0037
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.0564 1
Entamoeba histolytica cysteine protease, putative 0.0019 0.004 0.0079
Brugia malayi Bromodomain containing protein 0.0031 0.0112 0.0219
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis cpg binding protein 0.0015 0.002 0.002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Schistosoma mansoni cpg binding protein 0.0014 0.0016 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Brugia malayi SH2 domain containing protein 0.0899 0.5117 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0899 0.5117 0.5117
Echinococcus multilocularis tensin 0.0528 0.2979 0.2979
Plasmodium falciparum protein kinase, putative 0.0371 0.2071 0.9986
Mycobacterium tuberculosis Probable oxidoreductase 0.006 0.028 0.3758
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Flap endonuclease-1 0.0013 0.0008 0.0015
Schistosoma mansoni lipoxygenase 0.0056 0.0258 0.0258
Echinococcus multilocularis tyrosine protein kinase Abl 0.0899 0.5117 0.5117
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.004 0.004
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0047 0.0193
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi hypothetical protein 0.0087 0.0436 0.0852
Echinococcus multilocularis tyrosine protein kinase Srms 0.0899 0.5117 0.5117
Brugia malayi nuclear receptor NHR-67 0.0019 0.0044 0.0087
Onchocerca volvulus 0.0371 0.2071 0.4041
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Brugia malayi bone morphogenetic protein type 1 receptor 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi hypothetical protein 0.0193 0.1043 0.2037
Echinococcus multilocularis protein tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.004 0.0173
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Brugia malayi Immunoglobulin I-set domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0528 0.2979 0.2979
Giardia lamblia Kinase 0.0371 0.2071 0.9998
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0249 0.1175
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0019 0.004 0.007
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0021 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Echinococcus multilocularis tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) thioredoxin reductase 0.0024 0.0069 0.0127
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0371 0.2071 0.4041
Trypanosoma brucei trypanothione reductase 0.0024 0.0069 0.0304
Echinococcus granulosus SHC transforming protein 3 0.0528 0.2979 0.2979
Schistosoma mansoni vav2 0.0528 0.2979 0.2979
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0021 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Echinococcus multilocularis nuclear factor of activated T cells 5 0.004 0.0165 0.0165
Echinococcus granulosus flap endonuclease 1 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0106 0.0099
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0024 0.0082
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0024 0.0069 0.0864
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0015 0.0018 0.0034
Echinococcus granulosus SH2 domain containing adapter protein F 0.0528 0.2979 0.2979
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0249 0.0479
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0308 0.1456
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi PHD-finger family protein 0.0031 0.0112 0.0219
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0899 0.5117 0.5117
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.0564 0.1094
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.004 0.004
Brugia malayi SH2 domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0899 0.5117 0.5117
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Schistosoma mansoni cpg binding protein 0.0015 0.002 0.002
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0015 0.0018 0.0018
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0436 0.0844
Brugia malayi Thioredoxin reductase 0.0024 0.0069 0.0136
Trichomonas vaginalis DNA polymerase eta, putative 0.0105 0.0539 0.2588
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0112 0.0112
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.017 0.017
Echinococcus granulosus dnaJ subfamily B 0.0206 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK/CSK protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine protein kinase Srms 0.0899 0.5117 0.5117
Echinococcus multilocularis transfer RNA-Lys 0.0044 0.0184 0.0184
Echinococcus multilocularis epidermal growth factor receptor 0.0371 0.2071 0.2071
Brugia malayi steroid hormone receptor 0.0041 0.017 0.0332
Leishmania major trypanothione reductase 0.0024 0.0069 0.0304
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0528 0.2979 0.5818
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.017 0.0332
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0227 0.0436
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Schistosoma mansoni tyrosine kinase 0.0899 0.5118 0.5118
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.017 0.0323
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0227 0.3034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Echinococcus multilocularis serotonin transporter 0.0109 0.0564 0.0564
Loa Loa (eye worm) oxidoreductase 0.0015 0.0019 0.0028
Echinococcus multilocularis tyrosine protein kinase HCK 0.0371 0.2071 0.2071
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0249 0.1175
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0227 0.8074
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0227 0.0444
Leishmania major DNA polymerase kappa, putative 0.002 0.0047 0.0193
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.006 0.028 0.3758
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0249 0.0249
Loa Loa (eye worm) 6-phosphofructokinase 0.0055 0.0248 0.0475
Trypanosoma brucei unspecified product 0.0044 0.0186 0.0869
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.004 0.0079
Schistosoma mansoni 6-phosphofructokinase 0.0055 0.0248 0.0248
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0521 0.0521
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Mycobacterium tuberculosis Probable reductase 0.0054 0.0245 0.3278
Schistosoma mansoni protein tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus multilocularis natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Onchocerca volvulus 0.0019 0.0044 0.0078
Leishmania major DNA polymerase eta, putative 0.0091 0.0457 0.2181
Onchocerca volvulus 0.0371 0.2071 0.4041
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.017 0.017
Brugia malayi Guanylyl cyclase protein 23 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Brugia malayi conserved hypotetical protein 0.0019 0.0044 0.0087
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0529 0.2982 0.5827
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.03 0.03
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0899 0.5117 0.5117
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0133 0.0614
Loa Loa (eye worm) TK/ACK protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.0528 0.2979 0.2979
Echinococcus granulosus SH2 motif 0.0528 0.2979 0.2979
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Trypanosoma brucei unspecified product 0.0044 0.0186 0.0869
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0104
Plasmodium vivax thioredoxin reductase, putative 0.0024 0.0069 0.0305
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.004 0.0163
Plasmodium vivax hypothetical protein, conserved 0.0019 0.004 0.016
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0112 0.0112
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0371 0.2071 0.2071
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0019 0.004 0.007
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0183 0.0183
Brugia malayi hypothetical protein 0.0022 0.0058 0.0113
Schistosoma mansoni ephrin receptor 0.0371 0.2071 0.2071
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0055 0.0248 0.4211
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0304 0.0585
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0227 0.3034
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0227 0.0444
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0899 0.5117 0.5117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.017 0.0323
Trichomonas vaginalis phosphofructokinase, putative 0.0055 0.0248 0.1176
Toxoplasma gondii thioredoxin reductase 0.0024 0.0069 0.0063
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0047 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0371 0.2071 0.4047
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.03 0.03
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Loa Loa (eye worm) TK/ABL protein kinase 0.0899 0.5117 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0249 0.1175
Brugia malayi Tyrosine-protein kinase PR2 0.0371 0.2071 0.4047
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.004 0.004
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Brugia malayi 6-phosphofructokinase 0.0055 0.0248 0.0484
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0539 0.732
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0044 0.0044
Onchocerca volvulus Tyrosine kinase homolog 0.0371 0.2071 0.4041
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0112 0.021
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0069 0.0304
Echinococcus granulosus tyrosine protein kinase Blk 0.0899 0.5117 0.5117
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0242 0.0465
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.004 0.004
Onchocerca volvulus 0.0528 0.2979 0.5818
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Echinococcus granulosus tyrosine protein kinase shark 0.0899 0.5118 0.5118
Toxoplasma gondii STE kinase 0.0371 0.2071 0.2065
Leishmania major DNA polymerase kappa, putative 0.0074 0.036 0.1708
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.03 0.0587
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus suppressor of cytokine signaling 6 0.0528 0.2979 0.2979
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0112 0.0112
Echinococcus granulosus tyrosine protein kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) cytochrome P450 0.0013 0.0007 0.0004
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis transfer RNA-Thr 0.0371 0.2071 0.2071
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.017 0.0323
Onchocerca volvulus Alhambra homolog 0.0031 0.0112 0.021
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0371 0.2074 0.2074
Schistosoma mansoni hypothetical protein 0.0528 0.2979 0.2979
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.017 0.017
Schistosoma mansoni suppressor of cytokine signaling 0.0528 0.2979 0.2979
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0068
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0133 0.0261
Toxoplasma gondii 6-phosphofructokinase 0.0015 0.0018 0.0011
Trichomonas vaginalis flap endonuclease-1, putative 0.0013 0.0008 0.0016
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Loa Loa (eye worm) protein kinase domain-containing protein 0.0371 0.2071 0.4041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Plasmodium falciparum DNA repair protein REV1, putative 0.002 0.0047 0.0194
Plasmodium vivax tyrosine kinase-like protein, putative 0.0371 0.2071 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.002 0.0047 0.004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0112 0.0112
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.048 0.229
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0227 0.1068
Trichomonas vaginalis rotamase, putative 0.0035 0.0133 0.0624
Echinococcus granulosus peregrin 0.0031 0.0112 0.0112
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.03 0.03
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.03 0.0579
Plasmodium falciparum tyrosine kinase-like protein 0.0371 0.2071 0.9986
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0019 0.017
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.1746 1 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Loa Loa (eye worm) glutaminase 2 0.0133 0.0702 0.1364
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.017 0.0332
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Schistosoma mansoni rotamase 0.0036 0.0138 0.0138
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0539 0.2577
Leishmania major DNA damage repair protein, putative 0.002 0.0047 0.0193
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0019 0.004 0.004
Echinococcus granulosus natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0371 0.2071 0.2071
Echinococcus multilocularis ephrin type A receptor 4 A 0.0371 0.2071 0.2071
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.2071 0.2071
Brugia malayi ecdysone receptor 0.0019 0.0044 0.0087
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Brugia malayi Cytochrome P450 family protein 0.0013 0.0007 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.017 0.0332
Schistosoma mansoni growth factor receptor-bound protein 0.0528 0.2979 0.2979
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0147 0.0279
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0068
Onchocerca volvulus 0.0019 0.004 0.007
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0112 0.021
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0528 0.2979 0.5818
Brugia malayi Tyrosine-protein kinase abl-1 0.0899 0.5117 1
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0044 0.0087
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0371 0.2071 0.2071
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0899 0.5117 0.5117
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0044 0.0087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0227 0.3034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0028
Echinococcus granulosus activin receptor type 0.0371 0.2074 0.2074
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0013 0.0007 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.017 0.017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Entamoeba histolytica Flap nuclease, putative 0.0013 0.0008 0.0015
Onchocerca volvulus 0.0899 0.5117 1
Brugia malayi protein-tyrosine kinase 0.0899 0.5117 1
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Echinococcus granulosus epidermal growth factor receptor 0.0371 0.2071 0.2071
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0323
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Leishmania major cathepsin L-like protease 0.0071 0.0343 0.1629
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Entamoeba histolytica hypothetical protein 0.0371 0.2071 0.4047
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0242 0.0473
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0133 0.0614
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0734 0.0734
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0528 0.2979 0.2979
Brugia malayi MAP kinase sur-1 0.0055 0.0249 0.0487
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0249 0.1175
Echinococcus granulosus tyrosine protein kinase Lyn 0.09 0.512 0.512
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0047 0.0193
Loa Loa (eye worm) hypothetical protein 0.0144 0.0764 0.1486
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0019 0.0012
Brugia malayi jmjC domain containing protein 0.0039 0.0155 0.0302
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0019 0.017
Brugia malayi tRNA modification GTPase TrmE family protein 0.0528 0.2979 0.5821
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.017 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0031 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Toxoplasma gondii MAPEG family protein 0.1746 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Toxoplasma gondii hypothetical protein 0.0019 0.004 0.0033
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0899 0.5117 0.5117
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.03 0.0587
Schistosoma mansoni cpg binding protein 0.0015 0.002 0.002
Loa Loa (eye worm) 6-phosphofructokinase 0.0055 0.0248 0.0475
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0899 0.5117 0.5117
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0249 0.0249
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0006
Echinococcus multilocularis peregrin 0.0031 0.0112 0.0112
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0018 0.0036 0.0071
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Schistosoma mansoni hypothetical protein 0.0039 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.004 0.0173
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0031 0.0052
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0019 0.004 0.0163
Brugia malayi ephrin receptor 1 precursor 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK/ALK protein kinase 0.0371 0.2071 0.4041
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0021 0.0078
Plasmodium vivax DNA repair protein REV1, putative 0.002 0.0047 0.0194
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0019 0.017
Brugia malayi C-terminal src kinase protein 1 0.0371 0.2071 0.4047
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0019 0.0061
Schistosoma mansoni protein kinase 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0044 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0138 0.027
Onchocerca volvulus 0.0371 0.2071 0.4041
Echinococcus granulosus 6 phosphofructokinase 0.0055 0.0248 0.0248
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0528 0.2979 0.2979
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trypanosoma brucei chrX additional, unordered contigs 0.002 0.0047 0.0193
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.017 0.0323
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0371 0.2071 0.2071
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0054 0.0245 0.8724
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.004 0.004
Echinococcus granulosus expressed protein 0.0036 0.0138 0.0138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Schistosoma mansoni hypothetical protein 0.0206 0.1118 0.1118
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0539 0.2577
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0019 0.007
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.0564 0.0564
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0053 0.0241 0.0462
Leishmania major cytochrome p450-like protein 0.0017 0.0031 0.0119
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus tyrosine protein kinase pr2 0.0371 0.2071 0.2071
Schistosoma mansoni coup transcription factor 0.0041 0.017 0.017
Onchocerca volvulus 0.0528 0.2979 0.5818
Echinococcus granulosus cathepsin l1 0.0019 0.004 0.004
Brugia malayi Doublecortin family protein 0.0013 0.0006 0.0013
Brugia malayi CXXC zinc finger family protein 0.0014 0.0016 0.0031
Trichomonas vaginalis rotamase, putative 0.0036 0.0138 0.0647
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.017 0.017
Trichomonas vaginalis TK family protein kinase 0.0371 0.2071 1
Schistosoma mansoni adapter molecule crk 0.0528 0.2979 0.2979
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0015 0.0015
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0528 0.2979 0.5818
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0016 0.0025 0.069
Loa Loa (eye worm) hypothetical protein 0.0371 0.2071 0.4041
Schistosoma mansoni hypothetical protein 0.0528 0.2979 0.2979
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0019 0.004 0.1629
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.017 0.017
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0019 0.017
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0033
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0019 0.017
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Schistosoma mansoni rab6-interacting 0.0013 0.0006 0.0006
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0258 0.0258
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0133 0.0614
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0371 0.2071 0.4041
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0371 0.2071 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0371 0.2071 0.2071
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0015 0.0018 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0141 0.1844
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0242 0.114
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0067 0.0317 0.0317
Schistosoma mansoni glutaminase 0.0133 0.0702 0.0702
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0249 0.1175
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0139 0.0734 0.352
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0371 0.2071 0.4041
Leishmania major protein kinase, putative 0.0016 0.0024 0.0082
Mycobacterium ulcerans hypothetical protein 0.0051 0.0227 0.3034
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0343 0.1629
Echinococcus granulosus survival motor neuron protein 1 0.0193 0.1043 0.1043
Schistosoma mansoni loxhd1 0.0013 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.017 0.017
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.0564 0.0564
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0899 0.5118 0.5118
Loa Loa (eye worm) glutaminase 0.0133 0.0702 0.1364
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0521 0.0521
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0018 0.0063
Echinococcus granulosus ephrin type A receptor 4 A 0.0371 0.2071 0.2071
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0021 0.0021
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.03 0.03
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus NCK adaptor protein 0.0528 0.2979 0.2979
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0899 0.5117 0.5117
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trichomonas vaginalis CAMK family protein kinase 0.0371 0.2071 1
Loa Loa (eye worm) SH2 domain-containing protein 0.0528 0.2979 0.5818
Schistosoma mansoni tensin-related 0.0528 0.2979 0.2979
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0249 0.0243
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0019 0.017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0027
Echinococcus granulosus tyrosine protein kinase Fyn 0.0899 0.5117 0.5117
Echinococcus granulosus protein tyrosine kinase 0.0371 0.2071 0.2071
Echinococcus granulosus histone lysine methyltransferase setb 0.0015 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.2071 1
Onchocerca volvulus Cathepsin L homolog 0.0019 0.004 0.007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.017 0.017
Schistosoma mansoni growth factor receptor-bound protein 0.0528 0.2979 0.2979
Onchocerca volvulus 0.0015 0.0019 0.0028
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0044 0.0087
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0021 0.0021
Toxoplasma gondii cathepsin CPL 0.0019 0.004 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.004 0.0079
Onchocerca volvulus 0.0019 0.004 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.017 0.0332
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.002 0.0038
Loa Loa (eye worm) RGC/RGC protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis SH2 motif 0.0528 0.2979 0.2979
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0371 0.2071 0.2071
Leishmania major cathepsin L-like protease 0.0019 0.004 0.0163
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0078
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Brugia malayi Pre-SET motif family protein 0.0015 0.0018 0.0036
Echinococcus granulosus tyrosine protein kinase HCK 0.0371 0.2071 0.2071
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Schistosoma mansoni ephrin receptor 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Plasmodium falciparum transporter, putative 0.0019 0.004 0.016
Echinococcus granulosus activated cdc42 kinase 1 0.0371 0.2071 0.2071
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0019 0.0028
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.0457 0.0894
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0047 0.0193
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0044 0.0044
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0019 0.0019
Plasmodium vivax flap endonuclease 1, putative 0.0013 0.0008 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0058 0.0104
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0031 0.0052
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica serine/threonine kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0013 0.0008 0.0006
Brugia malayi Variant SH3 domain containing protein 0.0528 0.2979 0.5821
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.2071 0.4047
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0899 0.5117 0.5117
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Schistosoma mansoni tensin-related 0.0528 0.2979 0.2979
Echinococcus granulosus retinal guanylyl cyclase 2 0.0371 0.2071 0.2071
Brugia malayi Cathepsin L-like precursor 0.0019 0.004 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0371 0.2071 0.2071
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0539 0.732
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Onchocerca volvulus 0.0899 0.5117 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0054 0.0245 0.3278
Entamoeba histolytica tyrosine kinase, putative 0.0371 0.2071 0.4047
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0528 0.2979 0.5818
Loa Loa (eye worm) TK/DDR protein kinase 0.0371 0.2071 0.4041
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0019 0.017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) hypothetical protein 0.0109 0.0564 0.1094
Brugia malayi hypothetical protein 0.0371 0.2071 0.4047
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Echinococcus granulosus dna polymerase eta 0.0091 0.0457 0.0457
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Brugia malayi SH2 domain containing protein 0.0528 0.2979 0.5821
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0528 0.2979 0.5818
Onchocerca volvulus 0.0116 0.0601 0.1167
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0227 0.3034
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0102 0.052 0.1008
Onchocerca volvulus 0.0019 0.004 0.007
Echinococcus granulosus SH2 domain containing protein 7 0.0528 0.2979 0.2979
Echinococcus multilocularis activated cdc42 kinase 1 0.0371 0.2071 0.2071
Plasmodium vivax vivapain-2 0.0019 0.004 0.0163
Echinococcus granulosus tyrosine protein kinase csk 0.0371 0.2071 0.2071
Loa Loa (eye worm) DR-78 0.0019 0.0044 0.0078
Onchocerca volvulus 0.0041 0.017 0.0323
Brugia malayi Protein kinase domain containing protein 0.0899 0.5117 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0044 0.0044
Entamoeba histolytica ankyrin repeat protein 0.0371 0.2071 0.4047
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.017 0.0323
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0371 0.2071 0.2071
Echinococcus granulosus single minded 2 0.0044 0.0184 0.0184
Plasmodium falciparum glutathione reductase 0.0024 0.0069 0.0305
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.004 0.0462
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0031 0.0119
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0019 0.006
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.017 0.0332
Echinococcus granulosus tyrosine protein kinase Src64B 0.0899 0.5117 0.5117
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.017 0.0323
Entamoeba histolytica protein kinase, putative 0.0529 0.2982 0.5827
Mycobacterium ulcerans glutaminase 0.0133 0.0702 0.9558
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0899 0.5117 0.5117
Onchocerca volvulus 0.0014 0.0016 0.0022
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0371 0.2071 0.2071
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0371 0.2071 0.2071
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0249 0.1185
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0019 0.004 0.0079
Echinococcus multilocularis 0.0528 0.2979 0.2979
Echinococcus multilocularis microsomal glutathione S transferase 3 0.1746 1 1
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Onchocerca volvulus 0.0015 0.0019 0.0028
Brugia malayi glutaminase DH11.1 0.0133 0.0702 0.1372
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0242 0.0473
Trypanosoma brucei protein kinase, putative 0.0055 0.0249 0.1175
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.004 0.0173
Brugia malayi hypothetical protein 0.0022 0.0058 0.0113
Brugia malayi Protein kinase domain containing protein 0.0371 0.2071 0.4047
Plasmodium falciparum tyrosine kinase-like protein 0.0371 0.2071 0.9986
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0227 0.8074
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0131
Echinococcus multilocularis SH2 domain containing protein 7 0.0528 0.2979 0.2979
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.004 0.004
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0371 0.2071 0.2071
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.004 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0343 0.1629
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0074 0.036 0.4852
Schistosoma mansoni protein kinase 0.0371 0.2074 0.2074
Entamoeba histolytica protein kinase, putative 0.0371 0.2071 0.4047
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.2074 1
Trypanosoma brucei protein kinase, putative 0.0371 0.2074 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0054 0.0245 0.3278
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0019 0.017
Echinococcus granulosus RUN 0.0013 0.0006 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.0139 0.0734 0.0728
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0227 0.3034
Echinococcus granulosus raf serine:threonine protein kinase 0.0371 0.2071 0.2071
Loa Loa (eye worm) TK/FER protein kinase 0.0371 0.2071 0.4041
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0006 0.0006
Brugia malayi hypothetical protein 0.0013 0.0006 0.0013
Schistosoma mansoni tyrosine kinase 0.0899 0.5117 0.5117
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.017 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0019 0.017
Brugia malayi hypothetical protein 0.0528 0.2979 0.5821
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.017 0.017
Echinococcus multilocularis tyrosine protein kinase csk 0.0371 0.2071 0.2071
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.029
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0055 0.0248 0.1166
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0058 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0245 0.1155
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0068
Schistosoma mansoni tensin 0.0528 0.2979 0.2979
Echinococcus granulosus nuclear factor of activated T cells 5 0.004 0.0165 0.0165
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0017 0.0033 0.0055
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.017 0.0323
Entamoeba histolytica tyrosin kinase, putative 0.0371 0.2071 0.4047
Echinococcus multilocularis epidermal growth factor receptor 0.0371 0.2071 0.2071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.017 0.017
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.0371 0.2071 0.2071
Schistosoma mansoni jumonji domain containing protein 0.0081 0.04 0.04
Loa Loa (eye worm) TK protein kinase 0.0371 0.2071 0.4041
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0019 0.006
Trichomonas vaginalis TKL family protein kinase 0.0371 0.2071 1
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0019 0.017
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.5117 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0371 0.2071 0.4047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0054 0.0245 0.3278

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 875.9 nM Inhibition of [3H]-WIN- 35,428 binding to Dopamine transporter in rat striatal synaptic membranes ChEMBL. 11714614
IC50 (binding) = 875.9 nM Inhibition of [3H]-WIN- 35,428 binding to Dopamine transporter in rat striatal synaptic membranes ChEMBL. 11714614

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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