Detailed information for compound 290806

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.695 | Formula: C28H49NO
  • H donors: 2 H acceptors: 1 LogP: 6.62 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCC[C@H](C1CCN[C@@]2([C@]1(C)CCC1=C2CCC2[C@]1(C)CC[C@@H](C2)O)C)C)C
  • InChi: 1S/C28H49NO/c1-19(2)8-7-9-20(3)23-14-17-29-28(6)25-11-10-21-18-22(30)12-15-26(21,4)24(25)13-16-27(23,28)5/h19-23,29-30H,7-18H2,1-6H3/t20-,21?,22+,23?,26+,27-,28+/m1/s1
  • InChiKey: FXYWZSZQPOXFIV-HVJFXDQJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0024 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0022 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0024 0.0024
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Loa Loa (eye worm) ACC-1 protein 0.002 0.004 0.004
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0021 0.0043 0.0078
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0031 0.0077 0.0076
Leishmania major cathepsin L-like protease 0.0025 0.0058 0.0041
Trypanosoma brucei protein kinase, putative 0.0029 0.0071 0.0068
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0022 0.0022
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.1629 0.5572 0.5572
Echinococcus granulosus glycine receptor subunit beta 0.002 0.004 0.0072
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0202 0.0201
Brugia malayi isocitrate dehydrogenase 0.0021 0.0042 0.0042
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.004 0.004
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.008 0.0144
Toxoplasma gondii FATC domain-containing protein 0.0021 0.0043 0.004
Schistosoma mansoni tyrosine kinase 0.0079 0.0242 0.0434
Schistosoma mansoni glutaminase 0.0132 0.0424 0.0761
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.004 0.0072
Echinococcus granulosus polycomb protein SCMH1 0.0023 0.0048 0.0086
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.003 0.0075 0.0075
Brugia malayi Bromodomain containing protein 0.0018 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0092 0.0286 0.0281
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0202 0.0353
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Echinococcus granulosus lamin dm0 0.0012 0.0011 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0547 0.1852 0.3323
Onchocerca volvulus 0.0032 0.008 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0017
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Echinococcus multilocularis neuropeptide receptor A26 0.0437 0.1474 0.2645
Echinococcus multilocularis GPCR, family 2 0.0042 0.0114 0.0205
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0024 0.002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0022 0.004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0014 0.0017 0.0095
Loa Loa (eye worm) acetylcholine receptor protein 0.0009 0.0002 0.0002
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0088 0.0157
Toxoplasma gondii target of rapamycin (TOR), putative 0.0015 0.0024 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Onchocerca volvulus 0.0009 0.0002 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0043 0.0043
Schistosoma mansoni zinc finger protein 0.0011 0.0009 0.0016
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.1629 0.5572 0.5572
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0079 0.0242 0.0242
Leishmania major hypothetical protein, conserved 0.0067 0.0202 0.0185
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0031 0.0077 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.1629 0.5572 0.5572
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.004 0.0072
Echinococcus granulosus beta LACTamase domain containing family member 0.0067 0.0202 0.0362
Entamoeba histolytica phosphofructokinase, putative 0.0046 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0092 0.0286 0.1957
Echinococcus granulosus peroxidasin 0.0027 0.0063 0.0114
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Onchocerca volvulus Chorion peroxidase homolog 0.0027 0.0063 0.0114
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0011 0.0008 0.0008
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0022 0.0022
Mycobacterium ulcerans 6-phosphofructokinase 0.0046 0.013 0.0125
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0088 0.0083
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1629 0.5572 1
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0202 0.0201
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0097 0.0096
Echinococcus granulosus SAM and MBT domain containing protein 0.0023 0.0048 0.0086
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0075 0.0228 0.0409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0022 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi mbt repeat family protein 0.0023 0.0048 0.0048
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.004 0.0072
Giardia lamblia GTOR 0.0015 0.0024 0.0018
Mycobacterium tuberculosis Probable esterase LipL 0.0067 0.0202 0.1372
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0021 0.0042 0.0042
Mycobacterium ulcerans esterase/lipase LipP 0.0067 0.0202 0.0197
Brugia malayi Protein kinase domain containing protein 0.0048 0.0134 0.0134
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0046 0.013 0.0874
Loa Loa (eye worm) nuclear factor I 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0046
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0088 0.0088
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0025 0.0055 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.008 0.008
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0022 0.004
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0034 0.0088 0.0157
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.2917 1 1
Schistosoma mansoni acetylcholine receptor subunit beta 0.0009 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.1629 0.5572 0.5572
Brugia malayi Cation transporter family protein 0.002 0.004 0.004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.001 0.0005 0.0013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.003 0.0074 0.0132
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Schistosoma mansoni ferritin 0.0016 0.0026 0.0047
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.004 0.0072
Brugia malayi Peroxidasin 0.0027 0.0063 0.0063
Entamoeba histolytica hypothetical protein 0.005 0.0143 0.0142
Brugia malayi 6-phosphofructokinase 0.0046 0.013 0.013
Echinococcus granulosus neuropeptide receptor A26 0.0437 0.1474 0.2645
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis serine protein kinase ATM 0.0021 0.0043 0.0078
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0024 0.002
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.008 0.0144
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Onchocerca volvulus Dual oxidase homolog 0.0027 0.0063 0.0114
Brugia malayi nuclear receptor NHR-67 0.0015 0.0022 0.0022
Schistosoma mansoni cpg binding protein 0.0037 0.0097 0.0174
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0011 0.002
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0063 0.0063
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.008 0.008
Plasmodium vivax ataxin-2 like protein, putative 0.0033 0.0085 0.0144
Schistosoma mansoni hypothetical protein 0.0145 0.0469 0.0841
Echinococcus multilocularis transcription factor Dp 1 0.0018 0.0032 0.0057
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0022 0.004
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0029 0.0071 0.0054
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.008 0.0245 0.044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Echinococcus multilocularis microtubule associated protein 2 0.1602 0.5479 0.9831
Entamoeba histolytica hypothetical protein 0.005 0.0143 0.0142
Leishmania major cathepsin L-like protease 0.0025 0.0058 0.0041
Onchocerca volvulus 0.0067 0.0202 0.0362
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0042 0.0114 0.0205
Echinococcus multilocularis mitogen activated protein kinase 0.0029 0.0071 0.0128
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0022 0.004
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0011 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0011
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0031 0.0077 0.0073
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0202 0.0201
Echinococcus granulosus histone acetyltransferase MYST2 0.0026 0.0059 0.0106
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.005
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0097 0.0164
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.1629 0.5572 0.5571
Schistosoma mansoni microtubule-associated protein tau 0.1602 0.5479 0.9831
Brugia malayi RNA recognition motif domain containing protein 0.0113 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.2917 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0202 0.0362
Onchocerca volvulus 0.0107 0.0337 0.0604
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.008 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0046 0.013 0.0129
Loa Loa (eye worm) ACC-1 protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Mycobacterium ulcerans glutaminase 0.0132 0.0424 0.0419
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0024 0.0024
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.008 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.005 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.008 0.008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.008 0.0144
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0037 0.0066
Brugia malayi nuclear receptor NHR-88 0.0015 0.0022 0.0022
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0017
Mycobacterium ulcerans beta-lactamase 0.0067 0.0202 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0016 0.0026 0.0159
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0011 0.002
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0029 0.0071 0.0071
Brugia malayi MH2 domain containing protein 0.0284 0.0948 0.0948
Mycobacterium leprae Probable lipase LipE 0.0067 0.0202 0.2458
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0202 0.0201
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0026 0.0059 0.0106
Schistosoma mansoni synaptic glycoprotein sc2 related 0.1629 0.5572 1
Brugia malayi Synaptic glycoprotein SC2 0.1629 0.5572 0.5572
Trypanosoma brucei hypothetical protein, conserved 0.0067 0.0202 0.0198
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Onchocerca volvulus 0.0067 0.0202 0.0362
Onchocerca volvulus 0.0015 0.0022 0.004
Schistosoma mansoni coup transcription factor 0.0032 0.008 0.0144
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0575 0.1947 0.3494
Trichomonas vaginalis phosphofructokinase, putative 0.0046 0.013 0.0129
Onchocerca volvulus 0.0067 0.0202 0.0362
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.0174 0.057 0.1023
Trypanosoma cruzi cruzipain precursor, putative 0.0025 0.0058 0.0057
Echinococcus granulosus expressed protein 0.0016 0.0026 0.0047
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.1629 0.5572 0.5571
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0097 0.0093
Schistosoma mansoni tyrosine kinase 0.0048 0.0134 0.024
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.004 0.0072
Brugia malayi hypothetical protein 0.0015 0.0022 0.0022
Echinococcus multilocularis SAM and MBT domain containing protein 0.0023 0.0048 0.0086
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0043 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0017 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.008 0.008
Loa Loa (eye worm) DR-78 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0085 0.0144
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0046 0.013 0.15
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.004 0.004
Schistosoma mansoni ferritin light chain 0.0016 0.0026 0.0047
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0025 0.0055 0.0054
Echinococcus granulosus synaptic glycoprotein sc2 0.1629 0.5572 1
Echinococcus multilocularis lamin 0.0012 0.0011 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.008 0.0144
Schistosoma mansoni neurotransmitter gated ion channel 0.0011 0.0008 0.0014
Trichomonas vaginalis glutaminase, putative 0.0132 0.0424 0.0424
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.004 0.0072
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0134 0.0134
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.004 0.0072
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.0246 0.0441
Schistosoma mansoni lamin 0.0012 0.0011 0.002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.008 0.0144
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.004 0.004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0042 0.0042
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0063 0.0063
Echinococcus granulosus mitogen activated protein kinase 0.0029 0.0071 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.008 0.008
Schistosoma mansoni ferritin 0.0016 0.0026 0.0047
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0016 0.0026 0.0159
Echinococcus granulosus microtubule associated protein 2 0.1602 0.5479 0.9831
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0088 0.0157
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0014 0.0017 0.0012
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.1629 0.5572 0.5572
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0022 0.0022
Loa Loa (eye worm) RNA binding protein 0.0113 0.036 0.036
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0113 0.036 0.036
Trichomonas vaginalis esterase, putative 0.0067 0.0202 0.0201
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0022 0.0039
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.004 0.004
Brugia malayi Pre-SET motif family protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0042 0.0114 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.008 0.008
Brugia malayi latrophilin 2 splice variant baaae 0.009 0.0281 0.0281
Echinococcus multilocularis histone acetyltransferase MYST2 0.0026 0.0059 0.0106
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0031 0.0077 0.0077
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0029 0.0071 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.008 0.008
Schistosoma mansoni tyrosine kinase 0.008 0.0245 0.044
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0021 0.0043 0.0043
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.004 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0015 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.1629 0.5572 0.5572
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0022 0.004
Trypanosoma cruzi target of rapamycin kinase 3 0.0015 0.0024 0.0023
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0013 0.0013 0.0013
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0134 0.024
Giardia lamblia Kinase, CMGC MAPK 0.0029 0.0071 0.0105
Brugia malayi ecdysone receptor 0.0015 0.0022 0.0022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0097 0.008
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.004 0.004
Echinococcus granulosus zinc finger protein 0.0011 0.0009 0.0016
Echinococcus granulosus serine protein kinase ATM 0.0021 0.0043 0.0078
Onchocerca volvulus 0.0027 0.0063 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0021 0.0042 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0099 0.0312 0.0312
Echinococcus multilocularis cpg binding protein 0.004 0.0107 0.0192
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.004 0.0072
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.004 0.0072
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.008 0.0144
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.008 0.008
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0097 0.0645
Echinococcus multilocularis nAChR subunit 0.0011 0.0008 0.0014
Brugia malayi hypothetical protein 0.0022 0.0044 0.0044
Brugia malayi hypothetical protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.01 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Schistosoma mansoni sex comb on midleg homolog 0.0023 0.0048 0.0086
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.005 0.0143 0.0256
Onchocerca volvulus Glucosylceramidase homolog 0.0075 0.0228 0.0409
Brugia malayi MH2 domain containing protein 0.0019 0.0037 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0113 0.036 0.0646
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.004 0.004
Schistosoma mansoni nuclear receptor 0.0015 0.0022 0.004
Echinococcus granulosus intermediate filament protein 0.0012 0.0011 0.002
Brugia malayi hypothetical protein 0.0033 0.0085 0.0085
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0026 0.0059 0.0106
Brugia malayi RNA binding protein 0.0113 0.036 0.036
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.2917 1 1
Leishmania major ATP-dependent phosphofructokinase 0.0046 0.013 0.0113
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0034 0.0088 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0071 0.0071
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0063 0.0063
Mycobacterium ulcerans lipase LipD 0.0067 0.0202 0.0197
Mycobacterium ulcerans hypothetical protein 0.0067 0.0202 0.0197
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Echinococcus multilocularis 6 phosphofructokinase 0.0046 0.013 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0032 0.008 0.0144
Schistosoma mansoni cpg binding protein 0.004 0.0107 0.0192
Schistosoma mansoni zinc finger protein 0.0015 0.0022 0.004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0071 0.0071
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0022 0.004
Brugia malayi beta-lactamase family protein 0.0067 0.0202 0.0202
Mycobacterium tuberculosis Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) 0.0232 0.0768 0.5291
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0016 0.0026 0.0124
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0075 0.0228 0.0409
Schistosoma mansoni hypothetical protein 0.0042 0.0114 0.0205
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0114 0.0363 0.0363
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0067 0.0202 0.1372
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.004 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0114 0.0363 0.0363
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.1629 0.5572 1
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.004 0.0072
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.008 0.0246 0.0246
Toxoplasma gondii histone lysine methyltransferase SET1 0.0071 0.0216 0.0212
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0021 0.0042 0.0039
Onchocerca volvulus 0.0037 0.0097 0.0174
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.008 0.008
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0031 0.0077 0.0137
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0024 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.005 0.0089
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0031 0.0077 0.0076
Plasmodium vivax polyprenol reductase, putative 0.1629 0.5572 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0097 0.0173
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0063 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Entamoeba histolytica hypothetical protein 0.005 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.008 0.0144
Schistosoma mansoni hypothetical protein 0.009 0.0281 0.0505
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0022 0.004
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0046 0.013 0.0126
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0022 0.004
Echinococcus granulosus nAChR subunit 0.002 0.004 0.0072
Echinococcus multilocularis synaptic glycoprotein sc2 0.1629 0.5572 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0058 0.0169 0.0304
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0067 0.0202 0.1372
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Echinococcus granulosus histone lysine methyltransferase setb 0.0023 0.005 0.0089
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0002 0.0004
Schistosoma mansoni cpg binding protein 0.004 0.0107 0.0192
Echinococcus multilocularis peroxidasin 0.0027 0.0063 0.0114
Brugia malayi ecdysteroid receptor 0.0032 0.008 0.008
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0097 0.7157
Brugia malayi MH2 domain containing protein 0.0019 0.0037 0.0037
Toxoplasma gondii exonuclease III APE 0.0037 0.0097 0.0093
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.2917 1 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0029 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0006
Mycobacterium tuberculosis Conserved protein 0.0067 0.0202 0.1372
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0017 0.0012
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0024 0.0042
Onchocerca volvulus 0.0114 0.0362 0.065
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.2917 1 1
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0042 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0022 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.008 0.008
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1629 0.5572 0.5572
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0022 0.0046 0.0083
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0024 0.0042
Brugia malayi Smad1 0.0019 0.0037 0.0037
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0024 0.0042
Schistosoma mansoni hypothetical protein 0.005 0.0143 0.0256
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0085 0.0085
Echinococcus granulosus geminin 0.0575 0.1947 0.3494
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Onchocerca volvulus 0.0015 0.0022 0.004
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.004 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.004 0.0072
Echinococcus multilocularis epidermal growth factor receptor 0.008 0.0245 0.044
Onchocerca volvulus 0.002 0.004 0.0072
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0097 0.0164
Brugia malayi hypothetical protein 0.005 0.0143 0.0143
Schistosoma mansoni apoferritin-2 0.0016 0.0026 0.0047
Schistosoma mansoni tyrosine kinase 0.0079 0.0242 0.0434
Schistosoma mansoni tar DNA-binding protein 0.0113 0.036 0.0646
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0009 0.0002 0.0004
Echinococcus granulosus epidermal growth factor receptor 0.0149 0.0482 0.0864
Loa Loa (eye worm) Smad1 0.0019 0.0037 0.0037
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0023 0.0048 0.0086
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0028 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Loa Loa (eye worm) glutamate receptor 0.0018 0.0032 0.0032
Mycobacterium ulcerans naphthoate synthase 0.0232 0.0768 0.0763
Echinococcus granulosus muscleblind protein 0.007 0.0211 0.0378
Onchocerca volvulus 0.002 0.004 0.0072
Loa Loa (eye worm) 6-phosphofructokinase 0.0046 0.013 0.013
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.008 0.0246 0.0246
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.2917 1 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0017
Mycobacterium ulcerans hypothetical protein 0.2917 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0022 0.004
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.004 0.0072
Trypanosoma cruzi major cysteine proteinase, putative 0.002 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0028
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0017 0.0028 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0132 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0028
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0028 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0009 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.1629 0.5572 0.5572
Onchocerca volvulus 0.1629 0.5572 1
Entamoeba histolytica phosphofructokinase, putative 0.0046 0.013 0.0129
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.004 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0009 0.0002 0.0004
Loa Loa (eye worm) isocitrate dehydrogenase 0.0021 0.0042 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0017 0.0012
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0097 1
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.008 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.008 0.0144
Schistosoma mansoni hypothetical protein 0.0112 0.0354 0.0635
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0071 0.0071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0017 0.0017
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0009 0.0002 0.0002
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0063 0.0114
Onchocerca volvulus 0.0011 0.0008 0.0014
Schistosoma mansoni peroxidasin 0.0027 0.0063 0.0114
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Brugia malayi conserved hypotetical protein 0.0015 0.0022 0.0022
Schistosoma mansoni tyrosine kinase 0.0079 0.0242 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Entamoeba histolytica hypothetical protein 0.005 0.0143 0.0142
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0063 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Mycobacterium tuberculosis Conserved protein 0.0067 0.0202 0.1372
Echinococcus multilocularis expressed protein 0.0016 0.0026 0.0047
Echinococcus granulosus glycine receptor subunit beta 0.002 0.004 0.0072
Mycobacterium tuberculosis Probable lipase LipE 0.0067 0.0202 0.1372
Schistosoma mansoni ap endonuclease 0.0037 0.0097 0.0173
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Brugia malayi 6-phosphofructokinase 0.0046 0.013 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0015 0.0022 0.004
Onchocerca volvulus 0.002 0.004 0.0072
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0029 0.0071 0.0054
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus dnaJ subfamily B 0.0174 0.057 0.1023
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0024 0.0023
Echinococcus multilocularis musashi 0.0012 0.0011 0.002
Leishmania major hypothetical protein, conserved 0.0033 0.0085 0.0068
Brugia malayi Metabotropic glutamate receptor precursor. 0.0018 0.0032 0.0032
Loa Loa (eye worm) glutaminase 0.0132 0.0424 0.0424
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.004 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0079 0.0241 0.0432
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0021 0.0042 0.0067
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0071 0.0071
Plasmodium falciparum polyprenol reductase, putative 0.1629 0.5572 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0004 0.0003
Echinococcus multilocularis neuropeptide s receptor 0.0437 0.1474 0.2645
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0002 0.0004
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0037 0.0066
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0017 0.0028 0.005
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0011 0.0011
Schistosoma mansoni peroxidasin 0.0027 0.0063 0.0114
Schistosoma mansoni hypothetical protein 0.0042 0.0114 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.0246 0.0441
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0063 0.0063
Schistosoma mansoni nAChR subunit 0.002 0.004 0.0072
Brugia malayi beta-lactamase 0.0067 0.0202 0.0202
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.008 0.0144
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0028
Schistosoma mansoni nAChR subunit 0.0009 0.0002 0.0004
Brugia malayi hypothetical protein 0.0271 0.0903 0.0903
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0042 0.0114 0.0205
Loa Loa (eye worm) MH2 domain-containing protein 0.0284 0.0948 0.0948
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0024 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.008 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0017 0.0012
Brugia malayi Cation transporter family protein 0.002 0.004 0.004
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0174 0.057 0.057
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.008 0.0144
Onchocerca volvulus Peroxidase homolog 0.0027 0.0063 0.0114
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0024 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.0284 0.0948 0.0948
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.004 0.004
Echinococcus multilocularis muscleblind protein 1 0.007 0.0211 0.0378
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.004 0.004
Onchocerca volvulus 0.0012 0.0011 0.002
Onchocerca volvulus Peroxidase homolog 0.0027 0.0063 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0028 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0022 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0202 0.0362
Loa Loa (eye worm) phosphofructokinase 0.0046 0.013 0.013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0013 0.0014 0.0025
Mycobacterium tuberculosis Possible penicillin-binding protein 0.043 0.1449 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Schistosoma mansoni tyrosine kinase 0.008 0.0245 0.044
Brugia malayi nuclear hormone receptor 0.0032 0.008 0.008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0042 0.0114 0.0114
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0015 0.0022 0.0039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0024 0.0024
Schistosoma mansoni survival motor neuron protein 0.0112 0.0354 0.0635
Trichomonas vaginalis glucosylceramidase, putative 0.0079 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Plasmodium vivax SET domain protein, putative 0.0015 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.004 0.0072
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0011 0.0011
Echinococcus multilocularis isocitrate dehydrogenase 0.0021 0.0042 0.0076
Schistosoma mansoni smad 0.0019 0.0037 0.0066
Loa Loa (eye worm) hypothetical protein 0.009 0.0281 0.0281
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0088 0.0083
Trichomonas vaginalis ferritin, putative 0.0016 0.0026 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.008 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0097 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Brugia malayi Isocitrate dehydrogenase 0.0021 0.0042 0.0042
Brugia malayi PHD-finger family protein 0.0014 0.0018 0.0018
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.2917 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.008 0.0144
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0025 0.0055 0.0054
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0011 0.0008 0.0014
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0004 0.0006
Schistosoma mansoni nuclear receptor 0.0015 0.0022 0.004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1144 0.3905 0.7008
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0031 0.0077 0.0077
Toxoplasma gondii hypothetical protein 0.0028 0.0067 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0017 0.0017
Onchocerca volvulus 0.0014 0.0017 0.0031
Giardia lamblia Synaptic glycoprotein SC2 0.1629 0.5572 1
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Onchocerca volvulus Putative nachr subunit 0.002 0.004 0.0072
Echinococcus multilocularis mitogen activated protein kinase 3 0.0029 0.0071 0.0128
Plasmodium vivax 6-phosphofructokinase, putative 0.0013 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni smad1 5 8 and 0.0019 0.0037 0.0066
Brugia malayi CXXC zinc finger family protein 0.0037 0.0097 0.0097
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1629 0.5572 0.5572
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0097 0.0096
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.005 0.0143 0.0256
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.004 0.0072
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0034 0.0088 0.0584
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0024 0.0023
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0009 0.0002 0.0002
Echinococcus granulosus smad 0.0019 0.0037 0.0066
Brugia malayi beta-lactamase family protein 0.0067 0.0202 0.0202
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.004 0.0072
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0021 0.0042 0.0076
Onchocerca volvulus 0.0009 0.0002 0.0004
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0009 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0063 0.0063
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0071 0.0071
Loa Loa (eye worm) beta-lactamase 0.0067 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0083 0.0254 0.025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.003 0.0073 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.008 0.008
Schistosoma mansoni Smad4 0.0019 0.0037 0.0066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0022 0.004
Mycobacterium ulcerans hypothetical protein 0.0056 0.0162 0.0157
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0013 0.0013 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0013 0.0014 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0112 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0046
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0174 0.057 0.0566
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.008 0.0144
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0097 0.015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.0246 0.0441
Treponema pallidum bacterioferrin (TpF1) 0.0016 0.0026 0.112
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.008 0.0144
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1629 0.5572 0.5571
Mycobacterium tuberculosis Probable hydrolase 0.0067 0.0202 0.1372
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0024 0.0023
Loa Loa (eye worm) blistered cuticle protein 3 0.0027 0.0063 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0113 0.036 0.0646
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.008 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.008 0.008
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0037 0.0066
Onchocerca volvulus 0.0112 0.0354 0.0635
Trichomonas vaginalis set domain proteins, putative 0.0114 0.0362 0.0362
Brugia malayi nuclear receptor NHR-88 0.0032 0.008 0.008
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.003 0.0074 0.0132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0024 0.0024
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) LGC-31 protein 0.002 0.004 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.0008
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.004 0.0072
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0009 0.0002 0.0004
Onchocerca volvulus 0.002 0.004 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0017 0.0095
Echinococcus granulosus FTZ F1 alpha 0.0032 0.008 0.0144
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.1629 0.5572 0.5572
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0017 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Echinococcus granulosus metabotropic glutamate receptor 5 0.0022 0.0046 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Echinococcus granulosus metabotropic glutamate receptor 2 0.0015 0.0022 0.0039
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0254 0.0254
Echinococcus granulosus tar DNA binding protein 0.0113 0.036 0.0646
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0058 0.0057
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0008 0.0014
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0028 0.0051
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0037 0.0066
Brugia malayi nuclear hormone receptor 0.0015 0.0022 0.0022
Echinococcus multilocularis tar DNA binding protein 0.0113 0.036 0.0646
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.008 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0009 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0011 0.0007 0.0007
Onchocerca volvulus 0.0011 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0187 0.0614 0.0614
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0015 0.0022 0.004
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.004 0.0072
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0021 0.0042 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Schistosoma mansoni smad1 5 8 and 0.0019 0.0037 0.0066
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0046 0.013 0.0129
Mycobacterium ulcerans bacterioferritin BfrA 0.0016 0.0026 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0042 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0004 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.004 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0017 0.0017
Brugia malayi Muscleblind-like protein 0.007 0.0211 0.0211
Schistosoma mansoni intermediate filament proteins 0.0012 0.0011 0.002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0015 0.0024 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0097 0.0173
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.008 0.0144
Brugia malayi mbt repeat family protein 0.0023 0.0048 0.0048
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0202 0.0201
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0046 0.013 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.008 0.008
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0024 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Echinococcus multilocularis zinc finger protein 0.0011 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0042 0.0114 0.0205
Trypanosoma brucei PAB1-binding protein , putative 0.0033 0.0085 0.0082
Schistosoma mansoni bromodomain containing protein 0.0032 0.0079 0.0142
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0021 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Mycobacterium leprae PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE) 0.0232 0.0768 1
Loa Loa (eye worm) hypothetical protein 0.1629 0.5572 0.5572
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0043 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0022 0.004
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0042 0.0039
Echinococcus granulosus neuropeptide s receptor 0.0437 0.1474 0.2645
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0023 0.005 0.005
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0021 0.0042 0.0067
Schistosoma mansoni hypothetical protein 0.0042 0.0114 0.0205
Toxoplasma gondii ABC1 family protein 0.0067 0.0202 0.0198
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.004 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0202 0.0201
Echinococcus granulosus mitogen activated protein kinase 3 0.0029 0.0071 0.0128
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.008 0.0144
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0022 0.0022
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0097 0.0302 0.0543
Leishmania major phosphatidylinositol kinase related protein, putative 0.0016 0.0024 0.0007
Loa Loa (eye worm) mbt repeat family protein 0.0023 0.0048 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0132 0.0425 0.0425
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0246 0.0441
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0254 0.0237
Echinococcus granulosus ferritin 0.0016 0.0026 0.0047
Schistosoma mansoni ferritin 0.0016 0.0026 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0015 0.0024 0.002
Onchocerca volvulus 0.002 0.004 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0013 0.0013 1
Loa Loa (eye worm) GABA receptor subunit 0.0011 0.0008 0.0008
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.004 0.0072
Echinococcus granulosus nAChR subunit 0.0011 0.0008 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Schistosoma mansoni apoferritin-2 0.0016 0.0026 0.0047
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.004 0.0072
Loa Loa (eye worm) MBCTL1 0.0026 0.0059 0.0059
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0024 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.008 0.008
Onchocerca volvulus 0.0015 0.0022 0.004
Echinococcus multilocularis Smad4 0.0019 0.0037 0.0066
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.004 0.004
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0037 0.0037
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.004 0.0072
Echinococcus granulosus lamin 0.0012 0.0011 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0071 0.0071
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Onchocerca volvulus 0.0027 0.0063 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0014 0.0017 0.0012
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0026 0.0059 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.008 0.008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0013 0.0013 0.0015
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.008 0.0144
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0085 0.0144
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0022 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0071 0.0128
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.2917 1 1
Schistosoma mansoni ferritin 0.0016 0.0026 0.0047
Schistosoma mansoni 6-phosphofructokinase 0.0046 0.013 0.0233
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0024 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0113 0.036 0.0646
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1629 0.5572 0.5572
Echinococcus multilocularis smad 0.0019 0.0037 0.0066
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0031 0.0077 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0024 0.002
Schistosoma mansoni tyrosine kinase 0.0048 0.0134 0.024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0042 0.0076
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0067 0.0202 0.1372
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) PHD-finger family protein 0.001 0.0003 0.0003
Schistosoma mansoni myelin transcription factor 1 myt1 0.0026 0.0059 0.0106
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0028 0.0051
Brugia malayi glutaminase DH11.1 0.0132 0.0424 0.0424
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0022 0.004
Brugia malayi TAR-binding protein 0.0113 0.036 0.036
Brugia malayi nuclear receptor RXR 0.0015 0.0022 0.0022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0097 0.0096
Brugia malayi Furin-like cysteine rich region family protein 0.0149 0.0482 0.0482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Brugia malayi MH1 domain containing protein 0.0019 0.0037 0.0037
Brugia malayi Latrophilin receptor protein 2 0.0042 0.0114 0.0114
Loa Loa (eye worm) pax transcription factor protein 2 0.0107 0.0337 0.0337
Brugia malayi MAP kinase sur-1 0.0029 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Schistosoma mansoni tyrosine kinase 0.0149 0.0482 0.0864
Brugia malayi Bromodomain containing protein 0.0037 0.0098 0.0098
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0202
Brugia malayi hypothetical protein 0.0017 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Onchocerca volvulus 0.0027 0.0063 0.0114
Brugia malayi Pax transcription factor protein 2 0.0107 0.0337 0.0337
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Echinococcus multilocularis insulin receptor 0.0048 0.0134 0.024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0022 0.004
Loa Loa (eye worm) CXXC zinc finger family protein 0.0037 0.0097 0.0097
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.008 0.0144
Onchocerca volvulus 0.002 0.004 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Brugia malayi hypothetical protein 0.0027 0.0063 0.0063
Echinococcus multilocularis ferritin 0.0016 0.0026 0.0047
Mycobacterium ulcerans bacterioferritin BfrB 0.0016 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Mycobacterium tuberculosis Conserved protein 0.0067 0.0202 0.1372
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.1629 0.5572 1
Brugia malayi steroid hormone receptor 0.0032 0.008 0.008
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.008 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0004 0.0006
Echinococcus multilocularis polycomb protein SCMH1 0.0023 0.0048 0.0086
Leishmania major mitochondrial DNA polymerase beta 0.0174 0.057 0.0554
Echinococcus granulosus insulin receptor 0.0048 0.0134 0.024
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis muscleblind protein 0.007 0.0211 0.0378
Onchocerca volvulus 0.0009 0.0002 0.0004
Echinococcus multilocularis lamin dm0 0.0012 0.0011 0.002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.008 0.008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0022 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.0246 0.0441
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0015 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0032 0.008 0.0144
Loa Loa (eye worm) hypothetical protein 0.007 0.0211 0.0211
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0016 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Brugia malayi Pre-SET motif family protein 0.01 0.0315 0.0315
Echinococcus multilocularis geminin 0.0575 0.1947 0.3494
Echinococcus multilocularis epidermal growth factor receptor 0.0149 0.0482 0.0864
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0025 0.0055 0.0051
Echinococcus granulosus cpg binding protein 0.004 0.0107 0.0192
Schistosoma mansoni synaptic glycoprotein sc2 related 0.1629 0.5572 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0046 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0174 0.057 0.1023
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0022 0.004
Schistosoma mansoni smad1 5 8 and 0.0019 0.0037 0.0066
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.004 0.0072
Brugia malayi hypothetical protein 0.0547 0.1852 0.1852
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0246 0.0441
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.004 0.004
Loa Loa (eye worm) glutaminase 2 0.0132 0.0424 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Schistosoma mansoni transcription factor LCR-F1 0.005 0.0143 0.0256
Mycobacterium tuberculosis Probable lipase LipD 0.0067 0.0202 0.1372
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0024 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0029 0.0071 0.0068
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0024 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0058 0.0057
Onchocerca volvulus 0.0271 0.0903 0.1621
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0013 0.0013 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0032 0.008 0.0144
Entamoeba histolytica steroid 5-alpha reductase, putative 0.2917 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0058 0.0057
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0174 0.057 0.057
Echinococcus multilocularis nAChR subunit 0.002 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Echinococcus multilocularis 0.0046 0.0128 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0042 0.0114 0.0205
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0042 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.008 0.0245 0.044
Schistosoma mansoni sex comb on midleg homolog 0.0023 0.0048 0.0086
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0075 0.0228 0.0228
Schistosoma mansoni nAChR subunit 0.0009 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0547 0.1852 0.1852
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0023 0.005 0.0089
Schistosoma mansoni lamin 0.0012 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0059
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0029 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Brugia malayi MH1 domain containing protein 0.0011 0.0007 0.0007
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.002 0.004 0.0073
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0063 0.0063
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0109 0.0344 0.0344
Trichomonas vaginalis phosphofructokinase, putative 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0017 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0024 0.0042
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Onchocerca volvulus 0.0023 0.0048 0.0086
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0202 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0132 0.0425 0.0425
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0028 0.0028
Schistosoma mansoni metabotropic glutamate receptor 0.0015 0.0022 0.0039
Echinococcus multilocularis survival motor neuron protein 1 0.0547 0.1852 0.3323
Brugia malayi intermediate filament protein 0.0012 0.0011 0.0011
Brugia malayi MH1 domain containing protein 0.0019 0.0037 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0042 0.0114 0.0114
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.008 0.0144
Loa Loa (eye worm) hypothetical protein 0.0271 0.0903 0.0903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Brugia malayi tailless protein 0.0015 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0075 0.0228 0.0228
Loa Loa (eye worm) TK/EGFR protein kinase 0.0149 0.0482 0.0482
Toxoplasma gondii phosphofructokinase PFKII 0.0013 0.0013 0.001
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.004 0.004
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.008 0.0144
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0002 0.0002
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0031 0.0077 0.006
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0097 0.0091
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0097 0.0097
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.008 0.0144
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0023 0.0048 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0113 0.036 0.0646
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0097 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0016 0.0024 0.0023
Echinococcus multilocularis beta LACTamase domain containing family member 0.0067 0.0202 0.0362
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0024 0.0007
Echinococcus granulosus fetal alzheimer antigen falz 0.0013 0.0014 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.008 0.0144
Schistosoma mansoni metabotropic glutamate receptor 0.0009 0 0.0001
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0097 0.0097
Toxoplasma gondii 6-phosphofructokinase 0.0013 0.0013 0.001
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0134 0.024
Echinococcus granulosus Smad4 0.0019 0.0037 0.0066
Brugia malayi Cation transporter family protein 0.002 0.004 0.004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0132 0.0425 0.0425
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0042 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0014 0.0017 0.0012
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0031 0.0077 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.004 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0014 0.0017 0.0031
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.008 0.008
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0022 0.0022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0069 0.0208 0.0203
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0037 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Onchocerca volvulus 0.0012 0.0011 0.002
Schistosoma mansoni 6-phosphofructokinase 0.0046 0.013 0.0233
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0067 0.0202 0.0202
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0013 0.0013 0.0013
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0021 0.0042 0.0076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0246 0.0441
Trichomonas vaginalis phosphofructokinase, putative 0.0046 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Schistosoma mansoni ferritin light chain 0.0016 0.0026 0.0047
Brugia malayi phosphofructokinase 0.0046 0.013 0.013
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.2917 1 1
Schistosoma mansoni hypothetical protein 0.0575 0.1947 0.3494
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0042 0.0114 0.0205
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1629 0.5572 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Schistosoma mansoni acetylcholine receptor-related 0.0009 0.0002 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0009 0.0002 0.0004
Mycobacterium ulcerans hypothetical protein 0.0014 0.0017 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0075 0.0228 0.0228
Echinococcus granulosus transcription factor Dp 1 0.0018 0.0032 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.008 0.0144
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.004 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0114 0.0363 0.0363
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0013 0.0013 0.001
Echinococcus granulosus 6 phosphofructokinase 0.0046 0.013 0.0233
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Entamoeba histolytica acyl-coA synthetase, putative 0.0014 0.0017 0.0017
Leishmania major cathepsin L-like protease 0.0025 0.0058 0.0041
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.0046 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0084
Echinococcus granulosus GPCR family 2 0.0042 0.0114 0.0205
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0004 0.0006
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0097 0.0302 0.0543
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.004 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.008 0.0144
Toxoplasma gondii LsmAD domain-containing protein 0.0033 0.0085 0.0082
Entamoeba histolytica phosphofructokinase, putative 0.0046 0.013 0.0129
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0042 0.0076
Brugia malayi hypothetical protein 0.0017 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0109 0.0344 0.0344
Mycobacterium leprae conserved hypothetical protein 0.0067 0.0202 0.2458
Brugia malayi nuclear receptor RXR 0.0017 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Schistosoma mansoni ap endonuclease 0.0037 0.0097 0.0173
Brugia malayi Blistered cuticle protein 3 0.0027 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0011
Loa Loa (eye worm) TAR-binding protein 0.0113 0.036 0.036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0067 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0027 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0025 0.0058 0.0054
Plasmodium vivax 6-phosphofructokinase, putative 0.0013 0.0013 0.0015

Activities

Activity type Activity value Assay description Source Reference
MFC (functional) = 6.3 ug ml-1 Minimum fungicidal concentration was determined against C. albicans 3153A strain ChEMBL. 2299651
MFC (functional) = 6.3 ug ml-1 Minimum fungicidal concentration was determined against C. albicans 3153A strain ChEMBL. 2299651
MIC (functional) = 3.1 ug ml-1 Minimum inhibitory concentration was determined against C. albicans 3153A strain ChEMBL. 2299651
MIC (functional) = 3.1 ug ml-1 Minimum inhibitory concentration was determined against C. albicans 3153A strain ChEMBL. 2299651
No. of survivors (functional) = 4 The number of survivors/total infected at day 14 was determined after (ip) administration of 2 mg/kg in C. albicans infected mice; 4/10 ChEMBL. 2299651
No. of survivors (functional) = 4 The number of survivors/total infected at day 14 was determined after (ip) administration of 2 mg/kg in C. albicans infected mice; 4/10 ChEMBL. 2299651

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.