Detailed information for compound 233835

Basic information

Technical information
  • TDR Targets ID: 233835
  • Name: (2S)-6-[[(2S)-2-amino-3-phenylpropanoyl]amino ]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl )amino]hexanoic acid
  • MW: 503.654 | Formula: C26H37N3O5S
  • H donors: 3 H acceptors: 5 LogP: 1.58 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(CN(S(=O)(=O)c1ccc(cc1)C)[C@H](C(=O)O)CCCCNC(=O)[C@H](Cc1ccccc1)N)C
  • InChi: 1S/C26H37N3O5S/c1-19(2)18-29(35(33,34)22-14-12-20(3)13-15-22)24(26(31)32)11-7-8-16-28-25(30)23(27)17-21-9-5-4-6-10-21/h4-6,9-10,12-15,19,23-24H,7-8,11,16-18,27H2,1-3H3,(H,28,30)(H,31,32)/t23-,24-/m0/s1
  • InChiKey: DCNBOHVQLTUPPO-ZEQRLZLVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-6-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-2-[isobutyl(p-tolylsulfonyl)amino]hexanoic acid
  • (2S)-6-[[(2S)-2-amino-1-oxo-3-phenylpropyl]amino]-2-[isobutyl(p-tolylsulfonyl)amino]hexanoic acid
  • (2S)-6-[[(2S)-2-azanyl-3-phenyl-propanoyl]amino]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl)amino]hexanoic acid
  • (2S)-6-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-2-[isobutyl(tosyl)amino]hexanoic acid
  • (2S)-6-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-2-[isobutyl-(4-methylphenyl)sulfonyl-amino]hexanoic acid
  • (2S)-6-[[(2S)-2-amino-1-oxo-3-phenylpropyl]amino]-2-[isobutyl-(4-methylphenyl)sulfonylamino]hexanoic acid
  • (2S)-6-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl)amino]hexanoic acid
  • AIDS-180145
  • AIDS180145
  • N.alpha.-isobutyl-N.alpha.-(4-methylbenzenesulfonyl)-N.epsilon.-(L-phenylalanyl)-L-lysine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0002 0.0006
Echinococcus granulosus lipoxygenase domain containing protein 0.0119 0.0474 0.0474
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0086 0.0209
Loa Loa (eye worm) TK/EPH protein kinase 0.0172 0.0732 0.1533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Schistosoma mansoni serine/threonine RGC 0.0029 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0176 0.1274
Entamoeba histolytica protein kinase, putative 0.0078 0.0279 0.1905
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0027 0.0031 0.0225
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0082 0.0297 0.0621
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0697 0.0697
Giardia lamblia Kinase, AGC PKA 0.0052 0.0155 0.0975
Loa Loa (eye worm) hypothetical protein 0.0082 0.0297 0.0621
Leishmania major protein kinase, putative 0.0023 0.0011 0.0055
Echinococcus granulosus cyclins 0.0037 0.0078 0.0078
Echinococcus granulosus tyrosine protein kinase ABL1 0.0044 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0159 0.0669 0.14
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0302 0.1358 0.1358
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0044 0.0044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0465 0.0671
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0025 0.0172
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Echinococcus granulosus tyrosine protein kinase otk 0.0036 0.0077 0.0077
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0122 0.0492 0.0492
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0086 0.0086
Trypanosoma cruzi cyclin, putative 0.0037 0.0078 0.0553
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0042 0.0134
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0188 0.1367
Echinococcus granulosus hemicentin 1 0.0036 0.0077 0.0077
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.017 0.017
Leishmania major DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0649 0.097
Mycobacterium ulcerans hypothetical protein 0.0031 0.0053 0.0073
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0241 0.1061 0.1061
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Leishmania major protein kinase, putative 0.0029 0.0042 0.0288
Echinococcus granulosus tyrosine kinase 0.0104 0.0405 0.0405
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica cell division protein kinase 2, putative 0.0098 0.0375 0.2625
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0029 0.0029
Echinococcus multilocularis Mastin 0.0031 0.0053 0.0053
Giardia lamblia Hypothetical protein 0.0037 0.0078 0.0403
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0086 0.0086
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0042 0.0102
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Schistosoma mansoni DNA polymerase eta 0.0062 0.0203 0.0203
Schistosoma mansoni nuclear receptor 0.0026 0.0029 0.0029
Giardia lamblia Cyclin A 0.0037 0.0078 0.0403
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0065
Plasmodium vivax multidomain scavenger receptor, putative 0.0119 0.0474 0.3696
Brugia malayi hypothetical protein 0.0119 0.0474 0.1144
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0083 0.0442
Giardia lamblia Kinase, CMGC CK2 0.0278 0.1241 0.9121
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0029 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0031 0.0053 0.0053
Loa Loa (eye worm) TK/DDR protein kinase 0.0029 0.0042 0.0089
Echinococcus multilocularis 0.0261 0.1157 0.1157
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trypanosoma cruzi polo-like protein kinase, putative 0.0302 0.1358 1
Giardia lamblia Kinase, NEK 0.0029 0.0042 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0056 0.017 0.0357
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0074 0.0074
Echinococcus granulosus expressed protein 0.0745 0.3489 0.3489
Brugia malayi Trypsin family protein 0.0031 0.0053 0.0128
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0029 0.0042 0.0042
Brugia malayi Doublecortin family protein 0.0119 0.0474 0.1144
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Loa Loa (eye worm) hypothetical protein 0.0297 0.1333 0.2792
Entamoeba histolytica cell division protein kinase 2, putative 0.0098 0.0375 0.2625
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Onchocerca volvulus 0.0031 0.0051 0.0071
Toxoplasma gondii hypothetical protein 0.0048 0.0131 0.1032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0056 0.017 0.017
Echinococcus multilocularis nervana 2 0.0042 0.0105 0.0105
Brugia malayi ecdysone receptor 0.0026 0.0029 0.0069
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Mycobacterium tuberculosis Probable oxidoreductase 0.0031 0.0051 0.0072
Echinococcus multilocularis microtubule associated protein 2 0.2098 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Schistosoma mansoni tyrosine kinase 0.0881 0.4143 0.4143
Echinococcus granulosus Mastin 0.0031 0.0053 0.0053
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0083 0.0116
Plasmodium falciparum serine/threonine protein kinase, putative 0.0241 0.1061 0.8522
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0188 0.1367
Trypanosoma cruzi cyclin, putative 0.0037 0.0078 0.0553
Echinococcus granulosus fibroblast growth factor receptor 4 0.0029 0.0042 0.0042
Brugia malayi Csnk2b protein 0.0036 0.0074 0.0179
Onchocerca volvulus 0.0031 0.0051 0.0071
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0086 0.0386
Echinococcus multilocularis cyclin dependent kinase 0.0098 0.0375 0.0375
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0165 0.0697 0.1683
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0031 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Brugia malayi Protein kinase domain containing protein 0.0078 0.0279 0.0672
Onchocerca volvulus 0.0028 0.0035 0.0019
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Toxoplasma gondii CMGC kinase, CK2 family 0.0278 0.1241 1
Entamoeba histolytica protein kinase domain containing protein 0.0278 0.1241 0.9121
Echinococcus multilocularis ephrin type A receptor 4 A 0.0168 0.0712 0.0712
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.017 0.017
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0074 0.0574
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0077 0.016
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0042 0.0134
Onchocerca volvulus 0.0099 0.0378 0.1102
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0409 0.0609
Echinococcus granulosus Glutaredoxin protein 5 0.0042 0.0105 0.0105
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0056 0.017 0.0411
Echinococcus multilocularis roundabout 2 0.0048 0.0133 0.0133
Brugia malayi conserved hypotetical protein 0.0026 0.0029 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0202 0.1466
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) TK/Met protein kinase 0.0029 0.0042 0.0089
Entamoeba histolytica protein kinase, putative 0.0089 0.0331 0.2302
Mycobacterium ulcerans oxidoreductase 0.0031 0.0051 0.0069
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0165 0.0697 0.0697
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0044 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.0782 0.575
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Trypanosoma brucei rac serine-threonine kinase, putative 0.0078 0.0279 0.2032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0056 0.017 0.0411
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0083 0.0083
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0051 0.0223
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0119 0.0287
Echinococcus multilocularis tyrosine kinase 0.0029 0.0042 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0083 0.0592
Echinococcus multilocularis tumor protein p63 0.033 0.1489 0.1489
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0133 0.032
Echinococcus multilocularis tyrosine protein kinase shark 0.0044 0.0116 0.0116
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0048 0.0135 0.0284
Leishmania major hypothetical protein, conserved 0.0029 0.0042 0.0288
Echinococcus multilocularis tyrosine protein kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0036 0.0077 0.0077
Brugia malayi nuclear receptor RXR 0.0029 0.0044 0.0106
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0086 0.0086
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0048 0.0133 0.0812
Schistosoma mansoni adapter molecule crk 0.003 0.0047 0.0047
Schistosoma mansoni Neurotrimin precursor (hNT) 0.007 0.0241 0.0241
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Brugia malayi serine/threonine kinase 12 0.0241 0.1061 0.256
Entamoeba histolytica cyclin family protein 0.0037 0.0078 0.0403
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Schistosoma mansoni tyrosine kinase 0.0547 0.2538 0.2538
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0042 0.0102
Brugia malayi Cytochrome P450 family protein 0.0038 0.0087 0.021
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0029 0.0042 0.0042
Trichomonas vaginalis cyclin B, putative 0.0037 0.0078 0.0348
Onchocerca volvulus 0.0029 0.0042 0.0043
Schistosoma mansoni cell adhesion molecule 0.0048 0.0133 0.0133
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0409 0.0609
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0056 0.017 0.017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0057 0.0175 0.1128
Schistosoma mansoni hypothetical protein 0.0165 0.0698 0.0698
Echinococcus multilocularis plexin a4 0.0042 0.0105 0.0105
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0086 0.0086
Brugia malayi tailless protein 0.0026 0.0029 0.0069
Brugia malayi Casein kinase II, alpha chain 0.0278 0.1241 0.2994
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0769 0.3602 0.3602
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Echinococcus granulosus protein tyrosine kinase 0.0547 0.2538 0.2538
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0035 0.0035
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0056 0.017 0.017
Schistosoma mansoni cyclin B3 0.0037 0.0078 0.0078
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0029 0.0042 0.0042
Loa Loa (eye worm) oxidoreductase 0.0031 0.0051 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Toxoplasma gondii thioredoxin reductase 0.0046 0.0124 0.0978
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0154
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0609 0.1276
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0087 0.0183
Echinococcus multilocularis 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Schistosoma mansoni microtubule-associated protein tau 0.2098 1 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0029 0.0029
Schistosoma mansoni coup transcription factor 0.0056 0.017 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0119 0.0474 0.0993
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Schistosoma mansoni protein kinase 0.0197 0.0851 0.0851
Echinococcus granulosus enteropeptidase 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0432 0.1982 0.4152
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0029 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0188 0.0854
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0083 0.0175
Plasmodium vivax glutathione reductase, putative 0.0046 0.0124 0.082
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0031 0.0051 0.0352
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Schistosoma mansoni plexin 0.0036 0.0074 0.0074
Echinococcus multilocularis aldo keto reductase 0.0031 0.0051 0.0051
Echinococcus granulosus cyclin b3 0.0037 0.0078 0.0078
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0086 0.0086
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0056 0.017 0.0447
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0083 0.0121
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) steroid hormone receptor 0.0056 0.017 0.0357
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0025 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Plasmodium falciparum conserved protein, unknown function 0.0027 0.0031 0.0054
Echinococcus granulosus Polycystic kidney disease protein 0.0119 0.0474 0.0474
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0324 0.0324
Giardia lamblia DINP protein human, muc B family 0.0038 0.0083 0.0442
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0027 0.0031 0.0054
Onchocerca volvulus 0.0035 0.0071 0.0135
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0188 0.0854
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0191 0.0273
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0087 0.0122
Brugia malayi Fibronectin type III domain containing protein 0.0082 0.0297 0.0716
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0051 0.0223
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica hypothetical protein 0.0035 0.0071 0.035
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0032 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0112 0.0443 0.0929
Schistosoma mansoni tyrosine kinase 0.0568 0.2635 0.2635
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Trypanosoma brucei aldo-keto reductase, putative 0.0031 0.0051 0.0352
Trichomonas vaginalis cyclin B, putative 0.0037 0.0078 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0056 0.017 0.0411
Brugia malayi Cyclin, N-terminal domain containing protein 0.0037 0.0078 0.0189
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0191 0.1386
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0165 0.0697 0.211
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Trypanosoma cruzi protein kinase, putative 0.0029 0.0042 0.0288
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0048 0.0135 0.0284
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0071 0.0071
Echinococcus multilocularis transmembrane protease serine 3 0.0031 0.0053 0.0053
Brugia malayi steroid hormone receptor 0.0056 0.017 0.0411
Echinococcus multilocularis muscleblind protein 0.0297 0.1333 0.1333
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0025 0.0157
Schistosoma mansoni tyrosine kinase 0.0568 0.2635 0.2635
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0188 0.1367
Schistosoma mansoni tyrosine kinase 0.0119 0.0477 0.0477
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0165 0.0697 0.0697
Brugia malayi hypoxia-induced factor 1 0.0147 0.0609 0.147
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0059 0.0187 0.0187
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0051 0.0223
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0102 0.0726
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0048 0.0133 0.0957
Plasmodium falciparum LCCL domain-containing protein 0.0119 0.0474 0.3696
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0031 0.0054
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Brugia malayi Peroxidasin 0.0036 0.0077 0.0185
Leishmania major aldo-keto reductase-like protein 0.0031 0.0051 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0029 0.0029
Echinococcus granulosus aldo keto reductase 0.0031 0.0051 0.0051
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0083 0.0121
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0409 0.0609
Schistosoma mansoni zinc finger protein 0.0026 0.0029 0.0029
Echinococcus multilocularis serine threonine protein kinase 0.0032 0.0055 0.0055
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni pol-related 0.0031 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0029 0.0042 0.0134
Schistosoma mansoni cyclin B 0.0037 0.0078 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis aurora kinase A 0.0241 0.1061 0.1061
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0114 0.0114
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0071 0.0071
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0074 0.0144
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0051 0.0123
Trypanosoma cruzi cdc2-related kinase 1 0.0098 0.0375 0.2741
Toxoplasma gondii aldose reductase, putative 0.0031 0.0051 0.0386
Plasmodium falciparum cysteine repeat modular protein 1 0.0027 0.0031 0.0054
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0119 0.0477 0.0477
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0087 0.0183
Loa Loa (eye worm) hypothetical protein 0.007 0.0241 0.0504
Schistosoma mansoni serine/threonine-protein kinase 0.0057 0.0175 0.0175
Onchocerca volvulus 0.0099 0.0378 0.1102
Echinococcus multilocularis Protein lozenge 0.0054 0.0163 0.0163
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0029 0.0069
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Entamoeba histolytica cyclin, putative 0.0037 0.0078 0.0403
Brugia malayi hypothetical protein 0.0035 0.0071 0.0172
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni cell adhesion molecule 0.0048 0.0133 0.0133
Trypanosoma brucei Pseudokinase, putative 0.0029 0.0042 0.0288
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0098 0.0375 0.2741
Giardia lamblia CEGP1 protein 0.0027 0.0031 0.005
Echinococcus multilocularis casein kinase ii subunit alpha 0.0278 0.1241 0.1241
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0042 0.0146
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0029 0.0042 0.0042
Trypanosoma brucei aurora B kinase 0.0241 0.1061 0.7808
Onchocerca volvulus 0.0031 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0029 0.0042 0.0089
Echinococcus granulosus aldehyde reductase 0.0022 0.0008 0.0008
Schistosoma mansoni tyrosine kinase 0.0568 0.2635 0.2635
Echinococcus multilocularis musashi 0.0026 0.0029 0.0029
Trypanosoma cruzi CYC2-like cyclin, putative 0.0037 0.0078 0.0553
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0042 0.0042
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0042 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0082 0.0082
Toxoplasma gondii ck2 beta subunit 0.0036 0.0074 0.0574
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0302 0.1358 0.1358
Echinococcus multilocularis lamin 0.0026 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0241 0.1061 0.4864
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0052 0.0155 0.0155
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0029 0.0029
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.132 0.9724
Echinococcus multilocularis epidermal growth factor receptor 0.0597 0.2775 0.2775
Brugia malayi ephrin receptor 1 precursor 0.0082 0.0297 0.0718
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0056 0.017 0.017
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.0011 0.0055
Echinococcus granulosus protein kinase c epsilon type 0.0032 0.0055 0.0055
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0039 0.0091 0.0712
Trichomonas vaginalis AGC family protein kinase 0.0036 0.0075 0.0335
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0056 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Onchocerca volvulus 0.0031 0.0053 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0029 0.0029
Brugia malayi Sex muscle abnormal protein 5 0.003 0.0047 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0191 0.0282
Onchocerca volvulus 0.0026 0.0029 0.0001
Echinococcus multilocularis RUN 0.0119 0.0474 0.0474
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0302 0.1358 0.2844
Entamoeba histolytica serine/threonine protein kinase, putative 0.0302 0.1358 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0083 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0033 0.0062 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0031 0.0053 0.0053
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0212 0.1543
Onchocerca volvulus 0.0119 0.0474 0.1405
Brugia malayi hypothetical protein 0.0044 0.0116 0.028
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0056 0.017 0.017
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0188 0.0188
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0059 0.0187 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0029 0.0069
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0083 0.0592
Brugia malayi hypothetical protein 0.0026 0.0029 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0056 0.017 0.0411
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0102 0.0726
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.017 0.0411
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Echinococcus granulosus dna polymerase kappa 0.0038 0.0083 0.0083
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Onchocerca volvulus 0.0029 0.0042 0.0043
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0029 0.0042 0.0183
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0086 0.0086
Echinococcus multilocularis NCK adaptor protein 0.003 0.0047 0.0047
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.0051 0.0352
Echinococcus multilocularis ecdysone induced protein 78C 0.0056 0.017 0.017
Echinococcus granulosus tyrosine protein kinase Srms 0.0044 0.0116 0.0116
Onchocerca volvulus 0.0038 0.0084 0.0174
Brugia malayi nuclear receptor RXR 0.0026 0.0029 0.0069
Loa Loa (eye worm) DR-78 0.0026 0.0029 0.006
Loa Loa (eye worm) protein kinase domain-containing protein 0.0029 0.0042 0.0089
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0048 0.0133 0.0133
Trichomonas vaginalis cyclin B, putative 0.0037 0.0078 0.0348
Leishmania major DNA polymerase eta, putative 0.0037 0.0078 0.0553
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0048 0.0133 0.0133
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0131 0.0131
Onchocerca volvulus 0.0029 0.0042 0.0043
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0032 0.0055 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0055 0.0241
Schistosoma mansoni loxhd1 0.0119 0.0474 0.0474
Brugia malayi Plexin repeat family protein 0.0036 0.0074 0.0177
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0048 0.0133 0.0133
Onchocerca volvulus 0.0027 0.0031 0.0008
Schistosoma mansoni nephrin 0.0048 0.0133 0.0133
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus multilocularis epidermal growth factor receptor 0.0881 0.4143 0.4143
Brugia malayi Pre-SET motif family protein 0.006 0.0189 0.0456
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0073
Echinococcus multilocularis tyrosine protein kinase otk 0.0036 0.0077 0.0077
Trypanosoma brucei Flagellum attachment zone protein 20 0.0029 0.0042 0.0288
Schistosoma mansoni intermediate filament proteins 0.0026 0.0029 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0056 0.017 0.017
Loa Loa (eye worm) TK/INSR protein kinase 0.0757 0.3546 0.7429
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Onchocerca volvulus 0.0044 0.0116 0.0275
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0083 0.0202
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni cell adhesion molecule 0.0028 0.0035 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Schistosoma mansoni vesicular amine transporter 0.007 0.0241 0.0241
Echinococcus multilocularis FTZ F1 alpha 0.0056 0.017 0.017
Echinococcus granulosus lamin 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0032 0.0056 0.0056
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0042 0.0042
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0074 0.0524
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0029 0.0029
Trypanosoma brucei protein kinase, putative 0.0039 0.0091 0.0651
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0065
Loa Loa (eye worm) hypothetical protein 0.0044 0.0116 0.0243
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus cyclins 0.0037 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Trypanosoma brucei unspecified product 0.0026 0.0027 0.0177
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0189 0.1502
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0119 0.0249
Echinococcus granulosus protein kinase C gamma type 0.0032 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.0464
Echinococcus granulosus tyrosine protein kinase Src42A 0.0119 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0025 0.0157
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0042 0.0042
Brugia malayi serine/threonine-protein kinase 6 0.0241 0.1061 0.256
Onchocerca volvulus 0.0029 0.0042 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0375 0.171
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0375 0.0375
Trypanosoma brucei protein kinase, putative 0.0059 0.0188 0.1367
Loa Loa (eye worm) runx1 0.0054 0.0163 0.0342
Schistosoma mansoni hypothetical protein 0.0165 0.0698 0.0698
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0465 0.0694
Schistosoma mansoni tyrosine kinase 0.0597 0.2775 0.2775
Echinococcus granulosus hypothetical protein 0.0031 0.0051 0.0051
Schistosoma mansoni polycystin 1-related 0.0119 0.0474 0.0474
Leishmania major prostaglandin f synthase, putative 0.0031 0.0051 0.0352
Trypanosoma brucei trypanothione reductase 0.0046 0.0124 0.0893
Loa Loa (eye worm) hypothetical protein 0.007 0.0241 0.0504
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0071 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0202 0.1466
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Entamoeba histolytica protein kinase , putative 0.0241 0.1061 0.7773
Schistosoma mansoni cytochrome P450 0.0021 0.0003 0.0003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0573 0.4209
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0573 0.4209
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0042 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Schistosoma mansoni hypothetical protein 0.0119 0.0474 0.0474
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0191 0.0273
Loa Loa (eye worm) oxidoreductase 0.0031 0.0051 0.0107
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0032 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0278 0.1241 0.2599
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0031 0.0053 0.0128
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0025 0.0157
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Schistosoma mansoni cell adhesion molecule 0.0102 0.0394 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni hypothetical protein 0.0028 0.0035 0.0035
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0029 0.006
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0055 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.132 0.9724
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis aldo keto reductase 0.0031 0.0051 0.0051
Schistosoma mansoni hemicentin 0.0028 0.0035 0.0035
Leishmania major cytochrome p450-like protein 0.0038 0.0087 0.0619
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0048 0.0133 0.1047
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0138 0.0992
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0078 0.0348
Brugia malayi SH2 domain containing protein 0.0044 0.0116 0.028
Plasmodium falciparum glutathione reductase 0.0046 0.0124 0.082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Trypanosoma brucei unspecified product 0.0038 0.0083 0.0592
Echinococcus granulosus tyrosine protein kinase shark 0.0044 0.0116 0.0116
Schistosoma mansoni lipoxygenase 0.037 0.1683 0.1683
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0091 0.0651
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Brugia malayi protein kinase C II. 0.0032 0.0055 0.0133
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0025 0.0051
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0098 0.0375 0.0784
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Echinococcus multilocularis Immunoglobulin 0.007 0.0241 0.0241
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0324 0.0324
Echinococcus granulosus defective proboscis extension response 0.007 0.0241 0.0241
Giardia lamblia Kinase 0.0029 0.0042 0.0134
Echinococcus granulosus twitchin 0.0096 0.0366 0.0366
Brugia malayi nuclear hormone receptor 0.0026 0.0029 0.0069
Echinococcus granulosus cyclins 0.0037 0.0078 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0432 0.1982 0.4152
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Entamoeba histolytica aldose reductase, putative 0.0031 0.0051 0.0199
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0036 0.0077 0.0077
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0203 0.1475
Schistosoma mansoni neuroglian 0.0048 0.0133 0.0133
Brugia malayi Trypsin-like protease protein 5 0.0031 0.0053 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0056 0.017 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Echinococcus granulosus tyrosine kinase 0.0044 0.0116 0.0116
Onchocerca volvulus 0.0029 0.0042 0.0043
Echinococcus granulosus serine/threonine protein kinase 0.0057 0.0175 0.0175
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0042 0.0042
Trypanosoma brucei cdc2-related kinase 3 0.0098 0.0375 0.2741
Brugia malayi hypothetical protein 0.0029 0.0042 0.0102
Trypanosoma brucei cdc2-related kinase 1 0.0098 0.0375 0.2741
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Echinococcus granulosus protein kinase 0.0029 0.0042 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0782 0.1131
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Schistosoma mansoni plexin 0.0021 0.0002 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0029 0.0042 0.0089
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus granulosus Immunoglobulin 0.007 0.0241 0.0241
Giardia lamblia Hypothetical protein 0.0027 0.0031 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Loa Loa (eye worm) TK/ALK protein kinase 0.0029 0.0042 0.0089
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Loa Loa (eye worm) hypothetical protein 0.0119 0.0474 0.0993
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Echinococcus granulosus cyclin dependent kinase 0.0098 0.0375 0.0375
Schistosoma mansoni hypothetical protein 0.0021 0.0002 0.0002
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0241 0.1061 0.7773
Schistosoma mansoni serine/threonine kinase 0.0032 0.0055 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0056 0.017 0.0357
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Echinococcus multilocularis protein tyrosine kinase 0.0547 0.2538 0.2538
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Echinococcus granulosus endonuclease reverse transcriptase 0.0027 0.0031 0.0031
Echinococcus multilocularis cyclin b3 0.0037 0.0078 0.0078
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0029 0.0042 0.0089
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0029 0.0042 0.0134
Entamoeba histolytica aldose reductase, putative 0.0031 0.0051 0.0199
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0056 0.017 0.017
Echinococcus granulosus cyclin dependent kinase 5 0.0098 0.0375 0.0375
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0092
Echinococcus granulosus nephrin 0.0028 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase Srms 0.0104 0.0405 0.0405
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0083 0.0592
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0212 0.1543
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0074 0.0144
Schistosoma mansoni tyrosine kinase 0.0044 0.0116 0.0116
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0124 0.0893
Loa Loa (eye worm) trypsin family protein 0.0031 0.0053 0.0112
Brugia malayi hypothetical protein 0.0432 0.1982 0.4784
Echinococcus granulosus aldo keto reductase 0.0031 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0092
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0048 0.0133 0.0195
Echinococcus multilocularis tyrosine protein kinase Abl 0.0059 0.0187 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0188 0.0188
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Loa Loa (eye worm) TK/ACK protein kinase 0.0029 0.0042 0.0089
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0029 0.0042 0.0042
Echinococcus multilocularis hemicentin 1 0.0036 0.0077 0.0077
Entamoeba histolytica cyclin, putative 0.0037 0.0078 0.0403
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Echinococcus multilocularis protein kinase c epsilon type 0.0032 0.0055 0.0055
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0133 0.0278
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0055 0.0055
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0029 0.0042 0.0134
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Onchocerca volvulus 0.0031 0.0053 0.0078
Echinococcus granulosus tyrosine kinase 0.0029 0.0042 0.0042
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0048 0.0133 0.0188
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0119 0.0477 0.0477
Schistosoma mansoni nuclear receptor 0.0026 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Schistosoma mansoni titin 0.0038 0.0084 0.0084
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0098 0.0375 0.0784
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1451 0.689 1
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0029 0.006
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Trichomonas vaginalis set domain proteins, putative 0.0473 0.2178 1
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Giardia lamblia Casein kinase II beta chain 0.0036 0.0074 0.0373
Echinococcus multilocularis nervana 2 0.0042 0.0105 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Loa Loa (eye worm) hypothetical protein 0.0091 0.0338 0.0709
Onchocerca volvulus 0.0031 0.0053 0.0078
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0086 0.0086
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0022 0.0006 0.0016
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0042 0.0089
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0052 0.0155 0.1069
Brugia malayi protein unc-22 0.0038 0.0084 0.0202
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0136 0.0286
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0031 0.005
Leishmania major protein kinase, putative 0.0023 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Loa Loa (eye worm) hypothetical protein 0.003 0.0047 0.0099
Brugia malayi nuclear receptor NHR-67 0.0026 0.0029 0.0069
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0042 0.0043
Echinococcus multilocularis lamin dm0 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0084 0.0084
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0042 0.0089
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0188 0.1367
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0056 0.017 0.0357
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0241 0.1061 0.8522
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni protein kinase 0.0278 0.1241 0.1241
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0029 0.0042 0.0089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0189 0.0189
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0086 0.0086
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0029 0.0042 0.0102
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0409 0.0609
Echinococcus multilocularis titin 0.0038 0.0084 0.0084
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0409 0.0589
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0044 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.017 0.0411
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0188 0.1367
Schistosoma mansoni protein kinase 0.0039 0.0091 0.0091
Mycobacterium tuberculosis Probable reductase 0.0105 0.0409 0.0609
Brugia malayi hypothetical protein 0.0119 0.0474 0.1144
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0088 0.0325 0.0682
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Brugia malayi bone morphogenetic protein type 1 receptor 0.0029 0.0042 0.0102
Toxoplasma gondii aurora kinase 0.0241 0.1061 0.8547
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0189 0.0189
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0375 0.171
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0031 0.0075
Brugia malayi hypothetical protein 0.0029 0.0042 0.0102
Echinococcus multilocularis protein kinase c iota type 0.0032 0.0055 0.0055
Onchocerca volvulus 0.064 0.2981 0.9316
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0042 0.0102
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0098 0.0375 0.3
Schistosoma mansoni cell adhesion molecule 0.0028 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Brugia malayi Trypsin family protein 0.0031 0.0053 0.0128
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0044 0.0044
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0032 0.0055 0.0055
Echinococcus granulosus nervana 2 0.0042 0.0105 0.0105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.017 0.0411
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus granulosus roundabout 2 0.0048 0.0133 0.0133
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0074 0.0409
Brugia malayi SRC-1 0.0119 0.0477 0.115
Loa Loa (eye worm) hypothetical protein 0.0082 0.0297 0.0621
Echinococcus multilocularis roundabout 2 0.0048 0.0133 0.0133
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0031 0.0051 0.0069
Echinococcus multilocularis cyclin B3 1 0.0037 0.0078 0.0078
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0029 0.0029
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0042 0.0134
Schistosoma mansoni atypical protein kinase C 0.0032 0.0055 0.0055
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0124 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Echinococcus granulosus beta-adrenergic receptor kinase 0.0048 0.0135 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Plasmodium vivax protein kinase Crk2 0.0098 0.0375 0.2878
Loa Loa (eye worm) TK/RYK protein kinase 0.0029 0.0042 0.0089
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0056 0.017 0.017
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0119 0.0477 0.0477
Brugia malayi cell division control protein 2 homolog 0.0098 0.0375 0.0904
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0058 0.0182 0.038
Entamoeba histolytica hypothetical protein 0.0027 0.0031 0.005
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.0464
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.017 0.017
Echinococcus multilocularis kinase suppressor of Ras 1 0.0029 0.0042 0.0042
Brugia malayi ecdysteroid receptor 0.0056 0.017 0.0411
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0029 0.006
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Onchocerca volvulus 0.0036 0.0074 0.0142
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0102 0.0726
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0465 0.0694
Schistosoma mansoni nephrin 0.0098 0.0373 0.0373
Schistosoma mansoni rab6-interacting 0.0119 0.0474 0.0474
Plasmodium vivax protein kinase, putative 0.0038 0.0085 0.0496
Brugia malayi Variant SH3 domain containing protein 0.003 0.0047 0.0114
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Echinococcus multilocularis heat shock protein 70 0.0029 0.0042 0.0042
Echinococcus granulosus protein kinase c iota type 0.0032 0.0055 0.0055
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Brugia malayi Protein kinase domain containing protein 0.0757 0.3546 0.856
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus granulosus muscleblind protein 0.0297 0.1333 0.1333
Toxoplasma gondii kringle domain-containing protein 0.0027 0.0031 0.0225
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0056 0.017 0.0357
Entamoeba histolytica hypothetical protein 0.0035 0.0071 0.035
Schistosoma mansoni aldo-keto reductase 0.0031 0.0051 0.0051
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Trypanosoma cruzi cyclin 6, putative 0.0037 0.0078 0.0553
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0087 0.0183
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni cyclins 0.0037 0.0078 0.0078
Echinococcus multilocularis protein kinase 0.0029 0.0042 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0084 0.0202
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0188 0.1367
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0074 0.0373
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0042 0.0042
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0074 0.0409
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Onchocerca volvulus 0.0029 0.0042 0.0043
Onchocerca volvulus 0.0119 0.0474 0.1405
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.007 0.0241 0.0504
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0086 0.0181
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0597 0.2775 0.2775
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trypanosoma cruzi casein kinase II, putative 0.0278 0.1241 0.9135
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0035 0.0073
Onchocerca volvulus Tyrosine kinase homolog 0.0685 0.3198 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0188 0.1367
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Onchocerca volvulus 0.0027 0.0031 0.0008
Echinococcus granulosus c src tyrosine kinase 0.0059 0.0187 0.0187
Giardia lamblia G2/mitotic-specific cyclin B 0.0037 0.0078 0.0403
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0189 0.0189
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0077 0.016
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0029 0.0069
Onchocerca volvulus 0.0048 0.0134 0.0334
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0078 0.0605
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0023 0.0011 0.0055
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1404 0.6659 1
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1451 0.689 1
Echinococcus multilocularis natriuretic peptide receptor 1 0.0029 0.0042 0.0042
Brugia malayi hypothetical protein 0.0029 0.0044 0.0106
Brugia malayi hypothetical protein 0.0159 0.0669 0.1614
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus tyrosine protein kinase Src64B 0.0119 0.0477 0.0477
Entamoeba histolytica tyrosin kinase, putative 0.0036 0.0074 0.0369
Trypanosoma brucei polo-like protein kinase 0.0302 0.1358 1
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus neuroglian 0.0048 0.0133 0.0133
Loa Loa (eye worm) serine/threonine protein kinase 0.0029 0.0042 0.0089
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0302 0.1358 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0119 0.0474 0.0474
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Loa Loa (eye worm) oxidoreductase 0.0031 0.0051 0.0107
Brugia malayi Variant SH3 domain containing protein 0.003 0.0047 0.0114
Brugia malayi Protein kinase domain containing protein 0.0323 0.1458 0.3519
Echinococcus granulosus lamin dm0 0.0026 0.0029 0.0029
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0029 0.0042 0.0183
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.132 0.9724
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0188 0.0188
Brugia malayi SH2 domain containing protein 0.0044 0.0116 0.028
Loa Loa (eye worm) hypothetical protein 0.0049 0.0136 0.0286
Echinococcus granulosus kinase suppressor of Ras 1 0.0029 0.0042 0.0042
Entamoeba histolytica protein kinase, putative 0.0078 0.0279 0.1905
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0091 0.0651
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Trichomonas vaginalis protein kinase atn1, putative 0.0029 0.0042 0.0183
Schistosoma mansoni aldo-keto reductase 0.0031 0.0051 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni ephrin receptor 0.0041 0.0098 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0027 0.0177
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Echinococcus granulosus cyclins 0.0037 0.0078 0.0078
Echinococcus granulosus cyclins 0.0037 0.0078 0.0078
Giardia lamblia Kinase, CMGC CDK 0.0098 0.0375 0.2625
Echinococcus granulosus epidermal growth factor receptor 0.0881 0.4143 0.4143
Schistosoma mansoni septate junction protein 0.0036 0.0077 0.0077
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0086 0.0209
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0044 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0782 0.1131
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0042 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Brugia malayi Immunoglobulin I-set domain containing protein 0.0759 0.3557 0.8586
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0165 0.0697 0.1461
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0188 0.0854
Echinococcus granulosus epidermal growth factor receptor 0.0597 0.2775 0.2775
Loa Loa (eye worm) TK/FAK protein kinase 0.0554 0.2567 0.5378
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0107
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0119 0.0119
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0324 0.0324
Giardia lamblia Aurora kinase 0.0241 0.1061 0.7773
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0029 0.0042 0.0089
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0119 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0048 0.0133 0.0278
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0188 0.1496
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0029 0.0042 0.0102
Echinococcus multilocularis tyrosine protein kinase HCK 0.0089 0.0331 0.0331
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.7257 0.7257
Echinococcus granulosus roundabout 2 0.0048 0.0133 0.0133
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Schistosoma mansoni lamin 0.0026 0.0029 0.0029
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni lamin 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Onchocerca volvulus 0.0031 0.0051 0.0071
Brugia malayi nuclear hormone receptor 0.0056 0.017 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni growth factor receptor-bound protein 0.003 0.0047 0.0047
Brugia malayi hypothetical protein 0.0031 0.0053 0.0128
Onchocerca volvulus 0.0026 0.0029 0.0001
Loa Loa (eye worm) AGC/AKT protein kinase 0.0078 0.0279 0.0583
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0042 0.0089
Onchocerca volvulus 0.0044 0.0116 0.0275
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0029 0.0029
Brugia malayi cytochrome P450 0.0021 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0309 0.1392 0.2915
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus bloom syndrome protein 0.0021 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0044 0.0092
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Schistosoma mansoni hypothetical protein 0.0029 0.0042 0.0042
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Entamoeba histolytica casein kinase, putative 0.0278 0.1241 0.9121
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0241 0.1061 0.4864
Onchocerca volvulus 0.0031 0.0051 0.0071
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0239 0.1054 0.1054
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0059 0.0187 0.0187
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0062 0.015
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0056 0.017 0.017
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0044 0.0106
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0782 0.1131
Trypanosoma cruzi cdc2-related kinase 3 0.0098 0.0375 0.2741
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0048 0.0133 0.0812
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0239 0.1054 0.1054
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0119 0.0474 0.0474
Schistosoma mansoni hypothetical protein 0.0027 0.0031 0.0031
Echinococcus granulosus glycoprotein Antigen 5 0.0031 0.0053 0.0053
Echinococcus granulosus ephrin type A receptor 4 A 0.0168 0.0712 0.0712
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0032 0.0055 0.0115
Echinococcus granulosus FTZ F1 alpha 0.0056 0.017 0.017
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0029 0.0029
Echinococcus granulosus peroxidasin 0.0036 0.0077 0.0077
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0042 0.0146
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0042 0.0102
Onchocerca volvulus 0.0029 0.0042 0.0043
Schistosoma mansoni single-minded 0.0047 0.0131 0.0131
Echinococcus multilocularis geminin 0.0165 0.0698 0.0698
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0189 0.0189
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Echinococcus multilocularis muscleblind protein 1 0.0297 0.1333 0.1333
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0091 0.0651
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0202 0.1466
Loa Loa (eye worm) TK/EGFR protein kinase 0.0881 0.4143 0.8679
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0165 0.0697 0.1461
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0278 0.1241 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0029 0.0042 0.0089
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0086 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0056 0.017 0.0411
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0042 0.0042
Brugia malayi hypothetical protein 0.0099 0.0378 0.0912
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0075 0.0265 0.0265
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0297 0.0716
Echinococcus multilocularis Glutaredoxin protein 5 0.0042 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0092
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Schistosoma mansoni serine/threonine-protein kinase 0.0057 0.0175 0.0175
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0056 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0055 0.0055
Brugia malayi Cytochrome P450 family protein 0.0038 0.0087 0.021
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0037 0.0078 0.0553
Echinococcus multilocularis beta adrenergic receptor kinase 0.0048 0.0135 0.0135
Onchocerca volvulus 0.0071 0.0243 0.0675
Brugia malayi Protein kinase domain containing protein 0.0044 0.0116 0.028
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0179 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0412 0.1882
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0029 0.006
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0048 0.0133 0.0957
Toxoplasma gondii STE kinase 0.0029 0.0042 0.0316
Brugia malayi PXA domain containing protein 0.0038 0.0086 0.0209
Schistosoma mansoni myosin-binding protein-related 0.0028 0.0035 0.0035
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0048 0.0133 0.0891
Loa Loa (eye worm) hypothetical protein 0.0037 0.0078 0.0164
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0048 0.0135 0.0327
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.0782 0.0782
Giardia lamblia Protein 21.1 0.0029 0.0042 0.0134
Echinococcus multilocularis serine:threonine protein kinase 38 0.0032 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0042 0.0105 0.0105
Echinococcus granulosus tumor protein p63 0.033 0.1489 0.1489
Echinococcus granulosus geminin 0.0165 0.0698 0.0698
Loa Loa (eye worm) sex muscle abnormal protein 5 0.003 0.0047 0.0099
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0124 0.082
Brugia malayi Pre-SET motif family protein 0.0415 0.1902 0.4591
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0375 0.171
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0182 0.0382
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0086 0.0209
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0048 0.0133 0.0957
Loa Loa (eye worm) hypothetical protein 0.0032 0.0055 0.0115
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Schistosoma mansoni tyrosine kinase 0.0059 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Plasmodium falciparum protein kinase, putative 0.0029 0.0042 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Brugia malayi PXA domain containing protein 0.0038 0.0086 0.0209
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0152 0.0633 0.0633
Brugia malayi Prion-like- 0.0036 0.0077 0.0185
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0029 0.0042 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni thyroid hormone receptor 0.0056 0.017 0.017
Echinococcus multilocularis raf serine:threonine protein kinase 0.0029 0.0042 0.0042
Entamoeba histolytica cyclin family protein 0.0037 0.0078 0.0403
Schistosoma mansoni thyroid hormone receptor 0.0056 0.017 0.017
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0074 0.0524
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0071 0.0172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.017 0.017
Schistosoma mansoni nck2/grb4 0.003 0.0047 0.0047
Echinococcus multilocularis c src tyrosine kinase 0.0059 0.0187 0.0187
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Onchocerca volvulus Protein ultraspiracle homolog 0.0056 0.017 0.0447
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Entamoeba histolytica protein kinase, putative 0.0241 0.1061 0.7773
Onchocerca volvulus 0.0029 0.0042 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Loa Loa (eye worm) hypothetical protein 0.0065 0.0213 0.0447
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0035 0.0073
Brugia malayi hypothetical protein 0.0038 0.0086 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Trichomonas vaginalis cyclin B3, putative 0.0037 0.0078 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Schistosoma mansoni titin 0.0036 0.0077 0.0077
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Loa Loa (eye worm) oxidoreductase 0.0031 0.0051 0.0107
Mycobacterium ulcerans hypothetical protein 0.0155 0.0649 0.0938
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Schistosoma mansoni tyrosine kinase 0.0044 0.0116 0.0116
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0047 0.0099
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0056 0.017 0.017
Schistosoma mansoni regulator of G protein signaling 0.004 0.0096 0.0096
Loa Loa (eye worm) TK protein kinase 0.0045 0.0119 0.0249
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0086 0.0086
Echinococcus multilocularis roundabout 2 0.0118 0.0471 0.0471
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0042 0.0042
Trichomonas vaginalis STE family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0584 0.2713 0.2713
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus ecdysone induced protein 78C 0.0056 0.017 0.017
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0203 0.1475
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Echinococcus granulosus tyrosine protein kinase Src42A 0.0075 0.0265 0.0265
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Trichomonas vaginalis cyclin D, putative 0.0037 0.0078 0.0348
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0032 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni RAR-like nuclear receptor 0.0056 0.017 0.017
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0584 0.2713 0.2713
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0037 0.0078 0.0078
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0044 0.0116 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0133 0.032
Schistosoma mansoni ephrin receptor 0.0141 0.0583 0.0583
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0044 0.0116 0.0275
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0051 0.0223
Onchocerca volvulus 0.0029 0.0042 0.0043
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0119 0.0477 0.0477
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0083 0.0372
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0573 0.4209
Brugia malayi follicle stimulating hormone receptor 0.0233 0.1024 0.2472
Toxoplasma gondii protein kinase 0.0029 0.0042 0.0316
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0191 0.0191
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0029 0.007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Trichomonas vaginalis TK family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0056 0.017 0.0357
Trypanosoma cruzi aurora B kinase, putative 0.0241 0.1061 0.7808
Echinococcus granulosus cyclin dependent kinase 1 0.0098 0.0375 0.0375
Brugia malayi Protein kinase domain containing protein 0.0098 0.0375 0.0904
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0086 0.0086
Echinococcus granulosus titin 0.0038 0.0084 0.0084
Echinococcus granulosus RUN 0.0119 0.0474 0.0474
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.0782 0.6294
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0048 0.0133 0.0133
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0029 0.0042 0.0042
Leishmania major casein kinase II, putative 0.0278 0.1241 0.9135
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0415 0.1902 0.3984
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0241 0.1061 0.7773
Loa Loa (eye worm) CAMK protein kinase 0.0038 0.0084 0.0176
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0071 0.0071
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0086 0.0086
Brugia malayi Cyclin, N-terminal domain containing protein 0.0037 0.0078 0.0189
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0042 0.0105 0.0105
Plasmodium falciparum casein kinase 2, alpha subunit 0.0278 0.1241 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis hemicentin 1 0.0036 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0056 0.017 0.0411
Onchocerca volvulus 0.0028 0.0035 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0029 0.0042 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0056 0.017 0.0357
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) TK/CSK protein kinase 0.0029 0.0042 0.0089
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0086 0.0086
Echinococcus granulosus lachesin 0.0036 0.0077 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Brugia malayi integrin-linked kinase 0.0029 0.0042 0.0102
Echinococcus granulosus plexin a4 0.0042 0.0105 0.0105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Loa Loa (eye worm) hypothetical protein 0.0062 0.0203 0.0425
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0042 0.0042
Leishmania major cathepsin L-like protease 0.0062 0.0202 0.1466
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Brugia malayi protein-tyrosine kinase 0.0104 0.0405 0.0977
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0074 0.0369
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0074 0.0156
Onchocerca volvulus 0.0037 0.0078 0.0156
Entamoeba histolytica protein kinase 2, putative 0.0052 0.0155 0.0975
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0055 0.0241
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0048 0.0133 0.0188
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0188 0.0188
Onchocerca volvulus 0.0044 0.0116 0.0275
Loa Loa (eye worm) hypothetical protein 0.0037 0.0078 0.0164
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0056 0.017 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0027 0.0177
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0032 0.0055 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0782 0.0782
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0136 0.0329
Brugia malayi glutathione reductase 0.0046 0.0124 0.03
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0769 0.3602 0.3602
Loa Loa (eye worm) SRC-1 0.0119 0.0477 0.0998
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Brugia malayi Protein kinase domain containing protein 0.0554 0.2567 0.6196
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0086 0.0086
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0212 0.0212
Echinococcus granulosus nervana 2 0.0042 0.0105 0.0105
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.007 0.0241 0.0241
Onchocerca volvulus 0.0031 0.0053 0.0078
Echinococcus granulosus tyrosine protein kinase Blk 0.0104 0.0405 0.0405
Loa Loa (eye worm) oxidoreductase 0.0031 0.0051 0.0107
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0104 0.0405 0.0405
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0086 0.0086
Trypanosoma brucei prostaglandin f synthase 0.0031 0.0051 0.0352
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Brugia malayi Protein kinase domain containing protein 0.0044 0.0116 0.028
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0032 0.0055 0.0055
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0027 0.0031 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0044 0.0106
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0188 0.0188
Echinococcus multilocularis Polycystic kidney disease protein 0.0119 0.0474 0.0474
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0032 0.0055 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0078 0.0279 0.1269
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0056 0.017 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Echinococcus multilocularis dna polymerase eta 0.0062 0.0203 0.0203
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0188 0.1229
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Plasmodium falciparum cysteine repeat modular protein 2 0.0027 0.0031 0.0054
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Brugia malayi Cytochrome P450 family protein 0.0021 0.0003 0.0008
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0083 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.0011 0.0055
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0042 0.0183
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0086 0.0086
Entamoeba histolytica hypothetical protein 0.0035 0.0071 0.035
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Plasmodium falciparum protein kinase, putative 0.0039 0.0091 0.055
Leishmania major cathepsin L-like protease 0.0062 0.0202 0.1466
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Brugia malayi hypothetical protein 0.0119 0.0474 0.1144
Echinococcus multilocularis neuroglian 0.0048 0.0133 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis cyclin A, putative 0.0037 0.0078 0.0348
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.0086
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0051 0.0223
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0759 0.3557 0.7451
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0074 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Brugia malayi Tyrosine-protein kinase abl-1 0.0059 0.0187 0.0453
Entamoeba histolytica PH domain containing protein kinase, putative 0.0057 0.0175 0.1128
Echinococcus multilocularis basement membrane specific heparan sulfate 0.007 0.0241 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0027 0.0177
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Echinococcus multilocularis thyroid hormone receptor alpha 0.0056 0.017 0.017
Brugia malayi p70 ribosomal S6 kinase beta 0.0074 0.0258 0.0623
Mycobacterium tuberculosis Conserved hypothetical protein 0.0048 0.0133 0.0195
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.0086
Brugia malayi C-terminal src kinase protein 1 0.0029 0.0042 0.0102
Trichomonas vaginalis cyclin B, putative 0.0037 0.0078 0.0348
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Onchocerca volvulus 0.0432 0.1982 0.6164
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Brugia malayi Protein kinase domain containing protein 0.0032 0.0055 0.0133
Echinococcus multilocularis cyclin dependent kinase 5 0.0098 0.0375 0.0375
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus granulosus cyclin B 0.0037 0.0078 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0375 0.0375
Trichomonas vaginalis cyclin D, putative 0.0037 0.0078 0.0348
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0087 0.0619
Loa Loa (eye worm) TK/ABL protein kinase 0.0044 0.0116 0.0243
Schistosoma mansoni rab6-interacting 0.0119 0.0474 0.0474
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0086 0.0181
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0409 0.0609
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0023 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Leishmania major DNA polymerase eta, putative 0.0062 0.0203 0.1475
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0102 0.0726
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0124 0.026
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0048 0.0133 0.0133
Trypanosoma cruzi polo-like protein kinase, putative 0.0302 0.1358 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0153 0.0321
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0188 0.0854
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0044 0.0116 0.0685
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Brugia malayi Protein kinase domain containing protein 0.0044 0.0116 0.028
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0086 0.0086
Toxoplasma gondii hypothetical protein 0.0027 0.0031 0.0225
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0031 0.0075
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.0086
Loa Loa (eye worm) AUR protein kinase 0.0241 0.1061 0.2222
Echinococcus granulosus tyrosine protein kinase 0.0029 0.0042 0.0042
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0029 0.0042 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus natriuretic peptide receptor 1 0.0029 0.0042 0.0042
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.0782 0.0782
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0042 0.0146
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.0782 0.117
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0029 0.0042 0.0042
Giardia lamblia Aldose reductase 0.0031 0.0051 0.0199
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0032 0.0055 0.0115
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Brugia malayi Thioredoxin reductase 0.0046 0.0124 0.03
Plasmodium vivax SET domain protein, putative 0.006 0.0189 0.1353
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0057 0.0175 0.1267
Echinococcus multilocularis FL cytokine receptor 0.0029 0.0042 0.0042
Echinococcus multilocularis enteropeptidase 0.0031 0.0053 0.0053
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0212 0.0512
Entamoeba histolytica protein kinase, putative 0.0032 0.0055 0.0228
Echinococcus multilocularis aldo keto reductase 0.0031 0.0051 0.0051
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0048 0.0133 0.0812
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0155 0.1117
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Echinococcus granulosus aldo keto reductase 0.0031 0.0051 0.0051
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0133 0.032
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1239 0.1239
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0031 0.0054
Brugia malayi nuclear receptor NHR-88 0.0026 0.0029 0.0069
Schistosoma mansoni hypothetical protein 0.0031 0.0053 0.0053
Loa Loa (eye worm) AGC/NDR protein kinase 0.0032 0.0055 0.0115
Schistosoma mansoni kinase 0.0436 0.2 0.2
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0031 0.0053 0.0053
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0074 0.0074
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0029 0.0042 0.0043
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.003 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi MAP kinase sur-1 0.0059 0.0188 0.0455
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0197 0.0851 0.0851
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0086 0.0086
Brugia malayi PAS domain containing protein 0.0047 0.0131 0.0315
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0042 0.0042
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0029 0.0042 0.0288
Loa Loa (eye worm) cyclin domain-containing protein 0.0037 0.0078 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0056 0.017 0.0357
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0029 0.0069
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0212 0.1543
Trichomonas vaginalis cyclins, putative 0.0037 0.0078 0.0348
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0032 0.0055 0.0115
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Schistosoma mansoni growth factor receptor-bound protein 0.003 0.0047 0.0047
Onchocerca volvulus Serine\/threonine kinase homolog 0.0302 0.1358 0.4194
Schistosoma mansoni retinoic acid receptor RXR 0.0152 0.0633 0.0633
Toxoplasma gondii protein kinase domain-containing protein 0.0029 0.0042 0.0316
Brugia malayi Steroid receptor seven-up type 2 0.0056 0.017 0.0411
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Echinococcus multilocularis transfer RNA-Phe 0.0028 0.0035 0.0035
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0052 0.0155 0.0155
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0048 0.0133 0.0957
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0002 0.0002
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0042 0.0316
Echinococcus multilocularis neuroglian 0.0086 0.0317 0.0317
Giardia lamblia Kinase, PLK 0.0302 0.1358 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0098 0.0375 0.0375
Onchocerca volvulus Bile acid receptor homolog 0.0056 0.017 0.0447
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0048 0.0133 0.0321
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0029 0.0042 0.0042
Onchocerca volvulus 0.0027 0.0033 0.0013
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0086 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Echinococcus multilocularis integrin linked protein kinase 0.0029 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.017 0.0411
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Brugia malayi Trypsin family protein 0.0031 0.0053 0.0128
Leishmania major cyclin 0.0037 0.0078 0.0553
Schistosoma mansoni tyrosine kinase 0.0065 0.0217 0.0217
Onchocerca volvulus 0.0112 0.0443 0.1308
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Brugia malayi hypothetical protein 0.0029 0.0044 0.0106
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Echinococcus granulosus single minded 2 0.0035 0.0071 0.0071
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0035 0.0073
Onchocerca volvulus 0.0056 0.017 0.0447
Loa Loa (eye worm) hypothetical protein 0.0106 0.0415 0.0869
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0037 0.0078 0.0078
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0086 0.0209
Schistosoma mansoni protein kinase 0.0197 0.0851 0.0851
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0136 0.0329
Brugia malayi Protein kinase domain containing protein 0.0165 0.0697 0.1683
Trypanosoma brucei Casein kinase II 0.0278 0.1241 0.9135
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0191 0.0461
Onchocerca volvulus 0.0044 0.0116 0.0275
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0048 0.0133 0.0891
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Echinococcus multilocularis protein kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0029 0.0029
Trypanosoma cruzi cdc2-related kinase 3 0.0098 0.0375 0.2741
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0086 0.0209
Trypanosoma brucei unspecified product 0.0026 0.0027 0.0177
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0052 0.0155 0.1069
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.1012 0.4774 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0042 0.0042
Loa Loa (eye worm) AUR protein kinase 0.0241 0.1061 0.2222
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0412 0.1882
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase HCK 0.0089 0.0331 0.0331
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0036 0.0077 0.0151
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni steroid hormone receptor ad4bp 0.0056 0.017 0.017
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0048 0.0133 0.0133
Leishmania major protein kinase, putative 0.0039 0.0091 0.0651
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Brugia malayi plexin A 0.0042 0.0105 0.0253
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0051 0.0123
Schistosoma mansoni tyrosine kinase 0.0757 0.3546 0.3546
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0031 0.0051 0.0352
Loa Loa (eye worm) plexin A 0.0042 0.0105 0.022
Loa Loa (eye worm) glutathione reductase 0.0046 0.0124 0.026
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Leishmania major cathepsin L-like protease 0.0062 0.0202 0.1466
Plasmodium vivax unspecified product 0.0278 0.1241 1
Echinococcus granulosus serine threonine protein kinase nrc 0.0052 0.0155 0.0155
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0087 0.0619
Echinococcus multilocularis endonuclease reverse transcriptase 0.0027 0.0031 0.0031
Echinococcus multilocularis activin receptor type 0.0039 0.0091 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0027 0.0031 0.0054
Plasmodium falciparum protein kinase 5 0.0098 0.0375 0.2878
Toxoplasma gondii hypothetical protein 0.0028 0.0036 0.0263
Loa Loa (eye worm) hypothetical protein 0.0099 0.0378 0.0791
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.0181
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Loa Loa (eye worm) TK protein kinase 0.0104 0.0405 0.0848
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0465 0.0694
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Echinococcus granulosus tyrosine protein kinase Lyn 0.0129 0.0526 0.0526
Echinococcus multilocularis lachesin 0.0036 0.0077 0.0077
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0025 0.0101
Schistosoma mansoni tyrosine kinase 0.0597 0.2775 0.2775
Brugia malayi Tyrosine-protein kinase PR2 0.0029 0.0042 0.0102
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0098 0.0375 0.2741
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0048 0.0133 0.0133
Echinococcus granulosus tyrosine protein kinase pr2 0.0029 0.0042 0.0042
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0048 0.0133 0.0133
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0294 0.1318 0.276
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0191 0.0191
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0098 0.0375 0.0784
Brugia malayi Trypsin family protein 0.0031 0.0053 0.0128
Entamoeba histolytica protein kinase, putative 0.0025 0.0025 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0189 0.0189
Loa Loa (eye worm) TK protein kinase 0.0029 0.0042 0.0089
Plasmodium falciparum cysteine repeat modular protein 3 0.0027 0.0031 0.0054
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0048 0.0133 0.0599
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0212 0.0212
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Entamoeba histolytica protein kinase, putative 0.0074 0.0258 0.1753
Brugia malayi Protein kinase domain containing protein 0.0032 0.0055 0.0133
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0074 0.0524
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0074 0.0409
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0083 0.0372
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0029 0.0029
Trypanosoma cruzi protein kinase, putative 0.0029 0.0042 0.0288
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.1241 0.569
Echinococcus granulosus contactin 0.0048 0.0133 0.0133
Entamoeba histolytica protein kinase, putative 0.0037 0.008 0.0417
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0051 0.0123
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Echinococcus multilocularis growth factor receptor bound protein 2 0.003 0.0047 0.0047
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0042 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0008 0.0007
Plasmodium falciparum protein kinase, putative 0.0029 0.0042 0.0146
Brugia malayi hypothetical protein 0.0082 0.0297 0.0716
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0056 0.017 0.017
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Entamoeba histolytica hypothetical protein 0.0035 0.0071 0.035
Trypanosoma cruzi aldo-keto reductase 0.0031 0.0051 0.0352
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0119 0.0477 0.0477
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0241 0.1061 0.7773
Loa Loa (eye worm) projectin 0.0028 0.0035 0.0073
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis tyrosine protein kinase pr2 0.0029 0.0042 0.0042
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0083 0.0083
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0025 0.0025 0.0002
Loa Loa (eye worm) cytochrome P450 0.0021 0.0003 0.0007
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0071 0.0071
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0104 0.0405 0.0405
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Brugia malayi hypothetical protein 0.0038 0.0086 0.0209
Echinococcus multilocularis aldo keto reductase 0.0031 0.0051 0.0051
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0083 0.0592
Brugia malayi Raf kinase 0.0029 0.0042 0.0102
Schistosoma mansoni lipoxygenase 0.0584 0.2713 0.2713
Echinococcus multilocularis cyclin dependent kinase 1 0.0098 0.0375 0.0375
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0191 0.0191
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0197 0.0851 0.0851
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0029 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.1358 0.1358
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0098 0.0375 0.0375
Schistosoma mansoni cell adhesion molecule 0.0036 0.0077 0.0077
Toxoplasma gondii AGC kinase 0.0074 0.0258 0.206
Echinococcus granulosus intermediate filament protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Brugia malayi Furin-like cysteine rich region family protein 0.0881 0.4143 1
Echinococcus granulosus cyclin B3 1 0.0037 0.0078 0.0078
Trichomonas vaginalis cyclins, putative 0.0037 0.0078 0.0348
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni hypothetical protein 0.0035 0.0071 0.0071
Echinococcus multilocularis aldehyde reductase 0.0022 0.0008 0.0008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0188 0.0395
Echinococcus granulosus raf serine:threonine protein kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0044 0.0116 0.0116
Entamoeba histolytica cysteine surface protein, putative 0.0029 0.0042 0.0134
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0378 0.0912
Schistosoma mansoni flap endonuclease-1 0.0023 0.0013 0.0013
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0082 0.0082
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0051 0.0051
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0212 0.0212
Echinococcus granulosus activin receptor type 0.0039 0.0091 0.0091
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Entamoeba histolytica cysteine-rich surface protein, putative 0.0027 0.0031 0.005
Loa Loa (eye worm) RecQ helicase 0.0021 0.0002 0.0005
Brugia malayi Cytochrome P450 family protein 0.0058 0.0182 0.044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0056 0.0135
Brugia malayi Protein kinase domain containing protein 0.0044 0.0116 0.028
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0243 0.0243
Echinococcus granulosus NDR protein kinase 0.0032 0.0055 0.0055
Entamoeba histolytica protein kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis transfer RNA-Thr 0.0029 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0124 0.0124
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0042 0.0102
Echinococcus multilocularis expressed protein 0.0745 0.3489 0.3489
Leishmania major protein kinase, putative 0.0241 0.1061 0.7808
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0782 0.0782
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Brugia malayi nuclear receptor NHR-88 0.0056 0.017 0.0411
Echinococcus multilocularis rac serine:threonine kinase 0.0057 0.0175 0.0175
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Leishmania major trypanothione reductase 0.0046 0.0124 0.0893
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0077 0.0185
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0048 0.0133 0.0278
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0074 0.0373
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.006
Echinococcus granulosus Protein kinase C brain isozyme 0.0032 0.0055 0.0055
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0083 0.0116
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0212 0.1543
Brugia malayi Flap endonuclease-1 0.0025 0.0025 0.0059
Trypanosoma cruzi Protein kinase B 0.0057 0.0175 0.1267
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0086 0.0086
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0042 0.0102
Loa Loa (eye worm) hypothetical protein 0.0297 0.1333 0.2792
Echinococcus multilocularis twitchin 0.0026 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0065
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0324 0.0324
Giardia lamblia Aldose reductase 0.0031 0.0051 0.0199
Brugia malayi Cyclin, N-terminal domain containing protein 0.0037 0.0078 0.0189
Loa Loa (eye worm) TK/FER protein kinase 0.0044 0.0116 0.0243
Echinococcus granulosus integrin linked protein kinase 0.0029 0.0042 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0042 0.0134
Brugia malayi intermediate filament protein 0.0026 0.0029 0.007
Echinococcus granulosus insulin receptor 0.0757 0.3546 0.3546
Schistosoma mansoni roundabout 0.0036 0.0077 0.0077
Echinococcus multilocularis cyclin B 0.0037 0.0078 0.0078
Brugia malayi serine/threonine protein kinase 6 0.0241 0.1061 0.256
Schistosoma mansoni titin 0.0028 0.0035 0.0035
Brugia malayi Muscleblind-like protein 0.0297 0.1333 0.3217
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0042 0.0134
Schistosoma mansoni tyrosine protein kinase 0.0029 0.0042 0.0042
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0003 0.0003
Loa Loa (eye worm) AGC/PKN protein kinase 0.0032 0.0055 0.0115
Schistosoma mansoni septate junction protein 0.0036 0.0077 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Onchocerca volvulus 0.0031 0.0053 0.0078
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0477 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.017 0.0411
Echinococcus multilocularis Immunoglobulin 0.007 0.0241 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0135 0.0135
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0119 0.0477 0.0477
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0042 0.0146
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0202 0.1466
Echinococcus granulosus roundabout 2 0.0118 0.0471 0.0471
Entamoeba histolytica hypothetical protein 0.0038 0.0086 0.0464
Echinococcus multilocularis insulin receptor 0.0757 0.3546 0.3546
Trypanosoma cruzi cdc2-related kinase 1 0.0098 0.0375 0.2741
Echinococcus granulosus serine:threonine protein kinase N2 0.0032 0.0055 0.0055
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0203 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1358 0.6228
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.017 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0202 0.1466
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0004
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0029 0.0069
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0029 0.0042 0.0089
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0091 0.0338 0.0338
Schistosoma mansoni tyrosine kinase 0.0059 0.0187 0.0187
Schistosoma mansoni tyrosine kinase 0.0119 0.0477 0.0477
Trichomonas vaginalis cyclins, putative 0.0037 0.0078 0.0348
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0212 0.1408
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Onchocerca volvulus 0.0031 0.0053 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.0056 0.017 0.0411
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0091 0.0501
Echinococcus granulosus NCK adaptor protein 0.003 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0027 0.0031 0.005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0089
Loa Loa (eye worm) AUR protein kinase 0.0241 0.1061 0.2222
Echinococcus multilocularis tyrosine kinase 0.0044 0.0116 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0241 0.1061 0.4864
Echinococcus multilocularis glycoprotein Antigen 5 0.0031 0.0053 0.0053
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0029 0.0029
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0086 0.0086
Echinococcus granulosus titin 0.0038 0.0084 0.0084
Echinococcus granulosus casein kinase ii subunit alpha 0.0278 0.1241 0.1241
Onchocerca volvulus 0.0031 0.0051 0.0071
Plasmodium falciparum cysteine repeat modular protein 4 0.0027 0.0031 0.0054
Echinococcus granulosus growth factor receptor bound protein 2 0.003 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Giardia lamblia Kinase, CMGC CDK 0.0098 0.0375 0.2625
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0042 0.0134
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.132 0.9724
Loa Loa (eye worm) hypothetical protein 0.0056 0.017 0.0357
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0119 0.0477 0.0477
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0074 0.0409
Brugia malayi hypothetical protein 0.0026 0.0029 0.0069
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0119 0.0119
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0029 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0042 0.0089
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0032 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0042 0.0042
Trichomonas vaginalis cyclins, putative 0.0037 0.0078 0.0348
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0042 0.0089
Trypanosoma brucei mitotic cyclin 6 0.0037 0.0078 0.0553
Trichomonas vaginalis cyclin B, putative 0.0037 0.0078 0.0348
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0074 0.0373
Entamoeba histolytica protein kinase, putative 0.0241 0.1061 0.7773
Schistosoma mansoni tyrosine kinase 0.0029 0.0042 0.0042
Echinococcus multilocularis peroxidasin 0.0036 0.0077 0.0077
Schistosoma mansoni protein kinase 0.0241 0.1061 0.1061
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0031 0.0075
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0029 0.0042 0.0042
Onchocerca volvulus 0.0044 0.0116 0.0275
Brugia malayi Protein kinase domain containing protein 0.0044 0.0116 0.028
Loa Loa (eye worm) hypothetical protein 0.0106 0.0415 0.0869
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0055 0.0241
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0241 0.1061 0.1061
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0038 0.0084 0.0176
Loa Loa (eye worm) hypothetical protein 0.006 0.0189 0.0396
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0035 0.0084
Entamoeba histolytica aldose reductase, putative 0.0031 0.0051 0.0199
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0074 0.0524
Trichomonas vaginalis cyclins, putative 0.0037 0.0078 0.0348
Loa Loa (eye worm) TK protein kinase 0.0089 0.0331 0.0694
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Echinococcus granulosus aurora kinase A 0.0241 0.1061 0.1061
Plasmodium falciparum thioredoxin reductase 0.0046 0.0124 0.082
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.1061 0.1061
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0031 0.0053 0.0053
Entamoeba histolytica protein kinase domain containing protein 0.0241 0.1061 0.7773
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0048 0.0134 0.0282
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Loa Loa (eye worm) doublecortin family protein 0.0119 0.0474 0.0993
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0028 0.0028
Schistosoma mansoni protein tyrosine kinase 0.0029 0.0042 0.0042
Trichomonas vaginalis protein tyrosine kinase, putative 0.0029 0.0042 0.0183
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0042 0.0042
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0029 0.0042 0.0183
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0078 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Trichomonas vaginalis AGC family protein kinase 0.0241 0.1061 0.4864
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0031 0.0053 0.0053
Echinococcus granulosus flap endonuclease 1 0.0025 0.0025 0.0025
Schistosoma mansoni lozenge 0.0054 0.0163 0.0163
Echinococcus multilocularis cyclins 0.0037 0.0078 0.0078
Echinococcus multilocularis lipoxygenase domain containing protein 0.0119 0.0474 0.0474
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0087 0.0619
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0051 0.0223
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0048 0.0133 0.0133
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0056
Echinococcus multilocularis protein KINase family member (kin 25) 0.0029 0.0042 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0083 0.0592
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0145 0.1048
Schistosoma mansoni tyrosine kinase 0.0757 0.3546 0.3546
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0051 0.0123
Echinococcus multilocularis activated cdc42 kinase 1 0.0029 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0042 0.0042
Echinococcus multilocularis tyrosine protein kinase Blk 0.0104 0.0405 0.0405
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0029 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0112
Echinococcus granulosus neuroglian 0.0086 0.0317 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0086 0.0386
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0212 0.0445
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0134 0.0134
Entamoeba histolytica hypothetical protein 0.0029 0.0042 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0135 0.0135
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0042 0.0134
Giardia lamblia Kinase, NEK 0.0029 0.0042 0.0134
Onchocerca volvulus 0.0473 0.2178 0.6783
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.017 0.0411
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0051 0.0223
Brugia malayi serine/threonine-protein kinase plk-2 0.0302 0.1358 0.3277
Loa Loa (eye worm) hypothetical protein 0.0099 0.0378 0.0791
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0051 0.0051
Echinococcus granulosus transmembrane protease serine 3 0.0031 0.0053 0.0053
Schistosoma mansoni protein kinase 0.0029 0.0042 0.0042
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0074 0.0258 0.0541
Echinococcus granulosus dna polymerase eta 0.0062 0.0203 0.0203
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.016
Brugia malayi Hr1 repeat family protein 0.0032 0.0055 0.0133
Schistosoma mansoni cercarial elastase (S01 family) 0.0031 0.0053 0.0053
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0074 0.033
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.017 0.0411
Plasmodium falciparum cyclin 0.0037 0.0078 0.0442
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0233 0.1024 0.2146

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1.5 nM Inhibitory activity against HIV-1 protease ChEMBL. 14643311
Ki (binding) = 1.5 nM Inhibitory activity against HIV-1 protease ChEMBL. 14643311

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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