Detailed information for compound 280913

Basic information

Technical information
  • TDR Targets ID: 280913
  • Name: 3-amino-2-(1H-indol-3-yl)propanoic acid
  • MW: 204.225 | Formula: C11H12N2O2
  • H donors: 3 H acceptors: 2 LogP: -1.67 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCC(c1c[nH]c2c1cccc2)C(=O)O
  • InChi: 1S/C11H12N2O2/c12-5-8(11(14)15)9-6-13-10-4-2-1-3-7(9)10/h1-4,6,8,13H,5,12H2,(H,14,15)
  • InChiKey: PVUWKCFXEZIILU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-azanyl-2-(1H-indol-3-yl)propanoic acid
  • 3-amino-2-(1H-indol-3-yl)propionic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Echinococcus granulosus JmjC domain containing protein 4 0.0044 0.0104 0.0196
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0025 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.126 0.4531 0.6451
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0009 0.0023
Loa Loa (eye worm) inositol-1 0.0041 0.0094 0.0279
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0079 0.0357
Echinococcus multilocularis follistatin 0.008 0.0237 0.0237
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0114 0.0361 0.1634
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0114 0.0361 0.0684
Plasmodium vivax glutathione reductase, putative 0.0556 0.1969 1
Entamoeba histolytica disulphide oxidoreductase, putative 0.0114 0.0361 0.1605
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1104 0.3961 0.564
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0114 0.0361 0.0983
Schistosoma mansoni hypothetical protein 0.0043 0.01 0.0189
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0035 0.0104
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0255 0.1255
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.126 0.4531 0.6451
Brugia malayi MAP kinase sur-1 0.0108 0.0338 0.1004
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.0166
Leishmania major NADH dehydrogenase, putative 0.0114 0.0361 0.0514
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0057 0.0169
Schistosoma mansoni zinc finger protein 0.0031 0.0057 0.0108
Trichomonas vaginalis taga, putative 0.0022 0.0025 0.0111
Schistosoma mansoni sulfide quinone reductase 0.0114 0.0361 0.0684
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0431 0.1514 0.2156
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0109 0.0206
Onchocerca volvulus Glucosylceramidase homolog 0.0188 0.063 0.185
Onchocerca volvulus Putative organic anion transporter 0.0118 0.0373 0.1083
Echinococcus multilocularis glutamate synthase 0.0114 0.0361 0.0361
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0231 0.0786 0.1488
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0035 0.007 0.01
Brugia malayi TAR-binding protein 0.0067 0.0188 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0083 0.0156
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0037
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0114 0.0361 0.0514
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0431 0.1514 0.9948
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0083 0.0224
Trypanosoma cruzi metacaspase, putative 0.0019 0.0012 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.002 0.006
Brugia malayi prostaglandin transporter 0.0118 0.0373 0.1105
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Brugia malayi Bromodomain containing protein 0.0032 0.0062 0.0185
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0009 0.0016
Trichomonas vaginalis glutamate synthase, putative 0.0114 0.0361 0.1634
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0039 0.0198
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0025 0.0076
Echinococcus multilocularis jun protein 0.0093 0.0284 0.0284
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0035 0.0096
Onchocerca volvulus 0.0118 0.0373 0.1083
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0025 0.0076
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0041 0.0058
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0039 0.0155
Loa Loa (eye worm) runx1 0.0118 0.0374 0.111
Echinococcus granulosus lamin 0.003 0.0054 0.0101
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0057 0.0108
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0083 0.0224
Leishmania major hypothetical protein, conserved 0.0114 0.0361 0.0514
Brugia malayi jmjC domain containing protein 0.0044 0.0104 0.0307
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0431 0.1514 0.9948
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0083 0.0118
Onchocerca volvulus 0.0118 0.0373 0.1083
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.007 0.0133
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0431 0.1514 0.2156
Brugia malayi Smad1 0.0025 0.0035 0.0104
Trichomonas vaginalis abcb9, putative 0.0022 0.0025 0.0111
Brugia malayi hypothetical protein 0.0043 0.01 0.0296
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0025 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.007 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.002 0.0089
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0093 0.0284 0.0538
Mycobacterium tuberculosis Probable oxidoreductase 0.0431 0.1514 0.4123
Echinococcus granulosus neuropeptide s receptor 0.052 0.1836 0.3476
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.007 0.007
Loa Loa (eye worm) cysteine protease 0.0018 0.0009 0.0026
Schistosoma mansoni organic anion transporter 0.0118 0.0373 0.0705
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0012 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0066 0.0183 0.0543
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0114 0.0361 0.0514
Chlamydia trachomatis thioredoxin reductase 0.0114 0.0361 0.231
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0105
Echinococcus granulosus dnaJ subfamily B 0.0869 0.3108 0.5884
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0094 0.0422
Brugia malayi Pre-SET motif family protein 0.0064 0.0178 0.0528
Echinococcus granulosus survival motor neuron protein 1 0.0263 0.0902 0.1707
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Loa Loa (eye worm) ctsf protein 0.0018 0.0009 0.0026
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0087 0.026 0.1281
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0104 0.0308
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Onchocerca volvulus 0.0077 0.0224 0.0642
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0338 0.0482
Onchocerca volvulus Putative organic anion transporter 0.0118 0.0373 0.1083
Echinococcus multilocularis Protein lozenge 0.0118 0.0374 0.0374
Schistosoma mansoni cpg binding protein 0.0061 0.0166 0.0315
Echinococcus multilocularis pol protein 0.2762 1 1
Onchocerca volvulus Bile acid receptor homolog 0.0066 0.0183 0.0519
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0188 0.0355
Onchocerca volvulus 0.0038 0.0083 0.022
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0083 0.038
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Brugia malayi SET domain containing protein 0.0016 0.0004 0.0011
Schistosoma mansoni glutaminase 0.0288 0.0994 0.1882
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.008 0.0237 0.0702
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.126 0.4531 0.6451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.0424 0.0803
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0338 0.1532
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0255 0.1255
Brugia malayi tailless protein 0.0031 0.0057 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0037
Echinococcus multilocularis chromobox protein 1 0.0077 0.0226 0.0226
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0114 0.0361 0.0983
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0037
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0065 0.029
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0114 0.0361 0.1833
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0056 0.0251
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0025 0.0048
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0227 0.043
Brugia malayi PHD-finger family protein 0.0032 0.0062 0.0185
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.002 0.006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0215 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0226 0.1023
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0104 0.0308
Leishmania major metacaspase, putative 0.0019 0.0012 0.0017
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0025 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0083 0.0377
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0034 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0041 0.0181
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0025 0.0025
Entamoeba histolytica thioredoxin reductase, putative 0.0114 0.0361 0.1605
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0044 0.0104 0.0527
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0026 0.0052
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0361 0.0983
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0054 0.0158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.0183 0.0183
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0114 0.0361 0.1605
Loa Loa (eye worm) hypothetical protein 0.0137 0.0444 0.1316
Mycobacterium ulcerans dehydrogenase 0.0114 0.0361 0.0983
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0083 0.0083
Echinococcus granulosus intermediate filament protein 0.003 0.0054 0.0101
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0431 0.1514 0.768
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0035 0.007 0.007
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0079 0.0357
Treponema pallidum NAD synthetase 0.0087 0.026 0.1095
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0083 0.0224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1494 0.5381 0.7662
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0057 0.0144
Echinococcus granulosus follistatin 0.008 0.0237 0.0448
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Trypanosoma cruzi metacaspase, putative 0.0019 0.0012 0.0017
Giardia lamblia PHD finger protein 15 0.0032 0.0062 0.0192
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0076
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0094 0.0489
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0114 0.0361 0.1833
Echinococcus multilocularis pol protein 0.2762 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.002 0.0029
Giardia lamblia NH3-dependent NAD+ synthetase 0.0087 0.026 0.1095
Schistosoma mansoni chromobox protein 0.0077 0.0226 0.0429
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0041 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Toxoplasma gondii hypothetical protein 0.0314 0.1086 0.5515
Mycobacterium ulcerans endonuclease IV 0.0085 0.0255 0.0693
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.126 0.4531 0.6451
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0039 0.0106
Giardia lamblia Fructose-bisphosphate aldolase 0.0621 0.2205 1
Onchocerca volvulus 0.0092 0.0281 0.081
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0035 0.0067
Echinococcus granulosus caspase 0.0019 0.0012 0.0023
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1494 0.5381 0.7662
Schistosoma mansoni lipoxygenase 0.0113 0.0354 0.067
Echinococcus granulosus biogenic amine 5HT receptor 0.0143 0.0466 0.0883
Loa Loa (eye worm) hypothetical protein 0.0143 0.0466 0.1383
Loa Loa (eye worm) hypothetical protein 0.0317 0.11 0.3263
Entamoeba histolytica hypothetical protein 0.0074 0.0215 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0207 0.0391
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0039 0.0198
Toxoplasma gondii selenide, water dikinase 0.0114 0.0361 0.1833
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0066 0.0183 0.0346
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0025 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0114 0.0361 0.0684
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.008 0.0237 0.0702
Schistosoma mansoni hypothetical protein 0.0735 0.2618 0.4957
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0153
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.0183 0.0346
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0207 0.0391
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.002 0.0029
Trypanosoma cruzi NADH dehydrogenase, putative 0.0114 0.0361 0.0514
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0083 0.038
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Brugia malayi hypothetical protein 0.0118 0.0373 0.1105
Mycobacterium tuberculosis Conserved protein 0.0038 0.0083 0.0224
Onchocerca volvulus 0.0043 0.0103 0.0279
Echinococcus multilocularis jumonji domain containing 1A 0.0044 0.0104 0.0104
Mycobacterium ulcerans ferredoxin reductase 0.0114 0.0361 0.0983
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0025 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Brugia malayi Protein kinase domain containing protein 0.0016 0.0003 0.0009
Onchocerca volvulus 0.0054 0.014 0.039
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.01 0.01
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Onchocerca volvulus 0.0061 0.0166 0.047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0104 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Schistosoma mansoni smad1 5 8 and 0.0025 0.0035 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Brugia malayi SPARC precursor 0.008 0.0237 0.0702
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0083 0.0117
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0317 0.1098 0.3256
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.0338 0.0482
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0103 0.0194
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0066 0.0183 0.0346
Trypanosoma cruzi trypanothione reductase, putative 0.0431 0.1514 0.2156
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0431 0.1514 0.768
Echinococcus granulosus glutamate synthase 0.0114 0.0361 0.0684
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0054 0.0159
Brugia malayi Cytochrome P450 family protein 0.0035 0.0073 0.0217
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0079 0.0112
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0175 0.0332
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0188 0.0557
Onchocerca volvulus 0.0941 0.337 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0114 0.0361 0.0983
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Trypanosoma brucei NAD+ synthase, putative 0.0087 0.026 0.037
Mycobacterium tuberculosis Conserved protein 0.0038 0.0083 0.0224
Loa Loa (eye worm) hypothetical protein 0.0063 0.0175 0.0521
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0114 0.0361 0.0361
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0057 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0066 0.0183 0.0543
Schistosoma mansoni smdr2 0.0022 0.0025 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.0183 0.0542
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0433 0.1522 0.6875
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.0338 0.0482
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0057 0.0057
Echinococcus multilocularis smad 0.0025 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0068 0.0203
Onchocerca volvulus 0.0043 0.01 0.0271
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.0183 0.0183
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0009 0.0016
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0008 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0066 0.0183 0.0543
Trypanosoma brucei RNA helicase, putative 0.0103 0.0319 0.0454
Mycobacterium tuberculosis Conserved protein 0.0038 0.0083 0.0224
Echinococcus granulosus chromobox protein 1 0.0077 0.0226 0.0429
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0338 0.0639
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0226 0.1023
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0066 0.0183 0.0346
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Trypanosoma brucei metacaspase MCA3 0.0019 0.0012 0.0017
Trypanosoma brucei Metacaspase-4 0.0019 0.0012 0.0017
Toxoplasma gondii exonuclease III APE 0.0021 0.002 0.0104
Echinococcus multilocularis muscleblind protein 1 0.0317 0.11 0.11
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0189 0.0269
Brugia malayi MH2 domain containing protein 0.0025 0.0035 0.0104
Trypanosoma cruzi NADH dehydrogenase, putative 0.0114 0.0361 0.0514
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0431 0.1514 0.769
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0062 0.0317
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0057 0.0108
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0052 0.0134 0.0253
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0431 0.1514 0.768
Mycobacterium ulcerans beta-lactamase 0.0038 0.0083 0.0224
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.01 0.01
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0062 0.017 0.0506
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0114 0.0361 0.1634
Echinococcus granulosus cathepsin l1 0.0018 0.0009 0.0016
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0025 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0094 0.0133
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0621 0.2205 1
Echinococcus multilocularis pol protein 0.2762 1 1
Toxoplasma gondii ABC1 family protein 0.0038 0.0083 0.0419
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0021 0.0021
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0062 0.0185
Leishmania major hypothetical protein, conserved 0.0114 0.0361 0.0514
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0039 0.0177
Schistosoma mansoni jumonji/arid domain-containing protein 0.0168 0.0555 0.105
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0039 0.0123
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0025 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0035 0.0096
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0065 0.0093
Trichomonas vaginalis glutaminase, putative 0.0288 0.0994 0.4506
Brugia malayi hypothetical protein 0.0043 0.01 0.0296
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0057 0.0057
Loa Loa (eye worm) heterochromatin protein 1 0.0077 0.0226 0.0672
Schistosoma mansoni retinoic acid receptor RXR 0.017 0.0562 0.1063
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0066 0.0183 0.0542
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0085 0.0255 0.0755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Echinococcus granulosus chromobox protein 1 0.0077 0.0226 0.0429
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0083 0.0542
Onchocerca volvulus 0.0031 0.0057 0.0144
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.012 0.0356
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Loa Loa (eye worm) steroid hormone receptor 0.0066 0.0183 0.0543
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0024 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1945 0.7023 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0338 0.0639
Brugia malayi MH2 domain containing protein 0.0025 0.0035 0.0104
Brugia malayi ABC transporter family protein 0.0022 0.0025 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0431 0.1514 0.768
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0065 0.0065
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1945 0.7023 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.002 0.0039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0034 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0035 0.0104
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Giardia lamblia Glutamate synthase 0.0114 0.0361 0.1559
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0083 0.0371
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.007 0.0133
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.008 0.0237 0.0702
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.0338 0.1004
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0433 0.1522 1
Schistosoma mansoni hypothetical protein 0.0054 0.014 0.0264
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0338 0.1532
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0102 0.0461
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0039 0.0055
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0227 0.0227
Leishmania major cytochrome p450-like protein 0.0025 0.0034 0.0048
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0281 0.0532
Chlamydia trachomatis endonuclease IV 0.0085 0.0255 0.1605
Treponema pallidum thioredoxin reductase (trxB) 0.0114 0.0361 0.1559
Giardia lamblia NADH oxidase lateral transfer candidate 0.0431 0.1514 0.6839
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0433 0.1522 0.4144
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Schistosoma mansoni RAR-like nuclear receptor 0.0066 0.0183 0.0346
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1494 0.5381 0.7662
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0281 0.0833
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.002 0.006
Brugia malayi Cytochrome P450 family protein 0.0025 0.0034 0.01
Echinococcus multilocularis lysine specific demethylase 5A 0.0164 0.0542 0.0542
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0175 0.0175
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0667 0.3024
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0083 0.0156
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0035 0.0231
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Brugia malayi MH1 domain containing protein 0.0025 0.0035 0.0104
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0431 0.1514 0.4493
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0015
Schistosoma mansoni nuclear receptor 0.0031 0.0057 0.0108
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0025 0.0025
Schistosoma mansoni caspase-7 (C14 family) 0.0062 0.017 0.0323
Leishmania major cathepsin L-like protease 0.0018 0.0009 0.0012
Echinococcus multilocularis geminin 0.0735 0.2618 0.2618
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0035 0.0035
Loa Loa (eye worm) thioredoxin reductase 0.0556 0.1969 0.5843
Mycobacterium ulcerans epimerase 0.0022 0.0026 0.007
Trichomonas vaginalis apoptosis inducing factor, putative 0.0114 0.0361 0.1634
Echinococcus granulosus GPCR family 2 0.0063 0.0175 0.0332
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0009 0.0012
Mycobacterium ulcerans monoxygenase 0.0114 0.0361 0.0983
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0114 0.0361 0.1071
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0273 0.094 0.1338
Echinococcus granulosus jumonji domain containing 1A 0.0044 0.0104 0.0196
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0338 0.0639
Brugia malayi CXXC zinc finger family protein 0.0061 0.0166 0.0493
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0114 0.0361 0.1798
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0065 0.0194
Trichomonas vaginalis esterase, putative 0.0038 0.0083 0.0371
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0012 0.0023
Schistosoma mansoni GMP synthetase 0.0035 0.007 0.0133
Onchocerca volvulus 0.0038 0.0083 0.022
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0066 0.0183 0.0542
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.0183 0.0542
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0025 0.0076
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0034 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0083 0.0117
Trypanosoma brucei metacaspase MCA2 0.0019 0.0012 0.0017
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0012 0.0036
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0009 0.0026
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0287 0.099 0.2937
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0231 0.0786 0.0786
Schistosoma mansoni agrin 0.008 0.0237 0.0448
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.0183 0.0542
Loa Loa (eye worm) RNA binding protein 0.0067 0.0188 0.0557
Brugia malayi beta-NAC-like protein 0.0037 0.0079 0.0233
Echinococcus granulosus ecdysone induced protein 78C 0.0066 0.0183 0.0346
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0083 0.0371
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.0183 0.0346
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Plasmodium falciparum metacaspase 1 0.0019 0.0012 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Loa Loa (eye worm) Smad1 0.0025 0.0035 0.0104
Trichomonas vaginalis abcb9, putative 0.0022 0.0025 0.0111
Brugia malayi nuclear hormone receptor 0.0031 0.0057 0.0168
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.002 0.0061
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0025 0.0076
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0189 0.0269
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.012 0.0227
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Schistosoma mansoni survival motor neuron protein 0.0054 0.014 0.0264
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0072 0.0207 0.0934
Loa Loa (eye worm) hypothetical protein 0.0043 0.01 0.0296
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0025 0.0111
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0374 0.1897
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0079 0.0319
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0114 0.0361 0.0514
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Echinococcus multilocularis serotonin receptor 0.0143 0.0466 0.0466
Schistosoma mansoni phosphatidylserine receptor 0.0044 0.0104 0.0196
Brugia malayi nuclear receptor RXR 0.0035 0.007 0.0208
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0118 0.0373 0.1106
Mycobacterium ulcerans glutamate synthase subunit beta 0.0114 0.0361 0.0983
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0057 0.0168
Trypanosoma cruzi NAD+ synthase, putative 0.0087 0.026 0.037
Loa Loa (eye worm) hepatopoietin HPO2 0.0038 0.0083 0.0247
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0062 0.0317
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0065 0.0093
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0114 0.0361 0.1559
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.0183 0.0542
Loa Loa (eye worm) hypothetical protein 0.0085 0.0255 0.0756
Trichomonas vaginalis glutamate synthase, putative 0.0114 0.0361 0.1634
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0065 0.0065
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0165 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0361 0.0514
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0189 0.0634 0.0634
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0062 0.0274
Echinococcus multilocularis cysteine protease 0.0018 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Echinococcus multilocularis neuropeptide s receptor 0.052 0.1836 0.1836
Schistosoma mansoni polycystin 1-related 0.0043 0.01 0.0189
Schistosoma mansoni nuclear receptor 0.0031 0.0057 0.0108
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.007 0.0209
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0431 0.1514 0.2867
Trypanosoma cruzi NAD+ synthase, putative 0.0087 0.026 0.037
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.008 0.0237 0.1202
Brugia malayi hypothetical protein 0.0043 0.0103 0.0304
Brugia malayi nuclear receptor NHR-88 0.0031 0.0057 0.0168
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0303 0.1049 0.6889
Echinococcus granulosus geminin 0.0735 0.2618 0.4957
Brugia malayi jmjC domain containing protein 0.0044 0.0104 0.0307
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.008 0.0237 0.1202
Echinococcus multilocularis muscleblind protein 0.0317 0.11 0.11
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Loa Loa (eye worm) hypothetical protein 0.0044 0.0104 0.0308
Schistosoma mansoni smad1 5 8 and 0.0025 0.0035 0.0067
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0273 0.094 0.1338
Echinococcus multilocularis cysteine protease 0.0018 0.0009 0.0009
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0025 0.0025
Brugia malayi beta-lactamase 0.0038 0.0083 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0035 0.005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0066 0.0183 0.0183
Echinococcus multilocularis GPCR, family 2 0.0063 0.0175 0.0175
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0188 0.0558
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0026 0.007
Leishmania major cathepsin L-like protease 0.0018 0.0009 0.0012
Brugia malayi hypothetical protein 0.0073 0.0211 0.0627
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0009 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0012 0.0019
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0025 0.0111
Loa Loa (eye worm) glutaminase 2 0.0288 0.0994 0.295
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0287 0.099 0.2937
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.0675 0.2002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Loa Loa (eye worm) intermediate filament protein 0.003 0.0054 0.0159
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0012 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.0675 0.2002
Plasmodium vivax thioredoxin reductase, putative 0.0556 0.1969 1
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0195 0.0655 0.3296
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.01 0.0189
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni smad1 5 8 and 0.0025 0.0035 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0079 0.0353
Schistosoma mansoni lamin 0.003 0.0054 0.0101
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0189 0.0269
Brugia malayi isocitrate dehydrogenase 0.0033 0.0065 0.0194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Loa Loa (eye worm) DR-78 0.0031 0.0057 0.0169
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0025 0.0025
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0084 0.0377
Brugia malayi ecdysteroid receptor 0.0066 0.0183 0.0542
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0001 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.002 0.0029
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0114 0.0361 0.0983
Echinococcus granulosus peregrin 0.0032 0.0062 0.0118
Schistosoma mansoni rab6-interacting 0.0043 0.01 0.0189
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0105
Echinococcus granulosus jun protein 0.0093 0.0284 0.0538
Brugia malayi Thioredoxin reductase 0.0556 0.1969 0.5843
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.012 0.0227
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0009 0.0009
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0035 0.0096
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0009 0.0009
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0083 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Echinococcus granulosus Smad4 0.0025 0.0035 0.0067
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0026 0.0169
Echinococcus multilocularis lysine specific demethylase 6a 0.0044 0.0104 0.0104
Schistosoma mansoni inositol monophosphatase 0.0041 0.0094 0.0178
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0057 0.0108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0168 0.0555 0.105
Loa Loa (eye worm) hypothetical protein 0.008 0.0237 0.0702
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0057 0.0108
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0195 0.0655 0.3326
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0026 0.0076
Trypanosoma brucei protein kinase, putative 0.0108 0.0338 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0079 0.0353
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0444 0.1316
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0066 0.0183 0.0542
Loa Loa (eye worm) doublecortin family protein 0.0043 0.01 0.0296
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0338 0.0641
Leishmania major hypothetical protein, conserved 0.0038 0.0083 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0107 0.0203
Echinococcus multilocularis Smad4 0.0025 0.0035 0.0035
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0083 0.0118
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0025 0.0111
Mycobacterium tuberculosis Conserved hypothetical protein 0.1024 0.3673 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0114 0.0361 0.1605
Brugia malayi Augmenter of liver regeneration 0.0038 0.0083 0.0246
Leishmania major cathepsin L-like protease 0.0067 0.0189 0.0269
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0087 0.026 0.1175
Onchocerca volvulus Putative organic anion transporter 0.0118 0.0373 0.1083
Echinococcus multilocularis thyroid hormone receptor alpha 0.0066 0.0183 0.0183
Echinococcus multilocularis multidrug resistance protein 1 0.0016 0.0001 0.0001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0094 0.0255
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0035 0.0104
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0114 0.0361 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Onchocerca volvulus 0.0118 0.0373 0.1083
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Brugia malayi hypothetical protein 0.0035 0.007 0.0208
Brugia malayi MH2 domain containing protein 0.0366 0.1277 0.379
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0166 0.0494
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Schistosoma mansoni jumonji domain containing protein 0.0209 0.0706 0.1337
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.0338 0.0639
Leishmania major hypothetical protein, conserved 0.0114 0.0361 0.0514
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Leishmania major cathepsin L-like protease 0.0067 0.0189 0.0269
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0037
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0047 0.0116 0.0116
Schistosoma mansoni organic anion transporter 0.0118 0.0373 0.0705
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0036
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1104 0.3961 0.564
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0079 0.0112
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.008 0.0237 0.0702
Schistosoma mansoni multidrug resistance protein 0.0022 0.0025 0.0048
Treponema pallidum NADH oxidase 0.0431 0.1514 0.6839
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Echinococcus multilocularis caspase 8 0.0019 0.0012 0.0012
Echinococcus granulosus microtubule associated protein 2 0.1466 0.5282 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0168 0.0555 0.1646
Loa Loa (eye worm) glutaminase 0.0288 0.0994 0.295
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0431 0.1514 0.9948
Mycobacterium ulcerans hypothetical protein 0.1024 0.3673 1
Echinococcus multilocularis neuropeptide receptor A26 0.052 0.1836 0.1836
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0087 0.026 0.1281
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.092 0.3295 0.4691
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0083 0.0371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0114 0.0361 0.0361
Schistosoma mansoni steroid hormone receptor ad4bp 0.0066 0.0183 0.0346
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.0338 0.1456
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0114 0.0361 0.0983
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0185
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0066 0.0183 0.0183
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0035 0.007 0.0315
Mycobacterium ulcerans hypothetical protein 0.0025 0.0035 0.0096
Brugia malayi MH1 domain containing protein 0.0025 0.0035 0.0104
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0057 0.0108
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0012 0.0012
Brugia malayi intermediate filament protein 0.003 0.0054 0.0158
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0338 0.0482
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0114 0.0361 0.0684
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0009 0.0009
Brugia malayi Cell death protein 3 precursor 0.0062 0.017 0.0505
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0009 0.0035
Trichomonas vaginalis glutathione reductase, putative 0.0431 0.1514 0.6867
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0035 0.0096
Schistosoma mansoni hypothetical protein 0.0137 0.0444 0.084
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0087 0.026 0.1319
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0118 0.0373 0.0373
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0057 0.0168
Mycobacterium ulcerans lipase LipD 0.0038 0.0083 0.0224
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0083 0.0423
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0026
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.002 0.002
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0175 0.052
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.01 0.01
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.008 0.0237 0.0702
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0828 0.2253
Schistosoma mansoni hypothetical protein 0.0735 0.2618 0.4957
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0012 0.0033
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0026 0.007
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0065 0.0124
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0057 0.0108
Brugia malayi photoreceptor-specific nuclear receptor 0.0066 0.0183 0.0542
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Mycobacterium ulcerans NADH dehydrogenase 0.0114 0.0361 0.0983
Plasmodium falciparum thioredoxin reductase 0.0556 0.1969 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0431 0.1514 0.2867
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.0675 0.2002
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.007 0.0208
Mycobacterium ulcerans hypothetical protein 0.0114 0.0361 0.0983
Schistosoma mansoni lozenge 0.0118 0.0374 0.0708
Toxoplasma gondii NADPH-glutathione reductase 0.0431 0.1514 0.769
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0114 0.0361 0.1833
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0039 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0009 0.0023
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0114 0.0361 0.2371
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.002 0.0055
Echinococcus granulosus lysine specific demethylase 5A 0.0168 0.0555 0.105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0066 0.0183 0.0543
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0083 0.0118
Trypanosoma brucei metacaspase 0.0019 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0188 0.0355
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.0338 0.0338
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.044 0.1545 0.4585
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0114 0.0361 0.1634
Schistosoma mansoni hypothetical protein 0.0074 0.0215 0.0407
Loa Loa (eye worm) hypothetical protein 0.0091 0.0275 0.0816
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0025 0.0075
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0104 0.0147
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0114 0.0361 0.0684
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.008 0.0237 0.1202
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0431 0.1514 0.4123
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0114 0.0361 0.1605
Trypanosoma cruzi trypanothione reductase, putative 0.0556 0.1969 0.2804
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0178 0.0178
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0114 0.0361 0.1798
Schistosoma mansoni loxhd1 0.0043 0.01 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0057 0.0108
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0433 0.1522 0.772
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0114 0.0361 0.0361
Schistosoma mansoni lamin 0.003 0.0054 0.0101
Schistosoma mansoni follistatin 0.008 0.0237 0.0448
Schistosoma mansoni thyroid hormone receptor 0.0066 0.0183 0.0346
Loa Loa (eye worm) hypothetical protein 0.0043 0.01 0.0296
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0114 0.0361 0.2268
Echinococcus multilocularis lamin 0.003 0.0054 0.0054
Entamoeba histolytica hypothetical protein 0.0074 0.0215 0.0938
Leishmania major NAD synthase, putative 0.0087 0.026 0.037
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0062 0.0118
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.01 0.0189
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0281 0.0281
Leishmania major cathepsin L-like protease 0.0018 0.0009 0.0012
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0188 0.0188
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0039 0.0106
Brugia malayi Pre-SET motif family protein 0.044 0.1545 0.4585
Echinococcus granulosus RUN 0.0043 0.01 0.0189
Onchocerca volvulus 0.0031 0.0057 0.0144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0012 0.0023
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0941 0.337 1
Schistosoma mansoni hypothetical protein 0.0063 0.0175 0.0332
Brugia malayi Doublecortin family protein 0.0043 0.01 0.0296
Toxoplasma gondii cathepsin CPL 0.0018 0.0009 0.0044
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0087 0.026 0.0707
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0012 0.0019
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.0338 0.0482
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0114 0.0361 0.0514
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0114 0.0361 0.1071
Brugia malayi GMP synthase 0.0035 0.007 0.0209
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0178 0.0905
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0108 0.0338 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Brugia malayi bZIP transcription factor family protein 0.0093 0.0284 0.0843
Schistosoma mansoni phd/f-box containing protein 0.0044 0.0104 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0057 0.0108
Mycobacterium ulcerans NAD synthetase 0.0087 0.026 0.0707
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0035 0.007 0.0209
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0083 0.0224
Echinococcus multilocularis expressed protein 0.008 0.0237 0.0237
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0025 0.0025
Echinococcus granulosus cpg binding protein 0.0064 0.0179 0.0339
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0433 0.1522 1
Onchocerca volvulus 0.0501 0.1766 0.5229
Loa Loa (eye worm) MH2 domain-containing protein 0.0366 0.1277 0.3791
Loa Loa (eye worm) hypothetical protein 0.008 0.0237 0.0702
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.0166
Schistosoma mansoni hypothetical protein 0.0869 0.3108 0.5884
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0059 0.0175
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0137 0.0195
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0361 0.2371
Echinococcus granulosus caspase 2 0.0062 0.017 0.0323
Brugia malayi conserved hypotetical protein 0.0031 0.0057 0.0168
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0073 0.0218
Schistosoma mansoni smad 0.0025 0.0035 0.0067
Brugia malayi hypothetical protein 0.0027 0.0041 0.0122
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1104 0.3961 0.564
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Leishmania major cathepsin L-like protease 0.0018 0.0009 0.0012
Schistosoma mansoni chromobox protein 0.0077 0.0226 0.0429
Schistosoma mansoni lipoxygenase 0.0189 0.0634 0.12
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0094 0.0277
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0168 0.0239
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0057 0.0169
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0066 0.0183 0.0346
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0066 0.0183 0.0346
Loa Loa (eye worm) glutathione reductase 0.0556 0.1969 0.5843
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0083 0.0371
Leishmania major hypothetical protein, conserved 0.0044 0.0104 0.0147
Plasmodium falciparum ferrodoxin reductase-like protein 0.0114 0.0361 0.1798
Schistosoma mansoni coup transcription factor 0.0066 0.0183 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0066 0.0183 0.0542
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.0338 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Loa Loa (eye worm) hypothetical protein 0.008 0.0237 0.0702
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0102 0.0279
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0065 0.0124
Brugia malayi hypothetical protein 0.0035 0.007 0.0208
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.092 0.3295 0.4691
Echinococcus multilocularis dnaJ subfamily B 0.0869 0.3108 0.3108
Mycobacterium ulcerans glutaminase 0.0288 0.0994 0.2706
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0009 0.0035
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0041 0.0166
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Trypanosoma cruzi metacaspase, putative 0.0019 0.0012 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0066 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Loa Loa (eye worm) hypothetical protein 0.008 0.0237 0.0702
Loa Loa (eye worm) agrin synaptic family protein 0.008 0.0237 0.0702
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0057 0.0108
Brugia malayi sodium-independent organic anion transporter family protein 0.0118 0.0373 0.1105
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0195 0.0655 0.4302
Brugia malayi nuclear hormone receptor 0.0066 0.0183 0.0542
Trypanosoma brucei NADH dehydrogenase 0.0114 0.0361 0.0514
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0034 0.0048
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0556 0.1969 0.5361
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0025 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0178 0.0337
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0025 0.0085
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.01 0.0465
Trypanosoma cruzi MFS transporter, putative 0.0118 0.0373 0.053
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0066 0.0183 0.0346
Loa Loa (eye worm) hypothetical protein 0.0201 0.0675 0.2002
Schistosoma mansoni glutamate synthase 0.0114 0.0361 0.0684
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0114 0.0361 0.0514
Loa Loa (eye worm) hypothetical protein 0.0941 0.337 1
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0035 0.0104
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0114 0.0361 0.0983
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0114 0.0361 0.2371
Leishmania major cathepsin L-like protease 0.0018 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0063 0.0175 0.0332
Echinococcus granulosus Solute carrier organic anion transporter family 0.0118 0.0373 0.0705
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0057 0.0169
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0621 0.2205 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0114 0.0361 0.1798
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0066 0.0183 0.0542
Schistosoma mansoni hypothetical protein 0.0103 0.0319 0.0604
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0114 0.0361 0.0684
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Leishmania major hypothetical protein, conserved 0.0038 0.0083 0.0117
Brugia malayi nuclear receptor NHR-88 0.0066 0.0183 0.0542
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0025 0.0076
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.0338 0.0641
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0188 0.0355
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0273 0.094 0.1338
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0047 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0361 0.0514
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0038 0.0083 0.0083
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0114 0.0361 0.0514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Echinococcus multilocularis RUN 0.0043 0.01 0.01
Echinococcus granulosus retinoic acid receptor rxr beta a 0.017 0.0562 0.1063
Brugia malayi nuclear receptor RXR 0.0031 0.0057 0.0168
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0083 0.0224
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0431 0.1514 0.4123
Echinococcus granulosus lamin dm0 0.003 0.0054 0.0101
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0087 0.026 0.1705
Brugia malayi hypothetical protein 0.0074 0.0215 0.0637
Brugia malayi Cathepsin L-like precursor 0.0018 0.0009 0.0025
Leishmania major p-glycoprotein 0.0022 0.0025 0.0036
Brugia malayi jmjC domain containing protein 0.0231 0.0786 0.2331
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0094 0.0133
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0065 0.0333
Leishmania major trypanothione reductase 0.0556 0.1969 0.2804
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0188 0.0355
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0066 0.0183 0.0543
Echinococcus granulosus tar DNA binding protein 0.0067 0.0188 0.0355
Echinococcus multilocularis cpg binding protein 0.0064 0.0179 0.0179
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0667 0.3024
Trichomonas vaginalis hypothetical protein 0.0195 0.0655 0.2968
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0062 0.0062
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0039 0.0085
Onchocerca volvulus 0.0073 0.0211 0.0603
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0065 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0114 0.0361 0.2371
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0065 0.0065
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0108 0.0338 0.0639
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0094 0.0133
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0021 0.0064
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0175 0.0521
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0361 0.0983
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0083 0.0118
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0038 0.0083 0.0158
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0012 0.0062
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0175 0.052
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0094 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0077 0.0224 0.0425
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0044 0.0104 0.0196
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0078 0.0212
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0065 0.0178
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0012 0.0062
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0039 0.0055
Echinococcus multilocularis FTZ F1 alpha 0.0066 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0025 0.0048
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0003 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0035 0.0096
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0035 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0025 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0107 0.0203
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0003 0.0009
Echinococcus granulosus FTZ F1 alpha 0.0066 0.0183 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0025 0.0111
Toxoplasma gondii melibiase subfamily protein 0.0108 0.0338 0.1715
Loa Loa (eye worm) hypothetical protein 0.0092 0.0281 0.0834
Schistosoma mansoni intermediate filament proteins 0.003 0.0054 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.0183 0.0542
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0024 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0066 0.0183 0.0346
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0195 0.0655 0.4225
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0057 0.0168
Mycobacterium tuberculosis Probable reductase 0.0114 0.0361 0.0983
Giardia lamblia Thioredoxin reductase 0.0114 0.0361 0.1559
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0035 0.0096
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0094 0.0477
Onchocerca volvulus 0.0025 0.0035 0.008
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0034 0.01
Brugia malayi Cytochrome P450 family protein 0.0025 0.0034 0.01
Treponema pallidum fructose-bisphosphate aldolase 0.0621 0.2205 1
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0087 0.026 0.0492
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Echinococcus multilocularis ecdysone induced protein 78C 0.0066 0.0183 0.0183
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0361 0.0983
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0079 0.0112
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0012 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0189 0.0269
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0103 0.0103
Plasmodium falciparum JmjC domain-containing protein, putative 0.0044 0.0104 0.0485
Plasmodium vivax GMP synthetase, putative 0.0035 0.007 0.0315
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0035 0.007 0.0358
Schistosoma mansoni jun-related protein 0.0076 0.0221 0.0418
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0114 0.0361 0.0361
Schistosoma mansoni jumonji domain containing protein 0.0044 0.0104 0.0196
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0025 0.0111
Echinococcus multilocularis peregrin 0.0032 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0245
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0066 0.0183 0.0346
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0114 0.0515
Brugia malayi hypothetical protein 0.0941 0.337 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0047 0.0116 0.022
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0079 0.0399
Echinococcus multilocularis survival motor neuron protein 1 0.0263 0.0902 0.0902
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.00000051216 0.00000096966
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.012 0.0227
Echinococcus multilocularis caspase 0.0019 0.0012 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.1466 0.5282 0.5282
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0056 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0041 0.0181
Loa Loa (eye worm) hypothetical protein 0.0114 0.0361 0.1071
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0273 0.094 0.1338
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0035 0.007 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0065 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0178 0.0337
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0025 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0079 0.0353
Trichomonas vaginalis abcb9, putative 0.0022 0.0025 0.0111
Leishmania major mitochondrial DNA polymerase beta 0.1945 0.7023 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0104 0.0308
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0085 0.0255 0.0693
Onchocerca volvulus 0.003 0.0054 0.0134
Brugia malayi glutamate synthase 0.0114 0.0361 0.1071
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0066 0.0183 0.0346
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0431 0.1514 0.1514
Brugia malayi secreted modular calcium-binding protein 1 0.008 0.0237 0.0702
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.008 0.0237 0.1202
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0009 0.0023
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0114 0.0315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.012 0.0227
Onchocerca volvulus 0.003 0.0054 0.0134
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0104 0.0147
Loa Loa (eye worm) hypothetical protein 0.0317 0.11 0.3263
Onchocerca volvulus 0.0034 0.0068 0.0177
Onchocerca volvulus 0.0118 0.0373 0.1083
Leishmania major basic transcription factor 3a, putative 0.0037 0.0079 0.0112
Leishmania major cathepsin L-like protease 0.0067 0.0189 0.0269
Brugia malayi ecdysone receptor 0.0031 0.0057 0.0168
Schistosoma mansoni hypothetical protein 0.0063 0.0175 0.0332
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0009 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0094 0.0094
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0094 0.0133
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0035 0.0067
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0114 0.0361 0.2371
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0035 0.0104
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0083 0.0156
Echinococcus multilocularis lamin dm0 0.003 0.0054 0.0054
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0094 0.0388
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0057 0.0144
Schistosoma mansoni cpg binding protein 0.0064 0.0179 0.0339
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0118 0.0373 0.0373
Brugia malayi nuclear receptor NHR-67 0.0031 0.0057 0.0168
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0795
Onchocerca volvulus Protein ultraspiracle homolog 0.0066 0.0183 0.0519
Loa Loa (eye worm) hypothetical protein 0.0118 0.0373 0.1106
Brugia malayi Steroid receptor seven-up type 2 0.0066 0.0183 0.0542
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0084 0.0377
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0035 0.0122
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.01 0.0189
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0188 0.0557
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0083 0.0371
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0114 0.0361 0.0983
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.002 0.0054
Brugia malayi beta-lactamase family protein 0.0038 0.0083 0.0245
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0317 0.1098 0.3256
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0303 0.1049 0.2855
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0021 0.0041
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.0338 0.0482
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0169
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0093 0.0284 0.0284
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0114 0.0361 0.0983
Schistosoma mansoni multidrug resistance protein 0.0022 0.0025 0.0048
Leishmania major hypothetical protein, conserved 0.0027 0.0041 0.0058
Trichomonas vaginalis set domain proteins, putative 0.05 0.1766 0.8008
Schistosoma mansoni rab6-interacting 0.0043 0.01 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni transcription factor btf3 0.0037 0.0079 0.0149
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0361 0.0983
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.002 0.0055
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0066 0.0183 0.0519
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0075
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0114 0.0361 0.1833
Brugia malayi hypothetical protein 0.0031 0.0057 0.0168
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0431 0.1514 0.4123
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0431 0.1514 0.9948
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0035 0.005
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0025 0.0076
Echinococcus multilocularis thioredoxin glutathione reductase 0.0556 0.1969 0.1969
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0114 0.0361 0.0514
Brugia malayi Melibiase family protein 0.0072 0.0207 0.0613
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0025 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0035 0.0096
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0085 0.0255 0.1672
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0195 0.0655 0.4256
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0066 0.0183 0.0542
Brugia malayi Heterochromatin protein 1 0.0077 0.0226 0.0671
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0114 0.0361 0.0361
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1945 0.7023 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0094 0.0278
Brugia malayi jmjC domain containing protein 0.0168 0.0555 0.1646
Echinococcus multilocularis transcription factor btf3 0.0037 0.0079 0.0079
Onchocerca volvulus 0.0114 0.0361 0.1048
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.01 0.0465
Onchocerca volvulus 0.0043 0.01 0.0271
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.002 0.0089
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0057 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Plasmodium falciparum thioredoxin reductase 0.0431 0.1514 0.768
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0361 0.0983
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0012 0.0023
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0062 0.0118
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0044 0.0104 0.0527
Schistosoma mansoni biogenic amine (5HT) receptor 0.0143 0.0466 0.0883
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0114 0.0361 0.0684
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0025 0.0129
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0195 0.0655 0.1783
Schistosoma mansoni nuclear hormone receptor 0.0066 0.0183 0.0346
Brugia malayi sodium-independent organic anion transporter family protein 0.0118 0.0373 0.1105
Schistosoma mansoni inositol monophosphatase 0.0041 0.0094 0.0178
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0078 0.0513
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0431 0.1514 0.4123
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0035 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1104 0.3961 0.564
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0066 0.0183 0.0543
Plasmodium vivax SET domain protein, putative 0.0064 0.0178 0.0865
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0079 0.0233
Plasmodium falciparum enoyl-acyl carrier reductase 0.0195 0.0655 0.3296
Onchocerca volvulus 0.0118 0.0373 0.1083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0178 0.0337
Plasmodium falciparum metacaspase-like protein 0.0019 0.0012 0.0019
Brugia malayi jmjC domain containing protein 0.0044 0.0104 0.0307
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0094 0.0177
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0025 0.0076
Brugia malayi jmjC domain containing protein 0.0044 0.0104 0.0307
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0114 0.0361 0.1605
Schistosoma mansoni hypothetical protein 0.0063 0.0175 0.0332
Schistosoma mansoni glutamate synthase 0.0114 0.0361 0.0684
Loa Loa (eye worm) transcription factor SMAD2 0.0366 0.1277 0.3791
Plasmodium falciparum glutathione reductase 0.0556 0.1969 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0035 0.0122
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.0338 0.0641
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0094 0.0422
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0114 0.0361 0.1071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0103 0.0304
Entamoeba histolytica hypothetical protein 0.0026 0.0039 0.0138
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0083 0.0245
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0009 0.0016
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0281 0.0532
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0114 0.0361 0.0983
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0338 0.1532
Schistosoma mansoni hypothetical protein 0.0043 0.0103 0.0194
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0057 0.0108
Entamoeba histolytica NAD synthetase, putative 0.0087 0.026 0.1143
Echinococcus multilocularis musashi 0.003 0.0054 0.0054
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0114 0.0361 0.1634
Brugia malayi sodium-independent organic anion transporter family protein 0.0118 0.0373 0.1105
Brugia malayi CHD4 protein 0.0016 0.0003 0.0009
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0114 0.0361 0.2268
Plasmodium vivax ferrodoxin reductase, putative 0.0114 0.0361 0.1798
Brugia malayi Inositol-1 0.0041 0.0094 0.0278
Echinococcus granulosus caspase 8 0.0019 0.0012 0.0023
Entamoeba histolytica hypothetical protein 0.0074 0.0215 0.0938
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0114 0.0361 0.2268
Schistosoma mansoni Smad4 0.0025 0.0035 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0014 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.012 0.0227
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0035 0.0096
Trypanosoma cruzi metacaspase, putative 0.0019 0.0012 0.0017
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0114 0.0361 0.0983
Treponema pallidum oxidoreductase 0.0114 0.0361 0.1559
Brugia malayi hypothetical protein 0.0118 0.0373 0.1105
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0035 0.0035
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0041 0.0209
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0114 0.0361 0.0514
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.063 0.2856
Schistosoma mansoni microtubule-associated protein tau 0.1466 0.5282 1
Plasmodium falciparum phd finger protein, putative 0.0032 0.0062 0.0274
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0431 0.1514 0.2156
Brugia malayi glutaminase DH11.1 0.0288 0.0994 0.2949
Brugia malayi Nuclear hormone receptor-like 1 0.0066 0.0183 0.0542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0009 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni ap endonuclease 0.0021 0.002 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0114 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0102 0.0461
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0431 0.1514 0.2156
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0195 0.0655 0.1783
Onchocerca volvulus 0.008 0.0237 0.0679
Loa Loa (eye worm) fibroinase 0.0018 0.0009 0.0026
Onchocerca volvulus 0.0066 0.0183 0.0519
Echinococcus multilocularis chromobox protein 1 0.0077 0.0226 0.0226
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0022 0.0025 0.0086
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0034 0.01
Schistosoma mansoni hypothetical protein 0.0032 0.0062 0.0118
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0083 0.0224
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0114 0.0361 0.1071
Loa Loa (eye worm) hypothetical protein 0.0066 0.0183 0.0543
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0109 0.0109
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0058
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.014 0.0414
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0065 0.0194
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0072
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0034 0.0092
Echinococcus granulosus phd:f box containing protein 0.0044 0.0104 0.0196
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0039 0.0255
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0025 0.0129
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0178 0.0178
Onchocerca volvulus 0.0038 0.0083 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Echinococcus multilocularis phd:f box containing protein 0.0044 0.0104 0.0104
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0044 0.0104 0.0147
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0215 0.0407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0066 0.0183 0.0543
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0009 0.0009
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0003 0.0006
Schistosoma mansoni ap endonuclease 0.0021 0.002 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.0183 0.0542
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.092 0.3295 0.4691
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0025 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1494 0.5381 0.7662
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0114 0.0361 0.0514
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0083 0.0117
Schistosoma mansoni disulfide oxidoreductase 0.0114 0.0361 0.0684
Loa Loa (eye worm) beta-lactamase 0.0038 0.0083 0.0245
Brugia malayi hypothetical protein 0.0031 0.0057 0.0168
Mycobacterium ulcerans GMP synthase 0.0035 0.007 0.0191
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0018 0.0076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0333 0.1157 0.1648
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0003 0.0006
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0065 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0178 0.0337
Schistosoma mansoni protein phosphatase 2C 0.0044 0.0104 0.0196
Loa Loa (eye worm) hypothetical protein 0.0143 0.0466 0.1383
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0108 0.0338 0.0338
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0094 0.0178
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0338 0.1532
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0035 0.007 0.0133
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0114 0.0361 0.1798
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0025 0.0111
Schistosoma mansoni cpg binding protein 0.0064 0.0179 0.0339
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0066 0.0183 0.0346
Schistosoma mansoni multidrug resistance protein 0.0022 0.0025 0.0048
Trypanosoma brucei trypanothione reductase 0.0556 0.1969 0.2804
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0025 0.0111
Brugia malayi hypothetical protein 0.0263 0.0902 0.2675
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0057 0.0168
Toxoplasma gondii protease inhibitor PI2 0.008 0.0237 0.1202
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0159
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.0338 0.0338
Echinococcus multilocularis agrin 0.008 0.0237 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Toxoplasma gondii thioredoxin reductase 0.0556 0.1969 1
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0114 0.0361 0.0983
Mycobacterium leprae Probable lipase LipE 0.0038 0.0083 0.0542
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0094 0.0422
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0065 0.0333
Echinococcus granulosus transcription factor btf3 0.0037 0.0079 0.0149
Plasmodium vivax JmjC domain containing protein 0.0044 0.0104 0.0485
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0025 0.0036
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.007 0.0133
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0012 0.0052
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0114 0.0361 0.0514
Schistosoma mansoni hypothetical protein 0.0076 0.0221 0.0418
Onchocerca volvulus Cell death protein 3 homolog 0.0062 0.017 0.0481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0189 0.0269
Echinococcus granulosus smad 0.0025 0.0035 0.0067
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0135 0.0435 0.0435
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0057 0.0168
Loa Loa (eye worm) hypothetical protein 0.0072 0.0207 0.0613
Echinococcus multilocularis serotonin receptor 0.0143 0.0466 0.0466
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0009 0.0035
Plasmodium vivax metacaspase 1, putative 0.0019 0.0012 0.0019
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0083 0.0224
Brugia malayi RNA binding protein 0.0067 0.0188 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.0035
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0215 0.0407
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.012 0.0356
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0012 0.0062
Schistosoma mansoni glutamate synthase 0.0114 0.0361 0.0684
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0009 0.0025
Mycobacterium ulcerans hypothetical protein 0.0022 0.0026 0.007
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0175 0.0175
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0303 0.1049 0.2855
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0025 0.0068
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0189 0.0634 0.12
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0025 0.0111
Schistosoma mansoni sulfide quinone reductase 0.0114 0.0361 0.0684
Echinococcus granulosus agrin 0.008 0.0237 0.0448
Schistosoma mansoni hypothetical protein 0.0114 0.0361 0.0684
Toxoplasma gondii endonuclease IV APN 0.0085 0.0255 0.1293
Echinococcus granulosus muscleblind protein 0.0317 0.11 0.2082
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0114 0.0361 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Brugia malayi Muscleblind-like protein 0.0317 0.11 0.3263
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.012 0.012
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0114 0.0361 0.1605
Echinococcus multilocularis caspase 2 0.0062 0.017 0.017
Brugia malayi hypothetical protein 0.0017 0.0007 0.002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0025 0.0025
Echinococcus multilocularis JmjC domain containing protein 4 0.0044 0.0104 0.0104
Toxoplasma gondii transporter, major facilitator family protein 0.0118 0.0373 0.1892
Onchocerca volvulus Alhambra homolog 0.0032 0.0062 0.016
Loa Loa (eye worm) programmed cell death 8 0.0114 0.0361 0.1071
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0083 0.0423
Brugia malayi beta-lactamase family protein 0.0038 0.0083 0.0245
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0066 0.0183 0.0183
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0035 0.0231
Plasmodium falciparum glutathione reductase 0.0431 0.1514 0.768
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0083 0.0245
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0114 0.0361 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0188 0.0355
Brugia malayi multidrug resistance protein 3 0.0022 0.0025 0.0075
Brugia malayi glutathione reductase 0.0556 0.1969 0.5843
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0433 0.1522 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0114 0.0361 0.1833
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0118 0.0373 0.0705
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.002 0.0029
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0035 0.0067
Trichomonas vaginalis mercuric reductase, putative 0.0431 0.1514 0.6867
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0431 0.1514 0.4123
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0066 0.0183 0.0542
Brugia malayi steroid hormone receptor 0.0066 0.0183 0.0542
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0114 0.0361 0.1634
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.0338 0.1719
Mycobacterium ulcerans hypothetical protein 0.0038 0.0083 0.0224
Echinococcus granulosus neuropeptide receptor A26 0.052 0.1836 0.3476
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0083 0.0224
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0433 0.1522 0.4144
Trypanosoma brucei hypothetical protein, conserved 0.0114 0.0361 0.0514
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0621 0.2205 1
Onchocerca volvulus 0.0022 0.0025 0.005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0175 0.0332
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0178 0.0529
Echinococcus granulosus lysine specific demethylase 6a 0.0044 0.0104 0.0196
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.099 0.4488
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0065 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0035 0.005
Entamoeba histolytica hypothetical protein 0.0037 0.0079 0.0319
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0105
Loa Loa (eye worm) hypothetical protein 0.0263 0.0902 0.2676
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.0043 0.0102 0.0304
Brugia malayi chromobox protein homolog 3 0.0043 0.0102 0.0304
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0066 0.0183 0.0346
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0114 0.0361 0.0983
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0009 0.0016
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0039 0.0155
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0219
Echinococcus granulosus thioredoxin glutathione reductase 0.0556 0.1969 0.3728
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0065 0.0093
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0431 0.1514 0.4123
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0188 0.0556
Entamoeba histolytica hypothetical protein 0.0074 0.0215 0.0938
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0025 0.0111

Activities

Activity type Activity value Assay description Source Reference
BP (functional) = -13 mmHg Antihypertensive activity in renal hypertensive rats 6 hr after oral administration (10 mg/Kg) ChEMBL. 7097726
BP (functional) = -10 mmHg Antihypertensive activity in renal hypertensive rats 4 hr after oral administration (10 mg/Kg) ChEMBL. 7097726
BP (functional) = -10 mmHg Change in blood pressure in normotensive anesthetized cat. ChEMBL. 7097726
BP (functional) = -8 mmHg Antihypertensive activity in renal hypertensive rats 2 hr after oral administration (10 mg/Kg) ChEMBL. 7097726
BP (functional) = -8 mmHg Antihypertensive activity in renal hypertensive rats 8 hr after oral administration (10 mg/Kg) ChEMBL. 7097726
BP (functional) = -6 mmHg Antihypertensive activity in renal hypertensive rats 1 hr after oral administration (10 mg/Kg) ChEMBL. 7097726
BP (functional) = 153 mmHg Decrease in blood pressure in normotensive anesthetized cat at dose 10 mg/Kg iv ChEMBL. 7097726

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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